CN219573626U - Sampling and separating device for detection - Google Patents

Abstract

The utility model discloses a sampling separation device for detection, which comprises a sampling tube, a sampling tube and a sampling tube, wherein the sampling tube is used for quantitatively sucking a sample; the pipe body is hollow and forms a liquid storage cavity for containing diluent, the bottom of the pipe body is provided with a breakable seal, and the top opening of the pipe body is provided with a sealing element; the connecting sleeve is internally provided with an action convex part, a filtering piece is arranged below the action convex part, and a switching cavity is formed at least at the periphery of the action convex part; the connecting sleeve is connected with the lower part of the connecting sleeve; the bottom of the pipe body can be connected with the switching cavity, and the action convex part can open the easy-to-crack seal, so that the liquid in the liquid storage cavity flows to the connecting pipe after passing through the filter element. The utility model has simple structure and convenient operation; after the blood sample is dripped into the device, personnel operation is not needed, a large instrument is not needed, the risk of pollution to the sample is reduced, and the detection accuracy is improved; the method avoids using a centrifugal machine for centrifugation, can quickly separate serum, is convenient for obtaining the processed mixed serum solution, and completes operations such as sampling, dilution, blood separation, sample adding test and the like.

Description

Sampling and separating device for detection

Technical Field

The utility model belongs to the technical field of test strip detection, and particularly relates to a sampling separation device for detection.

Background

The blood detection is one of detection items for disease of patients, and the blood detection needs to be carried out through steps of blood sampling, separation, dilution, test paper detection and the like, and the detection mode is generally that a blood sample is collected by a blood sampling tube and then is put into a centrifuge for separation, so that serum is obtained, the serum is sucked by a quantitative suction tube and is dripped onto a test paper, and the detection is carried out through the chromatographic action of the test paper. However, the conventional detection method has the following disadvantages: 1) The traditional sampling separation device has more accessories and complicated operation steps; 2) The traditional sampling separation mode generally needs to separate serum by virtue of a centrifugal machine, the time for separating serum is long, 3) the serum is taken out by a manual pipette and added into the diluent, so that the operation difficulty is increased, the risk of sample pollution is increased, the accuracy of a detection result is influenced, and the risk of an operator contacting a blood sample of a subject is greatly improved; 4) The traditional sampling and separating device needs more blood sampling samples; 5) After the sampling separation device separates serum, the serum needs to be dripped on the test strip, the operation is more complicated, and the risk of pollution of a blood sample is improved.

Blood consists of plasma and blood cells. Plasma intein (albumin, globulin, fibrinogen, etc.), lipoprotein, inorganic salts, hormones, enzymes, antibodies, cell metabolites, etc. The blood cells include red blood cells, white blood cells and platelets. The physiological and pathological changes of the body often cause changes in blood components, so the detection of blood components is of great clinical significance. When a dry immunofluorescence detection kit is used to detect blood, substances such as red blood cells in whole blood may interfere with the detection result. Such as signal decrease, membrane blockage, false negative, false positive, and the like, which affect the detection sensitivity, accuracy, repeatability, and the like of the kit. When the existing dry detection kit is used for detecting blood, the whole blood and a sample are generally directly dripped on a sample adding hole and a sample pad. Red blood cells are filtered through the sample pad, but because of structural and formulation problems, red blood cells are often not filtered effectively, the detection precision is greatly affected, and the result is greatly different from the serum detection. Or the blood sample which is collected and pumped by the pipettor is put into a centrifuge for separation, so that serum is obtained, then the serum is sucked by using a quantitative suction tube and is dripped onto a test strip, and the test strip is used for detection under the chromatographic action of the test strip.

Disclosure of Invention

In order to overcome the defects of the prior art, the utility model provides the sampling and separating device for detection, which has the advantages of simplified structure, convenience in operation and reduced pollution risk.

The technical scheme adopted for solving the technical problems is as follows: a sample separation apparatus for detection, comprising:

a sampling tube for quantitatively sucking a sample;

the pipe body is hollow and forms a liquid storage cavity for containing diluent, the bottom of the pipe body is provided with a breakable seal, and the top opening of the pipe body is provided with a sealing element;

the connecting sleeve is internally provided with an action convex part, a filtering piece is arranged below the action convex part, and a switching cavity is formed at least at the periphery of the action convex part;

the connecting sleeve is connected with the lower part of the connecting sleeve;

the bottom of the pipe body can be connected with the switching cavity, and the action convex part can open the breakable seal, so that liquid in the liquid storage cavity flows to the faucet after passing through the filter element.

