CN219117449U - Separating device for layered liquid - Google Patents

Abstract

The utility model relates to the technical field of medical equipment, and provides a separating device for layered liquid, which comprises a device main body, a recognition chamber arranged on the device main body, a first separating tube and a second separating tube which are detachably connected with the recognition chamber and are mutually communicated, a moving mechanism which is connected with the first separating tube and is used for pushing the first separating tube to lead out the internal layered liquid to the second separating tube, a recognition module which is arranged in the recognition chamber and is used for recognizing the layering condition of the layered liquid, and a central processor which is respectively connected with the recognition module and the moving mechanism. The utility model aims to solve the problems of large fluctuation of manual extraction concentration and unstable extraction quality when the layered liquid separation is performed manually. The utility model realizes the standardization of the separation process, improves the quality of the separated liquid layer, reduces the labor input of the layered liquid in the liquid layer separation and extraction process, and improves the preparation efficiency.

Description

Separating device for layered liquid

Technical Field

The utility model relates to the technical field of medical instruments, in particular to a separating device for layered liquid.

Background

In clinical applications, a certain component in the liquid is often required to be extracted, for example, blood contains erythrocytes, leukocytes, platelets and the like, platelets rich in Growth factors (Growth factor) in the blood are particularly effective for various healing, platelet liquid layers are clinically required to be separated and extracted, and regeneration factors of the platelet liquid layers can provide various Growth factors, promote organism repair, promote wound closure, stimulate tissue regeneration and enhance local anti-infective capability, and the regeneration factors are commonly existing in the blood, but have low concentration, unobvious therapeutic effect and have excellent therapeutic effect only after the enriched high concentration regeneration factors. For example, a concentrated component containing an exosome solution can be used for in vitro diagnosis, detection, or concentration treatment, and liquid layer separation and extraction are also needed.

At present, in order to extract a certain component in blood, cell suspension, exosome-containing solution and other liquids, the operation of separating and extracting is complicated and the operation time is long. For example, in a conventional blood separation device for extracting platelet-rich growth factors, centrifugal separation is mainly performed in a housing space formed in a lower portion of a main body tube, white blood cells of a separation layer of blood after centrifugal separation are injected into a separation space portion of the main body tube, and then concentrated platelets can be collected and extracted by connecting an upper cover design to a passage portion of the main body tube, whereby separation of blood and extraction of concentrated platelets can be performed, loss during transfer can be prevented, and working time can be shortened.

However, the separation process of the scheme still needs to be manually performed for intervention extraction and collection operation, the preparation is affected by various factors through manual operation, the fluctuation of the separation concentration of the layered liquid layer is large, in the separation process, the manual operation has no specific and uniform separation standard, the fluctuation of the quality of the same batch of products is large finally, the fluctuation of the concentration multiple between the same batch of individuals is large easily, and the final treatment effect of the extracted liquid layer is affected.

Disclosure of Invention

The utility model aims to overcome the defects of large fluctuation of extraction concentration and unstable extraction quality when the layered liquid separation is carried out manually, and provides a separation device for the layered liquid. The utility model realizes the standardization of the separation process, improves the quality of the separated liquid layer, reduces the intervention of manual operation and improves the overall efficiency of the separation preparation process.

In order to solve the technical problems, the utility model adopts the following technical scheme:

the utility model provides a separator for layering liquid, includes the device main part, sets up the discernment room on the device main part, can dismantle first separator tube and the second separator tube of connecting in discernment room and intercommunication each other, connects first separator tube and is used for promoting the motion mechanism of inside layering liquid to the second separator tube of first separator tube derivation, locates the discernment inside module that just is used for discernment layering liquid layering condition of discernment room to and connect the central processing unit of discernment module and motion mechanism respectively.

In this way, the automatic device replaces manual operation of carrying out subsequent separation of layered liquid (such as blood, cell suspension, exosome-containing solution and the like), the layered liquid is filled into the first separation tube, the layered liquid in the first separation tube is controlled to flow to the second separation tube through the movement mechanism, the layered liquid flows through the recognition chamber in the conduction process and is recognized by the recognition module in the recognition chamber, the recognition module recognizes the layering condition of the layered liquid in real time and sends recognition data to the central processor for processing, the central processor processes the transmitted layering condition data of the layered liquid, and the movement mechanism is controlled to act, so that the on-off of a layering liquid channel from the first separation tube to the second separation tube is accurately controlled, the automatic operation of separating the layered liquid is completed, errors caused by manual recognition and standardized separation operations are reduced, the quality stability of separated liquid layers is improved, and the quality fluctuation of products in the same batch is reduced.

