CN220424612U - Deoxidizing device for surfactant solution - Google Patents

Abstract

The utility model relates to the field of medicine production equipment, and discloses a deoxidizing device for surfactant solution, which comprises an operation tank, a storage tank, a transmission pipeline and a transmission pump; the top of the operating tank is provided with a vacuumizing-nitrogen charging pipeline component A; the storage tank is provided with a vacuumizing-nitrogen charging pipeline component B, the tank walls of the operation tank and the storage tank are respectively provided with a heat exchange jacket, and the tank bottom is respectively provided with an eccentric double-layer paddle stirrer. The device can treat the deoxidization of the surfactant solution in a large scale (50L), especially can treat the deoxidization of the surfactant solution with high viscosity (more than 10 mPa.s), can realize the stable control of the target limit of dissolved oxygen below 2ppm, ideally realize the stable control of the target limit below 1ppm, and meet the requirement of the industrialized mass preparation of medicines.

Description

Deoxidizing device for surfactant solution

Technical Field

The utility model relates to the field of medicine production equipment, in particular to a deoxidizing device for surfactant solution.

Background

The surfactant is used as a common auxiliary material in the medical field, and dissolved oxygen in the prepared surfactant-containing solution is easy to cause oxidative degradation of the medical preparation, and particularly the stability of the injection is obviously influenced, so that the dissolved oxygen of the surfactant solution is usually required to be controlled below 2ppm in the medical field. The current methods for controlling the dissolved oxygen mainly comprise a vacuum method and a nitrogen blowing method. Wherein, the vacuum method is to reduce the dissolved oxygen in the solution by repeatedly vacuumizing and filling nitrogen into the solution preparation tank; the nitrogen blowing method is to introduce high-purity nitrogen below the liquid surface of the solution to replace oxygen in the solution so as to reduce the dissolved oxygen in the solution.

Compared with the traditional vacuum method, the nitrogen blowing method is more effective for controlling the dissolved oxygen in the solution, and can control the dissolved oxygen in the solution within 2 ppm; however, if high-purity nitrogen is introduced into a solution containing a surfactant under the liquid surface by nitrogen blowing, a large number of bubbles which are difficult to remove later cannot be avoided even if the flow rate of the nitrogen is controlled at an extremely low level, the bubbles usually fill the liquid preparation tank within a few minutes, and after the bubbles fill the liquid preparation tank, the dissolved oxygen in the solution cannot be further reduced by continuing to introduce nitrogen. Therefore, the nitrogen blowing method is inferior to the vacuum method for controlling the dissolved oxygen of the surfactant solution. However, the vacuum method has limitations that the residual oxygen in the headspace needs to be controlled within 2%, which requires the vacuum degree to be at least reduced to within-0.9 bar, and the performance requirement on a vacuum pump is higher; at the same time, for the treatment of a large amount of solution, such as the solution volume exceeds 10L, further exceeds 100L, longer time (for example, single vacuum holding time exceeds 1 h) and more times of vacuumizing-nitrogen filling are usually up to several hours, and the vacuumizing-nitrogen filling is repeated for more than 5 times. Therefore, the existing vacuum method has the main disadvantages that: (1) the extremely low vacuum degree brings extremely high requirements on vacuum-nitrogen charging equipment, and potential safety hazards are easy to generate; (2) only small batch processing can be realized, for large batch processing, the deoxidizing efficiency is obviously reduced, dissolved oxygen can not be stably controlled below the target limit, the time consumption is extremely long, the equipment burden is heavy, the energy consumption is large, and the requirement of industrial production can not be met.

In addition, patent CN 101563057B discloses that the dissolved oxygen concentration of the feed liquid preparation can be within 2ppm by adopting a sterilizing and deoxidizing device at 100-121 ℃. However, this technique is not suitable for high volume surfactant solution treatment because surfactant solutions tend to have low boiling points, high Wen Yifa are subject to degradation, and too high temperatures can also present safety concerns. Both patent CN111812969 a and patent CN 113772772A disclose the use of special dissolved oxygen control devices to control dissolved oxygen, however these devices are not only expensive to manufacture, but also do not have general applicability.

