CN219016044U - Slide loading device and scanning system - Google Patents

Abstract

The utility model provides a slide loading device and a scanning system, and relates to the technical field of auxiliary equipment for clinical diagnosis. The device comprises a frame, an objective table module and a transfer module, wherein the objective table module and the transfer module are arranged on the frame; the objective table module comprises a slide frame for loading slides; the transfer module comprises a turntable mechanism which is in driving connection with the slide frame; the frame is provided with a loading area for taking and placing the slide on the slide frame and a scanning area for scanning the slide; the slide rack is driven by the turntable mechanism to move along a path which at least passes through the loading area and the scanning area. The utility model provides a slide loading device, which drives a slide rack to rotate on a path passing through at least a loading area and a scanning area through a turntable mechanism, so that the slide is conveniently loaded and taken in the loading area.

Description

Slide loading device and scanning system

Technical Field

The utility model relates to the technical field of auxiliary equipment for clinical diagnosis, in particular to a slide loading device and a scanning system.

Background

Slide scanning detection is widely applied to pathology, hematology, cytology and other diagnosis, is widely applied to clinical diagnosis, and is an indispensable work in medical research. After the biological material is flaked and dyed, a worker performs scanning detection on a scanning microscope.

There are currently on the market single slide scanners and high throughput scanners. The high-throughput scanner has large scanning amount, usually adopts a mode of matching a slide bin, clamping jaws and an objective table, has large volume, complex structure and low price, and is generally suitable for large hospitals.

Small hospitals such as villages and towns have low scanning amount and limited budget, so that a slide scanner with low price, high scanning speed and proper scanning amount is needed. The slide platform of a single slide scanner typically holds a single slide. The slides made of the cell samples are generally stored in a slide box, and when detection is needed, the slides are taken out from the slide box, and the slides are placed in a slide frame in a slide scanner. Because the light inside the instrument is darker, the time for placing the slide is longer and the efficiency is lower.

Disclosure of Invention

Aiming at the technical problems, the utility model provides the slide loading device and the scanning system, which can put slides into the slide frame in the non-shielding loading area, improve the speed and the quantity for placing the slides, greatly improve the slide scanning efficiency, and have simple structure and lower cost. The technical scheme is as follows:

a slide loading device comprises a frame, an objective table module and a transfer module, wherein the objective table module and the transfer module are arranged on the frame; the objective table module comprises a slide frame, wherein the slide frame is used for loading the slide; the transfer module comprises a turntable mechanism which is in driving connection with the slide frame; the frame is provided with a loading area for taking and placing the slide on the slide frame and a scanning area for scanning the slide; the slide rack is driven by the turntable mechanism to move along a path which at least passes through the loading area and the scanning area.

Further, the turntable mechanism includes a disk and a drive member, and the slide holder is fixed to the disk.

Further, the slide loading device further comprises a translation table module which is in driving connection with the whole turntable mechanism, and the movement path of the turntable mechanism driven by the translation table module at least passes through the loading area and the scanning area.

Further, the translation stage module includes a first direction translation mechanism; the first direction translation mechanism includes: the first bottom plate, the first motor, a first lead screw in transmission connection with the first motor and a first sliding table in threaded connection with the first lead screw; one end of the first sliding table is fixedly connected with the whole turntable mechanism, and the other end of the first sliding table is slidably connected with the first bottom plate.

Further, the translation stage module further comprises a second direction translation mechanism; the second direction translation mechanism includes: the second motor, a second lead screw in transmission connection with the second motor and a second sliding table in threaded connection with the second lead screw; the second slipway is fixedly connected with the first bottom plate.

Still further, the slide rack includes a slide rack body and a fixing member fixed to the slide rack body; the fixing member is formed with a slide carrying position for fixing a slide.

Further, the fixing piece comprises a pressing piece, a slide block and an elastic piece; the pressing piece and the slide block are fixed at opposite positions on the slide frame body, and the slide bearing position is formed between the pressing piece and the slide block; the two ends of the elastic piece are respectively connected with the pressing piece and the slide frame body, and the elastic piece has acting force for driving the pressing piece to move towards the slide stop block.

