CN219184315U - Disease animal model alveolus lavage device with extensible placement plate - Google Patents

Abstract

The utility model relates to a disease animal model alveolar lavage device with an extensible placement plate, comprising: an injection base; the injection base is provided with a pushing structure for realizing an injection function, and a clamping structure is arranged in the pushing structure; the placing plate is arranged on one side corresponding to the output end of the pushing structure, and an extending structure for adjusting the placing area is arranged at the bottom of the placing plate; the placing plate is provided with a plurality of fixing components for fixing experimental animals.

Description

Disease animal model alveolus lavage device with extensible placement plate

Technical Field

The utility model belongs to the technical field of medical appliances, and particularly relates to a disease animal model alveolus lavage device with an extensible placement plate.

Background

At present, the alveolar lavage of a disease animal model is generally manually completed by experimental operators, the angle, speed and lavage amount of the alveolar lavage are not accurate enough, and errors can be caused by different experimental operators, such as the rupture of pulmonary alveolar walls caused by too fast operation during lavage, and the subsequent pathological observation of the lung and the measurement of cytokines and the like in the alveolar lavage liquid are influenced. In addition, under the condition that a large number of times of lavage are needed, the alveolar lavage operation takes too long, takes up labor and time, and influences the experimental progress; in addition, the model-building animals commonly used at present are various, and when the alveolus is perfused, the animal models cannot be well fixed, and the animal models of different types and different body types cannot be flexibly adjusted and fixed.

The present utility model addresses the above-described problems by providing a disease animal model alveolar lavage device with a malleable placement plate.

Disclosure of Invention

In order to overcome the problems presented in the background art, the present utility model provides an alveolar lavage device for a disease animal model with a malleable placement plate.

A disease animal model alveolar lavage device with malleable placement plate, comprising: an injection base; the injection base is provided with a pushing structure for realizing an injection function, and a clamping structure is arranged in the pushing structure; the placing plate is arranged on one side corresponding to the output end of the pushing structure, and an extending structure for adjusting the placing area is arranged at the bottom of the placing plate; the placing plate is provided with a plurality of fixing components for fixing experimental animals.

Further, a placing groove is formed in the top of the injection base, a first end of the placing groove is provided with an injector placing table, and a fixing structure for fixing the injector is arranged on the placing table; the second end of the placing groove is provided with a connecting table; a first limiting rod for limiting the pushing structure is arranged in the placing groove; this setting guarantees that the pushing structure has sufficient pushing space to through setting up the gag lever post one make pushing structure steady carry out the displacement.

Further, the pushing structure includes: ball screw, pushing assembly, motor; the ball screw is arranged in the placing groove, the pushing component is connected with the ball screw through a first connecting hole, and a first connecting hole connected with the first limiting rod is further formed in the pushing component; the output end of the motor is connected with the first end of the ball screw, and the motor drives the ball screw to rotate so as to realize the forward and backward movement of the pushing assembly.

Further, the motor is arranged in a motor cavity of the injector placing table, and the ball screw extends into the motor cavity through a first through hole arranged on the first end face of the motor cavity and is connected with the output end of the motor.

Further, the second end of the ball screw is provided with a bearing, so that friction force generated when the ball screw rotates is reduced.

Further, the pushing assembly includes: clamping structure and pushing block; the pushing block is internally provided with a first limit groove for fixing and limiting the clamping structure and a second limit groove for placing the injector, the first limit groove is communicated with the second limit groove through an opening groove, the clamping structure is arranged in the first limit groove, and the clamping part of the clamping structure extends out of the second limit groove and is used for clamping the injector.

Further, the top of the second limit groove is arranged in an open mode, and a placing opening for placing the pushing rod of the syringe is formed in the outer wall of the second limit groove.

Further, the placement port is an elastic opening structure, which comprises: a return spring I and a baffle; the two side walls of the placing opening are provided with spring grooves, the first end of the reset spring is fixedly arranged in the spring grooves, and the second end of the first reset spring is integrally connected with the baffle plate; the baffle includes: the first baffle and the second baffle are the same in size and shape, and are arranged in a mirror image mode; through the setting, the size of opening and closing the placing opening is flexibly adjusted according to the diameter of the injector push rod.

Further, the top of the first baffle plate is provided with an inclined plane I, the top of the second baffle plate is provided with an inclined plane II, and the inclined plane I and the inclined plane II are arranged in a mirror image mode; when the tail end of the injector push rod is placed in the second limiting groove, the first baffle plate and the second baffle plate are extruded to move towards two sides, so that flexible size adjustment according to the diameter of the injector push rod is realized.

Further, the clamping structure includes: the rotating wheel, the first threaded rod and the sliding block are adjusted; the adjusting rotating wheel is arranged in a connecting notch communicated with the first limiting groove; the first threaded rod is arranged in the first limit groove; the first threaded rod is provided with a thread section with opposite rotation directions; the slider includes: the first sliding block and the second sliding block; the first end face of the sliding block I and the first end face of the sliding block II are respectively provided with a rack I matched with the threaded section, and the second end face of the sliding block I and the second end face of the sliding block II are provided with annular bulges for clamping the injector; the sliding block I and the sliding block II can slide along the open slot; through the arrangement, the clamping of the tail sections of the injector push rods with different diameters of the first sliding block and the second sliding block is realized.

