CN219239651U - Nucleic acid detection reagent tube - Google Patents

Abstract

The utility model discloses a nucleic acid detection reagent tube which is used for rapidly detecting a nucleic acid sample and consists of a cover body and a reaction tube, wherein the cover body is arranged at the top end of the reaction tube and is in threaded connection with the reaction tube. The cover body is internally provided with a pressing component, a detecting component and a sample adding component; the pressing component consists of a push rod and a rubber sleeve, the detecting component consists of test paper, and the sample adding component consists of a sealing plug. The nucleic acid sample is added into a reaction tube, mixed with diluent in the reaction tube, heated by a heating device, then pressurized by a pressing component, transferred to a detection component, and finally the detection result is reflected on test paper. The utility model can rapidly detect the taken nucleic acid sample, has simple operation and accurate result, and is worth widely popularizing.

Description

Nucleic acid detection reagent tube

Technical Field

The utility model relates to the technical field of nucleic acid detection, in particular to a nucleic acid detection reagent tube.

Background

The nucleic acid detection technology is to sample the respiratory tract, blood or feces of a person to be detected, detect the sample, and then judge whether the detection result is positive to judge whether the virus is infected. For the personnel to be detected who are inconvenient to go to a hospital or keep in isolation at home, medical care is often required to carry out the detection of going to the gate, and the result can be obtained after waiting for a few hours. Therefore, a detection device capable of rapidly detecting and outputting results is needed, and the detection results can be rapidly checked when the door is opened for detection, or the home isolation personnel can automatically detect the detection results.

Disclosure of Invention

The utility model aims to provide a nucleic acid detection reagent tube, which solves the problems in the prior art and can realize the purpose of rapidly detecting a nucleic acid detection sample and rapidly outputting a result.

In order to achieve the above object, the present utility model provides the following solutions: the utility model provides a nucleic acid detection reagent tube, which comprises a cover body and a reaction tube, wherein the cover body is in threaded connection with the top end of the reaction tube;

the top end of the cover body is in threaded connection with a sealing cover; a guide hole is formed in the center of the sealing cover, and an air outlet hole and a sample adding hole are respectively formed in two sides of the guide hole;

a first inner cavity corresponding to the air outlet hole, a second inner cavity corresponding to the guide hole and a third inner cavity corresponding to the sample adding hole are formed in the cover body; the first inner cavity is internally provided with a detection assembly, the second inner cavity is internally provided with a pressing assembly in a sliding manner, and the third inner cavity is internally provided with a sample adding assembly;

the pressing assembly comprises a push rod and a rubber sleeve, the rubber sleeve is fixedly arranged at the bottom of the push rod, the push rod downwards penetrates through the guide hole, and the rubber sleeve is in sliding connection with the side wall of the second inner cavity;

the detection assembly comprises test paper, the test paper is installed in the first inner cavity, a liquid inlet is formed in the bottom of the first inner cavity, the liquid inlet is connected with a connector, and a catheter is sleeved at the other end of the connector;

the sample adding assembly is a sealing plug, a pierceable sealing membrane is arranged between the top end of the sealing plug and the sealing cover, a gap is reserved between the bottom end of the sealing plug and the third inner cavity, and the bottom of the third inner cavity is communicated with the second inner cavity;

the second inner cavity is used for containing diluent, and one end of the conduit, which is far away from the joint, extends into the diluent;

the cover body is made of transparent materials;

the outer side wall of the cover body is provided with a gripper;

the joint and the first inner cavity are of an integrated structure.

The utility model discloses the following technical effects: the device has the advantages that the nucleic acid sampling sample can be rapidly detected, the device has a simple structure, low cost and simple and convenient operation, the rapid detection of suspected cases is convenient, no interference is caused in the detection process, and the accuracy of nucleic acid detection is improved; the detection can be carried out by medical staff at home or by isolation staff at home, so that the safety of nucleic acid detection is improved, and the normalization of nucleic acid detection is facilitated.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions of the prior art, the drawings that are needed in the embodiments will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present utility model, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic view of a longitudinal cross-sectional structure of the present utility model;

FIG. 2 is an enlarged view of A in FIG. 1;

FIG. 3 is a top view of the seal cap;

FIG. 4 is a schematic diagram of the overall structure of the present utility model;

wherein, 1-cover; 2-a reaction tube; 3-a gripper; 4-sealing the cover; 5-a guide hole; 6-an air outlet hole; 7-a sample adding hole; 8-a first lumen; 9-test paper; 10-linker; 11-a catheter; 12-pushing rod; 13-a rubber sleeve; 14-sealing sleeve; 15-a second lumen; 16-a third lumen; 17-liquid inlet hole.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

In order that the above-recited objects, features and advantages of the present utility model will become more readily apparent, a more particular description of the utility model will be rendered by reference to the appended drawings and appended detailed description.