In summary, treating dissolved oxygen below target limits for large volumes of surfactant solutions (especially high viscosity surfactant solutions) is a great challenge for current dissolved oxygen control methods. The prior art can not meet the requirement of mass industrialized preparation, and particularly relates to the requirement of industrialized preparation of medical injection.

Disclosure of Invention

In order to solve the technical problems, the utility model provides a deoxidizing device for a surfactant solution. The device can treat the deoxidization of the surfactant solution in a large scale (50L), especially the deoxidization of the surfactant solution with high viscosity (more than 10 mPa.s), can realize the stable control of the target limit of dissolved oxygen below 2ppm, and meets the requirement of the industrialized mass preparation of medicines.

The specific technical scheme of the utility model is as follows: a deoxidizing device for surfactant solution, comprising an operation tank, a storage tank, a transmission pipeline and a transmission pump; two ends of the transmission pipeline are respectively communicated with the bottom of the operation tank and the side wall of the storage tank; the transmission pump is arranged on the transmission pipeline.

The tank top or the tank wall of the operation tank is provided with a charging port, and the tank top is provided with a vacuumizing-nitrogen charging pipeline component A.

The vacuumizing-nitrogen charging pipeline assembly A comprises a nitrogen charging branch pipe, a vacuumizing branch pipe, a main pipeline and a vacuumizing-nitrogen charging head; the main pipeline penetrates into the operation tank; the nitrogen charging branch pipe and the vacuumizing branch pipe are respectively connected with the outer end of the tank of the main pipeline, and the vacuumizing-nitrogen charging head is arranged at the inner end of the tank of the main pipeline.

The vacuumizing-nitrogen filling head comprises an outer pipe and an inner pipe, a gap is arranged between the outer pipe and the inner pipe, the top and the bottom of the inner pipe are lower than the top and the bottom of the outer pipe, and the bottom of the outer pipe is sealed with the outer wall of the inner pipe; the top of the outer tube is provided with a sealing ring which can move up and down along the inner wall of the outer tube, and the outer diameter and the inner diameter of the sealing ring are respectively matched with the inner diameter of the top of the outer tube and the outer diameter of the top of the inner tube.

The outer tube inner wall is located the below of sealing washer and is equipped with the stopper, and the stopper is less than the inner tube top, and the outer tube lateral wall is located the stopper below and is equipped with the air vent.

The storage tank is provided with a vacuumizing-nitrogen charging pipeline component B, the tank walls of the operation tank and the storage tank are respectively provided with a heat exchange jacket, and the tank bottom is respectively provided with an eccentric double-layer paddle stirrer.

The utility model mainly comprises an operation tank and a storage tank which are connected in series, wherein the operation tank is mainly responsible for carrying out vacuum-nitrogen charging treatment on the surfactant solution to reduce the dissolved oxygen content, the storage tank is mainly used for storing the deoxidized surfactant solution, and the operation tank is mainly responsible for deoxidizing the surfactant solution. The device of the utility model has the following characteristics:

(1) In the prior art, an independent nitrogen filling pipeline and a vacuum pumping pipeline are respectively arranged at the top of a tank body, and the vacuum pumping-nitrogen filling pipeline assembly A integrates the two pipelines into a whole, and the working principle is as follows:

in the vacuumizing mode, the sealing ring is displaced to the top of the outer tube (i.e. is not contacted with the inner tube) under the pressure effect, and gas in the tank body enters from the air vent of the side wall of the outer tube and flows upwards, and is continuously discharged from the vacuumizing branch tube after passing through the middle hole of the sealing ring. Under the nitrogen filling mode, the sealing ring is pressed down to the limiting block by nitrogen, at the moment, the middle hole of the sealing ring is filled by the top of the inner pipe and forms sealing, and the outer wall of the sealing ring and the inner wall of the outer pipe form sealing, so that nitrogen can only enter from the opening at the top of the inner pipe and enter the tank. The advantages of the above structure are: (1) the multi-pipeline design can challenge the tightness of the tank body and influence the gas replacement effect, and the vacuumizing-nitrogen charging pipeline assembly A only has one opening on the tank body, so that the tightness is better; (2) because the density of oxygen in the air is greater than that of nitrogen, the pipe orifice of the vacuumizing and nitrogen charging pipeline is as close to the liquid level as possible, and when the vacuumizing and nitrogen charging pipeline assembly A performs nitrogen charging operation, the nitrogen is opposite to the vortex formed when the feed liquid is stirred from the inner pipe at a high flow rate, so that the oxygen in the vortex can be more effectively replaced, and the effect of reducing the dissolved oxygen can be further effectively achieved.

