CN220265697U - Electrode detection system of disposable biological culture bag - Google Patents
Electrode detection system of disposable biological culture bag Download PDFInfo
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- CN220265697U CN220265697U CN202321598695.9U CN202321598695U CN220265697U CN 220265697 U CN220265697 U CN 220265697U CN 202321598695 U CN202321598695 U CN 202321598695U CN 220265697 U CN220265697 U CN 220265697U
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- 238000001514 detection method Methods 0.000 title claims abstract description 76
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 11
- 238000000034 method Methods 0.000 claims description 4
- 239000001963 growth medium Substances 0.000 abstract description 16
- 238000004519 manufacturing process Methods 0.000 abstract description 12
- 238000009434 installation Methods 0.000 abstract description 7
- 238000012545 processing Methods 0.000 abstract description 7
- 238000006243 chemical reaction Methods 0.000 abstract description 6
- 241000894006 Bacteria Species 0.000 abstract description 4
- 238000005070 sampling Methods 0.000 abstract description 4
- 208000015181 infectious disease Diseases 0.000 abstract description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
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Abstract
The utility model discloses an electrode detection system of a disposable biological culture bag, which belongs to the field of biological culture and comprises a detection device; the detection device comprises a support body, a channel which is arranged on the support body and is communicated with the bag body of the disposable biological culture bag, and a detection electrode which is fixed on the support body and extends into the channel; the detection system further includes a peristaltic pump disposed between the channel and the bag for pressurizing. According to the electrode detection system, the detection electrode is arranged externally, a culture medium is detected in a circulating sampling mode, the installation space of the detection electrode is not needed to be considered, and the production and processing of the disposable biological reaction bag can be effectively facilitated; meanwhile, the electrode detection system can be reused, so that the cost of biological culture is effectively reduced; and the risk of bacteria infection can be effectively reduced, and the safety of biological culture is improved.
Description
Technical Field
The utility model relates to the technical field of biological culture, in particular to an electrode detection system of a disposable biological culture bag.
Background
In the production and manufacturing of biological products, the use of bioreactors is not separated, and bioreactors are known to be classified into reusable and disposable systems. The bioreactor which is repeatedly used needs to be subjected to comprehensive sterilization and disinfection before being used, and the reactor system needs to be cleaned after batch culture is finished, especially in the aspect of drug production and development, strict cleaning and verification are needed to be carried out on equipment cleaning, so that time and labor are wasted.
There are also many disposable bioreactors on the market at present, such as: chinese patent publication No. CN115369009a discloses a disposable bioreactor complete set. The disposable bioreactor complete equipment comprises a mass transfer system module, a driving system module and a bag body module, wherein the bag body module is at least provided with a DO electrode port and a pH electrode port. The structure is compact and the operation is convenient. However, the DO electrode port and the pH electrode port are arranged on the bag body module, and when the bag body module is processed and produced, the installation position of the detection electrode needs to be reserved, so that the production and the processing of the disposable biological reaction bag are inconvenient; secondly, the detection electrode is welded on the bag body module to form an integrated disposable device, and the detection electrode is not reusable and has high cost; and the bacteria are easy to be infected in the operation process, so that the safety of biological culture is affected.
Accordingly, the present application provides an electrode detection system for a disposable biological growth bag to address the above-described problems.
Disclosure of Invention
(one) solving the technical problems
The utility model provides an electrode detection system of a disposable biological culture bag, which aims to solve the problems that an existing disposable biological culture bag provided in the background art is provided with a detection electrode interface reserved on a bag body, and the installation space of a detection electrode needs to be considered during production, so that the production and the processing of a reaction bag are inconvenient; the detection electrode can not be reused, the cost is high, bacteria are easy to be infected in the installation and operation process, the biological culture safety is affected, and the like.
(II) technical scheme
In order to achieve the above purpose, the present utility model provides the following technical solutions: an electrode detection system for a disposable biological growth bag, the detection system comprising a detection device.
In order to externally arrange the detection electrode, detecting the culture medium in the bag body in a circulating sampling mode; the detection device comprises a support body, a channel which is arranged on the support body and is communicated with the bag body of the disposable biological culture bag, and a detection electrode which is fixed on the support body and extends into the channel; the detection system further includes a peristaltic pump disposed between the channel and the bag for pressurizing.
Preferably, the detection electrode at least comprises a pH value detection electrode and a DO value detection electrode.
Preferably, in order to communicate the bag body with the channel, the culture medium in the bag body can flow back into the bag body after passing through the channel, so as to realize circulation of the culture medium; the support body is provided with two ports communicated with the channels, and the two ports are communicated with the bag body through a pipeline; wherein the peristaltic pump is disposed on one of the tubes.
Preferably, in order to facilitate the communication between the channel and the bag body, a first plug is arranged at a position on the bag body corresponding to the pipeline, and a second plug matched and butted with the first plug is arranged at one end of the pipeline away from the channel.
(III) beneficial effects
According to the electrode detection system, the detection electrode is arranged externally, a culture medium is detected in a circulating sampling mode, the installation space of the detection electrode is not needed to be considered, and the production and processing of the disposable biological reaction bag can be effectively facilitated;
the electrode detection system can be reused, so that the cost of biological culture is effectively reduced; and the risk of bacteria infection can be effectively reduced, and the safety of biological culture is improved.
Drawings
FIG. 1 is a schematic diagram of an electrode detection system of a disposable biological growth bag;
FIG. 2 is a schematic diagram showing the structure of a detecting device in an electrode detecting system of a disposable biological growth bag.
