CN219897703U - Multichannel solution mixing device - Google Patents

Abstract

The utility model relates to the technical field of solution detection and test, in particular to a multichannel solution mixing device. The multichannel solution mixing device comprises a main body, a liquid inlet, a liquid outlet and a plurality of mixing plates. The inlet sets up in one side of main part, and the liquid outlet sets up in the opposite side of inlet in the main part, and branch cistern and test slot have been seted up to the main part, and the inlet is connected to branch cistern, and branch cistern is connected to test slot one end, and the liquid outlet is connected to the other end, and a plurality of mixing boards set gradually in same test slot. Through setting up branch cistern and test slot and promoting the circulation and the mixing of solution, utilize the characteristic of liquid droplet and surface contact angle, improve mixing efficiency, realize quick mixing. The gap between the electrodes is increased through the design of the liquid dividing tank, so that the effect that a plurality of electrodes can be tested simultaneously in a smaller space is achieved.

Description

Multichannel solution mixing device

Technical Field

The utility model relates to the technical field of solution detection and test, in particular to a multichannel solution mixing device.

Background

Implantable sensors capable of real-time monitoring and analyte concentration can convert biochemical reaction signals based on analyte concentration into electrical or optical signals, and are widely used for analyte detection in clinical, environmental, agricultural and biotechnology applications. Analytes that can be measured in clinical analysis of human fluids by implantable sensors include glucose, lactate, uric acid, cholesterol, bilirubin, amino acids, etc., and implantable sensors have the advantage of continuously determining certain important physiological or pathological parameters over time in the body, thereby obtaining a comprehensive and accurate diagnostic analysis.

For an implantable sensor, the rejection reaction of a human body to foreign matters starts from the implantation moment, namely, the non-specific adsorption of protein is firstly carried out, and the protein is wrapped on the surface of an electrode; cells are then attracted by these proteins to chemotaxis, and fiber encapsulation is later formed. For implantable sensors that detect chemical signals (e.g., blood glucose, lactate, potassium ions, etc.), it is desirable that the body's response not block diffusion of the substance being detected. Therefore, before the development stage or the product delivery, the sensor is usually tested, and the performance index of the sensor, or even the performance of the whole test system, is tested by simulating the human body environment in vitro.

Therefore, a large number of performance tests are required in the research and development stage, and often, the implantable sensor has a small volume, and when the implantable sensor is placed in the same solution bottle or tank for performing the simulation test of a plurality of sensors at the same time, signal interference can be generated between the implantable sensor and the solution bottle or tank, so that the real signal cannot be fed back. The solution tank scheme for the current market mainly uses a single input channel to enter a single tank for use, only one sensor can be tested at a time in the mode, and meanwhile, a large amount of waste of solution can be generated when the solution is replaced, and more time is consumed for operation; or a large closed cavity is used, solution is guided by the input of a liquid inlet hole and matched with a plurality of small holes, so that the solution can enter a plurality of solution tanks, and in the process of flowing the solution through the holes (channels), the requirements on the processing of the holes (channels) are extremely harsh, burrs generated by the processing, larger roughness generated when a processing cutter is fed, bubbles are easily generated at corner positions when the large holes and the small holes are connected, and the flowing of the solution is influenced; or a design of opening a cavity and a small hole is adopted, but the design can generate the overflow phenomenon of the solution tank in the process of shunting from a large solution tank to a small solution tank due to the contact angle formed by the material of the used solution tank and the liquid drops; when the solutions are switched, the solution layering phenomenon is easy to occur in the solution tank when different solutions are replaced, so that the test data are uncertain.

There is therefore a need for a multi-channel solution mixing device to solve the above problems.

Disclosure of Invention

The utility model aims to provide a multichannel solution mixing device which can promote solution circulation and uniform mixing and improve the solution mixing effect.

To achieve the purpose, the utility model adopts the following scheme:

the multichannel solution mixing device comprises a main body, a liquid inlet, a liquid outlet and a plurality of mixing plates, wherein the liquid inlet is formed in one side of the main body, the liquid outlet is formed in the other side of the main body, which is opposite to the liquid inlet, a liquid dividing groove and a test groove are formed in the main body, the liquid dividing groove is connected with the liquid inlet, one end of the test groove is connected with the liquid dividing groove, the other end of the test groove is connected with the liquid outlet, and the mixing plates are sequentially arranged in the same test groove.

The liquid separating tank comprises a first liquid separating tank and a second liquid separating tank, at least one first liquid separating tank, two second liquid separating tanks and four test tanks are arranged on the main body, one side of the second liquid separating tank is communicated with the first liquid separating tank, and the other side of the second liquid separating tank is communicated with the test tanks.

