CN115444509A - Thrombus aspiration thrombolysis protection device - Google Patents

Abstract

The embodiment of the application discloses thrombus suction thrombolysis protection device, it includes: the catheter comprises a catheter body, a suction device, an infusion device and a protection device, wherein the catheter body is provided with a far end used for extending into a blood vessel and a near end opposite to the far end, and a suction channel and a thrombolysis channel are arranged inside the catheter body; an aspiration device communicated with the aspiration channel through the aspiration port for aspirating thrombus from the blood vessel through the aspiration channel; the infusion device is communicated with the thrombolysis channel through the medicine inlet and is used for injecting thrombolysis medicine into the blood vessel through the thrombolysis channel for thrombolysis; the protection device comprises a linear connecting part and a net basket connected with one end of the connecting part, the connecting part can drive the net basket to penetrate through the suction channel and extend out through a first opening of the suction channel at the far end, the other end of the connecting part can extend out through a second opening of the suction channel at the near end, and the net basket is used for collecting thrombus. The device can aspirate thrombi, dissolve thrombi and prevent thrombi from escaping.

Description

Thrombus aspiration thrombolysis protection device

Technical Field

The embodiment of the application relates to the technical field of medical equipment, in particular to a thrombus aspiration thrombolysis protection device.

Background

At present, the treatment method of thrombotic diseases mainly comprises drug conservation treatment and operation treatment, the drug conservation treatment mainly comprises anticoagulation treatment, and aims to reduce mortality, recurrence rate and postthrombotic syndrome, but the anticoagulation treatment has slow effect, is difficult to completely dissolve thrombus and has high bleeding risk. The operation treatment mainly comprises the traditional surgical operation and the endovascular intervention operation treatment, and the vascular incision embolectomy is taken as the traditional surgical operation, so that the traditional clinical operation is basically not adopted due to the defects of large wound, slow postoperative recovery and more complications. With the development of medical imaging technology, intravascular interventional therapy has small trauma, quick recovery and good effect and gradually becomes a main operation mode of thrombotic diseases.

The conventional interventional mechanical thrombus extraction mainly comprises the steps of extending a suction catheter into a blood vessel, performing negative pressure suction on thrombus through the suction catheter, and sucking the thrombus out of the blood vessel so as to reconstruct blood flow in the blood vessel. The interventional mechanical thrombus taking device has the problems that when thrombus is in a narrow blood vessel or the thrombus is stubborn and attached to the blood vessel wall, the effect of the pure negative pressure suction thrombus is very limited, and the operation risk is high. In addition, the thrombus is easy to escape, and blocks other blood vessel branches, so that secondary blockage and other problems are caused.

Disclosure of Invention

In view of the above problems in the prior art, the embodiments of the present application provide a thrombus aspiration and thrombolysis protection device, which can aspirate thrombus, can also deliver thrombolytic drugs into a blood vessel for thrombolysis, and can prevent thrombus from escaping, thereby achieving a good therapeutic effect.

In order to solve the above problems, the embodiments of the present application provide a technical solution that:

a thrombus aspiration thrombolysis protection device comprising:

the catheter body is provided with a far end used for extending into a blood vessel and a near end opposite to the far end, a suction channel and a thrombolytic channel are arranged inside the catheter body, the suction channel penetrates through the far end and the near end, the thrombolytic channel surrounds the suction channel and extends along the length direction of the catheter body, a medicine outlet communicated with the thrombolytic channel is formed in the position, close to the far end, of the catheter body, and a medicine inlet communicated with the thrombolytic channel and a suction inlet communicated with the suction channel are formed in the position, close to the near end, of the catheter body respectively;

an aspiration device communicating with the aspiration channel through the aspiration port for aspirating thrombus from a blood vessel through the aspiration channel;

the infusion device is communicated with the thrombolysis channel through the medicine inlet and is used for injecting thrombolysis medicine into the blood vessel through the thrombolysis channel for thrombolysis;

the protective device comprises a linear connecting component and a net basket connected with one end of the connecting component, the connecting component can drive the net basket to penetrate through the suction channel and extend out through a first opening of the suction channel at the far end, the other end of the connecting component can extend out through a second opening of the suction channel at the near end, and the net basket is used for collecting thrombus.

In some embodiments, the shaft includes a thrombolytic catheter and a first aspiration catheter threaded through the thrombolytic catheter, the lumen of the first aspiration catheter forming the aspiration channel, the lumen between the thrombolytic catheter and the first aspiration catheter forming the thrombolytic channel.

