CN219602252U - Storage tube conveying mechanism, object to be detected loading device and nucleic acid detection all-in-one machine - Google Patents

Abstract

The utility model provides a storage tube transmission mechanism, an object to be detected loading device and a nucleic acid detection integrated machine, wherein the storage tube transmission mechanism comprises: the movable frame is provided with a first bearing position and a second bearing position which are used for placing the storage tube at intervals, and the first bearing position of the movable frame corresponds to the cover opening piece; the clamping assembly comprises a first clamping piece and a second clamping piece, wherein the first clamping piece and the second clamping piece are used for clamping the storage tube, the first clamping piece is arranged on the movable frame corresponding to the first bearing position, the second clamping piece is arranged on the movable frame corresponding to the second bearing position, and when the first clamping piece clamps the storage tube on the first bearing position, and the second clamping piece clamps the storage tube on the second bearing position, the clamping force of the first clamping piece is larger than that of the second clamping piece. According to the technical scheme provided by the utility model, the problem of high cost of the clamping piece of the storage tube transmission mechanism of the nucleic acid detection equipment in the prior art can be solved.

Description

Storage tube conveying mechanism, object to be detected loading device and nucleic acid detection all-in-one machine

Technical Field

The utility model relates to the technical field of nucleic acid detection, in particular to a storage tube conveying mechanism, an object to be detected loading device and a nucleic acid detection integrated machine.

Background

In clinical laboratory, the collected sample is usually stored in a storage tube, and the sample in the storage tube is detected by a nucleic acid detecting apparatus.

In the prior art, the storage tube has various types, such as a sample tube with a tube cap, a sample tube without a tube cap, and a sample tube with different tube diameters, when the nucleic acid detecting apparatus transports the storage tube by using the storage tube transporting mechanism, the storage tube is usually placed on a carrying position of the storage tube transporting mechanism and clamped and fixed by a clamping member, but the clamping member of the storage tube transporting mechanism in the prior art applies the same clamping force to the storage tube with different types, so that the clamping member of the storage tube transporting mechanism of the nucleic acid detecting apparatus in the prior art has higher cost.

Disclosure of Invention

The utility model provides a storage tube transmission mechanism, an object to be detected loading device and a nucleic acid detection integrated machine, which are used for solving the problem that a clamping piece of the storage tube transmission mechanism of nucleic acid detection equipment in the prior art is high in cost.

According to an aspect of the present utility model, there is provided a storage tube transfer mechanism comprising: the movable frame is provided with a first bearing position and a second bearing position which are used for placing the storage tube at intervals, and the first bearing position of the movable frame corresponds to the cover opening piece; the clamping assembly comprises a first clamping piece and a second clamping piece, wherein the first clamping piece and the second clamping piece are used for clamping the storage tube, the first clamping piece is arranged on the movable frame corresponding to the first bearing position, the second clamping piece is arranged on the movable frame corresponding to the second bearing position, and when the first clamping piece clamps the storage tube on the first bearing position, and the second clamping piece clamps the storage tube on the second bearing position, the clamping force of the first clamping piece is larger than that of the second clamping piece.

Further, the clamping assembly further comprises a first driving piece and a sliding seat, wherein the sliding seat is arranged on the movable frame and located on one side of the first bearing position and one side of the second bearing position, and the first driving piece is in driving connection with the sliding seat so as to drive the sliding seat to move relative to the first bearing position and the second bearing position.

Further, the first clamping piece includes first spring and first clamping piece, and first clamping piece is located the one side that is close to the sliding seat of first position that bears, and the both ends of first spring are connected with first clamping piece and sliding seat respectively, and the second clamping piece includes second spring and second clamping piece, and the second clamping piece is located the one side that is close to the sliding seat of second position that bears, and the both ends of second spring are connected with second clamping piece and sliding seat respectively, and when the storage tube on the first position that bears of first clamping piece clamp, and the second clamping piece clamp the storage tube on the second position that bears, the elastic force of first spring is greater than the elastic force of second spring.

Further, the clamping assembly further comprises: the first driving piece is in driving connection with the guide disc to drive the guide disc to rotate around the center of the guide disc, the vertical axis of the guide disc penetrates through the center of a connecting line of the first bearing position and the second bearing position, an arc-shaped groove is formed in the guide disc, and the distance between the first end of the arc-shaped groove and the center of the guide disc is smaller than the distance between the second end of the arc-shaped groove and the center of the guide disc; the upper end of the transmission rod is fixedly connected with the sliding seat, the lower end of the transmission rod stretches into the arc-shaped groove, the moving frame is provided with a track, the sliding seat is movably arranged on the track along the extending direction of the track, and the lower end of the transmission rod moves along the extending direction of the arc-shaped groove in the process that the guide disc moves relative to the moving frame so as to drive the sliding seat to move relative to the first bearing position and the second bearing position.

Further, the first clamping piece further comprises a first connecting column, one end of the first connecting column is fixedly connected with the first clamping block, the first connecting column is movably arranged on the sliding seat in a penetrating mode, and the first spring is sleeved on the first connecting column; the second clamping piece further comprises a second connecting column, one end of the second connecting column is fixedly connected with the second clamping block, the second connecting column movably penetrates through the sliding seat, and the second spring is sleeved on the second connecting column.

