CN219729114U

CN219729114U - Cooling device for cell storage

Info

Publication number: CN219729114U
Application number: CN202320254820.8U
Authority: CN
Inventors: 王战涛; 贺西京; 王瑞; 宋浚涵; 高飞
Original assignee: Shaanxi Dejian Zhongpu Biotechnology Co ltd
Current assignee: Shaanxi Dejian Zhongpu Biotechnology Co ltd
Priority date: 2023-02-20
Filing date: 2023-02-20
Publication date: 2023-09-22
Anticipated expiration: 2033-02-20

Abstract

The utility model relates to a cooling device for cell storage, which comprises a box body, wherein a cooling chamber and a storage chamber are arranged in the box body, a box cover is arranged at the upper end of the storage chamber, an opening is formed in the box cover, a cover body is hinged on the box cover, one end of the cover body is fixedly connected with the box cover through a bolt, a limiting ring is arranged in the storage chamber, a rotary table is rotatably connected onto the limiting ring, four placing holes are uniformly formed in the rotary table, four lifting rings are movably arranged on the rotary table, four lifting rods are symmetrically arranged at the lower end of each lifting ring, the lower ends of the two lifting rods penetrate through the rotary table and are connected with a placing disc, a driving chamber is arranged in the box body, a first electric push rod is arranged in the driving chamber, and the driving end of the first electric push rod penetrates through the driving chamber and extends into the storage chamber and is connected with a pushing plate, so that when a single test tube is conveniently taken out, the influence on the quality of stem cells is reduced, the stem cells in the test tube can be uniformly mixed with frozen liquid when the liquid is circularly refrigerated, and the effect of a freezing protective agent is improved.

Description

Cooling device for cell storage

Technical Field

The utility model relates to the technical field of cell storage, in particular to a cooling device for cell storage.

Background

Stem cells are a class of pluripotent cells with self-renewing ability that can differentiate into a variety of functional cells under certain conditions. Stem cells need heat sink to store at a low temperature, and some existing heat sinks are in the use, are full of nitrogen gas in the box, and when needs take out single test tube from the box in, nitrogen gas can overflow in a large number from the case mouth to other test tubes that have stem cells in the box all expose in the external world, thereby external bacterium enters into the test tube easily and influences the quality of stem cells, thereby simultaneously a large amount of nitrogen gas that overflows from the case mouth frostbite staff easily, very unsafe.

Secondly, in order to protect the cells from being damaged in the freezing and thawing processes, a freezing solution containing a freezing protective agent is generally added into a test tube for storing the stem cells, and the existing cooling device for cell storage is inconvenient to uniformly mix the stem cells with the freezing solution in the cooling process of the stem cells, so that the effect of the freezing protective agent is reduced.

Disclosure of Invention

(one) solving the technical problems

Aiming at the defects of the prior art, the utility model provides a cooling device for cell storage, which solves the problem that when a single test tube is required to be taken out from a box body in the use process of the existing cooling device, other test tubes with stem cells in the box are exposed to the outside, and external bacteria are easy to enter the test tubes, so that the quality of the stem cells is affected.

(II) technical scheme

In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a cell is stored and is used heat sink, includes the box, be equipped with cooling chamber and apotheca in the box, be equipped with the cooling subassembly in the cooling chamber, the apotheca upper end is equipped with the case lid, the case lid passes through a plurality of bolts and box fixed connection, be equipped with the opening on the case lid, articulated the connection has the lid on the case lid, lid one end passes through bolt and case lid fixed connection, be equipped with the spacing ring in the apotheca, it is connected with the carousel to rotate on the spacing ring, evenly be equipped with four placement holes on the carousel, the activity is equipped with four lifting rings on the carousel, every lifting ring lower extreme symmetry is equipped with four lifter, two the lifter lower extreme passes the carousel and is connected with the placement tray, be equipped with the drive chamber in the box, be equipped with first electric putter in the drive chamber, first electric putter drive end stretches into the apotheca and is connected with the impeller, the carousel lower extreme is equipped with rotating assembly, rotating assembly is including setting up the bull stick under the carousel, is convenient for avoid other test tubes to expose in the external world when taking out single test tube to reduce the influence on the frostbite quality of the cell of work personnel simultaneously.

In a further preferred embodiment, the lower end of the box body is slidably connected with a driving ring through a track structure, the driving ring is movably sleeved on the outer side of the rotating rod, a second electric push rod is arranged at the lower end of the box body, and the driving end of the second electric push rod is connected with the driving ring so as to facilitate the movement of the driving ring.

