CN220568473U

CN220568473U - Reagent taking and placing device and cell enrichment and dyeing integrated equipment

Info

Publication number: CN220568473U
Application number: CN202321925302.0U
Authority: CN
Inventors: 肖乐义; 刘元柱; 李东; 杨勤英; 薛冰; 许元红; 牛玉生; 于成; 米明仁; 张腾业; 李娟�
Original assignee: Qingdao Yanding Biomedical Technology Co ltd
Current assignee: Qingdao Yanding Biomedical Technology Co ltd
Priority date: 2023-07-20
Filing date: 2023-07-20
Publication date: 2024-03-08
Anticipated expiration: 2033-07-20

Abstract

The utility model belongs to the technical field of biological medicines, and discloses a reagent taking and placing device and cell enrichment and dyeing integrated equipment. The reagent taking and placing device provided by the utility model comprises: a reagent accommodating device for moving to a fixed position to suck or put in the reagent stored in the reagent accommodating device; the vacuumizing device comprises a vacuum cylinder connected with the reagent accommodating device and a piston assembly capable of reciprocating along the wall of the vacuum cylinder; the driving device is used for driving the vacuum cylinder and the piston assembly to generate relative motion, so that air suction and decompression are carried out in the reagent accommodating device, and the reagent is sucked into the reagent accommodating device; or the reagent container is aerated and pressurized to make the reagent container throw the reagent. According to the scheme provided by the utility model, the driving device drives the vacuumizing device to enable the vacuum cylinder and the piston assembly to move relatively, so that the air pressure in the reagent accommodating device is changed, and the extraction or the throwing of the reagent is realized. The scheme is simple to operate, and the reagent taking and placing efficiency is high.

Description

Reagent taking and placing device and cell enrichment and dyeing integrated equipment

Technical Field

The utility model belongs to the field of biological medicine, and particularly relates to a reagent taking and placing device and cell enrichment and dyeing integrated equipment.

Background

The pharmaceutical industry and the biomedical engineering industry are two main posts of modern medicine industry, the biomedical industry consists of biotechnology industry and medicine industry, the biomedical engineering is the principle and method of comprehensive application life science and engineering science, the structure, the function and other life phenomena of human body are known in multiple levels in molecules, cells, tissues, organs and even the whole human body system from engineering perspective, and the total name of artificial materials, products, devices and system technology for disease prevention, disease treatment, human body function assistance and health care is researched.

In recent years, in the field of biomedical engineering, several emerging tumor diagnostic detection techniques, such as detection methods for circulating tumor DNA, circulating Tumor Cells (CTCs), known as liquid biopsies, have emerged. According to researches, the existence of CTC can be found in peripheral blood before solid tumor formation, so that CTC detection is very suitable for early screening and early diagnosis of malignant tumors, and CTC detection has good effects on prognosis of malignant tumors, disease progress monitoring, recurrence prediction, postoperative tiny focus monitoring of malignant tumors and design and treatment effect monitoring of targeted drug treatment, and is an advanced method for early screening and diagnosis of malignant tumors at present. The method can avoid trauma to the patient, is convenient for obtaining the test sample, can be widely applied to immunological research detection, gene research detection or microorganism detection, and can be even applied to biological chips and organoid research and development. The current mainstream operation method is to enrich and then detect the circulating tumor cells. In the detection process, the collected body fluid needs to be subjected to steps such as suction printing, enrichment, dyeing and the like, and reagents are required to be added for many times in each step, so that the types of the reagents are more. At present, when the existing reagent in the market is taken and put, the reagent is taken and put manually by a worker, and the efficiency of taking and putting manually is reduced, so that the reagent identification efficiency is greatly reduced.

In view of this, the present utility model has been made.

Disclosure of Invention

The utility model aims to solve the technical problem of overcoming the defects of the prior art and providing a reagent taking and placing device with high reagent taking and placing efficiency and integrated cell enrichment and dyeing equipment.

In order to solve the technical problems, the utility model adopts the basic conception of the technical scheme that:

in one aspect, a reagent handling apparatus is provided.

Wherein, reagent is got and is put device includes:

reagent holding means for holding a reagent;

the vacuumizing device comprises a vacuum cylinder connected with the reagent accommodating device and a piston assembly capable of reciprocating along the wall of the vacuum cylinder;

the driving device is used for driving the vacuum cylinder and the piston assembly to generate relative motion, and sucking the reagent into the reagent accommodating device by exhausting and decompressing in the reagent accommodating device; or the reagent container is aerated and pressurized to make the reagent container throw the reagent.

