CN219814177U - Sample collection and pretreatment device - Google Patents
Sample collection and pretreatment device Download PDFInfo
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- CN219814177U CN219814177U CN202321252024.7U CN202321252024U CN219814177U CN 219814177 U CN219814177 U CN 219814177U CN 202321252024 U CN202321252024 U CN 202321252024U CN 219814177 U CN219814177 U CN 219814177U
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- 238000007789 sealing Methods 0.000 claims abstract description 16
- 239000007788 liquid Substances 0.000 claims abstract description 10
- 238000001914 filtration Methods 0.000 claims abstract description 6
- 239000013013 elastic material Substances 0.000 claims abstract description 5
- 230000007423 decrease Effects 0.000 claims description 2
- 238000007781 pre-processing Methods 0.000 claims 9
- 210000003296 saliva Anatomy 0.000 abstract description 18
- 238000001514 detection method Methods 0.000 abstract description 10
- 239000012530 fluid Substances 0.000 abstract description 7
- 210000005239 tubule Anatomy 0.000 abstract description 6
- 238000001125 extrusion Methods 0.000 abstract description 3
- 229920000742 Cotton Polymers 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 102000005348 Neuraminidase Human genes 0.000 description 2
- 108010006232 Neuraminidase Proteins 0.000 description 2
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethyl mercaptane Natural products CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 2
- 206010035737 Pneumonia viral Diseases 0.000 description 1
- 206010062106 Respiratory tract infection viral Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012531 culture fluid Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000009461 vacuum packaging Methods 0.000 description 1
- 208000009421 viral pneumonia Diseases 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The utility model discloses a sample collection and pretreatment device, which mainly comprises a device main body, a sample collection piece and a device main body sealing piece. The device main part is hollow cylinder, and its upper segment is provided with the part of being connected with sample collection spare can dismantle, and the middle section is used for holding sample treatment fluid, is fixed with the non return piece between upper segment and the middle section, and the lower segment is the tubule of downwardly extending, is fixed with filtering element between the middle section of device main part and the lower segment. The device body seals include seals that removably seal the upper and lower sections of the device body, and may temporarily seal the device body after a sample is collected. And the device main body is made of transparent elastic materials, and can directly drop out a liquid drop-shaped saliva sample after extrusion, so that the detection efficiency is improved.
Description
Technical Field
The utility model belongs to the technical field of medical instruments, and particularly relates to a sample acquisition and pretreatment device.
Background
In the course of pathogen detection, sample collection, etc., it is often necessary to collect a sample of a subject, such as a saliva sample, with a sample collector. For example, in the diagnosis of viral respiratory infections or viral pneumonia, the etiology of the analysis can be examined by collecting saliva samples to isolate the virus.
The saliva collection device that currently widely used all adopts stereoplasm transparent body, plastics funnel and upper cover, for example utility model patent CN213129585U discloses a saliva collector, including collection cup and save the pipe, collection cup is from last to including collection section, changeover portion and linkage segment down in proper order, and linkage segment lower extreme is connected with save the pipe upper end, and the upper end of collection section is provided with the notch portion.
However, the device needs to pour saliva out of the nozzle during subsequent detection, can not form droplet saliva, can not be directly filtered, and is inconvenient.
Disclosure of Invention
In order to solve the above problems, the present utility model provides a sample collection and pretreatment device that can improve collection and treatment efficiency and form a droplet-shaped sample liquid.
In order to at least achieve one of the above purposes, the present utility model adopts the following technical scheme:
a sample collection and pretreatment device mainly comprises a device main body, a sample collection member and a device main body sealing member,
the device body is a hollow cylinder, the upper section of the device body is provided with a part which is detachably connected with the sample collecting part, the middle section of the device body is used for containing sample treatment fluid, a non-return part is fixed between the upper section and the middle section of the device body, the lower section of the device body is a tubule which extends downwards, a filtering part is fixed between the middle section and the lower section of the device body,
the sample collecting piece comprises a sample collecting part and a connecting part, the connecting part is provided with a structure which is detachably connected with the upper section of the device main body,
the device body seals include seals that removably seal the upper and lower sections of the device body.
