CN219185235U - Universal rat enema device - Google Patents

Universal rat enema device Download PDF

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Publication number
CN219185235U
CN219185235U CN202223264741.XU CN202223264741U CN219185235U CN 219185235 U CN219185235 U CN 219185235U CN 202223264741 U CN202223264741 U CN 202223264741U CN 219185235 U CN219185235 U CN 219185235U
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tube
air bag
administration
inflation
wall
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李�杰
刘阿慧
刘宇轩
张学红
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First Hospital of Lanzhou University
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First Hospital of Lanzhou University
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The utility model discloses a general rat enema device which comprises a dosing tube, a dosing opening, a first air bag and a second air bag, wherein the dosing opening is arranged at the bottom end of the dosing tube, a round blind end is arranged at the top end of the dosing tube, the second air bag is arranged on the outer wall of the dosing tube at the position of the round blind end, the first air bag is arranged on the outer wall of the dosing tube below the second air bag, a first inflation and deflation tube is arranged on one side of the dosing tube, and a second inflation and deflation tube is arranged on the other side of the dosing tube. The utility model adopts the double air bags to seal the intestinal administration part, thereby prolonging the residence time of the medicine in the intestinal tract, exerting the medicine effect and the action time to the maximum extent, being convenient for accurately judging the depth of entering the intestinal tract of the rat, improving the clysis effect, and the medicine liquid is uniformly sprayed in the colon and fully contacted with the intestinal tract, thereby improving the medicine absorption effect.

