CN219642259U - Reagent reaction equipment and kit - Google Patents

Reagent reaction equipment and kit Download PDF

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Publication number
CN219642259U
CN219642259U CN202223526516.9U CN202223526516U CN219642259U CN 219642259 U CN219642259 U CN 219642259U CN 202223526516 U CN202223526516 U CN 202223526516U CN 219642259 U CN219642259 U CN 219642259U
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reagent
kit
information
chip
radio frequency
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CN202223526516.9U
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张彤
孟佳
邵京
王远
贾海舟
王国伟
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Zhengzhou Sikun Biological Engineering Co ltd
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Zhengzhou Sikun Biological Engineering Co ltd
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Abstract

The present disclosure provides a reagent reaction apparatus and a kit, the reagent reaction apparatus comprising: the device comprises a processor, a radio frequency card reader and a containing component, wherein the containing component is used for containing the reagent kit; the kit is provided with a radio frequency chip which is used for storing chip information corresponding to the radio frequency chip; the radio frequency card reader is used for reading the chip information of the radio frequency chip on the kit; and the processor is used for judging whether the kit is suitable for the reagent reaction equipment based on the chip information read by the radio frequency card reader, and if so, carrying out a reaction based on the reagent stored in the kit to obtain a reagent reaction result. According to the embodiment of the disclosure, more information can be recorded by utilizing the radio frequency chip, meanwhile, the radio frequency chip is arranged on the kit, and the chip information of the radio frequency chip on the kit is read through the radio frequency card reader, so that whether the kit is suitable for the reagent reaction equipment or not can be automatically judged, the reagent used in the reagent reaction process is ensured to be a correct reagent, and the correctness of the reagent reaction is ensured.

Description

Reagent reaction equipment and kit
Technical Field
The disclosure relates to the technical field of gene sequencing, in particular to reagent reaction equipment and a reagent kit.
Background
In the technical field of gene sequencing, a barcode or a two-dimensional code is generally used to record information about a reagent when a reagent reaction is performed; however, the information capacity recorded by the information recording mode is low, and the bar code or the two-dimensional code is easy to damage or pollute, so that the recorded information is lost or cannot be identified; meanwhile, when the mode is used for recording information, the gun head identification information is required to be scanned through manual operation, the consumed time cost and labor cost are high, the information identification efficiency is low, and further the reaction process of the reagent is possibly wrong, and the accuracy of the reagent reaction cannot be guaranteed.
Disclosure of Invention
In view of this, the disclosure provides a reagent reaction device and a kit at least, and the reagent reaction device and the kit are used for identifying whether to match through a radio frequency card reader, so as to ensure the accuracy of the reagent reaction.
In a first aspect, the present disclosure provides a reagent reaction apparatus comprising: the device comprises a processor, a radio frequency card reader and a containing component, wherein the containing component is used for containing the kit; the kit is provided with a radio frequency chip which is used for storing chip information corresponding to the radio frequency chip;
the radio frequency card reader is used for reading the chip information of the radio frequency chip on the kit;
and the processor is used for judging whether the kit is suitable for the reagent reaction equipment or not based on the chip information read by the radio frequency card reader, and if so, carrying out a reaction based on the reagent stored in the kit to obtain a reagent reaction result.
Here, by mounting a radio frequency chip on a kit, chip information indicating the type of the kit can be stored using the radio frequency chip; after the reagent kit is placed in the accommodating part of the reagent reaction equipment, the radio frequency card reader included in the reagent reaction equipment can be used for reading the chip information of the radio frequency chip on the reagent kit, and then the processor can judge whether the reagent kit is matched with the reagent reaction equipment or not based on the read chip information, if so, the reagent kit reacts based on the reagent stored in the reagent kit, and a reagent reaction result is obtained, so that the correctness of the used reagent is ensured, and the normal performance of the reagent reaction is ensured.
Meanwhile, the information capacity which can be stored by utilizing the radio frequency chip is larger, and the radio frequency chip is arranged on the kit, so that the kit is not easy to damage and pollute, and the stored information is safer; and the reagent reaction device is utilized to carry out reagent reaction, so that the need of manually judging whether the used reagent is correct or not is eliminated, the consumption of labor cost and time cost is reduced, and the efficiency of the reagent reaction is improved.
In a possible embodiment, the processor is further configured to: and generating first alarm information when the reagent kit is not matched with the reagent reaction equipment.
Here, when confirming that kit and reagent reaction equipment are not fit, generate first warning information, the reagent that reminds the staff that can be timely is wrong reagent to ensure that the reagent reaction can normally go on, and, the kit that the staff of being convenient for can in time confirm to appear the problem reduces the loss, has improved the security and the reaction efficiency of equipment.
In a possible implementation manner, in a case that the accommodating part accommodates a plurality of types of kits, the radio frequency card reader is further used for respectively reading chip information of the radio frequency chip on each of the plurality of types of kits;
the processor is further configured to determine whether the multiple types of kits are matched based on chip information of the radio frequency chip on each kit, and if the multiple types of kits are not matched, generate second alarm information.
