CN220448549U - Micro-fluidic chip packaging device - Google Patents
Micro-fluidic chip packaging device Download PDFInfo
- Publication number
- CN220448549U CN220448549U CN202321499732.0U CN202321499732U CN220448549U CN 220448549 U CN220448549 U CN 220448549U CN 202321499732 U CN202321499732 U CN 202321499732U CN 220448549 U CN220448549 U CN 220448549U
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- Prior art keywords
- inlet end
- chip packaging
- auxiliary
- microfluidic chip
- entrance point
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- 238000004806 packaging method and process Methods 0.000 title claims abstract description 25
- 238000007789 sealing Methods 0.000 claims abstract description 37
- 239000007788 liquid Substances 0.000 claims description 19
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 6
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 6
- 241001330002 Bambuseae Species 0.000 claims description 6
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 6
- 239000011425 bamboo Substances 0.000 claims description 6
- 238000003825 pressing Methods 0.000 claims description 6
- 230000003014 reinforcing effect Effects 0.000 claims description 6
- 238000007599 discharging Methods 0.000 claims description 5
- 206010066054 Dysmorphism Diseases 0.000 claims description 4
- 125000003003 spiro group Chemical group 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 11
- 238000010030 laminating Methods 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 8
- 238000005457 optimization Methods 0.000 description 6
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 239000012528 membrane Substances 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000012491 analyte Substances 0.000 description 3
- 238000001514 detection method Methods 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000008073 immune recognition Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
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- Sampling And Sample Adjustment (AREA)
Abstract
The utility model discloses a microfluidic chip packaging device, which belongs to the technical field of medical appliances, and adopts the technical scheme that the microfluidic chip packaging device comprises an inlet end, an outlet end which is in threaded connection with the bottom of the inlet end and a discharge hole which is arranged in the outlet end, wherein an auxiliary component is arranged between the inlet end and the outlet end; the top thread is arranged in the sleeve barrel, the sealing gasket is arranged at the bottom of the sleeve barrel, the special-shaped groove is arranged at the top of the sealing gasket, the sealing assembly seals the top of the inlet end by arranging the sealing assembly and the auxiliary assembly, and the top of the inlet end is in various contact with the sealing assembly when the top of the inlet end is sealed, increase the contact surface, reduce the possibility of leaking, carry out auxiliary seal through auxiliary assembly between to exit end and the entrance point, and the bottom of entrance point and the laminating of the top of exit end constitute auxiliary seal's effect between auxiliary assembly and, entrance point and the exit end, and along with screwing up between entrance point and the exit end, the effect is better.
Description
Technical Field
The utility model relates to the technical field of medical appliances, in particular to a microfluidic chip packaging device.
Background
At present, the detection of some target cells such as circulating brain tumor cells mainly captures the target cells through a filter membrane according to different cell sizes or an immune recognition enrichment method, and in the process of capturing and detecting the analyte in a sample by utilizing a microfluidic chip, the steps of specifically capturing the analyte, removing interfering substances, marking the analyte, performing qualitative/quantitative analysis and the like are required, and the porous filter membrane method has the following defects: 1. the pore diameter is single, is not consistent with the cell size diversity of the actual clinical patients, and has the omission phenomenon; 2. the reagent consumption is large, and the later characterization is not easy to carry out; 3. blocking phenomenon is easy to occur, and the detection result is influenced; 4. the special filter preparation process is complex and has high cost.
The current announcements are: the utility model discloses a micro-fluidic chip packaging device, which comprises an inlet end, an outlet end and a sealing end arranged between the inlet end and the outlet end, wherein a sample cavity penetrating through the inlet end in the length direction is formed in the inlet end, an upper connecting part used for being connected with the outlet end is arranged at the lower part of the inlet end, the outlet end comprises a lower connecting part used for being connected with the upper connecting part and a sample outlet pipe used for discharging samples, a sample outlet used for being communicated with the sample cavity is formed in the sample outlet pipe, a chip cavity used for containing the micro-fluidic chip is formed in the sealing end, the upper part of the chip cavity is communicated with the sample cavity, and the lower part of the chip cavity is communicated with the sample outlet.
