CN219089520U - Thrombus aspiration thrombolysis protection device - Google Patents

Abstract

The embodiment of the application discloses a thrombus aspiration thrombolysis protection device, which comprises: the infusion device comprises a tube body, a suction device, an infusion device and a protection device, wherein the tube body is provided with a distal end which is used for extending into a blood vessel and a proximal end which is opposite to the distal end, and the interior of the tube body is provided with a suction channel and a thrombolysis channel; the suction device is communicated with the suction channel through the suction port and is used for sucking thrombus from a blood vessel through the suction channel; the infusion device is communicated with the thrombolysis channel through the medicine inlet and is used for injecting thrombolytic medicine into the blood vessel through the thrombolysis channel to perform thrombolysis; the protecting device comprises a linear connecting part and a basket connected with one end of the connecting part, the connecting part can drive the basket to penetrate through the suction channel and extend out from a first opening of the suction channel at the distal end, the other end of the connecting part can extend out from a second opening of the suction channel at the proximal end, and the basket is used for collecting thrombus. The device can aspirate thrombus, dissolve thrombus and prevent thrombus from escaping.

Description

Thrombus aspiration thrombolysis protection device

Technical Field

The embodiment of the application relates to the technical field of medical instruments, in particular to a thrombus aspiration thrombolysis protection device.

Background

At present, the treatment method of the thrombotic diseases mainly comprises drug conservation treatment and operation treatment, and the drug conservation treatment mainly comprises anticoagulation treatment, so as to reduce mortality, recurrence rate and postthrombotic syndrome, but the anticoagulation treatment has slow effect, is difficult to thoroughly dissolve thrombus, and has high bleeding risk. The operation treatment mainly comprises traditional surgery and intravascular interventional operation treatment, and the angiotomy and thrombus removal operation is used as the traditional surgery, so that the defects of large wound, slow postoperative recovery and more complications are overcome, and the clinical practice is basically not adopted at present. With the development of medical imaging technology, intravascular interventional therapy has small trauma, quick recovery and good effect, and gradually becomes a main operation mode of thrombotic diseases.

The conventional interventional mechanical thrombus extraction mainly comprises the steps of extending a suction catheter into a blood vessel, carrying out negative pressure suction on thrombus through the suction catheter, and sucking the thrombus out of the blood vessel so as to reconstruct blood flow in the blood vessel. The interventional mechanical thrombus taking has the problems that when thrombus is positioned in a narrow blood vessel or the thrombus is attached to the wall of the blood vessel, the effect of pure negative pressure thrombus taking is very limited, and the operation risk is high. In addition, thrombus can easily escape and block other blood vessel branches, so that secondary blockage and the like are caused.

Disclosure of Invention

In view of the above-mentioned problems in the prior art, embodiments of the present application provide a thrombus aspiration thrombolysis protection device, which can aspirate thrombus, and can also infuse thrombolytic drugs into blood vessels to perform thrombolysis, and can also prevent thrombus from escaping, thereby achieving a better therapeutic effect.

In order to solve the above problems, the technical solution provided in the embodiments of the present application is:

a thrombus aspiration thrombolysis device comprising:

a tube body having a distal end for extending into a blood vessel and a proximal end opposite to the distal end, the interior of the tube body having a suction passage penetrating the distal end and the proximal end and a thrombolysis passage surrounding the suction passage and extending in a longitudinal direction of the tube body, a drug outlet communicating with the thrombolysis passage being provided at a position on the tube body near the distal end, a drug inlet communicating with the thrombolysis passage and a suction port communicating with the suction passage being provided at a position on the tube body near the proximal end, respectively;

a suction device communicating with the suction passage through the suction port for sucking thrombus from a blood vessel through the suction passage;

the infusion device is communicated with the thrombolytic channel through the medicine inlet and is used for injecting thrombolytic medicine into the blood vessel through the thrombolytic channel to perform thrombolysis;

the protecting device comprises a linear connecting part and a basket connected with one end of the connecting part, wherein the connecting part can drive the basket to penetrate through the suction channel and extend out of the first opening of the suction channel at the far end, the other end of the connecting part can extend out of the second opening of the suction channel at the near end, and the basket is used for collecting thrombus.

In some embodiments, the shaft includes a thrombolytic catheter and a first aspiration catheter threaded through the thrombolytic catheter, a lumen of the first aspiration catheter forming the aspiration channel, a lumen between the thrombolytic catheter and the first aspiration catheter forming the thrombolytic channel.