Further, the clamping assembly comprises two sliding seats, the first clamping piece comprises two first springs and two first clamping blocks, the second clamping piece comprises two second springs and two second clamping blocks, and the two sliding seats, the two first springs, the two first clamping blocks, the two second springs and the two second clamping blocks are symmetrically arranged by taking the connecting line of the first bearing position and the second bearing position as a symmetrical line.

Further, the clamping assembly further comprises an anti-skid block, and the anti-skid block is arranged on one side of the first clamping piece, which faces the first bearing position; and/or the storage tube conveying mechanism further comprises a base, and the movable frame is movably arranged on the base.

According to another aspect of the present utility model, there is provided an object loading device, including: the cover opening mechanism comprises a cover opening piece capable of opening and closing the cover of the storage tube; a filling mechanism including a filling member capable of filling the storage material in the storage tube into the reaction vessel; the storage tube conveying mechanism comprises a moving frame, a storage tube conveying mechanism and a storage tube conveying mechanism, wherein the moving frame is provided with a cover opening position and a filling position, the moving frame can move between the cover opening position and the filling position, when the moving frame moves to the cover opening position, a first bearing position of the moving frame corresponds to a cover opening part, when the moving frame moves to the filling position, the moving frame is positioned at a position corresponding to the filling mechanism, and the storage tube conveying mechanism is provided by the storage tube conveying mechanism.

Further, the analyte loading device further includes: the storage mechanism comprises a storage bin for storing storage tubes; the transfer mechanism comprises a transfer piece capable of transferring the storage tube between the movable frame and the storage mechanism, the movable frame is further provided with a loading position, the movable frame can move among the loading position, the uncovering position and the filling position, when the movable frame moves to the loading position, the movable frame is located at a position corresponding to the storage mechanism, and the transfer piece can transfer the storage tube between the movable frame and the storage bin so as to load the storage tube on a first bearing position and/or a second bearing position of the movable frame.

Further, the storage tube comprises a sample tube and a quality control tube, and the storage bin comprises a sample storage bin for storing the sample tube and a quality control product storage bin for storing the quality control tube; the sample storage bin and the quality control product storage bin are independently arranged; the quality control product storage bin and the cover opening mechanism are respectively positioned at two sides of the sample storage bin, and the filling mechanism is positioned at one side of the cover opening mechanism far away from the sample storage bin.

According to still another aspect of the present utility model, there is provided a nucleic acid detecting integrated machine including a reagent preparing apparatus for preparing an extraction reagent and an amplification reagent, a sample extracting apparatus for extracting an analyte from a sample and combining the analyte with the amplification reagent to form a measurement mixture, and an amplification detecting apparatus for performing amplification detection on the measurement mixture, the sample extracting apparatus including the sample loading apparatus provided above.

By applying the technical scheme of the utility model, the storage tube conveying mechanism comprises the movable frame and the clamping assembly, and the storage tube is prevented from shaking in the transportation process by arranging the first clamping piece and the second clamping piece on the first bearing position and the second bearing position respectively and clamping the storage tube by the clamping assembly in the transportation process of the movable frame. When the first clamping piece clamps the storage tube on the first bearing position, and the second clamping piece clamps the storage tube on the second bearing position, the clamping force of the first clamping piece is larger than that of the second clamping piece, when the first bearing position of the movable frame corresponds to the uncapping piece, the first clamping piece can be guaranteed to provide enough clamping force, so that the storage tube on the first bearing position can be uncapped normally, and the storage tube on the second clamping piece does not have the uncapping requirement, so that the cost of the clamping assembly can be reduced by reducing the clamping force of the second clamping piece.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the utility model. In the drawings:

fig. 1 shows a schematic structural diagram of an object loading device according to an embodiment of the present utility model;

fig. 2 is a schematic structural view showing an uncovering mechanism and a storage tube conveying mechanism of an object to be tested loading device according to an embodiment of the present utility model;

FIG. 3 is a schematic view showing the structure of a movable rack and a clamping assembly of a storage tube transport mechanism according to an embodiment of the present utility model;

FIG. 4 illustrates a top view of a movable frame and clamping assembly of a storage tube transport mechanism provided in accordance with an embodiment of the present utility model;

FIG. 5 illustrates a side view of a movable carriage and clamping assembly of a storage tube transport mechanism provided in accordance with an embodiment of the present utility model;

fig. 6 is a schematic structural view showing a guide plate of a storage tube conveying mechanism according to an embodiment of the present utility model;

fig. 7 is a schematic structural view of a transfer mechanism of an object loading device according to an embodiment of the present utility model;

FIG. 8 illustrates a top view of a storage tube transport mechanism provided in accordance with an embodiment of the present utility model;

FIG. 9 illustrates a bottom view of a storage tube transport mechanism provided in accordance with an embodiment of the present utility model;

fig. 10 shows a schematic structural diagram of a nucleic acid detecting all-in-one machine according to an embodiment of the present utility model.