Illustratively, a liquid passing trough is arranged between each secondary liquid separating trough and the primary liquid separating trough and between each test trough and the secondary liquid separating trough.

Illustratively, the side wall of the primary liquid dividing tank facing the secondary liquid dividing tank is sloped.

Illustratively, the test slots are provided with four, each two of the test slots communicating with one of the secondary fluid reservoirs.

Illustratively, the side wall of the secondary fluid reservoir facing the test slot is sloped.

Illustratively, no fewer mixing plates are disposed within each of the test slots.

Illustratively, the mixing plate is horizontally provided with a plurality of filtering through holes.

Illustratively, the heights of the filter through holes on two adjacent mixing plates in the same test slot are different in the vertical direction.

Illustratively, the liquid inlet is disposed on an outer sidewall of the main body, and the liquid outlet is disposed on a bottom of the main body.

Illustratively, the heights of the bottoms of the primary liquid-dividing tank, the secondary liquid-dividing tank, and the test tank are sequentially reduced.

Illustratively, the height of the liquid passing trough at the upper stage is higher than that of the liquid passing trough at the lower stage.

Illustratively, three mixing plates are arranged in each test slot, a biosensor to be tested is arranged between the first mixing plate and the second mixing plate, and a temperature sensor is arranged between the second mixing plate and the third mixing plate.

The beneficial effects of the utility model are as follows:

in the multichannel solution mixing device provided by the utility model, the distribution groove and the test groove are arranged to promote the circulation and uniform mixing of the solution, and the characteristics of the contact angle between the liquid drop and the surface are utilized to improve the mixing efficiency and realize rapid mixing. The gap between the electrodes is increased through the design of the liquid dividing tank, so that the effect that a plurality of electrodes can be tested simultaneously in a smaller space is achieved.

Drawings

FIG. 1 is a schematic view of a multi-channel solution mixing device according to the present utility model at one viewing angle;

FIG. 2 is a schematic view of a multi-channel solution mixing device according to the present utility model at another view angle;

fig. 3 is a schematic structural view of the mixing plate provided by the utility model.

In the figure:

100. a main body; 110. a first-stage liquid separating tank; 120. a second-stage liquid separating tank; 130. a test slot; 200. a liquid inlet; 300. a liquid outlet; 400. a mixing plate; 410. a filtering through hole; 500. and a liquid passing groove.

Detailed Description

The technical scheme of the utility model is further described below by the specific embodiments with reference to the accompanying drawings. It is to be understood that the specific embodiments described herein are merely illustrative of the utility model and are not limiting thereof. It should be further noted that, for convenience of description, only some, but not all of the drawings related to the present utility model are shown.

In the present utility model, directional terms, such as "upper", "lower", "left", "right", "inner" and "outer", are used for convenience of understanding and are not to be construed as limiting the scope of the present utility model unless otherwise specified.

In the present utility model, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature.

In the description of the present utility model, unless explicitly stated and limited otherwise, the terms "connected," "connected," and "fixed" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.

As shown in fig. 1 and 2, the multi-channel solution mixing apparatus includes a main body 100, a liquid inlet 200, a liquid outlet 300, and a plurality of mixing plates 400. The inlet 200 sets up in the one side of main part 100, and the liquid outlet 300 sets up in the opposite side of main part 100 inlet 200, and main part 100 has seted up branch cistern and test groove 130, divides the cistern to connect inlet 200, and the liquid outlet 300 is connected to test groove 130 one end connection branch cistern, the other end, and a plurality of mixing boards 400 set gradually in same test groove 130. Through setting up the branch cistern 110 and the test groove 130 and promoting circulation and the misce bene of solution, utilize the characteristic of liquid droplet and surface contact angle, improve mixing efficiency, realize quick mixing. The gap between the electrodes is increased through the design of the liquid dividing tank, so that the effect that a plurality of electrodes can be tested simultaneously in a smaller space is achieved.

Further, the main body 100 in this embodiment is provided with at least one primary liquid-separating tank 110, two secondary liquid-separating tanks 120 and four test tanks 130, one side of the secondary liquid-separating tank 120 is communicated with the primary liquid-separating tank 110, and the other side of the secondary liquid-separating tank 130 is communicated with the test tank 130. Preferably, in this embodiment, one primary liquid separating tank 110 is provided, two secondary liquid separating tanks 120 are provided, and four test tanks 130 are provided. When two secondary liquid tanks 120 are provided and respectively connected to the primary liquid tanks 110, the flow paths of the solutions at different heights can be increased, further enhancing the mixing effect.

Preferably, the bottoms of the primary and secondary liquid dividing tanks 110, 120 and 130 are sequentially lowered in height to ensure smooth flow of the liquid in each stage of the liquid dividing tanks and the test tank, and to improve mixing efficiency thereof.