Further, a connecting piece is arranged on the turntable mechanism and/or the slide frame, and the turntable mechanism and the slide frame are detachably connected through the connecting piece.

Further, the connector includes: a pair of magnets respectively fixed on the turntable mechanism and the slide frame.

Still further, the connector further comprises: a pair of buckles respectively fixed on the turntable mechanism and the slide frame.

Further, a slide scanning system includes a scanning device, and a slide loading device according to any one of the above aspects.

The utility model has the beneficial effects that:

1. the slide loading device is provided with the turntable mechanism, and when the slide scanning of the scanning area is finished, the driving device drives the turntable mechanism to rotate, and the turntable mechanism rotates to the loading area to install and replace the slide. The loading area is not shielded by the instrument, and the light is sufficient. The device utilizes a simple structure, avoids the shielding of light rays when the slide is replaced, improves the speed of loading and unloading the slide, realizes high automation and continuous uninterrupted slide scanning, and greatly improves the working efficiency of the slide scanner.

2. The slide loading device is further provided with the translation table module, and before placing a slide, the stage module is moved to a place without shielding by the translation table module, and the slide is placed at a position with sufficient light, so that the time for placing the slide is saved, and the efficiency is improved. Meanwhile, the slide frame is moved in the first direction and the second direction by the translation stage module, so that different objective lenses can be switched, and the position of a slide can be further adjusted.

3. The traditional single-chip scanner can only place one slide at a time, and after scanning is finished, the slide needs to be detached and replaced by another slide, so that the slide scanning efficiency is low. The slide loading device can set the number of the slide racks and the slide bearing positions according to actual needs, so that a plurality of slides can be loaded at one time, the frequency of replacing the slides is reduced, and the slide scanning efficiency is improved.

4. The slide loading device is a further improvement on the objective table in the existing single-plate slide scanner, integrates the objective table and the slide bin, has small volume, simple structure and low manufacturing cost compared with a high-flux scanner, is suitable for small hospitals in the amount of scanning, and saves resources.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present utility model, the drawings that are required to be used in the description of the embodiments of the present utility model will be briefly described below.

FIG. 1 is a schematic overall construction of an embodiment;

FIG. 2 is a top view of FIG. 1;

FIG. 3 is a side view of FIG. 1;

FIG. 4 is a top view of a transfer table mechanism and translation table module in one embodiment;

fig. 5 is a schematic diagram of one embodiment installed in a slide scanning system.

The same reference numbers will be used throughout the drawings to refer to identical or similar parts or components.

1. A stage module; 11. a slide holder; 111. a pressing member; 112. a slide block; 113. an elliptical hole;

2. a turntable mechanism; 21. a disc; 22. a magnet; 23. a female buckle;

3. a translation stage module; 31. and a second direction translation mechanism.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the present utility model more apparent, the embodiments of the present utility model will be described in further detail with reference to the accompanying drawings. Examples of the embodiments are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements throughout, or elements having like or similar functionality. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the utility model.

The slide loading device, as shown in fig. 1, comprises a frame, a stage module 1 and a transfer module, wherein the stage module 1 and the transfer module are mounted on the frame. The stage module 1 includes a slide holder 11 for loading slides, and the transfer module includes a turntable mechanism 2 drivingly connected to the slide holder 11. The frame is provided with a loading area for taking and placing the slide on the slide frame 11 and a scanning area for scanning the slide, and a moving path of the slide frame 11 driven by the turntable mechanism 2 at least passes through the loading area and the scanning area. When the slide rack is used, the slide rack 11 on which the slide is required to be mounted or replaced is rotated from the scanning area to the loading area by using the turntable mechanism 2, so that the slide is mounted and replaced; and then the scanning device is rotated to a scanning area for observation and scanning.

