CN219091869U

CN219091869U - Beta cyclodextrin mixes homogeneity mechanism

Info

Publication number: CN219091869U
Application number: CN202320106288.5U
Authority: CN
Inventors: 王林勇; 牛丽峰
Original assignee: Shandong Jiake Biotechnology Co ltd
Current assignee: Shandong Jiake Biotechnology Co ltd
Priority date: 2023-02-03
Filing date: 2023-02-03
Publication date: 2023-05-30
Anticipated expiration: 2033-02-03

Abstract

The utility model relates to the field of crushing and grinding devices, in particular to a beta-cyclodextrin mixing and homogenizing mechanism. The utility model provides a beta cyclodextrin mixes homogeneity mechanism, its characterized in that, including the casing that has the lid, the upside of casing is equipped with the frame, fixedly connected with at least one running roller and at least one stirring rake in the frame, and the frame below is equipped with the mill, the mill rotates to be connected in the casing, and the mill includes toper portion and encircles toper portion setting at recess portion, the lower extreme setting of running roller and stirring rake is in the annular groove of recess portion. Aiming at the defects of the prior art, the technical problem to be solved by the utility model is to provide the beta cyclodextrin mixing and homogenizing mechanism which has good grinding effect and is easy to clean.

Description

Beta cyclodextrin mixes homogeneity mechanism

Technical Field

The utility model relates to the field of crushing and grinding devices, in particular to a beta-cyclodextrin mixing and homogenizing mechanism.

Background

Betacyclodextrin is a white to pale yellow powder with slightly specific fragrance of pectin, slightly sweet and slightly sour. The beta-cyclodextrin is used as a novel pharmaceutical auxiliary material, is mainly used for increasing the stability of the medicine, preventing the medicine from being oxidized and decomposed, improving the dissolution and bioavailability of the medicine, reducing the toxic and side effects of the medicine and masking the peculiar smell and odor of the medicine.

The requirements of the medicinal-grade beta-dextrin on the quality are much higher than those of normal dextrin, for example, the fineness and uniformity requirements of the medicinal-grade beta-dextrin are strict, the medicinal-grade beta-dextrin has better dispersibility, and the medicinal-grade beta-dextrin can be well mixed with medicines uniformly.

The conventional beta dextrin homogenizing device comprises a ball mill and a colloid mill, wherein the ball mill has low working efficiency, high consumed energy, high friction loss between a grinding body and a machine body and strong vibration and noise during operation; the residual materials on the movable disc and the static disc of the adhesive film are not cleaned well, so that not only is the material wasted, but also the safety of medicines is affected. In order to meet the actual production needs, the technical staff developed a novel homogenizing device suitable for pharmaceutical grade betadextrin.

Disclosure of Invention

Aiming at the defects of the prior art, the technical problem to be solved by the utility model is to provide the beta cyclodextrin mixing and homogenizing mechanism which has good grinding effect and is easy to clean.

The technical scheme for solving the technical problems is as follows:

the utility model provides a beta cyclodextrin mixes homogeneity mechanism, its characterized in that, including the casing that has the lid, the upside of casing is equipped with the frame, fixedly connected with at least one running roller and at least one stirring rake in the frame, and the frame below is equipped with the mill, the mill rotates to be connected in the casing, and the mill includes toper portion and encircles toper portion setting at recess portion, the lower extreme setting of running roller and stirring rake is in the annular groove of recess portion.

Further, a driving device is connected below the grinding disc.

Further, a supporting platform is arranged in the shell, the grinding disc is rotatably supported on the supporting platform, the driving device is arranged below the supporting platform, and a shaft of the driving device penetrates through the supporting platform to be connected with the grinding disc.

Further, a rotary sealing device is arranged between the outer wall of the upper end of the grinding disc and the machine shell.

Further, the roller is fixedly connected to the frame through a telescopic rod.

Further, the telescopic rod is an electric telescopic rod or a hydraulic cylinder.

Further, the upper end of stirring rake is equipped with the motor, and motor fixed connection is in the frame.

Further, the longitudinal section of annular groove bottom is circular-arc, the shape of stirring rake and the shape phase-match of annular groove, and the lower extreme of stirring rake can paste and lean on annular groove bottom.

Further, three rollers and three stirring paddles are alternately arranged on the frame.

Further, a discharging hopper with a discharging opening facing the conical part is arranged in the middle of the frame.

The beneficial effects of the utility model are as follows:

according to the utility model, the grinding disc, the roller and the stirring paddle are arranged, the roller can grind and crush the betadextrin on the grinding disc, the stirring paddle can stir and mix the betadextrin, so that the mixed homogenizing treatment of the betacyclodextrin is realized, the product with uniform fineness is obtained, the betadextrin is positioned on the grinding disc and is easy to collect, and the grinding disc, the roller and the stirring paddle are easy to clean and disassemble and install, so that the method is suitable for homogenizing treatment of the medicine-grade betadextrin.

Drawings

FIG. 1 is a schematic diagram of the structure of the present utility model;

in the figure: 1. the machine comprises a shell, a machine frame, a discharging hopper, a roller, a telescopic rod, a stirring paddle, a motor, a grinding disc, a conical part, a groove part, a driving device, a supporting platform and a rotary sealing device.

Detailed Description

The principles and features of the present utility model are described below with reference to the drawings, the illustrated embodiments are provided for illustration only and are not intended to limit the scope of the present utility model.