Although this patent is through encapsulating micro-fluidic chip in sealed end to with sealed end and entrance point detachably connect, encapsulation process is simple, and can directly detect and survey after directly dismantling the exit end, has reduced the risk that personnel contacted with biological sample, but this patent does not have relevant sealing device when the top of entrance point is connected when connecting, leads to the problem that the membrane liquid leaked easily when making the chip coating film.
Disclosure of Invention
1. Technical problem to be solved
The utility model provides a microfluidic chip packaging device, and aims to solve the problem that the top of an inlet end of the conventional microfluidic chip packaging device is not provided with a relevant sealing device when being connected, so that film liquid is easy to leak when a chip is coated.
2. Technical proposal
The utility model is realized in such a way that the microfluidic chip packaging device comprises an inlet end, an outlet end which is in threaded connection with the bottom of the inlet end and a discharge hole which is arranged in the outlet end, wherein a sealing component is arranged in the top of the inlet end, and an auxiliary component is arranged between the inlet end and the outlet end;
the sealing assembly comprises a sleeve barrel, a top thread, a sealing gasket and a special-shaped groove, wherein the sleeve barrel is arranged on the outer side of the top of the inlet end, the top thread is arranged in the sleeve barrel, the sealing gasket is arranged at the bottom of the sleeve barrel, and the special-shaped groove is arranged at the top of the sealing gasket.
In order to increase the sealing effect between the outlet end and the inlet end, as a preferable microfluidic chip packaging device of the present utility model, the auxiliary assembly includes a protrusion portion and an auxiliary pad, the protrusion portion is disposed at the top of the outlet end and is clamped to the inlet end, and the auxiliary pad is adhered to the bottom of the inlet end and is clamped to the protrusion portion.
In order to make the superfluous membrane liquid flow out from the curved surface more conveniently, as a preferable micro-fluidic chip packaging device of the utility model, the top of the discharging hole is provided with a curved surface part for concentrating the liquid flow.
In order to achieve the effect of unscrewing the outlet port, it is preferable that a microfluidic chip packaging apparatus of the present utility model is provided with a cleat for screwing the outlet port on the outside of the outlet port.
In order to increase the strength of the inlet end, a microfluidic chip packaging apparatus according to the present utility model is preferably provided with reinforcing ribs on the side of the inlet end.
In order to increase the effect of auxiliary sealing between the inlet end and the outlet end, as a microfluidic chip packaging apparatus of the present utility model, preferably, the top of the protruding portion is provided with a pressing pad.
In order to provide an anti-slip effect when the side surface of the inlet end is held, the side surface of the inlet end is preferably provided with an anti-slip part as a microfluidic chip packaging device of the present utility model.
3. Advantageous effects
Compared with the prior art, the utility model has the beneficial effects that:
this micro-fluidic chip packaging device, through setting up seal assembly and auxiliary assembly, seal assembly makes the top of entrance point sealed, and the top of entrance point is when sealed, the top of entrance point and seal assembly contact variously, increase the contact surface, reduce the possibility of leaking, carry out auxiliary seal through auxiliary assembly between exit point and the entrance point, and the bottom of entrance point and the laminating of the top of exit point, auxiliary assembly and, constitute auxiliary seal's effect between entrance point and the exit point, and along with screwing up between entrance point and the exit point, the effect is better.
Drawings
FIG. 1 is an overall block diagram of the present utility model;
FIG. 2 is a schematic view in left side perspective cross section of the present utility model;
FIG. 3 is a schematic view of a seal assembly of the present utility model;
FIG. 4 is a schematic view of an auxiliary assembly of the present utility model;
FIG. 5 is a schematic view of a gasket and a profiled groove of the present utility model.
