CN219065491U

CN219065491U - 384 micro-pore plate sample loading auxiliary device

Info

Publication number: CN219065491U
Application number: CN202221665086.6U
Authority: CN
Inventors: 张燕妮; 吴国豪; 隋翔宇; 丁佐佑
Original assignee: Zhongshan Hospital Fudan University
Current assignee: Zhongshan Hospital Fudan University
Priority date: 2022-06-29
Filing date: 2022-06-29
Publication date: 2023-05-23
Anticipated expiration: 2032-06-29

Abstract

The utility model belongs to the technical field of biological test equipment, and discloses a 384-micro-pore plate sample loading auxiliary device. The 384-micropore plate sample loading auxiliary device comprises a box body, an indication strip and a plurality of marking keys, wherein the box body is of a cuboid structure and is provided with a containing bin for containing 384-micropore plates; the indication strip is selectively arranged on the upper surface of the box body and is used for marking the 384-micro-plate in a partitioning way; the marking keys are arranged in one-to-one correspondence with the micropores of the 384-micropore plate, each marking key comprises a first marking key and a second marking key, the first marking key is arranged on the outer peripheral surface of the box body in the length direction, the second marking key is arranged on the outer peripheral surface of the box body in the width direction, and the marking keys can be pressed to mark the micropores. The 384-micropore plate loading auxiliary device provided by the utility model can accurately determine the micropore position and prevent missing or wrong loading in the loading process.

Description

384 micro-pore plate sample loading auxiliary device

Technical Field

The utility model relates to the technical field of biological test equipment, in particular to a 384-micro-pore plate sample loading auxiliary device.

Background

The porous plate is a cell biology experimental device, has wide application in experiments such as cell culture, fluorescence/chemiluminescence detection, drug screening and the like, is more than 96-well plates and 384-well plates, has more sample holes and denser distribution of the 96-well plates and the 384-well plates, has small hole-to-hole distance, has no obvious mark, is difficult to identify in the row and column of the holes in the experimental process, and is easy to cause the conditions of wrong addition and missing addition in the sample adding process by operators, thereby influencing the accuracy of experimental results.

In the prior art, an LED indicator lamp is often used to mark a hole site to be sampled, however, in the field of medical science, a Polymerase Chain Reaction (PCR) method is often used to detect a sample for the change of gene level, because the PCR fluorescent dye is quenched under the irradiation of light, light shielding should be paid attention to as much as possible in order to slow down the fluorescence quenching, and 384 micro-well plates are often needed to be used when the PCR method detects the sample, the hole pitch of 384 holes is smaller, and the situation of misaddition and missed addition is more likely to occur, so that a new auxiliary device is needed to be provided to solve the problems.

Disclosure of Invention

The utility model aims to provide a 384-micro-well plate loading auxiliary device, which aims to prevent missing or wrong loading during loading.

To achieve the purpose, the utility model adopts the following technical scheme:

a 384 microwell plate loading aid, comprising:

the box body is of a cuboid structure and is provided with a containing bin, and the containing bin is used for containing the 384-micro-pore plates;

the indication strip is selectively arranged on the upper surface of the box body and is used for marking the 384-micro-plate in a partitioning manner;

the marking keys are arranged in one-to-one correspondence with the micropores of the 384-micropore plate, each marking key comprises a first marking key and a second marking key, the first marking key is arranged on the outer peripheral surface of the box body in the length direction, the second marking key is arranged on the outer peripheral surface of the box body in the width direction, and the marking keys can be pressed to mark the micropores.

Optionally, the size of the receiving bin matches the size of the 384 microwell plate.

Optionally, the indicator strip includes a first indicator strip and a second indicator strip, the first indicator strip is disposed along a length direction of the box body, and the second indicator strip is disposed along a width direction of the box body.

Optionally, the box body is last to be equipped with the card solid groove, the card solid groove encloses to be located the week side in holding storehouse, and follows the depth direction in holding storehouse extends, the both ends of instruction strip all are equipped with the portion of bending, the portion of bending can insert in the card solid groove.

Optionally, the first marking key is provided with a number identifier from 1 to 24, and the second marking key is provided with a letter identifier from a to P.

