CN219861305U - Movable in-situ cell uniform distributor - Google Patents

Movable in-situ cell uniform distributor Download PDF

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Publication number
CN219861305U
CN219861305U CN202322461145.9U CN202322461145U CN219861305U CN 219861305 U CN219861305 U CN 219861305U CN 202322461145 U CN202322461145 U CN 202322461145U CN 219861305 U CN219861305 U CN 219861305U
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China
Prior art keywords
plate
plates
storage
driving device
object placing
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CN202322461145.9U
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Chinese (zh)
Inventor
周意祥
刘�东
钟沅沅
李伟
武军政
张航
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Chengdu Rongsheng Pharmaceuticals Co Ltd
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Chengdu Rongsheng Pharmaceuticals Co Ltd
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Priority to CN202322461145.9U priority Critical patent/CN219861305U/en
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Abstract

The utility model relates to the field of biomedical science, and discloses a movable in-situ cell uniform distributor, which comprises a base and a storage plate, wherein the base consists of a bottom plate and two side plates which are oppositely arranged, the middle part of the bottom plate is provided with a hollowed-out hole, and two ends of the side plates are respectively provided with an open chute; the two storage plates are arranged between the two side plates of the base side by side, connecting rods are respectively arranged on two sides of one end, away from each other, of each storage plate, each storage plate is connected in the corresponding sliding groove through the corresponding connecting rods in a sliding mode, one side, close to each other, of one end of each storage plate is detachably connected with the corresponding first fixing assembly, the other side of each storage plate is detachably connected with the corresponding second fixing assembly, the first driving device drives the storage plates to conduct X-direction translational motion through the corresponding first fixing assemblies, and the second driving device drives the storage plates to conduct Y-direction translational motion through the corresponding second fixing assemblies. The utility model can realize uniform distribution of cells, and after the cells are uniformly shaken, the cell plates are directly placed at the fixed positions by pulling the object placing plates, so that the cells do not need to be moved again, and the cell aggregation caused by the movement is avoided.