The reference numerals in the figures illustrate:
1. an inlet end; 2. an outlet end; 3. a seal assembly; 4. an auxiliary component; 5. a discharge hole; 6. a curved surface portion; 7. a cleat; 8. reinforcing ribs; 9. pressing the pad; 10. an anti-slip part; 301. the cylinder is sleeved; 302. a top thread; 303. a sealing gasket; 304. a special-shaped groove; 401. a boss; 402. an auxiliary pad.
Detailed Description
The present utility model will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present utility model more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the utility model.
In the description of the present utility model, it should be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate orientations or positional relationships based on the orientation or positional relationships shown in the drawings, merely to facilitate describing the present utility model and simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present utility model. Furthermore, in the description of the present utility model, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
Referring to fig. 1-5, the present utility model provides the following technical solutions: the microfluidic chip packaging device comprises an inlet end 1, an outlet end 2 screwed at the bottom of the inlet end 1 and a discharge hole 5 formed in the outlet end 2, wherein a sealing component 3 is arranged in the top of the inlet end 1, and an auxiliary component 4 is arranged between the inlet end 1 and the outlet end 2;
the sealing assembly 3 comprises a sleeve 301, a top thread 302, a sealing gasket 303 and a special-shaped groove 304, wherein the sleeve 301 is arranged on the outer side of the top of the inlet end 1, the top thread 302 is arranged in the sleeve 301, the sealing gasket 303 is arranged at the bottom of the sleeve 301, and the special-shaped groove 304 is arranged at the top of the sealing gasket 303.
In this embodiment: by arranging the sealing component 3 and the auxiliary component 4, the sealing component 3 seals the top of the inlet end 1, the top of the inlet end 1 is in various contact with the sealing component 3 when in sealing, the contact surface is increased, the possibility of leakage is reduced, the auxiliary sealing is carried out between the outlet end 2 and the inlet end 1 through the auxiliary component 4, the bottom of the inlet end 1 is attached to the top of the outlet end 2, the auxiliary component 4 and the inlet end 1 and the outlet end 2 form an auxiliary sealing effect, and the effect is better along with tightening between the inlet end 1 and the outlet end 2;
through setting up cover section of thick bamboo 301, top screw thread 302, sealing washer 303 and dysmorphism groove 304, when cover section of thick bamboo 301 and the notes liquid pipe connection that is used for the encapsulation, notes liquid pipe and top screw thread 302 are connected, contact through sealing washer 303 and notes liquid pipe, and the notes liquid pipe supports sealing washer 303, and dysmorphism groove 304 then makes the irregular arch on sealing washer 303 surface provide the deformation space.
As a technical optimization scheme of the utility model, the auxiliary assembly 4 comprises a protruding portion 401 and an auxiliary pad 402, wherein the protruding portion 401 is arranged at the top of the outlet end 2 and is clamped at the inlet end 1, and the auxiliary pad 402 is adhered to the bottom of the inlet end 1 and is clamped at the protruding portion 401.
In this embodiment: through setting up bellying 401 and auxiliary pad 402, bellying 401 and the joint of entrance point 1, auxiliary pad 402 and bellying 401 shape block, auxiliary pad 402 and bellying 401 prevent the membrane liquid from flowing out between entrance point 1 and the exit end 2 this moment.
As a technical optimization scheme of the utility model, the top of the discharging hole 5 is provided with a curved surface part 6 for centralizing liquid flow.
In this embodiment: by providing the curved surface portion 6, the surplus film liquid can be discharged from the discharge hole 5.
As a technical optimization scheme of the utility model, the outside of the outlet end 2 is provided with a antiskid plate 7 for screwing the outlet end 2.
In this embodiment: the top of the outlet end 2 is made antiskid by providing antiskid plates 7.
As a technical optimization scheme of the utility model, the side face of the inlet end 1 is provided with a reinforcing rib 8.
In this embodiment: the bottom of the inlet end 1 is reinforced and not easy to bend by the reinforcing ribs 8.
As a technical optimization of the present utility model, the top of the boss 401 is provided with the pressing pad 9.
In this embodiment: the top of the boss 401 is sealed with the aid of the pressing pad 9.
