CN219646764U - Solid phase microextraction device for extracting trace substances in extracting solution - Google Patents
Solid phase microextraction device for extracting trace substances in extracting solution Download PDFInfo
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- CN219646764U CN219646764U CN202321179948.9U CN202321179948U CN219646764U CN 219646764 U CN219646764 U CN 219646764U CN 202321179948 U CN202321179948 U CN 202321179948U CN 219646764 U CN219646764 U CN 219646764U
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- extraction
- protection tube
- phase microextraction
- transmission bar
- extract
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- 238000002470 solid-phase micro-extraction Methods 0.000 title claims abstract description 29
- 239000000126 substance Substances 0.000 title claims abstract description 24
- 238000000605 extraction Methods 0.000 claims abstract description 141
- 239000000835 fiber Substances 0.000 claims abstract description 64
- 239000007788 liquid Substances 0.000 claims abstract description 60
- 230000005540 biological transmission Effects 0.000 claims abstract description 35
- 238000007789 sealing Methods 0.000 claims abstract description 7
- 229910000831 Steel Inorganic materials 0.000 claims description 6
- 239000010959 steel Substances 0.000 claims description 6
- 230000009471 action Effects 0.000 claims description 3
- 238000004458 analytical method Methods 0.000 abstract description 7
- 238000001514 detection method Methods 0.000 abstract description 7
- 238000003756 stirring Methods 0.000 abstract description 7
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 241001411320 Eriogonum inflatum Species 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 238000003780 insertion Methods 0.000 description 4
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- 238000010586 diagram Methods 0.000 description 3
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- 238000000926 separation method Methods 0.000 description 3
- 230000007547 defect Effects 0.000 description 2
- 238000003795 desorption Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229920001410 Microfiber Polymers 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
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- 229930014626 natural product Natural products 0.000 description 1
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- 231100000027 toxicology Toxicity 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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- Sampling And Sample Adjustment (AREA)
Abstract
The utility model discloses a solid-phase microextraction device for extracting trace substances in an extraction liquid, which comprises extraction fibers, an extraction liquid bottle containing the extraction liquid, a transmission bar and a protection tube, wherein first ends of two ends of the protection tube are provided with protection tube covers which are connected in a sealing manner, second ends of two ends of the protection tube are provided with openings, the extraction fibers are in a curve shape, the first ends of the two ends of the extraction fibers are connected with the first ends of the two ends of the transmission bar, the extraction fibers are arranged in the protection tube, the second ends of the two ends of the transmission bar penetrate through corresponding through holes on the protection tube covers and are arranged outside the protection tube, and the second ends of the protection tube are arranged in the extraction liquid bottle. The utility model increases the contact length and the surface area of the extraction liquid, increases the trace substances in the extraction liquid obtained by extraction, and is beneficial to the subsequent detection and analysis; the purpose of stirring the extraction liquid can be realized by utilizing the curve-shaped structure of the extraction fibers, and the stirring purpose is realized by no longer shaking the extraction fibers, so that the extraction fibers are better protected from being easily broken.
Description
Technical Field
The utility model belongs to the technical field of solid-phase microextraction, and particularly relates to a solid-phase microextraction device for extracting trace substances in an extract.
Background
Solid Phase Microextraction (SPME) technology was proposed in 1989 by Pawlinszyn, university of Waterloo, canada and its partner Arthur et al, and was originally applied to environmental chemistry analysis (water, soil, atmosphere, etc.), and with the development of research and the continuous perfection of the method itself and improvement of the apparatus, it has now been gradually expanded to various fields of foods, natural products, medical sanitation, clinical chemistry, biochemistry, toxicology, forensics, etc. The solid phase microextraction technology overcomes the defects of the traditional sample pretreatment technology, integrates sampling, extraction and concentration, and greatly accelerates the analysis and detection. The remarkable technical advantages are receiving general attention of analysts in the environmental, food and pharmaceutical industries and greatly promoting the application.
The solid phase micro extraction technology utilizes micro fibers bonded or coated with compounds with different polarities to selectively adsorb trace organic matters in an extraction solution, so that a target object is separated from a sample matrix, and then a proper desorbing agent is selected for desorption, thereby realizing enrichment and separation of the target object, and after the adsorbed matters are desorbed, the adsorbed matters are identified by combining gas chromatography, liquid chromatography and the like.