(2) The utility model adopts a double-layer paddle stirrer and is fixed at the bottom of the tank in an eccentric mode. Firstly, the double-layer paddle stirrer is fixed at the bottom of the tank in an eccentric mode (namely, not positioned on the central shaft of the tank body), has weak shearing action, is favorable for reducing the viscosity of the solution, can inhibit or crush bubbles in the surfactant solution while stirring to form a vortex penetrating through the solution, and simultaneously increases the internal mixing of the feed liquid and obviously improves the deoxidizing efficiency. Secondly, the double-layer paddle stirrer is designed by the upper and lower double-layer paddles, the double-layer paddles are favorable for forming vortexes penetrating through the feed liquid, and meanwhile, the stirring head has a weak shearing effect on the feed liquid due to the design of the included angles between the upper and lower paddles and the axle center, so that the solution viscosity can be reduced, and the mixing effect can be improved especially for the feed liquid with the volume of more than 50L. Therefore, the setting mode of the double-layer paddle stirrer not only can effectively avoid the difficulty of processing high-viscosity solution by conventional bottom magnetic stirring, has overlarge resistance or is easy to generate bubbles, but also can effectively avoid the problem that the sealing performance of a stirring shaft cannot be solved by downward extending stirring at the top in a tank and the problem that the bubbles are easy to generate in the material liquid in the stirring process so as to be unfavorable for deoxidation.

(3) The outer wall of the tank body is provided with a heat exchange jacket, and a circulating heat exchange medium is communicated in the heat exchange jacket, so that the temperature of the solution in the tank can be regulated and controlled. Under the combined action of the heat exchange jacket and the stirrer, on one hand, the heat exchange between the feed liquid and the heat exchange jacket can be promoted, the temperature control of the feed liquid can be promoted to deoxidize, and meanwhile, the viscosity of the feed liquid can be regulated by the temperature control to promote deoxidization, and on the other hand, the contact area of the feed liquid and the headspace nitrogen can be increased to deoxidize. The deoxygenation efficiency is optimal when agitation creates a vortex throughout the feed liquid.

In summary, the integrated vacuumizing-nitrogen charging pipeline assembly A is arranged on the tank body, the heat jacket is replaced outside the tank wall, and the eccentric double-layer blade stirrer is arranged at the bottom of the tank, so that under the combined action of all the components, the deoxidization treatment of high-viscosity large-batch surfactant solution can be coped with, and the dissolved oxygen of the solution can be effectively reduced to the target limit.

Preferably, a filter is provided on the transmission line.

The filter is arranged between the operation tank and the storage tank, the heat exchange jacket of the operation tank controls the material temperature (20-60 ℃ and preferably 40-60 ℃ when high-viscosity feed liquid is processed), further pressure difference between the operation tank and a transmission pipeline can be formed through the vacuum environment of the storage tank and nitrogen supplementing in the operation tank in the filtering process, the moderate heat filtering sterilization of high-capacity high-viscosity materials is effectively promoted by combining the conveying power of the pump, and meanwhile, the filter has the effects of effectively inhibiting bubbles, crushing bubbles in surfactant solution and promoting deoxidization. The sterilization and deoxidation treatment conditions are mild, and the energy consumption is low. Effectively avoiding the defect that the high-viscosity solution in the prior art is often sterilized by high-temperature filtration above 100 ℃ and combined with a deoxidizing device. When the temperature is too high, the solution containing the surfactant has low boiling point and is easy to degrade, so that potential safety hazard is brought. When the temperature is too low, the dissolved oxygen is not reduced, and meanwhile, the temperature is too low, the viscosity of the solution is large, and the filtration is extremely difficult.