It should be noted that, the identification method adopted by the identification module includes, but is not limited to, specific identification modes such as image identification, infrared identification, capacitive identification, optical identification, etc., so as to identify the layering condition of the layering liquid, and the specific identification modes do not affect the achievement of the object of the present utility model.

In addition, the data identified by the identification module is processed by the central processing module, the central processing module controls the motion of the motion mechanism, and the algorithm of the central processing module for data processing and sending control instructions can be realized by the conventional algorithm in the prior art.

Further, the identification chamber comprises a cavity, a cover door movably connected with the cavity and a flow channel arranged in the cavity, wherein two ends of the flow channel are respectively communicated with the first separation pipe and the second separation pipe.

Further, a detachable identification hose is further arranged in the flow passage, and two ends of the identification hose are detachably connected with the first separation pipe and the second separation pipe respectively.

Further, the identification module comprises a light source module which is arranged on one side of the flow channel and used for irradiating the layered liquid flowing through the identification hose, and an identification module which is symmetrically arranged on the other side of the flow channel, and the identification module is connected with the central processor.

The identification module includes, but is not limited to, a light identifier capable of identifying a light absorption value, and a specific identification mode such as an image collector capable of acquiring image information. The optical identifier acquires the optical absorption value of the liquid layer, different liquid layers have different optical absorption values and frequencies, and the liquid layer is identified by adopting the optical absorption value of the liquid layer, so that the precision is high and the design is ingenious; the image collector realizes liquid layer identification by acquiring image information of the liquid layers and adopting different image characteristics of different liquid layers at the intersection and the boundary line of the liquid layers, and the identification precision is high.

In addition, the flow channel and the built-in identification hose are arranged to control the flux of the layered liquid led out of the first separation tube, prolong the flow path, ensure the identifiable area of the identification module and improve the identification accuracy; meanwhile, the identification chamber is provided with an openable and closable type, so that on one hand, the first separation pipe, the second separation pipe and the identification hose are convenient to connect and detach, and on the other hand, the identification chamber can be covered during operation, so that the identification chamber is in a closed and dark chamber state, the identification module is prevented from being influenced by external light, and the identification accuracy is improved.

Further, the first separating tube comprises a tube body used for loading layering liquid and provided with openings at two ends, a piston arranged in the tube body and slidably connected with the inner side wall of the tube body, and a push rod detachably connected with the piston, wherein one end opening of the tube body is communicated with the identification hose, and the other end opening of the tube body is sealed by the piston.

Further, the motion mechanism comprises a guide piece coaxially arranged with the first separation pipe, a movable seat connected with the guide piece, and a driving device for enabling the movable seat to reciprocate on the guide piece, wherein the driving device is connected with the central processor, and the push rod is detachably connected with the movable seat.

It should be noted that, the design of the detachable separating tube is adopted, so that the detachable separating tube has great practical value in practical application: when layered liquid loading is carried out, the push rod is installed, so that the liquid can be quickly absorbed; after the push rod is disassembled, independent centrifugal operation can be carried out on layered liquid in the pipe so as to realize layering; when carrying out the layering liquid separation operation, the body of having dismantled the push rod is installed, is dismantled more nimble convenient, and the push rod of having dismantled is also nimble convenient with removing the connection of seat more, the separation operation of the different volume layering liquids in the convenient body that is suitable for.

As a preferred scheme, the guide piece comprises a rotary screw rod and a guide rod which is arranged in parallel with the axis of the rotary screw rod, the rotary screw rod is in transmission connection with the driving device, and the movable seat is in threaded connection with the rotary screw rod.

As another preferable scheme, the guide piece is a sliding guide rail, the movable seat is in sliding connection with the sliding guide rail, and the movable seat is in transmission connection with the driving device.