Further, in this embodiment, a liquid through tank 500 is disposed between each secondary liquid separating tank 120 and the primary liquid separating tank 110, and between each test tank 130 and the secondary liquid separating tank 120. The purpose of the through-liquid tank 500 is to promote the accumulation of solution through its open channels, since the open position of the open channels is substantially under the solution, which will help the solution to pass more easily. Thus, the solution collection efficiency and the flow-through property can be improved, and the solution can be better mixed and treated.

Preferably, the side wall of the primary liquid dividing tank 110 facing the secondary liquid dividing tank 120 in the present embodiment is a slope. This arrangement is to make the solution more smoothly flowing from the primary liquid tank 110 to the secondary liquid tank 120, reduce the resistance of the fluid and the volatilization of the fluid, thereby improving the flow efficiency and reducing the amount of the solution. Meanwhile, the primary liquid separating tank 110 and the secondary liquid separating tank 120 are designed to be beneficial to the flow of the solution and the gradient of the surface area of the solution, so that the mixing efficiency and the fluidity of the solution are further improved. Therefore, the mixing efficiency and fluidity of the multi-channel solution mixing device can be improved, and the solution consumption can be reduced.

Further, the test slots 130 in this embodiment are provided with four, and each two test slots 130 are communicated with one secondary liquid separating slot 120. The arrangement can further improve the mixing efficiency and fluency of the multi-channel solution mixing device, and simultaneously increase the channel quantity of the solutions, so that a plurality of different solutions can be mixed at the same time. When liquid enters the primary liquid tank 110 from the liquid inlet 200, the liquid enters the primary liquid tank 110 first, and then enters the secondary liquid tank 120 through the liquid communication tank 500 connected with the secondary liquid tank 120. Since there are two secondary liquid tanks 120, and one liquid passing tank 500 is provided between each secondary liquid tank 120 and the primary liquid tank 110, the liquid can be split into two liquid passing tanks 500 and respectively enter the secondary liquid tanks 120. Next, liquid will enter the test slot 130 to which it is connected from the secondary liquid tank 120. Each two of the test cells 130 communicate with one of the secondary fluid distribution cells 120 so that fluid can be distributed to and mixed within four different test cells 130. In general, by increasing the number of test slots 130, the mixing of liquids therein may be more complete, while through communication between the plurality of separate tanks, different solutions may be simultaneously mixed in the mixing device, thereby improving mixing efficiency and fluency.

Preferably, in this embodiment, the height of the liquid passing groove 500 located at the upper stage is higher than that of the liquid passing groove 500 located at the lower stage, so as to ensure that the test liquid can flow into the liquid passing groove 500 of the upper stage through the liquid passing groove 500 of the lower stage, and ensure that the flow of the test liquid is more uniform. Further preferably, the height of the liquid passing groove 500 of the first stage is smaller than the height of the whole mixing device groove body, so that the test liquid is prevented from overflowing.

Preferably, the side wall of the secondary fluid reservoir 120 facing the test slot 130 in this embodiment is sloped. The arrangement is favorable for flowing the solution, increasing the surface area of the solution and reducing the dosage of the solution. In particular, the ramp may assist in the rapid flow of solution into the test slot 130, thereby achieving a mixing action. And increasing the surface area of the solution can improve the mixing effect and the reaction rate of the solution and reduce the reaction time. In addition, the cost and the resources can be saved by reducing the consumption of the solution, the reaction rate is quickened, and the consumption of the solution is saved.

Further, three mixing plates 400 are provided in each test slot 130 in the present embodiment. By providing three mixing plates 400 within each test slot 130, the time and path of the mixed liquids through the mixing plates 400 may be increased, thereby improving the uniformity of mixing. In the test, the biosensor and the temperature sensor are arranged between different mixing plates 400, so that the biosensor can be prevented from being influenced by the mixing plate 400 where the temperature sensor is arranged. This may improve the accuracy and reliability of the sensor measurements. Finally, the solution is mixed by the intersection of the holes of the mixing plate 400, so that the mixing process of the liquid can be fully mixed and accelerated, thereby improving the production efficiency and saving the time and the cost.

Specifically, a plurality of filtering through holes 410 are horizontally provided on the mixing plate 400 in the present embodiment. The filtering through holes 410 can form a plurality of small spouts when the solution passes through the mixing plate 400, thereby increasing the surface area of the solution, promoting gas-liquid exchange, further increasing the mixing speed, thus improving the mixing speed and mixing effect and reducing the mixing time.