The utility model adopts non-pressurized delivery filtration, which is beneficial to improving the deoxidizing efficiency.

Further, the filter consists of a filter shell and a filter element, wherein the filter shell is made of stainless steel, the filter element can adopt a single-stage filter element or a two-stage filter element in series connection, and the filter element is made of PES, PVDF, PTFE, PP, nylon, glass fiber and the like, wherein hydrophilic PVDF and PTFE are preferable.

Preferably, the nitrogen charging direction of the vacuumizing-nitrogen charging pipeline assembly A faces to the double-layer blade stirrer.

Preferably, the horizontal distance between the double-layer paddle stirrer and the central shaft of the operation tank or the storage tank is 1/4-1/6 of the maximum inner diameter of the tank body of the operation tank or the storage tank.

Preferably, the upper layer blade and the lower layer blade of the double-layer blade stirrer are respectively composed of 2 blades; the upper layer blade and the stirring shaft form an included angle of 10-60 degrees, the lower layer blade and the stirring shaft form an included angle of 100-170 degrees, and the included angle of the upper layer blade and the lower layer blade under the overlooking angle is not less than 30 degrees.

Preferably, the double-layer paddle stirrer is detachably connected.

The detachable double-layer blade stirrer is convenient to clean or replace.

Preferably, the top or the side wall of the operation tank and the storage tank are provided with visual windows, and oxygen dissolving electrodes are arranged in the tank.

The dissolved oxygen electrode can monitor the dissolved oxygen content of the solution in the tank, and the visual window can be used for observing the liquid level in the tank during feeding and the vortex state of the solution during stirring.

Preferably, the transfer pump is selected from the group consisting of a diaphragm pump, peristaltic pump, plunger pump, rotor pump, gear pump. The peristaltic pump and the plunger pump can further avoid a large number of bubbles generated in the feed liquid in the transmission process, so that the filtering efficiency is improved, and meanwhile, the dissolved oxygen of the feed liquid is effectively kept at a lower level.

Preferably, the vacuumizing-nitrogen charging pipeline assembly B comprises a nitrogen charging branch pipe, a vacuumizing branch pipe and a general pipe; the universal pipe penetrates into the storage tank; the nitrogen-charging branch pipe and the vacuumizing branch pipe are respectively connected with one end of the universal pipe, which is positioned outside the tank.

It is further preferred that the universal pipe bottom is no more than 1/2 of the height in the tank from the tank bottom.

Preferably, valves are respectively arranged on the nitrogen charging branch pipe, the vacuumizing branch pipe, the nitrogen charging branch pipe and the vacuumizing branch pipe.

Preferably, an inner extension pipe connected with the transmission pipeline is arranged in the storage tank, the inner extension pipe extends to be close to the tank bottom along the inner side wall of the storage tank, and the distance between the bottom of the inner extension pipe and the tank bottom is not more than 50cm.

Different from the feed inlet setting of operation jar, the feed inlet setting of holding vessel is located on the jar body lateral wall and is connected along the inner wall to be close the tank bottoms with interior extension pipe. The advantage of this design is that feed liquid directly flows to the tank bottom along interior extension pipe and holding vessel inner wall, can not produce the bubble, avoids the feed liquid to fall into the tank bottom and forms a large amount of bubbles.

Compared with the prior art, the utility model has the beneficial effects that:

(1) The deoxidizing device comprises simple liquid preparation, filtration and collection steps, can inhibit the generation of bubbles in the solution, can efficiently treat the dissolved oxygen of the surfactant solution with the volume of more than 50L, is suitable for the efficient treatment of the surfactant solution with the viscosity of more than or equal to 10mPa.s, ideally realizes the control of the dissolved oxygen to below 2ppm, preferably realizes the control of the dissolved oxygen to below 1ppm, optimally realizes the control of the dissolved oxygen to below 0.5ppm, has good production reproducibility, stable quality among batches and saves the equipment cost and the production cost.

