CN220413395U - Integrated reagent detection device - Google Patents

Abstract

The present utility model provides an integrated reagent detection device comprising: the device comprises a shell, a detection body for placing detection test paper, a drainage unit, a reaction chamber and a sampling piece, wherein the shell is provided with a containing cavity, and the detection body is connected with the drainage unit and is arranged in the containing cavity; the reaction chamber is arranged in the accommodating cavity together and is adjacent to the drainage unit, the reaction chamber is isolated from the drainage unit through the sealing unit, the reaction chamber is internally provided with reaction liquid, and the sealing unit is in a sealing or communicating state. The integrated reagent detection device is convenient to carry and not easy to pollute, the packaging cost is saved, the detection process is completed in the closed accommodating cavity, the hand touch in the detection process is avoided, the bacteria pollution is avoided, the accuracy of the detection result is improved, the rapid detection can be realized, and the detection efficiency is improved. And the device can be used for sampling and fixing by only operating the sampling piece, and is simple and convenient to operate.

Description

Integrated reagent detection device

Technical Field

The utility model relates to the field of reagent detection devices, in particular to an integrated reagent detection device.

Background

With the increasing importance of people on health, the demands for life sciences and medical research are increasing. Meanwhile, the emerging biotechnology and accurate medical technology provide new power for the development of the market of the reagent detection device.

On the market, the novel crown antigen self-test kit comprises: sampling swab, sample extract, detection kit, and medical waste special processing bag, split type packaging makes multiclass packing, leads to the enterprise to need increase the cost when producing and purchasing. In the whole detection process, it is noted that in the detection process, the extracting solution is not required to be touched by hands, so that bacterial pollution is avoided, meanwhile, the accuracy of a detection result is influenced, after a sample is obtained, detection is required to be carried out as soon as possible, and the detected waste can not be randomly separated and treated in a scattered manner so as not to cause virus transmission. The whole detection flow is required to be carried out according to the specification, the steps and the requirements in sequence.

Through searching, application number 202110310169.7 and publication number CN 112921121A disclose a nucleic acid detection kit and a rapid detection method, which utilize a drip nozzle of a collection drip bottle to extrude out controllable liquid drop number, so as to realize detection in living or outdoor scenes outside a laboratory. However, this method is also a split package during actual use, and cannot ensure that the drip nozzle of the collection drip bottle is not touched by hand, avoiding contamination by bacteria.

Disclosure of Invention

The utility model aims to provide an integrated reagent detection device, which solves the problems that a split reagent detection device is inconvenient to carry and easy to pollute, and the packaging cost is wasted, and can not avoid touching reaction liquid by hands in the detection process, and can not avoid the reaction liquid being polluted by bacteria, thereby affecting the accuracy of a detection result, and meanwhile, the integrated reagent detection device has the risk of not detecting in time, has a plurality of operation steps, and has a somewhat complex operation flow for children and old people.

The utility model provides an integrated reagent detection device, comprising: the device comprises a shell, a detection body for placing detection test paper, a drainage unit, a reaction chamber and a sampling piece, wherein an accommodating cavity is arranged on the shell; the detection body is connected with the drainage unit and is arranged in the accommodating cavity; the reaction chamber is arranged in the accommodating cavity together and adjacent to the drainage unit, the reaction chamber is isolated from the drainage unit by the sealing unit, the reaction chamber is internally provided with reaction liquid, and the sealing unit is in a sealing or communicating state; the sampling piece is movably arranged in the accommodating cavity and is in a non-contact state with the reaction liquid of the reaction chamber; under the detection state, the sampling piece with the sampling liquid stretches into the reaction chamber to react with the reaction liquid, and the sealing unit is in the communication state, and the reaction chamber is communicated with the drainage unit, and the reaction liquid is drained to the detection body and is detected through the detection test paper.

Preferably, the accommodating cavity is cylindrical, the detection body and the reaction chamber are arranged in the accommodating cavity in parallel, the drainage unit is arranged below the detection body and the reaction chamber, one end of the drainage unit is communicated with the detection body, and the other end of the drainage unit is positioned below the reaction chamber.