Further, the central processor comprises a signal processing module, a controller connected with the signal processing module, a display panel connected with the controller and an operation panel connected with the controller, wherein the signal processing module is connected with the identification module, the controller is connected with the movement mechanism, the display panel and the operation panel are arranged on the outer side wall of the device main body, and the controller and the signal processing module are arranged in the device main body.

Thus, the operation panel can be used for controlling the operations of starting, closing, regulating factor concentration, separating threshold and the like of the automatic separating module in the separating process, and the separating state, separating step, separating parameters and the like of the liquid layer in the layered liquid separating process can be intuitively read in real time through the display panel; the signal processing module receives the data information from the identification module in real time, and the controller issues a control instruction after processing and analysis, so that the control of the movement mechanism is realized, and the separation operation is automatically realized.

Further, a separation cabin and a separation cabin door movably connected with the separation cabin are arranged on the side wall of the device main body, one side of the separation cabin is communicated with the identification chamber, and the movement mechanism is arranged in the separation cabin.

It should be noted that, locate the motion mechanism in the separation cabin to set up the separation hatch door that can open and shut, on the one hand in the guarantee liquid layer separation process, prevent external unexpected condition from influencing the motion of motion mechanism, on the other hand add the separation cabin after, if in the separation process, the circumstances such as breakage or the liquid leakage of separating tube appear, can keep apart explosion danger and the leakage pollution that probably arouses with the damage in the separation cabin, reduce the danger to operating personnel, guarantee the cleanness of external operating environment simultaneously. When the optical recognition method is adopted for liquid layer recognition, a separation cabin communicated with the recognition chamber is additionally arranged, the separation cabin seals the separation pipe to form a darkroom, the recognition chamber is not influenced by external light factors, and the recognition accuracy is improved.

Compared with the prior art, the utility model has the beneficial effects that:

according to the utility model, the automatic device replaces manual operation for subsequent separation of layered liquid, the identification module identifies the layered liquid layering condition in real time and sends identification data to the central processor for processing, the central processor processes the transmitted layered liquid layering condition data and controls the motion mechanism to act, the on-off of layered liquid channels from the first separation tube to the second separation tube is accurately controlled, the automatic layered liquid separation operation is completed, errors caused by manual identification and the operation of standardized separation of regenerated factor concentrated solution are reduced, the quality stability of separated liquid layers is improved, and the quality fluctuation of products in the same batch is reduced.

Drawings

FIG. 1 is a schematic diagram of the overall structure of the present utility model;

FIG. 2 is an enlarged view of a portion of FIG. 1 at A;

FIG. 3 is a schematic diagram of an identification module according to the present utility model;

FIG. 4 is a schematic diagram of a motion mechanism according to the present utility model;

fig. 5 is a schematic view of the internal structure of the present utility model.

The graphic indicia are illustrated as follows:

1-device body, 11-separation cabin, 12-separation cabin door, 2-identification room, 21-runner, 22-identification hose, 3-first separation tube, 31-body, 32-piston, 33-push rod, 4-second separation tube, 5-identification module, 51-light source module, 52-identification module, 6-movable seat, 61-rotary screw, 62-drive device, 71-signal processing module, 72-controller, 73-display panel, 74-operation panel.

Detailed Description

The utility model is further described below in connection with the following detailed description. Wherein the drawings are for illustrative purposes only and are shown in schematic, non-physical, and not intended to be limiting of the present patent; for the purpose of better illustrating embodiments of the utility model, certain elements of the drawings may be omitted, enlarged or reduced and do not represent the size of the actual product; it will be appreciated by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.

The same or similar reference numbers in the drawings of embodiments of the utility model correspond to the same or similar components; in the description of the present utility model, it should be understood that, if there is an azimuth or positional relationship indicated by terms such as "upper", "lower", "left", "right", etc., based on the azimuth or positional relationship shown in the drawings, it is only for convenience of describing the present utility model and simplifying the description, but it is not indicated or implied that the apparatus or element referred to must have a specific azimuth, be constructed and operated in a specific azimuth, and thus terms describing the positional relationship in the drawings are merely illustrative and should not be construed as limitations of the present patent, and specific meanings of the terms described above may be understood by those skilled in the art according to specific circumstances.