(2) The filter is arranged on the transmission pipeline between the operation tank and the storage tank, and the pressure difference between two ends of the filter can be adjusted through the operation tank and the storage tank, so that non-pressurized delivery filtration and deoxidation are realized. The direct filtration of high-viscosity solution is difficult, the high-temperature filtration is removed, the filtration is carried out conventionally through pressurization, but the deoxidation treatment of the solution is not facilitated under the pressurization condition, the filtration plays a role in sterilization, and the deoxidation effect is not ideal.

(3) By the deoxidizing device, the performance of the vacuum pump only needs to reach the vacuum degree of minus 0.6 to minus 0.8bar, the performance requirement on the vacuum pump is reduced, and the service life of the vacuum pump is prolonged.

(4) The extremely low dissolved oxygen solution treated by the utility model is used for a pharmaceutical preparation, can obviously improve the stability of oxygen sensitive drugs, and is convenient for the storage, transportation and clinical application of the drugs.

Drawings

FIG. 1 is a schematic view of a construction of the present utility model;

FIG. 2 is a schematic structural view of the vacuum pumping-nitrogen charging head in the vacuum pumping state;

FIG. 3 is a schematic view of the structure of the vacuum pumping-nitrogen charging head in the nitrogen charging state;

FIG. 4 is a schematic view of the seal ring of the vacuum pumping-nitrogen charging head of the present utility model;

FIG. 5 is a schematic view of the angle between the upper and lower paddles and the stirring shaft in the double-layer paddle stirrer of the utility model;

fig. 6 is a schematic view of the angle between upper and lower paddles in a double-layer paddle agitator of the utility model in a top view.

The reference numerals are: the device comprises an operation tank 1, a storage tank 2, a transmission pipeline 3, a filter 4, a transmission pump 5, a charging port 6, a heat exchange jacket 7, a double-layer blade stirrer 8, a nitrogen charging branch pipe 9, a vacuumizing branch pipe 10, a main pipeline 11, a vacuumizing-nitrogen charging head 12, a valve 13, an inner extension pipe 14, a nitrogen charging branch pipe 15, a vacuumizing branch pipe 16, a general pipe 17, an oxygen dissolving electrode 18, an upper-layer blade 81, a lower-layer blade 82, a stirring shaft 83, an outer pipe 121, an inner pipe 122, a sealing ring 123, a limiting block 124 and a vent 125.

Detailed Description

The utility model is further described below with reference to examples. The devices, connection structures and methods referred to in this utility model are those well known in the art, unless otherwise specified.

General examples

A deoxidizing device for surfactant solution, as shown in fig. 1, comprises an operation tank 1, a storage tank 2, a transmission pipeline 3, a filter 4 and a transmission pump 5; two ends of the transmission pipeline are respectively communicated with the bottom of the operation tank and the side wall of the storage tank; the filter and the transfer pump are arranged on the transfer pipeline. Specifically:

as shown in fig. 1, a charging port 6 is arranged on the tank top or the tank wall of the operation tank, a heat exchange jacket 7 is arranged on the tank wall of the operation tank, and a vacuumizing-nitrogen charging pipeline assembly A is arranged on the tank top. The tank bottom is provided with an eccentric double-layer paddle stirrer 8.

As shown in fig. 1-4, the vacuumizing-nitrogen charging pipeline assembly a comprises a nitrogen charging branch pipe 9, a vacuumizing branch pipe 10, a main pipeline 11 and a vacuumizing-nitrogen charging head 12; the main pipeline penetrates into the operation tank; the nitrogen charging branch pipe and the vacuumizing branch pipe are respectively connected with the outer end of the tank of the main pipeline, and the vacuumizing-nitrogen charging head is arranged at the inner end of the tank of the main pipeline. The vacuumizing-nitrogen filling head comprises an outer tube 121 and an inner tube 122, a gap is arranged between the outer tube and the inner tube, the top and the bottom of the inner tube are lower than the top and the bottom of the outer tube, and the bottom of the outer tube is sealed with the outer wall of the inner tube; the top of the outer tube is provided with a sealing ring 123 which can move up and down along the inner wall of the outer tube, and the outer diameter and the inner diameter of the sealing ring are respectively matched with the inner diameter of the top of the outer tube and the outer diameter of the top of the inner tube. The outer tube inner wall is located the below of sealing washer and is equipped with stopper 124, and the stopper is less than the inner tube top, and the outer tube lateral wall is located the stopper below and is equipped with air vent 125. Valves 13 are respectively arranged on the nitrogen charging branch pipe and the vacuumizing branch pipe.