Here, in the case where the accommodating part accommodates a plurality of types of kits, chip information of the radio frequency chip on each of the plurality of types of kits is read by using the radio frequency card reader, respectively; further, the processor judges whether the multiple types of reagent kits are matched based on the chip information of the radio frequency chip on each reagent kit, if not, second alarm information is generated, the reagent reaction can be normally carried out, and the reagent reaction efficiency is improved.
In a possible implementation manner, the processor is configured to, when determining whether the multiple types of kits match based on the chip information of the radio frequency chip on each of the kits:
and judging whether the plurality of kits are matched or not based on the chip flux information and/or the chip model information in the chip information.
In order to avoid the problem of reaction failure caused by reagent waste or insufficient amount of used reagent, before reagent reaction is carried out, judging whether a plurality of reagent boxes are matched or not based on chip flux information in chip information; and in order to ensure that the used reagents can react according to the requirements, before the reagent reaction is carried out, judging whether the various reagent boxes are matched or not based on the chip type information in the chip information so as to improve the accuracy of the reagent reaction.
In a possible embodiment, the radio frequency chip on the kit is further used for storing reagent information of reagents in the kit;
the radio frequency card reader is also used for reading the reagent information stored by the radio frequency chip on the kit;
the processor is further used for judging whether the reagent stored in the kit is in a valid state or not based on the reagent production time and the valid period contained in the reagent information; and if the alarm signal is not in the effective state, generating third alarm information.
Here, the processor can judge whether the reagent is in an effective state based on the reagent information stored by the radio frequency chip on the reagent kit read by the radio frequency card reader, so that the effectiveness of the reagent is ensured, and the accuracy of the reagent reaction result is improved.
In a possible embodiment, the processor is further configured to determine, based on the identification information included in the reagent information, whether the reagent stored in the kit has been used; if yes, fourth alarm information is generated.
In consideration of the fact that the used reagent is polluted, the processor judges whether the reagent stored in the kit is used or not, if yes, fourth warning information is generated, accuracy of a reagent reaction result can be guaranteed, and reagent reaction efficiency is improved.
In a possible embodiment, the reagent reaction device further comprises: a syringe pump;
the injection pump is used for injecting the reagent into the kit body of the kit or extracting the reagent from the kit body.
Here, by installing the syringe pump on the reagent reaction apparatus, the reagent can be conveniently extracted from the reagent box body of the reagent box, or the reagent can be injected into the reagent box body of the reagent box, thereby improving the working efficiency of the reagent reaction apparatus.
In a possible embodiment, the reagent reaction device further comprises: a catheter detachably connected to the syringe pump;
the catheter is used for conveying the reagent pumped by the injection pump.
Here, the catheter is detachably connected with the injection pump, and the catheter can be used for conveying the reagent pumped by the injection pump so that the reagent reaction can be carried out later and the normal operation of the reagent reaction is ensured.
In a possible embodiment, the reagent reaction device further comprises: a display coupled to the processor;
the processor is used for controlling the display to display the alarm information after the alarm information is generated, wherein the alarm information comprises at least one of first alarm information, second alarm information, third alarm information and fourth alarm information.
Here, through linking to each other the display with the treater, can control the display to demonstrate alarm information after the treater generates alarm information to can in time point out the staff when abnormal conditions appears, ensure that reagent reaction can normally go on, can improve reagent reaction result's accuracy.
In a possible embodiment, the reagent reaction device further comprises: a voice player connected with the processor and/or an alarm lamp connected with the processor;
the processor is used for controlling the voice player to play the alarm information after the alarm information is generated and/or controlling the alarm lamp to flash.
Here, through linking to each other voice player and/or warning light with the treater, can be after the treater generates alarm information, control voice player broadcast alarm information and/or, control warning light glimmers to can in time indicate the staff when abnormal conditions appears, guarantee reagent reaction can normally go on, can improve reagent reaction result's accuracy.
In a second aspect, the present disclosure provides a kit comprising: a radio frequency chip;
the radio frequency chip is used for storing chip information so that a radio frequency card reader on the reagent reaction device can read the chip information, and a processor on the reagent reaction device can judge whether the reagent kit is suitable for the reagent reaction device or not based on the read chip information.
Here, through installing the radio frequency chip on the kit, utilize the radio frequency chip to store the chip information, the information capacity stored is great, and install the radio frequency chip on the kit, not fragile and pollute, in order to guarantee the validity of the information; meanwhile, the radio frequency chip is arranged on the reagent kit, chip information is automatically read through the radio frequency card reader, the read chip information is identified through the processor, whether the reagent kit is suitable for the reagent reaction equipment or not is not required to be judged manually, and the working efficiency of the reagent reaction equipment is improved.
