CN219273115U - 96-hole plate sample adding anti-pollution device - Google Patents
96-hole plate sample adding anti-pollution device Download PDFInfo
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- CN219273115U CN219273115U CN202321288419.2U CN202321288419U CN219273115U CN 219273115 U CN219273115 U CN 219273115U CN 202321288419 U CN202321288419 U CN 202321288419U CN 219273115 U CN219273115 U CN 219273115U
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E30/00—Energy generation of nuclear origin
- Y02E30/30—Nuclear fission reactors
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Abstract
The utility model relates to a 96-well plate sample adding anti-pollution device, which comprises: the base is used for placing and fixing the 96-well plate body; the anti-pollution structure is used for preventing the sample from being added with wrong holes and protecting other samples in the holes from being cross-polluted by aerosol when the single-hole sample is added, so that the accuracy of the experiment is improved; the base is internally provided with a 96-hole plate body, the anti-pollution structure is arranged at the upper part of the 96-hole plate and is detachably connected with the base; the anti-pollution structure comprises a bottom plate, a cover plate and a shielding sheet; the bottom plate is fixedly connected with the cover plate, the shielding sheets are arranged between the bottom plate and the cover plate and can slide between the bottom plate and the cover plate, the shielding sheets are square, and each shielding sheet shields one hole site; during sample addition, the shielding plate covers other holes around the sample addition hole, so that accurate shielding of the hole site after sample addition is ensured, and only the upper part of the next pre-sample addition hole site is empty, so that cross contamination is avoided, and the operation is simple.
Description
Technical Field
The utility model belongs to the technical field of medical instruments, and particularly relates to a 96-well plate sample adding anti-pollution device.
Background
The 96-well plate is a commonly used reaction container, is widely used in the fields of clinical diagnosis, biological research and the like of hospitals or scientific research laboratories, and realizes high-throughput operations on biological samples, such as protein precipitation, cell and human body fluid extraction, nucleic acid extraction and the like by using a combined gang gun, high-throughput automatic liquid operation instrument and software, so that the efficiency of sample processing is greatly improved, but due to the high cost of automatic sample adding equipment, part of hospitals or scientific research laboratories still adopt a manual sample adding method for operation.
It is widely applied in the fields of clinical diagnosis, biological research and the like in hospitals or scientific research laboratories. 96. When the pore plate is used for loading samples, all the sample loading holes are in a leakage state, sampling errors or splashing can easily occur, and when samples are splashed, cross contamination occurs among the sample loading holes due to the existence of aerosol, so that experimental results are influenced.
The utility model aims at the problems and provides a 96-well plate sample adding and pollution preventing device.
Disclosure of Invention
In order to overcome the problems in the background art, the utility model adopts the following technical scheme:
a 96-well plate loading contamination prevention device, comprising:
the base is used for placing and fixing the 96-well plate body;
the anti-pollution structure is used for preventing the sample from being added with wrong holes and protecting other samples in the holes from being cross-polluted by aerosol when the single-hole sample is added, so that the accuracy of the experiment is improved; the base is internally provided with a 96-hole plate body, the anti-pollution structure is arranged at the upper part of the 96-hole plate and is detachably connected with the base; the anti-pollution structure comprises a bottom plate, a cover plate and a shielding sheet; the bottom plate is fixedly connected with the cover plate, the shielding sheets are arranged between the bottom plate and the cover plate and can slide between the bottom plate and the cover plate, the shielding sheets are square, and each shielding sheet shields one hole site; during sample addition, the shielding plate covers other holes around the sample addition hole, so that accurate shielding of the hole site after sample addition is ensured, and only the upper part of the next pre-sample addition hole site is empty, so that cross contamination is avoided, and the operation is simple.
Further, a first groove is formed in the upper portion of the base, and the length and the width of the first groove are greater than or equal to those of the 96-well plate; the arrangement ensures that the 96-well plate can be placed in the first recess.
Further, set up the round hole with 96 orifice plate adaptation in the first recess, 96 orifice plate can block in the round hole, and above-mentioned setting can fix 96 orifice plate, prevents that 96 orifice plate from taking place to remove in the first recess.