Further, the adjusting rotating wheel is provided with a first meshing tooth, the first threaded rod is provided with a middle section, the middle section is provided with a second meshing tooth, and the adjusting rotating wheel is rotated to drive the first threaded rod to rotate, so that the first sliding block and the second sliding block can move in a mirror image mode.

Further, through holes II are formed in the two short side faces of the first limiting groove, and the first end and the second end of the first threaded rod are connected and limited through the through holes II respectively.

Further, the placing table is provided with a fixing structure for fixing the syringe main body, and the fixing structure comprises: the second threaded rod, the second limiting rod, the fixing unit, the limiting unit and the locking unit; the second threaded rod is perpendicular to the top end face of the placing table and tangent to the short side end face of the placing table; the first end of the second limiting rod is connected with the injection base, and the second end of the second limiting rod and the highest point of the threaded rod are positioned on the same transverse plane; the second threaded rod is connected with the second limiting rod through a connecting body; the locking unit is connected with the first end of the second threaded rod, the fixing unit is connected with the second threaded rod and the second limiting rod, the fixing unit moves up and down along the second threaded rod and the second limiting rod, and the limiting unit is fixedly arranged on the top end surface of the placing table; through this setting realization to the fixed of syringe main part, can prevent to advance the slip of syringe main part in the in-process of injection to experimental animals, this setting can fix the syringe main part of different size diameters moreover.

Further, the limit unit includes: the first limiting unit and the second limiting unit are arranged in a mirror image mode by taking the center line of the placement opening as an axis.

Further, a lifting groove is formed in the first end face of the injection base, and a lifting shaft is arranged in the injection base; the bottom of the placing plate is provided with a lifting structure and is connected with a lifting shaft through the lifting structure; the height adjustment of the placing plate is realized by arranging the lifting groove and the lifting shaft.

Further, a second rack is arranged on the lifting shaft and is integrally connected with the lifting shaft, and the second rack is parallel to the lifting groove and opposite to the lifting groove.

Further, the lifting structure includes: lifting assembly, worm wheel, worm, transmission handle; the lifting assembly is sleeved on the lifting shaft, the turbine is arranged in the lifting assembly, and the fixed shaft is arranged in the lifting assembly for positioning and fixing; the worm is arranged above the worm wheel, and the transverse sectional lines of the worm wheel and the worm are in the same plane and are parallel to each other; the transmission handle is arranged at the first end of the worm, and the worm is driven to rotate by rotating the transmission handle, so that the lifting structure moves up and down along the lifting shaft, and the height of the placing plate is adjusted.

Further, the lifting assembly includes: the lifting device comprises a lantern ring sleeved with a lifting shaft, a first partition plate and a second partition plate, wherein the first partition plate and the second partition plate are connected with the lantern ring, a space is reserved between the first partition plate and the second partition plate, the space width is identical to the width of a worm wheel, and the worm wheel is guaranteed to be contacted with a rack arranged on the lifting shaft through the arrangement.

Further, a first fixed block and a second fixed block are arranged at the tops of the first partition plate and the second partition plate, a first through hole is formed in the first fixed block, a second through hole is formed in the second fixed block, and the distance between the first fixed block and the second fixed block is the same as the length of a threaded section of the worm.

Further, a first extending shaft is arranged at the first end of the worm, a second extending shaft is arranged at the second end of the worm, the first extending shaft is connected with the first penetrating hole, and the second extending shaft is connected with the second penetrating hole; through this structure, realize the spacing to the worm.

Further, the first extension shaft is provided with an extension section, and the transmission handle is connected with the extension end; through the arrangement, the transmission handle drives the worm to rotate.

Further, a support frame is arranged at the tops of the first partition plate and the second partition plate, a sliding rail is arranged on the support frame, and a sliding platform is arranged to be connected with the sliding rail; the bottom of the placing plate is provided with a sliding frame which is connected with the sliding platform; and realize translating along the slide rail through sliding platform to this lateral shifting who places the board is realized, is convenient for the experimenter through this setting to carry out operations such as trachea cannula, alveolus lavage and dissection to experimental animals.

Further, a first connecting shaft is arranged on the sliding platform, and the inside of the first connecting shaft is hollow; the bottom of the sliding frame is provided with a second connecting shaft, and the first connecting shaft is sleeved with the second connecting shaft; the placement plate is arranged to rotate by the circle center of the first connecting shaft and the second connecting shaft; the experimental personnel can conveniently carry out various experimental operations on experimental animals.

Further, locking bolts are arranged on two sides of the sliding rail, and the position of the placing plate after being transversely moved is fixed through the locking bolts.

