CN220564640U - 基于反应器的细胞培养系统 - Google Patents
基于反应器的细胞培养系统 Download PDFInfo
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- CN220564640U CN220564640U CN202321969622.6U CN202321969622U CN220564640U CN 220564640 U CN220564640 U CN 220564640U CN 202321969622 U CN202321969622 U CN 202321969622U CN 220564640 U CN220564640 U CN 220564640U
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- hollow fiber
- reactor
- bioreactor
- bottle
- cell culture
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- 238000004113 cell culture Methods 0.000 title claims abstract description 28
- 239000012510 hollow fiber Substances 0.000 claims abstract description 70
- 239000007788 liquid Substances 0.000 claims abstract description 55
- 239000012528 membrane Substances 0.000 claims abstract description 29
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 17
- 238000011081 inoculation Methods 0.000 claims abstract description 8
- 239000006052 feed supplement Substances 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract description 7
- 239000001301 oxygen Substances 0.000 abstract description 7
- 229910052760 oxygen Inorganic materials 0.000 abstract description 7
- 230000010261 cell growth Effects 0.000 abstract description 6
- 230000001502 supplementing effect Effects 0.000 abstract description 2
- 239000000243 solution Substances 0.000 description 29
- 239000007789 gas Substances 0.000 description 11
- 238000000034 method Methods 0.000 description 6
- 230000010412 perfusion Effects 0.000 description 6
- 238000007599 discharging Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 230000012010 growth Effects 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 3
- 238000005273 aeration Methods 0.000 description 3
- 239000012091 fetal bovine serum Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 239000002504 physiological saline solution Substances 0.000 description 3
- -1 polypropylene Polymers 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 239000000523 sample Substances 0.000 description 3
- 238000005070 sampling Methods 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 238000009423 ventilation Methods 0.000 description 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 241001125929 Trisopterus luscus Species 0.000 description 2
- 238000009833 condensation Methods 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 238000004886 process control Methods 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000003501 co-culture Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000002900 effect on cell Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000012787 harvest procedure Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920002239 polyacrylonitrile Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000013102 re-test Methods 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202321969622.6U CN220564640U (zh) | 2023-07-25 | 2023-07-25 | 基于反应器的细胞培养系统 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202321969622.6U CN220564640U (zh) | 2023-07-25 | 2023-07-25 | 基于反应器的细胞培养系统 |
Publications (1)
Publication Number | Publication Date |
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CN220564640U true CN220564640U (zh) | 2024-03-08 |
Family
ID=90102125
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN202321969622.6U Active CN220564640U (zh) | 2023-07-25 | 2023-07-25 | 基于反应器的细胞培养系统 |
Country Status (1)
Country | Link |
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CN (1) | CN220564640U (zh) |
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2023
- 2023-07-25 CN CN202321969622.6U patent/CN220564640U/zh active Active
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TR01 | Transfer of patent right |
Effective date of registration: 20240418 Address after: 430000, West C308, Building C4, Biological Innovation Park, No. 666 Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan City, Hubei Province Patentee after: Wuhan Tonggan Medical Technology Co.,Ltd. Country or region after: China Address before: 430000 No. 818, Gaoxin Avenue, Donghu high tech Development Zone, Hongshan District, Wuhan City, Hubei Province Patentee before: WUHAN TOGO MEDITECH Co.,Ltd. Country or region before: China |