CN210250853U - Balloon type stomach tube for establishing gastroesophageal reflux animal model - Google Patents
Balloon type stomach tube for establishing gastroesophageal reflux animal model Download PDFInfo
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- CN210250853U CN210250853U CN201920809459.4U CN201920809459U CN210250853U CN 210250853 U CN210250853 U CN 210250853U CN 201920809459 U CN201920809459 U CN 201920809459U CN 210250853 U CN210250853 U CN 210250853U
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Abstract
The utility model relates to a sacculus formula stomach tube for establishing gastroesophageal reflux animal model, including filling pipe, gas tube, aerify sacculus, venthole, pull seal wire, warning sign, inflation inlet, fill in mouthful, shutoff cap, scale mark, operation suggestion sign, foam-rubber cushion, PH test paper, inside the gas tube runs through filling the pipe, the gas tube end is connected with aerifing the sacculus, and the head end is the inflation inlet, is connected with the syringe, and the venthole has been seted up to the gas tube end, fills the pipe surface and is close to aerifing the sacculus end and be equipped with operation suggestion sign, keeps away from the end and is equipped with the warning sign, and the warning sign is located to the scale mark between operation suggestion sign, fills the pipe head end and fills in mouthful, and shutoff cap and fill in mouthful and be connected, fill intraduct and still be equipped with and pull the. Its advantages are: the utility model provides an among the prior art easy tub, the problem of easy aversion of taking off that appear when the animal is moulded, improved animal moulding success rate, and convenient to use.
Description
Technical Field
The utility model relates to the technical field of animal modeling medical equipment, in particular to a balloon type stomach tube for establishing a gastroesophageal reflux animal model.
Background
Gastroesophageal reflux cough (GERC) refers to a clinical syndrome in which gastric acid and other gastric contents reflux into the esophagus, resulting in chronic cough as the only or major symptom, and is a special type of gastroesophageal reflux disease, also known as reflux cough syndrome, which is also a common cause of chronic cough. With the popularization of the diagnosis and treatment knowledge of the GERC in China and the westernized lifestyle accompanying the development of social economy, the number of the GERCs diagnosed in recent years is increasing, and the effective treatment of the patients is a difficult problem which needs to be solved clinically.
For basic animal studies on GERC, an esophageal hydrochloric acid infusion method is commonly used to establish a model of gastroesophageal reflux animals (animals commonly used are guinea pigs). During the molding process, researchers need to slowly pour 0.1mol/L hydrochloric acid into the middle and lower esophagus of guinea pigs at a constant speed for 20min by using a micro-injection pump through a certain pipeline to simulate gastroesophageal reflux or injury stimulation of esophageal mucosa.
Most of the selected pipelines in the process of the research are neonatal stomach tubes, so that the diameters are not uniform, the lengths of the stomach tubes cannot be determined, the phenomena of backflow of perfusion liquid, soft stomach tube material and difficulty in insertion and the like are easy to occur, and the death of experimental guinea pigs and the failure of model building are easy to cause; on the other hand, during the intubation process and the hydrochloric acid filling process, the tube is often pulled out or displaced due to the struggle of the guinea pig, and the molding success rate of the gastroesophageal reflux guinea pig model is greatly influenced.
The Chinese patent application: CN201524343U discloses a medical stomach tube, which comprises a stomach tube main body, wherein a side hole is formed in the side wall of the front end of the stomach tube main body, a stomach tube connector is formed at the tail end of the stomach tube main body, and the medical stomach tube also comprises a hollow balloon and an inflation tube; the hollow balloon is attached to the outer side of the stomach tube main body and is away from the stomach tube interface by a preset distance; the inflation tube extends towards the stomach tube interface along the direction parallel to the stomach tube main body, one end of the inflation tube, which is far away from the stomach tube interface, is communicated with the hollow saccule, and the other end, which is close to the stomach tube interface, is provided with an inflation tube interface. However, the patent fails to solve the problems of backflow of perfusate, better cannula length and the like, and has certain defects.