The reagent taking and placing device provided by the utility model not only comprises a reagent accommodating device for storing the reagent, but also comprises a vacuumizing device fixedly connected with the driving device. When the device is used, the driving device drives the vacuumizing device to enable the vacuum cylinder and the piston assembly to move relatively, so that the reagent is extracted or put in. The scheme is simple to operate, and the reagent taking and placing efficiency is high.

Further, the piston assembly comprises a piston and a push rod, and one end of the push rod is fixedly connected with the piston;

the other end of the push rod is fixedly arranged, and the driving device drives the vacuum cylinder to reciprocate.

Further, the vacuum pumping device further comprises:

and the limiting component is in limiting fit with the other end of the push rod.

Further, the limiting component comprises a first limiting plate which is perpendicular to the moving direction of the vacuum cylinder;

the other end of the push rod is fixed on the first limiting plate.

Further, the limiting component comprises a first limiting plate and a second limiting plate which are arranged perpendicular to the moving direction of the vacuum cylinder;

a gap is formed between the first limiting plate and the second limiting plate;

the first limiting plate is provided with a groove;

the other end of the push rod is provided with a fixed part with a section larger than the section of the push rod;

the push rod is inserted into the groove to enable the fixing part to be arranged in a gap between the first limiting plate and the second limiting plate.

Further, the reagent taking and placing device further comprises a fixing plate, and at least one clamping seat for installing the vacuum cylinder is arranged on the fixing plate.

Further, the reagent picking and placing device further comprises:

one end of the transmission screw rod is connected with the driving device and is driven to rotate by the driving device;

the fixed plate is connected with a sliding block on the transmission screw rod and moves along the extending direction of the transmission screw rod through the sliding block.

Further, the vacuum cylinder is connected with the reagent holding device through a first communication pipe.

Further, the vacuumizing device and the reagent accommodating device are arranged up and down;

the vacuumizing device is arranged on the operation plate, and the operation plate is provided with a through hole for the first communication pipe to pass through.

On the other hand, still provide a cell enrichment dyeing integration equipment, cell enrichment dyeing integration equipment includes above-mentioned a reagent and gets puts the device.

The cell enrichment and dyeing integrated device provided by the utility model has the advantages that the reagent taking and placing device is included, so that the operation is more convenient and the efficiency is higher in the process of taking and placing the reagent.

By adopting the technical scheme, compared with the prior art, the utility model has the following beneficial effects.

1. The scheme provided by the utility model not only comprises a reagent accommodating device for storing the reagent, but also comprises a vacuumizing device fixedly connected with the driving device. When the device is used, the driving device drives the vacuumizing device to enable the vacuum cylinder and the piston assembly to move relatively, so that the reagent is extracted or put in. The scheme is simple to operate and high in efficiency.

2. The scheme provided by the utility model is provided with a fixing plate, wherein the fixing plate is provided with at least one clamping seat for installing the vacuum cylinder. When the device is used, the driving device can enable the plurality of vacuum cylinders on the fixing plate to suck or suck air at the same time, so that the reagent taking and placing devices can simultaneously execute the sucking and placing of the reagents.

The following describes the embodiments of the present utility model in further detail with reference to the accompanying drawings.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the utility model. It is evident that the drawings in the following description are only examples, from which other drawings can be obtained by a person skilled in the art without the inventive effort. In the drawings:

FIG. 1 is a top view of an evacuation device of the present utility model;

FIG. 2 is a front view of a first limiting plate of the vacuum extractor of the present utility model;

FIG. 3 is a left side view of the vacuum apparatus of the present utility model excluding the first and second limiting plates;

FIG. 4 is a schematic view of the reagent holding apparatus of the present utility model.

In the figure: 100. a reagent taking and placing device; 101. a vacuum pumping device; 1011. a vacuum cylinder; 1012. a driving device; 1013. a transmission screw; 1014. a push rod; 1015. a first limiting plate; 1016. a second limiting plate; 1017. a fixing member; 1018. a fixing plate; 1019. a clamping seat; 1020. a first communication pipe; 1021. an operation panel; 1022. a groove;

110. a reagent accommodating device; 1101. a reagent accommodating tube; 1102. a first support frame; 1103. a second support frame; 1104. a second communicating pipe; 1105. a needle.