In some embodiments, the pipe body further comprises a first tee and a second tee;

the first three-way joint is provided with a first interface, a second interface and a third interface, the thrombolysis catheter is connected with the first interface, the first suction catheter extends into the first three-way joint through the first interface, and the third interface forms the medicine inlet;

the second three-way joint is provided with a fourth interface, a fifth interface and a sixth interface, the fourth interface is connected with the first suction catheter through the second interface, the fifth interface forms the second opening, and the sixth interface forms the suction port.

In some embodiments, the first interface and the second interface are in communication through a first joint lumen that is rectilinear, and the third interface is located between the first interface and the second interface;

the fourth interface is communicated with the fifth interface through a linear second joint inner cavity, and the sixth interface is located between the fourth interface and the fifth interface.

In some embodiments, a fourth port of the second three-way connector extends into the first connector lumen via the second port and connects with the first aspiration catheter.

In some embodiments, the connecting member comprises a core wire having one end connected to the basket and the other end capable of protruding through the second opening; or (b)

The connecting part comprises a second suction duct, one end of the second suction duct is connected with the basket, and the other end of the second suction duct can extend out through the second opening; or (b)

The connecting component comprises a containing conduit and a core wire penetrating through the containing conduit, one end of the core wire extends out of one end of the containing conduit, the other end of the core wire extends out of the other end of the containing conduit, the other end of the containing conduit can extend out of the second opening, one end of the basket is connected with one end of the containing conduit, the other end of the basket is connected with one end of the core wire, and the containing conduit and the core wire are used for mutually matching and adjusting the distance between two ends of the basket so as to drive the basket to be unfolded or folded.

In some embodiments, the protective device further comprises a handle connected to the other end of the core wire, the other end of the second aspiration catheter, or the other end of the receiving catheter.

In some embodiments, the basket is spindle-shaped, the basket having an open end and a closed end opposite the open end, the open end facing toward and connected to one end of the connecting member, or the closed end facing toward and connected to one end of the connecting member; or (b)

The basket is in a horn shape, the basket is provided with a necking end and a flaring end which are opposite, the diameter of the flaring end is larger than that of the necking end, and the necking end is connected with one end of the connecting component.

In some embodiments, the basket includes a multi-layered mesh structure in a stacked arrangement.

In some embodiments, a first X-ray mark is arranged at a position of the distal end of the tube body close to the medicine outlet; and/or

And a second X-ray mark is arranged at one end of the basket away from the connecting part.

The thrombus aspiration thrombolysis protection device of the embodiment of the application can aspirate thrombus from blood vessels, can infuse thrombolytic drugs into the blood vessels to dissolve thrombus, can prevent thrombus from escaping, and can form better treatment effect.

Drawings

Other features, objects and advantages of the present application will become more apparent upon reading of the detailed description of non-limiting embodiments, made with reference to the following drawings, in which:

FIG. 1 is a schematic view of a thrombus aspiration thrombolysis device according to an embodiment of the present application;

FIG. 2 is a cross-sectional view of a portion of the structure of a pipe body;

FIG. 3 is an enlarged view of a portion of a pipe body;

FIG. 4 is a schematic view of a first embodiment of a protection device;

FIG. 5 is a schematic view of a second embodiment of a protective device;

FIG. 6 is a schematic view of a third embodiment of a protective device;

FIG. 7 is a schematic view of a fourth embodiment of a protection device;

FIG. 8 is a schematic view of a fifth embodiment of a protective device;

fig. 9 is a schematic structural view of a sixth embodiment of the protection device.

Reference numerals illustrate:

100-pipe body; 110-thrombolytic catheter; 111-thrombolytic channel; 112-a medicine outlet; 120-a first aspiration catheter; 121-a suction channel; 122-a first opening; 130-a first three-way joint; 131-a first interface; 132-a second interface; 133-a third interface; 140-a second three-way joint; 141-fourth interface; 142-fifth interface; 143-sixth interface; 150-first X-ray marking;

200-suction device; 210-an extension tube;

300-infusion device; 310-liquid conveyor; 320-another extension tube;

400-protection device; 410-connecting parts; 411-core wire; 412-a second aspiration conduit; 413-housing a catheter; 420-basket; 430-handle; 440-stress relief sleeve; 450-second X-ray marker.