In a further preferred embodiment, the lower end of the driving ring is provided with a motor, the driving end of the motor is provided with a driving gear, the lower end of the rotating rod penetrates through the box body to be connected with a driven gear, and the driving gear is meshed with the driven gear to facilitate the rotation of the driven gear.

In a further preferred embodiment, a third electric push rod is arranged at the lower end of the driving ring, a rack matched with the driven gear is arranged at the driving end of the third electric push rod, and the rack is in sliding connection with the driving ring through a track structure so as to facilitate the movement of the rack.

In a further preferred embodiment, the cooling assembly includes two refrigerators and a plurality of cooling plates disposed in the cooling chamber, so as to cool the liquid nitrogen in the cooling chamber.

In a further preferred embodiment, the cooling chamber is provided with a pump body, and the storage chamber, the pump body and the cooling chamber are connected through a pipeline, so that cooled liquid nitrogen enters the storage chamber.

In a further preferred embodiment, a through hole is formed on one side of the cooling chamber, and the cooling chamber and the storage chamber are communicated through the through hole, so that liquid nitrogen circulation is facilitated.

(III) beneficial effects

Compared with the prior art, the utility model provides a cooling device for cell storage, which has the following beneficial effects:

1. according to the utility model, through the matching of the box body, the storage chamber, the box cover, the opening, the cover body, the limiting ring, the rotary table, the placing hole, the lifting ring, the lifting rod, the placing plate, the driving chamber, the first electric push rod, the pushing plate, the rotary rod, the driving ring, the motor, the driving gear and the driven gear, other test tubes with stem cells can be prevented from being exposed to the outside when a single test tube is taken out, so that the influence on the quality of the stored stem cells is reduced, the quality of the stored stem cells is ensured, meanwhile, the overflow of nitrogen can be reduced, the phenomenon of frostbite of workers is reduced, and the safety of the whole device is improved.

2. According to the utility model, the limit ring, the rotary table, the placement hole, the lifting ring, the lifting rod, the placement disc, the rotary rod, the driven gear, the third electric push rod and the rack are matched, so that the placed stem cell test tube can be cooled and stored, and meanwhile, stem cells in the test tube are uniformly mixed with the frozen stock solution, thereby improving the effect of the frozen protective agent.

3. According to the utility model, the liquid nitrogen can be circularly refrigerated by matching the temperature reducing chamber, the refrigerator, the refrigerating sheet, the pump body and the through hole, so that the temperature reducing effect on stem cells is improved.

Drawings

FIG. 1 is a schematic diagram showing the overall structure of a cooling device for cell storage according to the present utility model;

FIG. 2 is a schematic view showing the whole structure of a cooling device for cell storage according to another aspect of the present utility model;

FIG. 3 is an enlarged schematic view of a portion of FIG. 2A in accordance with the present utility model;

FIG. 4 is a schematic view of a cross-sectional structure of a portion of a case according to the present utility model;

FIG. 5 is a schematic view of a partial cross-sectional structure of a turntable according to the present utility model.

In the figure: 1. a case; 2. a temperature reducing chamber; 3. a storage chamber; 4. a case cover; 5. an opening; 6. a cover body; 7. a limiting ring; 8. a turntable; 9. placing the hole; 10. a lifting ring; 11. a lifting rod; 12. placing a tray; 13. a driving chamber; 14. a first electric push rod; 15. a pushing plate; 16. a rotating rod; 17. a drive ring; 18. a second electric push rod; 19. a motor; 20. a drive gear; 21. a driven gear; 22. a third electric push rod; 23. a rack; 24. a refrigerator; 25. a cooling sheet; 26. a pump body; 27. and a through hole.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

Embodiment one:

referring to fig. 1-5, a cooling device for cell storage includes a box 1, a cooling chamber 2 and a storage chamber 3 are provided in the box 1, a cooling component is provided in the cooling chamber 2, a box cover 4 is provided at the upper end of the storage chamber 3, the box cover 4 is fixedly connected with the box 1 through a plurality of bolts, an opening 5 is provided on the box cover 4, a cover 6 is hinged on the box cover 4, one end of the cover 6 is fixedly connected with the box cover 4 through bolts, a limit ring 7 is provided in the storage chamber 3, a turntable 8 is rotatably connected on the limit ring 7, four placing holes 9 are uniformly provided on the turntable 8, four lifting rings 10 are movably provided on the turntable 8, four lifting rods 11 are symmetrically provided at the lower end of each lifting ring 10, two lifting rods 11 are connected with a placing tray 12 through the turntable 8, a driving chamber 13 is provided in the box 1, a first electric push rod 14 is provided in the driving chamber 13, the driving end of the first electric push rod 14 extends into the storage chamber 3 through the driving chamber 13 and is connected with a pushing plate 15, a rotating component is provided at the lower end of the turntable 8, and the rotating component includes a rotating rod 16 provided at the lower end of the turntable 8.