It should be noted that these drawings and the written description are not intended to limit the scope of the inventive concept in any way, but to illustrate the inventive concept to those skilled in the art by referring to the specific embodiments.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions in the embodiments will be clearly and completely described with reference to the accompanying drawings in the embodiments of the present utility model, and the following embodiments are used to illustrate the present utility model, but are not intended to limit the scope of the present utility model.

In the description of the present utility model, it should be noted that the directions or positional relationships indicated by the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model.

In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.

As shown in fig. 1 to 4, the present utility model provides a reagent picking and placing device.

The reagent dispensing device 100 includes:

reagent holding means for holding a reagent;

the vacuumizing device 101 comprises a vacuum cylinder 1011 connected with the reagent accommodating device and a piston assembly capable of reciprocating along the wall of the vacuum cylinder 1011;

the driving device 1012 is used for driving the vacuum cylinder 1011 and the piston assembly to generate relative motion, so that the air in the reagent accommodating device is pumped and decompressed, and the reagent is sucked into the reagent accommodating device; or the reagent container is aerated and pressurized to make the reagent container throw the reagent.

When the scheme provided by the utility model is used, the driving device drives the vacuumizing device to enable the vacuum cylinder and the piston assembly to move relatively, so that the reagent is extracted or put in. The scheme does not need manual operation, and is convenient to operate and high in efficiency.

The integrated cell enrichment and staining equipment comprises the reagent taking and placing device.

Example 1

As shown in fig. 1-3, this embodiment provides a reagent pick-and-place device.

Wherein, the reagent picking and placing device 100 comprises:

reagent holding means for holding a reagent;

the driving device 1012 is used for driving the vacuumizing device 101 to enable the vacuum cylinder 1011 and the piston assembly to move relatively, so that the air in the reagent accommodating device is pumped and decompressed, and the reagent is sucked into the reagent accommodating device; or the reagent container is aerated and pressurized to make the reagent container throw the reagent.

The reagent taking and placing device provided by the embodiment comprises a reagent accommodating device for accommodating a reagent, a vacuumizing device connected with the reagent accommodating device and a driving device for driving the vacuumizing device to move. The driving device drives the vacuumizing device to enable the vacuum cylinder and the piston assembly to move relatively, so that the pressure in the reagent containing device communicated with the vacuumizing device is reduced or increased, and reagent is sucked into the reagent containing device or is thrown out from the reagent containing device. The scheme can realize taking and placing of the reagent without manual operation of a user, and is convenient to operate and high in efficiency.

The solution of this embodiment further includes that the vacuum cylinder 1011 is connected to the reagent containing apparatus through a first communication pipe 1020.

The vacuumizing device 101 and the reagent accommodating device are arranged up and down;

the vacuum suction device 101 is mounted on an operation board 1021, and the operation board 1021 has a through hole through which the first communication pipe 1020 passes.

The vacuum pumping apparatus 101 provided in this embodiment includes a vacuum cylinder 1011 and a piston assembly disposed within the vacuum cylinder 1011 to move along the wall of the vacuum cylinder 1011. Wherein, the vacuum cylinder 1011 is connected with the reagent accommodating apparatus through a first communication pipe 1020. Specifically, the vacuumizing device 101 is mounted on an operation board 1021, and a through hole through which the first communication pipe 1020 passes is provided on the operation board 1021. The through holes may be provided only one, and the plurality of first communication pipes may pass through the same through hole. The device also can be provided with a plurality of through holes, the number of the through holes is not less than that of the vacuum cylinders, and the first communication pipe penetrates through two ends of the through holes to be respectively connected with the vacuum cylinders and the reagent containing device.

In the embodiment provided in this embodiment, the reagent accommodating device is disposed below the vacuumizing device 101, one end of the first communicating tube 1020 is connected to the vacuum cylinder 1011 of the vacuumizing device 101, and then extends to the lower side through the through hole on the operation board 1021, and the other end of the first communicating tube 1020 is connected to the reagent accommodating device. More specifically, the other end of the first communication pipe 1020 is connected to a reagent accommodating pipe of the reagent accommodating apparatus. When in use, the vacuumizing device 101 is used for sucking the reagent into the reagent accommodating tube by exhausting air from the reagent accommodating tube and decompressing; or the evacuating device 101 pressurizes the reagent accommodating tube by ventilation to allow the reagent accommodating tube to deliver the reagent.