Preferably, the sealing unit adopts a sealing film, and the sealing unit is in a communicating state and is opened into the communicating state by arranging the sealing film.

Preferably, the sampling piece is movably arranged at the end part of the cavity opening of the accommodating cavity.

Preferably, the sampling member is fixedly installed at the end part of the cavity opening of the accommodating cavity through the first installation member, and the sampling member is separated from the accommodating cavity through the first installation member so as to realize sampling.

Preferably, the sampling member is fixed in the accommodating cavity through the second mounting member, and the sampling head of the sampling member reacts with the reaction liquid in the reaction chamber.

Preferably, the second mounting member is provided with a movable stroke adapted to the stroke of the sampling head breaking the sealing unit.

Preferably, the second mounting piece is a knob, the knob is in threaded fit with the screw thread arranged in the accommodating cavity, and the screw thread stroke of the knob is a movable stroke.

Preferably, the first mounting member is a fixing cap fixed on the accommodating cavity.

Preferably, the detection pipeline is provided with a testing device, the testing device comprises a window and a testing sheet, the window is a transparent area, the external device is provided with a marking line, and the testing sheet is arranged in the window.

Compared with the prior art, the utility model has the beneficial effects that:

firstly, the detection body, the drainage unit, the reaction chamber and the sampling piece are arranged in a containing cavity, so that the integrated reagent detection device is realized, the device is convenient to carry and not easy to pollute, and the packaging cost is saved. According to the utility model, in the non-detection state, the sampling piece is fixed in the accommodating cavity, the reaction liquid of the reaction chamber and the sampling piece are in a non-contact state and are physically isolated, the sampling piece is movably fixed in the accommodating cavity, in the detection state, the sampling piece can leave the accommodating cavity to sample, the reaction liquid of the reaction chamber and the sampling piece are contacted and then react, the sealing unit is communicated with the drainage unit in the communication state, the reaction liquid is drained to the detection body, and the detection is carried out by the detection test paper.

Then, the detection body and the reaction chamber are arranged in the accommodating cavity in parallel, the drainage unit is arranged below the detection body and the reaction chamber, one end of the drainage unit is communicated with the detection body, and the other end of the drainage unit is positioned below the reaction chamber. Therefore, the reaction liquid is detected in the closed accommodating cavity, the reaction liquid is prevented from being touched by hands in the detection process, bacterial pollution is avoided, and the accuracy of the detection result is improved.

Meanwhile, the reaction chamber is isolated from the drainage unit through the sealing unit, the sealing unit is a sealing film, the sealing or communicating state of the sealing unit can be changed, the second mounting piece is provided with a movable stroke, the movable stroke is matched with the stroke of the sealing unit when the sampling head breaks, a detection sample can be timely detected, and the detection efficiency is improved.

Further, the sampling piece can be fixedly arranged at the end part of the cavity opening of the accommodating cavity through the first mounting piece and the second mounting piece, and the whole process of sampling and detecting can be completed only by operating the sampling piece, so that the operation is simple and convenient.

Drawings

FIG. 1 is a schematic diagram of an integrated reagent detection device according to an embodiment of the present utility model;

FIG. 2 is a schematic diagram illustrating a first procedure of an integrated reagent testing device according to an embodiment of the present utility model;

FIG. 3 is a schematic diagram of a second stroke of the integrated reagent detection device according to the embodiment of the present utility model;

FIG. 4 is a schematic diagram of a third stroke of the integrated reagent detection device according to the embodiment of the present utility model;

in the figure:

10-shell

11-reaction chamber

12-specimen

13-drainage unit

14-sealing unit

20-sampling piece

30-containing cavity

21-sampling head

22-first mounting member

23-second mounting member

Detailed Description

The present utility model will be described in detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the present utility model, but are not intended to limit the utility model in any way. It should be noted that variations and modifications could be made by those skilled in the art without departing from the inventive concept. These are all within the scope of the present utility model.

