CN220231746U - Detection device for immunology experiments - Google Patents
Detection device for immunology experiments Download PDFInfo
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- CN220231746U CN220231746U CN202322173182.XU CN202322173182U CN220231746U CN 220231746 U CN220231746 U CN 220231746U CN 202322173182 U CN202322173182 U CN 202322173182U CN 220231746 U CN220231746 U CN 220231746U
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- 238000001514 detection method Methods 0.000 title claims abstract description 78
- 238000002474 experimental method Methods 0.000 title claims abstract description 26
- 230000007246 mechanism Effects 0.000 claims abstract description 32
- 238000006243 chemical reaction Methods 0.000 claims abstract description 30
- 238000004140 cleaning Methods 0.000 claims abstract description 23
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 18
- 238000005070 sampling Methods 0.000 claims description 24
- 230000001900 immune effect Effects 0.000 claims description 15
- 239000011521 glass Substances 0.000 claims description 12
- 230000006978 adaptation Effects 0.000 claims description 6
- 238000012360 testing method Methods 0.000 abstract description 6
- 238000012864 cross contamination Methods 0.000 abstract description 2
- 238000007689 inspection Methods 0.000 abstract description 2
- 238000005406 washing Methods 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 23
- 239000000126 substance Substances 0.000 description 3
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 230000031018 biological processes and functions Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000002875 fluorescence polarization Methods 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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Abstract
The utility model relates to an immunology experiment technical field specifically is a detection device for immunology experiment, including the detection case, one side of detection case is provided with the fixed station, one side of fixed station is provided with the motor, the opposite side of motor is provided with the axis of rotation, one side of axis of rotation is provided with the lead screw, be provided with the sliding block on the lead screw, the lower surface of sliding block is provided with electric putter, electric putter's lower surface is provided with detection mechanism, be provided with reaction mechanism on the inner wall of detection case, and be provided with the fixed block on the inner wall of detection case, be provided with reagent sleeve on the fixture, need not the manual work and can draw the sample automatically and carry out the inspection test, and be provided with cleaning assembly on the inner wall of detection case, through being provided with the vibration machine at the lower surface of cleaning machine, further strengthened the cleaning work to the sample needle, thereby can realize the washing to the sample needle, and then prevent the cross contamination of next experiment, ensure the accuracy of testing result each time.
Description
Technical Field
The application relates to the technical field of immunological experiments, in particular to a detection device for immunological experiments.
Background
As is well known, immunology is a bio-medical science that studies the immune response of organisms to antigenic substances and methods thereof. Immune response is the response of the body to an antigen stimulus, and is also a biological process of identifying and excluding an antigen substance, by using an experimental detection device to obtain the composition and content of the substance being detected.
The existing detection device for immunological experiments needs to be cleaned timely after detection experiments are completed, otherwise, the experimental result of the next detection is affected, but the probe and the sampling needle after detection are cleaned, so that the detection device for immunological experiments is needed.
Disclosure of Invention
(one) solving the technical problems
Aiming at the defects of the prior art, the application provides a detection device for an immunological experiment, so as to solve the problems in the background art.
(II) technical scheme
In order to achieve the above purpose, the present application provides the following technical solutions: the utility model provides a detection device for immunology experiments, includes the detection case, one side of detection case is provided with the fixed station, one side of fixed station is provided with the motor, the opposite side of motor is provided with the axis of rotation, the rotation hole with axis of rotation looks adaptation has been seted up to one side of detection case, one side of axis of rotation is provided with the lead screw, be provided with the sliding block on the lead screw, the lower surface of sliding block is provided with electric putter, electric putter's lower surface is provided with detection mechanism, be provided with reaction mechanism on the inner wall of detection case, just be provided with the fixed block on the inner wall of detection case, the upper surface of fixed block is provided with a plurality of fixture, be provided with the grip block on the fixture, just be provided with reagent sleeve on the fixture for place the experiment and await measuring the sample, be provided with cleaning assembly on the inner wall of detection case.