In another aspect of this embodiment, the evacuation device is disposed below the reagent holding device. That is, the operation plate is still arranged between the vacuumizing device and the reagent accommodating device, and the vacuumizing device is suspended and fixedly arranged on the back surface of the operation plate.

In one embodiment provided in this embodiment, the vacuum cylinder 1011 of the vacuumizing device 101 is fixed, and the driving device 1012 drives the piston assembly to move so as to take and place the reagent.

In another aspect of this embodiment, the piston assembly is stationary and the drive device 1012 drives the vacuum cylinder 1011 to move to effect the removal and placement of the reagents.

Specifically, the piston assembly includes a piston and a pushrod 1014, one end of the pushrod 1014 being fixedly coupled to the piston;

the other end of the push rod 1014 is fixedly arranged, and the driving device 1012 drives the vacuum cylinder 1011 to reciprocate.

The vacuum pumping apparatus 101 further comprises:

and a limiting component which is in limiting fit with the other end of the push rod 1014.

The limiting component comprises a first limiting plate which is perpendicular to the moving direction of the vacuum cylinder;

the other end of the push rod is fixed on the first limiting plate.

This scheme is described in detail below:

the piston assembly provided in this embodiment includes a piston and a push rod 1014, the piston is installed in the vacuum cylinder 1011, one end of the push rod 1014 is fixedly connected with the piston, and the other end of the push rod 1014 is in limit fit with a limit component to realize the fixation of the push rod 1014. In this embodiment, since the push rod 1014 is stationary, the piston fixedly coupled to the push rod 1014 is also stationary. At this time, the driving device 1012 drives the vacuum cylinder 1011 to move, thereby increasing or decreasing the air pressure in the reagent accommodating device to take and place the reagent. It should be noted that the driving device in this embodiment is preferably a servo motor.

In this scheme, the limiting plate includes the first limiting plate of perpendicular setting, and the other end of push rod is fixed on first limiting plate through the mode of pasting. When the device is used, the positions of the piston and the push rod are fixed, the servo motor enables the vacuum cylinder to move to change the air pressure inside the vacuum cylinder, and therefore the reagent containing device connected with the vacuum cylinder can realize the extraction and the throwing of the reagent.

In another aspect of this embodiment, the limiting component includes a first limiting plate 1015 and a second limiting plate 1016 that are disposed perpendicular to the moving direction of the vacuum cylinder 1011;

a gap is formed between the first limit plate 1015 and the second limit plate 1016;

the first limiting plate 1015 has a groove 1022 thereon;

the other end of the push rod 1014 has a fixing member 1017 having a cross section larger than that of the push rod 1014;

the push rod 1014 is inserted into the groove 1022 such that the fixing member 1017 is disposed in the gap between the first and second limiting plates 1015 and 1016.

Specifically, the limiting component in limiting fit with the push rod 1014 includes a first limiting plate 1015 and a second limiting plate 1016. The first limiting plate 1015 and the second limiting plate 1016 are disposed in a direction perpendicular to the moving direction of the vacuum cylinder 1011. In the solution provided in this embodiment, the vacuumizing device 101 is horizontally disposed on the operation table, and the first limiting plate 1015 and the second limiting plate 1016 are vertically disposed on the operation table. In order to better fix the first limiting plate 1015 on the operation plate 1021, the first limiting plate 1015 further includes a mounting plate integrally formed with the first limiting plate 1015 and disposed parallel to the operation plate 1021, and the first limiting plate 1015 is fixed on the operation plate 1021 by fixing the mounting plate on the operation table. Similarly, the second limiting plate 1016 is secured in the same manner as the first limiting plate.

In this embodiment, the other end of the push rod 1014 has a fixing member 1017 having a cross section larger than that of the push rod 1014, and the fixing member 1017 has a thickness along the moving direction of the vacuum cylinder 1011. And the first and second limiting plates 1015 and 1016 have a gap therebetween, which is equal to the thickness of the fixing member 1017. The first limiting plate 1015 has a groove 1022 formed thereon, and the opening direction of the groove may be upward, downward, leftward or rightward, so long as the push rod is inserted into the groove. In the solution of the present embodiment, the opening direction of the groove is upward, and the push rod 1014 is inserted into the groove 1022 to fix the fixing component 1017 in the gap between the first limiting plate 1015 and the second limiting plate 1016.

The solution of this embodiment further includes that the reagent picking and placing device 100 further includes: the fixed plate 1018 has at least one holder 1019 for mounting the vacuum cylinder 1011 thereon.