Further, the sample collection part is funnel-shaped, and the connecting part is a pipe part with a funnel extending downwards.
Further, the device body seal is directly removably attached to the lower section of the device body.
Further, the sample collection and pretreatment device further comprises a hollow tube capable of accommodating the device body, the upper end of the hollow tube is in interference fit with the upper section of the device body, and the sealing element of the device body is detachably connected with the lower end of the hollow tube to seal the lower section of the device body.
Further, the detachable connection adopts integrated connection, threaded connection or interference fit connection, so that sealing and detachable connection are realized.
Further, the device body seal is a cap having a threaded structure. Preferably, the device body sealing member includes a lower cover detachably connected to a lower section of the device body or a lower end of the hollow tube, and an upper cover detachably connected to an upper section of the device body or an upper end of the hollow tube.
Further, the outer edge of the upper cover is provided with anti-skid patterns.
Further, a sample processing liquid is pre-contained in a hollow portion of the middle tube body of the device main body below the check member.
Further, the sample is derived from saliva, urine, serum, culture fluid and tissue grinding fluid, preferably, the sample is derived from saliva, the sample treatment fluid is saliva treatment fluid, and the sample treatment fluid is prepared by adding sialidase, wherein mercaptoethanol is added to improve the oxidation resistance.
Further, the sample collection and pretreatment device is a saliva collection and pretreatment device.
Further, the inner diameter of the thin tube is gradually reduced from top to bottom, and preferably, the minimum inner diameter of the thin tube is 1-20mm.
Further, the filter element is a micron-sized filter screen, preferably the filter element has a screen pore size of 10-50 μm.
Further, a cock is provided at the upper end of the filter member to store the sample in the middle section of the device body. When detection is needed, the rotary plug is opened, and the sample treated by the treatment liquid flows into the lower section of the device main body through the filtering component.
Further, the outer surface of the device main body is marked with scales, so that a inspector can quantitatively drip out a sample.
Further, the device body and/or the hollow tube are made of a transparent elastic material.
Further, the outer edge of the upper cover is provided with anti-skid patterns, so that a tested person can conveniently fasten the upper cover, and the tightness is ensured.
Further, the sample collection and pretreatment apparatus may further comprise a packaging member.
The sample collection member may be connected to the device body and then placed in the packaging member, or may be disconnected from the device body and placed in the packaging member alone.
Further, the packing member includes any packing member such as a vacuum packing bag.
The beneficial effects of the utility model are as follows:
1) The lower end of the device main body is provided with the tubule, and the device is made of transparent elastic materials, so that a drip saliva sample can be directly dripped after extrusion, and the detection efficiency is greatly improved;
2) The sample inlet and the sample outlet of the device are respectively arranged at different positions, so that the sample cannot flow backwards, and pollution is avoided;
3) The device comprises sample collection and pretreatment, is completed in one step, can be directly used for detection without additionally treating the sample, saves cost and improves detection efficiency;
4) The utility model does not need to collect the cotton swab, has large sample collection amount, can not cause uncomfortable feeling of the cotton swab to the human body, and reduces the defect that the residual sample on the cotton swab can not be fully mixed.
5) The utility model adds the filter element in the tube body, which can directly filter the sample when dropping out.
Drawings
FIG. 1 is a schematic perspective view of a sample collection and pretreatment apparatus according to the present utility model;
FIG. 2 is a cross-sectional view of a sample acquisition and pretreatment apparatus of the present utility model;
FIG. 3 is a schematic perspective view showing a state that a sample collection and pretreatment apparatus of the present utility model is assembled with a cover;
FIG. 4 is a schematic view of the structure of the swirl plug in the assembly of the sample collection and pretreatment apparatus of the present utility model;
FIG. 5 is a schematic perspective view of a sample collection and pretreatment apparatus of the present utility model assembled with a hollow tube;
the components in the figures are labeled as follows: 1-device body, 101-check, 102-tubule, 103-filter element, 104-stopcock, 2-sample collection element, 201-sample collection portion, 202-connection portion, 3-device body seal, 301-upper lid, 302-lower lid, 4-hollow tube.
