CN218271510U - Micro blood collection tube for blood coagulation detection and sample analyzer - Google Patents
Micro blood collection tube for blood coagulation detection and sample analyzer Download PDFInfo
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- CN218271510U CN218271510U CN202220383085.6U CN202220383085U CN218271510U CN 218271510 U CN218271510 U CN 218271510U CN 202220383085 U CN202220383085 U CN 202220383085U CN 218271510 U CN218271510 U CN 218271510U
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Abstract
The utility model discloses a trace heparin tube and sample analyzer for blood coagulation detects, trace heparin tube includes: an outer tube; an inner tube sleeved in the outer tube, wherein an anticoagulant is arranged in the inner tube, the value range of the length b' of the inner tube is more than or equal to 20mm and less than or equal to 40mm, and the volume range of the inner tube is more than or equal to 1ml and less than or equal to 2.5ml; the mouth of pipe of outer tube reaches the mouth of pipe of inner tube all with blood sampling tube stopper is connected. Above-mentioned trace heparin tube because the outside cover of inner tube is equipped with the outer tube, and the volume of drawing of trace blood can not lead to the fact the restriction to the size of outer tube, can set up the size of outer tube into conventional heparin tube to in with detecting instrument adaptation. The size of the inner tube is limited so as to be convenient for matching the internal trace blood, the influence on the subsequent sample sucking and extracting operation due to less trace blood in sampling is avoided, and the trace blood sampling and detection are facilitated.
Description
Technical Field
The utility model relates to a blood sampling equipment technical field, in particular to a trace heparin tube and sample analyzer for blood coagulation detects.
Background
The blood coagulation detection is a method for detecting a human blood coagulation system and a fibrinolysis system, judges whether relevant systems have problems or not, and is used for finding out the reasons of the problems and guiding clinical treatment.
In general, blood coagulation tests require 2ml or more of venous blood for testing, but in daily clinical tests, a minute amount or a small amount of blood may be required. For example, there are some situations in which it is desirable to perform a blood clotting test on an infant patient's blood sample. Under the general condition, the blood vessels of infants are fragile, and due to the pain and fear of the infants generated during puncture sampling, the infants are easy to generate the uncoordinated condition, the whole blood sampling detection process is very inconvenient, the blood sampling of more than 2ml is difficult, and the blood sampling of less than 2ml is generally acquired.
The conventional blood collection tube has a large size for adapting to a detection instrument, and a micro or small amount of blood collection mode is inconvenient for extracting and detecting a sample in the blood collection tube.
Therefore, how to facilitate the sampling and detection of trace blood is a problem to be solved urgently by those skilled in the art.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides a trace heparin tube for blood coagulation detects to make things convenient for trace blood sampling and detection. The utility model also provides a sample analyzer.
In order to achieve the above object, the utility model provides a following technical scheme:
a micro blood collection tube for blood coagulation detection, comprising:
an outer tube;
an inner tube sleeved in the outer tube, wherein an anticoagulant is arranged in the inner tube, the value range of the length b' of the inner tube is more than or equal to 20mm and less than or equal to 40mm, and the volume range of the inner tube is more than or equal to 1ml and less than or equal to 2.5ml;
the mouth of pipe of outer tube reaches the mouth of pipe of inner tube all with blood sampling tube stopper is connected.
The utility model also provides a sample analyzer, include:
a sampling tube mounting position for mounting a centrifuged blood collection tube, which may be a micro blood collection tube as described in any one of the above;
the sample sucking device is used for sucking and extracting a sample in the blood sampling tube, and a sample needle of the sample sucking device can extend into the inner tube of the micro blood sampling tube for sucking the sample;
and the analysis device is used for analyzing the sample extracted by the sample suction device.
According to the above technical scheme, the utility model provides a trace heparin tube sets up the structure of establishing to outer tube and inner tube cover each other through with trace heparin tube to the mouth of pipe that will adopt vascular stopper and outer tube and the mouth of pipe of inner tube are connected, form a holistic blood sampling tube structure. Because the inner tube is internally provided with the anticoagulant, in the process of blood sampling of trace amount, a sample enters the inner tube and is mixed with the anticoagulant. And because the outside cover of inner tube is equipped with the outer tube, the volume of drawing of trace blood can not lead to the fact the restriction to the size of outer tube, can set up the size of outer tube into conventional heparin tube to in with detecting instrument adaptation. The value range of the length b' of the inner tube is more than or equal to 20mm and less than or equal to 40mm, and the volume range of the inner tube is more than or equal to 1ml and less than or equal to 2.5ml, so that the size of the inner tube is limited to be convenient for matching with the trace blood in the inner tube, the influence on the subsequent sample sucking and extracting operation due to less trace blood in sampling is avoided, and the trace blood sampling and detection are convenient.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a first schematic structural view of a micro blood collection tube according to an embodiment of the present invention;
fig. 2 is a second schematic structural view of a micro blood collection tube according to an embodiment of the present invention;
fig. 3 is a third schematic structural view of the micro blood collection tube according to the embodiment of the present invention.
