CN219391366U

CN219391366U - Closed excrement filtering and sampling device

Info

Publication number: CN219391366U
Application number: CN202223134628.XU
Authority: CN
Inventors: 严国志; 余昕; 董兰兰; 周谛晗; 张良禄
Original assignee: Wuhan Aimisen Life Technology Co ltd
Current assignee: Wuhan Aimisen Life Technology Co ltd
Priority date: 2022-11-24
Filing date: 2022-11-24
Publication date: 2023-07-21
Anticipated expiration: 2032-11-24

Abstract

The utility model discloses a closed fecal filtering and sampling device, which belongs to the technical field of medical instruments and comprises a sampling tube, wherein a containing cavity is arranged in the sampling tube, an opening is arranged at the upper end of the sampling tube, a hollow filter tube is detachably arranged in the containing cavity, the filter tube separates the containing cavity into an impurity cavity and a filtrate cavity, a first sealing cover which is matched with the opening and is used for sealing the impurity cavity is arranged at the upper end of the filter tube, a liquid taking opening which is communicated with the filtrate cavity is arranged in the middle of the first sealing cover, and a second sealing cover which is used for sealing the filtrate cavity is detachably arranged above the first sealing cover. The closed fecal filtering and sampling device has the advantages of simple structure, lower cost, portability and convenient use, and simplifies the sampling steps.

Description

Closed excrement filtering and sampling device

Technical Field

The utility model belongs to the technical field of medical instruments, and particularly relates to a closed fecal filtering and sampling device.

Background

In the prior art, detection of colorectal diseases such as colorectal cancer is an effective means by detecting the faeces of patients. The existing fecal sample sampling is to take a proper amount of sample, put the sample into a sampling container with fecal DNA preservation liquid, and extract and detect supernatant with few impurities before detection. Therefore, in the case of treating a fecal sample, solid-liquid separation is required.

The existing separation method of the supernatant liquid of the fecal sample and the fecal residue and impurities is mainly to separate by a centrifugal machine. However, the centrifuge has large volume, certain requirements on environment and space, is limited by the field when in use, is inconvenient to carry, and has higher cost. In addition, fecal samples often have a certain odor, a poor sensory experience, and are prone to psychological interference by the operator. And during centrifugal operation, samples in the centrifugal machine are required to be balanced, and the original samples are required to be subjected to decrement treatment, so that psychological burden and operation difficulty of operators are increased. Therefore, there is a need for a fecal sample solid-liquid separation device that reduces the number of handling steps and is easy to handle.

Disclosure of Invention

Aiming at the defects of the prior art, the utility model aims to provide a closed type fecal filtering and sampling device, which aims to solve the problems that a centrifuge is limited by a field, is inconvenient to carry and has complex operation steps in the process of extracting fecal samples in the prior art.

In order to achieve the above purpose, the utility model provides a closed fecal filtering and sampling device, which comprises a sampling tube, wherein a containing cavity is arranged in the sampling tube, an opening is arranged at the upper end of the sampling tube, a hollow filter tube is detachably arranged in the containing cavity, the filter tube separates the containing cavity into an impurity cavity and a filtrate cavity, a first sealing cover which is matched with the opening and is used for sealing the impurity cavity is arranged at the upper end of the filter tube, a liquid taking opening which is communicated with the filtrate cavity is arranged in the middle of the first sealing cover, and a second sealing cover which is used for sealing the filtrate cavity is detachably arranged above the first sealing cover.

Still further, the filter tube includes less than or equal to three layers of filter screens.

Still further, the filter tube includes outer filter screen, inlayer filter screen that outside to interior coaxial setting in proper order, the filtration pore aperture of outer filter screen is greater than the filtration pore aperture of inlayer filter screen.

Still further, still be equipped with the middle level filter screen between outer filter screen, the inlayer filter screen, the filtration pore aperture of middle level filter screen is less than the filtration pore aperture of outer filter screen and be greater than the filtration pore aperture of inlayer filter screen.

Further, the pore size of the filter pores of the outer layer filter screen is 70-150 mu m, and the pore size of the filter pores of the inner layer filter screen is 20-50 mu m.