Example 1

As shown in fig. 1 to 5, a separation device for layered liquid includes a device body 1, a recognition chamber 2 provided on the device body 1, a first separation tube 3 and a second separation tube 4 detachably connected to the recognition chamber 2 and communicated with each other, a movement mechanism connected to the first separation tube 3 and used for pushing the first separation tube 3 to guide out the internal layered liquid to the second separation tube 4, a recognition module 5 provided inside the recognition chamber 2 and used for recognizing the layered liquid layering condition, and a central processor respectively connected to the recognition module 5 and the movement mechanism.

In this example, the stratification fluid is blood that has been subjected to centrifugal stratification.

Thus, the automatic device replaces manual operation of carrying out subsequent separation of the layered blood, the layered blood is filled into the first separation tube 3, the blood in the first separation tube 3 is controlled to flow to the second separation tube 4 through the movement mechanism, the blood flows through the recognition chamber 2 in the conduction process and is recognized by the recognition module 5 in the recognition chamber 2, the recognition module 5 recognizes the layering condition of the blood in real time and sends recognition data to the central processor for processing, the central processor processes the transmitted layering condition data of the blood, and controls the movement mechanism to act, the on-off of the blood channels of the first separation tube 3 to the second separation tube 4 is accurately controlled, the automatic operation of separating the layered blood is completed, errors caused by manual recognition and operation of standardized separation regeneration factor concentrated solution are reduced, the quality stability of separated liquid layers is improved, and the quality fluctuation of products in the same batch is reduced.

As shown in fig. 2, the identification chamber 2 comprises a cavity, a cover door movably connected with the cavity, and a flow passage 21 arranged in the cavity, wherein two ends of the flow passage 21 are respectively communicated with the first separation tube 3 and the second separation tube 4.

In this embodiment, the flow channel 21 is an arc-shaped flow channel.

As shown in fig. 2, a detachable identification hose 22 is further provided in the flow passage 21, and both ends of the identification hose 22 are detachably connected to the first separation tube 3 and the second separation tube 4, respectively.

As shown in fig. 2 and 3, the identification module 5 includes a light source module 51 disposed at one side of the flow channel 21 for irradiating the blood flowing through the identification hose 22, and an identification module 52 symmetrically disposed at the other side of the flow channel 21, and the identification module 52 is connected to the central processor.

In this embodiment, the identification module 52 is an optical identifier capable of identifying the light absorption value.

The identification module 5 emits constant light to irradiate flowing blood through the light source module 51, the light absorption value of the liquid layer is obtained through the light identifier, different liquid layers have different light absorption values and frequencies, and the liquid layer is high in identification precision and ingenious in design by adopting the liquid layer light absorption value; the flow channel 21 and the built-in identification hose 22 are arranged to control the flux of the blood led out from the first separation tube 3, prolong the flow path, ensure the identifiable area of the optical identifier and improve the identification accuracy; meanwhile, the identification chamber 2 is provided with an openable and closable type, so that on one hand, the first separation tube 3, the second separation tube 4 and the identification hose 22 are convenient to connect and detach, and on the other hand, the identification chamber 2 can be covered during operation, so that the identification chamber 2 is in a closed and dark chamber state, the adoption of an optical identifier is prevented from being influenced by external light, and the identification accuracy is improved.

As shown in fig. 4, the first separation tube 3 includes a tube body 31 for loading blood and having both ends open, a piston 32 disposed inside the tube body 31 and slidably connected to the inner side wall of the tube body 31, and a push rod 33 detachably connected to the piston 32, one end opening of the tube body 31 communicates with the identification hose 22, and the other end opening of the tube body 31 is sealed by the piston 32.

As shown in fig. 5, the movement mechanism comprises a guide coaxially provided with the first separation tube 3, a movable seat 6 connected to the guide, and a driving device 62 for reciprocating the movable seat 6 on the guide, the driving device 62 being connected to the central processor, and a push rod 33 being detachably connected to the movable seat 6.

In this embodiment, the guide member includes a rotating screw 61 and a guide rod disposed parallel to the axis of the rotating screw 61, the rotating screw 61 is in transmission connection with a driving device 62, and the movable seat 6 is in threaded connection with the rotating screw 61.

In this embodiment, the driving device 62 is a motor.