Wherein the above figures include the following reference numerals:

10. a storage mechanism; 11. a storage bin; 111. a sample storage bin; 112. a quality control product storage bin;

20. a transfer mechanism; 21. a transfer member;

30. a storage tube transfer mechanism; 31. a moving rack; 311. a first bearing position; 312. a second bearing position; 313. a connecting block; 314. a track; 32. a clamping assembly; 321. a first clamping member; 3211. a first spring; 3212. a first clamping block; 3213. a first connection post; 322. a second clamping member; 3221. a second spring; 3222. a second clamping block; 3223. a second connection post; 323. a first driving member; 324. a sliding seat; 33. a base; 331. a first groove; 332. a second groove; 34. a second driving member; 35. a guide disc; 351. an arc-shaped groove; 36. a transmission rod; 37. an anti-skid block;

40. a cover opening mechanism; 41. a cover opening member;

50. a filling mechanism;

61. a reagent preparing device; 62. an object to be measured extracting device; 621. the object to be measured loading device; 63. amplification detection device.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. The following description of at least one exemplary embodiment is merely exemplary in nature and is in no way intended to limit the utility model, its application, or uses. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

As shown in fig. 1 to 10, an embodiment of the present utility model provides a storage tube conveying mechanism, which includes a movable frame 31 and a clamping assembly 32, a first bearing position 311 and a second bearing position 312 for placing a storage tube are disposed on the movable frame 31 at intervals, the first bearing position 311 of the movable frame 31 can correspond to an uncapping member 41, the clamping assembly 32 includes a first clamping member 321 and a second clamping member 322 for clamping the storage tube, the first clamping member 321 is disposed on the movable frame 31 corresponding to the first bearing position 311, the second clamping member 322 is disposed on the movable frame 31 corresponding to the second bearing position 312, and when the first clamping member 321 clamps the storage tube on the first bearing position 311, and the second clamping member 322 clamps the storage tube on the second bearing position 312, the clamping force of the first clamping member 321 is greater than the clamping force of the second clamping member 322.

By applying the technical scheme of the utility model, the storage tube conveying mechanism comprises the movable frame 31 and the clamping assembly 32, and in the process of transporting the storage tube by the movable frame 31, the storage tube is clamped by the clamping assembly 32 by arranging the first clamping piece 321 and the second clamping piece 322 on the first bearing position 311 and the second bearing position 312 respectively, so that the storage tube is prevented from shaking in the transportation process. When the first clamping member 321 clamps the storage tube on the first carrying position 311, and the second clamping member 322 clamps the storage tube on the second carrying position 312, since the clamping force of the first clamping member 321 is greater than that of the second clamping member 322, when the first carrying position 311 of the movable frame 31 corresponds to the uncapping member 41, the first clamping member 321 can be ensured to provide sufficient clamping force, so that the storage tube on the first carrying position 311 can be uncapped normally, and since the storage tube on the second clamping member 322 does not have the uncapping requirement, the cost of the clamping assembly 32 can be reduced by reducing the clamping force of the second clamping member 322.

And, the first clamping member 321 and the second clamping member 322 are also adapted to clamp storage tubes of different tube diameters during transportation of the storage tubes by the moving frame 31.

As shown in fig. 4, the clamping assembly 32 further includes a first driving member 323 and a sliding seat 324, wherein the sliding seat 324 is disposed on the moving frame 31 and located at one side of the first bearing position 311 and the second bearing position 312, and the first driving member 323 and the sliding seat 324 are in driving connection so as to drive the sliding seat 324 to move relative to the first bearing position 311 and the second bearing position 312.

The sliding seat 324 is disposed on the moving frame 31 and located on one side of the first bearing position 311 and the second bearing position 312, which includes the following two embodiments:

(1) The clamping assembly 32 comprises a sliding seat 324, the sliding seat 324 is positioned on one side of the first bearing position 311 and the second bearing position 312, the clamping assembly 32 further comprises a clamping boss fixedly arranged on the movable frame 31 and positioned on the other side of the first bearing position 311 and the second bearing position 312, when the sliding seat 324 is close to the clamping boss, the first clamping piece 321 and the clamping boss are used for clamping a storage tube on the first bearing position 311, and the second clamping piece 322 and the clamping boss are used for clamping the storage tube on the second bearing position 312;

(2) The clamping assembly 32 includes two sliding bases 324, the first clamping piece 321 has two first clamping portions, the second clamping piece 322 has two second clamping portions, the two sliding bases 324, the two first clamping portions and the two second clamping portions are symmetrically arranged by taking a connecting line of the first bearing position 311 and the second bearing position 312 as a symmetry line, when the two sliding bases 324 are close to each other, the storage tube on the first bearing position 311 is clamped by the two first clamping portions, and the storage tube on the second bearing position 312 is clamped by the two second clamping portions.