Optionally, the first mark key and/or the second mark key comprises a pressing piece and a fixing piece which are connected in a rotating way, the fixing piece is connected with the box body, the pressing piece is provided with an elastic buckle, the first mark key and/or the second mark key is configured to press the pressing piece, and the pressing piece can rotate relative to the fixing piece and enable the elastic buckle of the pressing piece to be clamped with the fixing piece.

Optionally, the pressing piece is provided with a side plate, and the elastic buckle is arranged on the inner side surface of the side plate.

Optionally, a supporting frame is connected between the pressing piece and the fixing piece.

Optionally, the support frame includes first connecting rod and the second connecting rod that connects through the elastic component, the tip of first connecting rod with press piece fixed connection, the tip of second connecting rod with mounting fixed connection.

Optionally, the elastic element is a spring.

The utility model has the beneficial effects that: according to the 384-micro-hole plate sample loading auxiliary device provided by the utility model, when samples comprise different groups, the indication strips can be arranged on the upper surface of the box body, and the indication strips can divide the sample loading areas of the 384-micro-hole plates so as to prevent the samples of different groups from being added with the positions, and when the samples are of the same group, the indication strips can be omitted; in the sample adding process, when the sight line of an operator leaves the micro-pore plate, the last sample adding position can be marked by pressing a marking key, and when the sample is added again, the next sample adding hole can be rapidly positioned to prevent missing or excessive addition; the outer peripheral surface of the length direction of the box body is provided with a first marking key, the outer peripheral surface of the width direction of the box body is provided with a second marking key, and when in marking, the first marking key and the second marking key corresponding to the micropores are pressed simultaneously so as to accurately position the micropores, accurately determine the positions of the micropores and improve the sample adding efficiency.

Drawings

FIG. 1 is a schematic diagram of a 384-well plate according to an embodiment of the present utility model;

FIG. 2 is a schematic diagram of a 384-well plate loading auxiliary device according to an embodiment of the present utility model;

fig. 3 is a schematic structural diagram of a marking key according to an embodiment of the present utility model.

In the figure:

1. a case body; 11. a storage bin; 12. a clamping groove; 2. 384 microwell plates; 3. an indicator bar; 31. a first indicator strip; 32. a second indicator bar; 4. marking keys; 41. a first marking key; 411. a pressing member; 4111. a side plate; 412. a fixing member; 4131. a first link; 4132. an elastic member; 4133. a second link; 42. and a second marking key.

Detailed Description

The utility model is described in further detail below with reference to the drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the utility model and are not limiting thereof. It should be further noted that, for convenience of description, only some, but not all of the structures related to the present utility model are shown in the drawings.

In the description of the present utility model, unless explicitly stated and limited otherwise, the terms "connected," "connected," and "fixed" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present utility model will be understood in specific cases by those of ordinary skill in the art.

In the present utility model, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature.

In the description of the present embodiment, the terms "upper", "lower", "right", etc. orientation or positional relationship are based on the orientation or positional relationship shown in the drawings, and are merely for convenience of description and simplicity of operation, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the utility model. Furthermore, the terms "first," "second," and the like, are used merely for distinguishing between descriptions and not for distinguishing between them.

As shown in fig. 1 and 2, the present embodiment provides a 384-micro-well plate loading auxiliary device, where the 384-micro-well plate loading auxiliary device includes a box body 1, an indicator strip 3 and a plurality of marking keys 4, the box body 1 is in a cuboid structure, the box body 1 has a receiving bin 11, and the receiving bin 11 is used for receiving a 384-micro-well plate 2; the indication strip 3 is optionally arranged on the upper surface of the box body 1, and the indication strip 3 is used for marking the 384 micro-plates 2 in a partitioning way; the marking keys are arranged in one-to-one correspondence with the micro holes of the 384 micro-hole plate 2, the marking keys 4 comprise first marking keys 41 and second marking keys 42, the first marking keys 41 are arranged on the outer peripheral surface of the box body 1 in the length direction, the second marking keys 42 are arranged on the outer peripheral surface of the box body 1 in the width direction, and the micro holes can be marked by pressing the marking keys 4.