Detailed Description
The utility model discloses a trace heparin tube for blood coagulation detects to make things convenient for trace blood sampling and detection. The utility model also provides a sample analyzer.
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
As shown in fig. 1, the embodiment of the utility model provides a micro blood sampling tube for blood coagulation detection, including outer tube 1, inner tube 2 and blood sampling tube stopper 3, wherein, inner tube 2 cover is located in outer tube 1, has the anticoagulant in inner tube 2, and the value range of length b 'of inner tube 2 is that 20mm is no less than b' is no more than 40mm, and the volume range of inner tube 2 is that 1ml is no less than L is no less than 2.5ml; the mouth of pipe of outer tube 1 and the mouth of pipe of inner tube 2 all are connected with heparin tube stopper 3.
The embodiment of the utility model provides a trace heparin tube sets up the structure of establishing into outer tube 1 and inner tube 2 mutual cover through setting up trace heparin tube to be connected heparin tube stopper 3 and the mouth of pipe of outer tube 1 and the mouth of pipe of inner tube 2, form a holistic blood sampling tube structure. Because the inner tube 2 contains an anticoagulant, during a trace blood collection procedure, the sample enters the inner tube 2 and mixes with the anticoagulant. And because the outside cover of inner tube 2 is equipped with outer tube 1, the volume of drawing of trace blood can not lead to the fact the restriction to the size of outer tube 1, can set up the size of outer tube 1 into conventional heparin tube to in with detecting instrument adaptation. The value range of the length b' of the inner tube 2 is more than or equal to 20mm and less than or equal to 40mm, and the volume range of the inner tube is more than or equal to 1ml and less than or equal to 2.5ml, so that the size of the inner tube 2 is limited to be convenient for matching the micro blood in the inner tube, the influence on the subsequent sample sucking and extracting operation due to less micro blood is avoided, and the sampling and the detection of the micro blood are convenient.
In the blood coagulation detection, before the sample is sucked by the sample needle, the blood sample in the micro blood collecting tube needs to be centrifugally separated, the blood sample after centrifugal separation is divided into an upper layer and a lower layer in the inner tube 2 of the micro blood collecting tube, the lower layer is a blood cell layer, the blood sample in the upper layer above the blood cell layer is generally defined as a sample dead volume, and if the sample needle is too close to the blood cell layer (the lower layer) during sample suction, the blood cell is sucked, so that the condition that the needle blockage failure or the test result is abnormal is caused. In order to ensure the operation of sucking the upper blood sample by the sample needle and reduce the risk of sucking blood cells, the sample needle needs to be at least a certain distance (usually 3-4 mm) away from the blood cell layer when sucking the sample, which requires that the upper blood sample has at least a certain liquid level height (about 3-4 mm). In this embodiment, the volume range of the inner tube 2 is 1ml or more and L or less and 2.5ml or less, and the length b 'of the inner tube 2 is 20mm or more and b' or less and 40mm or less, so that the inner diameter of the inner tube 2 is small (compared with the conventional blood collection tube and the outer tube 1), which ensures that the upper blood sample (dead volume of the sample) has sufficient liquid level height, and facilitates the sample suction end of the sample needle to be positioned in the upper blood sample for sucking the blood sample, so as to reduce the risk of sucking blood cells. Through the arrangement, the sample suction and extraction operation is ensured, and the normal operation of subsequent tests is also ensured.
In order to ensure the subsequent operation of the blood sample in the micro blood collection tube, the predicted blood collection amount L' of the micro blood collection tube is less than or equal to 1ml; that is, after the sampling is completed, a space is reserved in the inner tube 2 for a subsequent operation (e.g., centrifugal separation). Wherein, the ratio of the capacity C of the anticoagulant to the estimated blood collection amount L' in the inner tube 2 has a value range of 1. To ensure an anticoagulant effect.
As shown in fig. 1, in the first embodiment, the inner tube 2 is a cylindrical tube, one end of the inner tube 2 is connected to the blood collection tube stopper 3, and the other end of the inner tube 2 is a tube bottom surface. Wherein, the tube bottom surface of the inner tube 2 is a hemisphere bottom surface. That is, the inner pipe 2 may be similar to the outer pipe 1 in structure, so as to facilitate the adjustment of the inner diameter of the inner pipe 2 according to the length b' requirement of the inner pipe 2.