Further, two opposite side surfaces of the upper part of the base are provided with second grooves, an overlapped part exists between the second grooves and the first grooves, and the depth of the second grooves is larger than that of the first grooves; above-mentioned setting, the experimenter can stretch into the second recess with the hand, gets to put 96 orifice plates more convenient.
Further, at least one sucking disc is arranged at the bottom of the base; the stability of the device in the use process is guaranteed through the arrangement.
Further, the bottom plate is rectangular, and the length and the width of the bottom plate are the same as those of the 96-well plate.
Further, a rectangular groove is formed in the upper portion of the bottom plate, and a first opening matched with the hole site of the 96-well plate is formed in the rectangular groove; optionally, the first opening is circular or rectangular; laboratory personnel load samples into the 96-well plate through the first opening and the second opening.
Further, the limit length of shielding piece is greater than first opening, shielding piece sets up in the rectangle inslot, and the height of shielding piece is less than the degree of depth of rectangle inslot, shielding piece sets up 95, leaves 1 vacancy application of sample, and slidable next shielding piece shelters from it after the application of sample is accomplished, carries out the application of sample of next hole site again.
Further, shielding piece upper portion center sets up the non-slipping block, and the experimenter slides and shields the piece more conveniently.
Further, set up the second opening with 96 orifice plate hole site adaptation on the apron, the size of second opening is less than the size of shielding piece, and the center of the side lower part between two adjacent second openings all sets up 1 through hole, through hole accessible non-slip block.
Further, arabic numerals are arranged at the corresponding positions of the first hole sites of each row on the upper part of the cover plate; english letter marks are arranged at the corresponding positions of the first hole sites of each row on the left side surface of the device; this arrangement is consistent with the 96-well plate arrangement and facilitates labeling of the loaded sample.
The utility model has the beneficial effects that: the utility model has reasonable structure; a sucker is arranged at the bottom of the base; the arrangement ensures the stability of the device in the use process; through setting up anti-pollution structure, when having guaranteed the application of sample, shelter from the piece and cover other holes around the application of sample hole, guarantee that the hole site that the application of sample was passed accurately shelters from, only the next pre-application of sample hole site top is empty, adds the wrong hole site when preventing the application of sample, has also stopped cross contamination simultaneously, easy operation.
Drawings
FIG. 1 is a schematic view of the overall structure of the present utility model;
FIG. 2 is a schematic view of the structure of the base of the present utility model;
FIG. 3 is a schematic view of an anti-contamination structure according to the present utility model;
FIG. 4 is a schematic view of the structure of the base plate of the present utility model;
FIG. 5 is a schematic view of the assembled structure of the base plate and the shielding plate of the present utility model;
FIG. 6 is a schematic view of the structure of the cover plate of the present utility model;
FIG. 7 is a schematic view of the structure of a shutter plate according to the present utility model;
in the figure, 1, a base; 2. a first groove; 3. a round hole; 4. a second groove; 5. a suction cup; 6. rectangular grooves; 7. a first opening; 8. an anti-skid block; 9. a second opening; 10. a through hole; 11. a bottom plate; 12. a cover plate; 13. and a shielding sheet.
Detailed Description
The following detailed description of the embodiments of the present utility model will be made more apparent to those skilled in the art from the following detailed description, in which the utility model is embodied in several, but not all, embodiments of the utility model. The utility model may be embodied or applied in other specific forms and features of the following examples and examples may be combined with each other without conflict, all other examples being contemplated by those of ordinary skill in the art without undue burden from the present disclosure, based on the examples of the utility model.
Example 1
Referring to fig. 1-7, a 96-well plate sample loading anti-pollution device in this embodiment includes:
the base 1 is used for placing and fixing the 96-well plate body;
the anti-pollution structure is used for preventing the sample from being added with wrong holes and protecting other samples in the holes from being cross-polluted by aerosol when the single-hole sample is added, so that the accuracy of the experiment is improved; a 96-well plate body is placed in the base 1, an anti-pollution structure is arranged at the upper part of the 96-well plate, and the anti-pollution structure is detachably connected with the base 1; the anti-pollution structure comprises a bottom plate 11, a cover plate 12 and a shielding sheet 13; the bottom plate 11 is fixedly connected with the cover plate 12, the shielding sheets 13 are arranged between the bottom plate 11 and the cover plate 12, the shielding sheets 13 can slide between the bottom plate 11 and the cover plate 12, the shielding sheets 13 are square, and each shielding sheet 13 shields one hole site; during sample addition, the shielding plate 13 covers other holes around the sample addition hole, so that accurate shielding of the hole site after sample addition is ensured, and only the upper part of the next pre-sample addition hole site is empty, so that cross contamination is avoided, and the operation is simple.