The reagent dispensing device 100 further includes:

The reagent dispensing device 100 further includes a fixing plate 1018, and at least one holder 1019 for mounting the vacuum cylinder 1011 is provided on the fixing plate 1018. In use, a user fixes a desired number of vacuum cylinders 1011 on the cassette 1019 as desired. Of course, how many clamping seats 1019 are provided on the fixing plate 1018, and a corresponding number of upward opening grooves 1022 are provided on the first limiting plate 1015.

The reagent dispensing device 100 further comprises a slider and a drive screw 1013. One end of the transmission screw 1013 is connected with the driving device 1012, and driven by the driving device to rotate, and the other end of the transmission screw 1013 is inserted into the slider and is in transmission connection with the slider. Meanwhile, the sliding block is also connected with the fixed plate. When the vacuum cylinder fixing device is used, the driving device 1012 drives the transmission screw 1013 to rotate, the transmission screw only rotates without changing the position of the transmission screw, and the sliding block moves along the transmission screw along with the rotation of the transmission screw, so that the fixing plate is driven to move, and meanwhile, the vacuum cylinder on the fixing plate is also driven to move. The driving device makes the vacuumizing cylinder on the fixed plate reciprocate to control the air pressure change in the reagent accommodating tube connected with the vacuumizing cylinder 1011, thereby realizing the taking and placing of the reagent.

In the solution of this embodiment, since a plurality of sets of vacuum-pumping devices are provided, a number of reagent-containing devices corresponding to the vacuum-pumping devices are also provided. Therefore, when in use, the taking and placing of multiple groups of reagents can be realized at one time. The scheme further increases the taking and placing efficiency of the reagent.

As shown in fig. 4, in a further aspect of this embodiment, the reagent picking and placing device further includes:

a reagent holding apparatus 110 including a reagent holding tube 1101 for holding a reagent;

a first support frame 1102 for fixing the reagent holding tube 1101;

the moving mechanism is used for driving the first supporting frame 1102 to move.

The reagent taking and placing device provided by the embodiment comprises a reagent accommodating device 110 for storing a reagent, and a vacuumizing device connected with the reagent accommodating device 110, wherein the vacuumizing device enables a vacuum cylinder and a piston assembly to move relatively, so that the pressure in the reagent accommodating device 110 communicated with the vacuumizing device is reduced or increased, and the reagent is sucked into the reagent accommodating device 110 or is put out from the accommodating device. Wherein the reagent holding device 110 comprises a reagent holding tube 1101 for holding a reagent.

The reagent picking and placing device further comprises a first supporting frame 1102 for fixing the reagent holding tube 1101, and a moving mechanism for driving the first supporting frame 1102 to move. When in use, the moving mechanism is controlled to move the first supporting frame 1102 to the position of the reagent, the vacuumizing device is controlled to suck air to reduce the pressure in the reagent holding tube 1101, and the reagent is sucked into the reagent holding tube 1101; then, the moving mechanism is controlled to move continuously, the first supporting frame 1102 is moved to a region where reagent is required to be put in, and the vacuumizing device is controlled to be ventilated and pressurized so that the pressure in the reagent accommodating tube 1101 is increased, and reagent is put in.

The scheme of the embodiment further comprises: the first support frame 1102 includes a horizontally disposed plate-like structure provided with fixing holes in which the reagent holding tubes 1101 are inserted.

The first support frame 1102 provided in this embodiment includes a horizontally disposed plate-like structure provided with fixing holes for inserting and fixing the reagent holding tubes 1101.

In a further aspect of this embodiment, a plurality of fixing holes for fixing the reagent holding tube 1101 are provided on the plate-like structure. Specifically, the number of the fixing holes is consistent with the number of the vacuum cylinders of the vacuumizing device.

In a further version of this embodiment, at least one edge of the plate-like structure is provided with an upward or downward turned-up edge, thereby making the reagent holding tube 1101 more stable during movement.

The scheme of the embodiment further comprises: the reagent holding apparatus 110 further comprises a needle 1105 for sucking/dispensing the reagent;

the needle 1105 is connected to the lower end opening of the reagent holding tube 1101 through the second communication tube 1104.