Detailed Description

The present application is described in further detail below with reference to the drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the utility model and are not limiting of the utility model. It should be noted that, for convenience of description, only the portions related to the present utility model are shown in the drawings.

It should be noted that, in the case of no conflict, the embodiments and features in the embodiments may be combined with each other. The present application will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.

Referring to fig. 1 to 4, an embodiment of the present application provides a thrombus aspiration thrombolysis device including a tube body 100, an aspiration device 200, an infusion device 300, and a protection device 400.

The tube body 100 has opposite distal and proximal ends, the distal end for extending into a blood vessel. Alternatively, the shaft 100 may be an elongated tubular structure that is capable of extending into a blood vessel, or the shaft 100 may include at least one elongated tubular structure that is capable of extending into a blood vessel. The interior of the tube body 100 is provided with a suction channel 121 and a thrombolysis channel 111, the suction channel 121 penetrates through the distal end and the proximal end, and the thrombolysis channel 111 surrounds the suction channel 121 and extends along the length direction of the tube body 100. Alternatively, one end of the thrombolytic channel 111 may extend to a position near the distal end and the other end of the thrombolytic channel 111 may extend to a position near the proximal end.

A medicine outlet 112 is formed in the tube body 100 at a position close to the distal end, and the medicine outlet 112 may be communicated with the thrombolytic channel 111. Optionally, the tube body 100 may be provided with a plurality of drug outlets 112, and the plurality of drug outlets 112 may be uniformly arranged on the tube body 100 at a position near the distal end, so as to uniformly output thrombolytic drugs into blood vessels. For example, the plurality of medicine outlets 112 may be uniformly arranged at equal intervals along the axial direction of the tube body 100, uniformly arranged at equal intervals along the circumferential direction of the tube body 100, or may be spirally arranged along the tube body 100. In particular embodiments, the drug outlet 112 may take a variety of shapes, for example, the drug outlet 112 may be a circular hole, a bar-shaped hole, or a hole of other shape. A medicine inlet and a suction inlet are respectively arranged on the tube body 100 at positions close to the proximal end, the medicine inlet is communicated with the thrombolysis channel 111, and the suction inlet is communicated with the suction channel 121.

The aspiration device 200 communicates with the aspiration channel 121 through the aspiration port for aspirating thrombus from a blood vessel through the aspiration channel 121. In particular embodiments, the suction device 200 may employ various devices capable of providing suction power. Alternatively, the aspiration device 200 may employ a manual aspiration device 200, such as a manual negative pressure pump or syringe, or the like. The suction device 200 may also employ an automatic suction device 200, such as a hydraulic pump or an electric negative pressure pump, or the like. Optionally, the suction device 200 may be connected to the suction port via the extension tube 210, so that the surgical space can be expanded, and the medical staff can operate the suction device 200 conveniently.

The infusion device 300 is communicated with the thrombolytic channel 111 through the drug inlet and is used for injecting thrombolytic drugs into blood vessels through the thrombolytic channel 111 for thrombolysis. In particular, the infusion set 300 may be used with various devices capable of delivering a medical fluid into the thrombolytic channel 111. Alternatively, the infusion device 300 may be a manual infusion device 300. For example, the infusion device 300 may include a syringe. Also for example, the infusion set 300 may include a fluid delivery device 310 and a syringe (not shown), the fluid delivery device 310 may be coupled to the drug inlet, a syringe containing a thrombolytic drug may be mounted to the fluid delivery device 310, and a healthcare worker may deliver the thrombolytic drug from the syringe into the thrombolytic channel 111 by grasping the handle 430 of the fluid delivery device 310 and delivering the thrombolytic drug into the blood vessel through the thrombolytic channel 111. Alternatively, the infusion device 300 may be an automatic infusion device 300. For example, the infusion device 300 may be an infusion pump capable of automatically infusing fluid. Optionally, the infusion device 300 may further include a vibration generator that may transmit vibrations into the blood vessel through the thrombolytic drug in the thrombolytic channel 111 to assist in thrombolysis. Optionally, the infusion device 300 may be connected to the drug inlet through another extension tube 320 to expand the surgical space and facilitate the operation of the infusion device 300 by a medical staff.