Example 2
Referring to fig. 1-2, on the basis of embodiment 1, the following technical features are added in this embodiment: (the following specific arrangements are made for the structure of the base 1): the upper part of the base 1 is provided with a first groove 2, and the length and the width of the first groove 2 are more than or equal to those of a 96-pore plate; the above arrangement ensures that a 96-well plate can be placed in the first recess 2.
The round hole 3 matched with the 96 pore plate is arranged in the first groove 2, the 96 pore plate can be clamped in the round hole 3, and the 96 pore plate can be fixed through the arrangement, so that the 96 pore plate is prevented from moving in the first groove 2.
Two opposite side surfaces of the upper part of the base 1 are provided with second grooves 4, an overlapped part exists between the second grooves 4 and the first grooves 2, and the depth of the second grooves 4 is larger than that of the first grooves 2; above-mentioned setting, the experimenter can stretch into second recess 4 with the hand, gets to put 96 orifice plates more convenient.
In some embodiments, at least one suction cup 5 is arranged at the bottom of the base 1; the arrangement ensures the stability of the device in the use process; alternatively, the suction cups 5 are provided in 4.
The bottom plate 11 is rectangular, and the length and the width of the bottom plate 11 are the same as those of the 96-well plate.
Example 3
Referring to fig. 1,3 and 7, on the basis of embodiments 1 and 2, the following technical features (the following specific arrangement is performed on the anti-pollution structure) are added: the upper part of the bottom plate 11 is provided with a rectangular groove 6, and a first opening 7 which is matched with the hole site of the 96-pore plate is arranged in the rectangular groove 6; alternatively, the first opening 7 is circular or rectangular; the experimenter loads the sample into the 96-well plate through the first opening 7 and the second opening 9.
The side length of shielding piece 13 is greater than first opening 7, shielding piece 13 sets up in rectangular channel 6, and the height of shielding piece 13 is less than rectangular channel 6's degree of depth, and shielding piece 13 sets up 95, leaves 1 vacancy and carries out the application of sample, and slidable next shielding piece 13 shelters from it after the application of sample is accomplished, carries out the application of sample of next hole site again.
The center of the upper part of the shielding piece 13 is provided with the anti-skid block 8, so that the experimenter can slide the shielding piece 13 more conveniently.
The cover plate 12 is provided with second openings 9 which are matched with the hole sites of the 96-well plate, the size of the second openings 9 is smaller than that of the shielding sheets 13, the middle of the lower part of the side surface between every two adjacent second openings 9 on the cover plate 12 is provided with through holes 10 for the anti-slip blocks 8 to pass through, the middle of the lower part of the side surface between every two adjacent second openings 9 on the cover plate 12 is provided with 1 through hole 10 for the anti-slip blocks 8 to pass through, the height of the through holes 10 is smaller than the thickness of the cover plate 12, and the transverse through holes 10 are arranged in 11 rows and 88 through holes in total; the number of the longitudinal through holes 10 is 12, the total number of the longitudinal through holes 10 is 84, the total number of the transverse through holes 10 and the longitudinal through holes 10 is 172, and the through holes 10 can pass through the anti-skid blocks 8.
An Arabic numeral mark is arranged at the corresponding position of the first hole site of each column at the upper part of the cover plate 12; english letter marks are arranged at the corresponding positions of the first hole sites of each row on the left side surface of the device; the arrangement is consistent with the 96-well plate arrangement, so that the sample adding sample can be marked; in some embodiments, arabic numerals are 1-12 and the English letters are A-H.