Description

Movable in-situ cell uniform distributor
Technical Field
The utility model relates to the technical field of biological medical treatment, in particular to a movable in-situ cell uniform distributor.
Background
Cell plating is the basic experimental procedure in biomedical research, i.e. cells are uniformly distributed in a culture dish by shaking them after seeding them on a cell plate. At present, cell plating is mostly manually operated, the uniformity degree of cells depends on the standard degree and experience of operators, subjectivity is strong, vortex is easy to generate in the shaking process, uncertainty exists in the uniformity degree and the full degree of cell tiling in cell plates, and the difference between the plates is large.
In the prior art, some tools for helping researchers to plate more uniformly and instruments for assisting in shaking after plate-plating exist, for example, a cell plate-plating shaking device disclosed in Chinese patent No. 218811634U, and a biological shaking table based on a linear motor and a speed reducer disclosed in Chinese patent No. 213357595U. However, in either form of apparatus, the cell plates need to be hand held in the incubator after shaking. In this process, the cell plate is difficult to keep absolutely stable, and there is often slight rocking back and forth, which just brings the cells closer to the center of the well, which is particularly evident for slower settling cells and large cell clumps, which have accumulated in one place after placement in the incubator.
Disclosure of Invention
In order to solve the defects in the prior art, the utility model provides a movable in-situ cell uniform distributor which does not need to hold a mobile cell plate after shaking.
In order to achieve the technical purpose, the utility model adopts the following technical scheme:
the movable in-situ cell uniform distributor comprises a base and a storage plate, wherein the base consists of a bottom plate and two side plates which are oppositely arranged, the middle part of the bottom plate is provided with a hollowed-out hole, and two ends of each side plate are respectively provided with an open chute; the two storage plates are arranged between the two side plates of the base side by side, connecting rods are respectively arranged on two sides of one end, away from each other, of each storage plate, each storage plate is connected in the corresponding sliding groove through the corresponding connecting rods in a sliding mode, one side, close to each other, of one end of each storage plate is detachably connected with a first fixing assembly, the other side of each storage plate is detachably connected with a second fixing assembly, the first fixing assembly is connected with a first driving device, the first driving device drives the storage plates to conduct X-direction translational motion through the first fixing assemblies, the second fixing assemblies are connected with a second driving device, and the second driving device drives the storage plates to conduct Y-direction translational motion through the second fixing assemblies.
Further, the first fixed subassembly includes first adaptor and two head rods, first drive arrangement is connected through the dead lever to first adaptor one side, has set up two first draw-in grooves along the direction of perpendicular to thing board lateral wall in the first adaptor, and the one end of head rod is equipped with first slider, and two head rods pass through respectively first slider sliding connection is in two of first adaptor in the first draw-in groove, the other end of head rod is with putting the thing board and dismantle and be connected.
Further, the second fixed subassembly includes second connecting rod and second adaptor, second drive arrangement is connected to second connecting rod one end, and the other end is equipped with the second slider, has arranged the second draw-in groove along the direction that is on a parallel with putting the thing board lateral wall in the second adaptor, and second slider sliding connection is in the second draw-in groove, the opposite side of second adaptor is equipped with two transfer poles, and two transfer poles can dismantle with two thing boards of putting respectively and be connected.
Preferably, the first connecting rod is connected with the object placing plate through magnetic attraction, and the switching rod on one side of the second switching piece is connected with the object placing plate through magnetic attraction.
Preferably, the first connecting rod is connected with the object placing plate in an interference inserting and pulling mode, and the switching rod on one side of the second switching piece is connected with the object placing plate in an interference inserting and pulling mode.
Further, the lower part of one end of the two object placing plates, which is close to each other, is provided with a connecting block in a downward extending mode, and the first connecting rod and the switching rod are connected with the connecting block.
Further, the cell plate press device further comprises a press assembly, wherein the press assembly is pressed above the cell plate.
Further, the pressing assembly comprises a pressing plate, the top of the pressing plate is connected with a fixing frame, and the other end of the fixing frame is connected to the top of a side plate of the base through an elastic piece.
Further, the cell plate press comprises a collar, wherein the collar is hollow, an opening is formed in the upper portion of the collar, the collar is placed above the cell plate, and the press plate is placed in the collar.
Further, the elastic piece is a spring.
The utility model has the beneficial effects that:
according to the movable in-situ cell uniform distributor, the first driving device and the second driving device can drive the object placing plate to drive the cell plate to uniformly move, so that uniform cell distribution is realized, after the cells are uniformly shaken, the cell plate is directly placed at a fixed position below the base by pulling the object placing plate, the cell plate does not need to move again, and cell aggregation caused by movement is avoided.
The movable in-situ cell uniform distributor provided by the utility model has the advantages that the first fixing component and the second fixing component are skillfully designed, so that the object placing plate can be ensured to move smoothly when the first driving device or the second driving device works.
In the utility model, the pressing assembly is arranged, so that the stability of the cell plate can be ensured, furthermore, only the lantern ring moves along with the cell plate, the pressing plate does not need to be driven by the driving device without moving, only the friction force between the pressing plate and the lantern ring is overcome, and the stability of the cell plate can be maintained, and the purpose of saving energy can be achieved.
The utility model has simple and compact structure, small whole volume, can be directly used in an incubator with tense space, can be easily moved and is convenient to use.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present utility model and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic overall structure of an embodiment of the present utility model;
FIG. 2 is a schematic view of a base;
FIG. 3 is a schematic illustration of the connection of a first securing assembly;
FIG. 4 is a schematic illustration of the connection of a second securing assembly;
FIG. 5 is a schematic cross-sectional view of the first adapter;
FIG. 6 is a schematic cross-sectional view of FIG. 1;
FIG. 7 is a schematic view showing the state of the cell plate when the storage plate is put flat and is in operation;
FIG. 8 is a schematic view of the position of the cell plate in the tilted state of the storage plate;
FIG. 9 is a schematic view of the cell plate moving downward as the storage plate is pulled outward.