Detailed Description
The advantages and features of the present utility model will become more apparent from the following description when taken in conjunction with the accompanying drawings. It should be understood that the embodiments are illustrative only and should not be taken as limiting the scope of the utility model.
It should be noted that, in the claims of the present document, the terms "upper", "lower", "front", "rear", and the like refer to the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are not necessarily to be construed as necessarily referring to the device or component having a particular orientation, configuration, or operation in a particular orientation.
In the present utility model, unless explicitly specified and limited otherwise, the terms "fixedly attached," "connected," and the like are to be construed broadly and, for example, as a fixed connection, as a removable connection, or as a unit; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.
The utility model is further described below with reference to the accompanying drawings.
Fig. 1 and 4 show a specific structure of the sample collection and pretreatment apparatus of the present utility model and an internal structure of an apparatus main body.
The utility model mainly comprises a device main body 1, a sample collecting piece 2 and a device main body sealing piece 3. The device main part 1 is hollow cylinder, and the upper segment of device main part 1 is provided with the part of being connected with the sample collection piece can be dismantled, and the middle section of device main part 1 is used for holding sample treatment fluid, is fixed with check 101 between the upper segment of device main part 1 and the middle section, and the lower segment of device main part 1 is downwardly extending's tubule 102, and the surface mark of device main part 1 has the scale, can be convenient for the inspector ration drip out the sample.
The sample collection member 2 includes a sample collection portion 201 and a connection portion 202, the connection portion 202 is provided with a structure detachably connected to the upper section of the apparatus main body 1, the sample collection portion 201 is funnel-shaped, and the connection portion 202 is a tube portion extending downward from the funnel. The sample processing liquid is pre-contained in the middle tube cavity portion of the apparatus main body 1 below the check member 102.
The device main body sealing member 3 is a cover body with a threaded structure, the device main body sealing member 3 comprises sealing members of an upper section and a lower section of the detachable sealing device main body 1, namely an upper cover 301 and a lower cover 302, the upper cover 301 and the lower cover 302 are connected to the upper section and the lower section of the device main body 1 in an interference fit mode, anti-skidding lines are arranged on the outer edge of the upper cover 301, the upper cover 301 is conveniently fastened by a tested person, and the tightness is guaranteed.
In another alternative embodiment, the device body seal 3 is removably connected to the device body 1 by a threaded connection.
It should be noted that, the inner diameter of the tubule 102 gradually decreases from top to bottom, and the device body 1 is made of transparent elastic material, so that the saliva sample can be directly dripped after extrusion, thereby greatly improving the detection efficiency.
The filter member 103 is fixed inside the tube body of the tubule 102, and can directly filter the sample when dropping out, and the filter member 103 is a micron-sized filter screen, so that a clean saliva sample can be filtered out.
In this embodiment, the filter member 103 has a mesh size of 20 μm, and the sample treatment liquid is prepared by adding sialidase to the treatment liquid, and mercaptoethanol may be added to improve oxidation resistance.
The upper end of the filter 103 may be fixed with a swirl plug 104, as shown in fig. 4, and the swirl plug 104 may ensure that the sample is stored in the middle section of the device body 1 when closed, and the sample flows into the lower end after being rotated and opened, and drops out after being filtered by the filter 103.
Fig. 5 shows a specific structure of the sample collection and pretreatment apparatus of the present utility model in a state of loading the upper cover. As shown in fig. 4, the present utility model further comprises a hollow tube 4 capable of accommodating the device body 1, wherein the upper end of the hollow tube 4 is in interference fit with the upper section of the device body 1, and the device body sealing member 3 is detachably connected with the lower end of the hollow tube 4 to close the lower section of the device body 1.