The utility model integrates sampling, dilution, separation and sample adding into one device, and has the advantages of small sampling amount, simple and convenient operation; sample collection and dilution are completed in the same device, namely sample collection and pretreatment are completed in one step, operations such as dilution, cracking and the like of blood are directly completed, a traditional centrifuge is replaced by a blood filtering device by using a filtering piece without secondary treatment of the sample, and sample addition test can be directly performed after filtering.

Further, the test strip and the collection cavity close to the lower end of the test strip are arranged in the joint pipe, and the liquid in the liquid storage cavity flows to the collection cavity after passing through the filter piece and reacts with the test strip.

Further, the adapter tube is made of soft material, and the bottom of the adapter tube is provided with a liquid outlet hole. The design of the adapter tube can accurately control the sample loading quantity.

Further, the bottom of the pipe body and the switching cavity are provided with a first connection state and a second connection state, in the first connection state, the action convex part does not apply external force to the easy-to-crack seal, and in the second connection state, the action convex part upwards pushes up the easy-to-crack seal. The first connection state and the second connection state are arranged, so that the pipe body and the connecting sleeve can be integrally packaged, and follow-up detection operation is convenient.

Further, the sampling tube has a capillary tube and a piercing boss for opening a seal; the sealing element is an aluminum film. The sampling amount by capillary sampling is small, the sample adding amount is accurate, and the operation is simple.

Further, the bottom of the pipe body is in threaded connection with the switching cavity, and the outer wall of the pipe body is provided with an upper blocking rib which can prop against the upper end face of the connecting sleeve; or/and, the top of the connecting pipe is in threaded connection with the lower part of the connecting sleeve, and the outer wall of the connecting pipe is provided with a lower retaining rib which can prop against the lower end face of the connecting sleeve.

Further, the filter element is a filter element, an inner cavity for clamping the filter element is arranged in the connecting sleeve, and at least part of the end face of the connecting pipe is propped against the lower surface of the filter element. The traditional centrifuge is replaced by the blood filtering device by using the filter element, so that the centrifugal precipitated impurities are prevented from being sucked when the sample is sucked, the structure is simplified, the operation is convenient, the blood separation procedure is simplified, the pollution risk is reduced, and the detection efficiency is improved.

Furthermore, the easy-to-crack seal is a sealing piece, the outer ring part connected with the inner wall of the pipe body is of a thin-wall structure, and the inner ring part is of a thick-wall structure; or the inner ring of the easy-to-crack seal is a thin-wall sealing piece.

Further, the action convex part is a cylindrical bulge with a tip, or/and the action convex part is a supporting structure which can prop against the outer ring part.

Further, the side wall of the receiving tube forms a clamping groove for inserting the test strip.

The beneficial effects of the utility model are as follows: 1) The device integrates sampling and separation, and is simple in structure and convenient to operate; after the blood sample is dripped into the device, the professional operation is not needed, a large instrument is not needed, the risk that the sample is polluted and the operator contacts the blood sample of the subject is reduced, and the detection accuracy is improved; 2) The blood sample is filtered by using the filter element, so that centrifugation by using a centrifuge is avoided, serum can be rapidly separated, an operator can conveniently obtain a processed mixed serum solution, and a series of operations such as sampling, dilution, blood separation, sample adding test and the like are completed; 3) Diluting blood by using a diluent to fully dissolve a blood sample, preventing the blood from coagulating too fast, and reducing the blood sampling amount; 4) The quantitative blood collection tube uses a capillary to absorb a blood sample, and the volume (5 mu L-50 mu L) of collected blood is accurately controlled, so that waste is avoided; 5) The device is integrated with sampling, separation and detection, after blood separation, serum directly flows to the collecting cavity, so that the device is in contact reaction with the test strip, no additional operation is needed, the operation is convenient, and the detection efficiency is improved.

Drawings

Fig. 1 is a schematic perspective view of a first embodiment of the present utility model.

Fig. 2 is an exploded view of the first embodiment of the present utility model.

Fig. 3 is a front view of the first embodiment of the present utility model, in which the pipe body and the adapter cavity are in a first connection state.