Aiming at the defects, the balloon type stomach tube for establishing the gastroesophageal reflux animal model is convenient to use, the opening of the pipeline is fixed at the middle and lower segments of the esophagus of an animal after the inflatable balloon is inflated, the inflatable balloon cannot be separated or displaced due to struggle of the animal, the hydrochloric acid is ensured to slowly flow in, the mucous membrane of the middle and lower segments of the esophagus of the animal is stimulated to establish the gastroesophageal reflux model, and the success rate of model building in animal research is improved.
Disclosure of Invention
The utility model aims at providing a sacculus formula stomach tube for establishing the palirrhea animal model of gastroesophageal to the not enough of prior art.
In order to achieve the purpose, the utility model adopts the technical proposal that:
a sacculus stomach tube for establishing a gastroesophageal reflux animal model comprises a perfusion device, wherein the perfusion device comprises a perfusion tube (1), a head end (101) of the perfusion tube, a middle section (102) of the perfusion tube, a tail end (103) of the perfusion tube and a perfusion opening (15), the sacculus stomach tube also comprises an inflating device, an identification device and a backflow preventing device,
the inflation device comprises an inflation tube (2), a head end (201) of the inflation tube, a middle section (202) of the inflation tube, a tail end (203) of the inflation tube, an inflation balloon (3), an air outlet (4) and an inflation opening (7);
the identification device comprises a warning identification (6), scale marks (10) and an operation prompt identification (11);
the backflow prevention device comprises a plugging cap (9), a spongy cushion (12) and a PH test paper (13);
the perfusion tube (1) is divided into three sections: the device comprises a head end (101) of a perfusion tube, a middle section (102) of the perfusion tube and a tail end (103) of the perfusion tube, wherein the head end (101) of the perfusion tube and the tail end (103) of the perfusion tube are in seamless fixed connection through the middle section (102) of the perfusion tube; the inflation tube (2) is divided into three sections: the air inflation pipe comprises an air inflation pipe head end (201), an air inflation pipe middle section (202) and an air inflation pipe tail end (203), wherein the air inflation pipe head end (201) and the air inflation pipe tail end (203) are in seamless fixed connection through the air inflation pipe middle section (202);
the perfusion tube head end (101) is fixedly connected with a perfusion opening (15), the middle section (202) of the inflation tube and the tail end (203) of the inflation tube are fixedly connected and run through the middle section (102) of the perfusion tube, the head end (201) of the inflation tube is fixedly connected with an inflation opening (7) in a seamless manner, the tail end (203) of the inflation tube is connected with an inflation saccule (3), the tail end (203) of the inflation tube is provided with an air outlet (4), the outer surface of the middle section (102) of the perfusion tube is provided with an operation prompt mark (11) close to the end of the inflation saccule (3), the end far away from the inflation saccule (3) is provided with a warning mark (6), a scale mark (10) is arranged between the warning mark (6) and the operation prompt mark (11), the head end (101) of the perfusion tube is fixedly connected with the perfusion opening (15), the perfusion opening (15) is detachably connected with a plugging cap, the PH test paper (13) is positioned at one side of the perfusion opening (15) close to the middle section (102) of the perfusion tube, and the spongy cushion (12) is positioned at one side of the perfusion opening (15) far away from the middle section (102) of the perfusion tube;
the balloon type gastric tube further comprises a traction guide wire (5) and a handle (8), one end of the traction guide wire (5) is fixedly connected with the handle (8), and the other end of the traction guide wire penetrates into the perfusion tube (1) from the perfusion opening (15) to the tail end (103) of the perfusion tube.
As a preferred embodiment of the utility model, the total length of the balloon type gastric tube is 20-40 cm.
As a preferred embodiment of the present invention, the diameter of the perfusion tube (1) is 0.1-1.5 cm.
As a preferred embodiment of the invention, the diameter of the inflatable balloon (3) is 0.6-2.5 cm.
As a preferred embodiment of the utility model, the number of the air outlet holes (4) is 1-5.
As a preferred embodiment of the utility model, the warning mark (6) is a red mark, and the distance between the warning mark (6) and the inflatable saccule (3) is 5-10 cm.
As a preferred embodiment of the utility model, the operation prompt mark (11) is a yellow mark, and the distance between the operation prompt mark (11) and the inflatable balloon (3) is 2-5 cm.