In some embodiments, the body further comprises a first tee fitting and a second tee fitting;

the first three-way joint is provided with a first interface, a second interface and a third interface, the thrombolytic catheter is connected with the first interface, the first suction catheter extends into the first three-way joint through the first interface, and the third interface forms the medicine inlet;

the second three-way joint has a fourth port, a fifth port, and a sixth port, the fourth port is connected with the first suction duct through the second port, the fifth port forms the second opening, and the sixth port forms the suction port.

In some embodiments, the first port and the second port communicate through a linear first connector lumen, and the third port is located between the first port and the second port;

the fourth interface with the fifth interface is communicated through a linear second connector inner cavity, and the sixth interface is located between the fourth interface and the fifth interface.

In some embodiments, the fourth port of the second three-way joint extends into the first joint lumen via the second port and connects with the first aspiration conduit.

In some embodiments, the connecting member comprises a core wire, one end of the core wire is connected with the basket, and the other end of the core wire can protrude through the second opening; or

The connecting part comprises a second suction duct, one end of which is connected with the basket and the other end of which can protrude through the second opening; or

The connecting component comprises an accommodating guide pipe and a core wire penetrating through the accommodating guide pipe, one end of the core wire extends out of one end of the accommodating guide pipe, the other end of the core wire extends out of the other end of the accommodating guide pipe, the other end of the accommodating guide pipe can extend out of the second opening, one end of the basket is connected with one end of the accommodating guide pipe, the other end of the basket is connected with one end of the core wire, and the accommodating guide pipe and the core wire are used for mutually matching to adjust the distance between the two ends of the basket so as to drive the basket to be unfolded or folded.

In some embodiments, the protective device further comprises a handle connected to the other end of the core wire, the other end of the second aspiration conduit, or the other end of the containment conduit.

In some embodiments, the basket is in the shape of a spindle, the basket having an open end and a closed end opposite the open end, the open end being connected to the connecting member and facing the connecting member, or the closed end being connected to the connecting member and facing the connecting member; or

The net basket is trumpet-shaped, the net basket is provided with a reducing end and a flaring end which are opposite, the diameter of the flaring end is larger than that of the reducing end, and the reducing end is connected with one end of the connecting component.

In some embodiments, the basket comprises a multi-layer mesh structure arranged in layers.

In some embodiments, a first X-ray mark is arranged at the position, close to the medicine outlet, of the distal end of the tube body; and/or

And one end of the basket, which is far away from the connecting part, is provided with a second X-ray mark.

The thrombus aspiration and thrombolysis protection device provided by the embodiment of the application can aspirate thrombus from blood vessels, can input thrombolytic drugs into the blood vessels for thrombolysis, can prevent thrombus from escaping, and can form a better treatment effect.

Drawings

Other features, objects and advantages of the present application will become more apparent upon reading of the following detailed description of non-limiting embodiments thereof, made with reference to the accompanying drawings in which:

FIG. 1 is a schematic structural diagram of a thrombus aspiration and thrombolysis protection device according to an embodiment of the present application;

FIG. 2 is a sectional view of a partial structure of a tube body;

FIG. 3 is an enlarged view of a portion of the tube body;

FIG. 4 is a schematic structural diagram of a first embodiment of a protection device;

FIG. 5 is a schematic structural view of a second embodiment of a protective device;

FIG. 6 is a schematic structural view of a third embodiment of the protection device;

FIG. 7 is a schematic structural view of a fourth embodiment of a protective device;

FIG. 8 is a schematic structural view of a fifth embodiment of a protective device;

fig. 9 is a schematic structural diagram of a sixth embodiment of the protection device.

Description of the reference numerals:

100-a tube body; 110-a thrombolytic catheter; 111-thrombolysis channel; 112-medicine outlet; 120-a first aspiration conduit; 121-a suction channel; 122 — a first opening; 130-a first three-way joint; 131-a first interface; 132-a second interface; 133-a third interface; 140-a second three-way joint; 141-fourth interface; 142-a fifth interface; 143-sixth interface; 150-a first X-ray marker;

200-a suction device; 210-an extension tube;

300-an infusion device; 310-a liquid transporter; 320-another extension tube;

400-a protection device; 410-a connecting member; 411-core filament; 412-a second suction duct; 413-a containment conduit; 420-a basket; 430-a handle; 440-a stress relief sleeve; 450-second X-ray marker.