As shown in fig. 4, the first clamping member 321 includes a first spring 3211 and a first clamping block 3212, the first clamping block 3212 is located at one side of the first bearing position 311 near the sliding seat 324, two ends of the first spring 3211 are respectively connected with the first clamping block 3212 and the sliding seat 324, the second clamping member 322 includes a second spring 3221 and a second clamping block 3222, the second clamping block 3222 is located at one side of the second bearing position 312 near the sliding seat 324, two ends of the second spring 3221 are respectively connected with the second clamping block 3222 and the sliding seat 324, and when the first clamping member 321 clamps a storage tube on the first bearing position 311, and the second clamping member 322 clamps a storage tube on the second bearing position 312, the elastic force of the first spring 3211 is greater than that of the second spring 3221. The sliding seat 324 is driven by the first driving piece 323 to move relative to the first bearing position 311 and the second bearing position 312, so that the moving frame 31 drives the first clamping block 3212 to clamp the storage tube on the first bearing position 311 through the first spring 3211, the moving frame 31 drives the second clamping block 3222 to clamp the storage tube on the second bearing position 312 through the second spring 3221, the first clamping piece 321 and the second clamping piece 322 are synchronously clamped, and the first spring 3211 and the second spring 3221 can play a buffering role, so that the first clamping piece 321 and the second clamping piece 322 are flexibly clamped.

In this embodiment, the elastic coefficient of the first spring 3211 is greater than that of the second spring 3221, that is, when the first clamping block 3212 clamps the storage pipe on the first loading position 311 and the second clamping block 3222 clamps the storage pipe on the second loading position 312, the elastic force generated by the first spring 3211 is greater than that generated by the second spring 3221 no matter the deformation amount generated by the first spring 3211 is the same as the deformation amount generated by the second spring 3221 or the deformation amount generated by the first spring 3211 is slightly less than the deformation amount generated by the second spring 3221, so that the first clamping member 321 can provide enough clamping force to ensure that the storage pipe on the first loading position 311 can not shake when the storage pipe on the second clamping member 322 is uncapped, and the cost of the clamping assembly 32 can be reduced by reducing the clamping force of the second clamping member 322 because the storage pipe on the second clamping member 322 does not have the uncapping requirement.

In other embodiments, the spring constant of the first spring 3211 is equal to the spring constant of the second spring 3221, the length of the first spring 3211 is greater than the length of the second spring 3221, when the first clamping block 3212 clamps the storage tube on the first carrying position 311 and the second clamping block 3222 clamps the storage tube on the second carrying position 312, since the deformation amount of the first spring 3211 is greater than the deformation amount of the second spring 3221, the spring force generated by the first spring 3211 is greater than the spring force generated by the second spring 3221, so that the first clamping member 321 can provide enough clamping force to ensure that the storage tube on the first carrying position 311 can not shake when uncapping, and since the storage tube on the second clamping member 322 does not have the uncapping requirement, the cost of the clamping assembly 32 can be reduced by reducing the clamping force of the second clamping member 322.

As shown in fig. 5, the clamping assembly 32 further includes a guide plate 35 and a transmission rod 36, the first driving member 323 is in driving connection with the guide plate 35 to drive the guide plate 35 to rotate around the center thereof, the vertical axis of the guide plate 35 passes through the center of the connecting line of the first bearing position 311 and the second bearing position 312, an arc groove 351 is disposed on the guide plate 35, the distance between the first end of the arc groove 351 and the center of the guide plate 35 is smaller than the distance between the second end of the arc groove 351 and the center of the guide plate 35, the upper end of the transmission rod 36 is fixedly connected with the sliding seat 324, the lower end of the transmission rod 36 extends into the arc groove 351, a track 314 is disposed on the moving frame 31, the sliding seat 324 is movably disposed on the track 314 along the extending direction of the track 314, and during the rotation of the guide plate 35 relative to the moving frame 31, the lower end of the transmission rod 36 moves along the extending direction of the arc groove 351 to drive the sliding seat 324 relative to the first bearing position 311 and the second bearing position 312. The first driving piece 323 drives the guide disc 35 to rotate around the center of the guide disc 35, so that the transmission rod 36 moves along the extending direction of the arc-shaped groove 351 to drive the sliding seat 324 to move along the extending direction of the track 314, namely, the first driving piece 323 drives the sliding seat 324 to move relative to the first bearing position 311 and the second bearing position 312 through the guide disc 35 and the transmission rod 36, and the guiding effect of the arc-shaped groove 351 on the transmission rod 36 and the guiding effect of the track 314 on the sliding seat 324 are utilized to improve the transmission reliability of the clamping assembly.

In this embodiment, the clamping assembly 32 further includes a bearing, an inner race of which is disposed at a lower end of the drive rod 36, and an outer race of which is disposed in the arcuate groove 351. With the above-described bearings, the resistance to movement of the drive rod 36 within the arcuate groove 351 is reduced.

As shown in fig. 4, the first clamping member 321 further includes a first connecting post 3213, one end of the first connecting post 3213 is fixedly connected with the first clamping block 3212, the first connecting post 3213 movably penetrates through the sliding seat 324, the first spring 3211 is sleeved on the first connecting post 3213, the second clamping member 322 further includes a second connecting post 3223, one end of the second connecting post 3223 is fixedly connected with the second clamping block 3222, the second connecting post 3223 movably penetrates through the sliding seat 324, and the second spring 3221 is sleeved on the second connecting post 3223. By utilizing the guiding function of the first connecting post 3213 and the second connecting post 3223, the sliding seat 324 drives the first clamping block 3212 and the second clamping block 3222 to move along a straight line, so that the transmission reliability of the clamping assembly is improved.