The protection device 400 includes a connection member 410 and a basket 420, the connection member 410 may be in a wire shape, one end of the connection member 410 may be connected to the basket 420, the connection member 410 is used to drive the basket 420 to pass through the suction channel 121 and protrude through a first opening 122 of the suction channel 121 at the distal end, the other end of the connection member 410 is capable of protruding through a second opening of the suction channel 121 at the proximal end, and the basket 420 is used to collect thrombus. That is, the basket 420 may be extended into the suction channel 121 through the second opening, and the basket 420 may be extended through the second opening under the driving of the connection part 410.

The thrombus aspiration thrombolysis protection device of the embodiment of the application, the tube body 100 can be input into a blood vessel of a patient, and the interior of the tube body 100 is provided with an aspiration channel 121 and a thrombolysis channel 111; the aspiration device 200 is connected to the aspiration channel 121 via an aspiration port, and thrombi can be aspirated from the blood vessel via the aspiration channel 121; the infusion device 300 is connected with the thrombolysis channel 111 through the medicine inlet, and the infusion device 300 can input thrombolytic medicine into the blood vessel through the thrombolysis channel 111 for thrombolysis; the protection device 400 comprises a connecting part 410 and a basket 420, wherein the basket 420 can extend into a blood vessel through the suction channel 121 under the drive of the connecting part 410 so as to collect thrombus and avoid secondary blockage caused by thrombus escape. For example, during thrombolysis or aspiration, basket 420 may be placed on the distal side of the thrombus segment to prevent thrombus from escaping during thrombolysis or aspiration. Thus, the thrombus sucking and thrombolysis protection device can suck thrombus from blood vessels, can input thrombolytic drugs into the blood vessels to perform thrombolysis, can prevent thrombus from escaping, and can form better treatment effect.

In some embodiments, as shown in fig. 2, the shaft 100 includes a thrombolytic catheter 110 and a first aspiration catheter 120 penetrating the thrombolytic catheter 110, a lumen of the first aspiration catheter 120 forming the aspiration channel 121, and a lumen between the thrombolytic catheter 110 and the first aspiration catheter 120 forming the thrombolytic channel 111. The tube body 100 is formed by the thrombolysis tube 110 and the first aspiration tube 120 which are nested inside and outside, which is beneficial to reducing the diameter of the tube body 100, so that the tube body 100 can extend into a blood vessel with smaller diameter, thereby expanding the application field of the thrombus aspiration thrombolysis protection device.

Alternatively, one end of the thrombolytic catheter 110 may extend to a position near the distal end of the tube body 100, i.e., a position near one end of the first aspiration catheter 120, and one end of the thrombolytic catheter 110 may be fixedly connected to the outer wall of the first aspiration catheter 120 through a constriction structure and close the one end face opening of the thrombolytic channel 111. The other end of the thrombolytic catheter 110 may extend to a position close to the other end of the first aspiration catheter 120, and the other end of the thrombolytic catheter 110 may be fixedly connected to the outer wall of the first aspiration catheter 120 to close the other end face opening of the thrombolytic channel 111. The drug inlet can be arranged on the side wall of the thrombolysis catheter 110, so that the infusion device 300 is convenient for medical staff to operate and is easy to realize.

Alternatively, the suction port may be provided on a side wall of the first suction catheter 120 to facilitate operation by a healthcare worker. In some cases, the suction port may also be the same opening as the second opening. For example, both the suction port and the second opening may be formed by a proximal end face opening of the first suction catheter 120.

In some embodiments, the tubular body 100 further comprises a first tee joint 130 and a second tee joint 140. The first three-way joint 130 has a first interface 131, a second interface 132 and a third interface 133, the thrombolytic catheter 110 is connected to the first interface 131, the first aspiration catheter 120 extends into the first three-way joint 130 via the first interface 131, and the third interface 133 forms the drug inlet. The second three-way joint 140 has a fourth joint 141, a fifth joint 142 and a sixth joint, the fourth joint 141 being connected to the first suction duct 120 through the second joint 132, the fifth joint 142 forming the second opening, the sixth joint forming the suction port. The suction device 200 and the infusion set 300 can be conveniently connected to the tube body 100 by providing the first three-way joint 130 and the second three-way joint 140.

Optionally, the first interface 131 and the second interface 132 are communicated through a first joint cavity with a straight shape, and the third interface 133 is located between the first interface 131 and the second interface 132; the fourth interface 141 and the fifth interface 142 are communicated through a linear second joint cavity, and the sixth interface is located between the fourth interface 141 and the fifth interface 142. In fact, the suction channel 121 is formed by the lumen of the first suction catheter 120 and the first joint inner cavity, and the formed suction channel 121 extends along the length direction of the tube body 100, has no obvious bending part, is beneficial to inserting the basket 420 and the connecting part 410 into the suction channel 121 and pushing in the suction channel 121, and is convenient for medical staff to operate.