As shown in fig. 5-6, the horizontal distance between the double-layer paddle stirrer and the central shaft of the operation tank or the storage tank is 1/4-1/6 of the maximum inner diameter of the tank body of the operation tank or the storage tank. The double-layer paddle stirrer and the tank body are detachable, and the upper paddle 81 and the lower paddle 82 of the double-layer paddle stirrer are respectively composed of 2 paddles; the upper layer blade forms an included angle of 10-60 degrees with the stirring shaft, the lower layer blade forms an included angle of 100-170 degrees with the stirring shaft 83, and the included angle of the upper layer blade and the lower layer blade is not less than 30 degrees under the overlooking angle. The nitrogen charging direction of the vacuumizing-nitrogen charging pipeline assembly A faces to the double-layer blade stirrer.

The transfer pump is selected from the group consisting of diaphragm pumps, peristaltic pumps, plunger pumps, rotor pumps, gear pumps, and more preferably peristaltic pumps and plunger pumps.

The filter consists of a filter shell and a filter element, wherein the filter shell is made of stainless steel, the filter element can adopt a mode of connecting a single-stage filter element or a two-stage filter element in series, the filter element is made of PES, PVDF, PTFE, PP, nylon, glass fiber and the like, and hydrophilic PVDF and PTFE are preferable.

As shown in fig. 1, an inner extension pipe 14 connected with the transmission pipeline is arranged in the storage tank, and extends along the inner side wall of the storage tank to be close to the tank bottom, wherein the distance between the bottom of the inner extension pipe and the tank bottom is not more than 50cm. The storage tank is provided with a vacuumizing-nitrogen charging pipeline component B, the tank wall of the storage tank is provided with a heat exchange jacket 7, and the tank bottom is provided with an eccentric double-layer paddle stirrer 8 (same operation tank). The vacuumizing-nitrogen charging pipeline assembly B comprises a nitrogen charging branch pipe 15, a vacuumizing branch pipe 16 and a general pipe 17; the universal pipe penetrates into the storage tank; the nitrogen-charging branch pipe and the vacuumizing branch pipe are respectively connected with one end of the universal pipe, which is positioned outside the tank, and further preferably, the distance between the bottom of the universal pipe and the bottom of the tank is not more than 1/2 of the height in the tank. The nitrogen-charging branch pipe and the vacuumizing branch pipe are respectively provided with a valve 13.

Further, preferably, the top or side walls of the operating tank and the storage tank are provided with a viewing window, and the tank is provided with an oxygen dissolving electrode 18.

Example 1

A deoxidizing device for a surfactant solution, comprising an operation tank 1, a storage tank 2, a transfer line 3, a filter 4, and a transfer pump 5 (peristaltic pump). Two ends of the transmission pipeline are respectively communicated with the bottom of the operation tank and the side wall of the storage tank; the filter and the transfer pump are arranged on the transfer pipeline. Specifically:

the tank top of the operation tank is provided with a charging port 6, the tank wall of the operation tank is provided with a heat exchange jacket 7, and the tank top is provided with a vacuumizing-nitrogen charging pipeline assembly A. The tank bottom is provided with an eccentric double-layer paddle stirrer 8. An oxygen dissolving electrode 18 is arranged in the tank.