In this embodiment, the lower end of the box 1 is slidably connected with a driving ring 17 through a track structure, the driving ring 17 is movably sleeved outside the rotating rod 16, the lower end of the box 1 is provided with a second electric push rod 18, the driving end of the second electric push rod 18 is connected with the driving ring 17, the second electric push rod 18 is started, and the second electric push rod 18 drives the driving ring 17 to move along the sliding connection position with the lower end of the box 1.

In this embodiment, a motor 19 is disposed at the lower end of the driving ring 17, a driving gear 20 is disposed at the driving end of the motor 19, a driven gear 21 is connected to the lower end of the rotating rod 16 through the case 1, the driving gear 20 is engaged with the driven gear 21, the motor 19 is started, the motor 19 drives the driving gear 20 to rotate, and the driving gear 20 drives the driven gear 21 to rotate.

In this embodiment, a third electric push rod 22 is disposed at the lower end of the driving ring 17, a rack 23 matched with the driven gear 21 is disposed at the driving end of the third electric push rod 22, the rack 23 is slidably connected with the driving ring 17 through a track structure, the third electric push rod 22 is started, and the third electric push rod 22 drives the rack 23 to move along the sliding connection position with the driving ring 17.

In this embodiment, the cooling component includes two refrigerators 24 and a plurality of refrigerating sheets 25 disposed in the cooling chamber 2, and liquid nitrogen is placed in the cooling chamber 2, and the refrigerating sheets 25 and the refrigerating sheets 24 are started, so that the refrigerating sheets 25 and the refrigerating sheets 24 cool the liquid nitrogen in the cooling chamber 2.

In this embodiment, the pump body 26 is disposed in the cooling chamber 2, the storage chamber 3, the pump body 26 and the cooling chamber 2 are connected through pipes, the pump body 26 is started, and the pump body 26 conveys cooled liquid nitrogen into the storage chamber 3.

In the present embodiment, the cooling chamber 2 is provided with a through hole 27 on one side, the cooling chamber 2 and the storage chamber 3 are provided in communication through the through hole 27, and when the liquid nitrogen in the storage chamber 3 rises to the through hole 27, the liquid nitrogen flows into the cooling chamber 2 from the through hole 27.

Embodiment two:

to sum up, in the use, when the test tube of stem cell is placed in the heat sink and is cooled down and store, rotatory bolt on the lid 6 for bolt and box 1 separation, rotatable lid 6 this moment, make lid 6 around articulated junction rotation with box 1, thereby expose opening 5, put into the test tube from opening 5, the test tube can pass lift ring 10 and place hole 9 and place on placing the dish 12, when a plurality of test tubes need be placed, start motor 19, motor 19 drives driving gear 20 rotation, driving gear 20 drives driven gear 21 rotation, driven gear 21 drives bull stick 16 and carousel 8 rotation, make carousel 8 rotation 90 degrees, can put into bin 3 with the second test tube, so can place four test tubes, after the test tube is placed, close lid 6 and screw up the bolt, fix lid 6 and case lid 4. There is liquid nitrogen in the cooling chamber 2, start refrigerating plate 25 and refrigerator 24 for refrigerating plate 25 and refrigerator 24 cool down the liquid nitrogen in the cooling chamber 2, start pump body 26, pump body 26 carries the liquid nitrogen after cooling to the test tube that has stem cell in the apotheca 3 to cool down, when the liquid nitrogen in the apotheca 3 rises to through-hole 27, the liquid nitrogen can flow into in the cooling chamber 2 from through-hole 27, so carries out the liquid nitrogen circulation and cools down in the apotheca 3.