As a preferred embodiment of the present invention, the balloon-type gastric tube is a disposable balloon-type gastric tube.
The distance between the connection starting end of the perfusion tube (1) and the inflation tube (2) and the inflatable balloon (3) is a middle section (102) of the perfusion tube, and the other two ends of the perfusion tube (1) are respectively a head end (101) and a tail end (103) of the perfusion tube;
the distance between the connection starting end of the filling pipe (1) and the inflation pipe (2) and the operation prompt mark (11) is an inflation pipe middle section (202), and the other two ends of the inflation pipe (2) are respectively an inflation pipe head end (201) and an inflation pipe tail end (203).
As a preferred embodiment of the present invention, the perfusion tube (1) is made of an elastic silica gel material after aseptic sterilization.
As a preferred embodiment of the utility model, the warning mark (6) is used for prompting the length of the intubation tube of an operator and helping the operator to quickly judge the insertion length of the gastric tube (when the red warning mark (6) is positioned at the position of the respiration opening of the animal, the insertion length of the gastric tube is just proper); the operation prompt mark (11) is used for prompting an operator that when the stomach tube extends into 5-10cm from the respiratory opening and just reaches the throat part of the animal, the operator needs to lift the lower jaw of the animal so that the stomach tube can be smoothly inserted into the throat part.
The utility model has the advantages that:
1. the utility model provides a sacculus formula stomach tube is used to animal, simple structure, convenient to use ensures can not deviate from or shift because of struggling of animal at the molding in-process, and the unexpected death that the significantly reduced arouses the animal at the molding process improves the molding success rate of animal research.
2. The utility model can fix the insertion stability of the stomach tube by the arranged inflatable balloon, and the arranged identification device can accurately judge the insertion length of the stomach tube, thereby reducing the workload of an operator and improving the intubation rate; the backflow prevention device can prompt an operator to backflow the perfusate, improves the molding success rate, and has strong practicability.
Drawings
Fig. 1 is a schematic diagram of the overall structure of the present invention.
Fig. 2 is a schematic view of the structure inside the circle in fig. 1, namely a schematic view of the structure inside the pouring opening.
FIG. 3 is a schematic cross-sectional view of the middle section of the perfusion tube and the middle section of the inflation tube.
FIG. 4 is a schematic view showing a connection structure of the distal end of the inflation tube and the air outlet.
Fig. 5 is a schematic structural view of the inflatable balloon when deflated in a use state.
Fig. 6 is a schematic view of the inflated balloon inflated during use.
Detailed Description
The present invention will be further described with reference to the following detailed description. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that various changes and modifications can be made by those skilled in the art after reading the disclosure of the present invention, and such equivalents also fall within the scope of the appended claims.
1. A perfusion tube 101, a perfusion tube head end 102 perfuses a tube mid-section.
103. Filling pipe end 2, inflation pipe 201, inflation pipe head end
202. Middle section 203 of inflation tube, tail end 3 of inflation tube and inflation balloon
4. Air outlet 5, traction guide wire 6 and warning mark
7. Inflation inlet 8, handle 9, plugging cap
10. Scale mark 11, operation prompt mark 12, spongy cushion
Example 1A balloon gastric tube for use in the establishment of a model of the guinea pig for gastroesophageal reflux
Referring to fig. 1, fig. 1 is a schematic view of the overall structure of the present invention.