Adopt detachable first separator tube design, have very big practical value: when blood is loaded, the push rod 33 is installed, so that the tube 31 can rapidly suck liquid; after the push rod 33 is disassembled, the blood in the tube 31 can be subjected to independent centrifugal operation to realize layering; when the layered blood separation operation is carried out, the pipe body 31 with the push rod 33 detached is more flexible and convenient to install and detach, and the connection between the detached push rod 33 and the movable seat 6 is also more flexible and convenient, so that the separation operation of blood with different volumes in the pipe body 31 is convenient and applicable.

As shown in fig. 5, the central processor includes a signal processing module 71, a controller 72 connected to the signal processing module 71, a display panel 73 connected to the controller 72, and an operation panel 74 connected to the controller 72, the signal processing module 71 is connected to the identification module 5, the controller 72 is connected to the movement mechanism, the display panel 73 and the operation panel 74 are provided on the outer side wall of the apparatus main body 1, and the controller 72 and the signal processing module 71 are provided inside the apparatus main body 1.

Thus, the operations of starting, closing, regulating factor concentration, separating threshold and the like of the automatic separating module in the separating process can be controlled through the operation panel 74, and the separating state, separating step and separating parameter of the liquid layer in the blood separating process can be intuitively read in real time through the display panel 73; the signal processing module 71 receives the data information from the identification module 52 in real time, and the controller 72 issues control instructions after processing and analysis to control the movement mechanism and automatically realize separation operation.

Further, a separation cabin 11 and a separation cabin door 12 movably connected with the separation cabin 11 are arranged on the side wall of the device main body 1, one side of the separation cabin 11 is communicated with the identification chamber 2, and the movement mechanism is arranged in the separation cabin 11.

The motion mechanism is arranged in the separation cabin 11, and the openable separation cabin door 12 is arranged, so that on one hand, the motion of the motion mechanism is prevented from being influenced by external accidents in the liquid layer separation process, and on the other hand, after the separation cabin 11 is additionally arranged, if the separation pipe is broken or liquid leaks and the like in the separation process, the explosion danger and leakage pollution possibly caused by damage can be isolated in the separation cabin 11, the danger to operators is reduced, and meanwhile, the cleaning of the external operation environment is ensured.

In this embodiment, add the separation cabin 11 with discernment room 2 intercommunication, the separation cabin 11 is also airtight with the separating tube, forms the darkroom, guarantees that discernment room 2 does not receive the influence of external light factor, improves discernment accuracy.

Example 2

The present embodiment is similar to embodiment 1, except that in the present embodiment, the recognition module 52 is an image collector.

In this way, the identification module 5 emits the blood flowing through the constant light through the light source module 51, acquires the image information of the liquid layer through the image collector, and realizes the liquid layer identification by adopting different image characteristics of different liquid layers at the intersection and the dividing line of the liquid layer, so that the precision is high and the design is ingenious; meanwhile, the identification chamber 2 is provided with an openable and closable type, so that on one hand, the first separation tube 3, the second separation tube 4 and the identification hose 5 are convenient to connect and detach, and on the other hand, the identification chamber 2 can be covered during operation, so that the identification chamber 2 is in a closed and dark chamber state, the light source module 51 is ensured to irradiate a liquid layer in the identification tube 5 stably, the light source module is not influenced by an external environment light source, an image under a stable and consistent light source is ensured to be obtained by an image collector, error influence factors are reduced, and the identification accuracy is improved.

Other structures and principles of this embodiment are the same as those of embodiment 1.

Example 3

The present embodiment is similar to embodiment 1, except that in this embodiment, the guide member is a sliding rail, the movable seat 6 is slidably connected to the sliding rail, and the movable seat 6 is drivingly connected to the driving device 62.

In this embodiment, the driving device 62 is a motor. Other structures and principles of this embodiment are the same as those of embodiment 1.

Example 4

The present embodiment is similar to embodiment 2, except that in this embodiment, the guide member is a sliding rail, the movable seat 6 is slidably connected to the sliding rail, and the movable seat 6 is drivingly connected to the driving device 62.

In this embodiment, the driving device 62 is a motor. Other structures and principles of this embodiment are the same as those of embodiment 2.

Example 5

The present embodiment is similar to embodiment 1, except that in this embodiment, the guide member is a sliding rail, the movable seat 6 is slidably connected to the sliding rail, and the movable seat 6 is drivingly connected to the driving device 62.