In a possible embodiment, the kit further comprises: a kit body and a kit upper cover; the upper cover of the kit is placed on the kit body; the kit body is used for storing the reagent.
Here, the kit body that the kit includes can deposit reagent, and the kit upper cover can be placed on the kit body, and protection reagent that can be better is not polluted for the accuracy of the reagent reaction result that obtains is higher.
The foregoing objects, features and advantages of the disclosure will be more readily apparent from the following detailed description of the preferred embodiments taken in conjunction with the accompanying drawings.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present disclosure, the drawings required for the embodiments are briefly described below, which are incorporated in and constitute a part of the specification, these drawings showing embodiments consistent with the present disclosure and together with the description serve to illustrate the technical solutions of the present disclosure. It is to be understood that the following drawings illustrate only certain embodiments of the present disclosure and are therefore not to be considered limiting of its scope, for the person of ordinary skill in the art may admit to other equally relevant drawings without inventive effort.
Fig. 1 shows a schematic structural diagram of a reagent reaction apparatus and a reagent kit according to an embodiment of the present disclosure;
FIG. 2a shows a schematic structural diagram of a kit provided by an embodiment of the present disclosure;
FIG. 2b shows a schematic structural diagram of another kit provided by embodiments of the present disclosure;
FIG. 3 is a schematic view showing the structure of a syringe pump and a catheter in a reagent reaction apparatus according to an embodiment of the present disclosure;
FIG. 4 is a schematic diagram showing a structure of a reagent reaction apparatus according to an embodiment of the present disclosure, including a display connected to a radio frequency card reader;
FIG. 5 is a schematic diagram showing a configuration of a reagent reaction apparatus according to an embodiment of the present disclosure, including a voice player connected to a radio frequency card reader;
fig. 6 shows a schematic structural diagram of a kit body and a kit upper cover in a kit provided in an embodiment of the disclosure;
FIG. 7 is a schematic diagram showing the structure of an upper cover of another kit in the kit according to the embodiment of the disclosure;
fig. 8 is a schematic structural view of a chip gripper in a reagent reaction apparatus according to an embodiment of the present disclosure.
Detailed Description
For the purposes of making the objects, technical solutions and advantages of the embodiments of the present disclosure more apparent, the technical solutions of the embodiments of the present disclosure will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present disclosure, and it is apparent that the described embodiments are only some embodiments of the present disclosure, not all embodiments. The components of the embodiments of the present disclosure, which are generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the present disclosure provided in the accompanying drawings is not intended to limit the scope of the disclosure, as claimed, but is merely representative of selected embodiments of the disclosure. All other embodiments, which can be made by those skilled in the art based on the embodiments of this disclosure without making any inventive effort, are intended to be within the scope of this disclosure.
In the technical field of gene sequencing, a barcode or a two-dimensional code is generally used to record information about a reagent when a reagent reaction is performed; however, the information capacity recorded by the information recording mode is low, and the bar code or the two-dimensional code is easy to damage or pollute, so that the recorded information is lost or cannot be identified; meanwhile, when the mode is used for recording information, the gun head identification information is required to be scanned through manual operation, the consumed time cost and labor cost are high, the information identification efficiency is low, and further the reaction process of the reagent is possibly wrong, and the accuracy of the reagent reaction cannot be guaranteed.
In order to alleviate the above problems, embodiments of the present disclosure provide a reagent reaction apparatus and a kit.
The above solution has the drawbacks that the applicant has obtained after practice and careful study, and therefore the discovery process of the above problems and the solutions to the problems that the present disclosure hereinafter proposes should be all contributions to the present disclosure by the applicant during the process of the present disclosure.
It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.
For ease of understanding the embodiments of the present disclosure, a calibration plate support disclosed in the embodiments of the present disclosure will be described in detail first.
Referring to fig. 1, a schematic diagram of a reagent reaction apparatus according to an embodiment of the present disclosure includes: the processor, the radio frequency reader 11 and the receiving means 12 are not shown in fig. 1, since the processor is not visible inside the reagent reaction device; the accommodating member 12 is for accommodating a reagent cartridge 13; the kit 13 is provided with a radio frequency chip 14, and the radio frequency chip 14 is used for storing chip information corresponding to the radio frequency chip.
The radio frequency card reader 11 is used for reading the chip information of the radio frequency chip 14 on the kit 13.
And the processor is used for judging whether the kit 13 is suitable for the reagent reaction equipment based on the chip information, and if so, carrying out a reaction based on the reagent stored in the kit 13 to obtain a reagent reaction result.
In practice, the reagent reaction device may comprise a processor, a radio frequency reader and a receiving member, which may be used to receive a reagent cartridge; meanwhile, a radio frequency chip is arranged on the kit and can be used for storing chip information corresponding to the radio frequency chip, and the chip information can represent the type of the kit; furthermore, the processor can judge whether the kit is suitable for the reagent reaction device based on the chip information read by the radio frequency card reader, and if so, the reagent reaction can be performed based on the reagent stored in the kit to obtain a reagent reaction result.