In practical application, as shown in fig. 5, the slide loading device is fixed at one side of the scanner, and when the slide is scanned, the slide to be scanned is moved into the scanner by the slide loading device; when loading slides, the slide to be scanned is moved outside the scanner by the slide loading device. At this time, the scanning area is an internal area of the scanner, and light is darker due to shielding of the objective lens and the like; the loading area is an area outside the scanner without shielding by an instrument, and the area has brighter light, so that the glass slide can be conveniently loaded.

In one embodiment, as shown in fig. 4, the turntable mechanism 2 includes a disk 21, a worm wheel, a worm, a coupling, and a driving member, which is a motor. The disc 21 is fixed on the upper surface of the worm wheel and is coaxial with the worm wheel, an output shaft of the motor is connected with the worm through a coupler, and the worm is matched with the worm wheel. The centers of regular hexagons enclosed by one ends of the six slide holders 11 coincide with the centers of circles of the disks 21. The motor drives the worm to drive the worm wheel to rotate through the coupler, and then drives the slide rack 11 to rotate clockwise through the disc 21, so that the slide rack 11 in the scanning area is rotated to the loading area, and then the slide is installed or replaced; alternatively, the slide holder 11 of the loading area may be rotated to the scanning area and then the slides carried thereon scanned.

In one embodiment, as shown in fig. 1 and 3, the slide loading device further includes a translation stage module 3 drivingly connected to the entire turntable mechanism 2, and the movement path of the turntable mechanism 2 driven by the translation stage module 3 passes through at least the loading area and the scanning area.

In one embodiment, the translation stage module 3 includes a first direction translation mechanism. The first direction translation mechanism comprises a first bottom plate, a first motor, a first lead screw in transmission connection with the first motor and a first sliding table in threaded connection with the first lead screw. One end of the first sliding table is fixedly connected with the whole turntable mechanism 2, and the other end of the first sliding table is slidably connected with the first bottom plate.

The first motor works, the first sliding table is driven to translate on the first bottom plate through the first lead screw, the whole turntable mechanism 2 and the objective table module 1 are driven to translate along the first direction, and then the slide frame 11 is driven to translate on a path passing through the scanning area and the loading area, so that the slide is conveniently loaded and taken and scanned.

In one embodiment, the translation stage module 3 further comprises a second direction translation mechanism 31; the second direction translation mechanism 31 comprises a second motor, a second lead screw in transmission connection with the second motor and a second sliding table in threaded connection with the second lead screw; the second sliding table is fixedly connected with the first bottom plate; the moving path of the first direction translation mechanism driven by the second sliding table at least passes through the loading area and the scanning area.

The second motor works, the second sliding table is driven to translate through the second lead screw, and the second sliding table drives the first bottom plate to translate, so that the first direction translation mechanism, the turntable mechanism 2 and the objective table module 1 are driven to translate, and the translation path passes through the scanning area and the loading area. On one hand, the glass slide is convenient to be assembled, taken and scanned; on the other hand, by means of the first and second direction translation mechanisms 31, the position of the slide in the scanning area can be further adjusted, for example by switching the objective lens of different magnification, adjusting the specific position under the objective lens.

In one embodiment, as shown in FIG. 2, the slide holder 11 includes a slide holder body and a fixing member fixed to the slide holder body, the fixing member having a slide carrying position formed thereon for fixing a slide. The fixing member includes a pressing member 111, a slide stopper 112, and an elastic member. The hold-down member 111 is located at one end of the upper surface of the slide holder body near the center of the disk 21, and the slide stopper 112 is fixed at one end of the upper surface of the slide holder body opposite to the hold-down member 111, with the slide bearing position formed between the hold-down member 111 and the slide stopper 112. The two ends of the elastic piece are respectively connected with the pressing piece 111 and the slide frame body, and the elastic piece has acting force for driving the pressing piece 111 to move towards the slide stop 112 on the pressing piece 111. When the slide rack is used, one end of a slide abuts against the pressing piece 111, the elastic piece is compressed by applying pressure, the slide is placed on the slide rack body, the pressure is released, the elastic piece presses the pressing piece 111, the other end of the slide is pressed on the end of the slide stop 112, and therefore the slide is fixed on the slide rack 11.