Further, the placement plate includes: a main placing plate, a secondary placing plate I and a secondary placing plate II; the main board bottom of placing is provided with the extension structure, and vice board one of placing and vice board two pass through the extension structure realization and the main combination of placing the board to the adjustment to placing the board area size is realized through the extension structure.

Further, the extension structure includes: the device comprises a threaded rod III, a rocker I, a rocker II, an extension assembly, a travel rod I and a travel rod II; the third threaded rod is connected with the sliding frame; the extension assembly is connected with the threaded rod III and moves along the threaded rod III; the first end of the rocker I and the first end of the rocker II are hinged with two sides of the extension assembly respectively, the second end of the rocker I is hinged with a travel block I at the bottom of the auxiliary placing plate I, and the second end of the rocker II is hinged with a travel block II at the bottom of the auxiliary placing plate II; the first auxiliary placing plate is in sliding connection with the first travel rod through the first travel block, and the second auxiliary placing plate is in sliding connection with the second travel rod through the second travel block; when the threaded rod III rotates, the extension assembly moves forwards or backwards along the threaded rod III, and the rocker I and the rocker II drive the auxiliary placing plate I and the auxiliary placing plate II to slide along the travel rod I and the travel rod II while the extension assembly moves.

Further, the first stroke rod and the second stroke rod are respectively arranged at the left side and the right side of the third threaded rod, and the first ends of the first stroke rod and the second stroke rod are integrally connected with the first end of the third threaded rod; an included angle of 35-65 degrees exists between the first stroke rod, the second stroke rod and the third threaded rod; through the arrangement, the first auxiliary placing plate and the second auxiliary placing plate can stably extend outwards along the first travel rod and the second travel rod.

Further, the fixing assembly includes: the fixing assembly I, the fixing assembly II and the fixing assembly III are arranged on the main placing plate, the fixing assembly II is arranged on the auxiliary placing plate I, and the fixing assembly III is arranged on the auxiliary placing plate II; the first fixing component, the second fixing component and the third fixing component have the same composition structure; the first fixing component is used for fixing the forelimbs of the experimental animals, and the second fixing component and the third fixing component are used for fixing the hind limbs of the experimental animals; through the arrangement, the experimental animals of different types and different body types are fixed.

Further, the main placing plate is also provided with an elastic fixing belt for fixing the trunk part of the experimental animal.

Further, two sliding grooves are formed in the main placing plate in a mirror image mode, and a first fixing assembly is arranged in each sliding groove; the two fixing assemblies can do translational movement along the sliding groove; through this setting can be nimble the interval between two fixed subassembly ones of regulation to realize the fixed to different kind and different body types experimental animal forelimbs.

Further, the second fixing component is fixedly arranged on the first auxiliary placing plate, the third fixing component is fixedly arranged on the second auxiliary placing plate, and the distance between the second fixing component and the third fixing component is adjusted by extending operation between the first auxiliary placing plate and the second auxiliary placing plate.

Further, the first fixing component comprises: the fixed claw, the rectangular body, the rocker III and the reset spring II; an operation cavity is arranged in the fixing component; the rectangular body is arranged in the operation cavity in a sliding manner; the second reset spring is arranged at the bottom of the rectangular body, and the fixed claw is fixedly connected to the first end face of the rectangular body; the outer wall of the rectangular body is provided with a travel groove; the third first end of the rocker is connected with a protruding shaft in the operation cavity, and the third second end of the rocker is provided with a connecting protrusion; the connecting protrusion moves along the travel groove; when the fixed claw is pressed down, the rectangular body slides downwards, and the reset spring II is pressed down, so that the fixed claw is clamped; and when the fixed claw is pressed down again, the second return spring returns, and the fixed claw releases the clamping.

Further, the fixed claw is made of elastic materials, and the maximum diameter of the fixed claw is larger than that of the operation cavity; when the fixed claw enters the operation cavity, the fixed claw is blocked by the operation cavity to clamp the forelimbs of the experimental animal.

Further, the travel groove is provided with a first concave point and a second concave point, the fixing claw is in a release state when the connecting protrusion is located in the first concave point, and the fixing claw is in a clamping state when the connecting protrusion is located in the second concave point.

Further, the control structure is disposed within the injection base, the control structure comprising: the device comprises an operation panel, a central control module and a frequency conversion module; the central control module is used for receiving input signals and controlling the pushing and back-drawing travel distance of the pushing assembly; the operation panel is connected with the central control module and used for inputting operation instructions, the frequency conversion module is connected with the central control module, and the frequency conversion module is connected with the motor line; the output power of the motor is controlled through the frequency conversion module, and meanwhile, the forward and reverse rotation of the motor is controlled through the central control module, so that the injection and the back suction of the injector are driven.

Further, the operation panel includes: a display screen and operation keys; the operation key includes: a power key, a number key, a motor speed-down key, a motor speed-up key, a pause key, and a bolus mode setting key; the push injection and back pumping speed and the push injection and back pumping times are accurately regulated and controlled through the setting; meanwhile, the display screen can display the input information, so that the experimenter can read the information conveniently.