For example, if the reagent reaction device is used for reacting the reagent in the reagent kit a with the reagent kit B, after the reagent kit is placed in the accommodating component included in the reagent reaction device, if the radio frequency card reader reads that the chip information of the radio frequency chip on the reagent kit is a-01 and B-01, and the prefix part of the chip information indicates the type of the reagent kit, the type of the reagent kit placed in the reagent reaction device is a reagent kit a and a reagent kit B, that is, the processor can determine that the reagent kit is adapted to the reagent reaction device based on the chip information read by the radio frequency card reader, and can react the reagent in the reagent kit a with the reagent in the reagent kit B, so as to obtain a reagent reaction result.
If the chip information of the radio frequency chip on the kit read by the radio frequency card reader is A-01 and C-01, the type of the kit placed into the reagent reaction device is kit A and kit C, namely the processor can determine that the kit is not suitable for the reagent reaction device based on the chip information read by the radio frequency card reader.
Or, in the case where it is necessary to place the cartridges in the order in the accommodating part of the reagent reaction apparatus, if the cartridges are the cartridge a, the cartridge B, the cartridge C; after the reagent kit A is placed in the accommodating part of the reagent reaction device, the reagent kit B needs to be placed in the accommodating part of the reagent reaction device, if the chip information read by the radio frequency card reader is B-01, the type of the reagent kit placed in the reagent reaction device is the reagent kit B, that is, the processor can determine that the reagent kit is suitable for the reagent reaction device based on the chip information read by the radio frequency card reader. If the chip information read by the radio frequency card reader is C-01, the type of the reagent kit placed into the reagent reaction device is reagent kit C, namely the processor can determine that the reagent kit is not suitable for the reagent reaction device based on the chip information read by the radio frequency card reader.
In the specific implementation, whether the kit is suitable for the reagent reaction equipment can be judged by the upper computer based on the chip information read by the radio frequency card reader; here, the upper computer may include a personal computer (Personal Computer, PC), a host computer, or the like.
Here, by mounting a radio frequency chip on a kit, chip information indicating the type of the kit can be stored using the radio frequency chip; after the reagent kit is placed in the accommodating part of the reagent reaction equipment, the radio frequency card reader included in the reagent reaction equipment can be used for reading the chip information of the radio frequency chip on the reagent kit, and then the processor can judge whether the reagent kit is matched with the reagent reaction equipment or not based on the read chip information, if so, the reagent kit reacts based on the reagent stored in the reagent kit, and a reagent reaction result is obtained, so that the correctness of the used reagent is ensured, and the normal performance of the reagent reaction is ensured.
Meanwhile, the information capacity which can be stored by utilizing the radio frequency chip is larger, and the radio frequency chip is arranged on the kit, so that the kit is not easy to damage and pollute, and the stored information is safer; and the reagent reaction device is utilized to carry out reagent reaction, so that the need of manually judging whether the used reagent is correct or not is eliminated, the consumption of labor cost and time cost is reduced, and the efficiency of the reagent reaction is improved.
In a possible implementation, the processor is further configured to: upon determining that the reagent kit 13 is not compatible with the reagent reaction device, a first warning message is generated.
When the method is implemented, if the processor judges that the kit is not matched with the reagent reaction equipment based on the read chip information, the first alarm information can be generated.
For example, if the reagent reaction device is configured to perform a reagent reaction on a reagent in the reagent kit a, the chip information read by the radio frequency card reader is B-01, that is, indicates that the type of the reagent kit indicated by the chip information is the reagent kit B, the processor may determine that the reagent kit is not matched with the reagent reaction device based on the chip information read by the radio frequency card reader, and generate first alarm information; for example, the first alarm information may be: "kit does not match with the device", or "kit B does not match with the device", etc.
Or, in the case where it is necessary to place the cartridges in the order in the accommodating part of the reagent reaction apparatus, if the cartridges are the cartridge a, the cartridge B, the cartridge C; after the reagent kit A is placed in the accommodating part of the reagent reaction device, the reagent kit B needs to be placed in the accommodating part of the reagent reaction device, and if the chip information read by the radio frequency card reader is C-01, namely the chip information indicates that the type of the reagent kit is the reagent kit C, the processor can determine that the reagent kit is not matched with the reagent reaction device based on the chip information read by the radio frequency card reader, and generate first alarm information.
Here, when confirming that kit and reagent reaction equipment are not fit, generate first warning information, the reagent that reminds the staff that can be timely is wrong reagent to ensure that the reagent reaction can normally go on, and, the kit that the staff of being convenient for can in time confirm to appear the problem reduces the loss, has improved the security and the reaction efficiency of equipment.
In a possible implementation manner, in the case that the accommodating part 12 accommodates a plurality of types of kits 13, the radio frequency card reader 11 is further configured to read chip information of a radio frequency chip on each of the plurality of types of kits;
and the processor is also used for judging whether the multiple types of kits are matched based on the chip information of the radio frequency chip on each kit, and if the multiple types of kits are not matched, generating second alarm information.