Please refer to fig. 1, which is a schematic structural diagram of an integrated reagent detecting apparatus, the integrated reagent detecting apparatus includes: the device comprises a shell 10, a detection body 12 for placing detection test paper, a drainage unit 13, a reaction chamber 11 and a sampling piece 20, wherein an accommodating cavity 30 is arranged on the shell 10, and the detection body 12 is connected with the drainage unit 13 and is arranged in the accommodating cavity 30; the reaction chamber 11 is disposed in the accommodating cavity 30 and adjacent to the drainage unit 13, the reaction chamber 11 is isolated from the drainage unit 13 by the sealing unit 14, the reaction chamber 11 is provided with a reaction liquid, and the sealing unit 14 is in a sealed or communicating state.

The housing 10 may be a containing body, where the detecting body 12 and the sampling member 20 are respectively contained in the containing body of the housing, the reaction chamber 11 is disposed below the sampling member 20, and the reaction chamber 11 is communicated with the detecting body 12 through the drainage unit 13 (mainly refers to a flow channel of a subsequent reaction solution). Of course, the housing 10 may be formed as two receiving members having a bottom portion in communication with each other, one receiving the detecting body 12 and one receiving the sampling member 20 and the reaction chamber 11. The bottom of the accommodating body is communicated so that the subsequent reaction liquid has a circulation channel. The reaction chamber 11 may be directly disposed at the bottom of the accommodating body. The two receptacles may be a non-separate component. The core of the utility model is to provide an integrated reagent detection device, which realizes the reaction and detection of a collection liquid in a shell.

In this embodiment, the housing 10 adopts a cylindrical structure with a bottom, an opening at the top, and a parallel closed cavity with the bottom communicated and protruding outwards. Generally, chlorinated Polyethylene (PEC) is a common material for manufacturing shells, and also can be made of imported polypropylene (PP) materials and medical PE materials. The housing may be soft or hard.

When the reaction liquid enters the detection body 12 in the detection state, the reaction liquid meets the detection paper, and the detection result can be reflected by the detection paper. This is a common detection method, and further, the detection body 12 may be provided with a transparent window for displaying the test result, so as to facilitate checking the test result. Corresponding windows for displaying test results are arranged at corresponding positions on the shell.

The drainage unit 13 is for draining the reaction liquid. Common drainage ways are sliver drainage and tubular drainage. In this embodiment, a tubular drainage is adopted, and the accommodating cavity 30 is cylindrical.

The reaction chamber 11 is provided with a reaction liquid, and the reaction chamber 11 may be a sealed space formed by the sealing unit 14. The sealing unit 14 may be in a semi-opened state, but the sealing unit 14 is provided at the bottom. The sealing unit 14 may be a sealing membrane, and the sampling member 20 may be opened with its end portion after the mixing reaction of the sampling liquid and the reaction liquid. The reacted liquid passes through the drainage unit 13 to the specimen 12.

The sampling member 20 may be a sampling swab. The sampling rod comprises a sampling swab at one end, and a mounting piece at the other end, wherein the mounting piece is movably connected with the end part of an cavity opening of the accommodating cavity. When sampling is required, the sampling member 20 is taken out from the accommodating cavity for sampling. When the detection device is not in use, the sampling member 20 is fixed in the cavity by the mounting member, and sealing is achieved by the mounting member.

The mounting elements of the sampling member 20 may include a first mounting element and a second mounting element. The sampling piece can be fixedly arranged at the end part of the cavity opening of the accommodating cavity through the first mounting piece, and the sampling piece can be separated from the accommodating cavity through the first mounting piece so as to realize sampling. The sampling piece can be fixed in the accommodating cavity through the second mounting piece, and the sampling head of the sampling piece reacts with the reaction liquid arranged in the reaction chamber. For example, the second mounting member is provided with a movable stroke which is adapted to the stroke of the sampling head breaking the sealing unit. The second mounting piece can adopt the ammonium button, and the holding cavity corresponds the place and sets up the spiral of one section stroke (for example stroke distance is L1), and the one end of sampling rod is the ammonium button, and the initial position of ammonium button can sample the piece setting on the reaction liquid of reaction chamber, with the non-contact of reaction liquid. After the sampled sample is obtained, the button moves from the initial position to the reaction chamber through the spiral, and simultaneously drives the sampling piece to react after contacting with the reaction liquid, and the reaction is fully carried out. The button is rotated towards the direction of the reaction chamber until the sampling rod breaks the sealing film, so that the reaction liquid is drained through the drainage unit 13.