Fig. 4 is a cross-sectional view of a first embodiment of the present utility model, in which the tube body and the adapter cavity are in a first connection state.

Fig. 5 is a schematic view of a partially enlarged structure of a pipe body and a transfer cavity in a first connection state according to an embodiment of the present utility model.

Fig. 6 is a cross-sectional view of a first embodiment of the present utility model, wherein the tube body and the adapter cavity are in a second connection state.

Fig. 7 is a schematic view of a partially enlarged structure of a pipe body and a transfer cavity in a second connection state according to a first embodiment of the present utility model.

FIG. 8 is a schematic view showing the structure of a sampling tube, a tube body and a connecting sleeve according to a first embodiment of the present utility model.

Fig. 9 is a schematic bottom view of a sampling tube, a tube body and a connecting sleeve according to a first embodiment of the present utility model.

Fig. 10 is a schematic perspective view of a second embodiment of the present utility model.

Fig. 11 is an exploded view of a second embodiment of the present utility model.

Fig. 12 is a front view of a second embodiment of the present utility model, in which the pipe body and the adapter cavity are in a first connection state.

Fig. 13 is a cross-sectional view of a second embodiment of the present utility model, in which the tube body and the adapter cavity are in a first connection state.

Fig. 14 is a cross-sectional view of a second embodiment of the present utility model, in which the shaft and the adapter cavity are in a second connection state.

The device comprises a 1-sampling tube, a 11-capillary tube, a 12-puncture boss, a 2-tube body, a 21-liquid storage cavity, a 22-breakable seal, a 23-sealing piece, a 24-first connection state, a 25-second connection state, a 26-upper blocking rib, a 3-connecting sleeve, a 31-acting convex part, a 311-columnar bulge, a 312-supporting structure, a 32-filtering piece, a 33-switching cavity, a 34-inner cavity, a 4-connecting tube, a 41-liquid outlet hole, a 42-lower blocking rib, a 51-test strip, a 52-collecting cavity and a 53-clamping groove.

Detailed Description

In order to make the present utility model better understood by those skilled in the art, the following description of the technical solutions of the present utility model will be made in detail, but not all embodiments of the present utility model are apparent to some embodiments of the present utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present utility model without making any inventive effort, shall fall within the scope of the present utility model.

Example 1

As shown in fig. 1 to 9, a sample separating device for detection comprises a sampling tube 1 for quantitatively sucking a sample, a tube body 2 having a hollow interior, a connecting sleeve 3, and a receiving tube 4 connected to a lower portion of the connecting sleeve 3.

The inside cavity of pipe shaft 2 forms the stock solution chamber 21 that is used for holding the diluent, and the bottom of pipe shaft 2 has easy crack to seal 22, and the open-ended of pipe shaft 2 is provided with sealing member 23. The inside of the connecting sleeve 3 is provided with an action protrusion 31, a filter 32 is provided below the action protrusion 31, and a transfer chamber 33 is formed, the transfer chamber 33 extending at least at the outer periphery of the action protrusion 31. The bottom of the pipe body 2 can be connected with the transfer cavity 33, and the action protruding part 31 can open the breakable seal 22, so that the liquid in the liquid storage cavity 21 flows to the joint pipe 4 after passing through the filter piece 32, the joint pipe 4 is made of soft materials, the bottom of the joint pipe is provided with a liquid outlet hole 41, the liquid outlet hole 41 can be sealed by an aluminum film, a cap or a cap, and the liquid outlet hole can be sealed integrally or unsealed. When the liquid outlet hole 41 is closed by an aluminum film and the liquid to be detected needs to be dripped out, the aluminum film is only required to be torn; when the liquid outlet 41 is closed by the cap, and the liquid to be detected needs to be discharged, the cap is only required to be unscrewed or buckled according to the forms of screw thread closing or buckle closing of the cap; when the liquid outlet hole 41 is integrally sealed, namely the top end of the liquid outlet hole is sealed and provided with a dent, and the liquid to be detected is required to be dropped out, the liquid outlet hole 41 is only required to be broken along the dent; when the liquid outlet 41 is not closed, the bottom end of the liquid outlet is more slender and similar to a drip tube, and the liquid to be detected needs to be dripped out, the pressure is used to press the bearing tube 4.