In the figure:
1. a bag body; 2. a detection device; 21. a support body; 211. a port; 22. a channel; 23. a detection electrode; 3. peristaltic pump.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Example 1
The present embodiment provides an electrode detection system for a disposable biological growth bag, as shown in fig. 1 and 2, which includes a detection device 2.
The detection device 2 comprises a support 21, a channel 22 arranged on the support 21 and communicated with the bag body 1 of the disposable biological culture bag, and a detection electrode 23 fixed on the support 21 and extending into the channel 22; the detection system further comprises a peristaltic pump 3 arranged between the channel 22 and the bag 1 for pressurizing. Wherein the detection electrode 23 comprises at least a pH value detection electrode and a DO value detection electrode.
When the disposable biological reaction bag is used, the culture medium in the bag body 1 of the disposable biological reaction bag is introduced into the channel 22 through the peristaltic pump 3, so that the detection electrode 23 detects the culture medium flowing into the channel 22, the external arrangement of the detection electrode 23 is realized, the installation position of the detection electrode is not required to be reserved in production, and the production and the processing of the bag body 1 are facilitated; under the continuous pressure increase of the peristaltic pump 3, the culture medium can circulate through the channel 22, and the detection of the culture medium in the bag body 1 by the detection electrode 23 is completed.
The electrode detection system adopts the external detection electrode to detect the culture medium, so that the installation position of the detection electrode is not required to be reserved in the bag body processing production, and the production and the processing of the disposable biological culture bag are convenient.
Secondly, if the detection electrode is welded on the bag body to form a disposable product, the detection electrode is difficult to reuse, and the cost of biological culture is affected; the detection system is externally provided with the detection electrode, and the culture medium is detected in a circulating sampling mode, so that the detection system can be reused, and the cost of biological culture can be effectively reduced.
Further, the support body 21 is provided with two ports 211 communicated with the channel 22, and the two ports 211 are communicated with the bag body 1 through a pipeline 4; peristaltic pump 3 is provided on one of the tubes 4. In the detection process, the peristaltic pump 3 introduces the culture medium in the bag body 1 into the channel 22 through the pipeline 4 and one of the ports 211, and then the culture medium enters the substitution 1 through the other port 211 and the pipeline 4 to realize the circulation of the culture medium, and when the culture medium flows through the channel 22, the detection electrode 23 detects the culture medium.
Example 2
The existing disposable biological culture bag is inconvenient to actually operate and use because the detection electrode interface is arranged on the bag body, and the DO detection electrode and the pH detection electrode are required to be inserted into the bag body module through the DO electrode port and the pH electrode port respectively and then welded and sealed on the bag body module.
In order to solve the problem, this embodiment provides an electrode detection system of a disposable biological culture bag, unlike embodiment 1, a first plug 11 is disposed on the bag body 1 at a position corresponding to a pipe, and a second plug 41 that is in mating butt joint with the first plug 11 is disposed at an end of the pipe away from the channel 22.
When the detection system is used, the first plug 11 and the second plug 41 are matched, and the first plug 11 and the second plug 41 are welded in a sterile mode through welding equipment such as a pipe welding machine, so that the channel 22 is communicated with the bag body 1, the detection system and the bag body 1 can be conveniently disassembled and assembled, and the detection system is more convenient to connect and operate.
The foregoing is only a preferred embodiment of the present utility model, but the scope of the present utility model is not limited thereto, and any person skilled in the art, who is within the scope of the present utility model, should make equivalent substitutions or modifications according to the technical scheme of the present utility model and the inventive concept thereof, and should be covered by the scope of the present utility model.
Claims (5)
1. An electrode detection system for a disposable biological growth bag, the detection system comprising a detection device (2);
the method is characterized in that: the detection device (2) comprises a support body (21), a channel (22) which is arranged on the support body (21) and is communicated with the bag body (1) of the disposable biological culture bag, and a detection electrode (23) which is fixed on the support body (21) and extends into the channel (22);
the detection system further comprises a peristaltic pump (3) arranged between the channel (22) and the bag body (1) for pressurizing.
2. The electrode testing system of a disposable biological growth bag of claim 1, wherein: the detection electrode (23) at least comprises a pH value detection electrode and a DO value detection electrode.
3. The electrode testing system of a disposable biological growth bag of claim 1, wherein: the support body (21) is provided with two ports (211) communicated with the channels (22), and the two ports (211) are communicated with the bag body (1) through a pipeline (4).
4. The electrode testing system of a disposable biological growth bag of claim 3, wherein: the peristaltic pump (3) is arranged on one of the tubes (4).
5. The electrode testing system of a disposable biological growth bag of claim 3, wherein: the bag body (1) is provided with a first plug (11) at a position corresponding to the pipeline, and one end of the pipeline, which is far away from the channel (22), is provided with a second plug (41) matched and butted with the first plug (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321598695.9U CN220265697U (en) | 2023-06-21 | 2023-06-21 | Electrode detection system of disposable biological culture bag |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321598695.9U CN220265697U (en) | 2023-06-21 | 2023-06-21 | Electrode detection system of disposable biological culture bag |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220265697U true CN220265697U (en) | 2023-12-29 |
Family
ID=89312102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321598695.9U Active CN220265697U (en) | 2023-06-21 | 2023-06-21 | Electrode detection system of disposable biological culture bag |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220265697U (en) |
-
2023
- 2023-06-21 CN CN202321598695.9U patent/CN220265697U/en active Active
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