Preferably, the inner diameter a 'of the inner tube 2 is in the range of 7 mm. Ltoreq. A' 9mm.
In order to have a uniform gap between the outer periphery of the inner tube 2 and the inner periphery of the outer tube 1, it is preferable to overlap the axes of the inner tube 2 and the outer tube 1.
As shown in fig. 2, in the second embodiment, the inner tube 2 is a cylindrical tube, one end of the inner tube 2 is connected to the blood collection tube stopper 3, and the other end of the inner tube 2 is a tube bottom surface. Wherein, the bottom surface of the inner tube 2 is a conical bottom surface. Through the above operation, the height of the inner tube 2 is lengthened as much as possible, and the probability that the sampling needle contacts the bottom surface of the inner tube 2 is also reduced.
Preferably, the inner diameter a 'of the inner tube 2 preferably ranges from 7 mm. Ltoreq. A'. Ltoreq.9 mm.
In order to have a uniform gap between the outer periphery of the inner tube 2 and the inner periphery of the outer tube 1, it is preferable to overlap the axes of the inner tube 2 and the outer tube 1.
As shown in fig. 3, in the third embodiment, the inner tube 2 is a tapered tube, the large end of the inner tube 2 is connected to the blood collection tube stopper 3, and the other end of the inner tube 2 is a tube bottom surface. Wherein, the toper body can be conical body, also can be the pyramid body. The cross-sectional area of the large end of the inner tube 2 is larger than the cross-sectional area of the small end of the inner tube 2. Wherein, the bottom surface of the inner tube 2 is a conical bottom surface. In this embodiment, the taper of the bottom surface of the inner tube 2 is larger than the taper of the tube body (tapered tube body) of the inner tube 2. Of course, the taper of the bottom surface of the inner pipe 2 may be made smaller than or equal to the taper of the pipe body (tapered pipe body) of the inner pipe 2.
Of course, the inner tube 2 may be a conical tube, and the bottom surface of the inner tube 2 may be a hemispherical bottom surface. Or, the inner tube 2 is set to be a cylindrical tube body or a conical tube body, the bottom surface of the inner tube 2 is flat, and the flat bottom is perpendicular to the axis of the inner tube 2 or forms a certain included angle with the axis of the inner tube 2. Are not particularly limited and are within the scope of protection.
In order to realize the flow of the blood sample into the inner tube 2, the inner tube 2 is in a vacuum state. The inner tube 2 may be filled with a certain amount of gas (gas that does not affect the blood sample) so that the inner tube 2 is in a negative pressure state.
Further, the cavity between the inner tube 2 and the outer tube 1 is in a vacuum state.
In order to ensure that the micro blood collection tube is matched with the detection instrument as much as possible, the value range of the tube body diameter a of the outer tube 1 is more than or equal to 12mm and less than or equal to 13mm; the length b of the outer tube 1 is more than or equal to 58mm; the value range of the diameter d of the blood collecting plug 3 is that d is more than or equal to a +1mm and less than or equal to 18mm; the value range of the overall length c of the micro blood collection tube is that c is more than or equal to 80mm and less than or equal to 83mm.
In the present embodiment, the axis of the outer tube 1 coincides with the axis of the inner tube 2. Through the arrangement, the micro blood collection tube is centrosymmetric, and subsequent operations (such as centrifugal separation and the like) are facilitated.
The embodiment of the utility model provides a still provide a sample analyzer, include sampling pipe installation position, inhale appearance device and analytical equipment. The sampling tube mounting position is used for mounting a blood collection tube after centrifugal separation, and the blood collection tube can be any one of the micro blood collection tubes; the sample sucking device is used for sucking and extracting a sample in the blood sampling tube, and a sample needle of the sample sucking device can extend into the inner tube 2 of the micro blood sampling tube to suck the sample; the analysis device is used for analyzing the sample extracted by the sample suction device.
The embodiment of the utility model provides a sample analyzer can install above-mentioned trace heparin tube in sample analyzer's sampling pipe installation position and detect, consequently, has made things convenient for trace blood sampling and detection.
Preferably, the sample suction device is provided with a liquid level detection unit, and the liquid level detection unit is used for detecting the liquid level in the blood sampling tube; the liquid level detection unit is in communication connection with a driving device for controlling the sample needle to operate by the sample sucking device;
when the liquid level detection unit detects that the sample needle reaches the liquid level in the blood sampling tube or is a preset distance away from the liquid level in the blood sampling tube, the driving device drives the sample needle to operate in a speed reduction mode.