Detailed Description

The present application will be described in further detail with reference to the following drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not to be construed as limiting the invention. It should be noted that, for convenience of description, only the portions related to the present invention are shown in the drawings.

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to the embodiments with reference to the attached drawings.

Referring to fig. 1 to 4, the present application provides a thrombus aspiration and thrombolysis protection device, which includes a tube body 100, an aspiration device 200, an infusion device 300 and a protection device 400.

The shaft 100 has opposite distal and proximal ends, the distal end for extending into a blood vessel. Alternatively, the shaft 100 may be an elongated tubular structure that is capable of extending into a blood vessel, or the shaft 100 may include at least one elongated tubular structure that is capable of extending into a blood vessel. The interior of the shaft 100 has a suction channel 121 and a thrombolysis channel 111, the suction channel 121 extending through the distal and proximal ends, the thrombolysis channel 111 surrounding the suction channel 121 and extending along the length of the shaft 100. Optionally, one end of the thrombolysis channel 111 may extend to a position near the distal end and the other end of the thrombolysis channel 111 may extend to a position near the proximal end.

A medicine outlet 112 is formed in the position, close to the distal end, of the tube body 100, and the medicine outlet 112 can be communicated with the thrombolysis channel 111. Optionally, the tube body 100 may be provided with a plurality of drug outlets 112, and the plurality of drug outlets 112 may be uniformly arranged at a position on the tube body 100 near the distal end, so as to uniformly output thrombolytic drugs into the blood vessel. For example, the plurality of drug outlets 112 may be uniformly arranged at equal intervals along the axial direction of the tube body 100, at equal intervals along the circumferential direction of the tube body 100, or may be spirally arranged along the tube body 100. In practice, the drug outlet 112 may take various shapes, for example, the drug outlet 112 may be a circular hole, a strip-shaped hole or another shaped hole. A medicine inlet and a suction inlet are respectively formed in the tube body 100 at positions close to the proximal end, the medicine inlet is communicated with the thrombolysis channel 111, and the suction inlet is communicated with the suction channel 121.

The suction device 200 communicates with the suction channel 121 through the suction port for sucking thrombus from the blood vessel through the suction channel 121. In practice, the suction device 200 can be any device capable of providing suction power. Alternatively, the aspiration device 200 may be a manual aspiration device 200, such as a manual negative pressure pump or syringe, or the like. The suction device 200 may also employ an automatic suction device 200, such as a hydraulic pump or an electric negative pressure pump, or the like. Optionally, the suction device 200 may be connected to the suction port through an extension tube 210, so that the surgical space may be expanded, and the medical staff may operate the suction device 200 conveniently.

The infusion device 300 is communicated with the thrombolysis channel 111 through the medicine inlet and is used for injecting thrombolysis medicine into the blood vessel through the thrombolysis channel 111 for thrombolysis. In practice, the infusion device 300 may be any of a variety of devices capable of delivering a medical fluid into the thrombolytic passage 111. Alternatively, the infusion device 300 may be a manual infusion device 300. For example, the infusion device 300 may include a syringe. Also for example, the infusion device 300 can include a liquid delivery device 310 and a syringe (not shown), the liquid delivery device 310 can be connected to the drug inlet, the syringe containing the thrombolytic drug can be mounted to the liquid delivery device 310, and a health care provider can deliver the thrombolytic drug in the syringe to the thrombolytic passage 111 by squeezing the handle 430 of the liquid delivery device 310 and deliver the thrombolytic drug to the blood vessel through the thrombolytic passage 111. Alternatively, the infusion device 300 may be an automatic infusion device 300. For example, the infusion device 300 may be an infusion pump capable of automatic infusion. Optionally, the infusion device 300 may further include a vibration generator that may transmit vibrations into the blood vessel through the thrombolytic drug in the thrombolytic channel 111 to assist in the thrombolysis. Optionally, the infusion device 300 may be connected to the drug inlet via another extension tube 320 to expand the surgical space and facilitate the medical staff to operate the infusion device 300.