A sacculus stomach tube for establishing a gastroesophageal reflux animal model comprises a perfusion device, an inflation device, a marking device and a backflow prevention device, wherein the perfusion device comprises a perfusion tube 1 (shown in figure 3), a head end 101 of the perfusion tube, a middle section 102 of the perfusion tube, a tail end 103 of the perfusion tube and a perfusion opening 15, and the inflation device comprises an inflation tube 2 (shown in figure 3), a head end 201 of the inflation tube, a middle section 202 of the inflation tube, a tail end 203 of the inflation tube, an inflation sacculus 3, an air outlet 4 and an inflation opening 7; the identification device comprises a warning identification 6, a scale mark 10 and an operation prompt identification 11; the backflow prevention device comprises a plugging cap 9, a spongy cushion 12 (shown in figure 2) and a PH test paper 13 (shown in figure 2); the perfusion tube 1 is divided into three sections: the device comprises a head end 101 of a perfusion tube, a middle section 102 of the perfusion tube and a tail end 103 of the perfusion tube, wherein the head end 101 of the perfusion tube and the tail end 103 of the perfusion tube are in seamless fixed connection through the middle section 102 of the perfusion tube; the inflation tube 2 is divided into three sections: the air inflation pipe comprises an air inflation pipe head end 201, an air inflation pipe middle section 202 and an air inflation pipe tail end 203, wherein the air inflation pipe head end 201 and the air inflation pipe tail end 203 are in seamless fixed connection through the air inflation pipe middle section 202; the head end 101 of the perfusion tube is fixedly connected with the perfusion opening 15, the middle section 202 of the inflation tube and the tail end 203 of the inflation tube are fixedly connected and penetrate through the middle section 102 of the perfusion tube, the head end 201 of the inflation tube is fixedly connected with the inflation opening 7 in a seamless mode, the tail end 203 of the inflation tube is connected with the inflatable balloon 3, the tail end 203 of the inflation tube is provided with an air outlet 4, the outer surface of the middle section 102 of the perfusion tube is provided with an operation prompt mark 11 close to the end of the inflatable balloon 3, the end far away from the end of the inflatable balloon 3 is provided with a warning mark 6, a scale mark 10 is arranged between the warning mark 6 and the operation prompt mark 11, the head end 101 of the perfusion tube is fixedly connected with the perfusion opening 15, the perfusion opening 15 is detachably connected with a plugging cap 9, a sponge mat 12 and a PH test paper 13 are arranged in the perfusion; the balloon type gastric tube further comprises a traction guide wire 5 and a handle 8, one end of the traction guide wire 5 is fixedly connected with the handle 8, and the other end of the traction guide wire penetrates into the perfusion tube 1 from the perfusion opening 15 to the tail end 103 of the perfusion tube. Preferably, the total length of the balloon gastric tube is 20-40 cm. Preferably, the irrigation tube 1 has a diameter of 0.1-1.5 cm. Preferably, the inflatable balloon 3 has a diameter of 0.6-2.5 cm. Preferably, the number of the air outlet holes 4 is 1-5. Preferably, the warning mark 6 is a red mark, and the distance from the warning mark 6 to the inflatable balloon 3 is 5-10 cm. Preferably, the operation prompt mark 11 is a yellow mark, and the distance from the operation prompt mark 11 to the inflatable balloon 3 is 2-5 cm. Preferably, the balloon gastric tube is a single use balloon gastric tube. Preferably, the infusion tube 1 is made of a sterile, sterilized, elastomeric silicone material.
Referring to fig. 2, fig. 2 is a schematic structural diagram of the inside of the circle in fig. 1, i.e., a schematic structural diagram of the inside of the pouring opening.
The pouring port 15 is internally provided with a spongy cushion 12 and pH test paper 13, the pH test paper 13 is positioned on one side of the pouring port 15, which is close to the middle section 102 of the pouring pipe, and the spongy cushion 12 is positioned on one side of the pouring port 15, which is far away from the middle section 102 of the pouring pipe.
Referring to fig. 3, fig. 3 is a schematic cross-sectional structure diagram of the middle section of the perfusion tube and the middle section of the inflation tube.
The inflation tube 2 penetrates through the perfusion tube 1.
Referring to fig. 4, fig. 4 is a schematic view of a connection structure between the end of the inflation tube and the air outlet.
The tail end 203 of the inflation tube is provided with air outlets 4, and the number of the air outlets 4 is 1-5.
Referring to fig. 5, fig. 5 is a schematic structural view of the inflatable balloon when it is deflated in the use state.
The inflatable balloon 3 has a diameter similar to the diameter of the perfusion tube 1 in the deflated state.
Referring to fig. 6, fig. 6 is a schematic structural view of the inflatable balloon when inflated in a use state.