As shown in fig. 1, the beta-cyclodextrin mixing and homogenizing mechanism of the embodiment comprises a casing 1 with a cover, a frame 2 is arranged on the upper side of the casing 1, at least one roller 4 and at least one stirring paddle 6 are fixedly connected to the frame 2, a grinding disc 8 is arranged below the frame 2, the grinding disc 8 is rotatably connected in the casing 1, the grinding disc 8 comprises a conical portion 80 and a groove portion 81 surrounding the conical portion 80, and the lower ends of the roller 4 and the stirring paddle 6 are arranged in the annular groove of the groove portion 81. Further, a discharging hopper 3 with a discharging opening facing the conical part 80 is arranged in the middle of the frame 2. The betadextrin falls from the hopper 3 onto the conical portion 80, allowing it to be more evenly dispersed in the annular groove.

As an alternative embodiment, three rollers 4 and three stirring paddles 6 are alternately arranged on the frame 2. The number of the rollers 4 and the paddles 6 may be set according to the actual use effect.

A driving device 9 is connected below the grinding disc 8. Further, a supporting platform 10 is arranged in the casing 1, the grinding disc 8 is rotatably supported on the supporting platform 10, the driving device 9 is arranged below the supporting platform 10, and a shaft of the driving device 9 penetrates through the supporting platform 10 to be connected with the grinding disc 8. Alternatively, the driving means 9 comprises a driving motor 7 and a decelerator.

Specifically, the longitudinal section of annular groove bottom is circular-arc, the shape of stirring rake 6 and the shape phase-match of annular groove, the lower extreme of stirring rake 6 can paste and lean on annular groove bottom. Further, a motor 7 is arranged at the upper end of the stirring paddle 6, and the motor 7 is fixedly connected to the frame 2.

It will be appreciated that the shape of the peripheral end of the roller 4 is also matched to the shape of the annular recess.

In this embodiment, the roller 4 is fixedly connected to the frame 2 through a telescopic rod 5. Further, the telescopic rod 5 is an electric telescopic rod or a hydraulic cylinder. The distance between the roller 4 and the bottom of the annular groove can be adjusted by the contraction or the extension of the telescopic rod 5 so as to adjust the grinding effect.

In order to place the beta-dextrin to spill from the millstone 8, a rotary sealing device 11 is arranged between the outer wall of the upper end of the millstone 8 and the machine shell 1. A floating seal may be selected as the rotary seal device 11.

When the device is used, the cover of the shell 1 is opened, the to-be-treated beta-dextrin is uniformly added into the device from the discharging hopper 3, the driving device 9 drives the grinding disc 8 to rotate, the roller 4 grinds the beta-dextrin on the grinding disc 8, the stirring paddle 6 not only rotates the mixed material to realize the mixed homogenization treatment of the beta-cyclodextrin, the product with uniform fineness is obtained, the beta-dextrin is positioned on the grinding disc 8 and is easy to collect, and the grinding disc 8, the roller 4 and the stirring paddle 6 are easy to clean and disassemble and install, so that the device is suitable for the homogenization treatment of the medicine-grade beta-dextrin.

It is apparent that the above examples are given by way of illustration only and are not limiting of the embodiments. Other variations or modifications of the above description will be apparent to those of skill in the art. It is not necessary here nor is it exhaustive of all embodiments. While still being apparent from variations or modifications that may be made by those skilled in the art are within the scope of the utility model.

Claims

1. The utility model provides a beta cyclodextrin mixes homogeneity mechanism, its characterized in that, including casing (1) that has the lid, the upside of casing (1) is equipped with frame (2), fixedly connected with at least one running roller (4) and at least one stirring rake (6) on frame (2), and frame (2) below is equipped with mill (8), mill (8) rotate and connect in casing (1), and mill (8) include toper portion (80) and encircle toper portion (80) setting in recess portion (81), the lower extreme setting of running roller (4) and stirring rake (6) is in the annular groove of recess portion (81).

2. The beta-cyclodextrin mixing and homogenizing mechanism according to claim 1, wherein a driving device (9) is connected below the grinding disc (8).

3. The beta-cyclodextrin mixing and homogenizing mechanism according to claim 2, wherein a supporting platform (10) is arranged in the machine shell (1), the grinding disc (8) is rotatably supported on the supporting platform (10), the driving device (9) is arranged below the supporting platform (10), and a shaft of the driving device (9) penetrates through the supporting platform (10) to be connected with the grinding disc (8).

4. A mechanism for homogenizing a mixture of betacyclodextrin according to any one of claims 1 to 3, characterized in that a rotary sealing means (11) is provided between the outer wall of the upper end of the grinding disc (8) and the housing (1).

5. The beta-cyclodextrin mixing and homogenizing mechanism according to claim 1, wherein the roller (4) is fixedly connected to the frame (2) through a telescopic rod (5).

6. The beta-cyclodextrin mixing homogenizing mechanism of claim 5, wherein the telescopic rod (5) is an electric telescopic rod or a hydraulic cylinder.

7. The beta-cyclodextrin mixing and homogenizing mechanism according to claim 1, wherein a motor (7) is arranged at the upper end of the stirring paddle (6), and the motor (7) is fixedly connected to the frame (2).

8. The mixing and homogenizing mechanism for the betacyclodextrin according to claim 1, wherein the longitudinal section of the bottom of the annular groove is arc-shaped, the shape of the stirring paddle (6) is matched with that of the annular groove, and the lower end of the stirring paddle (6) can be abutted against the bottom of the annular groove.

9. The mixing and homogenizing mechanism of the betacyclodextrin according to claim 1, wherein three rollers (4) and three stirring paddles (6) are alternately arranged on the frame (2).

10. The beta-cyclodextrin mixing and homogenizing mechanism according to claim 1, wherein a blanking hopper (3) with a blanking port facing the conical part (80) is arranged in the middle of the frame (2).