Optionally, the fourth port 141 of the second three-way connector 140 extends into the first connector lumen via the second port 132 and is connected to the first suction catheter 120. That is, the fourth port 141 of the second three-way connector 140 extends into the first connector lumen directly to the first suction catheter 120. Therefore, the first joint inner cavity does not need to be provided with a switching structure, which is beneficial to simplifying the internal structure of the first three-way joint 130, improving the tightness and reducing the production cost.

Optionally, the first joint inner cavity may include a first cavity section and a second cavity section, the first interface 131 is disposed at one end of the first cavity section, the other end of the first cavity section is connected with the second cavity section, the other end of the second cavity section is provided with the second interface 132, and the third interface 133 may be disposed on a side wall of the first cavity section. The first cavity section may have a cylindrical shape, and the diameter of the second cavity section may be gradually reduced from the second port 132 to the first port 131. Thrombolytic catheter 110 may extend into the first lumen segment via first port 131 and to a position proximate third port 133, and first aspiration catheter 120 may extend into the first lumen segment via first opening 122 and to a position where the first lumen segment and the second lumen segment are joined to each other. The second three-way connection 140 may be threaded through the second lumen segment, and the fourth port 141 extends into the first lumen segment and connects with the first suction catheter 120. Optionally, the outer wall of the second three-way joint 140 may be attached to the inner wall of the second cavity section to achieve a seal. The first suction duct 120 may be sleeved outside the fourth port 141 to communicate with the second three-way joint 140.

In some embodiments, as shown in fig. 3, a first X-ray marker 150 is provided at a location near the drug outlet 112 at the distal end of the tube body 100. The first X-ray mark 150 is a marker that can be detected by an X-ray machine. Alternatively, the first X-ray mark 150 may be formed by an X-ray opaque object. For example, the first X-ray mark 150 may be formed by a metal strip, sheet or layer of platinum iridium alloy, gold, tantalum, or the like. Thus, the position of the first X-ray marker 150 can be detected by the X-ray machine, and the position of the drug port 112 and the insertion position of the distal end of the tube body 100 can be indirectly determined to control the alignment of the drug port 112 with the thrombus or to control the alignment of the first opening 122 at the distal end of the tube body 100 with the thrombus.

Alternatively, the first X-ray marker 150 may include two annular markers, which may encircle the tube body 100, and the two annular markers may be disposed at intervals along the axial direction of the tube body 100, and the drug outlet 112 may be disposed between the two annular markers. For example, a plurality of drug outlets 112 may be arranged in a spiral pattern between two annular marks. In this way, the position of the drug outlet 112 can be accurately determined by the two annular marks.

In particular implementations, the connecting member 410 may take a variety of configurations, and the particular configuration of the connecting member 410 is described in detail below in connection with several particular embodiments.

In some embodiments, the connection part 410 includes a core wire 411, one end of the core wire 411 is connected to the basket 420, and the other end of the core wire 411 can protrude through the second opening, as shown in fig. 4, 5, and 8. The core wire 411 has a simple structure, is easy to implement, and has lower production cost. Alternatively, basket 420 may be configured as an elastic mesh structure that automatically expands after being free of restraint. After the basket 420 is inserted into the suction channel 121, the basket 420 is in a folded state under the constraint of the suction channel 121, the core wire 411 can drive the basket 420 to move until the basket 420 extends out of the first opening 122, the basket 420 is automatically opened after the constraint of the suction channel 121 is removed, and the core wire 411 can drive the basket 420 to move in a blood vessel, such as move, rotate or reciprocate. When it is desired to retract basket 420, a healthcare worker may pull on core wire 411, under the influence of the inner edge of first opening 122, to gradually retract basket 420 and retract into suction channel 121.