The solid phase microextraction technology is divided into two processes of extraction and desorption, the basic structure of the solid phase microextraction device comprises extraction fibers bonded or coated with compounds with different polarities, the extraction fibers are generally connected with other handles or clamping mechanisms, the extraction fibers are placed in an extraction liquid bottle containing extraction liquid during operation, and the extraction liquid is stirred by shaking the extraction fibers, so that trace substances in the extraction liquid are more fully combined with the compounds on the extraction fibers, and the extraction fibers are taken out after a certain time, thus the operation of the extraction process is completed.
The traditional solid phase microextraction device has the following defects: the extraction fiber is in a straight line shape, the contact length and the surface area of the extraction fiber and the extraction liquid are small, trace substances in the extraction liquid obtained by extraction are less, the extraction efficiency is low, and the subsequent detection and analysis are not facilitated; during the stirring process by the extraction fiber, the extremely fine extraction limit may break; in addition, because the stirring requires an operation space, the upper end bottle mouth of the extraction liquid bottle cannot be closed, and if volatile substances to be detected such as formaldehyde exist in the extraction liquid, the volatile substances can leak out through the upper end bottle mouth of the extraction liquid bottle, so that trace substances obtained by extraction are further reduced.
Disclosure of Invention
The utility model aims to solve the problems and provide a solid-phase microextraction device for extracting trace substances in an extraction liquid, which has the advantages of increasing extraction efficiency, avoiding breakage of extraction fibers and avoiding volatilization of substances in the extraction liquid.
The utility model realizes the above purpose through the following technical scheme:
the utility model provides a solid-phase microextraction device for extraction of trace material in extract, includes extraction fibre and holds the extract bottle of extract, still includes drive bar and protection tube, the first end in the protection tube both ends is equipped with sealing connection's protection tube cap, the second end opening in the protection tube both ends, extraction fibre is curve shape and the first end in its both ends with the first end in the drive bar both ends is connected, extraction fibre is arranged in the protection tube, the second end in the drive bar both ends passes corresponding through-hole on the protection tube cap and arrange in outside the protection tube, the second end of protection tube is arranged in the extract bottle.
Preferably, in order to enable the protection tube and the extraction liquid bottle to have a better sealing effect and facilitate extraction operation, an extraction liquid bottle stopper made of rubber is arranged at the bottle opening of the extraction liquid bottle, the second end of the protection tube is a tip, and the tip penetrates through the extraction liquid bottle stopper and is arranged in the extraction liquid bottle.
Preferably, in order to facilitate the insertion and separation operation between the protection tube and the extraction liquid bottle, the solid-phase microextraction device for extracting trace substances in the extraction liquid further comprises an outer barrel, wherein first ends of two ends of the outer barrel are provided with outer barrel covers, second ends of two ends of the outer barrel are provided with outer barrel plugs, the middle section of the protection tube is arranged in the outer barrel, and the protection tube penetrates through the outer barrel covers and the outer barrel plugs.
Preferably, in order to facilitate operation and realize a good limiting function, the protection tube cover and the outer cylinder cover are both rubber covers, and the outer cylinder plug is a rubber plug.
Preferably, in order to better limit the transmission bar and the extraction fiber so as to reduce the shaking of the transmission bar and the extraction fiber and better protect the extraction fiber, a transmission bar limit bracket is arranged on the transmission bar at a position close to the first end of the transmission bar, an extraction fiber limit bracket is arranged on the extraction fiber at a position close to the second end of the extraction fiber, and a plurality of outer ends of the transmission bar limit bracket and a plurality of outer ends of the extraction fiber limit bracket are respectively contacted with the inner wall of the protection tube.
Preferably, in order to facilitate the insertion and rotation operation of the transmission bar, the second end of the transmission bar is connected with an operation handle.
Preferably, in order to facilitate smooth transmission, the transmission bar is a steel wire, and the steel wire can slide smoothly in the axial direction of the protection tube under the action of external force.
Preferably, the extraction fibers have a spiral shape in order to increase the surface area of the length of the extraction fibers as much as possible at the same height.
The utility model has the beneficial effects that:
according to the utility model, the shape of the extracted fiber is designed into a curve shape, so that the contact length and the surface area of the extracted fiber with the extraction liquid are increased on the premise of being inserted into the extraction liquid bottle to the same depth, trace substances in the extraction liquid obtained by extraction are increased, and the subsequent detection and analysis are facilitated; the extraction fiber is driven to rotate by the transmission strip, the purpose of stirring the extraction liquid can be realized by utilizing the curve-shaped structure of the extraction fiber, and the stirring purpose is not realized by shaking the extraction fiber, so that the extraction fiber is better protected from being easily broken; through increasing the protection pipe and designing its open end as the pointed end to adopt the extract bottle plug of rubber preparation, the pointed end of protection pipe can easily insert in the extract bottle and keep sealing state, thereby avoid the volatile material in the extract to volatilize from the bottleneck of extract bottle.