Here, in the case where the accommodating part accommodates a plurality of types of kits, chip information of the radio frequency chip on each of the plurality of types of kits is read by using the radio frequency card reader, respectively; further, the processor judges whether the multiple types of reagent kits are matched based on the chip information of the radio frequency chip on each reagent kit, if not, second alarm information is generated, the reagent reaction can be normally carried out, and the reagent reaction efficiency is improved.
In practice, in the case where the accommodating member accommodates a plurality of types of kits, for example, the kit may include a kit a storing a reagent a, a kit B storing a reagent B, and a kit C storing a reagent C. The kit for storing different reagents may be different, see kit a in fig. 2a and kit B in fig. 2B.
In order to ensure that the reagent A, the reagent B and the reagent C are correct reagents required by the experiment, the radio frequency card reader can also be used for respectively reading chip information of radio frequency chips on each of the multiple types of reagent boxes; furthermore, the processor can judge whether the multiple types of kits are matched or not based on the chip information of the radio frequency chip on each kit; if the chip information of the radio frequency chips corresponding to the kit A, the kit B and the kit C are inconsistent, second alarm information can be generated; for example, the second alarm information may be: "mismatch between kits", or "kit C has errors", etc. If the chip information of the radio frequency chips corresponding to the kit A, the kit B and the kit C are consistent, the following steps can be continued.
In a possible embodiment, the processor is configured to, when determining whether a plurality of types of kits match based on chip information of the radio frequency chip on each of the kits: and judging whether the plurality of kits are matched or not based on the chip flux information and/or the chip model information in the chip information.
In the specific implementation, the large amount of the reagent which can be detected by the high-flux chip and the small amount of the reagent which can be detected by the low-flux chip are considered, so that in order to avoid the waste of the reagent or relieve the reduction of the accuracy of the reagent reaction caused by the insufficient amount of the reagent of the used reagent, when judging whether the plurality of types of the reagent boxes are matched or not based on the chip information of the radio frequency chip on each reagent box, the processor can judge whether the plurality of types of the reagent boxes are matched or not based on the chip flux information in the chip information; judging whether the chip flux information is consistent or not; and/or, in order to ensure that the used reagents can react according to the requirements, whether the various kits are matched or not can be judged based on the chip model information in the chip information; i.e. whether the chip model information is the same.
For example, in the case that the kit includes a kit a, a kit B, and a kit C, if the radio frequency card reader can read that the chip information of the radio frequency chip on the kit a is a-01, the chip information of the radio frequency chip on the kit B is B-01, and the chip information of the radio frequency chip on the kit C is C-01; if the suffix part in the chip information indicates the chip model information, and the suffix parts in the chip information A-01, B-01 and C-01 are all 01, the suffix parts indicate that the chip model information among the kit A, the kit B and the kit C is the same, that is, the processor can determine the matching among the kit A, the kit B and the kit C based on the chip model information in the chip information.
If the chip information read by the radio frequency card reader is A-01, B-01 and C-02, the suffix part of the chip information of the radio frequency chip on the kit A and the chip information of the radio frequency chip on the kit B is 01, and the suffix part of the chip information of the radio frequency chip on the kit C is 02, the chip type information of the kit A, the kit B and the kit C is different, that is, the processor can determine that the kit A, the kit B and the kit C are not matched based on the chip type information in the chip information.
Or, the chip flux information in the chip information of the radio frequency chip on the kit can be read; if the radio frequency card reader reads that the chip information of the radio frequency chip on the kit A is 2-3 megabytes, the chip information of the radio frequency chip on the kit B is 2-3 megabytes, and the chip information of the radio frequency chip on the kit C is 2-3 megabytes; it indicates that the chip flux information is consistent between the kit a, the kit B, and the kit C, i.e., the processor may determine a match between the kit a, the kit B, and the kit C based on the chip flux information in the chip information. If the radio frequency card reader reads that the chip information of the radio frequency chip on the kit A is 2-3 megabytes, the chip information of the radio frequency chip on the kit B is 2-3 megabytes, and the chip information of the radio frequency chip on the kit C is 4-6 megabytes; it indicates that the chip flux information is inconsistent between the kit a, the kit B, and the kit C, i.e., the processor may determine a mismatch between the kit a, the kit B, and the kit C based on the chip model information in the chip information.
In order to avoid the problem of reaction failure caused by reagent waste or insufficient amount of used reagent, before reagent reaction is carried out, judging whether a plurality of reagent boxes are matched or not based on chip flux information in chip information; and in order to ensure that the used reagents can react according to the requirements, before the reagent reaction is carried out, judging whether the various reagent boxes are matched or not based on the chip type information in the chip information so as to improve the accuracy of the reagent reaction.