As shown in fig. 4, the clamping assembly 32 includes two sliding seats 324, the first clamping member 321 includes two first springs 3211 and two first clamping blocks 3212, the second clamping member 322 includes two second springs 3221 and two second clamping blocks 3222, and the two sliding seats 324, the two first springs 3211, the two first clamping blocks 3212, the two second springs 3221 and the two second clamping blocks 3222 are symmetrically arranged with a line connecting the first bearing position 311 and the second bearing position 312 as a symmetry line. With the above structure, the same storage tube can be clamped by the two first clamping blocks 3212, the same storage tube can be clamped by the two second clamping blocks 3222, and the two first clamping blocks 3212 and the two second clamping blocks 3222 are respectively subjected to the buffering action of the two first springs 3211 and the two second springs 3221, so that the storage tube is subjected to symmetrical clamping forces.

Specifically, two ends of one of the first springs 3211 are connected to one of the first clamping blocks 3212 and one of the sliding seats 324, respectively, and two ends of one of the second springs 3221 are connected to one of the first clamping blocks 3212 and one of the sliding seats 324, respectively.

As shown in fig. 4, the clamping assembly 32 further includes a non-slip block 37, and the non-slip block 37 is disposed on a side of the first clamping member 321 facing the first bearing position 311. By adopting the anti-skid block 37, when the cover opening piece 41 rotates to open the storage tube on the first bearing position 311, the anti-skid block 37 is used for contacting the storage tube, so that the storage tube is prevented from rotating relative to the first bearing position 311 in the cover opening process, and the cover opening operation is normally performed.

As shown in fig. 3, the storage tube transfer mechanism further includes a base 33, and the movable frame 31 is movably disposed on the base 33. Through the removal of movable frame 31 at base 33 for the removal of movable frame 31 is more steady, avoids the storage tube to drop in the transportation process, ensures that storage tube transport mechanism's operation is normal.

As shown in fig. 8 and 9, the transmission mechanism further includes a second driving member 34, a connection block 313 is disposed below the moving frame 31, a first groove 331 and a second groove 332 are disposed on the base 33 in parallel, the second driving member 34 is in driving connection with the connection block 313, the connection block 313 is located in the first groove 331 and slides along the extending direction of the first groove 331, and the moving frame 31 is located in the second groove 332 and slides along the extending direction of the second groove 332.

As shown in fig. 1 to 10, another embodiment of the present utility model provides an object loading apparatus 621 including a cap opening mechanism 40, a filling mechanism 50, and a storage tube transfer mechanism 30, the cap opening mechanism 40 including a cap opening member 41 capable of opening and closing a storage tube, the filling mechanism 50 including a filling member capable of filling a storage object in the storage tube into a reaction container, a moving frame 31 of the storage tube transfer mechanism 30 having a cap opening position and a filling position, the moving frame 31 being movable between the cap opening position and the filling position, a first bearing position 311 of the moving frame 31 corresponding to the cap opening member 41 when the moving frame 31 moves to the cap opening position, the moving frame 31 being located at a position corresponding to the filling mechanism 50 when the moving frame 31 moves to the filling position, the storage tube transfer mechanism 30 being the storage tube transfer mechanism provided above. Therefore, the to-be-tested object loading device 621 provided in this embodiment can also ensure that the first clamping member 321 can provide enough clamping force due to the clamping force of the first clamping member 321 being greater than the clamping force of the second clamping member 322, so that the cost of the clamping assembly 32 can be reduced by reducing the clamping force of the second clamping member 322 on the premise that the storage tube on the first carrying position 311 can be normally uncapped, and the storage tube on the second clamping member 322 does not have the uncapping requirement.

As shown in fig. 1, the object loading device 621 further includes a storage mechanism 10 and a transfer mechanism 20, the storage mechanism 10 includes a storage bin 11 for storing storage tubes, the transfer mechanism 20 includes a transfer member 21 capable of transferring storage tubes between the movable frame 31 and the storage mechanism 10, the movable frame 31 further has a loading position, the movable frame 31 is capable of moving between the loading position, a uncapping position, and a filling position, when the movable frame 31 is moved to the loading position, the movable frame 31 is located at a position corresponding to the storage mechanism 10, and the transfer member 21 is capable of transferring storage tubes between the movable frame 31 and the storage bin 11 to load the storage tubes onto the first carrying position 311 and/or the second carrying position 312 of the movable frame 31. The storage tubes are mainly divided into two types, the first type of storage tubes are provided with tube caps, the second type of storage tubes are not provided with tube caps, when the movable frame 31 is moved to the loading position, the transfer member 21 transfers the storage tubes in the storage bin 11 onto the movable frame 31, so that the storage tubes are placed on at least one of the first bearing position 311 and the second bearing position 312, then the movable frame 31 is directly moved to the filling position, and the to-be-detected objects in the storage tubes are filled into the reaction container by using the filling member.