The protection device 400 comprises a connecting part 410 and a basket 420, the connecting part 410 may be in a wire shape, one end of the connecting part 410 may be connected with the basket 420, the connecting part 410 is used for driving the basket 420 to penetrate through the suction channel 121 and extend out through the first opening 122 of the suction channel 121 at the distal end, the other end of the connecting part 410 can extend out through the second opening of the suction channel 121 at the proximal end, and the basket 420 is used for collecting thrombus. That is, the basket 420 may extend into the suction channel 121 through the second opening, and the basket 420 may extend through the second opening by the driving of the connecting member 410.

According to the thrombus aspiration and thrombolysis protection device provided by the embodiment of the application, the tube body 100 can be input into a blood vessel of a patient, and the inside of the tube body 100 is provided with an aspiration channel 121 and a thrombolysis channel 111; the suction device 200 is connected to the suction channel 121 through a suction port, and the thrombus can be sucked from the blood vessel through the suction channel 121; the infusion device 300 is connected with the thrombolysis channel 111 through the medicine inlet, and the infusion device 300 can input thrombolytic medicines into the blood vessel through the thrombolysis channel 111 for thrombolysis; the protection device 400 comprises a connecting part 410 and a basket 420, and the basket 420 can be driven by the connecting part 410 to extend into a blood vessel through the suction channel 121 so as to collect thrombus and avoid secondary blockage caused by escape of the thrombus. For example, during thrombolysis or aspiration, the basket 420 may be placed on the distal side of the thrombus segment to prevent thrombus from escaping during thrombolysis or aspiration. Therefore, the thrombus aspiration and thrombolysis protection device can aspirate thrombus from blood vessels, can also input thrombolytic drugs into the blood vessels for thrombolysis, can prevent the thrombus from escaping, and can form a better treatment effect.

As shown in fig. 2, in some embodiments, the catheter body 100 includes a thrombolytic catheter 110 and a first aspiration catheter 120 penetrating the thrombolytic catheter 110, wherein a lumen of the first aspiration catheter 120 forms the aspiration channel 121, and a lumen between the thrombolytic catheter 110 and the first aspiration catheter 120 forms the thrombolytic channel 111. The thrombolysis catheter 110 and the first suction catheter 120 which are nested inside and outside form the catheter body 100, which is beneficial to reducing the diameter of the catheter body 100, so that the catheter body 100 can extend into a blood vessel with a smaller diameter, and the application scene of the thrombolysis suction protection device is expanded.

Alternatively, one end of the thrombolysis catheter 110 may extend to a position near the distal end of the shaft 100, that is, to a position near one end of the first aspiration catheter 120, and one end of the thrombolysis catheter 110 may be fixedly connected to the outer wall of the first aspiration catheter 120 through a constriction and close an end-face opening of the thrombolysis channel 111. The other end of the thrombolysis conduit 110 may extend to a position close to the other end of the first suction conduit 120, and the other end of the thrombolysis conduit 110 may also be fixedly connected to the outer wall of the first suction conduit 120 to close the other end face opening of the thrombolysis channel 111. The drug inlet can be opened on the side wall of the thrombolysis catheter 110 to facilitate the medical staff to operate the infusion device 300, and is also easy to realize.

Alternatively, the suction port may be opened at a sidewall of the first suction catheter 120 to facilitate the medical staff's operation. In some cases, the suction port may also be the same opening as the second opening. For example, both the suction port and the second opening may be formed by the proximal end face opening of the first suction catheter 120.

In some embodiments, the body 100 further includes a first tee fitting 130 and a second tee fitting 140. The first three-way joint 130 has a first interface 131, a second interface 132 and a third interface 133, the thrombolytic conduit 110 is connected to the first interface 131, the first suction conduit 120 extends into the first three-way joint 130 through the first interface 131, and the third interface 133 forms the drug inlet. The second three-way joint 140 has a fourth port 141, a fifth port 142 and a sixth port, the fourth port 141 being connected with the first suction duct 120 via the second port 132, the fifth port 142 forming the second opening and the sixth port forming the suction opening. The connection of the suction device 200 and the infusion set 300 to the tube body 100 can be facilitated by providing the first three-way joint 130 and the second three-way joint 140.

Optionally, the first port 131 and the second port 132 are communicated through a linear first joint inner cavity, and the third port 133 is located between the first port 131 and the second port 132; the fourth port 141 and the fifth port 142 are communicated through a linear second joint inner cavity, and the sixth port is located between the fourth port 141 and the fifth port 142. In fact, the suction channel 121 is formed by the lumen of the first suction catheter 120 and the first connector lumen, and the formed suction channel 121 extends along the length direction of the tube body 100 without a distinct bending part, so that the mesh basket 420 and the connecting component 410 can be inserted into the suction channel 121 and pushed into the suction channel 121, thereby facilitating the operation of the medical staff.