In a possible embodiment, the radio frequency chip 14 on the kit 13 is also used to store reagent information of the reagents in the kit.
The radio frequency card reader 11 is also used for reading the reagent information stored by the radio frequency chip on the reagent kit.
The processor is also used for judging whether the reagent stored in the kit is in a valid state or not based on the production time and the valid period of the reagent contained in the reagent information; and if the alarm signal is not in the effective state, generating third alarm information.
In the implementation, the radio frequency chip on the kit can also be used for storing the reagent information of the reagent in the kit; the radio frequency card reader can also be used for reading reagent information stored by a radio frequency chip on the kit; for example, reagent production time, expiration date, etc.; further, the processor may determine whether the reagent stored in the kit is in a valid state based on the reagent production time and the valid period included in the reagent information; specifically, the failure time of the reagent can be calculated according to the production time and the effective period of the reagent, and then the failure time and the current time can be compared, so that whether the reagent is in an effective state or not can be determined. If the first alarm information is not in the effective state, generating third alarm information; for example, the third alarm information may be "reagent has failed" or the like; if in an active state, the next step can be continued.
By way of example, if the current time is 2022, 11, 23; if the reagent production time included in the read reagent information is 2022, 11, 15 and the validity period is 10, the reagent dead time may be calculated as 2022, 11, 26 and the dead time may be compared with the current time, for example, the dead time may be subtracted from the current time, that is 20221123-20221126 = -3, and the result is negative, that is, it may be determined that the reagent is not in a valid state.
If the reagent production time included in the read reagent information is 2022, 11 and 1, and the expiration date is 10, the expiration date of the reagent can be calculated to be 2022, 11 and 11, and the expiration date is subtracted from the current time, i.e., 20221123-20221111 =12, so that the reagent can be determined to be in an effective state.
Here, the processor can judge whether the reagent is in an effective state based on the reagent information stored by the radio frequency chip on the reagent kit read by the radio frequency card reader, so that the effectiveness of the reagent is ensured, and the accuracy of the reagent reaction result is improved.
In a possible embodiment, the processor is further configured to determine, based on the identification information included in the reagent information, whether the reagent stored in the kit has been used; if yes, fourth alarm information is generated.
In particular, the processor may be further configured to determine whether the reagent stored in the kit has been used based on the identification information included in the reagent information; illustratively, when the identification information is 0, it indicates that the reagent is not used; when the identification information is 1, indicating that the reagent has been used; if the read reagent information is 0, determining that the reagent stored in the reagent kit is not used, and continuing the next step; if the read reagent information is 1, determining that the reagent stored in the reagent kit is used, and generating fourth alarm information; for example, the fourth alarm information may be "reagent used" or the like.
In consideration of the fact that the used reagent is polluted, the processor judges whether the reagent stored in the kit is used or not, if yes, fourth warning information is generated, accuracy of a reagent reaction result can be guaranteed, and reagent reaction efficiency is improved.
In one possible embodiment, referring to fig. 3, the reagent reaction apparatus further comprises: a syringe pump 15; a syringe pump 15 for injecting or extracting the reagent into or from the kit body of the kit.
In practice, the reagent reaction apparatus may further comprise a syringe pump in order to obtain a reagent from the kit more conveniently; when the piston of the injection pump moves in a direction away from the kit, the injection pump can extract the reagent from the kit body of the kit; when the piston of the syringe pump moves in a direction approaching the reagent cartridge, the syringe pump can inject the reagent into the reagent cartridge body of the reagent cartridge.
Here, by installing the syringe pump on the reagent reaction apparatus, the reagent can be conveniently extracted from the reagent box body of the reagent box, or the reagent can be injected into the reagent box body of the reagent box, thereby improving the working efficiency of the reagent reaction apparatus.
In one possible embodiment, referring to fig. 3, the reagent reaction apparatus further comprises: a conduit 16, the conduit 16 being detachably connected to the syringe pump 15; a conduit 16 for transporting reagents pumped by the syringe pump.
In practice, the reagent reaction device may further comprise a conduit, which may be detachably connected to the syringe pump, in order to allow transfer of the reagents to the reaction site after the syringe pump has extracted the reagents from the cartridge body of the kit.
Here, the catheter is detachably connected with the syringe pump, and the catheter can be used for conveying the reagent pumped by the syringe pump so that the reagent reaction can be carried out later, and the working efficiency of the reagent reaction equipment is improved.
In one possible embodiment, referring to fig. 4, the reagent reaction apparatus further comprises: a display 17 connected to the processor;
and a processor for controlling the display 17 to display the alarm information after generating the alarm information, wherein the alarm information includes at least one of the first alarm information, the second alarm information, the third alarm information, and the fourth alarm information.