According to the 384-micro-hole plate sample loading auxiliary device provided by the utility model, when samples comprise different groups, the indication strip 3 can be arranged on the upper surface of the box body 1, the indication strip 3 can divide the sample loading area of the 384-micro-hole plate 2 so as to prevent the samples of the different groups from being added with the offset, and when the samples are of the same group, the indication strip 3 can be omitted; in the sample adding process, when the sight line of an operator leaves the micro-pore plate, the last sample adding position can be marked by pressing the marking key 4, and when the sample is added again, the next sample adding hole can be rapidly positioned to prevent missing or excessive addition; the outer peripheral surface of the length direction of the box body 1 is provided with a first marking key 41, the outer peripheral surface of the width direction of the box body 1 is provided with a second marking key 42, and when in marking, the first marking key 41 and the second marking key 42 corresponding to the micropore are pressed simultaneously so as to accurately position the micropore, accurately determine the micropore position and improve the sample adding efficiency.

Optionally, the size of the accommodating bin 11 is matched with the size of the 384-micro-pore plate 2, so that the 384-micro-pore plate 2 is prevented from shaking in the accommodating bin 11, and the use reliability of the auxiliary device is improved.

In the present embodiment, the indicator 3 includes a first indicator 31 and a second indicator 32, the first indicator 31 is disposed along the length direction of the case 1, and the second indicator 32 is disposed along the width direction of the case 1. When the groups of samples are four groups, the indicator strips 3 can be arranged in the length and width directions of the box body 1 so as to accurately divide four sample adding areas and prevent error adding.

Further, be equipped with card solid groove 12 on the box body 1, card solid groove 12 encloses the week side of locating holding storehouse 11, and extends along the depth direction of holding storehouse 11, and the both ends of instruction strip 3 all are equipped with the portion of bending, and the portion of bending can insert card solid inslot 12, and card solid groove 12 can prevent effectively that instruction strip 3 from droing.

Preferably, the longitudinal section of the accommodating bin 11 is in an inverted trapezoid shape, so that 384 micro-plates 2 can enter the bin opening of the accommodating bin 11.

Preferably, the locking groove 12 has a slope, and the slope of the locking groove 12 is equal to the slope of the side wall of the corresponding accommodating bin 11, so as to prevent the bending part of the indicator strip 3 from being separated from the locking groove 12 after being inserted into the locking groove 12.

Alternatively, the first index key 41 is provided with the numerical designations of numerals 1 to 24 and the second index key 42 is provided with the letter designations of letters a to P.

In this embodiment, as shown in fig. 3, the first marking key 41 and/or the second marking key 42 includes a pressing member 411 and a fixing member 412 that are rotatably connected, the fixing member 412 is connected to the case 1, the pressing member 411 is provided with an elastic buckle (not shown in the drawing), and the first marking key 41 and/or the second marking key 42 is configured to press the pressing member 411, and the pressing member 411 can rotate relative to the fixing member 412 and enable the elastic buckle of the pressing member 411 to be clamped to the fixing member 412. When the sample is marked, the sample can be marked simply and quickly by only pressing the corresponding first marking key 41 and/or second marking key 42.

Illustratively, the pressing member 411 and the fixing member 412 are rotatably connected by a rotation shaft, the structure is simple, and the pressing member 411 and the fixing member 412 have good rotation reliability.

Optionally, the pressing piece 411 is provided with a side plate 4111, and elastic buckles are disposed on an inner side surface of the side plate 4111, so as to prevent adjacent first mark keys 41 or second mark keys 42 from affecting each other when pressing the mark, and improve the marking efficiency.

Further, a supporting frame is connected between the pressing member 411 and the fixing member 412. By providing the supporting frame, the supporting effect of the fixing member 412 on the pressing member 411 is ensured.

Specifically, the support frame includes a first link 4131 and a second link 4133 connected by an elastic member 4132, an end of the first link 4131 is fixedly connected to the pressing member 411, and an end of the second link 4133 is fixedly connected to the fixing member 412. When no marking is required, the elastic member 4132 is in a compressed state to support the first link 4131; when the loading position is required to be marked, the pressing piece 411 is pressed, the elastic piece 4132 is further contracted, and the pressing piece 411 rotates relative to the fixing piece 412, so that the elastic buckle is clamped on the fixing piece 412, and the structure is simple. In this embodiment, the elastic member 4132 is a spring.