Optionally, the fourth port 141 of the second three-way joint 140 extends into the first joint lumen via the second port 132 and is connected to the first suction conduit 120. That is, the fourth port 141 of the second three-way joint 140 extends into the first joint lumen and is directly connected to the first suction conduit 120. So, need not to set up switching structure in the first joint inner chamber, be of value to simplifying the inner structure of first three way connection 130, still be of value to improving the leakproofness, can reduction in production cost.

Optionally, the first joint inner cavity may include a first cavity section and a second cavity section, the first interface 131 is disposed at one end of the first cavity section, the other end of the first cavity section is connected to the second cavity section, the other end of the second cavity section is provided with a second interface 132, and the third interface 133 may be opened on a side wall of the first cavity section. The first segment may be cylindrical, and the diameter of the second segment may gradually decrease from the second port 132 to the first port 131. The thrombolysis conduit 110 may extend into the first lumen segment via the first port 131 to a position adjacent the third port 133, and the first aspiration conduit 120 may extend into the first lumen segment via the first opening 122 to a position where the first lumen segment and the second lumen segment meet. The second tee fitting 140 may be provided through the second chamber section and the fourth port 141 extends into the first chamber section and connects to the first suction conduit 120. Optionally, the outer wall of the second tee 140 may conform to the inner wall of the second chamber section to effect a seal. The first suction conduit 120 may be sleeved outside the fourth port 141 to communicate with the second three-way joint 140.

In some embodiments, as shown in fig. 3, a first X-ray marker 150 is disposed at a position near the drug outlet 112 at the distal end of the tube body 100. The first X-ray marker 150 is a marker that can be detected by an X-ray machine. Alternatively, the first X-ray marker 150 may be formed by an object that is opaque to X-rays. For example, the first X-ray marker 150 may be formed by a metal strip, sheet or layer of platinum-iridium alloy, gold, tantalum, or the like. Thus, the position of the first X-ray mark 150 can be detected by the X-ray machine, and the position of the drug outlet 112 and the insertion position of the distal end of the tube body 100 can be indirectly determined, so as to control the drug outlet 112 to be aligned with the thrombus, or control the first opening 122 at the distal end of the tube body 100 to be aligned with the thrombus.

Alternatively, the first X-ray marker 150 may include two ring markers, the ring markers may surround the tube body 100, the two ring markers may be spaced apart along the axial direction of the tube body 100, and the drug outlet 112 may be disposed between the two ring markers. For example, a plurality of drug outlets 112 may be arranged in a spiral shape between two ring-shaped marks. Thus, the position of the medicine port 112 can be accurately determined through the two annular marks.

In practice, the connecting member 410 may have various structures, and the specific structure of the connecting member 410 will be described in detail with reference to several specific embodiments.

In some embodiments, the connecting member 410 includes a core wire 411, one end of the core wire 411 is connected to the basket 420, and the other end of the core wire 411 can protrude through the second opening, as shown in fig. 4, 5 and 8. The core wire 411 has a simple structure, is easy to implement, and has a low production cost. Alternatively, the basket 420 may be constructed as a flexible mesh structure that automatically expands upon being unbounded. After the basket 420 is inserted into the suction passage 121, the basket 420 is in a folded state under the constraint of the suction passage 121, the basket 420 can be driven to move by the core wire 411 until the basket 420 extends out of the first opening 122, after the constraint of the suction passage 121 is removed, the basket 420 is automatically opened, and the core wire 411 can drive the basket 420 to move, such as move, rotate or reciprocate and the like, in the blood vessel. When it is desired to withdraw the basket 420, the medical staff may pull the core wire 411, and the basket 420 is gradually gathered by the inner edge of the first opening 122 and retracted into the suction passage 121.

In some embodiments, the connecting member 410 includes a second suction duct 412, one end of the second suction duct 412 is connected to the basket 420, and the other end of the second suction duct 412 can protrude through the second opening, as shown in fig. 6 and 9. The other end of the second suction catheter 412 can be connected with another suction device 200, and in the process of injecting thrombolytic drugs into the blood vessel through the thrombolytic channel 111 for thrombolysis, or in the process of breaking thrombus through vibration generated by the vibration generator, or in the process of breaking thrombus through reciprocating motion of the basket 420, the another suction device 200 can suck thrombus through the second suction catheter 412 to form a negative pressure region at the affected part, so that secondary blockage caused by escape of the thrombus is avoided, and double protection is formed. It should be noted that the process of moving, unfolding and folding the basket 420 by the second suction duct 412 can be similar to that of the core wire 411, and the description thereof is omitted.