Further, still be provided with power supply unit in the injection base, injection base outer wall is provided with the power wiring, realizes supplying power to control structure through this setting.

When the fixing device is used, firstly, an anesthetized experimental animal is fixed on a main placing plate through an elastic fixing belt, and four limbs of the experimental animal are fixed through a fixing component I, a fixing component II and a fixing component III; adjusting the position of the experimental animal to a proper position for alveolar lavage by using a lifting structure; the injector is fixed through a fixing structure, and the tail section of the push rod of the injector is fixed in the pushing assembly through a clamping structure; after the preparation, the pushing speed and the drawing speed are set through the control structure, and the stroke length of the pushing assembly is set through the control structure; in addition, the number of times of advancement and retraction can be set by the control structure.

The utility model has the beneficial effects that: (1) By arranging the control structure and the pushing component, the speed and the lavage quantity of the alveoli can be accurately controlled, and errors caused by operation differences are reduced; (2) Through setting up elevation structure and have fixed assembly place the board, realize fixing the experimental animal of different sizes, and can be according to the adjustment of the height when the body type of experimental animal carries out the injection; (3) Reduces the time and labor of alveolar lavage operation and accelerates the progress of experiments.

Drawings

FIG. 1 is a schematic diagram of the overall structure of the present utility model;

FIG. 2 is a schematic front view of the present utility model;

FIG. 3 is a left side schematic view of the present utility model;

FIG. 4 is an internal cross-sectional view of the present utility model;

FIG. 5 is a schematic diagram of a pushing assembly according to the present utility model;

FIG. 6 is a schematic cross-sectional view of a push assembly of the present utility model;

FIG. 7 is a schematic top cross-sectional view of the push assembly of the present utility model;

FIG. 8 is a schematic view of a fastening structure according to the present utility model;

FIG. 9 is a schematic view of a placement stage according to the present utility model;

FIG. 10 is a schematic cross-sectional view of a lifting structure of the present utility model;

FIG. 11 is a schematic cross-sectional view of a lift assembly of the present utility model;

FIG. 12 is a schematic view of a track according to the present utility model;

FIG. 13 is a schematic top view of the placement stage of the present utility model;

FIG. 14 is a schematic view of the bottom of the inventive placement stage;

FIG. 15 is a schematic view of a fastening assembly according to the present utility model;

FIG. 16 is an internal cross-sectional view of a securing assembly according to the present utility model;

in the figure, 1, an injection base; 11. a placement groove; 111. a placement table; 1111. a motor cavity; 112. a connection station; 113. a first limit rod; 12. a ball screw; 13. a pushing assembly; 131. a pushing block; 132. a first limit groove; 133. a limiting groove II; 134. a placement port; 135. adjusting the rotating wheel; 136. a first threaded rod; 137. a first sliding block; 138. a second sliding block; 139. an annular protrusion; 14. a motor; 15. a second threaded rod; 151. a second limiting rod; 152. a fixing unit; 153. a first limiting unit; 1531. a second limiting unit; 154. a locking unit; 155. a connecting body; 2. a lifting groove; 21. a lifting shaft; 22. a second rack; 23. a lifting assembly; 24. a worm wheel; 25. a worm; 26. a transmission handle; 27. a fixed shaft; 28. a first fixed block; 29. a second fixed block; 291. a first partition board; 292. a second partition board; 3. a support frame; 31. a slide rail; 311. a locking bolt; 32. a carriage; 33. a sliding platform; 34. a first connecting shaft; 4. a main placement plate; 41. a first auxiliary placing plate; 42. a second auxiliary placing plate; 43. a third threaded rod; 44. a rocker I; 45. a rocker II; 46. an extension assembly; 47. a travel bar I; 48. a travel bar II; 5. a first fixing component; 51. a fixed claw; 511. a rectangular body; 512. a rocker III; 513. a second reset spring; 52. a second fixing component; 53. a fixing component III; 54. an elastic fixing band; 56. a sliding groove; 561. a first pit; 562. a second pit; 6. a display screen; 61. an operation key; 62. a central control module; 63. a frequency conversion module; 64. a power supply device; 65. and (5) connecting a power supply.

Detailed Description

The following detailed description of the embodiments of the present utility model will be made more apparent to those skilled in the art from the following detailed description, in which the utility model is embodied in several, but not all, embodiments of the utility model. The utility model may be embodied or applied in other specific forms and features of the following examples and examples may be combined with each other without conflict, all other examples being contemplated by those of ordinary skill in the art without undue burden from the present disclosure, based on the examples of the utility model.

Example 1

Referring to fig. 1-4, an alveolar lavage device for a disease animal model with a malleable placement plate includes an injection base 1; an injection structure is arranged on the injection base 1; the injection structure comprises: a control structure for controlling injection frequency and a pushing structure for realizing injection function; the pushing structure is internally provided with a clamping structure capable of clamping syringes with different sizes, and a control structure is used for controlling the pushing structure to complete the suction operation; a placing plate for placing experimental animals is additionally arranged; the placing plate is provided with an extension structure for adjusting the placing area; the placing plate is provided with a lifting structure for adjusting the height of the placing table 111; the placing plate is connected with the injection base 1 through a lifting structure; the placing plate is provided with a fixing component for fixing experimental animals.