Further, the first sealing cover and the opening are sealed through threaded connection, and the second sealing cover is used for sealing the liquid taking port through threaded connection.

Furthermore, a sampling spoon is arranged at the bottom of the filter tube.

Further, the pipe diameter of the filter pipe is smaller than that of the sampling pipe, and the pipe diameter of the filter pipe is 1/3-1/2 of that of the sampling pipe.

Furthermore, the outer wall of the sampling tube is uniformly provided with scales from top to bottom in sequence, the scales are provided with maximum values and minimum values, and the lower end face of the filter tube is positioned below the minimum values of the scales.

Furthermore, the filter screen is a polyamide fiber integrated filter screen, and the filter screen is provided with reinforcing connecting ribs.

The technical proposal which is conceived by the utility model has the following compared with the prior art

The beneficial effects are that:

(1) Due to the fact that the filter tube and the sampling tube are arranged, a centrifugal machine is not needed, solid-liquid separation can be directly carried out on a detection sample in the sampling tube only by vibration, time and space are saved, the device is convenient to use, is not limited by laboratory equipment and sites, is simple in structure, is low in cost, and is convenient to carry.

(2) The filter tube can be composed of a plurality of layers of filter screens, components contained in the filtered liquid can be controlled by controlling the number of layers of the filter screens and the pore size of the filter screen pore diameter, so that the impurity removal rate is improved, and the detection accuracy of a sample is improved.

(3) The whole device is completely sealed when the detection sample is subjected to solid-liquid separation, balancing operation is not needed, the operation steps of operators can be reduced, and the sensory feeling of the operators in the detection process is improved.

(4) The bottom of the filter tube is also provided with a sampling spoon, so that an independent sampling spoon is not required, a sampling structure is simplified, and the sampling cost is saved.

Drawings

FIG. 1 is an exploded view of a closed fecal filtration sampling device according to the present utility model;

FIG. 2 is a schematic diagram of a closed fecal filtering and sampling device according to the present utility model;

FIG. 3 is a cross-sectional view of a closed fecal filtration sampling device provided by the present utility model;

fig. 4 is a schematic structural view of a filter tube of the closed fecal filtering and sampling device provided by the utility model.

The corresponding structure of each numerical mark in the attached drawings is as follows: 1-sampling tube, 11-opening, 12-impurity cavity, 13-filtrate cavity, 14-scale, 2-filter tube, 21-outer filter screen, 22-inner filter screen, 3-first sealing cover, 31-liquid taking port, 4-second sealing cover, 5-sampling spoon and 6-reinforcing connecting rib.

Detailed Description

The present utility model will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present utility model more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the utility model.

The utility model will be further described with reference to specific drawings and examples.

Example 1

Referring to FIGS. 1 to ² The utility model provides a closed fecal filtering and sampling device, which specifically comprises a sampling tube 1, wherein a containing cavity is arranged in the sampling tube 1, an opening 11 is arranged at the upper end of the sampling tube, a filter tube 2 with a hollow inside is detachably arranged in the containing cavity, the containing cavity is divided into an impurity cavity 12 and a filtrate cavity 13 by the filter tube 2, a first sealing cover 3 which is matched with the opening 11 and is used for sealing the impurity cavity 12 is arranged at the upper end of the filter tube 2, a liquid taking port 31 which is communicated with the filtrate cavity 13 is arranged in the middle of the first sealing cover 3, and a second sealing cover 4 which is used for sealing the filtrate cavity 13 is detachably arranged above the first sealing cover 3; the pipe diameter of the filter pipe 2 is smaller than that of the sampling pipe 1, and specifically, the pipe diameter of the filter pipe 2 is 1/3-1/2 of that of the sampling pipe 1.