Reference numerals: the device comprises a base, a bottom plate, a 12-side plate, a 13-sliding groove, a 14-hollowed hole, a 2-storage plate, a 21-connecting rod, a 22-connecting block, a 3-first fixing component, a 31-first connecting piece, a 32-first connecting rod, a 33-first clamping groove, a 34-first sliding block, a 35-fixing rod, a 4-first driving device, a 5-second fixing component, a 51-second connecting rod, a 52-second connecting piece, a 53-second sliding block, a 54-second clamping groove, a 55-connecting rod, a 6-second driving device, a 7-cell plate, an 8-pressing component, a 81-pressing plate, a 82-fixing frame, a 83-elastic piece and a 84-collar.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments of the present utility model. The components of the embodiments of the present utility model generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the utility model, as presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
The movable in-situ cell uniform distributor comprises a base 1 and a storage plate 2, wherein the base 1 consists of a bottom plate 11 and two opposite side plates 12, the middle part of the bottom plate 11 is provided with a hollowed-out hole 14, and two ends of the side plates 12 are respectively provided with an open chute 13; the two storage boards 2 are arranged between the two side boards 12 of the base 1 side by side, connecting rods 21 are respectively arranged on two sides of one end, away from each other, of the two storage boards 2, the connecting rods 21 are slidably connected in the sliding grooves 13, one side of one end, close to each other, of each storage board 2 is detachably connected with the first fixing component 3, the other side of each end is detachably connected with the second fixing component 5, the first fixing component 3 is connected with the first driving device 4, the first driving device 4 drives the storage boards 2 through the first fixing component 3 to perform X-direction translational motion, the second fixing component 5 is connected with the second driving device 6, and the second driving device 6 drives the storage boards 2 through the second fixing component 5 to perform Y-direction translational motion.
The first fixing assembly 3 is shown in fig. 3 and 5, and includes a first adapter 31 and two first connecting rods 32, one side of the first adapter 31 is connected with the first driving device 4 through a fixing rod 35, two first clamping grooves 33 are distributed in the first adapter 31 along a direction perpendicular to the sidewall of the object placing plate 2, one end of each first connecting rod 32 is provided with a first sliding block 34, the two first connecting rods 32 are respectively connected in the two first clamping grooves 33 of the first adapter 31 through the first sliding blocks 34 in a sliding manner, and the other end of each first connecting rod 32 is detachably connected with the object placing plate 2. Preferably, the first driving device 4 is a reciprocating linear motor, an output shaft of the first driving device 4 is vertically connected with the fixing rod 35, the first driving device 4 does work to drive the first fixing assembly 3 to reciprocate along the X direction to drive the object placing plate 2 to reciprocate along the X direction, and meanwhile, when the second driving device 6 drives the object placing plate 2 to perform the Y-direction translational motion, the first sliding block 34 at one end of the first connecting rod 32 can slide in the Y direction in the first transferring piece 31.
The second fixing assembly 5 is shown in fig. 4, and comprises a second connecting rod 51 and a second adapter 52, one end of the second connecting rod 51 is connected with the second driving device 6, the other end of the second connecting rod is provided with a second sliding block 53, a second clamping groove 54 is arranged in the second adapter 52 along the direction parallel to the side wall of the object placing plate 2, the second sliding block 53 is slidably connected in the second clamping groove 54, two adapter rods 55 are arranged on the other side of the second adapter 52, and the two adapter rods 55 are detachably connected with the two object placing plates 2 respectively. Preferably, the second driving device 6 is a reciprocating linear motor, an output shaft of the second driving device 6 is coaxially arranged with the second connecting rod 51, the second driving device 6 does work to drive the second fixing assembly 5 to reciprocate along the Y direction, and drives the object placing plate 2 to reciprocate along the Y direction, meanwhile, when the first driving device 4 drives the object placing plate 2 to perform X-direction translational motion, the object placing plate 2 drives the second adapter 52 to move, and the second slider 53 at one end of the second connecting rod 51 slides in the second adapter 52 along the X direction.
Preferably, the first connecting rod 32 is magnetically connected with the storage plate 2 or in interference plug connection with the storage plate 2 by the switching rod 55 on one side of the second switching piece 52, so that the connection and the disassembly are convenient. Further, the connecting block 22 is extended downward from the lower part of the end of the two object placing plates 2, which is close to each other, and the first connecting rod 32 and the switching rod 55 are connected with the connecting block 22. The connection block 22 can reduce the distance between the storage plate 2 and the bottom surface of the base 1.
Further, as shown in fig. 1 and 6, the cell plate device further comprises a pressing assembly 8, wherein the pressing assembly 8 is pressed above the cell plate 7, so that the stability of the cell plate 7 is maintained. Further, the pressing assembly 8 comprises a pressing plate 81, the top of the pressing plate 81 is connected with a fixing frame 82, and the other end of the fixing frame 82 is connected to the top of the side plate 12 of the base 1 through an elastic piece 83; the cell plate also comprises a collar 84, wherein the collar 84 is hollow, an opening is arranged at the upper part of the collar 84, the collar 84 is arranged above the cell plate 7, and the pressing plate 81 is arranged in the collar 84. Under the action of the first driving device or the second driving device, the cell plate 7 shakes, and the lantern ring 84 follows the cell plate 7 to shake synchronously and keep relative static with the cell plate 7; the pressing plate 81 is kept in a fixed position without shaking along with the cell plate 7, and the collar 84 moves relative to the pressing plate 81. By adopting the pressing assembly with the structure, when the pressing assembly shakes, the pressing plate 81 does not need to be driven to synchronously move, and the stability of the cell plate 7 can be maintained and the purpose of energy saving can be achieved only by overcoming the friction force between the pressing plate 81 and the lantern ring 84.
When the cell plate 7 is used, the object placing plate 2, the base 1 and the driving device are firstly installed, then the cell plate 7 is integrally placed in the incubator, the cell plate 7 is placed above the object placing plate 2, the first driving device 4 or the second driving device 6 is started, the cell plate 7 uniformly shakes along with the object placing plate 2, after the shaking is finished, the first fixing component 3 is disconnected from the object placing plate 2, the second fixing component 5 is connected with the object placing plate 2, at the moment, the object placing plate 2 is in a slope shape with one side supported, then the object placing plate 2 is slowly pulled out along the sliding groove 13, the cell plate 7 can slide downwards along the object placing plate 2 in a non-steep descending mode, finally the cell plate 7 stably falls in the incubator through the hollowed-out hole 14 on the bottom plate 11 of the base 1, and finally the base 1 is integrally taken out. Fig. 7, 8 and 9 show schematic diagrams of the storage plate and the cell plate in different states, respectively, so that the downward movement process of the cell plate 7 during the movement process of the storage plate 2 can be shown. The height of the object placing plate 2 from the bottom surface of the base 1 is smaller, so that the shaking of the cell plate 7 during release can be reduced, and the cell plate can be stably placed in the incubator.
Of course, the present utility model is capable of other various embodiments and its several details are capable of modification and variation in light of the present utility model by one skilled in the art without departing from the spirit and scope of the utility model as defined in the appended claims.

