CN219608933U - Detection device - Google Patents

Abstract

The utility model discloses a detection device, which relates to the technical field of immunodetection and comprises a shell, wherein a test strip is fixedly arranged in the shell, a result window corresponding to the test strip is arranged in the middle of the shell, a sample adding window corresponding to the test strip is arranged at one end of the shell, a diluent bag is arranged at the outer side of the shell between the result window and the sample adding window, diluent is filled in the diluent bag, a colloidal gold pad is arranged at the inner side of the diluent bag shell and is contacted with the test strip, an opening is arranged on a shell between the diluent bag and the colloidal gold pad, and a piercing structure corresponding to the opening is arranged at the inner side wall of the diluent bag. The scheme improves the binding rate of the antigen in the sample and the labeled antibody on the test strip, improves the detection sensitivity, reduces the operation steps in actual operation, and solves the problem of low detection efficiency and troublesome steps in the prior art.

Description

Detection device

Technical Field

The utility model relates to the technical field of immunodetection, in particular to a detection device.

Background

Immunochromatography is a rapid diagnosis technology developed abroad in recent years, and the principle is that a specific antibody is firstly fixed on a certain zone of a nitrocellulose membrane, after one end of the dried nitrocellulose is immersed in a sample (urine or serum), the sample moves forward along the membrane due to capillary action, when the sample moves to a zone fixed with the antibody, the corresponding antigen in the sample is specifically combined with the antibody, and if the zone is dyed by immune colloidal gold or immune enzyme, certain color can be displayed to provide qualitative or semi-quantitative detection data of the sample, so that specific immunodiagnosis is realized. Compared with the conventional diagnosis method, the technology has high analysis speed, and the whole detection process only needs 5-30 minutes. The operation is simple and convenient, no other instrument is needed, no professional is needed, and the condition is provided for real-time in-situ detection. The detection sample has various types, and can be used for preparing trace solutions for blood, saliva, food, water quality, soil and the like in medical treatment, sanitation, food safety and environmental detection.

The Chinese patent of utility model with publication number CN212964985U discloses an immunochromatography detection device, which comprises an upper shell and a lower shell, wherein the upper shell is connected with the lower shell in a clamping way, a clamping groove is formed between the upper shell and the lower shell, a test strip is arranged in the clamping groove, a result window is arranged on the upper surface of the upper shell, a diluting liquid block groove is formed in one side of the result window, a diluting liquid block is arranged in the diluting liquid block groove, a leak hole is formed in the middle of the diluting liquid block, a colloidal gold pad fixing groove is formed in the middle of the diluting liquid block groove, and a colloidal gold pad is arranged in the colloidal gold pad fixing groove. The utility model uses a two-step method aiming at certain methodologies, improves the binding rate of substances (antigen/antibody) to be detected in a sample and the coated antibody/antigen on the test strip, and improves the detection sensitivity. However, in the above-mentioned scheme, a plurality of processes are required in actual use, and especially, after the sample is added, the diluent is required to be added again, and this operation increases the operation steps of detection, reduces the efficiency, and also causes invariance to the operation when being added again.

Disclosure of Invention

In view of the above-mentioned shortcomings in the background art, the present utility model provides a detection device to solve the above-mentioned problems.

The technical scheme of the utility model is realized as follows: the utility model provides a detection device, including the shell, the shell internal fixation is equipped with the test strip, the result window that corresponds with the test strip has been seted up at the shell middle part, shell one end is equipped with the sample that corresponds with the test strip and adds the window, the shell outside between result window and the sample addition window is equipped with the dilution liquid bag, the intussuseption of dilution liquid bag is filled with the diluent, dilution liquid bag shell inboard is equipped with the colloidal gold pad, the contact of colloidal gold pad and test strip, be equipped with the opening on the casing between dilution liquid bag and the colloidal gold pad, dilution liquid bag inside wall is equipped with the piercing structure that corresponds with the opening.

Preferably, the shell comprises an upper cover and a lower shell, the upper cover and the lower shell are connected in a sealing way, and the result window, the sample adding window, the dilution liquid bag and the colloidal gold pad are all fixed with the upper cover, and the test strip is fixedly arranged in the lower shell.

Preferably, the result window is an inverted trapezoid window.

Preferably, the sample adding window is a window with an arc-shaped groove structure.

Preferably, the dilution liquid bag is a soft rubber bag.

Preferably, the puncture structure is arranged on the inner wall of one side, far away from the opening, of the diluent bag, and comprises a fixing plate, and the fixing plate is provided with a spike corresponding to the opening.

Preferably, the opening is a rectangular opening.

Preferably, the colloidal gold pad is rectangular and annular and is arranged corresponding to the rectangular opening.

The utility model has the beneficial effects that: according to the scheme, the dilution liquid bag is arranged on the shell in advance, the dilution function can be configured on the detection device during production, the secondary addition operation is not needed during on-site detection, the dilution liquid bag is pierced by directly utilizing the piercing structure, the dilution liquid in the dilution liquid bag enters the shell through the opening of the shell and is contacted and fused with the colloidal gold pad to form a liquid state, the reaction is finally leaked to the test strip, the reaction result is presented in the result window, the binding rate of the antigen in the sample and the labeled antibody on the test strip is improved, the detection sensitivity is improved, the operation steps during actual operation are reduced, and the problem of low detection efficiency and troublesome steps in the prior art is solved.