Optionally, a cylinder is sleeved outside the elastic member 4132, and the cylinder is slidably connected to both the first connecting rod 4131 and the second connecting rod 4133, so as to ensure that the first connecting rod 4131, the elastic member 4132 and the second connecting rod 4133 are positioned in the same straight line when the first connecting rod 4131 applies pressure to the elastic member 4132. For example, the outer circumferential surfaces of the first connecting rod 4131 and the second connecting rod 4133 are provided with protruding blocks, the cylinder body is provided with sliding grooves, and the protruding blocks and the sliding grooves are matched to realize sliding connection.

It is to be understood that the above examples of the present utility model are provided for clarity of illustration only and are not limiting of the embodiments of the present utility model. Various obvious changes, rearrangements and substitutions can be made by those skilled in the art without departing from the scope of the utility model. It is not necessary here nor is it exhaustive of all embodiments. Any modification, equivalent replacement, improvement, etc. which come within the spirit and principles of the utility model are desired to be protected by the following claims.

Claims

1. A 384 microwell plate loading aid, comprising:

the box body (1) is of a cuboid structure, the box body (1) is provided with a containing bin (11), and the containing bin (11) is used for containing the 384 micro-pore plates (2);

the indication strip (3) is selectively arranged on the upper surface of the box body (1), and the indication strip (3) is used for marking the 384 micro-plates (2) in a partitioning way;

the marking keys (4) are arranged in one-to-one correspondence with the micropores of the 384-micropore plate (2), the marking keys (4) comprise first marking keys (41) and second marking keys (42), the first marking keys (41) are arranged on the outer peripheral surface of the box body (1) in the length direction, the second marking keys (42) are arranged on the outer peripheral surface of the box body (1) in the width direction, and the marking keys (4) can be pressed to mark the micropores.

2. The 384-well plate loading aid according to claim 1, wherein the size of the receiving compartment (11) is matched to the size of the 384-well plate (2).

3. The 384-microwell plate loading auxiliary device as claimed in claim 1, wherein the indicator strip (3) comprises a first indicator strip (31) and a second indicator strip (32), the first indicator strip (31) is disposed along a length direction of the cartridge body (1), and the second indicator strip (32) is disposed along a width direction of the cartridge body (1).

4. The 384-microwell plate sample loading auxiliary device according to claim 3, wherein the box body (1) is provided with a clamping groove (12), the clamping groove (12) is surrounded on the periphery of the accommodating bin (11) and extends along the depth direction of the accommodating bin (11), both ends of the indicator strip (3) are provided with bending parts, and the bending parts can be inserted into the clamping groove (12).

5. The 384-microwell plate loading aid as claimed in claim 1, wherein the first marking key (41) is provided with a number identifier of numbers 1 to 24, and the second marking key (42) is provided with a letter identifier of letters a to P.

6. The 384-microwell plate loading aid as claimed in claim 1, wherein the first marking key (41) and/or the second marking key (42) comprises a pressing piece (411) and a fixing piece (412) which are rotatably connected, the fixing piece (412) is connected with the box body (1), the pressing piece (411) is provided with an elastic buckle, the first marking key (41) and/or the second marking key (42) is configured to press the pressing piece (411), and the pressing piece (411) can rotate relative to the fixing piece (412) and enable the elastic buckle of the pressing piece (411) to be clamped with the fixing piece (412).

7. The 384-microwell plate loading auxiliary device as claimed in claim 6, wherein said pressing member (411) is provided with a side plate (4111), and said elastic buckle is provided on an inner side surface of said side plate (4111).

8. The 384-microwell plate loading aid as claimed in claim 6, wherein a supporting frame is connected between the pressing member (411) and the fixing member (412).

9. The 384-microwell plate loading aid as claimed in claim 8, wherein the support frame comprises a first link (4131) and a second link (4133) connected by an elastic member (4132), an end of the first link (4131) is fixedly connected with the pressing member (411), and an end of the second link (4133) is fixedly connected with the fixing member (412).

10. The 384-microwell plate loading aid as claimed in claim 9, wherein the elastic member (4132) is a spring.