When in use, the fecal preservation solution is added into the sampling tube 1, and then the fecal sample is added into the sampling tube 1, so that the fecal sample is mixed with the preservation solution. And then the filter tube 2 is put into the sampling tube, the sampling tube 1 is sealed by adopting the first sealing cover 3, and the second sealing cover 4 is tightly covered. And (3) shaking or vibrating the device, so that part of sample liquid enters the filtrate cavity 13 through the filter holes on the filter tube, and impurities which cannot penetrate the filter screen are trapped in the impurity cavity 13, thereby realizing solid-liquid separation. The laboratory staff can take out the filtrate in the filter tube from the liquid taking port 31 by using a liquid-transferring gun or a liquid-taking device, or can open the second sealing cover 4 without opening the first sealing cover 3 to pour out the filtered liquid from the liquid taking port 31.

Example 2

As shown in fig. 1 and 2, this embodiment is a further improvement on the basis of embodiment 1, and is specifically as follows:

in order to improve the detection effect, impurities are further separated, on the basis of embodiment 1, one layer of filter screen is difficult to effectively separate impurities, liquid penetrating through the filter screen under the action of too much resistance oscillation of the layer number is limited, enough filtrate is difficult to collect, the filter tube 2 is composed of filter screens smaller than or equal to three layers, in this embodiment, only two layers of filter screens are adopted, as shown in fig. 3, the filter tube 2 comprises an outer layer filter screen 21 and an inner layer filter screen 22 which are coaxially arranged in sequence from outside to inside, and the pore diameter of the filter hole of the outer layer filter screen is larger than that of the inner layer filter screen, so as to improve the structural strength of the filter screen, as shown in fig. 4, a reinforcing connecting rib 6 is arranged on the filter screen.

In order to further improve the filtering effect, in some embodiments, a middle layer filter screen is further arranged between the outer layer filter screen and the inner layer filter screen, and the pore diameter of the middle layer filter screen is smaller than that of the outer layer filter screen and larger than that of the inner layer filter screen. Furthermore, the filter screen is a polyimide fiber (nylon) integrated filter screen.

The pore size of the outer layer filter screen is 70-150 μm, the pore size of the inner layer filter screen is 20-50 μm, if the middle layer filter screen is present, the pore size of the middle layer filter screen is 50-70 μm. The aperture arrangement can effectively separate fecal sample impurities, and separate cfDNA (abbreviation of cell free DNA, which refers to highly fragmented DNA which exists in human blood circulation and is free from cells) into filtrate under specific conditions (such as tumor patients, pregnant women, patients receiving organ transplantation, and the like) as much as possible, so that the sample requirement of gene methylation detection can be met.

Example 3

As shown in fig. 2, this embodiment is a further improvement on the basis of embodiment 2, and is specifically as follows:

in order to facilitate the disassembly between the first sealing cover 3 and the opening 11, and between the first sealing cover 4 and the second sealing cover 4, in this example, the first sealing cover 3 and the opening 11, and the second sealing cover 4 are all connected through threads, specifically, as shown in fig. 2, the outer wall of the opening 11 is provided with external threads, and the inner wall of the lower end of the first sealing cover 3 is provided with internal threads matched with the opening 11. Similarly, the cover surface of the first sealing cover 3 extends upwards in the axial direction to form an upper end portion, the upper end portion is provided with external threads, and the lower end portion of the second sealing cover 4 is provided with internal threads matched with the external threads.

The first sealing cover 3 is arranged at the upper end of the filter tube 2, and further, the first sealing cover 3 and the filter tube 2 are formed in two ways, one is split type, namely, the first sealing cover 3 and the filter tube 2 are formed separately and are connected through threads, and the other is integrated, namely, the first sealing cover 3 and the filter tube 2 are formed integrally.

Further, in order to improve the tightness of the first seal 3 and the second seal cover 4, in some embodiments, sealing gaskets may be attached to inner end surfaces of the first seal cover 3 and the second seal cover 4, so as to avoid liquid overflowing during vibration or shaking of the device.

Example 4

As shown in fig. 1 and 2, this embodiment is a further improvement on the basis of embodiment 2 or 3, and is specifically as follows:

in order to further simplify the sampling structure, the bottom of the filter tube 2 is also provided with a sampling spoon 5, the first sealing cover 3 is fixedly connected with the filter tube 2, the first sealing cover 3 can be directly used as a handheld part, the sampling spoon 5 is used for sampling and then is placed into a sampling tube, the first sealing cover and the second sealing cover are directly screwed, sampling is completed, and anti-slip grooves are uniformly distributed on the side walls of the first sealing cover and the second sealing cover for increasing the friction force during screwing. Realize the integration of whole sampling subassembly, simplify the structure of sampling subassembly, no longer need set up the sample spoon alone.