Drawings
FIG. 1 is a schematic diagram showing the front view of the solid phase microextraction device for extracting trace substances from an extract, with an extract bottle removed;
FIG. 2 is a schematic diagram showing the front view of the solid phase microextraction device for extracting trace substances from an extract liquid according to the present utility model;
FIG. 3 is a schematic diagram showing the front view of the solid phase microextraction device for extracting trace substances from an extract liquid according to the present utility model.
Description of the embodiments
The utility model is further described below with reference to the accompanying drawings:
as shown in fig. 1, 2 and 3, the solid-phase microextraction device for extracting trace substances in an extraction liquid according to the present utility model comprises an extraction fiber 7, an extraction liquid bottle 13 containing the extraction liquid 14, a transmission bar 2 and a protection tube 4, wherein a protection tube cover 3 is provided at a first end (an upper end in the drawing) of two ends of the protection tube 4 in a sealing connection, a second end (a lower end in the drawing) of the two ends of the protection tube 4 is opened, the extraction fiber 7 is in a curve shape, the first end (the upper end in the drawing) of the two ends of the extraction fiber 7 is connected with the first end (the lower end in the drawing) of the two ends of the transmission bar 2, the extraction fiber 7 is placed in the protection tube 4, the second end (the upper end in the drawing) of the two ends of the transmission bar 2 passes through corresponding through holes on the protection tube cover 3 and is placed outside the protection tube 4, and the second end of the protection tube 4 is placed in the extraction liquid bottle 13.
As shown in fig. 1, 2 and 3, the present utility model also discloses the following various more optimal specific structures:
in order to make the protection tube 4 and the extraction liquid bottle 13 have better sealing effect and facilitate the extraction operation, the bottle mouth of the extraction liquid bottle 13 is provided with an extraction liquid bottle stopper 12 made of rubber, the second end of the protection tube 4 is a tip 11, and the tip 11 penetrates through the extraction liquid bottle stopper 12 and is arranged in the extraction liquid bottle 13.
In order to facilitate the insertion and separation operation between the protection tube 4 and the extraction liquid bottle 13, the solid-phase microextraction device for extracting trace substances in the extraction liquid further comprises an outer tube 8, wherein the outer tube 8 is provided with an outer tube cover 5 at a first end (an upper end in the figure) of two ends of the outer tube 8, an outer tube plug 10 is provided at a second end (a lower end in the figure) of two ends of the outer tube 8, the middle section of the protection tube 4 is arranged in the outer tube 8, and the protection tube 4 penetrates through the outer tube cover 5 and the outer tube plug 10.
In order to facilitate operation and realize a good limiting function, the protection tube cover 3 and the outer cylinder cover 5 are both rubber covers, and the outer cylinder plug 10 is a rubber plug.
In order to better limit the transmission bar 2 and the extraction fibers 7 so as to reduce shaking and better protect the extraction fibers 7, a transmission bar limit bracket 6 is arranged on the transmission bar 2 near the first end of the transmission bar, an extraction fiber limit bracket 9 is arranged on the extraction fibers 7 near the second end of the extraction fibers, and a plurality of outer ends of the transmission bar limit bracket 6 and a plurality of outer ends of the extraction fiber limit bracket 9 are respectively contacted with the inner wall of the protection tube 4.
In order to facilitate the insertion and rotation operation of the transmission bar 2, the second end of the transmission bar 2 is connected with an operation handle 1.
In order to facilitate smooth transmission, the transmission bar 2 is a steel wire, and the steel wire can slide smoothly in the axial direction of the protection tube 4 under the action of external force.
In order to increase the surface area of the length of the extraction fibers 7 as much as possible at the same height, the extraction fibers 7 have a spiral shape.