In some embodiments, the connection member 410 includes a second suction duct 412, one end of the second suction duct 412 is connected to the basket 420, and the other end of the second suction duct 412 can protrude through the second opening, as shown in fig. 6 and 9. The other end of the second aspiration catheter 412 may be connected to another aspiration device 200, and the other aspiration device 200 may aspirate thrombus through the second aspiration catheter 412 during thrombolysis by injecting thrombolytic drug into the blood vessel through the thrombolysis channel 111, during thrombolysis by shaking the blood vessel through the shaking generator, or during thrombolysis by reciprocating the basket 420, thereby forming a negative pressure region in the affected part and avoiding secondary blockage due to thrombus escape, thus forming double protection. It should be noted that the process of moving, expanding and collapsing the basket 420 by the second suction catheter 412 may be similar to that of the core wire 411, and will not be described herein.

In some embodiments, the connection part 410 may include a receiving duct 413 and a core wire 411 penetrating the receiving duct 413, one end of the core wire 411 extends from one end of the receiving duct 413, the other end of the core wire 411 extends from the other end of the receiving duct 413, the other end of the receiving duct 413 can extend from the second opening, one end of the basket 420 is connected to one end of the receiving duct 413, the other end of the basket 420 is connected to one end of the core wire 411, and the receiving duct 413 and the core wire 411 are used to cooperatively adjust a distance between two ends of the basket 420 to enable the basket 420 to be unfolded or folded, as shown in fig. 7. After the basket 420 extends into the suction channel 121, the basket 420 can be driven to move in the suction channel 121 by the accommodating duct 413 and the core wire 411 together, and after the basket 420 extends out of the first opening 122 of the suction channel 121, the accommodating duct 413 can be kept still, the core wire 411 is pulled in the direction of being separated from the suction channel 121, and the distance between two ends of the basket 420 is reduced, so that the basket 420 is driven to be unfolded. After the operation is finished, the core wire 411 can be pushed in the direction extending into the suction channel 121, so that the distance between the two ends of the basket net is increased, and the basket 420 is driven to be folded. Then, pulling the receiving conduit 413 and the core wire 411 simultaneously can pull the basket 420 in the collapsed state back into the suction channel 121, and finally out of the blood vessel. The connecting component 410 can precisely control the posture of the basket 420, and further precisely control the unfolding position and folding position of the basket 420, and is not limited to the first opening 122. For example, basket 420 may be deployed on the distal side of basket 420 that moves to the thrombus segment. It should be noted that the accommodating duct 413 may also perform a function similar to that of the second suction duct 412, and will not be described here.

In some embodiments, the protective device 400 further comprises a handle 430, the handle 430 being connected to the other end of the core wire 411, the other end of the second suction catheter 412, or the other end of the receiving catheter 413. The setting handle 430 can facilitate the user's operation of the connection part 410. Alternatively, when the connection part 410 includes the core wire 411 or the second suction catheter 412, the protection device 400 may include a handle 430, and the handle 430 may be connected to the other end of the core wire 411 as shown in fig. 4 and 5, and the handle 430 may also be connected to the other end of the second suction catheter 412 as shown in fig. 6. Alternatively, when the connection part 410 includes the core wire 411 and the receiving duct 413, as shown in fig. 7, the protection device 400 may include two handles 430, one handle 430 may be connected to the other end of the receiving duct 413, and the core wire 411 may be inserted through the one handle 430 and connected to the other handle (not shown), so that the core wire 411 and the receiving duct 413 may be moved synchronously or relatively by operating the two handles. Optionally, in order to avoid damage to the location where the second suction catheter 412 engages the handle 430 due to stress, a stress relief sleeve 440 may also be provided between the handle 430 and the second suction catheter 412.

In some embodiments, the basket 420 may be spindle-shaped, the basket 420 having an open end and a closed end opposite the open end, the open end facing the connecting member 410 and being connected to one end of the connecting member 410. In use, basket 420 may be moved to the distal end of the thrombus with the open end of basket 420 facing the thrombus and the thrombus can be removed and allowed to enter basket 420 through the open end. Alternatively, the open end of the basket 420 may be connected to a core wire 411, as shown in FIG. 4. The open end of the basket 420 may also be connected to a second suction conduit 412, as shown in fig. 6. Alternatively, the open end of the basket 420 may be connected to the receiving conduit 413 and the sealed end of the basket 420 may be connected to the core wire 411 as shown in FIG. 7.