The vacuumizing-nitrogen charging pipeline assembly A comprises a nitrogen charging branch pipe 9, a vacuumizing branch pipe 10, a main pipeline 11 and a vacuumizing-nitrogen charging head 12; the main pipeline penetrates into the operation tank; the nitrogen charging branch pipe and the vacuumizing branch pipe are respectively connected with the outer end of the tank of the main pipeline, and the vacuumizing-nitrogen charging head is arranged at the inner end of the tank of the main pipeline. The vacuumizing-nitrogen filling head comprises an outer tube 121 and an inner tube 122, a gap is arranged between the outer tube and the inner tube, the top and the bottom of the inner tube are lower than the top and the bottom of the outer tube, and the bottom of the outer tube is sealed with the outer wall of the inner tube; the top of the outer tube is provided with an annular sealing ring 123 which can vertically displace along the inner wall of the outer tube, the sealing ring is made of rubber material, and the outer diameter and the inner diameter of the sealing ring are respectively matched with the inner diameter of the top of the outer tube and the outer diameter of the top of the inner tube. An annular limiting block 124 is arranged below the sealing ring on the inner wall of the outer tube, the limiting block is lower than the top of the inner tube, and a vent 125 is arranged below the limiting block on the side wall of the outer tube. Valves 13 are respectively arranged on the nitrogen charging branch pipe and the vacuumizing branch pipe.

The horizontal distance between the double-layer paddle stirrer and the central shaft of the operation tank is 1/5 of the maximum inner diameter of the tank body of the operation tank. The double-layer paddle stirrer and the tank body are detachable, and the upper paddle 81 and the lower paddle 82 of the double-layer paddle stirrer are respectively composed of 2 paddles; the upper layer blade forms an included angle of 45 degrees with the stirring shaft, the lower layer blade forms an included angle of 135 degrees with the stirring shaft 83, and the included angle of the upper layer blade and the lower layer blade is 45 degrees under the overlooking angle. The nitrogen charging direction of the vacuumizing-nitrogen charging pipeline assembly A faces to the double-layer blade stirrer.

The filter consists of a filter shell and a filter element, wherein the filter shell is made of stainless steel, the filter element adopts a single-stage filter element, and the material is hydrophilic PVDF.

An inner extension pipe 14 connected with the transmission pipeline is arranged in the storage tank, and extends along the inner side wall of the storage tank to be close to the tank bottom, and the distance between the bottom of the inner extension pipe and the tank bottom is not more than 50cm. The storage tank is provided with a vacuumizing-nitrogen charging pipeline component B, the tank wall of the storage tank is provided with a heat exchange jacket 7, and the tank bottom is provided with an eccentric double-layer paddle stirrer 8 (same operation tank). An oxygen dissolving electrode 18 is arranged in the tank. The vacuumizing-nitrogen charging pipeline assembly B comprises a nitrogen charging branch pipe 15, a vacuumizing branch pipe 16 and a general pipe 17; the universal pipe penetrates into the storage tank; the nitrogen-charging branch pipe and the vacuumizing branch pipe are respectively connected with one end of the universal pipe, which is positioned outside the tank, and the distance between the bottom of the universal pipe and the bottom of the tank is not more than 1/2 of the height in the tank. The nitrogen-charging branch pipe and the vacuumizing branch pipe are respectively provided with a valve 13.

The application method of the deoxidizing device of the embodiment comprises the following steps: the feed port was opened, the surfactant solution was added to the run tank, and the feed port was closed. Controlling the temperature of the solution through a heat exchange jacket, and simultaneously starting a stirrer; and (3) vacuumizing the operation tank, stopping changing the operation tank into nitrogen filling, repeating the operation for a plurality of times, detecting the concentration of the dissolved oxygen, filtering the solution through a filter by a transmission pipeline after the concentration reaches a target value, and conveying the solution into the storage tank. Wherein, the storage tank is subjected to vacuumizing and nitrogen filling treatment in advance so as to ensure that the tank is in an anaerobic environment, and the surfactant solution can be discharged from a discharge hole (not shown in the figure) arranged at the bottom of the storage tank during discharging.

The foregoing description is only a preferred embodiment of the present utility model, and is not intended to limit the present utility model, and any simple modification, variation and equivalent structural transformation made according to the technical substance of the present utility model still fall within the scope of the technical solution of the present utility model.