As shown in fig. 2 and 3, when in use, firstly, the extraction liquid 14 is filled into the extraction liquid bottle 13, the extraction liquid bottle stopper 12 is covered on the bottle mouth of the extraction liquid bottle 13, then the tip 11 of the assembled protection tube 4 is inserted into the extraction liquid bottle stopper 12 and is positioned above the extraction liquid 14 in the extraction liquid bottle 13, the operation handle 1 is held by hand to push downwards in the figure, the operation handle 1 is stopped to push downwards until the vast majority of the extraction fibers 7 are placed in the extraction liquid 14, the operation handle 1 is held to rotate, the spiral structure of the extraction fibers 7 is used for realizing the stirring function of the extraction liquid 14, the extraction fibers 7 do not need to shake, the pressure of the extraction liquid 14 on the extraction fibers 7 is reduced, and the extraction fibers 7 are better protected from breaking. After a certain time, the trace substances in the extraction liquid 14 are fully combined with the solid-phase substances on the extraction fibers 7, and then the operation handle 1 is held by hands to pull upwards in the figure until the extraction fibers 7 are completely placed in the protection tube 4, thus completing the operation of the extraction flow. Then, the extracted fiber 7 may be placed in an analytical solution for analysis, and then the analytical solution may be subjected to component detection and analysis by a gas chromatograph or a gas chromatograph. The operation can be used in the fields of medicine, chemistry, biology and the like, such as detection of aldehydes in urine, detection of volatile organic substances in water and the like.
The above embodiments are only preferred embodiments of the present utility model, and are not limiting to the technical solutions of the present utility model, and any technical solution that can be implemented on the basis of the above embodiments without inventive effort should be considered as falling within the scope of protection of the patent claims of the present utility model.
Claims (8)
1. A solid phase microextraction device for extracting trace substances in extract, includes extraction fiber and holds extract bottle that holds extract, its characterized in that: the extraction device comprises a liquid extraction bottle, and is characterized by further comprising a transmission bar and a protection tube, wherein first ends of the two ends of the protection tube are provided with protection tube covers in sealing connection, second ends of the two ends of the protection tube are provided with openings, the extraction fibers are in a curve shape, the first ends of the two ends of the extraction fibers are connected with the first ends of the two ends of the transmission bar, the extraction fibers are arranged in the protection tube, second ends of the two ends of the transmission bar penetrate through corresponding through holes in the protection tube covers and are arranged outside the protection tube, and the second ends of the protection tube are arranged in the extraction liquid bottle.
2. The solid phase microextraction device for extraction of trace species from an extract as claimed in claim 1, wherein: the bottle mouth of the extraction liquid bottle is provided with an extraction liquid bottle plug made of rubber, the second end of the protection tube is a tip, and the tip penetrates through the extraction liquid bottle plug and is arranged in the extraction liquid bottle.
3. The solid phase microextraction device for extraction of trace species from an extract as claimed in claim 2, wherein: the solid-phase microextraction device for extracting trace substances in the extract liquid further comprises an outer barrel, wherein first ends of two ends of the outer barrel are provided with outer barrel covers, second ends of two ends of the outer barrel are provided with outer barrel plugs, the middle section of the protection pipe is arranged in the outer barrel, and the protection pipe penetrates through the outer barrel covers and the outer barrel plugs.
4. A solid phase microextraction device for extraction of trace species from an extract as claimed in claim 3 wherein: the protection tube cover and the outer cylinder cover are both rubber covers, and the outer cylinder plug is a rubber plug.
5. The solid phase microextraction device for extraction of trace species from an extract according to any one of claims 1 to 4, wherein: the position on the transmission bar near the first end of the transmission bar is provided with a transmission bar limiting support, the position on the extraction fiber near the second end of the extraction fiber is provided with an extraction fiber limiting support, and a plurality of outer ends of the transmission bar limiting support and a plurality of outer ends of the extraction fiber limiting support are respectively contacted with the inner wall of the protection tube.
6. The solid phase microextraction device for extraction of trace species from an extract according to any one of claims 1 to 4, wherein: the second end of the transmission bar is connected with an operating handle.
7. The solid phase microextraction device for extraction of trace species from an extract according to any one of claims 1 to 4, wherein: the transmission strip is a steel wire, and the steel wire can smoothly slide in the axial direction of the protection tube under the action of external force.
8. The solid phase microextraction device for extraction of trace species from an extract according to any one of claims 1 to 4, wherein: the extraction fiber is in a spiral shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321179948.9U CN219646764U (en) | 2023-05-16 | 2023-05-16 | Solid phase microextraction device for extracting trace substances in extracting solution |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321179948.9U CN219646764U (en) | 2023-05-16 | 2023-05-16 | Solid phase microextraction device for extracting trace substances in extracting solution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219646764U true CN219646764U (en) | 2023-09-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321179948.9U Active CN219646764U (en) | 2023-05-16 | 2023-05-16 | Solid phase microextraction device for extracting trace substances in extracting solution |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219646764U (en) |
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2023
- 2023-05-16 CN CN202321179948.9U patent/CN219646764U/en active Active
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