A control structure is provided within the injection base 1, said control structure comprising: an operation panel, a central control module 62 and a frequency conversion module 63; the central control module 62 is used for receiving input signals and controlling the pushing and back-drawing travel distance of the pushing assembly 13; the operation panel is connected with the central control module 62 and is used for inputting operation instructions, the frequency conversion module 63 is connected with the central control module 62, and the frequency conversion module 63 is connected with the motor 14 in a line way; the output power of the motor 14 is controlled by the frequency conversion module 63, and meanwhile, the forward and reverse rotation of the motor 14 is controlled by the central control module 62, so that the injection and the withdrawal of the injector are driven.

The operation panel includes: a display 6 and operation keys 61; the operation key 61 includes: a power key, a number key, a motor 14 deceleration key, a motor 14 acceleration key, a pause key, and a bolus mode setting key; the push injection and back pumping speed and the push injection and back pumping times are accurately regulated and controlled through the setting; meanwhile, the display screen 6 can display the input information, so that the experimenter can read the information conveniently.

The injection base 1 is also provided with a power supply device 64, the outer wall of the injection base 1 is provided with a power supply wiring 65, and the control structure is powered by the arrangement.

Example 2

Referring to fig. 1 to 4, the injection base 1 and the pushing structure are set on the basis of embodiment 1, the injection base 1 is provided with a placement groove 11 at the top, a first end of the placement groove 11 is provided with a syringe placement table 111, and a second end of the placement groove 11 is provided with a connection table 112; a first limiting rod 113 for limiting the pushing structure is arranged in the placing groove 11; this arrangement ensures that the pushing structure has sufficient pushing space and enables stable displacement of the pushing structure by providing the first limit lever 113.

The pushing structure comprises: a ball screw 12, a pushing assembly 13, and a motor 14; the ball screw 12 is arranged in the placing groove 11, the pushing component 13 is connected with the ball screw 12 through a first connecting hole, and the pushing component 13 is also provided with a first connecting hole connected with a first limiting rod 113; the output end of the motor 14 is connected with the first end of the ball screw, and the motor 14 drives the ball screw 12 to rotate so as to realize the forward and backward movement of the pushing assembly 13.

The motor 14 is disposed in the motor chamber 1111 of the syringe placement stage 111, and the ball screw is inserted into the motor chamber 1111 through a first through hole provided in a first end surface of the motor chamber 1111 and connected to an output end of the motor 14.

The second end of the ball screw 12 is provided with a bearing to reduce friction when the ball screw 12 rotates.

Example 3

Referring to fig. 1 to 7, the pushing assembly 13 is provided on the basis of embodiment 2, and the pushing assembly 13 includes: a clamping structure, a pushing block 131; the pushing block 131 is internally provided with a first limiting groove 132 for fixing and limiting a clamping structure and a second limiting groove 133 for placing the syringe, the first limiting groove 132 is communicated with the second limiting groove 133 through an opening groove, the clamping structure is arranged in the first limiting groove 132, and the clamping part of the clamping structure extends out of the second limiting groove 133 and is used for clamping the syringe.

The top of the second limiting groove 133 is provided with an opening, and the outer wall of the second limiting groove 133 is provided with a placing opening 134 for placing the syringe push rod.

The placement port 134 is a flexible opening structure comprising: a return spring I and a baffle; the two side walls of the placing opening 134 are provided with spring grooves, the first end of the reset spring is fixedly arranged in the spring grooves, and the second end of the first reset spring is integrally connected with the baffle plate; the baffle includes: the first baffle and the second baffle are the same in size and shape, and are arranged in a mirror image mode; the size of opening and closing the placement port 134 by this arrangement is flexibly adjusted according to the diameter of the syringe plunger.

The top of the baffle I is provided with an inclined plane I, the top of the baffle II is provided with an inclined plane II, and the inclined plane I and the inclined plane II are arranged in a mirror image mode; when the tail end of the injector push rod is placed in the limit groove II 133, the baffle I and the baffle II are extruded to move towards two sides, so that flexible size adjustment according to the diameter of the injector push rod is realized.

The clamping structure comprises: the rotating wheel 135, the first threaded rod 136 and the sliding block are adjusted; the adjusting rotating wheel 135 is arranged in a connecting notch communicated with the first limiting groove 132; the first threaded rod 136 is disposed in the first limit groove 132; and the first threaded rod 136 is provided with thread segments of opposite directions; the slider includes: a first slide 137 and a second slide 138; the first end surfaces of the first slide block 137 and the second slide block 138 are respectively provided with a first rack matched with the threaded section, and the second end surfaces of the first slide block 137 and the second slide block 138 are provided with annular protrusions 139 for clamping the injector; the first slide block 137 and the second slide block 138 can slide along the open slot; by the arrangement, the clamping of the sliding block one 137 and the sliding block two 138 on the tail sections of the push rods of the syringes with different diameters is realized.