Embodiment III:

in summary, in the use, when cooling, start second electric putter 18, second electric putter 18 drives drive ring 17 along the department of sliding connection with box 1 lower extreme and removes for drive gear 20 and driven gear 21 separation, rack 23 and driven gear 21 meshing are connected, start third electric putter 22, third electric putter 22 drive rack 23 along the department of sliding connection with drive ring 17 round trip movement, rack 23 drive driven gear 21, bull stick 16, carousel 8 and carousel 8 are last test tube round trip rotation of placing, thereby mix the stem cell in the test tube with the frozen stock evenly.

Embodiment four:

in sum, in the use, when needing to take out single test tube, third electric putter 22 stops the operation, start second electric putter 18, second electric putter 18 drives drive ring 17 along the department of sliding connection with box 1 lower extreme and removes, make rack 23 and driven gear 21 separation, drive gear 20 and driven gear 21 meshing are connected, the starter motor drives carousel 8 and rotates, make the test tube that needs take out rotatory to opening 5 below, motor 19 stops the operation, open lid 6, start first electric putter 14, first electric putter 14 drives push plate 15 upward movement, push plate 15 promotes and places dish 12 upward movement, place dish 12 drives the test tube, lift ring 10 and four lifter 11 upward movement, four lifter 11 are spacing placing dish 12, make the test tube stretch out from opening 5, thereby take out the test tube, start first electric putter 14 after taking out, make placing dish 12, lift ring 10 and four lifter 11 move back normal position, close lid 6, and pass through the bolt fastening can.

In all the above mentioned embodiments, the welding, the matching connection of the bolt and the nut, the bolt or the screw connection or other known connection modes can be selected according to the actual situation, and are not described in detail herein, the above description refers to the write-in fixed connection, and the welding is preferentially considered, but the protection scope of the present utility model is not limited thereto, and any person skilled in the art should be covered by the protection scope of the present utility model if the technical scheme and the inventive concept thereof are equivalent or changed within the scope of the present utility model.

Claims

1. The utility model provides a cell is heat sink for storage, includes box (1), its characterized in that, be equipped with cooling chamber (2) and apotheca (3) in box (1), be equipped with the cooling subassembly in cooling chamber (2), apotheca (3) upper end is equipped with case lid (4), case lid (4) are through a plurality of bolts and box (1) fixed connection, be equipped with opening (5) on case lid (4), articulated on case lid (4) are connected with lid (6), lid (6) one end is through bolt and case lid (4) fixed connection, be equipped with spacing ring (7) in apotheca (3), rotate on spacing ring (7) and be connected with carousel (8), evenly be equipped with four placing hole (9) on carousel (8), the activity is equipped with four lifting ring (10) on carousel (8), every lifting ring (10) lower extreme symmetry is equipped with four lifter (11), two lifter (11) lower extreme are connected with placing disk (12) through carousel (8), be equipped with one electric actuator (13) drive end (13) in the drive chamber (13) and drive end (13), the rotary assembly is arranged at the lower end of the rotary table (8), and comprises a rotary rod (16) arranged at the lower end of the rotary table (8).

2. The cooling device for cell storage of claim 1, wherein: the lower end of the box body (1) is slidably connected with a driving ring (17) through a track structure, the driving ring (17) is movably sleeved outside the rotating rod (16), a second electric push rod (18) is arranged at the lower end of the box body (1), and the driving end of the second electric push rod (18) is connected with the driving ring (17).

3. The cooling device for cell storage according to claim 2, wherein: the lower end of the driving ring (17) is provided with a motor (19), the driving end of the motor (19) is provided with a driving gear (20), the lower end of the rotating rod (16) penetrates through the box body (1) to be connected with a driven gear (21), and the driving gear (20) is meshed with the driven gear (21).

4. A cooling device for cell storage according to claim 3, wherein: the lower end of the driving ring (17) is provided with a third electric push rod (22), the driving end of the third electric push rod (22) is provided with a rack (23) matched with the driven gear (21), and the rack (23) is in sliding connection with the driving ring (17) through a track structure.

5. The cooling device for cell storage of claim 1, wherein: the cooling assembly comprises two refrigerators (24) and a plurality of refrigerating sheets (25) which are arranged in the cooling chamber (2).

6. The cooling device for cell storage of claim 5, wherein: the cooling chamber (2) is internally provided with a pump body (26), and the storage chamber (3), the pump body (26) and the cooling chamber (2) are connected through pipelines.

7. The cooling device for cell storage of claim 6, wherein: one side of the cooling chamber (2) is provided with a through hole (27), and the cooling chamber (2) and the storage chamber (3) are communicated through the through hole (27).