Drawings

In order to more clearly illustrate the embodiments of the present utility model, the drawings that are required for the description of the embodiments will be briefly described below, it being apparent that the drawings in the following description are only some embodiments of the present utility model and that other drawings may be obtained from these drawings without inventive effort for a person of ordinary skill in the art.

FIG. 1 is a schematic perspective view of the present utility model;

FIG. 2 is a schematic view of the internal structure of the housing of the present utility model;

FIG. 3 is a schematic view of the internal structure of the dilution liquid bag according to the utility model.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without any inventive effort, are intended to be within the scope of the utility model.

As shown in fig. 1 and 2, embodiment 1, a detection device, including shell 1, shell 1 internal fixation is equipped with test strip 2, the result window 3 that corresponds with test strip 2 has been seted up at shell 1 middle part, shell 1 one end is equipped with the sample that corresponds with test strip 2 and adds window 4, the shell 1 outside between result window 3 and the sample is added window 4 is equipped with diluent bag 5, diluent bag 5 intussuseption is filled with diluent, diluent bag 5 shell inboard is equipped with colloidal gold pad 6, colloidal gold pad 6 and test strip 2 contact, be equipped with the opening on the casing between diluent bag 5 and the colloidal gold pad 6, diluent bag 5 inside wall is equipped with the piercing structure that corresponds with the opening. Through setting up the dilution liquid bag on the shell in advance, just dispose the dilution function on detection device when production, need not to carry out the secondary when the field test and add the operation, directly utilize piercing structure to puncture the dilution liquid bag, make the diluent in the dilution liquid bag get into the shell through the opening of shell and contact with the colloidal gold pad and fuse into liquid, finally leak and react on the test paper strip, the reaction result presents at the result window, the binding rate of antigen and the mark antibody on the test paper strip in this scheme has improved the sample, the detection sensitivity has been improved, the operation step when having reduced actual operation simultaneously, the problem of the low step trouble of detection efficiency among the prior art has been solved.

In embodiment 2, on the basis of embodiment 1, the outer shell 1 comprises an upper cover 7 and a lower shell 8, the upper cover 7 and the lower shell 8 are in sealing connection, and the result window 3, the sample adding window 4, the dilution liquid bag 5 and the colloidal gold pad 6 are all fixed with the upper cover 7, and the test strip 2 is fixedly arranged in the lower shell 8. The result window 3 is a window with an inverted trapezoid structure. The sample addition window 4 is a window with an arc-shaped groove structure. The dilution liquid bag 5 is a soft rubber bag.

As shown in fig. 3, in embodiment 3, in addition to embodiment 2, a piercing structure is provided on the inner wall of the dilution liquid bag on the side far away from the opening, the piercing structure includes a fixing plate 9, and a spike 10 corresponding to the opening is provided on the fixing plate 9. The opening is a rectangular opening. The colloidal gold pad 6 is rectangular and annular and is arranged corresponding to the rectangular opening.

When the test strip is used, firstly, a sample is dripped on the sample adding window, after the test strip is waited to be absorbed, the diluting liquid bag is pressed, the tip of the penetrating structure in the diluting liquid bag penetrates through the side wall of the position corresponding to the opening, after the penetrating structure is loosened, the tip is separated from the diluting liquid bag, the diluting liquid in the diluting liquid bag enters the shell through the hole penetrated by the tip and the opening on the shell, is combined with the colloidal gold pad on the inner side of the upper cover to form liquid, is absorbed by the test strip, reacts with the sample liquid, and finally shows a result at the position of the result window.

The foregoing description of the preferred embodiments of the utility model is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the utility model.

Claims (8)

1. A detection device, characterized in that: including shell (1), shell (1) internal fixation is equipped with test strip (2), shell (1) middle part has seted up result window (3) that correspond with test strip (2), shell (1) one end is equipped with sample interpolation window (4) that correspond with test strip (2), the shell (1) outside between result window (3) and sample interpolation window (4) is equipped with dilution liquid bag (5), dilution liquid bag (5) intussuseption is filled with the diluent, dilution liquid bag (5) shell inboard is equipped with colloidal gold pad (6), colloidal gold pad (6) are contacted with test strip (2), be equipped with the opening on the casing between dilution liquid bag (5) and the colloidal gold pad (6), dilution liquid bag (5) inside wall is equipped with the puncture structure that corresponds with the opening.

2. A test device according to claim 1, wherein: the shell (1) comprises an upper cover (7) and a lower shell (8), the upper cover (7) and the lower shell (8) are connected in a sealing mode, and a result window (3), a sample adding window (4), a dilution liquid bag (5) and a colloidal gold pad (6) are fixed with the upper cover (7), and the test strip (2) is fixedly arranged in the lower shell (8).

3. A test device according to claim 2, wherein: the result window (3) is a window with an inverted trapezoid structure.

4. A test device according to claim 3, wherein: the sample adding window (4) is a window with an arc-shaped groove structure.

5. A test device according to claim 4, wherein: the dilution liquid bag (5) is a soft rubber bag.

6. A test device according to claim 5, wherein: the puncture structure is arranged on the inner wall of one side, far away from the opening, of the diluent bag and comprises a fixing plate (9), and a spike (10) corresponding to the opening is arranged on the fixing plate (9).

7. A test device according to claim 6, wherein: the opening is a rectangular opening.

8. A test device according to claim 7, wherein: the colloidal gold pad (6) is rectangular and annular and is arranged corresponding to the rectangular opening.