Referring to FIGS. 1 to 4, the present utility model provides a nucleic acid detecting reagent tube, the whole device is divided into two parts, namely a cover 1 and a reaction tube 2, and the cover 1 is screw-mounted on the top of the reaction tube 2.

Specifically, the cover body 1 is made of transparent polypropylene material, is made of the same material as a medical injector, and is internally provided with threads at the bottom end of the cover body 1; the reaction tube 2 is a quartz glass threaded test tube, the tube orifice is provided with threads, and the tube orifice is matched with the threads of the cover body 1; the dimensions of the reaction tube 2 in this example were 36X 155mm (outer diameter X total height of test tube). The cover body 1 is in threaded connection with the reaction tube 2, so that the tightness of the whole device is improved, and meanwhile, the cover body 1 is made of transparent materials, so that the reaction condition inside the cover body 1 can be observed conveniently.

The top of the cover body 1 is in threaded connection with a sealing cover 4, a guide hole 5 is formed in the center of the sealing cover 4, and air outlet holes 6 and sample adding holes 7 are respectively formed in two sides of the guide hole 5; a first inner cavity 8 corresponding to the air outlet hole 6, a second inner cavity 15 corresponding to the guide hole 5 and a third inner cavity 16 corresponding to the sample adding hole 7 are respectively formed in the cover body 1; the first inner cavity 8 is internally provided with a detection component, the second inner cavity 15 is internally provided with a pressing component in a sliding mode, and the third inner cavity 16 is internally provided with a sample adding component.

Specifically, the detection component is test paper 9; the pressing assembly consists of a push rod 12 and a rubber sleeve 13, the rubber sleeve 13 is fixedly arranged at the bottom of the push rod 12, and the push rod 12 downwards penetrates through the guide hole 5; the sample adding component is a sealing plug 14 arranged in a third inner cavity 16, the sealing plug 14 is made of rubber, and a layer of pierceable sealing membrane is arranged between the sealing sleeve 14 and the sealing cover 4; the arrangement of the guide holes 5 can keep stable in the pressing process of the push rod 12, and the push rod cannot deviate; the test paper 9 is put into the first inner cavity 8 in advance, so that the test paper 9 can be prevented from being polluted, and the stability of nucleic acid detection is improved; the pierceable sealing membrane is made of aluminum foil material, so that the top end of the sealing plug 14 can be prevented from being polluted, when the injector is used for injecting a sample into the reaction tube 2, the sealing plug 14 can keep the inside of the reaction tube 2 in a sealing state at all times, after the injector is pulled out, the sealing plug 14 is contracted, the sealing degree is not influenced by pores, a gap is reserved between the bottom end of the sealing plug 14 and the third inner cavity 16, the needle is prevented from being stabbed too long and being deviated, and the operation difficulty is reduced.

A liquid inlet hole 17 is formed in the bottom of the first inner cavity 8, and a joint 10 is connected with the first inner cavity 8 at the position of the liquid inlet hole 17; the joint 10 is an integral structure with the first inner cavity 8, and in this embodiment, the specific size of the joint 10 is 2.8x15mm (outer diameter x length); the other end of the joint 10 is sleeved with a guide pipe 11, the inner diameter of the guide pipe 11 is matched with the outer diameter of the joint 10, the guide pipe 11 is tightly sleeved on the joint 10, the guide pipe 11 is a common hard plastic pipe, and the other end of the guide pipe 11 extends into the diluent in the reaction pipe 2.

In this embodiment, the diluent in the reaction tube 2 is not more than 2/3 of the height of the reaction tube 2 and not less than 1/2 of the height of the reaction tube 2, the conduit 11 extends into the diluent in the reaction tube 2, and the end of the conduit 11 is 1cm from the bottom surface of the reaction tube 2.