The adjusting rotating wheel 135 is provided with a first engaging tooth, the first threaded rod 136 is provided with a middle section, the middle section is provided with a second engaging tooth, and the adjusting rotating wheel 135 is rotated to drive the first threaded rod 136 to rotate, so that the first sliding block 137 and the second sliding block 138 can move in a mirror image mode.

Two short side surfaces of the first limiting groove 132 are respectively provided with a second through hole, and the first end and the second end of the first threaded rod 136 are respectively connected and limited through the second through holes.

Example 4

Referring to fig. 8, a fixing structure is provided on the basis of embodiment 1, and a fixing structure for fixing a syringe body is provided on a placement stage 111, the fixing structure including: the second threaded rod 15, the second limiting rod 151, the fixing unit 152, the limiting unit and the locking unit 154; the second threaded rod 15 is perpendicular to the top end surface of the placing table 111 and tangent to the short side end surface of the placing table 111; the first end of the second limiting rod 151 is connected with the injection base 1, and the second end of the second limiting rod 151 and the highest point of the second threaded rod 15 are positioned on the same transverse plane; the second threaded rod 15 is connected with the second limiting rod 151 through a connecting body 155; the locking unit 154 is connected with the first end of the second threaded rod 15, the fixing unit 152 is connected with the second threaded rod 15 and the second limiting rod 151, the fixing unit 152 moves up and down along the second threaded rod 15 and the second limiting rod 151, and the limiting unit is fixedly arranged on the top end surface of the placing table 111; through this setting realization to the fixed of syringe main part, can prevent to advance the slip of syringe main part in the in-process of injection to experimental animals, this setting can fix the syringe main part of different size diameters moreover.

The limit unit includes: the first limiting unit 153 and the second limiting unit 1531 are disposed in a mirror image manner with the center line of the placement opening 134 as an axis.

Example 5

Referring to fig. 9 to 12, the lifting structure is provided on the basis of embodiment 1, the lifting groove 2 is provided at the first end surface of the injection base 1, and the lifting shaft 21 is provided inside the injection base 1; the bottom of the placing plate is provided with a lifting structure and is connected with a lifting shaft 21 through the lifting structure; the height adjustment of the placing plate is realized by arranging the lifting groove 2 and the lifting shaft 21.

The lifting shaft 21 is provided with a second rack 22, the second rack 22 is integrally connected with the lifting shaft 21, the second rack 22 is parallel to the lifting groove 2, and the second rack 22 is opposite to the lifting groove 2.

The lifting structure comprises: the lifting assembly 23, the worm wheel 24, the worm 25 and the transmission handle 26; the lifting assembly 23 is sleeved on the lifting shaft 21, the turbine is arranged in the lifting assembly 23, and a fixed shaft 27 is arranged in the lifting assembly 23 for positioning and fixing; the worm 25 is arranged above the worm wheel 24, and the cross sections of the worm wheel 24 and the worm 25 are in the same plane and are parallel to each other; the transmission handle 26 is arranged at the first end of the worm 25, and the worm 25 is driven to rotate by rotating the transmission handle 26, so that the lifting structure moves up and down along the lifting shaft 21, and the height of the placing plate is adjusted.

The elevating assembly 23 includes: the sleeve ring sleeved with the lifting shaft 21 is provided with a first partition plate 291 and a second partition plate 292 which are connected with the sleeve ring, a space is reserved between the first partition plate 291 and the second partition plate 292, the space width is the same as the width of the worm wheel 24, and the worm wheel 24 is ensured to be contacted with a rack arranged on the lifting shaft 21 through the arrangement.

The tops of the first 291 and the second 292 partition plates are provided with a first 28 and a second 29 fixed block, the first 28 fixed block is provided with a first through hole, the second 29 fixed block is provided with a second through hole, and the distance between the first 28 fixed block and the second 29 fixed block is the same as the length of the thread section of the worm 25.

The first end of the worm 25 is provided with a first extending shaft, the second end of the worm 25 is provided with a second extending shaft, the first extending shaft is connected with the first penetrating hole, and the second extending shaft is connected with the second penetrating hole; by this structure, the limit of the worm 25 is achieved.

The first extension shaft is provided with an extension section, and the transmission handle 26 is connected with the extension end; by this arrangement, the drive handle 26 drives the worm 25 to rotate.

The tops of the first partition plate 291 and the second partition plate 292 are provided with a support frame 3, the support frame 3 is provided with a sliding rail 31, and a sliding platform 33 is arranged to be connected with the sliding rail 31; the bottom of the placing plate is provided with a sliding frame 32, and the sliding frame 32 is connected with a sliding platform 33; and the sliding platform 33 is used for realizing translation along the sliding rail 31, so that the transverse movement of the placing plate is realized, and the device is convenient for experimental personnel to perform operations such as trachea cannula, alveolus lavage, dissection and the like on experimental animals.