Description

Universal rat enema device
Technical Field
The utility model relates to the technical field of enema devices, in particular to a general rat enema device.
Background
In the research of colorectal diseases, enema administration is one of the common modeling methods for experimental rats, and no special enema device for experimental rats is available in the market, so that when a colon cancer model is established, a catheter, a polyethylene catheter or a gastric lavage needle is inserted into anus, and liquid medicine is input through a syringe.
In the operation process, because the intestinal tract shape of the experimental rat is different from that of human beings, when the traditional enema device is used for injection, the liquid medicine can flow to the cecum or even the small intestine end through the colon of the rat or flow out from the anus after struggling by the rat, so that the drug effect and the action time can not be exerted to the maximum extent, and the modeling is failed; secondly, the intestinal cavity of the experimental rat is narrow and the intestinal mucosa is thin, and the enema tools with different materials and specifications are easy to damage the intestinal tract to different degrees, so that the modeling effect is affected, even the death of the rat is caused, the existing enema tools have no scale marks, the depth of the intestinal tract of the rat can not be accurately judged, and the enema effect is affected; the top end of the currently used enema device is a single hole, the liquid medicine is easy to spray to a far place in the pouring process, and the contact area with the intestinal tract is limited, so that the medicine absorption is affected; therefore we propose a general-purpose rat enema device to solve the above problems.
Disclosure of Invention
The utility model aims to provide a general rat enema device which is used for solving the problems in the background technology.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a general type rat enema device, includes administration tube, annotates medicine mouth, first gasbag and second gasbag, annotate the medicine mouth and set up in the bottom of administration tube, just the top of administration tube is provided with the blunt blind end of circle, the second gasbag sets up on the administration tube outer wall of blunt blind end position department of circle, first gasbag sets up on the administration tube outer wall of second gasbag below, one side of administration tube is provided with first inflation and deflation pipe, just the top and the first gasbag intercommunication of first inflation and deflation pipe, the first check valve joint is installed to the bottom of first inflation and deflation pipe, just be provided with the first instruction sacculus on the first inflation and deflation pipe outer wall of first check valve joint position department, just the opposite side of administration tube is provided with the second inflation and deflation pipe, just the top and the second gasbag intercommunication of second inflation and the second gasbag of second inflation pipe, the second check valve joint is installed to the bottom of second inflation and is provided with the second instruction and deflates the balloon joint, the second instruction ball is located and is shown the deflation pipe to be provided with the inflation and deflation pipe on the second instruction and the second inflation and deflation pipe.
Preferably, the administration tube is made of silica gel, is soft and flexible, and is not easy to damage intestinal tracts.
Preferably, the outer surface of the administration tube is provided with scale areas along the axis of the tube body, and the inner parts of the scale areas are marked with equidistant scale marks, so that the depth of intestinal tracts of rats can be accurately judged, and the clysis effect is improved.
Preferably, a syringe is arranged at one side of the administration tube for pushing air and liquid medicine.
Preferably, the upper parts of the first inflation and deflation pipe and the second inflation and deflation pipe are tightly adhered to the outer wall of the administration pipe, so that the integration of the first inflation and deflation pipe, the second inflation and deflation pipe and the administration pipe is ensured.
Preferably, the first air bag and the second air bag are adhered to the outer wall of the administration tube, so that the first air bag and the second air bag can be fixed conveniently.
Preferably, the medicine feeding pipe outer wall between the first air bag and the second air bag is provided with equidistant medicine outlet holes, the medicine outlet holes are oval and uniformly and symmetrically distributed, the number of the medicine outlet holes is 10, the medicine liquid is convenient to uniformly spray in the colon and fully contact with the intestinal tract, and the medicine absorption effect is improved.
Compared with the prior art, the utility model has the beneficial effects that: the general rat enema device adopts the double air bags to seal the intestinal administration part, so that the residence time of the medicine in the intestinal tract is prolonged, the medicine effect and the acting time are exerted to the maximum extent, the depth of the medicine entering the intestinal tract of the rat is convenient to accurately judge, the enema effect is improved, the medicine liquid is uniformly sprayed in the colon and fully contacted with the intestinal tract, and the medicine absorption effect is improved;
(1) The method comprises the steps of inserting a drug delivery pipe into anus of a rat, connecting an injector with the second one-way valve joint, inflating the second air bag through the second air inflation and deflation pipe, estimating the pressure in the second air bag through sensing the size of the second air bag, connecting the injector with liquid medicine to a drug injection port, pushing the liquid medicine into the drug delivery pipe, spraying the liquid medicine on the colon part through a drug outlet, and repeating the steps to inflate the first air bag to inflate the liquid medicine after the injection of the liquid medicine is completed, wherein the two air bags can seal the two ends of the colon drug delivery part to prevent the liquid medicine from flowing far and near or leaking outwards, so that the residence time of the medicine in the intestinal tract is prolonged, the drug effect and the action time can be exerted to the maximum extent, the distance between the two air bags can be adjusted according to the experimental requirement, and the modeling is better accurate;
(2) The drug administration tube, the scale area and the scale mark are arranged, so that the drug administration tube is made of silica gel, is soft and flexible, is not easy to damage the intestinal tract, and the scale area and the scale mark are convenient for accurately judging the depth of the rat intestinal tract, so that the clysis effect is improved;
(3) Through being provided with out the medicine hole, go out the medicine hole and be oval and be even symmetric distribution, quantity is 10, and the liquid medicine of being convenient for evenly spray in the colon and fully contact with the intestinal, has improved the medicine absorption effect.
Drawings
FIG. 1 is a schematic elevational view of the present utility model;
