CN220010257U - Closed cell preparation partial shipment device - Google Patents
Closed cell preparation partial shipment device Download PDFInfo
- Publication number
- CN220010257U CN220010257U CN202321552359.0U CN202321552359U CN220010257U CN 220010257 U CN220010257 U CN 220010257U CN 202321552359 U CN202321552359 U CN 202321552359U CN 220010257 U CN220010257 U CN 220010257U
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- CN
- China
- Prior art keywords
- cell preparation
- partial shipment
- closed cell
- test tube
- split charging
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- 238000002360 preparation method Methods 0.000 title claims abstract description 39
- 238000003756 stirring Methods 0.000 claims abstract description 31
- 239000007788 liquid Substances 0.000 claims abstract description 11
- 239000006285 cell suspension Substances 0.000 claims abstract description 7
- 230000007246 mechanism Effects 0.000 claims abstract description 7
- 238000007789 sealing Methods 0.000 claims description 13
- 238000002156 mixing Methods 0.000 claims description 4
- 241000894006 Bacteria Species 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims description 3
- 239000000428 dust Substances 0.000 claims description 3
- 229920001971 elastomer Polymers 0.000 claims description 3
- 239000005060 rubber Substances 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 2
- 239000012528 membrane Substances 0.000 claims description 2
- 238000004806 packaging method and process Methods 0.000 claims 2
- 238000001125 extrusion Methods 0.000 abstract description 2
- 238000003780 insertion Methods 0.000 abstract description 2
- 230000037431 insertion Effects 0.000 abstract description 2
- 210000004027 cell Anatomy 0.000 description 22
- 239000011550 stock solution Substances 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 210000002865 immune cell Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model relates to the technical field of medical instruments and discloses a closed cell preparation split charging device which comprises a base, wherein a shell is arranged on the upper surface of the base, a stirring box is arranged inside the shell, a cell suspension input pipe and a frozen storage liquid input pipe are communicated with the top of the stirring box, a head supporting plate is arranged below a stirring blade, an electromagnetic liquid valve is communicated with the bottom of the supporting plate, and a split charging mechanism is arranged below the supporting plate. The cell preparation is opened through the electromagnetic liquid valve and falls down, then the intake pipe is inflated to inside, inside gaseous inflation extrusion baffle downwardly moving, until the inside of partial shipment head insertion test tube, when the baffle contacts the bottom of agitator tank, the gas continues to inflate and opens the piston, with cell preparation through partial shipment head impress in the test tube, stop to inflate after accomplishing, open electromagnetic gas valve exhaust gas, the spring makes the device reset, this design can make the cell preparation automatic partial shipment, automatic partial shipment accelerates partial shipment speed, improve work efficiency.
Description
Technical Field
The utility model relates to the technical field of medical instruments, in particular to a closed cell preparation split charging device.
Background
The cell preparation is a medicine prepared by the steps of cell culture, extraction, purification and the like, is commonly used for treating certain diseases and improving health status, and can be a single cell type preparation such as a monocyte preparation, a lymphocyte preparation, a stem cell preparation and the like; or can be a preparation prepared by mixing multiple cell types, such as immune cell preparation, hematopoietic stem cell preparation, etc.
In chinese patent publication No. CN213553763U, a closed cell preparation dispensing apparatus is disclosed, and the inventors consider that the following drawbacks exist with respect to the related art in the above: above-mentioned prior art is possible partial shipment effect, but adopts manual partial shipment, and efficiency is too low, and the precision of partial shipment can't be guaranteed.
Disclosure of Invention
(one) solving the technical problems
Aiming at the defects of the prior art, the utility model provides a closed cell preparation split charging device which has the advantages of fully mixing cell preparations for automatic and rapid split charging and the like, and solves the problems that the manual split charging is adopted, the efficiency is too low, and the split charging precision cannot be ensured.
(II) technical scheme
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a closed cell preparation partial shipment device, includes the base, the upper surface of base is provided with the casing, the inside of casing sets up and agitator tank, the top fixed mounting of agitator tank has the motor, the output fixedly connected with stirring leaf of motor, the top intercommunication of agitator tank has cell suspension input tube and frozen stock solution input tube, the below of stirring leaf sets up first backup pad, the bottom intercommunication of backup pad has electromagnetic liquid valve, and the below of backup pad is provided with partial shipment mechanism for the partial shipment of mixed back cell preparation, the below of partial shipment mechanism is provided with the test tube correspondingly.