When the anti-pollution device is used, a 96-well plate is placed in the first groove 2, an anti-pollution structure is placed on the upper portion of the 96-well plate, a shielding sheet 13 is pushed up after sample addition is completed, sample addition can be performed in horizontal and vertical hole sites according to experimental requirements, and the shielding sheet 13 is not arranged above the sample addition hole to be subjected to next sample addition, so that the sample addition hole is effectively recorded, sample addition errors are prevented, and the pollution risks such as sample splashing and excessive aerosol are completely blocked.
The above description of embodiments is only for the understanding of the present utility model. It should be noted that it will be apparent to those skilled in the art that modifications can be made to the present utility model without departing from the principles of the utility model, and such modifications will fall within the scope of the claims.
Claims (10)
1. A96-well plate sample-adding anti-pollution device is characterized by comprising,
the base is used for placing and fixing the 96-well plate body;
the anti-pollution structure is used for preventing sample from being added with wrong holes and protecting samples in other holes from being cross-polluted by aerosol when the sample is added in a single hole; the base is internally provided with a 96-hole plate body, the anti-pollution structure is arranged at the upper part of the 96-hole plate and is detachably connected with the base; the anti-pollution structure comprises a bottom plate, a cover plate and a shielding sheet; the bottom plate and the cover plate are fixedly connected, the shielding sheets are arranged between the bottom plate and the cover plate, the shielding sheets can slide between the bottom plate and the cover plate, the shielding sheets are square, and each shielding sheet shields one hole site.
2. The 96-well plate sample-loading and contamination prevention device according to claim 1, wherein the first groove is formed in the upper portion of the base, and the length and the width of the first groove are greater than or equal to those of the 96-well plate.
3. The 96-well plate sample adding and pollution preventing device according to claim 2, wherein a round hole matched with the 96-well plate is formed in the first groove, and the 96-well plate can be clamped in the round hole; the base is characterized in that second grooves are formed in two opposite side surfaces of the upper portion of the base, overlapped portions exist between the second grooves and the first grooves, and the depth of the second grooves is larger than that of the first grooves.
4. The 96-well plate sample addition and contamination prevention device according to claim 1, wherein at least one suction cup is provided at the bottom of the base.
5. The 96-well plate sample loading and contamination prevention device according to claim 1, wherein the bottom plate is rectangular, and the length and width of the bottom plate are the same as those of the 96-well plate.
6. The 96-well plate sample loading and pollution preventing device according to claim 1, wherein a rectangular groove is formed in the upper portion of the bottom plate, and a first opening matched with a hole site of the 96-well plate is formed in the rectangular groove.
7. The 96-well plate sample loading and contamination prevention device according to claim 6, wherein the side edges of the shielding sheets are larger than the first opening, the shielding sheets are arranged in the rectangular groove, the height of the shielding sheets is smaller than the depth of the rectangular groove, and 95 shielding sheets are arranged.
8. The 96-well plate sample loading and contamination prevention device according to claim 7, wherein an anti-slip block is arranged at the center of the upper part of the shielding piece.
9. The 96-well plate sample adding and pollution preventing device according to claim 1, wherein the cover plate is provided with second openings matched with the hole sites of the 96-well plate, the size of each second opening is smaller than that of the shielding piece, and 1 through hole is formed in the center of the lower part of the side face between every two adjacent second openings.
10. The 96-well plate sample-loading and contamination prevention device according to any one of claims 1 to 9, wherein an arabic numeral mark is provided at a position corresponding to a first hole site of each column at an upper portion of the cover plate; english letter marks are arranged at the corresponding positions of the first hole sites of each row on the left side surface of the device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321288419.2U CN219273115U (en) | 2023-05-25 | 2023-05-25 | 96-hole plate sample adding anti-pollution device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321288419.2U CN219273115U (en) | 2023-05-25 | 2023-05-25 | 96-hole plate sample adding anti-pollution device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219273115U true CN219273115U (en) | 2023-06-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321288419.2U Active CN219273115U (en) | 2023-05-25 | 2023-05-25 | 96-hole plate sample adding anti-pollution device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219273115U (en) |
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2023
- 2023-05-25 CN CN202321288419.2U patent/CN219273115U/en active Active
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