Preferably, the detection mechanism comprises a lifting plate, the lifting plate is arranged on the lower surface of the electric push rod, a plurality of sampling needles are arranged on one side of the lifting plate, two rotating blocks are arranged on one side of each sampling needle, a plurality of inserting grooves matched with the sampling needles are formed in the lifting plate, a plurality of rotating grooves matched with the rotating blocks are formed in the lifting plate, and the sampling needles are convenient to replace and install by experimenters.
Further, reaction mechanism includes the locating plate, the locating plate sets up on the inner wall of detection case, the upper surface of locating plate is provided with the reaction plate, a plurality of reaction holes have been seted up on the reaction plate, the lower surface of reaction plate is provided with two sliding brackets, two sliding grooves with the sliding bracket looks adaptation have been seted up on the locating plate, make things convenient for the experimenter to change the reaction plate.
Still further, fixture includes the bottom plate, the bottom plate sets up on the fixed block, and be provided with the holding ring on the bottom plate, be provided with the backup pad on the holding ring, be provided with the movable block between bottom plate and the backup pad, the spout with the movable block looks adaptation has all been seted up to the lower surface of the upper surface of bottom plate and backup pad to be provided with the fixation clamp on the movable block, be provided with electric telescopic handle on the bottom plate, can fix reagent bottle or sample tube, prevent rocking.
Further scheme, the cleaning component includes the mount, the mount sets up on the inner wall of detection case, be provided with the vibrating machine on the mount, be provided with the cleaning machine on the output of vibrating machine, the surface of cleaning machine is provided with the positioning seat, can wash the sample needle.
On the basis of the scheme, the upper surface of the detection box is provided with a placement plate, a glass plate is arranged on the placement plate, lifting grooves matched with the glass plate are formed in the placement plate, fixing pins are arranged on two sides of the placement plate, and the glass plate is isolated from the detection box when the device operates.
On the basis of the scheme, the automatic detection device is characterized in that a follow-up column is arranged on one side of the screw rod, a movable support is arranged on one side of the sliding block, a fixing strip is arranged on one side of the movable support, a movable groove matched with the movable support is formed in the fixing strip, the fixing strip is connected with the inner wall of the detection box, and the position of the sliding block can be fixed.
(III) beneficial effects
Compared with the prior art, the application provides a detection device for immunological experiments, which comprises the following components
The beneficial effects are that:
this detection device for immunology experiments, because the motor operation, the output of motor drives the axis of rotation and rotates, the axis of rotation drives the lead screw and rotates, one side of lead screw is provided with the follow-up post, the lead screw drives slider horizontal migration, the slider drives detection mechanism horizontal migration, set up reaction mechanism on the detection case inner wall, the device need not the manual work and can draw the sample automatically and carry out the inspection test, and be provided with cleaning assembly on the inner wall of detection case, thereby can realize the washing to the sample needle, and then prevent the cross contamination of next experiment, through being provided with the trembler at the lower surface of cleaning machine, further strengthened the cleaning work to the sample needle, ensure the accuracy of testing result at every turn.
Drawings
FIG. 1 is a schematic structural diagram of the present application;
FIG. 2 is an exploded view of a portion of the structure of the present application;
FIG. 3 is an exploded view of a portion of the structure of the present application;
FIG. 4 is an exploded view of a portion of the structure of the present application;
FIG. 5 is an exploded view of a portion of the structure of the present application;
fig. 6 is an exploded view of a portion of the structure of the present application.
In the figure: 1. a detection box; 2. a fixed table; 3. a motor; 4. a rotating shaft; 5. a screw rod; 6. a sliding block; 7. an electric push rod; 8. a detection mechanism; 801. a lifting plate; 802. a sampling needle; 803. a rotating block; 9. a reaction mechanism; 901. a positioning plate; 902. a reaction plate; 903. a sliding support; 10. a fixed block; 11. a clamping mechanism; 1101. a bottom plate; 1102. a support ring; 1103. a support plate; 1104. a moving block; 1105. a fixing clamp; 1106. an electric telescopic rod; 12. a clamping plate; 13. a reagent cannula; 14. cleaning the assembly; 1401. a fixing frame; 1402. a vibration machine; 1403. a cleaning machine; 1404. a positioning seat; 15. placing a plate; 16. a glass plate; 17. a fixing pin; 18. a follower column; 19. a movable support; 20. and fixing strips.