Further, the height of the filtering through holes 410 on the adjacent mixing plates 400 in the same test slot 130 in the present embodiment is different in the vertical direction. As the solution passes through the mixing plates 400, a change in flow occurs in the vertical direction, thereby increasing the mixing degree of the solution. When the test solution passes through the filter holes 410 of the next mixing plate 400 from the filter holes 410 of the previous mixing plate 400, the test solution can flow up and down to prevent partial substances in the test solution from settling, and the test solution can be fully and uniformly mixed to prevent the different upper and lower layers of the test solution from having different component contents. This effect is more remarkable particularly in the case where the difference in height between the upper and lower filtering through holes 410 is large, so that the mixing effect of the multi-channel solution mixing apparatus can be improved, thereby improving the practicality and performance of the apparatus.

Further, three mixing plates (400) are arranged in each test slot (130) in the embodiment, a biosensor to be tested is arranged between the first mixing plate (400) and the second mixing plate (400), and a temperature sensor is arranged between the second mixing plate (400) and the third mixing plate (400).

Specifically, the liquid inlet 200 in this embodiment is disposed on the outer side wall of the main body 100, and the liquid outlet 300 is disposed on the bottom of the main body 100. The liquid inlet 200 is disposed on the outer side wall of the main body 100, so that liquid can be conveniently input, and the effective space of the main body 100 is not occupied. The liquid outlet 300 is provided at the bottom of the main body 100, and can more sufficiently use gravity to rapidly discharge the mixed liquid, thereby improving mixing efficiency. Meanwhile, the liquid outlet 300 is arranged at the bottom of the main body 100, so that bubbles can be avoided in the liquid outlet process, and the uniformity and stability of the liquid are ensured.

It is to be understood that the above-described embodiments of the present utility model are provided by way of illustration only and not limitation of the embodiments thereof. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. Any modification, equivalent replacement, improvement, etc. which come within the spirit and principles of the utility model are desired to be protected by the following claims.

Claims (10)

1. Multichannel solution mixing arrangement, its characterized in that includes main part (100), inlet (200), liquid outlet (300) and a plurality of mixing board (400), inlet (200) set up in one side of main part (100), liquid outlet (300) set up in on main part (100) inlet (200) opposite side, branch cistern and test groove (130) have been seted up to main part (100), inlet (200) are connected to branch cistern, liquid outlet (300) are connected to test groove (130) one end connection branch cistern, other end, a plurality of mixing board (400) set gradually in same in test groove (130).

2. The multi-channel solution mixing device according to claim 1, wherein the liquid separation tank comprises a first-stage liquid separation tank (110) and a second-stage liquid separation tank (120), at least one of the first-stage liquid separation tank (110), two second-stage liquid separation tanks (120) and four test tanks (130) are arranged on the main body (100), one side of the second-stage liquid separation tank (120) is communicated with the first-stage liquid separation tank (110), and the other side of the second-stage liquid separation tank (120) is communicated with the test tanks (130).

3. The multi-channel solution mixing device according to claim 2, wherein a liquid passing channel (500) is provided between each of the secondary liquid tanks (120) and the primary liquid tank (110) and between each of the test tanks (130) and the secondary liquid tank (120).

4. The multi-channel solution mixing device according to claim 2, wherein a side wall of the primary liquid-dividing tank (110) facing the secondary liquid-dividing tank (120) is sloped, and a side wall of the secondary liquid-dividing tank (120) facing the test tank (130) is sloped.

5. The multi-channel solution mixing device according to claim 2, wherein four of the test cells (130) are provided, and each two of the test cells (130) communicates with one of the secondary liquid tanks (120).

6. The multi-channel solution mixing device according to claim 1, wherein at least two mixing plates (400) are disposed in each test slot (130), a plurality of filtering through holes (410) are horizontally disposed on the mixing plates (400), and the heights of the filtering through holes (410) on two adjacent mixing plates (400) in the same test slot (130) in the vertical direction are different.

7. The multi-channel solution mixing device according to claim 1, wherein the liquid inlet (200) is provided at an outer sidewall of the main body (100), and the liquid outlet (300) is provided at a bottom of the main body (100).

8. The multi-channel solution mixing device according to claim 2, wherein the groove bottom heights of the primary liquid-dividing groove (110), the secondary liquid-dividing groove (120) and the test groove (130) are sequentially reduced.

9. A multi-channel solution mixing device according to claim 3, characterized in that the height of the through-liquid tank (500) at the upper stage is higher than the height of the through-liquid tank (500) at the lower stage.

10. The multi-channel solution mixing device according to claim 5, wherein three mixing plates (400) are disposed in each of the test cells (130), a biosensor to be measured is disposed between a first one of the mixing plates (400) and a second one of the mixing plates (400), and a temperature sensor is disposed between a second one of the mixing plates (400) and a third one of the mixing plates (400).