The bottom of the pipe body 2 is connected with the transfer cavity 33 and is divided into a first connection state 24 and a second connection state 25. In the first connection state 24, the acting protrusion 31 does not apply an external force to the frangible seal 22, and in this case, the acting protrusion 31 may not contact the frangible seal 22, or the acting protrusion 31 may only lightly contact the frangible seal 22, as shown in fig. 4 and 5. In the second connection state 25, the action protrusion 31 pushes up the frangible seal 22 as shown in fig. 6 and 7. In the present embodiment, the adapter cavity 33 is a hollow portion of the upper portion of the connecting sleeve 3, and the inner wall thereof is provided with an internal thread, and the axial depth is greater than the axial height of the acting protrusion 31.

In this embodiment, the tube body 2 is approximately cylindrical, the top of the sampling tube 1 is closed, the bottom opening is provided with a capillary 11 and a piercing boss 12 for opening a sealing member 23, the piercing boss 12 and the capillary 11 can be combined into one, that is, the opening at the bottom tip of the capillary 11 can be used for sampling, the sealing member 23 can be opened after sampling, or other auxiliary membrane breaking devices can be used for opening the sealing member 23, the sealing member 23 can be an aluminum membrane, the external thread of the sampling tube 1 is matched with the internal thread of the tube body 2 to form, or a circle of elastic sealing strip is arranged at the top of the sampling tube 1 or the tube body 2, when the sampling tube 1 is inserted into the tube body 2, the sealing strip seals the sampling tube 1 and the tube body 2, so that the risk of pollution to the outside of the liquid storage cavity 21 is reduced, and the sealing member 23 is preferably a silica gel sealing strip. The sampling range of the sampling tube 1 is 5ul-50ul, and the sampling volume can be adjusted by replacing capillaries 11 with different lengths, diameters and siphon capacities. After the capillary tube 11 sucks a blood sample, a sealing piece 23 on the top of the tube body 2 is penetrated through an opening at the bottom tip or a penetrating boss 12, when the sealing piece 23 is in threaded fit with the capillary tube 11 and the tube body 2 or is matched with the tube body 2 through a silica gel sealing strip, the sampling tube 1 is directly inserted into the tube body 2, the sampling end of the capillary tube 11 at the bottom of the sampling tube 1 is contacted with the diluent in the liquid storage cavity 21 in the tube body 2, and the mixing of the blood and the diluent is realized by extruding the sampling tube 1, so that the dissolution and dilution of a blood sample are completed.

The filter piece 32 is the filter core, and adapter sleeve 3 inside is equipped with the inner chamber 34 that is used for the card to establish filter piece 32, and inner chamber 34 cooperatees with filter piece 32 surface for filter piece 32 can just in time block into inner chamber 34 and be difficult for dropping. Moreover, at least part of the end face of the adapter tube 4 is abutted against the lower surface of the filter element 32, and also plays a role in supporting the filter element 32 upwards. In this embodiment, the filter element 32 is a microporous filter membrane.

In this embodiment, the bottom of the pipe body 2 is in threaded connection with the adapting cavity 33, and the outer wall of the pipe body 2 is provided with an upper blocking rib 26 which can abut against the upper end face of the connecting sleeve 3, and the upper blocking rib 26 can limit the connection position of the connecting sleeve 3 and the pipe body 2, so as to give a hand feeling prompt for the user that the pipe body 2 and the connecting sleeve 3 are assembled fixedly.

The top of the adapter tube 4 is in threaded connection with the lower part of the connecting sleeve 3, and the outer wall of the adapter tube 4 is provided with a lower blocking rib 42 which can be propped against the lower end face of the connecting sleeve 3, and the lower blocking rib 42 is used for increasing the limit when the adapter tube 4 is screwed, so that the filter element 32 is installed in place and is free from liquid leakage.

Of course, in other embodiments, the connection between the pipe body 2 and the connecting sleeve 3, and the connection between the adaptor pipe 4 and the connecting sleeve 3 may be other structures, such as elastic limit connection in the prior art, and other mechanical connection manners are not limited in particular.