The experimental animal sliding platform 33 is provided with a first connecting shaft 34, and the inside of the first connecting shaft 34 is hollow; the bottom of the sliding frame 32 is provided with a second connecting shaft 34 which is sleeved with the second connecting shaft; the placement plate is rotated by the circle center of the first connecting shaft 34 and the second connecting shaft through the arrangement; the experimental personnel can conveniently carry out various experimental operations on experimental animals.

The slide rail 31 is provided with a lock bolt 311, and the position of the placing plate after the lateral movement is fixed by the lock bolt 311.

Example 6

Referring to fig. 13 to 14, setting the placement board on the basis of embodiment 5 includes: a main placing plate 4, a first auxiliary placing plate 41 and a second auxiliary placing plate 42; the bottom of the main placing plate 4 is provided with an extension structure, the first auxiliary placing plate 41 and the second auxiliary placing plate 42 are combined with the main placing plate 4 through the extension structure, and the size of the area of the placing plate is adjusted through the extension structure.

The extension structure includes: a third threaded rod 43, a first rocker 44, a second rocker 45, an extension assembly 46, a first travel rod 47 and a second travel rod 48; the third threaded rod 43 is connected with the sliding frame 32; the extension assembly 46 is connected with the third threaded rod 43, and the extension assembly 46 moves along the third threaded rod 43; the first ends of the rocker one 44 and the rocker two 45 are respectively hinged with two sides of the extension assembly 46, the second end of the rocker one 44 is hinged with a first stroke block at the bottom of the auxiliary placing plate one 41, and the second end of the rocker two 45 is hinged with a second stroke block at the bottom of the auxiliary placing plate two 42; the first auxiliary placing plate 41 is in sliding connection with the first stroke rod 47 through the first stroke block, and the second auxiliary placing plate 42 is in sliding connection with the second stroke rod 48 through the second stroke block; when the third threaded rod 43 rotates, the extension assembly moves forward or backward along the third threaded rod 43, and the first and second auxiliary placing plates 41 and 42 are driven to slide along the first and second travel rods 47 and 48 by the first and second rockers 44 and 45 while the extension assembly moves.

The first stroke rod 47 and the second stroke rod 48 are respectively arranged at the left side and the right side of the third threaded rod 43, and the first ends of the first stroke rod 47 and the second stroke rod 48 are integrally connected with the first end of the third threaded rod 43; and an included angle of 35-65 degrees exists between the first stroke rod 47, the second stroke rod 48 and the third threaded rod 43; by the arrangement, the first auxiliary placing plate 41 and the second auxiliary placing plate 42 can extend outwards along the first travel rod 47 and the second travel rod 48 smoothly.

Example 7

Referring to fig. 13 to 16, a fixing assembly is provided on the basis of embodiment 6, the fixing assembly comprising: the fixing device comprises a first fixing component 5, a second fixing component 52 and a third fixing component 53, wherein the first fixing component 5 is arranged on a main placing plate 4, the second fixing component 52 is arranged on a first auxiliary placing plate 41, and the third fixing component 53 is arranged on a second auxiliary placing plate 42; the first fixing component 5, the second fixing component 52 and the third fixing component 53 have the same composition structure; the first fixing component 5 is used for fixing the forelimbs of the experimental animals, and the second fixing component 52 and the third fixing component 53 are used for fixing the hindlimbs of the experimental animals; through the arrangement, the experimental animals of different types and different body types are fixed.

The main placing plate 4 is also provided with an elastic fixing belt 54 for fixing the trunk part of the experimental animal.

Two sliding grooves 56 are arranged on the main placing plate 4 in a mirror image mode, and a first fixing component 5 is arranged in each of the two sliding grooves 56; both fixing assemblies one 5 can perform translational movement along the sliding groove 56; through this setting can be nimble the interval between two fixed subassembly one 5 of regulation to realize the fixed to different kind and different body types experimental animal forelimbs.

The second fixing component 52 is fixedly arranged on the first auxiliary placing plate 41, the third fixing component 53 is fixedly arranged on the second auxiliary placing plate 42, and the distance between the second fixing component 52 and the third fixing component 53 is adjusted by extending the first auxiliary placing plate 41 and the second auxiliary placing plate 42.

The first fixing assembly 5 includes: the fixed claw 51, the rectangular body 511, the rocker III 512 and the return spring II 513; an operation cavity is arranged in the fixing component; the rectangular body 511 is slidably arranged in the operation cavity; the second return spring 513 is disposed at the bottom of the rectangular body 511, and the fixing claw 51 is fixedly connected to the first end surface of the rectangular body 511; the outer wall of the rectangular body 511 is provided with a travel groove; the first end of the rocker III 512 is connected with a protruding shaft in the operation cavity, and the second end of the rocker III 512 is provided with a connecting protrusion; the connecting protrusion moves along the travel groove; when the fixed claw 51 is pressed down, the rectangular body 511 slides downwards, and simultaneously the return spring II 513 is pressed down, so that the fixed claw 51 is clamped; when the fixing claw 51 is pressed down again, the second return spring 513 returns, and the fixing claw 51 releases the clamping.