Preferably, the split charging mechanism comprises an electromagnetic air valve, an air inlet pipe and a baffle plate, wherein the electromagnetic air valve and the air inlet pipe are communicated with two sides of the stirring tank, the baffle plate is arranged on the inner wall of the stirring tank, a filter is arranged in the air inlet pipe, the bottom of the baffle plate is communicated with a split charging head, a spring is fixedly connected between the lower surface of the baffle plate and the stirring tank, and a piston is movably connected in the split charging head.
Preferably, a head conveying belt is arranged in the base, and a fixing frame is arranged on the upper surface of the conveying belt and used for placing test tubes.
Preferably, the top seal of test tube has the sealing plug, the sealing plug adopts two semicircular rubber that the top has the recess to make, and sealing plug and partial shipment head be corresponding setting, and after the partial shipment is accomplished, the sealing plug can seal the test tube voluntarily, prevents outside bacterium or dust entering when taking out.
Preferably, the electromagnetic air valve is a one-way air outlet valve, and is used for discharging air when the baffle is reset, the piston can only be opened downwards, and after the air in the stirring tank is discharged, the electromagnetic air valve is automatically closed upwards under the action of negative pressure, so that the cell preparation is prevented from falling during split charging.
Preferably, the aperture of a filtering membrane of the filter is less than or equal to 0.45 mu m, so that external dust and bacteria cannot enter.
(III) beneficial effects
Compared with the prior art, the utility model provides a closed cell preparation split charging device, which has the following beneficial effects:
this closed cell preparation partial shipment device opens through the electromagnetic liquid valve through the cell preparation that mixes and falls, then the air-blower of intake pipe access is to inside aerifing, filter through the filter, inside gaseous inflation extrusion baffle downwardly moving, until the inside of partial shipment head insertion test tube, when the bottom of agitator tank is contacted to the baffle, the piston is opened in gaseous continuous inflation, impress the cell preparation into the test tube through the partial shipment head, stop to aerify after accomplishing, open electromagnetic gas valve exhaust gas, the spring makes the device reset, carry out the work of next round, this design can make the automatic partial shipment of cell preparation, automatic sealing transportation goes out after accomplishing, automatic partial shipment accelerates the partial shipment speed, improve work efficiency.
Drawings
FIG. 1 is a schematic perspective view of the present utility model;
FIG. 2 is a schematic diagram of the internal structure of the present utility model;
fig. 3 is an enlarged schematic view of the structure of fig. 2 a according to the present utility model.
Wherein: 1. a base; 2. a conveyor belt; 3. a fixing frame; 4. a test tube; 5. a motor; 6. stirring the leaves; 7. a cell suspension input tube; 8. a frozen stock solution input pipe; 9. a support plate; 10. an electromagnetic liquid valve; 11. an electromagnetic air valve; 12. an air inlet pipe; 13. a filter; 14. a baffle; 15. split charging heads; 16. a piston; 17. a spring; 18. a housing; 19. a sealing plug; 20. a stirring box.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-3, a closed cell preparation split charging device comprises a base 1, a head conveying belt 2 is arranged in the base 1, a fixing frame 3 is arranged on the upper surface of the conveying belt 2 and used for placing a test tube 4, a sealing plug 19 is sealed at the top of the test tube 4, the sealing plug 19 is made of two semicircular rubbers with grooves at the top, the sealing plug 19 and a split charging head 15 are correspondingly arranged, a shell 18 is arranged on the upper surface of the base 1, a filter 13 is arranged in the shell 18 and a stirring box 20, a motor 5 is fixedly arranged at the top of the stirring box 20, a stirring blade 6 is fixedly connected to the output end of the motor 5, a cell suspension input pipe 7 and a frozen storage liquid input pipe 8 are communicated at the top of the stirring box 20, a head supporting plate 9 is arranged below the stirring blade 6, an electromagnetic liquid valve 10 is communicated at the bottom of the supporting plate 9, an electromagnetic air valve 11, an air inlet pipe 12 and a baffle 14 sliding on the inner wall of the stirring box 20 are respectively, the electromagnetic air valve 11 is a one-way air outlet valve and is used for discharging air when the baffle 14 resets, the piston 16 can only be opened downwards, a filter 13 is arranged in the interior of the air inlet pipe 12, a filter 13 has a pore diameter of 0.45 m, a cell suspension input pipe 7 and a bacterial filter 15 can not enter the bottom of the stirring box 15, and a filter 15 can not enter the stirring head 15, and the filter 15 can not be fixedly connected to the bottom of the stirring head 15, and the filter 15 is connected to the bottom of the stirring head is fixedly connected to the surface of the stirring head 15.