FIG. 2 is a schematic view of a partial structure of a drug administration tube according to the present utility model;
FIG. 3 is a schematic view of a first check valve connector according to the present utility model;
FIG. 4 is a schematic view of a second check valve connector according to the present utility model;
FIG. 5 is a schematic diagram of the enema operation of this utility model.
In the figure: 1. a drug administration tube; 2. a medicine injection port; 3. a syringe; 4. a first check valve joint; 5. a first inflation and deflation line; 6. a first air bag; 7. a rounded blind end; 8. a second air bag; 9. a scale area; 10. scale marks; 11. a second inflation and deflation line; 12. a second check valve joint; 13. a medicine outlet hole; 14. a first indicator balloon; 15. the second indicates a balloon.
Detailed Description
The technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model, and all other embodiments obtained by those skilled in the art without making any inventive effort based on the embodiments of the present utility model are within the scope of protection of the present utility model.
Referring to fig. 1-5, an embodiment of the present utility model is provided: the utility model provides a general type rat enema device, includes administration tube 1, injection port 2, first gasbag 6 and second gasbag 8, and injection port 2 sets up in the bottom of administration tube 1, and the top of administration tube 1 is provided with blunt blind end 7;
the administration tube 1 is made of silica gel, is soft and flexible, and is not easy to damage the intestinal tract;
the outer surface of the administration tube 1 is provided with the scale areas 9 along the axis of the tube body, and the inner parts of the scale areas 9 are marked with equidistant scale marks 10, so that the depth of the administration tube entering the intestinal canal of a rat can be accurately judged, and the clysis effect is improved;
one side of the administration tube 1 is provided with a syringe 3 for pushing air and liquid medicine;
the second air bag 8 is arranged on the outer wall of the administration tube 1 at the position of the round blind end 7;
the first air bag 6 is arranged on the outer wall of the administration tube 1 below the second air bag 8;
a first inflation and deflation pipe 5 is arranged on one side of the administration tube 1, and the top end of the first inflation and deflation pipe 5 is communicated with a first air bag 6;
the bottom end of the first inflation and deflation pipe 5 is provided with a first one-way valve joint 4, a first indication balloon 14 is arranged on the outer wall of the first inflation and deflation pipe 5 at the position of the first one-way valve joint 4, and the first indication balloon 14 is communicated with the first inflation and deflation pipe 5;
a second inflation and deflation pipe 11 is arranged on the other side of the administration tube 1, and the top end of the second inflation and deflation pipe 11 is communicated with a second air bag 8;
the bottom end of the second inflation and deflation pipe 11 is provided with a second one-way valve joint 12, the outer wall of the second inflation and deflation pipe 11 at the position of the second one-way valve joint 12 is provided with a second indication balloon 15, and the second indication balloon 15 is communicated with the second inflation and deflation pipe 11;
the upper parts of the first inflation and deflation pipe 5 and the second inflation and deflation pipe 11 are tightly adhered to the outer wall of the administration pipe 1, so that the integration of the first inflation and deflation pipe 5, the second inflation and deflation pipe 11 and the administration pipe 1 is ensured;
the first air bag 6 and the second air bag 8 are adhered to the outer wall of the administration tube 1, so that the first air bag 6 and the second air bag 8 are convenient to fix;
the outer wall of the administration tube 1 between the first air bag 6 and the second air bag 8 is provided with equidistant medicine outlet holes 13, the medicine outlet holes 13 are oval and uniformly and symmetrically distributed, the number of the medicine outlet holes 13 is 10, so that medicine liquid is uniformly sprayed in the colon and fully contacted with the intestinal tract, and the medicine absorption effect is improved.
When the embodiment of the application is used, the following steps are adopted: firstly, the space between the first air bag 6 and the second air bag 8 is determined according to the experimental requirement and is adhered on the outer wall of the administration tube 1, the anesthetized rat head is grasped and fixed at a low-hip high position, the anus is fully exposed, secondly, the administration tube 1 is moistened by normal saline and is gently and slowly inserted into the anus of the rat, the administration tube 1 is sent to the colon position 7-8cm away from the anus according to the scale mark 10, at this time, the injector 3 is connected to the second one-way valve joint 12, when the injector 3 supplies pressurized air, the air reaches the inside of the second air bag 8 through the second inflation and deflation tube 11 and fills the second air bag 8, the injector 3 can be removed, the pressure in the second air bag 8 can be estimated by sensing the size of the second indication balloon 15, after the second air bag 8 is confirmed to be inflated, the injector 3 filled with liquid medicine is connected to the medicine injection port 2, the liquid medicine is pushed into the administration tube 1, the liquid medicine is sprayed on the colon part through the medicine outlet hole 13, when the liquid medicine injection is finished, a new injector 3 is connected to the first one-way valve joint 4, when the injector 3 is supplied with pressurized air, the air reaches the inside of the first air bag 6 through the first inflation and deflation pipe 5 and is inflated, the injector 3 can be removed, the pressure in the first air bag 6 can be estimated by sensing the size of the first indication balloon 14, at the moment, the sealing area formed by the inflation of the two air bags is a local action site of the medicine, the double air bags seal the intestinal administration part, and because the time required for the anesthesia recovery of a rat is 1-2min, the air bag inflation state can be kept during the period to prolong the residence time of the medicine in the intestinal tract, the injector 3 is used for evacuating the air in the two air bags when the medicine administration pipe 1 is evacuated, then the medicine administration pipe 1 is slowly withdrawn from the intestinal tract of the rat, the operation is finished, because the material of the administration tube 1 is silica gel, the quality is soft and flexible, the damage to the intestinal tract is difficult to cause, the setting of scale area 9 and scale mark 10 is convenient for accurately judge the intestinal depth of entering the rat, the clysis effect is improved, and the medicine outlet holes 13 are oval and are evenly symmetrically distributed, the quantity is 10, the medicine liquid is convenient to evenly spray in the colon and fully contact with the intestinal tract, the medicine absorption effect is improved, the structural design of the general rat clysis device is simple, the assembly and the use are simpler, the practicability is strong, and the work of the general rat clysis device is completed.