When the movable frame 31 moves to the uncapping position, the first bearing position 311 of the movable frame 31 corresponds to the uncapping member 41, which means that the distance between the movable frame 31 in the uncapping position and the uncapping member 41 is smaller than the movable frame 31 in the filling position or the movable frame 31 in the loading position, so that the uncapping operation can be performed on the storage tube on the movable frame 31 in the uncapping position by using the uncapping member 41; when the movable frame 31 moves to the filling position, the movable frame 31 is located at a position corresponding to the filling mechanism 50, which means that the distance between the movable frame 31 located at the filling position and the filling mechanism 50 is smaller than the movable frame 31 located at the uncovering position or the movable frame 31 located at the loading position, so that the object to be measured in the storage tube located on the movable frame 31 located at the filling position can be sucked by the filling member; when the movable frame 31 is moved to the loading position, the movable frame 31 is located at a position corresponding to the storage mechanism 10, meaning that the distance between the movable frame 31 at the loading position and the storage bin 11 is smaller than the movable frame 31 at the filling position or the movable frame 31 at the uncovering position, so that the storage tube can be transferred between the storage bin 11 and the movable frame 31 at the loading position by the transfer member 21.

The movable frame 31 has the following three working states:

(1) The first bearing position 311 is used for placing a storage tube with a tube cap, and the second bearing position is empty;

(2) The first bearing position 311 and the second bearing position 312 are used for placing a storage tube without a tube cap;

(3) One of the first bearing position 311 and the second bearing position 312 is used for placing a storage tube without a tube cap, and the other is empty.

In the present embodiment, the first bearing position 311 and the second bearing position 312 are disposed at intervals in parallel to the moving direction of the moving frame 31. During the movement of the moving frame 31, the first bearing position 311 and the second bearing position 312 are always moved synchronously.

In addition, in the working state in which one of the first bearing position 311 and the second bearing position 312 is placed with the storage tube without the cap, and the other is empty, it is preferable that the first bearing position 311 is placed with the storage tube without the cap, and the second bearing position is empty, on the one hand, the judgment procedure can be simplified, and on the other hand, when the movable rack 31 is located at the loading position, the first bearing position 311 and the second bearing position 312 are disposed at intervals in the moving direction parallel to the movable rack 31, and the first bearing position 311 is located at the side of the second bearing position 312 facing the uncapping position and the filling position, so that the transportation path of the movable rack 31 between the loading position, the uncapping position, and the filling position can be shortened.

As shown in fig. 1, the storage tube includes a sample tube and a quality control tube, and the storage bin 11 includes a sample storage bin 111 for storing the sample tube and a quality control product storage bin 112 for storing the quality control tube. By storing the quality control product in the quality control tube of the quality control product storage bin 112, the filling mechanism 50, the storage tube transmission mechanism 30 and the transfer mechanism 20 are shared by the extraction of the quality control product and the collection of the sample, so that the degree of automation of loading of the quality control product is improved, the operation procedure of quality control product detection is simplified, and the time consumption of quality control product detection is shortened.

In the present embodiment, the sample storage bin 111 is provided independently of the quality control product storage bin 112. The sample storage bin 111 and the quality control product storage bin 112 are independently arranged, so that pollution between a sample pipe in the sample storage bin 111 and a quality control pipe in the quality control product storage bin 112 can be avoided, the detection accuracy of nucleic acid detection is ensured, and the detection accuracy is improved.

As shown in fig. 1, the quality control product storage bin 112 and the cap opening mechanism 40 are respectively located at two sides of the sample storage bin 111, and the filling mechanism 50 is located at one side of the cap opening mechanism 40 away from the sample storage bin 111. With the above spatial layout, since the filling mechanism 50 is located at the side of the cap opening mechanism 40 far away from the sample storage bin 11, in the process of transporting the sample tube and the quality control tube between the storage mechanism 10 and the filling mechanism 50, the cap opening mechanism 40 can be passed through to perform the cap opening and closing operation on the sample tube and the quality control tube by using the cap opening mechanism 40, so that the moving distance of the moving rack 31 is shortened, the moving time of the moving rack 31 can be shortened on the premise of a certain moving speed of the moving rack 31, the time consumption of sample and quality control extraction can be shortened, and since the quality control storage bin 112 and the cap opening mechanism 40 are located at two sides of the sample storage bin 111 respectively, compared with the distance between the quality control storage bin 112 and the cap opening mechanism 40, the distance between the sample storage bin 111 and the cap opening mechanism 40 is shorter, and in each batch of nucleic acid detection, the number of times of extracting samples in the sample tube is far greater than the number of times of extracting quality control samples in the quality control tube, so that the time consumption of time of extracting samples can be shortened to a great extent by shortening the time consumption of extracting samples, and the time consumption of extracting samples can be shortened, and the work efficiency of the device to be loaded to be improved.