In order to better understand the technical scheme of the utility model, the following uses the saliva sample for gene detection by the testee as an example:
1) The testee takes out the device main part by oneself, opens the upper cover, installs the upper end at the device main part with sample collection spare and fastening, directly gathers saliva.
2) After saliva is fully collected, the sample collection piece is unscrewed and properly discarded, and the upper cover is mounted at the upper end of the device main body and fastened and delivered to a detection personnel.
3) When the sample is used for detecting, a detecting personnel opens the cock and the lower cover, the device main body is slowly pressed, and saliva sample flows into the lower section from the middle section of the device main body through the filtering device and is extruded in a drop shape.
The above description is only of the preferred embodiments of the present utility model and is not intended to limit the present utility model, and various modifications and variations may be made to the present utility model by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model should be included in the protection scope of the present utility model.
Claims (10)
1. A sample collection and pretreatment device, characterized in that: the sample collection and pretreatment device mainly comprises a device main body (1), a sample collection piece (2) and a device main body sealing piece (3);
the device comprises a device body (1), a sample collecting part, a sample processing liquid, a check part (101) and a filtering part (103), wherein the device body (1) is a hollow cylinder, the upper section of the device body (1) is provided with a part which is detachably connected with the sample collecting part, the middle section of the device body (1) is used for containing the sample processing liquid, the check part (101) is fixed between the upper section and the middle section of the device body (1), the lower section of the device body (1) is a thin pipe (102) which extends downwards, and the filtering part (103) is fixed between the middle section and the lower section of the device body (1);
the sample collection member (2) comprises a sample collection part (201) and a connecting part (202), the connecting part (202) is provided with a structure which is detachably connected with the upper section of the device main body (1),
the device body seal (3) comprises seals for detachably sealing the upper and lower sections of the device body (1).
2. The sample acquisition and pre-processing device of claim 1, wherein: the inner diameter of the thin tube gradually decreases from top to bottom.
3. The sample acquisition and pre-processing device of claim 1, wherein: the sample collection part (201) is funnel-shaped, and the connecting part (202) is a pipe part with a funnel extending downwards.
4. The sample acquisition and pre-processing device of claim 1, wherein: the device body seal (3) is directly detachably connected to the lower section of the device body (1).
5. The sample acquisition and pre-processing device of claim 1, wherein: the sample collection and pretreatment device further comprises a hollow tube (4) capable of accommodating the device body (1), the upper end of the hollow tube (4) is in interference fit with the upper section of the device body (1), and the device body sealing piece (3) is detachably connected with the lower end of the hollow tube (4) to seal the lower section of the device body (1).
6. The sample acquisition and pre-processing device of any one of claims 3-5, wherein: the detachable connection adopts integrated connection, threaded connection or interference fit connection, thereby realizing sealing and detachable connection.
7. The sample acquisition and pre-processing device of claim 1, wherein: the sample processing liquid is pre-contained in the cavity part of the middle tube body of the device main body (1) below the non-return piece (101).
8. The sample acquisition and pre-processing device of claim 1, wherein: a cock (104) is provided at the upper end of the filter member (103).
9. The sample acquisition and pre-processing device of claim 1 or 5, wherein: the device body (1) and/or the hollow tube (4) are made of transparent elastic material.
10. The sample acquisition and pre-processing device of claim 1, wherein: the device main body sealing piece (3) is a cover body with a threaded structure and comprises an upper cover (301) and a lower cover (302), and anti-skid threads are arranged on the outer edge of the upper cover (301).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321252024.7U CN219814177U (en) | 2023-05-23 | 2023-05-23 | Sample collection and pretreatment device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321252024.7U CN219814177U (en) | 2023-05-23 | 2023-05-23 | Sample collection and pretreatment device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219814177U true CN219814177U (en) | 2023-10-13 |
Family
ID=88278845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321252024.7U Active CN219814177U (en) | 2023-05-23 | 2023-05-23 | Sample collection and pretreatment device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219814177U (en) |
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2023
- 2023-05-23 CN CN202321252024.7U patent/CN219814177U/en active Active
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