When the inflatable balloon 3 is inflated, the opening of the pipeline is fixed on the middle and lower segments of the esophagus of the animal, and the pipeline cannot be separated or displaced due to struggle of the animal, so that the perfusate (hydrochloric acid) can slowly flow into the pipeline, and mucous membranes of the middle and lower segments of the esophagus of the animal are stimulated to establish a gastroesophageal reflux model.
The utility model discloses a use method: when the device is used, firstly, the handle 8 is held by hand, the traction guide wire 5 is used in combination, the lower jaw of an animal is lifted under the prompt of the operation prompt mark 11 when the tail end 103 of the perfusion tube 1 is inserted into the stomach 14 of the animal from the respiration opening of the animal by 5-10cm, meanwhile, the inserted length of the gastric tube can be accurately determined in combination with the scale mark 10, the extending length of the gastric tube is rapidly determined in combination with the warning mark 6, after the gastric tube is inserted to the proper length, the inflation opening 7 is connected with the injector, gas enters the inflation balloon 3 through the inflation tube 2 and the air outlet 4, and the inflation balloon 3 is inflated; the perfusate is then injected into the animal's stomach 14 from the perfusion port 15 using a syringe containing the perfusate. When the perfusate is palirrhea when appearing, PH test paper 13 in the infusion mouth 15 can the colour development, and the palirrhea phenomenon of liquid appears in the suggestion operator, and simultaneously foam-rubber cushion 12 can absorb palirrhea liquid, and at this moment, the operator changes the perfusate. After the operation is finished, the injector connected with the inflation inlet 7 is used for pumping out the gas in the inflatable saccule 3, so that the inflatable saccule is in a contraction state, and the stomach tube is taken out of a driven object and discarded.
It should be noted that the distance between the connection starting end of the perfusion tube 1 and the inflation tube 2 and the inflation balloon 3 is the middle section 102 of the perfusion tube, and the other two ends of the perfusion tube 1 are respectively the head end 101 and the tail end 103 of the perfusion tube;
the distance between the connection starting end of the perfusion tube 1 and the inflation tube 2 and the operation prompt mark 11 is an inflation tube middle section 202, and the other two ends of the inflation tube 2 are respectively an inflation tube head end 201 and an inflation tube tail end 203.
The warning mark 6 is used for prompting the length of an intubation tube of an operator and helping the operator to quickly judge the insertion length of the gastric tube, and the operation prompting mark 11 is used for prompting the operator that when the gastric tube extends into 5-10cm from a respiration opening, the operator needs to raise the lower jaw of an animal so that the gastric tube can be smoothly inserted into the throat and enters the middle section of the animal stomach 14.
When the perfusion fluid is not required to be injected, the blocking cap 9 is covered above the perfusion opening 15.
When the animal perfusate is administered, the injector filled with the perfusate is inserted into the perfusion opening 15, so that the animal perfusate is administered, and the problem that the pH test paper 13 and the spongy cushion 12 preferentially and directly contact the perfusate (hydrochloric acid) when the perfusate (hydrochloric acid) is injected through the perfusion opening 15 in the molding process is solved.
The utility model provides a sacculus formula stomach tube is used to animal, simple structure, convenient to use ensures can not deviate from or shift because of struggling of animal at the molding in-process, and the unexpected death that the significantly reduced arouses the animal at the molding in-process improves the molding success rate of animal research, has very strong practicality.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and additions can be made without departing from the principles of the present invention, and these improvements and additions should also be regarded as the protection scope of the present invention.