In some embodiments, the basket 420 is spindle-shaped, the basket 420 having an open end and a closed end opposite the open end, the closed end facing the connecting member 410 and being connected to one end of the connecting member 410. When in use, the basket 420 can be moved to the far end side of the thrombus section, and in the unfolded state of the basket 420, the meshes from the sealed end to the open end of the basket are gradually reduced, namely, the more close to the falling position of the thrombus, the denser the meshes of the basket 420 are, so that the falling thrombus can be effectively collected, and the thrombus is prevented from escaping. Alternatively, the sealed end of basket 420 may be connected to core wire 411, as shown in FIG. 5. Of course, the basket 420 may also be connected to, for example, the second suction conduit 412 or the receiving conduit 413.

In some embodiments, the basket 420 is flared, the basket 420 having opposite flared ends with a diameter greater than the diameter of the flared ends, the flared ends being connected to one end of the connecting member 410. Alternatively, a portion of basket 420 may be flared. For example, the basket 420 may include a first section, a second section, and a third section connected in sequence, wherein the first section and the third section may each have a cylindrical shape, and the third section has a diameter larger than that of the first section, the second section may be configured to have a horn shape, and one end of the connection part 410 may be connected to the first section, as shown in fig. 8 and 9.

Optionally, the basket 420 may include a multi-layered mesh structure arranged in a stacked manner, so that the density of meshes can be increased, and thus the thrombus collecting efficiency can be improved. Taking the basket 420 as a horn shape as an example, the basket 420 may be a double-layer structure, and the basket 420 in the double-layer structure may be a spindle-shaped net structure in the unfolded state, and one end of the spindle-shaped net structure is turned over to the inside of the basket, so as to form the double-layer and horn-shaped basket 420.

As shown in fig. 4 and 5, in some embodiments, the protection device 400 further includes a second X-ray marker 450, and the second X-ray marker 450 is connected to an end of the basket 420 remote from the connection member 410. The second X-ray marker 450 is also a marker that can be detected using an X-ray machine. For example, the second X-ray marker 450 may be a bar-shaped object, which may be formed by spirally winding a wire, similar to a coil spring. In the operation process, the position of the second X-ray marker 450 can be detected by using an X-ray machine, so that the throwing position of the basket 420 can be indirectly determined, the basket 420 can be ensured to effectively capture thrombus, and the thrombus can be prevented from escaping.

Hereinafter, a practical method of the thrombus aspiration thrombolysis device will be described in detail.

1) The vascular access is established and placed into a vascular sheath, a contrast catheter is placed through the vascular sheath for contrast, and parameters such as the position, the length and the size of thrombus are defined.

2) The distal end of the tube body 100 is placed into a blood vessel through a vascular access, the position of the distal end of the tube body 100 is determined by detecting the first X-ray mark 150 by an X-ray machine until the first opening 122 of the aspiration channel 121 is aligned with the proximal side of the thrombus segment, and the thrombus is aspirated under negative pressure by the aspiration device 200 such as a syringe or an aspiration pump.

3) After the aspiration is finished, contrast agent is input for contrast, and the condition of residual thrombus in the blood vessel is judged. If a large amount of thrombus remains in the blood vessel, the thrombus may be aspirated again.

4) The position of the distal end of the tube body 100 is adjusted, and the position of the first X-ray mark 150 is detected by an X-ray machine in the process until the distal end of the tube body 100 passes through the thrombus segment and the drug outlet 112 is aligned with the residual thrombus.

5) Basket 420 is placed into suction channel 121 through the second opening, basket 420 is pushed forward by connecting member 410 until basket 420 protrudes into the blood vessel through first opening 122, and basket 420 is moved to the distal side of the thrombus segment, switching basket 420 to the deployed state.

6) Thrombolytic drugs are infused into blood vessels through the infusion device 300 to dissolve the thrombus, so that the thrombolytic drugs are ejected out through the drug outlet 112 at a certain pressure and speed to dissolve and break the thrombus. The basket 420 may also be pushed forward or the basket 420 may be retracted backward through the connection member 410, and physical shredding may be performed through the basket 420. The dislodged thrombus can be effectively collected by the basket 420.

6) After thrombolysis and/or thrombolysis is completed, the basket 420 is pulled by the connecting member 410 to retract into the aspiration channel 121 and the captured thrombus is brought together into the aspiration channel 121.

7) Under the detection of the X-ray machine, the whole tube body 100 and the protection device 400 are withdrawn from the body.

The above embodiments are only exemplary embodiments of the present application and are not intended to limit the present application, the scope of which is defined by the claims. Various modifications and equivalent arrangements may be made to the present application by those skilled in the art, which modifications and equivalents are also considered to be within the scope of the present application.