The liquid level detection technology is usually adopted in the sample sucking process of the sample needle, the sample needle is controlled by a driving structure and probes at a certain speed, and when the sample needle detects the liquid level, the speed is reduced and stopped. In the process of deceleration and stop of the sample needle, the sample needle can also downwards probe to a certain depth, in order to avoid puncturing a blood cell layer (lower layer), in the process of liquid level detection, the liquid level detection unit drives the sample needle to adopt a curve of first acceleration and then uniform motion in the previous stroke, when the liquid level is close to the liquid level with the expected sample height, the driving device drives the sample needle to perform deceleration motion, and liquid level detection is performed at a lower speed, so that the overshoot depth of downward probe of the sample needle in the process of liquid level detection is effectively controlled, and the influence on the volume height of a sample volume is effectively reduced.
Further, the sample analyzer has a trace blood detection mode and a regular blood detection mode. Sample analyzers typically require that the amount of sample (blood sample) needed for analysis be predetermined and that more than the required amount be collected from a sample provider for routine blood testing. However, when the sample provider is an infant, a young child, or a critically ill patient, it is difficult to collect the sample in the required amount, and therefore, it is possible to collect only a trace amount of sample and a sample prepared by combining a reagent such as a diluent for the purpose of trace blood detection. In this embodiment, the trace blood detection mode of the sample analyzer is to perform sample analysis on a sample prepared by collecting a trace amount of sample in combination with a reagent such as a diluent.
In a micro blood detection mode, the sampling tube mounting position is provided with any one of the micro blood collection tubes; under the conventional blood test mode, the sampling pipe installation position installs conventional heparin tube. Through the arrangement, the detection range of the sample analyzer is effectively enlarged, and the universality of the sample analyzer is improved.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. A micro blood collection tube for blood coagulation detection, comprising:
an outer tube (1);
the anticoagulant catheter comprises an inner tube (2) sleeved in the outer tube (1), wherein an anticoagulant is arranged in the inner tube (2), the value range of the length b' of the inner tube (2) is more than or equal to 20mm and less than or equal to 40mm, and the volume range of the inner tube (2) is more than or equal to 1ml and less than or equal to 2.5ml;
the orifice of the outer tube (1) and the orifice of the inner tube (2) are both connected with the blood collection plug (3); one end of the inner tube (2) is connected with the blood sampling plug (3), and the other end of the inner tube (2) is a tube bottom surface.
2. The micro blood collection tube of claim 1, wherein the expected blood collection volume of the micro blood collection tube is L' is less than or equal to 1ml;
the ratio of the volume C of the anticoagulant to the expected blood collection volume L' in the inner tube (2) ranges from 1.
3. The micro blood collection tube according to claim 1, wherein the inner tube (2) is a cylindrical tube body, one end of the inner tube (2) is connected to the blood collection plug (3), and the other end of the inner tube (2) is a tube bottom surface.
4. The micro blood collection tube according to claim 3, wherein the inner diameter a 'of the inner tube (2) is in a range of 7 mm. Ltoreq. A' to 9mm.
5. The micro blood collection tube according to claim 1, wherein the inner tube (2) is a tapered tube, a large end of the inner tube (2) is connected to the blood collection plug (3), and the other end of the inner tube (2) is a tube bottom surface.
6. The micro blood collection tube according to any one of claims 3 to 5, wherein the bottom surface of the inner tube (2) is a hemispherical bottom surface or a conical bottom surface.
7. The micro blood collection tube according to claim 1, wherein the inside of the inner tube (2) is in a vacuum state.
8. The micro blood collection tube according to claim 7, wherein a cavity between the inner tube (2) and the outer tube (1) is in a vacuum state.
9. The micro blood collection tube according to claim 1, wherein the diameter a of the outer tube (1) is in a range of 12mm ≦ a ≦ 13mm;
the length b of the outer tube (1) is more than or equal to 58mm;
the value range of the diameter d of the blood collection plug (3) is that d is more than or equal to a +1mm and less than or equal to 18mm;
the value range of the whole length c of the micro blood collection tube is that c is more than or equal to 80mm and less than or equal to 83mm.
10. The micropixel according to claim 1, characterized in that the axis of the outer tube (1) coincides with the axis of the inner tube (2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220383085.6U CN218271510U (en) | 2022-02-23 | 2022-02-23 | Micro blood collection tube for blood coagulation detection and sample analyzer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220383085.6U CN218271510U (en) | 2022-02-23 | 2022-02-23 | Micro blood collection tube for blood coagulation detection and sample analyzer |
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| Publication Number | Publication Date |
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| CN218271510U true CN218271510U (en) | 2023-01-10 |
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| CN202220383085.6U Active CN218271510U (en) | 2022-02-23 | 2022-02-23 | Micro blood collection tube for blood coagulation detection and sample analyzer |
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| CN (1) | CN218271510U (en) |
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