That is, the second mounting piece is a knob, the knob is in threaded fit with the screw thread arranged in the accommodating cavity, and the screw thread stroke of the knob is a movable stroke. The first mounting member may be a fixing cap fixed to the accommodating chamber.

Referring to fig. 2, which is a first schematic travel diagram of the integrated reagent detecting apparatus, the sampling member 20 is movably disposed in the accommodating cavity 30 and is in a non-contact state with the reaction solution in the reaction chamber 11. Please refer to fig. 3, which is a second schematic diagram of the integrated reagent detecting apparatus, in the detecting state, the sampling member 20 is sampled, and the sampling member 20 is extended into the reaction chamber 11 to react with the reaction solution. Referring to fig. 4, which is a third schematic diagram of the integrated reagent testing device, the sealing unit 14 is in communication with the reaction chamber 11 and the drainage unit 13, and the reaction liquid is drained to the testing body 12 and tested by the test paper.

Referring to fig. 4, the detecting body 12 and the reaction chamber 11 are disposed in parallel in the accommodating cavity 30, the drainage unit 13 is disposed below the detecting body 12 and the reaction chamber 11, one end is connected to the detecting body 12, and the other end is located below the reaction chamber 11. In the detection state, the drainage means 13 drains the reaction solution from below the reaction chamber 11 into the detection body 12.

Referring to fig. 3-4, the sealing unit 14 is broken, and the reaction liquid reacts with the sample on the sampling member 20. The sealing unit 14 may be broken by crushing the sealing unit 14, or by increasing the internal pressure of the casing to cause the sealing unit 14 to be broken, or by puncturing the sealing unit 14 with the sampling member 20, or by opening the sealing unit 14 in the form of a tab. The sealing unit 14 may be made of a material that is broken by a stamp, or a material that is easily crushed and torn, such as a PE or PP film commonly used in the market.

The reaction liquid in the reaction chamber 11 is detected in the accommodating cavity 30, so that the reaction liquid is prevented from being touched by hands in the detection process, bacterial pollution is avoided, and the accuracy of the detection result is improved. Further, the sealing unit 14 is in a communicating state, the reaction chamber 11 is communicated with the drainage unit 13, and the reaction liquid is drained to the detection body 12 and is further detected by the detection test paper.

The reaction chamber 11 is provided with a reaction liquid, and the reaction liquid is combined with a detection sample and detected by detection test paper. The reaction solution used in this example was designed to provide the maintenance of the environmental conditions required for detection to ensure that the bioactive material remained intact. For example: the antigen extracting solution is widely used for nucleic acid detection. Before the reaction solution is prepared, the type and amount of the reaction solution to be used need to be accurately checked. In market practice, nucleic acid nasal swab detection is mainly carried out by taking secretions on the inner side of a nasal cavity and the surface of a nasal mucosa through a sampling swab through the nasal cavity, and placing the nasal swab stained with the secretions into an antigen extracting solution to enable the nasal swab to be fully mixed with the antigen extracting solution. The total amount of the antigen extract is 0.3 ml, and the antigen extract contains Tris-HCL, surfactant, purified water and the like, and the antigen detection sample extract contains Tris-HCL, tween-20, purified water and the like, or PBS, brij58, ultrapure water and the like.

In this embodiment, the detecting body 12, the drainage unit 13, the reaction chamber 11 and the sampling member 20 are disposed in a housing cavity 30, so as to realize an integrated reagent detecting device, which is convenient to carry and not easy to pollute, and saves packaging cost.

In this embodiment, the sampling member 20 is movably disposed at the end of the cavity opening of the accommodating cavity 30. The sampling member 20 can be movably connected with the end of the cavity opening of the accommodating cavity 30 in a clamping, sleeving, plugging and screwing manner. The sampling member 20 can seal and fix the cavity opening, and can be movably opened to realize sampling when the detection is ready.