The outer side wall of the bottom of the cover body 1 is provided with a grip 3, and the grip 3 can keep the whole device stable when the push rod is pressed. After the push rod 12 is pressed, the mixed liquid enters the first inner cavity 8 through the guide pipe 11 to react with the test paper 9, and the mixed liquid is pressed at a constant speed during pressing, so that the mixed liquid is prevented from being sprayed out of the air outlet hole 6.

The working principle of the utility model is as follows: the diluent is put into the reaction tube 2 in advance, the cover body 1 and the reaction tube 2 are screwed tightly, a sampled sample is injected into the reaction tube 2 through the sealing plug 14 by the injector, the sample is immediately mixed with the diluent, the bottom of the reaction tube 2 is heated by the heating device after the mixing is finished, the push rod 12 is pressed after the heating is finished, the sample mixed solution enters the first inner cavity 8 from the guide tube 11 to react with the test paper 9, and finally the detection result is reflected on the test paper 9. The device can be used for rapidly detecting the sample of the person to be detected, has the advantages of simple structure, low cost and simple and convenient operation, is convenient for rapidly detecting suspected cases, has no interference in the detection process, and improves the accuracy of nucleic acid detection; the detection can be carried out by medical staff at home or by isolation staff at home, so that the safety of nucleic acid detection is improved, and the normalization of nucleic acid detection is facilitated.

In the description of the present utility model, it should be understood that the terms "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present utility model, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present utility model.

The above embodiments are only illustrative of the preferred embodiments of the present utility model and are not intended to limit the scope of the present utility model, and various modifications and improvements made by those skilled in the art to the technical solutions of the present utility model should fall within the protection scope defined by the claims of the present utility model without departing from the design spirit of the present utility model.

Claims (8)

1. A nucleic acid detection reagent tube for rapid detection of a nucleic acid sample, characterized in that: the device comprises a cover body (1) and a reaction tube (2), wherein the cover body (1) is in threaded connection with the top end of the reaction tube (2);

the top end of the cover body (1) is connected with a sealing cover (4) in a threaded manner; a guide hole (5) is formed in the center of the sealing cover (4), and an air outlet hole (6) and a sample adding hole (7) are respectively formed in two sides of the guide hole (5);

a first inner cavity (8) corresponding to the air outlet hole (6), a second inner cavity (15) corresponding to the guide hole (5) and a third inner cavity (16) corresponding to the sample adding hole (7) are formed in the cover body (1); the first inner cavity (8) is internally provided with a detection assembly, the second inner cavity (15) is internally provided with a pressing assembly in a sliding mode, and the third inner cavity (16) is internally provided with a sample adding assembly.

2. The nucleic acid detecting reagent tube according to claim 1, wherein: the pressing assembly comprises a push rod (12) and a rubber sleeve (13), the rubber sleeve (13) is fixedly arranged at the bottom of the push rod (12), the push rod (12) downwards penetrates through the guide hole (5), and the rubber sleeve (13) is in sliding connection with the side wall of the second inner cavity (15).

3. The nucleic acid detecting reagent tube according to claim 1, wherein: the detection assembly comprises test paper (9), the test paper (9) is installed in the first inner cavity (8), a liquid inlet hole (17) is formed in the bottom of the first inner cavity (8), the liquid inlet hole (17) is connected with a connector (10), and a guide pipe (11) is sleeved at the other end of the connector (10).

4. The nucleic acid detecting reagent tube according to claim 1, wherein: the sample adding assembly is a sealing plug (14), a pierceable sealing membrane is arranged between the top end of the sealing plug (14) and the sealing cover (4), a gap is reserved between the bottom end of the sealing plug (14) and the third inner cavity (16), and the bottom of the third inner cavity (16) is communicated with the second inner cavity (15).

5. A nucleic acid detecting reagent tube according to claim 3, wherein: the second inner cavity (15) contains diluent, and one end of the conduit (11) far away from the joint (10) stretches into the diluent.

6. The nucleic acid detecting reagent tube according to claim 1, wherein: the cover body (1) is made of transparent materials.

7. The nucleic acid detecting reagent tube according to claim 1, wherein: the outer side wall of the cover body (1) is provided with a grip (3).

8. A nucleic acid detecting reagent tube according to claim 3, wherein: the joint (10) and the first inner cavity (8) are of an integrated structure.

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