As shown in fig. 1 to 10, a further embodiment of the present utility model provides a nucleic acid detecting integrated machine, which includes a reagent preparing apparatus 61, a sample extracting apparatus 61 for preparing an extracting reagent and an amplifying reagent, and an amplifying detecting apparatus 63, the sample extracting apparatus for extracting an analyte from a sample and combining the analyte with the amplifying reagent to form a measurement mixture, the amplifying detecting apparatus 63 for performing an amplifying detection on the measurement mixture, the sample extracting apparatus including the sample loading apparatus provided above. Therefore, the nucleic acid detecting integrated machine provided in this embodiment can also ensure that the first clamping member 321 can provide enough clamping force due to the clamping force of the first clamping member 321 being greater than the clamping force of the second clamping member 322, so that the cost of the clamping assembly 32 can be reduced by reducing the clamping force of the second clamping member 322 on the premise that the storage tube on the first carrying position 311 can be normally uncapped, because the storage tube on the second clamping member 322 does not have the uncapping requirement.

Specifically, the extraction reagent and the amplification reagent are prepared by the reagent preparing apparatus 61, the extraction reagent and the amplification reagent are transported to the analyte extracting apparatus 62, the analyte extracting apparatus 62 mixes and extracts the sample with the extraction reagent, the analyte and the amplification reagent are combined to form a measurement mixture, the measurement mixture is transported to the amplification detecting apparatus 63, and after the analyte in the measurement mixture is amplified, the measurement mixture is analyzed and detected, thereby obtaining a detection result of the sample.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of exemplary embodiments according to the present utility model. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.

The relative arrangement of the components and steps, numerical expressions and numerical values set forth in these embodiments do not limit the scope of the present utility model unless it is specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective parts shown in the drawings are not drawn in actual scale for convenience of description. Techniques, methods, and apparatus known to one of ordinary skill in the relevant art may not be discussed in detail, but are intended to be part of the specification where appropriate. In all examples shown and discussed herein, any specific values should be construed as merely illustrative, and not a limitation. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further discussion thereof is necessary in subsequent figures.

In the description of the present utility model, it should be understood that the azimuth or positional relationships indicated by the azimuth terms such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal", and "top, bottom", etc., are generally based on the azimuth or positional relationships shown in the drawings, merely to facilitate description of the present utility model and simplify the description, and these azimuth terms do not indicate and imply that the apparatus or elements referred to must have a specific azimuth or be constructed and operated in a specific azimuth, and thus should not be construed as limiting the scope of protection of the present utility model; the orientation word "inner and outer" refers to inner and outer relative to the contour of the respective component itself.

Spatially relative terms, such as "above … …," "above … …," "upper surface at … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial location relative to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "above" or "over" other devices or structures would then be oriented "below" or "beneath" the other devices or structures. Thus, the exemplary term "above … …" may include both orientations of "above … …" and "below … …". The device may also be positioned in other different ways (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

In addition, the terms "first", "second", etc. are used to define the components, and are only for convenience of distinguishing the corresponding components, and the terms have no special meaning unless otherwise stated, and therefore should not be construed as limiting the scope of the present utility model.

The above description is only of the preferred embodiments of the present utility model and is not intended to limit the present utility model, but various modifications and variations can be made to the present utility model by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model should be included in the protection scope of the present utility model.

Claims (11)

1. A storage tube transfer mechanism, the storage tube transfer mechanism comprising:

the storage device comprises a movable frame (31), wherein a first bearing position (311) and a second bearing position (312) for placing a storage tube are arranged on the movable frame (31) at intervals, and the first bearing position (311) of the movable frame (31) can correspond to a cover opening piece (41);

clamping assembly (32), including being used for pressing from both sides tight first clamping piece (321) and second clamping piece (322) of storage tube, first clamping piece (321) corresponds first loading position (311) set up on moving frame (31), second clamping piece (322) corresponds second loading position (312) set up on moving frame (31), when first clamping piece (321) presss from both sides tight storage tube on first loading position (311), just second clamping piece (322) presss from both sides tight when storage tube on second loading position (312), the clamping force of first clamping piece (321) is greater than the clamping force of second clamping piece (322).

2. The storage tube transfer mechanism of claim 1, wherein the clamping assembly (32) further comprises a first driving member (323) and a sliding seat (324), the sliding seat (324) is disposed on the moving frame (31) and located at one side of the first bearing position (311) and the second bearing position (312), and the first driving member (323) is in driving connection with the sliding seat (324) so as to drive the sliding seat (324) to drive the first clamping member (321) and the second clamping member (322) to move relative to the first bearing position (311) and the second bearing position (312).

3. The storage tube transfer mechanism of claim 2, wherein the first clamping member (321) comprises a first spring (3211) and a first clamping block (3212), the first clamping block (3212) is located at a side of the first load-bearing location (311) near the sliding seat (324), two ends of the first spring (3211) are respectively connected with the first clamping block (3212) and the sliding seat (324), the second clamping member (322) comprises a second spring (3221) and a second clamping block (3222), the second clamping block (3222) is located at a side of the second load-bearing location (312) near the sliding seat (324), two ends of the second spring (3221) are respectively connected with the second clamping block (3222) and the sliding seat (324), and the second clamping member (322) stores the elastic force of the second spring (3221) when the first clamping member (321) clamps the storage tube on the first load-bearing location (311) and the second clamping member (322) is loaded with the second spring (3221).