In some embodiments, the connecting component 410 may include a receiving conduit 413 and a core wire 411 disposed through the receiving conduit 413, one end of the core wire 411 extends from one end of the receiving conduit 413, the other end of the core wire 411 extends from the other end of the receiving conduit 413, the other end of the receiving conduit 413 can extend from the second opening, one end of the basket 420 is connected to one end of the receiving conduit 413, the other end of the basket 420 is connected to one end of the core wire 411, and the receiving conduit 413 and the core wire 411 are configured to cooperate with each other to adjust a distance between two ends of the basket 420, so as to drive the basket 420 to unfold or fold, as shown in fig. 7. After the basket 420 extends into the suction channel 121, the basket 420 can be driven to move in the suction channel 121 by the accommodating conduit 413 and the core wire 411, after the basket 420 extends out of the first opening 122 of the suction channel 121, the accommodating conduit 413 can be kept still, the core wire 411 is pulled in the direction of being pulled out of the suction channel 121, the distance between the two ends of the basket 420 is reduced, and the basket 420 is driven to be unfolded. After the operation is finished, the core wire 411 may be pushed in the direction of extending into the suction channel 121, so as to increase the distance between the two ends of the basket net, thereby driving the basket 420 to be folded. Then, the simultaneous pulling of the receiving tube 413 and the core wire 411 can pull the net basket 420 in the collapsed state back into the suction channel 121, and finally out of the blood vessel. The connecting component 410 can precisely control the posture of the basket 420, and further precisely control the unfolding position and the folding position of the basket 420, and is not limited to the first opening 122. For example, the basket 420 may be deployed on the distal side of the basket 420 that moves to the thrombus segment. It should be noted that the accommodating duct 413 can also perform a function similar to that of the second suction duct 412, and therefore, the description thereof is omitted.

In some embodiments, the protection device 400 further comprises a handle 430, and the handle 430 is connected to the other end of the core wire 411, the other end of the second suction duct 412 or the other end of the housing duct 413. The handle 430 is provided to facilitate user manipulation of the connection member 410. Alternatively, when the connection member 410 includes the core wire 411 or the second suction duct 412, the protector 400 may include a handle 430, and the handle 430 may be connected to the other end of the core wire 411, as shown in fig. 4 and 5, and the handle 430 may also be connected to the other end of the second suction duct 412, as shown in fig. 6. Alternatively, when the connecting member 410 includes the core wire 411 and the accommodating duct 413, as shown in fig. 7, the protection device 400 may include two handles 430, one handle 430 may be connected to the other end of the accommodating duct 413, the core wire 411 may be passed through the one handle 430 and connected to the other handle (not shown), and the core wire 411 and the accommodating duct 413 may be moved synchronously or displaced relatively by operating the two handles. Optionally, a strain relief sleeve 440 may also be provided between the handle 430 and the second suction conduit 412 to avoid damage to the second suction conduit 412 where it engages the handle 430 due to strain.

In some embodiments, the basket 420 may be in the shape of a spindle, and the basket 420 has an open end facing the link 410 and connected to one end of the link 410 and a closed end opposite to the open end. In use, the basket 420 may be moved to the distal end of the thrombus with the open end of the basket 420 facing the thrombus, and the thrombus may enter the basket 420 through the open end after sloughing off. Alternatively, the open end of the basket 420 may be connected to the core wire 411, as shown in fig. 4. The open end of the basket 420 may also be connected to a second suction duct 412, as shown in fig. 6. Alternatively, the open end of the basket 420 may be connected to the receiving conduit 413 and the closed end of the basket 420 may be connected to the core wire 411, as shown in fig. 7.

In some embodiments, the basket 420 has a spindle shape, and the basket 420 has an open end and a closed end opposite to the open end, the closed end facing the link 410 and being connected to one end of the link 410. During the use, can remove basket 420 to the distal end side of thrombus section, under basket 420 expandes the state, dwindles gradually from its sealing end to its opening end mesh, promptly, is close to the position that drops of thrombus more, and basket 420's mesh is intensive more, can effectually collect the thrombus that drops, avoids the thrombus to escape. Alternatively, the closed end of the basket 420 may be connected to the core wire 411, as shown in fig. 5. Of course, the basket 420 may also be connected to, for example, the second suction duct 412 or the receiving duct 413.