The breakable seal 22 is a sealing piece, and an outer ring portion connected to an inner wall of the pipe body 2 is of a thin-wall structure, an inner ring portion is of a thick-wall structure, or an inner ring portion is of a thin-wall structure, or both the inner ring portion and the outer ring portion are of a thin-wall structure. The action protrusion 31 is a cylindrical protrusion 311 with a tip, or the action protrusion 31 is a cylindrical protrusion 311 with a tip and a propping structure that can be propped against the outer ring portion, or the action protrusion 31 is a propping structure that can be propped against the outer ring portion only. When the tube body 2 and the transferring cavity 33 are changed from the first connection state 24 to the second connection state 25, the cylindrical protrusion 311 pierces the breakable seal 22 at the bottom of the tube body 2, specifically, the thin-wall structure portion breaks, as shown in fig. 7, so that the diluent added with blood enters the filter element 32 through the hollow around the cylindrical protrusion 311. When the upper end surface of the connecting sleeve 3 contacts with the upper stop rib 26 of the pipe body 2, the erythrocyte is filtered on the filter element 32. In other embodiments, the acting protrusion 31 may include a cylindrical protrusion 311 with a tip, and a propping structure 312 that may be propped against the outer ring portion having a thin-walled structure, the propping structure 312 extending obliquely upward and outward from the sidewall of the cylindrical protrusion 311 to prop up the thin-walled structure, the cylindrical protrusion 311 to prop up the thick-walled structure, or the acting protrusion 31 may be just the propping structure 312 that is propped against the outer ring portion having a thin-walled structure, the propping structure 312 being obliquely upward from inside to outside to prop up the thin-walled structure. Of course, the frangible seal 22 may be a thin-wall sealing sheet with a thin-wall structure on the inner ring and the outer ring, the acting protrusion 31 may only have a pointed cylindrical protrusion 311 to jack up the thin-wall structure on the inner ring or/and the outer ring, or the frangible seal 22 may be a thin-wall structure on the inner ring and a thick-wall structure on the outer ring, and the pointed cylindrical protrusion 311 of the acting protrusion 31 jacks up the thin-wall structure on the inner ring, which is not limited in detail.

The use method of the utility model is that,

the initial state is divided into two parts:

the first part is a sampling tube 1, which is packed independently or matched with a tube body 2, a connecting sleeve 3 and a bearing tube 4;

the second part is a pipe body 2, a connecting sleeve 3 and a connecting pipe 4.

The sealing element 23 is fixed at the top of the pipe body 2, the liquid storage cavity 21 in the pipe body 2 contains a certain amount of diluent, the inner cavity of the connecting sleeve 3 is provided with a filter element 32, an action convex part 31 is arranged above the filter element 32, the bottom breakable seal 22 is in a closed state, the tip of a cylindrical bulge 311 or a supporting structure 312 (shown in fig. 7 and 8) which just contacts the action convex part 31 is semi-fixed (semi-fixed is semi-screwed/semi-buckled, a fixed state is achieved, and screwing/complete buckling can be continued until the upper end face of the connecting sleeve 3 is attached to the upper blocking rib 26) on the connecting sleeve 3. At this time, the pipe body 2 and the transfer cavity 33 are in the first connection state 24, as shown in fig. 4 and 5, i.e. the action protrusion 31 does not apply an external force to the frangible seal 22. Or the tube body 2 is individually packaged.

Step one: collecting a blood sample using the sampling tube 1;

step two: after collecting a blood sample, puncturing a sealing piece 23 on the upper side of the tube body 2 by utilizing a capillary tube 11 or a puncturing boss 12 on the sampling tube 1, immersing the capillary tube 11 at the bottom of the sampling tube 1 in a diluent in a liquid storage cavity 21 of the tube body 2, extruding the sampling tube, uniformly mixing blood and the diluent, and completing the dissolution and dilution of a blood sample;

step three: the pipe body 2 and the connecting sleeve 3 are further fixed (by screwing/buckling and other mechanical modes) until the upper end face of the connecting sleeve 3 is in contact with the upper baffle rib 26 of the pipe body 2, so that the action convex part 31 in the connecting sleeve 3 pierces the breakable seal 22 of the pipe body 2, or the supporting structure 312 on the connecting sleeve 3 jacks up the thinner part of the breakable seal 22 on the pipe body 2, so that the breakable seal 22 is broken to form a notch or partially or completely tilted, the blood diluent flows onto the filter piece 32 of the connecting sleeve 3, red blood cells are filtered on the filter piece 32, and the serum diluent flows into the receiving pipe 4 within 3 min.