Claims (10)

1. A movable in-situ cell uniform distributor, which is characterized in that: the base consists of a bottom plate and two opposite side plates, the middle part of the bottom plate is provided with a hollowed-out hole, and two ends of each side plate are respectively provided with an open chute; the two storage plates are arranged between the two side plates of the base side by side, connecting rods are respectively arranged at two sides of one end, away from each other, of each storage plate, each storage plate is connected in the corresponding sliding groove through the corresponding connecting rod in a sliding manner, one side of one end, close to each other, of each storage plate is detachably connected with the first fixing assembly, the other side of the other end of each storage plate is detachably connected with the second fixing assembly, and the cell plates are placed above the storage plates; the first fixed component is connected with the first driving device, the first driving device drives the object placing plate to perform X-direction translational motion through the first fixed component, the second fixed component is connected with the second driving device, and the second driving device drives the object placing plate to perform Y-direction translational motion through the second fixed component.
2. The mobile in situ cell uniformity distributor according to claim 1, wherein: the first fixed subassembly includes first adaptor and two head rods, first drive arrangement is connected through the dead lever to first adaptor one side, has set up two first draw-in grooves along the direction of perpendicular to thing board lateral wall in the first adaptor, and the one end of head rod is equipped with first slider, and two head rods pass through respectively first slider sliding connection is in two of first adaptor in the first draw-in groove, the other end of head rod can dismantle with putting the thing board and be connected.
3. The mobile in situ cell uniformity distributor according to claim 2, wherein: the second fixing component comprises a second connecting rod and a second adapter, one end of the second connecting rod is connected with the second driving device, the other end of the second connecting rod is provided with a second sliding block, a second clamping groove is arranged in the second adapter along the direction parallel to the side wall of the storage plate, the second sliding block is slidably connected in the second clamping groove, two adapter rods are arranged on the other side of the second adapter, and the two adapter rods are detachably connected with the two storage plates respectively.
4. A mobile in situ cell uniformity distributor according to claim 3 wherein: the first connecting rod is connected with the object placing plate through magnetic attraction, and the switching rod on one side of the second switching piece is connected with the object placing plate through magnetic attraction.
5. A mobile in situ cell uniformity distributor according to claim 3 wherein: the first connecting rod is in interference plug connection with the object placing plate and the switching rod on one side of the second switching piece.
6. The mobile in situ cell uniformity distributor according to claim 5, wherein: the lower part of one end of the two object placing plates, which is close to each other, is provided with a connecting block in a downward extending way, and the first connecting rod and the switching rod are connected with the connecting block.
7. The mobile in situ cell uniformity distributor according to claim 1, wherein: the cell plate press device further comprises a press assembly, wherein the press assembly is pressed above the cell plate.
8. The mobile in situ cell uniformity distributor according to claim 7, wherein: the pressing assembly comprises a pressing plate, the top of the pressing plate is connected with a fixing frame, and the other end of the fixing frame is connected to the top of a side plate of the base through an elastic piece.
9. The mobile in situ cell uniformity distributor according to claim 8, wherein: the pressing assembly further comprises a lantern ring, the lantern ring is hollow, an opening is formed in the upper portion of the lantern ring, the lantern ring is placed above the cell plate, and the pressing plate is placed in the lantern ring.
10. The mobile in situ cell uniformity distributor according to claim 8, wherein: the elastic piece is a spring.
CN202322461145.9U 2023-09-11 2023-09-11 Movable in-situ cell uniform distributor Active CN219861305U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202322461145.9U CN219861305U (en) 2023-09-11 2023-09-11 Movable in-situ cell uniform distributor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202322461145.9U CN219861305U (en) 2023-09-11 2023-09-11 Movable in-situ cell uniform distributor

Publications (1)

Publication Number Publication Date
CN219861305U true CN219861305U (en) 2023-10-20

Family

ID=88331960

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202322461145.9U Active CN219861305U (en) 2023-09-11 2023-09-11 Movable in-situ cell uniform distributor

Country Status (1)

Country Link
CN (1) CN219861305U (en)

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