In practice, the reagent reaction device may further comprise a display coupled to the processor; the processor can control the display to display the alarm information after generating the alarm information; here, the alarm information may include at least one of: the reagent kit includes first alarm information indicating that the reagent kit is not adapted to the reagent reaction apparatus, second alarm information indicating that there is a mismatch between the plurality of types of reagent kits, third alarm information indicating that the reagent stored in the reagent kit is not in a valid state, and fourth alarm information indicating that the reagent stored in the reagent kit has been used. That is, after the processor generates any alarm information, the display is controlled to display the alarm information; for example, after the processor generates the first alert information, the display may be controlled to show "the kit is not adapted to the reagent reaction device".
Here, through linking to each other the display with the treater, can control the display to demonstrate alarm information after the treater generates alarm information to can in time point out the staff when abnormal conditions appears, ensure that reagent reaction can normally go on, can improve reagent reaction result's accuracy.
In another possible embodiment, referring to fig. 5, the reagent reaction apparatus further comprises: a voice player 18 coupled to the processor, and/or a warning light 19 coupled to the processor.
The processor is used for controlling the voice player 18 to play the alarm information after the alarm information is generated and/or controlling the alarm lamp 19 to flash.
When the method is implemented, the display is considered to only prompt the staff in a mode of displaying the alarm information, and the situation that the staff does not find the alarm information exists; thus, the reagent reaction device may further comprise a voice player connected to the processor, or may further comprise an alarm lamp connected to the processor, or may further comprise a voice player and an alarm lamp connected to the processor. Thus, the processor may control the voice player to play the alarm information after the alarm information is generated, for example, the processor may control the voice player to play "mismatch between kits" or may play the sound of "beep" after the second alarm information is generated; so as to prompt the staff to have abnormal conditions.
Alternatively, the processor may control the warning light to flash after the warning information is generated, for example, the processor may control the warning light to flash a red light or may control the warning light to flash a yellow light after the second warning information is generated; here, the color of the warning lamp may be set according to the reagent condition.
Or the processor can control the voice player to play the alarm information and control the alarm lamp to flash after generating the alarm information.
Here, through linking to each other voice player and/or warning light with the treater, can be after the treater generates alarm information, control voice player broadcast alarm information and/or, control warning light glimmers to can in time indicate the staff when abnormal conditions appears, guarantee reagent reaction can normally go on, can improve reagent reaction result's accuracy.
Based on the same conception, the present disclosure also provides a kit 13, the kit 13 comprising: a radio frequency chip 14.
The radio frequency chip 14 is used for storing chip information so that a radio frequency card reader on the reagent reaction device can read the chip information, and a processor on the reagent reaction device can judge whether the reagent kit is suitable for the reagent reaction device or not based on the read chip information.
In practice, the kit may include a radio frequency chip that may be used to store chip information, e.g., the chip information may indicate the type of kit; so that the radio frequency card reader on the reagent reaction device can read the chip information, and further, the processor on the reagent reaction device can judge whether the reagent kit is suitable for the reagent reaction device or not based on the chip information read by the radio frequency card reader.
Here, through installing the radio frequency chip on the kit, utilize the radio frequency chip to store the chip information, the information capacity stored is great, and install the radio frequency chip on the kit, not fragile and pollute, in order to guarantee the validity of the information; meanwhile, the radio frequency chip is arranged on the reagent kit, chip information is automatically read through the radio frequency card reader, the read chip information is identified through the processor, whether the reagent kit is suitable for the reagent reaction equipment or not is not required to be judged manually, and the working efficiency of the reagent reaction equipment is improved.
In a possible embodiment, referring to fig. 6, the kit 13 further comprises: a kit body 131 and a kit upper cover 132; the reagent box upper cover 132 is placed on the reagent box body 131; the kit body 131 is used for storing reagents.
When the kit is implemented, the kit can further comprise a kit body and a kit upper cover, the kit body can be used for storing the reagent, and the kit upper cover can be placed on the kit body.
In the specific implementation, referring to fig. 7, a hole may be formed in the upper cover of the kit, and the syringe pump may be inserted into the hole, so that the reagent may be extracted from the kit body by using the syringe pump without opening the upper cover of the kit, thereby avoiding the reagent from being polluted.
In the implementation, if the blood or saliva of the target object needs to be detected, a blood sample or saliva sample of the target object can be obtained, and then the processed sample to be detected can be stored in the kit body.
Here, the kit body that the kit includes can deposit reagent, and the kit upper cover can prevent on the kit body, can be better protection reagent not contaminated for the accuracy of the reagent reaction result that obtains is higher.
In one possible embodiment, a chip holder may be used instead of the kit and the sample chip may be placed on the chip holder, see the chip holder shown in fig. 8; at this time, the sample chip may be a biochip, i.e., the sample chip may include sample components of a sample to be detected, such as biological components of deoxyribonucleic Acid (Deoxyribonucleic Acid, DNA), ribonucleic Acid (RNA), polypeptides, proteins, and the like; the sample chip can also store chip information, acquisition time of a sample to be detected, object identification information corresponding to the sample to be detected and the like; for example, the chip information may include chip flux information, chip model information, etc., and the object identification information may include the name, sex, identification number, etc. of the object.