Step four: the external force is applied to squeeze the adapter tube 4 or break the dent or unscrew the cap, and the sample is dripped on the test paper through the liquid outlet 41 for testing.

Example two

As shown in fig. 10 to 14, a sample separating device for detection comprises a sampling tube 1 for quantitatively sucking a sample, a tube body 2 having a hollow interior, a connecting sleeve 3, and a receiving tube 4 with a test strip connected to the lower portion of the connecting sleeve 3.

The structures of the sampling tube 1, the tube body 2 and the connecting sleeve 3 are the same as those of the first embodiment, and will not be described again. In this embodiment, the adapter tube 4 is connected to the lower part of the adapter sleeve 3, and is provided with a test strip 51 and a collection chamber 52 disposed near the lower end of the test strip 51. The bottom of the tube body 2 can be connected with the transfer cavity 33, the action protrusion 31 can open the breakable seal 22, and the liquid in the liquid storage cavity 21 flows to the collection cavity 52 after passing through the filter element 32 and reacts with the test strip 51.

The inside of the adapter tube 4 is provided with a clamping groove 53, part of the top of the clamping groove 53 is open, part of the opening is not contacted with the filter element 32, the bottom of the clamping groove is provided with a hollow, and the serum diluent performs chromatographic reaction through a hollow contact test strip 51 at the bottom of the clamping groove 53; or the clamping groove 53 is of a fully-closed structure except the bottom, the bottom of the clamping groove 53 is a movable half-open opening which can be opened and closed, a test strip can be put in the opening, and a certain gap is reserved after the opening, so that serum diluent contacts the test strip 51; or the test strip 51 is filled in the clamping groove in the production process, and a gap for entering the blood serum diluent is formed in the bottom of the clamping groove 53.

Specifically, the adaptor 4 is generally cylindrical or cone-shaped, and has a smaller volume, the collection chamber 52 is connected to the bottom of the adaptor 4, and is detachably connected or integrally connected (detachably connected, the test strip 51 is placed from a movable half-opening at the bottom of the adaptor 4, and integrally connected, the test strip 51 is placed from a top opening of the adaptor 4), so that the test strip 51 is conveniently placed in the adaptor 4 during production, and the detection result is displayed when the liquid level touches the bottom end of the test strip 51 and is chromatographically entered into the detection area of the test strip 51.

The use method of the utility model is that,

the initial state is divided into two parts:

the first part is a sampling tube 1, which is packed independently or matched with a tube body 2, a connecting sleeve 3 and a bearing tube 4;

the second part is the pipe body 2, the connecting sleeve 3, the connecting pipe 4 and the collecting cavity 52.

The sealing element 23 is fixed at the top of the pipe body 2, the liquid storage cavity 21 in the pipe body 2 contains a certain amount of diluent, the inner cavity of the connecting sleeve 3 is provided with a filter element 32, an action convex part 31 is arranged above the filter element 32, the bottom breakable seal 22 is in a closed state, the tip of a cylindrical bulge 311 or a supporting structure 312 (shown in fig. 7 and 8) which just contacts the action convex part 31 is semi-fixed (semi-fixed is semi-screwed/semi-buckled, a fixed state is achieved, and screwing/complete buckling can be continued until the upper end face of the connecting sleeve 3 is attached to the upper blocking rib 26) on the connecting sleeve 3. At this time, the pipe body 2 and the transfer cavity 33 are in the first connection state 24, that is, the action protrusion 31 does not apply an external force to the frangible seal 22. Or the tube body 2 is individually packaged.

Step one: collecting a blood sample using the sampling tube 1;

step two: after collecting a blood sample, puncturing a sealing piece 23 on the upper side of the tube body 2 by utilizing a capillary tube 11 or a puncturing boss 12 on the sampling tube 1, immersing the capillary tube 11 at the bottom of the sampling tube 1 in a diluent in a liquid storage cavity 21 of the tube body 2, extruding the sampling tube, uniformly mixing blood and the diluent, and completing the dissolution and dilution of a blood sample;