In this embodiment, the driving device 62 is a hydraulic cylinder. Other structures and principles of this embodiment are the same as those of embodiment 1.

Example 6

The present embodiment is similar to embodiment 2, except that in this embodiment, the guide member is a sliding rail, the movable seat 6 is slidably connected to the sliding rail, and the movable seat 6 is drivingly connected to the driving device 62.

In this embodiment, the driving device 62 is a hydraulic cylinder. Other structures and principles of this embodiment are the same as those of embodiment 2.

It is to be understood that the above examples of the present utility model are provided by way of illustration only and not by way of limitation of the embodiments of the present utility model. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. Any modification, equivalent replacement, improvement, etc. which come within the spirit and principles of the utility model are desired to be protected by the following claims.

Claims (10)

1. The utility model provides a separator for layering liquid, its characterized in that includes device main part (1), sets up in discernment room (2) on device main part (1), can dismantle connect in discernment room (2) and first separator tube (3) and second separator tube (4) of intercommunication each other, connect first separator tube (3) just are used for promoting the motion of inside layering liquid to second separator tube (4) is derived to first separator tube (3), locates discernment module (5) of discernment room (2) inside and being used for discernment layering liquid layering condition, and connect respectively discernment module (5) with the central processor of motion.

2. The separation device for layered liquids according to claim 1, characterized in that the identification chamber (2) comprises a cavity, a cover door movably connected to the cavity, and a flow channel (21) provided in the cavity, both ends of the flow channel (21) being in communication with the first separation tube (3) and the second separation tube (4), respectively.

3. A separator for a layered liquid according to claim 2, characterized in that a detachable identification hose (22) is further provided in the flow channel (21), both ends of the identification hose (22) being detachably connected to the first separator tube (3) and the second separator tube (4), respectively.

4. A separation device for a layered liquid according to claim 3, characterized in that the identification module (5) comprises a light source module (51) arranged at one side of the flow channel (21) for illuminating the layered liquid flowing in the identification hose (22), and an identification module (52) symmetrically arranged at the other side of the flow channel (21), the identification module (52) being connected to the central processor.

5. A separation device for a layered liquid according to claim 3, characterized in that the first separation tube (3) comprises a tube body (31) for loading a layered liquid and having openings at both ends, a piston (32) disposed inside the tube body (31) and slidably connected to an inner side wall of the tube body (31), and a push rod (33) detachably connected to the piston (32), one end opening of the tube body (31) being in communication with the identification hose (22), and the other end opening of the tube body (31) being sealed by the piston (32).

6. A separating device for a layered liquid according to claim 5, characterized in that the movement means comprise a guide coaxially arranged with the first separating tube (3), a mobile seat (6) connected to the guide, and drive means (62) for reciprocating the mobile seat (6) on the guide, the drive means (62) being connected to the central processor, the push rod (33) being detachably connected to the mobile seat (6).

7. A separating device for a layered liquid according to claim 6, characterized in that the guide comprises a rotating screw (61) and a guide rod arranged parallel to the axis of the rotating screw (61), the rotating screw (61) being in driving connection with the driving means (62), the moving seat (6) being in threaded connection with the rotating screw (61).

8. A separating device for a layered liquid according to claim 6, characterized in that the guide is a sliding rail, the mobile seat (6) being in sliding connection with the sliding rail, the mobile seat (6) being in driving connection with the driving device (62).

9. The separation device for layered liquids according to claim 1, characterized in that the central processor comprises a signal processing module (71), a controller (72) connected to the signal processing module (71), a display panel (73) connected to the controller (72), and an operation panel (74) connected to the controller (72), the signal processing module (71) is connected to the identification module (5), the controller (72) is connected to the movement mechanism, the display panel (73) and the operation panel (74) are provided on the outer side wall of the device body (1), and the controller (72) and the signal processing module (71) are provided inside the device body (1).

10. The separating device for layered liquids according to claim 1, characterized in that a separating compartment (11) is provided on the side wall of the device body (1), and a separating compartment door (12) is movably connected to the separating compartment (11), one side of the separating compartment (11) is communicated with the identification chamber (2), and the movement mechanism is provided in the separating compartment (11).

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