The reagent picking and placing device further comprises: a needle 1105 for aspirating/dispensing the reagent. The needle 1105 is made of a metal material, and one end of the needle 1105 is downward, and the other end is connected to the lower end opening of the reagent holding tube 1101 through the second communication tube 1104. In the solution of the present embodiment, the second communication pipe 1104 is a rubber hose. It should be noted that, in the solution provided in this embodiment, a plurality of needles 1105 are provided, and the number of needles 1105 is identical to the number of fixing holes for installing the reagent holding tube 1101.

The reagent picking and placing device further comprises: a second support 1103 for securing the needle 1105.

Specifically, the second support frame 1103 includes a first support plate and a second support plate;

the first supporting plate is vertically arranged; the second supporting plate is formed by bending a plate-shaped structure and comprises a first part and a second part; wherein the first portion is perpendicular to the first support plate and the second portion is parallel to the first support plate;

the first support plate and the second portion are fixedly connected, and the needle 1105 is fixed by pressing the first support plate and the first portion against each other.

The following describes the above scheme in detail:

the second support frame 1103 includes a first support plate and a second support plate. The direction of the first support plate is parallel to the direction of the reagent holding tube 1101, that is, the first support plate is disposed in the vertical direction. The second supporting plate is formed by bending a metal plate-shaped structure, and the bending angle is ninety degrees. The second support plate includes a first portion perpendicular to the first support plate and a second portion parallel to the first support plate. The first support plate and the second support plate are provided with fixing holes, the needle 1105 is arranged between the first support plate and the first support plate, and the screw rod sequentially penetrates through the fixing holes in the second support plate and the first support plate to fix the needle 1105 on the second support frame 1103. In order to secure the needle 1105, a securing hole in the second portion is provided near the first portion.

In a further version of this embodiment, the area of the needle 1105 in contact with the first support plate and the second portion is provided with a protective structure. Since the needle 1105, the first support plate and the second support plate are all metal members in this embodiment, in order to fix the needle 1105 more stably between the first support plate and the second support plate, a protective structure is provided on the outer periphery of the needle 1105, and the protective structure may be a flexible material having a shape-variable or a material capable of fixing the needle 1105 more firmly, such as an adhesive tape.

In this embodiment, the driving device drives the vacuumizing device to enable the vacuum cylinder and the piston assembly to move relatively, and air pressure in the reagent accommodating device is changed, so that reagent extraction or delivery is achieved. The scheme is simple to operate, and the reagent taking and placing efficiency is high.

Example two

The embodiment provides a cell enrichment dyeing integrated device.

The integrated device provided in this embodiment includes the reagent picking and placing device described in the above embodiment. The reagent taking and placing device is used for adding the required reagent into the corresponding device in the process of enriching cells and the process of staining cells. The scheme is simple to operate and high in reagent taking and placing efficiency.

The foregoing description is only illustrative of the preferred embodiment of the present utility model, and is not to be construed as limiting the utility model, but is to be construed as limiting the utility model to any and all simple modifications, equivalent variations and adaptations of the embodiments described above, which are within the scope of the utility model, may be made by those skilled in the art without departing from the scope of the utility model.

Claims

1. A reagent pick-and-place device, comprising:

reagent holding means for holding a reagent;

2. The reagent dispensing device of claim 1, wherein the piston assembly comprises a piston and a push rod, one end of the push rod being fixedly connected to the piston;

3. A reagent dispensing device according to claim 2, wherein the evacuating means further comprises:

4. A reagent picking and placing device according to claim 3, wherein the limiting member comprises a first limiting plate arranged perpendicularly to the moving direction of the vacuum cylinder;

the other end of the push rod is fixed on the first limiting plate.

5. A reagent picking and placing device according to claim 3, wherein the limiting member comprises a first limiting plate and a second limiting plate which are arranged perpendicularly to the moving direction of the vacuum cylinder;

a gap is formed between the first limiting plate and the second limiting plate;

the first limiting plate is provided with a groove;

6. A reagent dispensing device according to any one of claims 1 to 5, further comprising a fixing plate on which at least one cartridge for mounting the vacuum cartridge is provided.

7. A reagent dispensing device according to claim 6, wherein,

the reagent picking and placing device further comprises:

8. A reagent dispensing device according to any one of claims 1 to 5, wherein the vacuum cartridge is connected to the reagent holding device by a first communication tube.

9. The reagent dispensing device of claim 8, wherein the vacuum means is disposed above and below the reagent receiving means;

10. A cell enrichment and staining integrated device, characterized in that the cell enrichment and staining integrated device comprises a reagent taking and placing device according to any one of claims 1 to 9.