step three: the pipe body 2 and the connecting sleeve 3 are further fixed (by screwing/buckling and other mechanical modes) until the upper end face of the connecting sleeve 3 is in contact with the upper baffle rib 26 of the pipe body 2, the action convex part 31 in the connecting sleeve 3 pierces the breakable seal 22 of the pipe body 2, or the supporting structure 312 on the connecting sleeve 3 jacks up the thinner part of the breakable seal 22 on the pipe body 2, so that the thinner part is broken to form a notch or the breakable seal 22 is partially tilted or completely tilted, the blood diluent flows onto the filter piece 32 of the connecting sleeve 3, red blood cells are filtered on the filter piece 32, the serum diluent flows into the receiving pipe 4 to reach the collecting cavity 52 within 3min, the liquid level of the collecting cavity 52 contacts the bottom end of the test strip 51 and is chromatographically into the detection indication area of the test strip 51, and accordingly the detection result is displayed.

The following is a structure name and its corresponding information table.

The foregoing detailed description is provided to illustrate the present utility model and not to limit the utility model, and any modifications and changes made to the present utility model within the spirit of the present utility model and the scope of the appended claims fall within the scope of the present utility model.

Claims (10)

1. A sample separation apparatus for detection, comprising:

a sampling tube (1) for quantitatively sucking a sample;

the pipe body (2) is hollow and forms a liquid storage cavity (21) for containing diluent, the bottom of the pipe body is provided with a breakable seal (22), and the top opening of the pipe body is provided with a sealing piece (23);

a connecting sleeve (3) with an action convex part (31) inside, a filter element (32) arranged below the action convex part (31), and a switching cavity (33) formed at least on the periphery of the action convex part (31);

a connecting pipe (4) connected to the lower part of the connecting sleeve (3);

the bottom of the pipe body (2) can be connected with the switching cavity (33), and the action convex part (31) can open the breakable seal (22) so that the liquid in the liquid storage cavity (21) flows to the faucet pipe (4) after passing through the filter element (32).

2. The sample separation apparatus for detection according to claim 1, wherein: the inside of the connecting pipe (4) is provided with a test strip (51) and a collecting cavity (52) which is arranged near the lower end of the test strip (51), and the liquid in the liquid storage cavity (21) flows to the collecting cavity (52) after passing through the filter element (32) and reacts with the test strip (51).

3. The sample separation apparatus for detection according to claim 1, wherein: the adapter tube (4) is made of soft material, and the bottom of the adapter tube is provided with a liquid outlet hole (41).

4. A sample separation apparatus for detection according to claim 1 or 2 or 3, wherein: the bottom of the pipe body (2) and the switching cavity (33) are provided with a first connection state (24) and a second connection state (25), in the first connection state (24), the action protruding part (31) does not apply external force to the breakable seal (22), and in the second connection state (25), the action protruding part (31) upwards pushes the breakable seal (22).

5. The sample separation apparatus for detection according to claim 1, wherein: the sampling tube (1) has a capillary tube (11) and a piercing boss (12) for opening a seal (23); the seal (23) is an aluminum film.

6. The sample separation apparatus for detection according to claim 1, wherein: the bottom of the pipe body (2) is in threaded connection with the switching cavity (33), and an upper blocking rib (26) which can prop against the upper end face of the connecting sleeve (3) is arranged on the outer wall of the pipe body (2); or/and, the top of the connecting pipe (4) is in threaded connection with the lower part of the connecting sleeve (3), and the outer wall of the connecting pipe (4) is provided with a lower blocking rib (42) which can prop against the lower end face of the connecting sleeve (3).

7. The sample separation apparatus for detection according to claim 1, wherein: the filter element (32) is a filter element, an inner cavity (34) for clamping the filter element (32) is arranged in the connecting sleeve (3), and at least part of the end face of the connecting pipe (4) is propped against the lower surface of the filter element (32).

8. The sample separation apparatus for detection according to claim 1, wherein: the easy-to-crack seal (22) is a sealing piece, the outer ring part connected with the inner wall of the pipe body (2) is of a thin-wall structure, and the inner ring part is of a thick-wall structure; or the inner ring of the easy-to-crack sealing (22) is a thin-wall sealing piece.

9. The sample separation apparatus for detection according to claim 8, wherein: the action convex part (31) is a cylindrical convex part (311) with a tip, or/and the action convex part (31) is a supporting structure (312) which can be propped against the outer ring part.

10. The sample separation apparatus for detection according to claim 2, wherein: a clamping groove (53) for inserting the test strip (51) is formed in the side wall of the connecting pipe (4).