In some embodiments, the basket 420 is flared, the basket 420 having opposite flared and flared ends, the flared end having a diameter greater than the diameter of the flared end, the flared end being coupled to an end of the coupling member 410. Alternatively, a portion of the basket 420 may be flared. For example, the basket 420 may include a first section, a second section, and a third section connected in sequence, wherein the first section and the third section may each have a cylindrical shape, and the third section has a diameter greater than that of the first section, the second section may be configured to have a trumpet shape, and one end of the connecting member 410 may be connected to the first section, as shown in fig. 8 and 9.

Optionally, the basket 420 may include a plurality of layers of mesh structures arranged in a stacked manner, so that the density of mesh openings can be increased, and the thrombus collection efficiency can be improved. Taking the basket 420 as a trumpet-shaped basket as an example, the basket 420 may be an integrated double-layer structure, and the basket 420 of the double-layer structure may be a spindle-shaped net structure in an unfolded state, and one end of the spindle-shaped net structure is turned over toward the inside of the spindle-shaped net structure, so as to form the double-layer trumpet-shaped basket 420.

In some embodiments, as shown in fig. 4 and 5, the protecting device 400 further includes a second X-ray marker 450, and the second X-ray marker 450 is connected to an end of the basket 420 far from the connecting member 410. The second X-ray marker 450 is also a marker that can be detected by an X-ray machine. For example, the second X-ray marker 450 may be a strip-shaped object, which may be formed by a wire spirally wound, similar to a coil spring. In the operation process, the position of the second X-ray marker 450 can be detected by an X-ray machine, so that the throwing position of the basket 420 can be indirectly determined, the basket 420 can be ensured to effectively capture thrombus, and the thrombus is prevented from escaping.

The practical method of the thrombus aspiration and thrombolysis protector will be described in detail below.

1) Establishing a blood vessel passage, placing a blood vessel sheath, placing a contrast catheter through the blood vessel sheath for contrast, and determining the position, the length, the size and other parameters of the thrombus.

2) The distal end of the shaft 100 is inserted into the blood vessel through the blood vessel access, the first X-ray marker 150 is detected by the X-ray machine to determine the position of the distal end of the shaft 100 until the first opening 122 of the aspiration channel 121 is aligned with the proximal side of the thrombus segment, and the thrombus is aspirated under negative pressure by an aspiration device 200, such as a syringe or an aspiration pump.

3) After the aspiration is finished, contrast agent is input for contrast, and the condition of thrombus remained in the blood vessel is judged. If a large amount of thrombus still remains in the vessel, the thrombus can be aspirated again.

4) The position of the distal end of the tube body 100 is adjusted, and the position of the first X-ray mark 150 is detected by the X-ray machine in the process until the distal end of the tube body 100 passes through the thrombus section, and the medicine outlet 112 is aligned with the residual thrombus.

5) The basket 420 is placed into the aspiration channel 121 through the second opening, and the basket 420 is pushed forward by the connecting member 410 until the basket 420 is inserted into the blood vessel through the first opening 122 and the basket 420 is moved to the distal side of the thrombus segment, so that the basket 420 is switched to the deployed state.

6) The infusion device 300 is used for inputting thrombolytic drugs into the blood vessel for thrombolysis, so that the thrombolytic drugs are ejected from the drug outlet 112 at a certain pressure and speed for thrombolysis and thrombolysis. Physical fragmentation can also be performed by the basket 420 by pushing the basket 420 forward or retracting the basket 420 backward through the link member 410. The dislodged thrombus can be effectively collected by the basket 420.

6) After thrombolysis and/or thrombolysis is completed, the basket 420 is pulled by the connecting member 410 to be withdrawn into the suction passage 121 and to bring the captured thrombus together into the suction passage 121.

7) Under the detection of an X-ray machine, the tube body 100 and the protection device 400 are integrally withdrawn from the body.

The above embodiments are only exemplary embodiments of the present application, and are not intended to limit the present application, and the protection scope of the present application is defined by the claims. Various modifications and equivalents may be made by those skilled in the art within the spirit and scope of the present application and such modifications and equivalents should also be considered to be within the scope of the present application.