The fixed jaw 51 is made of elastic material, and the maximum diameter of the fixed jaw 51 is larger than the maximum diameter of the operation cavity; when the fixed claw 51 enters the operation cavity, the fixed claw 51 is blocked by the operation cavity to clamp the forelimbs of the experimental animal.

The stroke groove is provided with a first concave point 561 and a second concave point 562, the fixing pawl 51 is in a released state when the connection protrusion is located at the first concave point 561, and the fixing pawl 51 is in a clamped state when the connection protrusion is located at the second concave point 562.

The above description of embodiments is only for the understanding of the present utility model. It should be noted that it will be apparent to those skilled in the art that modifications can be made to the present utility model without departing from the principles of the utility model, and such modifications will fall within the scope of the claims.

Claims (10)

1. An alveolar lavage device for a disease animal model with a malleable placement plate, comprising, an injection base; the injection device is characterized in that an injection function pushing structure is arranged on the injection base, and a clamping structure is arranged in the pushing structure; the placing plate is arranged on one side corresponding to the output end of the pushing structure, and an extending structure for adjusting the placing area is arranged at the bottom of the placing plate; the placing plate is provided with a plurality of fixing components for fixing experimental animals.

2. The disease animal model alveolar lavage device with malleable placement plate of claim 1, wherein the placement plate comprises: a main placing plate, a secondary placing plate I and a secondary placing plate II; the bottom of the main placing plate is provided with an extension structure, and the first auxiliary placing plate and the second auxiliary placing plate are combined with the main placing plate through the extension structure.

3. The disease animal model alveolar lavage device with malleable placement plate of claim 2, wherein the malleable structure comprises: the device comprises a threaded rod III, a rocker I, a rocker II, an extension assembly, a travel rod I and a travel rod II; the third threaded rod is connected with the sliding frame; the extension assembly is connected with the threaded rod III and moves along the threaded rod III; the first end of the rocker I and the first end of the rocker II are hinged with two sides of the extension assembly respectively, the second end of the rocker I is hinged with a travel block I at the bottom of the auxiliary placing plate I, and the second end of the rocker II is hinged with a travel block II at the bottom of the auxiliary placing plate II; the first auxiliary placing plate is in sliding connection with the first travel rod through the first travel block, and the second auxiliary placing plate is in sliding connection with the second travel rod through the second travel block.

4. The disease animal model alveolar lavage device with the extensible placement plate according to claim 3, wherein the first stroke rod and the second stroke rod are respectively arranged at the left side and the right side of the third threaded rod, and the first ends of the first stroke rod and the second stroke rod are integrally connected with the first end of the third threaded rod; and an included angle of 35-65 degrees exists between the first stroke rod, the second stroke rod and the third threaded rod.

5. The disease animal model alveolar lavage device with malleable placement plate of claim 1 wherein the fixation assembly comprises: the fixing assembly I, the fixing assembly II and the fixing assembly III are arranged on the main placing plate, the fixing assembly II is arranged on the auxiliary placing plate I, and the fixing assembly III is arranged on the auxiliary placing plate II; the first fixing component, the second fixing component and the third fixing component have the same composition structure; the first fixing component is used for fixing the forelimbs of the experimental animals, and the second fixing component and the third fixing component are used for fixing the hindlimbs of the experimental animals.

6. The disease animal model alveolar lavage device with the extensible placement plate according to claim 2, wherein two sliding grooves are mirror-image arranged on the main placement plate, and a first fixing component is arranged in each sliding groove; both fixing components can move in a translational manner along the sliding groove.

7. The disease animal model alveolar lavage device with extensible placement plate of claim 5 wherein the second fixation assembly is fixedly disposed on the first secondary placement plate and the third fixation assembly is fixedly disposed on the second secondary placement plate.

8. The disease animal model alveolar lavage device with malleable placement plate of claim 5 wherein the fixation assembly one comprises: the fixed claw, the rectangular body, the rocker III and the reset spring II; an operation cavity is arranged in the fixing component; the rectangular body is arranged in the operation cavity in a sliding manner; the second reset spring is arranged at the bottom of the rectangular body, and the fixed claw is fixedly connected to the first end face of the rectangular body; the outer wall of the rectangular body is provided with a travel groove; the third first end of the rocker is connected with a protruding shaft in the operation cavity, and the third second end of the rocker is provided with a connecting protrusion; the connection protrusion moves along the travel groove.

9. The disease animal model alveolar lavage device with malleable placement plate of claim 8 wherein the fixation pawl is made of an elastic material and the maximum diameter of the fixation pawl is greater than the maximum diameter of the operating chamber.

10. The disease animal model alveolar lavage device with malleable placement plate of claim 8 wherein the stroking groove is provided with a first concavity and a second concavity.

Images