Claims (7)

1. The utility model provides a general type rat enema device, its characterized in that, including administration tube (1), injection mouth (2), first gasbag (6) and second gasbag (8), injection mouth (2) set up in the bottom of administration tube (1), just the top of administration tube (1) is provided with round dull end (7), second gasbag (8) set up on the administration tube (1) outer wall of round dull end (7) position department, first gasbag (6) set up on the administration tube (1) outer wall of second gasbag (8) below, one side of administration tube (1) is provided with first gas-filled air-release tube (5), just the top and the first gasbag (6) intercommunication of first gas-filled air-release tube (5), first check valve joint (4) are installed to the bottom of first gas-filled air-release tube (5), just be provided with first instruction balloon (14) on the first gas-filled tube (5) outer wall of first check valve joint (4) position department, and first balloon (14) are installed on the administration tube (1) outer wall of second gasbag (1) below, one side of administration tube (1) is provided with first gas-filled air-release tube (11) and second gas-filled air-release tube (11) and the other side of second gas-filled air-release tube (11), and a second indication balloon (15) is arranged on the outer wall of the second inflation and deflation pipe (11) at the position of the second one-way valve joint (12), and the second indication balloon (15) is communicated with the second inflation and deflation pipe (11).
2. A universal rat enema device according to claim 1, wherein: the administration tube (1) is made of silica gel.
3. A universal rat enema device according to claim 1, wherein: the external surface of the administration tube (1) is provided with scale areas (9) along the axis of the tube body, and the inside of the scale areas (9) is marked with equidistant scale marks (10).
4. A universal rat enema device according to claim 1, wherein: one side of the administration tube (1) is provided with a syringe (3).
5. A universal rat enema device according to claim 1, wherein: the upper parts of the first inflation and deflation pipe (5) and the second inflation and deflation pipe (11) are tightly adhered to the outer wall of the administration pipe (1).
6. A universal rat enema device according to claim 1, wherein: the first air bag (6) and the second air bag (8) are adhered to the outer wall of the administration tube (1).
7. A universal rat enema device according to claim 1, wherein: the drug delivery tube comprises a drug delivery tube (1) and is characterized in that drug outlet holes (13) which are equidistant are formed in the outer wall of the drug delivery tube (1) between the first air bag (6) and the second air bag (8), the drug outlet holes (13) are oval and uniformly and symmetrically distributed, and the number of the drug outlet holes (13) is 10.
CN202223264741.XU 2022-12-07 2022-12-07 Universal rat enema device Active CN219185235U (en)

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Application Number Priority Date Filing Date Title
CN202223264741.XU CN219185235U (en) 2022-12-07 2022-12-07 Universal rat enema device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223264741.XU CN219185235U (en) 2022-12-07 2022-12-07 Universal rat enema device

Publications (1)

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CN219185235U true CN219185235U (en) 2023-06-16

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117883651A (en) * 2024-01-17 2024-04-16 中国人民解放军空军军医大学 Gastroenterology intestines and stomach ware of dosing

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117883651A (en) * 2024-01-17 2024-04-16 中国人民解放军空军军医大学 Gastroenterology intestines and stomach ware of dosing

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