Claims (10)

1. A thrombus aspiration thrombolysis protection device, comprising:

the catheter body is provided with a far end used for extending into a blood vessel and a near end opposite to the far end, a suction channel and a thrombolytic channel are arranged inside the catheter body, the suction channel penetrates through the far end and the near end, the thrombolytic channel surrounds the suction channel and extends along the length direction of the catheter body, a medicine outlet communicated with the thrombolytic channel is formed in the position, close to the far end, of the catheter body, and a medicine inlet communicated with the thrombolytic channel and a suction inlet communicated with the suction channel are formed in the position, close to the near end, of the catheter body respectively;

an aspiration device communicating with the aspiration channel through the aspiration port for aspirating thrombus from the blood vessel through the aspiration channel;

the infusion device is communicated with the thrombolysis channel through the medicine inlet and is used for injecting thrombolysis medicine into the blood vessel through the thrombolysis channel for thrombolysis;

the protective device comprises a linear connecting component and a net basket connected with one end of the connecting component, the connecting component can drive the net basket to penetrate through the suction channel and extend out through a first opening of the suction channel at the far end, the other end of the connecting component can extend out through a second opening of the suction channel at the near end, and the net basket is used for collecting thrombus.

2. The thrombus aspiration thrombolysis protection device of claim 1, wherein the shaft comprises a thrombolysis catheter and a first aspiration catheter threaded through the thrombolysis catheter, wherein a lumen of the first aspiration catheter forms the aspiration channel, and wherein a lumen between the thrombolysis catheter and the first aspiration catheter forms the thrombolysis channel.

3. The thrombectomy protection device of claim 2, wherein said body further comprises a first tee fitting and a second tee fitting;

the first three-way joint is provided with a first interface, a second interface and a third interface, the thrombolytic catheter is connected with the first interface, the first suction catheter extends into the first three-way joint through the first interface, and the third interface forms the medicine inlet;

the second three-way joint has a fourth port connected with the first suction duct through the second port, a fifth port forming the second opening, and a sixth port forming the suction port.

4. The thrombus aspiration thrombolysis protection device of claim 3, wherein the first port and the second port communicate via a first linear connector lumen, and the third port is located between the first port and the second port;

the fourth interface and the fifth interface are communicated through a linear second connector inner cavity, and the sixth interface is located between the fourth interface and the fifth interface.

5. The thrombectomy protection device of claim 4, wherein the fourth port of the second tee connector extends into the first connector lumen via the second port and is connected to the first aspiration catheter.

6. The thrombectomy protection device of claim 1, wherein the connecting member comprises a core wire, one end of the core wire is connected to the basket, and the other end of the core wire is capable of protruding through the second opening; or

The connecting part comprises a second suction duct, one end of which is connected with the basket and the other end of which can protrude through the second opening; or

The connecting component comprises an accommodating conduit and a core wire penetrating through the accommodating conduit, one end of the core wire extends out of one end of the accommodating conduit, the other end of the core wire extends out of the other end of the accommodating conduit, the other end of the accommodating conduit can extend out of the second opening, one end of the basket is connected with one end of the accommodating conduit, the other end of the basket is connected with one end of the core wire, and the accommodating conduit and the core wire are used for mutually matching to adjust the distance between the two ends of the basket so as to drive the basket to be unfolded or folded.

7. The thrombectomy protection device of claim 6, further comprising a handle connected to the other end of the core wire, the other end of the second aspiration catheter or the other end of the containment catheter.

8. The thrombus aspiration thrombolysis protection device according to claim 1, wherein the basket is in the form of a spindle having an open end and a closed end opposite to the open end, the open end being toward the coupling member and coupled to one end of the coupling member, or the closed end being toward the coupling member and coupled to one end of the coupling member; or

The net basket is trumpet-shaped, the net basket is provided with a reducing end and a flaring end which are opposite, the diameter of the flaring end is larger than that of the reducing end, and the reducing end is connected with one end of the connecting component.

9. The thrombectomy protection device of claim 1, wherein the basket comprises a multi-layered mesh structure disposed in a stack.

10. The thrombus aspiration thrombolysis protection device according to claim 1, wherein a first X-ray mark is arranged at a position close to the drug outlet at the distal end of the tube body; and/or

And one end of the basket, which is far away from the connecting part, is provided with a second X-ray mark.

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