The first mounting member 22 and the second mounting member 23 may be integrally formed or may be separately formed. In this embodiment, the second mounting member 23 is connected to the housing 10 in a screwed manner, the second mounting member 23 is screwed into the housing, and the sampling head 21 pierces the sealing unit 14 to react with the reaction liquid disposed in the reaction chamber 11. Further, the portion of the reaction chamber 11 located in the housing 10 may be provided to be transparent, so that it is clearly observed that the sealing unit is in a communicating state and sufficiently combined with the reaction liquid provided in the reaction chamber 11. Further, a marking line may be provided on the second mounting member 23, which indicates that the sampling head 21 reacts with the reaction liquid in combination when the marking line is flush with the end of the cavity mouth of the accommodating cavity 30. May be stopped slightly. Referring to fig. 4, the sealing unit 14 is in a communicating state, the reaction chamber 11 is communicated with the drainage unit 13, and the reaction liquid is drained to the detecting body 12, so as to be detected by the detecting test paper. The whole process of sampling and detecting can be completed by only operating the sampling piece 20, and the operation is simple and convenient.

The foregoing describes specific embodiments of the present utility model. It is to be understood that the utility model is not limited to the particular embodiments described above, and that various changes or modifications may be made by those skilled in the art within the scope of the appended claims without affecting the spirit of the utility model. The embodiments of the present application and features in the embodiments may be combined with each other arbitrarily without conflict.

Claims (10)

1. An integrated reagent testing device, comprising: casing, be used for placing detection test paper's detection body, drainage unit, reaction chamber and sampling piece, wherein:

the shell is provided with an accommodating cavity;

the detection body is connected with the drainage unit and is arranged in the accommodating cavity;

the reaction chamber is arranged in the accommodating cavity, is adjacent to the drainage unit, is isolated from the drainage unit by a sealing unit, is provided with reaction liquid, and is in a sealed or communicated state;

the sampling piece is movably arranged in the accommodating cavity and is in a non-contact state with the reaction liquid of the reaction chamber;

under the detection state, the sampling piece with sampling liquid stretches into the reaction chamber to react with the reaction liquid, and the sealing unit is in the communication state the reaction chamber is communicated with the drainage unit, and the reaction liquid is drained to the detection body and is detected through detection test paper.

2. The integrated reagent testing device according to claim 1, wherein the accommodating cavity is cylindrical, the testing body and the reaction chamber are arranged in the accommodating cavity in parallel, the drainage unit is arranged below the testing body and the reaction chamber, one end of the drainage unit is communicated with the testing body, and the other end of the drainage unit is arranged below the reaction chamber.

3. The integrated reagent testing device according to claim 1, wherein the sealing unit is a sealing film, and the sealing unit is placed in a communicating state by being opened by providing the sealing film.

4. The integrated reagent testing device of claim 1, wherein the sampling member is movably disposed at an end of the cavity opening of the receiving cavity.

5. The integrated reagent testing device according to claim 4, wherein the sampling member is fixedly mounted at the mouth end of the accommodating chamber by a first mounting member, and the sampling member is separable from the accommodating chamber by the first mounting member to perform sampling.

6. The integrated reagent testing device according to claim 4 or 5, wherein the sampling member is fixed in the accommodating chamber by a second mounting member, and the sampling head of the sampling member reacts with the reaction liquid provided in the reaction chamber.

7. The integrated reagent testing device according to claim 6, wherein the second mounting member is provided with a movable stroke adapted to the stroke of the sampling head to break the sealing unit.

8. The integrated reagent testing device according to claim 7, wherein the second mounting member is a knob which is screwed into the housing cavity, and the screw stroke of the knob is the movable stroke.

9. The integrated reagent testing device of claim 5, wherein the first mounting member is a retaining cap secured to the receiving chamber.

10. The integrated reagent testing device according to claim 1, wherein the testing body is provided with a testing device, the testing device comprises a window and a testing paper, the window is a transparent area, an identification line is arranged outside the window, and the testing paper is arranged in the window.