Claims (8)
1. A sacculus stomach tube for establishing a gastroesophageal reflux animal model comprises a perfusion device, the perfusion device comprises a perfusion tube (1), a head end (101) of the perfusion tube, a middle section (102) of the perfusion tube, a tail end (103) of the perfusion tube and a perfusion opening (15), and is characterized in that the sacculus stomach tube further comprises an inflation device, an identification device and a backflow prevention device,
the inflation device comprises an inflation tube (2), a head end (201) of the inflation tube, a middle section (202) of the inflation tube, a tail end (203) of the inflation tube, an inflation balloon (3), an air outlet (4) and an inflation opening (7);
the identification device comprises a warning identification (6), scale marks (10) and an operation prompt identification (11);
the backflow prevention device comprises a plugging cap (9), a spongy cushion (12) and a PH test paper (13);
the perfusion tube (1) is divided into three sections: the device comprises a head end (101) of a perfusion tube, a middle section (102) of the perfusion tube and a tail end (103) of the perfusion tube, wherein the head end (101) of the perfusion tube and the tail end (103) of the perfusion tube are in seamless fixed connection through the middle section (102) of the perfusion tube; the inflation tube (2) is divided into three sections: the air inflation pipe comprises an air inflation pipe head end (201), an air inflation pipe middle section (202) and an air inflation pipe tail end (203), wherein the air inflation pipe head end (201) and the air inflation pipe tail end (203) are in seamless fixed connection through the air inflation pipe middle section (202);
the perfusion tube head end (101) is fixedly connected with a perfusion opening (15), the middle section (202) of the inflation tube and the tail end (203) of the inflation tube are fixedly connected and run through the middle section (102) of the perfusion tube, the head end (201) of the inflation tube is fixedly connected with an inflation opening (7) in a seamless manner, the tail end (203) of the inflation tube is connected with an inflation saccule (3), the tail end (203) of the inflation tube is provided with an air outlet (4), the outer surface of the middle section (102) of the perfusion tube is provided with an operation prompt mark (11) close to the end of the inflation saccule (3), the end far away from the inflation saccule (3) is provided with a warning mark (6), a scale mark (10) is arranged between the warning mark (6) and the operation prompt mark (11), the head end (101) of the perfusion tube is fixedly connected with the perfusion opening (15), the perfusion opening (15) is detachably connected with a plugging cap, the PH test paper (13) is positioned at one side of the perfusion opening (15) close to the middle section (102) of the perfusion tube, and the spongy cushion (12) is positioned at one side of the perfusion opening (15) far away from the middle section (102) of the perfusion tube;
the balloon type gastric tube further comprises a traction guide wire (5) and a handle (8), one end of the traction guide wire (5) is fixedly connected with the handle (8), and the other end of the traction guide wire penetrates into the perfusion tube (1) from the perfusion opening (15) to the tail end (103) of the perfusion tube.
2. A balloon gastric tube for use in establishing an animal model of gastroesophageal reflux according to claim 1, wherein the total length of the balloon gastric tube is 20-40 cm.
3. Balloon gastric tube for establishing an animal model of gastroesophageal reflux according to claim 1, characterised in that the diameter of the perfusion tube (1) is 0.1-1.5 cm.
4. The gastric tube of claim 1, wherein said inflatable balloon (3) has a diameter of 0.6-2.5 cm.
5. The balloon type gastric tube for establishing the animal model of gastroesophageal reflux according to claim 1, wherein the number of the air outlet holes (4) is 1-5.
6. The balloon gastric tube for creating an animal model of gastroesophageal reflux according to claim 1, wherein the warning mark (6) is a red mark, and the distance of the warning mark (6) from the inflated balloon (3) is 5-10 cm.
7. The balloon gastric tube for establishing the animal model of gastroesophageal reflux according to claim 1, wherein the operation indication mark (11) is a yellow mark, and the distance from the operation indication mark (11) to the inflatable balloon (3) is 2-5 cm.
8. A balloon gastric tube for use in establishing an animal model of gastroesophageal reflux according to claim 1, wherein the balloon gastric tube is a single use balloon gastric tube.
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| CN201920809459.4U CN210250853U (en) | 2019-05-31 | 2019-05-31 | Balloon type stomach tube for establishing gastroesophageal reflux animal model |
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| CN201920809459.4U CN210250853U (en) | 2019-05-31 | 2019-05-31 | Balloon type stomach tube for establishing gastroesophageal reflux animal model |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112617947A (en) * | 2020-12-24 | 2021-04-09 | 江苏省华星医疗器械实业有限公司 | Disposable three-cavity double-sac stomach tube |
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2019
- 2019-05-31 CN CN201920809459.4U patent/CN210250853U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112617947A (en) * | 2020-12-24 | 2021-04-09 | 江苏省华星医疗器械实业有限公司 | Disposable three-cavity double-sac stomach tube |
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