Example 5

As shown in fig. 1 and 2, this embodiment is a further improvement on the basis of embodiment 2, 3 or 4, and is specifically as follows:

in order to observe and control the amount of filtrate, the sampling tube can be a 20-50ml centrifuge tube or other reagent tubes in other shapes, which are transparent tubes, so long as the preservation of the liquid sample can be realized and the sampling tube can be matched with the filter tube. In some embodiments, the sampling tube may be a flat-bottomed cylindrical sampling tube, which is convenient to place.

Further, in order to achieve accurate measurement of filtrate, scales are sequentially and uniformly distributed on the outer wall of the sampling tube 1 from top to bottom, the scales are provided with maximum values and minimum values, the lower end face of the filter tube 2 is located below the minimum values of the scales, and when standing is ensured, the filtrate can be reserved in the filter tube 2.

It will be readily appreciated by those skilled in the art that the foregoing description is merely a preferred embodiment of the utility model and is not intended to limit the utility model, but any modifications, equivalents, improvements or alternatives falling within the spirit and principles of the utility model are intended to be included within the scope of the utility model.

Claims

1. Closed excrement and urine filters sampling device, its characterized in that: including sampling tube (1), sampling tube (1) inside is equipped with holds chamber and upper end and is equipped with opening (11), hold intracavity detachable and be equipped with inside hollow filter tube (2), filter tube (2) will hold the chamber and separate into impurity chamber (12) and filtrating chamber (13), filter tube (2) upper end be equipped with be used for with opening (11) cooperation is used for sealedly first sealed lid (3) of impurity chamber (12), be equipped with in the middle of first sealed lid (3) with liquid taking mouth (31) of filtrating chamber (13) intercommunication, first sealed lid (3) top detachable be equipped with be used for sealing second sealed lid (4) of filtrating chamber (13).

2. The sealed fecal filtration sampling device according to claim 1, wherein: the filter pipe (2) comprises a filter screen with three layers or less.

3. The sealed fecal filtration sampling device according to claim 2, wherein: the filter tube (2) comprises an outer filter screen and an inner filter screen which are coaxially arranged in sequence from outside to inside, and the aperture of the filter hole of the outer filter screen is larger than that of the filter hole of the inner filter screen.

4. A closed stool filtering and sampling apparatus according to claim 3, wherein: and a middle filter screen is further arranged between the outer filter screen and the inner filter screen, and the aperture of the filter hole of the middle filter screen is smaller than that of the outer filter screen and larger than that of the inner filter screen.

5. The sealed fecal filtration sampling device according to claim 4, wherein: the pore size of the filter holes of the outer layer filter screen is 70-150 mu m, and the pore size of the filter holes of the inner layer filter screen is 20-50 mu m.

6. The sealed fecal filtration sampling device according to claim 1, wherein: the first sealing cover (3) and the opening (11) are sealed through threaded connection, and the second sealing cover (4) and the first sealing cover (3) are sealed through threaded connection and the liquid taking opening (31).

7. The sealed fecal filtration sampling device according to claim 1, wherein: the bottom of the filter tube (2) is also provided with a sampling spoon (5).

8. The sealed fecal filtration sampling device according to claim 1, wherein: the pipe diameter of the filter pipe (2) is smaller than that of the sampling pipe (1), and the pipe diameter of the filter pipe (2) is 1/3-1/2 of that of the sampling pipe (1).

9. The sealed fecal filtration sampling device according to claim 1, wherein: the outer wall of the sampling tube (1) is uniformly provided with scales from top to bottom in sequence, the scales are provided with maximum values and minimum values, and the lower end face of the filter tube (2) is positioned below the minimum values of the scales.

10. The sealed fecal filtration sampling device according to claim 2, wherein: the filter screen is a polyamide fiber integrated filter screen, and the filter screen is provided with reinforcing connecting ribs (6).