Claims (10)

1. A thrombus aspiration thrombolysis device comprising:

a tube body having a distal end for extending into a blood vessel and a proximal end opposite to the distal end, the interior of the tube body having a suction passage penetrating the distal end and the proximal end and a thrombolysis passage surrounding the suction passage and extending in a longitudinal direction of the tube body, a drug outlet communicating with the thrombolysis passage being provided at a position on the tube body near the distal end, a drug inlet communicating with the thrombolysis passage and a suction port communicating with the suction passage being provided at a position on the tube body near the proximal end, respectively;

a suction device communicating with the suction passage through the suction port for sucking thrombus from a blood vessel through the suction passage;

the infusion device is communicated with the thrombolytic channel through the medicine inlet and is used for injecting thrombolytic medicine into the blood vessel through the thrombolytic channel to perform thrombolysis;

the protecting device comprises a linear connecting part and a basket connected with one end of the connecting part, wherein the connecting part can drive the basket to penetrate through the suction channel and extend out of the first opening of the suction channel at the far end, the other end of the connecting part can extend out of the second opening of the suction channel at the near end, and the basket is used for collecting thrombus.

2. The thrombi aspiration thrombolysis device according to claim 1, wherein said tube body comprises a thrombolysis catheter and a first aspiration catheter penetrating said thrombolysis catheter, a lumen of said first aspiration catheter forming said aspiration channel, a lumen between said thrombolysis catheter and said first aspiration catheter forming said thrombolysis channel.

3. The thrombus aspiration thrombolysis device of claim 2, wherein said tube further comprises a first tee and a second tee;

the first three-way joint is provided with a first interface, a second interface and a third interface, the thrombolysis catheter is connected with the first interface, the first suction catheter extends into the first three-way joint through the first interface, and the third interface forms the medicine inlet;

the second three-way joint is provided with a fourth interface, a fifth interface and a sixth interface, the fourth interface is connected with the first suction catheter through the second interface, the fifth interface forms the second opening, and the sixth interface forms the suction port.

4. The thrombi aspiration thrombolysis device of claim 3, wherein said first port and said second port are in communication via a first connector lumen of a straight shape, said third port being located between said first port and said second port;

the fourth interface is communicated with the fifth interface through a linear second joint inner cavity, and the sixth interface is located between the fourth interface and the fifth interface.

5. The thrombi aspiration thrombolysis protection device of claim 4, wherein a fourth port of said second three-way connector extends into said first connector lumen via said second port and is connected to said first aspiration catheter.

6. The thrombus aspiration thrombolysis device according to claim 1, wherein said connection member comprises a core wire, one end of said core wire being connected to said basket, the other end of said core wire being extendable through said second opening; or (b)

The connecting part comprises a second suction duct, one end of the second suction duct is connected with the basket, and the other end of the second suction duct can extend out through the second opening; or (b)

The connecting component comprises a containing conduit and a core wire penetrating through the containing conduit, one end of the core wire extends out of one end of the containing conduit, the other end of the core wire extends out of the other end of the containing conduit, the other end of the containing conduit can extend out of the second opening, one end of the basket is connected with one end of the containing conduit, the other end of the basket is connected with one end of the core wire, and the containing conduit and the core wire are used for mutually matching and adjusting the distance between two ends of the basket so as to drive the basket to be unfolded or folded.

7. The thrombi aspiration thrombolysis protection device according to claim 6, further comprising a handle connected to the other end of said core wire, the other end of said second aspiration catheter or the other end of said receiving catheter.

8. The thrombi aspiration thrombolysis protection device according to claim 1, wherein said basket is spindle-shaped, said basket having an open end and a sealed end opposite said open end, said open end being directed toward and connected to one end of said connecting member, or said sealed end being directed toward and connected to one end of said connecting member; or (b)

The basket is in a horn shape, the basket is provided with a necking end and a flaring end which are opposite, the diameter of the flaring end is larger than that of the necking end, and the necking end is connected with one end of the connecting component.

9. The thrombi aspiration thrombolysis protection device of claim 1, wherein said basket comprises a multi-layered mesh structure in a stacked arrangement.

10. The thrombus aspiration thrombolysis protection device according to claim 1, wherein a first X-ray mark is provided at a position of the distal end of said tube body close to said drug outlet; and/or

And a second X-ray mark is arranged at one end of the basket away from the connecting part.

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