Through the technical scheme, the mixed cell preparation is opened and falls through the electromagnetic liquid valve 10, then the air blower connected with the air inlet pipe 12 charges the inside, the air is filtered through the filter 13, the internal gas expands and extrudes the baffle plate 14 to move downwards until the split charging head 15 is inserted into the test tube 4, when the baffle plate 14 contacts the bottom of the stirring box 20, the gas continuously charges and opens the piston 16, the cell preparation is pressed into the test tube 4 through the split charging head 15, the air charging is stopped after the completion, the electromagnetic air valve 11 is opened to exhaust the gas, and the spring 17 resets the device to perform the next round of work.
Working principle: during operation, suspension and frozen stock solution are added into the stirring box 20 through the cell suspension input pipe 7 and the frozen stock solution input pipe 8, the motor 5 is controlled to drive the stirring blade 6 to rotate, the cell preparation is fully mixed, the electromagnetic liquid valve 10 is opened after the mixing is completed to enable the cell preparation to fall down, then the blower connected with the air inlet pipe 12 inflates the inside, the air is filtered through the filter 13, the internal gas expands and extrudes the baffle 14 to move downwards until the split charging head 15 is inserted into the test tube 4, when the baffle 14 contacts the bottom of the stirring box 20, the gas continuously inflates and opens the piston 16, the cell preparation is pressed into the test tube 4 through the split charging head 15, the inflation is stopped after the completion, the electromagnetic air valve 11 is opened to exhaust the gas, the spring 17 enables the device to reset, the test tube 4 is conveyed by the conveyer belt 2 in the direction of a straight operator after being packaged by the sealing plug 19, and the next round of operation is repeated.
While embodiments of the present utility model have been shown and described, it will be apparent to those of ordinary skill in the art thatIt will be understood that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the spirit and scope of the utility model as defined by the appended claims and their equivalents 。
Claims (6)
1. The utility model provides a closed cell preparation partial shipment device, includes base (1), its characterized in that: the upper surface of base (1) is provided with casing (18), the inside of casing (18) sets up and agitator tank (20), the top fixed mounting of agitator tank (20) has motor (5), the output fixedly connected with stirring leaf (6) of motor (5), the top intercommunication of agitator tank (20) has cell suspension input tube (7) and frozen solution input tube (8), the below of stirring leaf (6) sets up first backup pad (9), the bottom intercommunication of backup pad (9) has electromagnetic liquid valve (10), and the below of backup pad (9) is provided with sub-packaging mechanism for the partial shipment of cell preparation after mixing, the below of sub-packaging mechanism is provided with test tube (4) correspondingly.
2. The closed cell preparation dispensing apparatus according to claim 1, wherein: the split charging mechanism comprises electromagnetic air valves (11) communicated with two sides of a stirring tank (20), an air inlet pipe (12) and a baffle plate (14) sliding on the inner wall of the stirring tank (20), a filter (13) is arranged in the air inlet pipe (12), a split charging head (15) is communicated with the bottom of the baffle plate (14), a spring (17) is fixedly connected between the lower surface of the baffle plate (14) and the stirring tank (20), and a piston (16) is movably connected in the split charging head (15).
3. The closed cell preparation dispensing apparatus according to claim 1, wherein: the inside of base (1) sets up first conveyer belt (2), mount (3) have been placed to the upper surface of conveyer belt (2) for place test tube (4).
4. A closed cell preparation dispensing apparatus according to claim 3, wherein: the top of test tube (4) is sealed has sealing plug (19), sealing plug (19) adopt two semicircular rubber that have the recess in top to make, and sealing plug (19) are corresponding setting with partial shipment head (15).
5. The closed cell preparation dispensing apparatus according to claim 2, wherein: the electromagnetic air valve (11) is a one-way air outlet valve and is used for discharging air when the baffle (14) is reset, and the piston (16) can only be opened downwards.
6. The closed cell preparation dispensing apparatus according to claim 2, wherein: the aperture of the filtering membrane of the filter (13) is less than or equal to 0.45 mu m, so that external dust and bacteria cannot enter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321552359.0U CN220010257U (en) | 2023-06-16 | 2023-06-16 | Closed cell preparation partial shipment device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321552359.0U CN220010257U (en) | 2023-06-16 | 2023-06-16 | Closed cell preparation partial shipment device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220010257U true CN220010257U (en) | 2023-11-14 |
Family
ID=88684625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321552359.0U Active CN220010257U (en) | 2023-06-16 | 2023-06-16 | Closed cell preparation partial shipment device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220010257U (en) |
-
2023
- 2023-06-16 CN CN202321552359.0U patent/CN220010257U/en active Active
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| GR01 | Patent grant |