Detailed Description
The following description of the embodiments of the present application will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all, of the embodiments of the present application. All other embodiments, which can be made by one of ordinary skill in the art without undue burden from the present disclosure, are within the scope of the present disclosure.
Referring to fig. 1 to 6, a detection device for an immunological experiment includes a detection box 1, a fixed table 2 is installed at one side of the detection box 1, a motor 3 is installed at one side of the fixed table 2, the position of the motor 3 can be fixed, a rotating shaft 4 is installed at the other side of the motor 3, the rotating shaft 4 rotates, a rotating hole matched with the rotating shaft 4 is formed at one side of the detection box 1, the rotating shaft 4 rotates in the rotating hole, a screw rod 5 is installed at one side of the rotating shaft 4, the screw rod 5 rotates, a sliding block 6 is installed on the screw rod 5 in a rotating manner, the sliding block 6 can horizontally move, an electric push rod 7 is installed on the lower surface of the sliding block 6, a detection mechanism 8 is installed on the lower surface of the electric push rod 7, the detection mechanism 8 can be pushed to lift the detection mechanism 8, a reaction mechanism 9 is installed on the inner wall of the detection box 1, an extracted reagent is put into the reaction mechanism 9 for reaction test, a fixed block 10 is installed on the inner wall of the detection box 1, a plurality of clamping mechanisms 11 are installed on the upper surface of the fixed block 10, the position of the clamping mechanisms 11 can be fixed, 1105 can be installed on the clamping mechanism 11, a clamping mechanism 12 is installed on the clamping mechanism 11, a sliding mechanism 11 is installed on the inner wall 11, a sample tube is installed on the clamping mechanism 11 or a sample tube is prevented from being cleaned, and the sample tube is prevented from being polluted by sliding, and the sample can be cleaned.
Referring to fig. 1, fig. 2 and fig. 5, in this embodiment, the detection mechanism 8 includes a lifting plate 801, the lifting plate 801 is mounted on the lower surface of the electric push rod 7, the lifting plate 801 can be pushed to lift, a plurality of sampling needles 802 are rotatably mounted on one side of the lifting plate 801, the sampling needles 802 enter into a reagent bottle placed on the reagent sleeve 13 or a position 1cm below the liquid level in a sample tube to be detected, respectively absorb reagents and the sample to be detected, two rotating blocks 803 are mounted on one side of each sampling needle 802, a plurality of insertion grooves matched with the sampling needles 802 are formed on the lifting plate 801, the sampling needles 802 are inserted into the insertion grooves, a plurality of rotating grooves matched with the rotating blocks 803 are formed on the lifting plate 801, the sampling needles 802 can be disassembled by screwing, the sampling needles 802 are convenient to replace and mount the sampling needles 802, an optical detection element is arranged above the sampling needles 802, the optical detection element is used for detecting the result after the immunological reaction is completed, the absorbance, the fluorescence intensity, the time-resolved fluorescence, the fluorescence polarization, the chemiluminescence and the like of the sample are detected, the cleaning assembly 14 includes a fixing frame 1401, a vibration motor 1401 is mounted on the inner wall of the vibration box 1401, a cleaning machine is mounted on the fixing frame 1402, the cleaning machine is fixed on the outer surface of the cleaning machine is arranged, and the cleaning machine is fixed on the fixing machine is arranged, and the cleaning machine is arranged on the outer surface of the cleaning machine is arranged.
Then, referring to fig. 1 and 3, in this embodiment, the reaction mechanism 9 includes a positioning plate 901, the positioning plate 901 is mounted on the inner wall of the detection box 1, the position of the positioning plate 901 can be fixed, the upper surface of the positioning plate 901 is slidably mounted with a reaction plate 902, a plurality of reaction holes are formed on the reaction plate 902, the reagent sucked by the sampling needle 802 or the sample to be detected can be dripped into the reaction holes for reaction test of the sample and the reagent, two sliding brackets 903 are mounted on the lower surface of the reaction plate 902, two sliding grooves matched with the sliding brackets 903 are formed on the positioning plate 901, so that the sliding brackets 903 slide on the sliding grooves, the experimenter can conveniently replace the reaction plate 902, and on the positioning plate (901), commercially available conventional disposable experimental consumables can also be placed: 24-well plates, 48-well plates, 96-well plates.
Next, referring to fig. 1 and 4, in this embodiment, the clamping mechanism 11 includes a bottom plate 1101, the bottom plate 1101 is mounted on the fixed block 10, the position of the bottom plate 1101 can be fixed, a supporting ring 1102 is mounted on the bottom plate 1101, a supporting plate 1103 is mounted on the supporting ring 1102, a moving block 1104 is slidably mounted between the bottom plate 1101 and the supporting plate 1103, so that the moving block 1104 moves on a sliding groove, sliding grooves matched with the moving block 1104 are formed on the upper surface of the bottom plate 1101 and the lower surface of the supporting plate 1103, a fixing clip 1105 is mounted on the moving block 1104, a reagent bottle or a sample tube can be fixed, shaking is prevented, and an electric telescopic rod 1106 is mounted on the bottom plate 1101.
Finally, referring to fig. 1 and 6, in this embodiment, a follower post 18 is installed on one side of the screw rod 5, so as to prevent the screw rod 5 from falling off, a moving support 19 is installed on one side of the sliding block 6, a fixing bar 20 is slidably installed on one side of the moving support 19, a moving groove matched with the moving support 19 is formed in the fixing bar 20, so that the moving support 19 slides on the moving groove, the fixing bar 20 is connected with the inner wall of the detection box 1, the position of the sliding block 6 can be fixed, a placing plate 15 is installed on the upper surface of the detection box 1, a glass plate 16 is slidably installed on the placing plate 15, a lifting groove matched with the glass plate 16 is formed in the placing plate 15, the glass plate 16 can move on the lifting groove, fixing pins 17 are installed on two sides of the placing plate 15, and the position of the glass plate 16 can be fixed, so that the glass plate 16 isolates the detection box 1 when the device is operated.
Working principle:
when the detection device for the immunological experiment is used, firstly, the detection device for the immunological experiment is placed at a position required to be used, a reagent required for detection and a sample to be detected are placed in a reagent sleeve 13, an electric telescopic rod 1106 operates a fixing clamp 1105 to fix the reagent sleeve 13, a fixing pin 17 is pulled out, a glass plate 16 falls down to isolate a detection box 1 from the outside, then a motor 3 is opened, the motor 3 drives a screw rod 5 to rotate, the screw rod 5 drives a follower column 18 to rotate, the screw rod 5 rotates to drive a sliding block 6 to horizontally move above a clamping mechanism 11 on the screw rod 5, an electric push rod 7 is opened, the electric push rod 7 pushes a lifting plate 801 to downwardly move, the lifting plate 801 drives a sampling needle 802 to move, the sampling needle 802 extracts the reagent or the sample to be detected in the reagent sleeve 13, the electric push rod 7 drives the sampling needle 802 to upwardly move above the reaction plate 902, the detection reagent or the sample to be detected is extruded into a reaction hole, then the electric push rod 7 is raised, the electric push rod 7 moves the motor 3 to drive the follower 802 to rotate, the lifting plate 18 moves the sampling needle 802 to the upper side, the sampling needle 802 is pushed by the electric push rod 7 to the lifting plate 802 to the sample to be detected, and the sample to be detected is further cleaned, and the sample is further polluted by the cleaning assembly is prevented from the needle 1403.
Although embodiments of the present application have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the application, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. The utility model provides a detection device for immunology experiments, includes detection case (1), its characterized in that: one side of detection case (1) is provided with fixed station (2), one side of fixed station (2) is provided with motor (3), the opposite side of motor (3) is provided with axis of rotation (4), the rotation hole with axis of rotation (4) looks adaptation has been seted up to one side of detection case (1), one side of axis of rotation (4) is provided with lead screw (5), be provided with sliding block (6) on lead screw (5), the lower surface of sliding block (6) is provided with electric putter (7), the lower surface of electric putter (7) is provided with detection mechanism (8), be provided with reaction mechanism (9) on the inner wall of detection case (1), just be provided with fixed block (10) on the inner wall of detection case (1), the upper surface of fixed block (10) is provided with a plurality of fixture (11), be provided with grip block (12) on fixture (11), just be provided with reagent sleeve (13) on fixture (11), be provided with on the inner wall of detection case (1) and wash subassembly (14).
2. The detection device for immunological experiments according to claim 1, wherein: the detection mechanism (8) comprises a lifting plate (801), the lifting plate (801) is arranged on the lower surface of the electric push rod (7), a plurality of sampling needles (802) are arranged on one side of the lifting plate (801), two rotating blocks (803) are arranged on one side of each sampling needle (802), a plurality of inserting grooves matched with the sampling needles (802) are formed in the lifting plate (801), and a plurality of rotating grooves matched with the rotating blocks (803) are formed in the lifting plate (801).
3. The detection device for immunological experiments according to claim 1, wherein: the reaction mechanism (9) comprises a positioning plate (901), the positioning plate (901) is arranged on the inner wall of the detection box (1), a reaction plate (902) is arranged on the upper surface of the positioning plate (901), a plurality of reaction holes are formed in the reaction plate (902), two sliding supports (903) are arranged on the lower surface of the reaction plate (902), and two sliding grooves matched with the sliding supports (903) are formed in the positioning plate (901).
4. The detection device for immunological experiments according to claim 1, wherein: the clamping mechanism (11) comprises a bottom plate (1101), the bottom plate (1101) is arranged on a fixed block (10), a supporting ring (1102) is arranged on the bottom plate (1101), a supporting plate (1103) is arranged on the supporting ring (1102), a moving block (1104) is arranged between the bottom plate (1101) and the supporting plate (1103), sliding grooves matched with the moving block (1104) are formed in the upper surface of the bottom plate (1101) and the lower surface of the supporting plate (1103), a fixed clamp (1105) is arranged on the moving block (1104), and an electric telescopic rod (1106) is arranged on the bottom plate (1101).
5. The detection device for immunological experiments according to claim 1, wherein: the cleaning assembly (14) comprises a fixing frame (1401), the fixing frame (1401) is arranged on the inner wall of the detection box (1), a vibrating machine (1402) is arranged on the fixing frame (1401), a cleaning machine (1403) is arranged at the output end of the vibrating machine (1402), and a positioning seat (1404) is arranged on the outer surface of the cleaning machine (1403).
6. The detection device for immunological experiments according to claim 1, wherein: the upper surface of detection case (1) is provided with places board (15), place and be provided with glass board (16) on board (15), place on board (15) offer the lift groove with glass board (16) looks adaptation, the both sides of placing board (15) all are provided with fixed pin (17).
7. The detection device for immunological experiments according to claim 1, wherein: one side of lead screw (5) is provided with follower column (18), one side of sliding block (6) is provided with movable support (19), one side of movable support (19) is provided with fixed strip (20), set up the removal groove with movable support (19) looks adaptation on fixed strip (20), fixed strip (20) are connected with the inner wall of detecting case (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322173182.XU CN220231746U (en) | 2023-08-14 | 2023-08-14 | Detection device for immunology experiments |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322173182.XU CN220231746U (en) | 2023-08-14 | 2023-08-14 | Detection device for immunology experiments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220231746U true CN220231746U (en) | 2023-12-22 |
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ID=89174642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322173182.XU Active CN220231746U (en) | 2023-08-14 | 2023-08-14 | Detection device for immunology experiments |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220231746U (en) |
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2023
- 2023-08-14 CN CN202322173182.XU patent/CN220231746U/en active Active
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