In the specific implementation, under the condition that the chip clamping device and at least one reagent kit are placed in the accommodating part of the reagent reaction equipment and the processor in the reagent reaction equipment does not generate alarm information, the processor can control the injection pump to pump the reagent stored in the at least one reagent kit and convey the reagent to the sample chip through the catheter; further, the reaction can be performed based on the sample components included in the sample chip and the reagent, and the reagent reaction result can be obtained.
Finally, it should be noted that: the foregoing examples are merely specific embodiments of the present disclosure, and are not intended to limit the scope of the disclosure, but the present disclosure is not limited thereto, and those skilled in the art will appreciate that while the foregoing examples are described in detail, it is not limited to the disclosure: any person skilled in the art, within the technical scope of the disclosure of the present disclosure, may modify or easily conceive changes to the technical solutions described in the foregoing embodiments, or make equivalent substitutions for some of the technical features thereof; such modifications, changes or substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the disclosure, and are intended to be included within the scope of the present disclosure. Therefore, the protection scope of the present disclosure shall be subject to the protection scope of the claims.

Claims (10)

1. A reagent reaction apparatus, comprising: the device comprises a processor, a radio frequency card reader and a containing component, wherein the containing component is used for containing the kit; the kit is provided with a radio frequency chip which is used for storing chip information corresponding to the radio frequency chip;
the radio frequency card reader is used for reading the chip information of the radio frequency chip on the kit;
the processor is used for judging whether the kit is suitable for the reagent reaction equipment or not based on the chip information read by the radio frequency card reader, and if so, the processor reacts based on the reagent stored in the kit to obtain a reagent reaction result;
the reagent reaction apparatus further includes: the catheter is detachably connected with the injection pump;
the injection pump is used for injecting the reagent into the kit body of the kit or extracting the reagent from the kit body;
the catheter is used for conveying the reagent pumped by the injection pump.
2. The reagent reaction apparatus of claim 1, wherein the processor is further configured to: and generating first alarm information when the reagent kit is not matched with the reagent reaction equipment.
3. The reagent reaction apparatus according to claim 1, wherein in the case where the accommodating member accommodates a plurality of types of reagent cartridges, the radio frequency reader is further configured to read chip information of the radio frequency chip on each of the plurality of types of reagent cartridges, respectively;
the processor is further configured to determine whether the multiple types of kits are matched based on chip information of the radio frequency chip on each kit, and if the multiple types of kits are not matched, generate second alarm information.
4. The reagent reaction apparatus according to claim 3, wherein the processor, when judging whether or not the plurality of types of the reagent cartridges match based on the chip information of the radio frequency chip on each of the reagent cartridges, is configured to:
and judging whether the plurality of kits are matched or not based on the chip flux information and/or the chip model information in the chip information.
5. The reagent reaction apparatus of claim 1, wherein the radio frequency chip on the kit is further configured to store reagent information of reagents in the kit;
the radio frequency card reader is also used for reading the reagent information stored by the radio frequency chip on the kit;
the processor is further used for judging whether the reagent stored in the kit is in a valid state or not based on the reagent production time and the valid period contained in the reagent information; and if the alarm signal is not in the effective state, generating third alarm information.
6. The reagent reaction apparatus according to claim 5, wherein the processor is further configured to determine whether or not the reagent stored in the reagent cartridge has been used based on the identification information contained in the reagent information; if yes, fourth alarm information is generated.
7. The reagent reaction apparatus according to any one of claims 1 to 6, further comprising: a display coupled to the processor;
the processor is used for controlling the display to display the alarm information after the alarm information is generated, wherein the alarm information comprises at least one of first alarm information, second alarm information, third alarm information and fourth alarm information.
8. The reagent reaction apparatus according to any one of claims 1 to 6, further comprising: a voice player connected with the processor and/or an alarm lamp connected with the processor;
the processor is used for controlling the voice player to play the alarm information after the alarm information is generated and/or controlling the alarm lamp to flash.
9. A kit, characterized in that the kit comprises a radio frequency chip;
the radio frequency chip is used for storing chip information so that a radio frequency card reader on the reagent reaction device can read the chip information, and a processor on the reagent reaction device can judge whether the reagent kit is suitable for the reagent reaction device or not based on the read chip information.
10. The kit of claim 9, further comprising: a kit body and a kit upper cover; the upper cover of the kit is placed on the kit body; the kit body is used for storing the reagent.
CN202223526516.9U 2022-12-22 2022-12-22 Reagent reaction equipment and kit Active CN219642259U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223526516.9U CN219642259U (en) 2022-12-22 2022-12-22 Reagent reaction equipment and kit

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223526516.9U CN219642259U (en) 2022-12-22 2022-12-22 Reagent reaction equipment and kit

Publications (1)

Publication Number Publication Date
CN219642259U true CN219642259U (en) 2023-09-05

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