As a technical optimization of the present utility model, the side surface of the inlet end 1 is provided with an anti-slip part 10.
In this embodiment: the side surface of the inlet end 1 is lifted up by the anti-skid part 10, so that the inlet end is not easy to slide by hands.
Working principle: first, when the cylinder 301 is sleeved and connected with the liquid injection pipe for packaging, the liquid injection pipe is connected with the top thread 302, the liquid injection pipe is connected with the liquid injection pipe through the sealing gasket 303, the liquid injection pipe is propped against the sealing gasket 303, the irregular protrusions on the surface of the sealing gasket 303 are provided with deformation spaces by the special-shaped grooves 304, the protrusions 401 are clamped with the inlet end 1, the auxiliary gasket 402 is clamped with the protrusions 401, at the moment, the auxiliary gasket 402 and the protrusions 401 prevent film liquid from flowing out from the position between the inlet end 1 and the outlet end 2, the excessive film liquid can flow out of the discharging hole 5 through the arrangement of the curved surface part 6, the top of the outlet end 2 is anti-skid through the arrangement of the anti-skid plate 7, the bottom of the inlet end 1 is reinforced and is not easy to bend through the arrangement of the reinforcing ribs 8, the top of the protrusions 401 is provided for auxiliary sealing through the arrangement of the pressing gasket 9, and the side surface of the inlet end 1 is taken up and is not easy to slide by hand through the arrangement of the anti-skid part 10.
The foregoing description of the preferred embodiments of the utility model is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the utility model.
Claims (7)
1. The utility model provides a micro-fluidic chip packaging hardware, includes entrance point (1), spiro union in exit end (2) of entrance point (1) bottom and offer in inside discharge opening (5) of exit end (2), its characterized in that: a sealing component (3) is arranged in the top of the inlet end (1), and an auxiliary component (4) is arranged between the inlet end (1) and the outlet end (2);
seal assembly (3) are including covering section of thick bamboo (301), top screw thread (302), sealed pad (303) and dysmorphism groove (304), it sets up in the outside at entrance point (1) top to cover section of thick bamboo (301), top screw thread (302) are seted up in the inside of covering section of thick bamboo (301), sealed pad (303) are placed in the bottom of covering section of thick bamboo (301), dysmorphism groove (304) are seted up in the top of sealed pad (303).
2. The microfluidic chip packaging apparatus according to claim 1, wherein: the auxiliary assembly (4) comprises a protruding portion (401) and an auxiliary pad (402), the protruding portion (401) is arranged at the top of the outlet end (2) and is clamped at the inlet end (1), and the auxiliary pad (402) is adhered to the bottom of the inlet end (1) and is clamped at the protruding portion (401).
3. The microfluidic chip packaging apparatus according to claim 1, wherein: the top of the discharging hole (5) is provided with a curved surface part (6) for concentrating liquid flow.
4. The microfluidic chip packaging apparatus according to claim 1, wherein: the outside of the outlet end (2) is provided with a antiskid plate (7) for screwing the outlet end (2).
5. The microfluidic chip packaging apparatus according to claim 1, wherein: the side of the inlet end (1) is provided with a reinforcing rib (8).
6. The microfluidic chip packaging apparatus according to claim 2, wherein: the top of the protruding part (401) is provided with a pressing pad (9).
7. The microfluidic chip packaging apparatus according to claim 1, wherein: the side of the inlet end (1) is provided with an anti-skid part (10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321499732.0U CN220448549U (en) | 2023-06-13 | 2023-06-13 | Micro-fluidic chip packaging device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321499732.0U CN220448549U (en) | 2023-06-13 | 2023-06-13 | Micro-fluidic chip packaging device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220448549U true CN220448549U (en) | 2024-02-06 |
Family
ID=89723980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321499732.0U Active CN220448549U (en) | 2023-06-13 | 2023-06-13 | Micro-fluidic chip packaging device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220448549U (en) |
-
2023
- 2023-06-13 CN CN202321499732.0U patent/CN220448549U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant |