CN220126912U - Cell culture medium integrated treatment system - Google Patents
Cell culture medium integrated treatment system Download PDFInfo
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- CN220126912U CN220126912U CN202321407415.1U CN202321407415U CN220126912U CN 220126912 U CN220126912 U CN 220126912U CN 202321407415 U CN202321407415 U CN 202321407415U CN 220126912 U CN220126912 U CN 220126912U
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- cell culture
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- treatment system
- detected product
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- 239000006143 cell culture medium Substances 0.000 title claims abstract description 47
- 238000001514 detection method Methods 0.000 claims abstract description 28
- 230000001678 irradiating effect Effects 0.000 claims abstract description 3
- 238000002835 absorbance Methods 0.000 claims description 4
- 230000005540 biological transmission Effects 0.000 claims description 4
- 238000002834 transmittance Methods 0.000 claims description 4
- 239000013013 elastic material Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 238000007689 inspection Methods 0.000 description 7
- 230000009471 action Effects 0.000 description 6
- 239000002609 medium Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 238000004113 cell culture Methods 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000010261 cell growth Effects 0.000 description 2
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- 230000004075 alteration Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 208000003464 asthenopia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
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- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a comprehensive treatment system for a cell culture medium, which belongs to the technical field of production of cell culture media and comprises a conveying device, a control device and a control device, wherein the conveying device is used for conveying a to-be-detected product; the second conveying device is arranged in a staggered manner with the first conveying device and is used for conveying the unqualified products; the removing device is used for pushing the to-be-detected product on the first conveying device to the second conveying device after the removing device acts; a light source for irradiating a sample to be inspected; the detection device is used for receiving the light rays emitted by the light source and passing through the to-be-detected product and analyzing the received light rays so as to obtain the appearance characteristics of the to-be-detected product; and the control device is used for controlling the rejecting device to act when the appearance characteristics of the to-be-detected product are judged to not meet the preset threshold value. The utility model not only can reduce the manual participation degree, but also can effectively improve the accuracy and the uniformity of the detection result.
Description
Technical Field
The utility model relates to the technical field of cell culture media, in particular to a comprehensive treatment system for a cell culture medium.
Background
The cell culture medium is a nutrient medium for cell growth and propagation and is prepared from different substances. The cell culture medium simulates the growth environment of cells in vivo, so that the cells can continue to grow and reproduce in vitro and maintain the structure and function of the cells. The cell culture medium has more than hundreds of kinds of components, and can be divided into water, amino acid, vitamins, carbohydrate, inorganic salt and other auxiliary nutrients.
The quality of the cell culture medium directly affects the growth of cells, and strict quality control of the cell culture medium is required to ensure the quality of cell culture. Traditional cell culture medium inspection is monitored manually, and quality of the culture medium is judged according to appearance conditions of the culture medium by visual inspection of quality inspection staff. However, the judging mode of naked eye observation is rough, the error is larger, and long-time manual detection easily causes visual fatigue of quality inspection personnel, so that the probability of false detection and false judgment is further increased.
In addition, when unqualified products of the culture medium are detected, quality inspection personnel are required to manually reject the unqualified products from the production line, so that the workload of the quality inspection personnel is further increased, and the quality inspection accuracy and efficiency of the quality inspection personnel are further reduced.
To solve the above problems, there is currently an apparatus for detecting color (e.g., chromaticity) of a liquid medium, for example, chinese patent publication No. CN111060460a, which discloses an apparatus for color recognition of a liquid medium, which can analyze collected light under the cooperation of a light source to obtain chromaticity of the liquid medium.
Based on the teaching of the above patent technology, for different cell culture mediums, the detection of the cell culture medium can be well performed by setting a color threshold in advance instead of manually, and the detection result (whether qualified) is well ensured in terms of accuracy and uniformity.
Disclosure of Invention
Aiming at the problems of insufficient accuracy and efficiency caused by manual detection of cell culture medium and rejection of unqualified products in the prior art, the utility model aims to provide a comprehensive treatment system for cell culture medium so as to at least partially solve the problems.
In order to achieve the above purpose, the technical scheme of the utility model is as follows:
a cell culture medium comprehensive treatment system comprises
The first conveying device is used for conveying the to-be-detected product;
the second conveying device is arranged in a staggered manner with the first conveying device and is used for conveying the unqualified products;
the removing device is used for pushing the to-be-detected product on the first conveying device to the second conveying device after the removing device acts;
the light source is used for irradiating the to-be-detected product;
the detection device is used for receiving the light rays emitted by the light source and passing through the to-be-detected product and analyzing the received light rays so as to obtain the appearance characteristics of the to-be-detected product;
and the control device is used for controlling the rejecting device to act when the appearance characteristics of the to-be-detected product are judged to not meet the preset threshold value.
Preferably, the device further comprises a shell, the shell is covered at the junction of the first conveying device and the second conveying device, a running channel parallel to the first conveying device and a rejecting channel parallel to the second conveying device are formed on the shell, and the outlines and the sizes of the running channel and the rejecting channel are matched with the to-be-detected product; the light source and the detection device are uniformly distributed on the inner wall of the shell and are symmetrical with respect to the running channel.
Preferably, the removing device comprises a bracket, an air cylinder and a push plate, wherein the bracket is fixed on the shell, the push plate is positioned in the shell, and the moving direction of the push plate is opposite to and parallel to the removing channel.
Preferably, a cushion pad made of elastic materials is fixed on the surface of the push plate.
Preferably, the detection device is a transmission spectrocolorimeter.
Preferably, the appearance characteristic of the sample includes one or more of transmittance, absorbance and chromaticity of the cell culture medium.
Preferably, the light source is a full-band balanced LED light source.
Preferably, the control device is fixedly mounted on the housing.
By adopting the technical scheme, the utility model has the beneficial effects that: according to the utility model, through the arrangement of the light source, the detection device, the control device and the rejecting device, each cell culture medium on the first conveying device can be detected to have the appearance characteristics including parameters such as transmittance, absorbance or chromaticity, and then the control device judges whether the detection value accords with the preset threshold value stored by the detection value, if so, the cell culture medium is qualified, the control device does not respond, otherwise, the control device sends an action instruction to the rejecting device, so that the rejecting device acts to push the cell culture medium which is detected to be unqualified from the first conveying device to the second conveying device, and the finally detected cell culture medium is sent to the next production process by virtue of the first conveying device, and if so, the unqualified cell culture medium is destroyed or reworked from the second conveying device. Compared with the prior art, the cell culture medium comprehensive treatment system provided by the embodiment has low artificial participation degree in the whole working process, and the accuracy and the uniformity of the detection result can be effectively improved.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model;
fig. 2 is a schematic cross-sectional top view of the housing of the present utility model.
In the figure, a first conveying device 1, a second conveying device 2, a shell 3, a light source 4, a detection device 5, a control device 6, a removing device 7, an air cylinder 71 and a push plate 72 are arranged.
Detailed Description
The following describes the embodiments of the present utility model further with reference to the drawings. The description of these embodiments is provided to assist understanding of the present utility model, but is not intended to limit the present utility model. In addition, the technical features of the embodiments of the present utility model described below may be combined with each other as long as they do not collide with each other.
As shown in fig. 1-2, an embodiment of the present utility model provides a cell culture medium integrated treatment system, which includes a first conveying device 1, a second conveying device 2, a housing 3, a light source 4, a detecting device 5, a control device 6, and a rejecting device 7.
The first conveying device 1 is used for conveying to-be-detected products (namely, filled cell culture mediums), and the second conveying device 2 and the first conveying device 1 are arranged in a staggered mode and are used for conveying unqualified products (namely, cell culture mediums with unqualified detection results) removed from the first conveying device 1. In this embodiment, the first conveying device 1 and the second conveying device 2 are configured as belt conveyors, and are arranged in a T-shape, that is, the conveying start point of the second conveying device 2 is connected with the first conveying device 1.
The shell 3 is made of opaque materials, such as stainless steel, the shell 3 is covered at the junction of the first conveying device 1 and the second conveying device 2, the shell 3 is provided with a running channel parallel to the first conveying device 1 and a rejecting channel parallel to the second conveying device 2, and the outlines and the sizes of the running channel and the rejecting channel are matched with the to-be-detected product. In this embodiment, the bottom surface of the housing 3 is open, and three notches extending to the bottom surface thereof are formed on the circumferential side surface, wherein two notches are opposite to each other to form the above-mentioned operation channel (i.e. for the first conveyor 1 to carry cell culture medium therethrough), and the other notch forms the above-mentioned removal channel (i.e. the removal channel does not pass through the housing 3 and can also pass through the second conveyor 2 to carry cell culture medium therethrough).
The light source 4 is fixedly mounted on the inner wall of the housing 3, for example the light source 4 is configured as a full-band balanced LED light source for emitting light for illuminating the article to be inspected. The relatively closed space provided by the housing 3 can avoid the interference of the external environment to the light emitted by the light source 4.
The detection means 5 are also fixedly mounted on the inner wall of the housing 3 and the light source 4 and the detection means 5 are symmetrically arranged about the running channel, while in a height position they are adapted to enable light to be received by the detection means 5 through the object to be inspected. The detecting device 5 is configured to receive light emitted by the light source 4 and passing through the to-be-detected article, and analyze the received light to obtain an appearance characteristic of the to-be-detected article. In this embodiment, the detection device 5 is configured as a transmission spectrocolorimeter, and the appearance characteristics of the to-be-detected product include one or more of transmittance, absorbance and chromaticity of the cell culture medium, so that the user can set the detection items according to the actual situation.
The control device 6 is fixedly mounted on the housing 3, for example, on the top surface, and the control device 6 is connected with the detection device 5 through a transmission line, so that after receiving the appearance characteristic data of the to-be-detected product, the control device 6 compares the appearance characteristic data with a stored preset threshold value, and sends an action instruction to the removing device 7 when judging that the appearance characteristic of the to-be-detected product does not meet the preset threshold value. In this embodiment, the control device 6 is configured as a single-chip microcomputer, which is usually externally connected with a touch screen, so as to facilitate inputting and adjusting a preset threshold value.
The rejecting device 7 is used for pushing the to-be-detected product detected as the defective product on the first conveying device 1 to the second conveying device 2 after receiving the action command. In this embodiment, the removing device 7 includes a cylinder 71 and a push plate 72, the cylinder 71 is fixed on the outer wall of the housing 3, a through hole into which the output end of the cylinder 71 extends is formed in the side wall of the housing 3, the push plate 72 is located inside the housing 3, and the push plate 72 is fixedly connected with the output end of the cylinder 71 extending into the housing 3. It will be appreciated that the push plate 72 is spaced from the second conveyor 2 on either side of the first conveyor 1, and that the direction of movement of the push plate 72 is opposite and parallel to the reject path; meanwhile, the pusher plate 72 and the second conveying device 2 are located on the downstream side of the light source 4 and the detecting device 5. The cylinder controller to which the cylinder 71 is attached is connected to the control device 6 so as to receive an action command for controlling the cylinder 71 to perform a reciprocating action, i.e. the push plate 72 is extended and the defective cell culture medium is pushed onto the second conveying device 2, and the push plate 72 is reset again.
Wherein the surface of the push plate 72 is fixed with a cushion (not shown) made of an elastic material to prevent the push plate 72 from damaging the cell culture medium. And it is understood that in the rejecting device 7, a hydraulic cylinder or an electric push rod may be used instead of the cylinder 71.
The working process of the cell culture medium comprehensive treatment system provided by the embodiment of the utility model is as follows:
when in use, the cell culture medium to be detected is sequentially placed on the first conveying device 1 and sequentially passes through the shell 3 under the drive of the first conveying device 1; during the period, the light emitted by the light source 4 is received by the detection device 5 after passing through the cell culture medium, the appearance characteristic of the cell culture medium is further identified by the detection device 5, then the control device 6 judges whether the appearance characteristic meets the requirement of a preset threshold value, if yes, the control device 6 does not respond, otherwise, the control device 6 sends an action instruction to the removing device 7, so that the removing device 7 acts and the cell culture medium which is detected to be unqualified is pushed onto the second conveying device 2 from the first conveying device 1. Similarly, each cell culture medium is subjected to the above-mentioned process, and the cell culture medium which is finally detected to be qualified is conveyed from the downstream of the first conveying device 1 to the next production process, while the cell culture medium which is detected to be unqualified is conveyed from the second conveying device 2 to other treatment processes such as destruction or reworking. Compared with the prior art, the cell culture medium comprehensive treatment system provided by the embodiment has low artificial participation degree in the whole working process, and the accuracy and the uniformity of the detection result can be effectively improved.
The embodiments of the present utility model have been described in detail above with reference to the accompanying drawings, but the present utility model is not limited to the described embodiments. It will be apparent to those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the utility model, and yet fall within the scope of the utility model. It should be noted that, in the description of the present utility model, the positional or positional relation indicated by the terms such as "upper", "lower", "left", "right", "front", "rear", etc. are merely for convenience of describing the present utility model based on the description of the structure of the present utility model shown in the drawings, and are not intended to indicate or imply that the apparatus or element to be referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present utility model.
The terms "first" and "second" in this technical solution are merely references to the same or similar structures, or corresponding structures that perform similar functions, and are not an arrangement of the importance of these structures, nor are they ordered, or are they of a comparative size, or other meaning.
In addition, unless explicitly stated and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., the connection may be a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two structures. It will be apparent to those skilled in the art that the specific meaning of the terms described above in this application may be understood in the light of the general inventive concept in connection with the present application.
Claims (8)
1. A cell culture medium integrated treatment system, characterized in that: comprising
The first conveying device is used for conveying the to-be-detected product;
the second conveying device is arranged in a staggered manner with the first conveying device and is used for conveying the unqualified products;
the removing device is used for pushing the to-be-detected product on the first conveying device to the second conveying device after the removing device acts;
the light source is used for irradiating the to-be-detected product;
the detection device is used for receiving the light rays emitted by the light source and passing through the to-be-detected product and analyzing the received light rays so as to obtain the appearance characteristics of the to-be-detected product;
and the control device is used for controlling the rejecting device to act when the appearance characteristics of the to-be-detected product are judged to not meet the preset threshold value.
2. The cell culture media integrated treatment system of claim 1, wherein: the device comprises a first conveying device, a second conveying device, a first conveying device and a second conveying device, wherein the first conveying device and the second conveying device are arranged in the first conveying device, the second conveying device is arranged in the second conveying device, the first conveying device and the second conveying device are arranged in the first conveying device, the second conveying device are arranged in the second conveying device, and the first conveying device and the second conveying device are arranged in the second conveying device respectively; the light source and the detection device are uniformly distributed on the inner wall of the shell and are symmetrical with respect to the running channel.
3. The cell culture media integrated treatment system of claim 2, wherein: the removing device comprises a support, an air cylinder and a push plate, wherein the support is fixed on the shell, the push plate is positioned in the shell, and the moving direction of the push plate is opposite to and parallel to the removing channel.
4. A cell culture media integrated treatment system according to claim 3, wherein: the surface of the push plate is fixed with a buffer pad made of elastic materials.
5. The cell culture media integrated treatment system of claim 1, wherein: the detection device is a transmission spectrocolorimeter.
6. The cell culture media integrated treatment system of claim 1, wherein: the appearance characteristics of the to-be-detected product comprise one or more of transmittance, absorbance and chromaticity of a cell culture medium.
7. The cell culture media integrated treatment system of claim 1, wherein: the light source is a full-band balanced LED light source.
8. A cell culture media integrated treatment system according to claim 3, wherein: the control device is fixedly arranged on the shell.
Priority Applications (1)
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CN202321407415.1U CN220126912U (en) | 2023-06-05 | 2023-06-05 | Cell culture medium integrated treatment system |
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CN202321407415.1U CN220126912U (en) | 2023-06-05 | 2023-06-05 | Cell culture medium integrated treatment system |
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CN202321407415.1U Active CN220126912U (en) | 2023-06-05 | 2023-06-05 | Cell culture medium integrated treatment system |
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- 2023-06-05 CN CN202321407415.1U patent/CN220126912U/en active Active
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