4. A storage tube transfer mechanism as in claim 3, wherein the clamp assembly (32) further comprises:

the first driving piece (323) is in driving connection with the guide disc (35) to drive the guide disc (35) to rotate around the center of the guide disc, the vertical axis of the guide disc (35) passes through the center of a connecting line of the first bearing position (311) and the second bearing position (312), an arc-shaped groove (351) is formed in the guide disc (35), and the distance between the first end of the arc-shaped groove (351) and the center of the guide disc (35) is smaller than the distance between the second end of the arc-shaped groove (351) and the center of the guide disc (35);

the transmission rod (36), the upper end of transmission rod (36) with sliding seat (324) fixed connection, the lower extreme of transmission rod (36) stretches into in arc recess (351), be provided with track (314) on moving frame (31), sliding seat (324) are followed the extending direction of track (314) movably sets up on track (314) guide disc (35) are relative moving frame (31) pivoted in-process, the lower extreme of transmission rod (36) is followed the extending direction of arc recess (351) is removed, so as to drive sliding seat (324) for first bear position (311) with second bear position (312) removal.

5. A storage tube transfer mechanism as claimed in claim 3, wherein,

the first clamping piece (321) further comprises a first connecting column (3213), one end of the first connecting column (3213) is fixedly connected with the first clamping block (3212), the first connecting column (3213) movably penetrates through the sliding seat (324), and the first spring (3211) is sleeved on the first connecting column (3213);

the second clamping piece (322) further comprises a second connecting column (3223), one end of the second connecting column (3223) is fixedly connected with the second clamping block (3222), the second connecting column (3223) movably penetrates through the sliding seat (324), and the second spring (3221) is sleeved on the second connecting column (3223).

6. A storage tube transfer mechanism according to claim 3, wherein the clamping assembly (32) comprises two sliding seats (324), the first clamping member (321) comprises two first springs (3211) and two first clamping blocks (3212), the second clamping member (322) comprises two second springs (3221) and two second clamping blocks (3222), and the two sliding seats (324), two first springs (3211), two first clamping blocks (3212), two second springs (3221) and two second clamping blocks (3222) are symmetrically arranged with respect to a line of symmetry of the first bearing location (311) and the second bearing location (312).

7. The storage tube transfer mechanism of any one of claims 1 to 6, wherein,

the clamping assembly (32) further comprises an anti-skid block (37), and the anti-skid block (37) is arranged on one side of the first clamping piece (321) facing the first bearing position (311); and/or the number of the groups of groups,

the storage tube conveying mechanism further comprises a base (33), and the movable frame (31) is movably arranged on the base (33).

8. An object to be measured loading device, characterized in that the object to be measured loading device comprises:

a cover opening mechanism (40) comprising a cover opening member (41) capable of opening and closing the storage tube;

a filling mechanism (50) including a filling member capable of filling the storage material in the storage tube into the reaction container;

storage tube transfer mechanism (30), a moving rack (31) of the storage tube transfer mechanism (30) has a uncapping position and a filling position, the moving rack (31) is capable of moving between the uncapping position and the filling position, when the moving rack (31) moves to the uncapping position, the first bearing position (311) of the moving rack (31) corresponds to an uncapping member (41), when the moving rack (31) moves to the filling position, the moving rack (31) is located at a position corresponding to the filling mechanism (50), and the storage tube transfer mechanism (30) is the storage tube transfer mechanism according to any one of claims 1 to 7.

9. The specimen loading device according to claim 8, wherein the specimen loading device further comprises:

a storage mechanism (10) comprising a storage bin (11) for storing the storage tubes;

transfer mechanism (20), including can remove frame (31) with transfer piece (21) of storage tube between storage mechanism (10), remove frame (31) still have loading position, remove frame (31) can remove between loading position, uncap position and filling position, when remove frame (31) remove to loading position, remove frame (31) are located in the position corresponding to storage mechanism (10), transfer piece (21) can remove between remove frame (31) with storage bin (11) the storage tube is loaded on first loading position (311) and/or second loading position (312) of remove frame (31).

10. The analyte loading device of claim 9, wherein the device comprises a housing,

the storage tube comprises a sample tube and a quality control tube, and the storage bin (11) comprises a sample storage bin (111) for storing the sample tube and a quality control product storage bin (112) for storing the quality control tube;

the sample storage bin (111) and the quality control product storage bin (112) are independently arranged;

the quality control product storage bin (112) and the cover opening mechanism (40) are respectively located at two sides of the sample storage bin (111), and the filling mechanism (50) is located at one side, far away from the sample storage bin (111), of the cover opening mechanism (40).

11. A nucleic acid detection all-in-one machine, characterized in that the nucleic acid detection all-in-one machine comprises a reagent preparation device (61), a test object extraction device and an amplification detection device (63), the reagent preparation device (61) is used for preparing an extraction reagent and an amplification reagent, the test object extraction device is used for extracting an analyte from a sample and combining the analyte with the amplification reagent to form a measurement mixture, the amplification detection device (63) is used for performing amplification detection on the measurement mixture, and the test object extraction device comprises the test object loading device according to any one of claims 8 to 10.