Claims (10)

1. A deoxidizing device for a surfactant solution, characterized by: comprises an operation tank, a storage tank, a transmission pipeline and a transmission pump; two ends of the transmission pipeline are respectively communicated with the bottom of the operation tank and the side wall of the storage tank; the transmission pump is arranged on the transmission pipeline;

a charging port is arranged on the operation tank, and a vacuumizing-nitrogen charging pipeline assembly A is arranged on the tank top;

the vacuumizing-nitrogen charging pipeline assembly A comprises a nitrogen charging branch pipe, a vacuumizing branch pipe, a main pipeline and a vacuumizing-nitrogen charging head; the main pipeline penetrates into the operation tank; the nitrogen charging branch pipe and the vacuumizing branch pipe are respectively connected with the outer end of the tank of the main pipeline, and the vacuumizing-nitrogen charging head is arranged at the inner end of the tank of the main pipeline;

the vacuumizing-nitrogen filling head comprises an outer pipe and an inner pipe, a gap is arranged between the outer pipe and the inner pipe, the top and the bottom of the inner pipe are lower than the top and the bottom of the outer pipe, and the bottom of the outer pipe is sealed with the outer wall of the inner pipe; the top of the outer tube is provided with a sealing ring which can move up and down along the inner wall of the outer tube, and the outer diameter and the inner diameter of the sealing ring are respectively matched with the inner diameter of the top of the outer tube and the outer diameter of the top of the inner tube;

a limiting block is arranged on the inner wall of the outer tube below the sealing ring, the limiting block is lower than the top of the inner tube, and a vent is arranged on the side wall of the outer tube below the limiting block;

the storage tank is provided with a vacuumizing-nitrogen charging pipeline component B, the tank walls of the operation tank and the storage tank are respectively provided with a heat exchange jacket, and the tank bottom is respectively provided with an eccentric double-layer paddle stirrer.

2. The deoxidizing device of claim 1, wherein: and a filter is arranged on the transmission pipeline.

3. The deoxidizing device of claim 1, wherein: and the nitrogen charging direction of the vacuumizing-nitrogen charging pipeline assembly A faces to the double-layer blade stirrer.

4. A deoxidizing device as claimed in claim 3, wherein: the horizontal distance between the double-layer paddle stirrer and the central shaft of the operation tank or the storage tank is 1/4-1/6 of the maximum inner diameter of the tank body of the operation tank or the storage tank.

5. A deoxidizing device as claimed in claim 1 or claim 3, wherein: the upper layer blade and the lower layer blade of the double-layer blade stirrer are respectively composed of 2 blades; the upper layer blade and the stirring shaft form an included angle of 10-60 degrees, the lower layer blade and the stirring shaft form an included angle of 100-170 degrees, and the included angle of the upper layer blade and the lower layer blade under the overlooking angle is not less than 30 degrees.

6. The deoxidizing device of claim 1, wherein: the top or the side wall of the operation tank and the storage tank are provided with visual windows, and dissolved oxygen electrodes are arranged in the tank.

7. The deoxidizing device of claim 1, wherein: the transfer pump is selected from a diaphragm pump, a peristaltic pump, a plunger pump, a rotor pump, and a gear pump.

8. The deoxidizing device of claim 1, wherein: the vacuumizing-nitrogen charging pipeline component B comprises a nitrogen charging branch pipe, a vacuumizing branch pipe and a general pipe; the universal pipe penetrates into the storage tank; the nitrogen-charging branch pipe and the vacuumizing branch pipe are respectively connected with one end of the universal pipe, which is positioned outside the tank.

9. The deoxidizing device of claim 8, wherein: and valves are respectively arranged on the nitrogen charging branch pipe, the vacuumizing branch pipe, the nitrogen charging branch pipe and the vacuumizing branch pipe.

10. The deoxidizing device of claim 1, wherein: an inner extension pipe connected with the transmission pipeline is arranged in the storage tank, and extends to be close to the tank bottom along the inner side wall of the storage tank.