The elastic member can be a spring or the like, and can be arranged in different amounts according to actual requirements. In other embodiments, the pressing member 111 and the slide stopper 112 may be fixed at any relative position on the slide frame body according to practical situations, for example, the pressing member 111 is located at a position of the lower surface of the slide frame body away from the center of the disk 21, or the pressing member 111 is located at a side of the slide frame body, etc. In other embodiments, the securing member may be other components, such as a clamping jaw or the like.

In other embodiments, two or more slide bearing positions can be reserved on the slide frame body by one slide frame 11 according to actual needs, and meanwhile, a corresponding number of fixing pieces are arranged, so that two or more slides can be mounted on one slide frame 11, and the efficiency of loading and scanning slides is further improved.

In one embodiment, as shown in FIG. 2, the slide holder 11 has an elliptical hole 113 at an end remote from the center of the disk 21 to facilitate access to the slide holder 11. In other embodiments, other components may be provided at any location on the slide rack 11 according to actual needs to facilitate the handling of the slide rack 11, such as bumps and the like.

In one embodiment, as shown in fig. 2, the stage module 1 includes six slide holders 11, and one end of the six slide holders 11 near the center of the disk 21 encloses a regular hexagon. In other embodiments, the number of slide holders 11 may be any number, and the slide holders 11 may be mounted around the center of the disk 21.

In one embodiment, the slide frame 11 is provided with a male buckle at one end near the center of the circle of the disc 21; the upper surface of the disc 21 is fixed with a female buckle 23 matched with the male buckle, and the slide frame 11 is buckled and connected with the disc 21. The back of the slide frame 11 is provided with an iron sheet, and the upper surface of the disc 21 is fixed with a magnet 22 which is matched with the shape and the position of the iron sheet, so that the slide frame 11 is magnetically connected with the disc 21. The slide holder 11 is stably attached to the disk 21 by a pair of snaps and a pair of magnets 22.

In other embodiments, the slide holder 11 may also be removably coupled to the disk 21 by other connectors that may be secured to the turntable mechanism 2 and/or the slide holder 11. The connector may be a pair of connectors, a set of collars, a set of snaps, a jaw, or the like. One or more connectors can be selected for use according to actual needs, so that the slide frame 11 and the turntable mechanism 2 can be connected more stably, and the dislocation problem is reduced.

A slide scanning system, as shown in fig. 5, includes a scanning device including a macro-positioning module and a micro-focusing module, and a slide loading device according to any of the above embodiments. The macro positioning module comprises a first objective lens with relatively low magnification, wherein the first objective lens is used for positioning the position of a sample to be detected in a glass slide; the micro-focus module includes a second objective lens with a relatively high magnification for scanning the positioned sample location to enable the slide scanning system to acquire a scanned image.

In use, the slide holder 11 with slides is mounted on the disk 21 and the slide holder 11 is moved to the scan area by the translation stage module 3. Then, the objective lens can be switched by the second direction translation mechanism 31 and the first direction translation mechanism, and the position of the slide under the objective lens is further adjusted, so that the scanning is more accurate. The scanned slide is rotated to a loading area through a turntable mechanism 2, and the slide is replaced in the loading area so as to carry out the next scanning; while the unscanned slides of the loading area can be moved to the scanning area for scanning. The entire turntable mechanism 2 and stage module 1 may also be moved to the loading area by the translation stage module 3 for loading and unloading slides.

In the description of the present specification, the terms "embodiment," "present embodiment," "in one embodiment," and the like, if used, mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present utility model. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples; furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

In the description of the present specification, the terms "connected," "mounted," "secured," "disposed," "having," and the like are to be construed broadly, e.g., as being either fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the terms in this application will be understood by those of ordinary skill in the art as the case may be.

In the description of this specification, relational terms such as "first" and "second", and the like, are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.

The embodiments have been described so as to facilitate a person of ordinary skill in the art in order to understand and apply the present technology, it will be apparent to those skilled in the art that various modifications may be made to these examples and that the general principles described herein may be applied to other embodiments without undue burden. Therefore, the present application is not limited to the above embodiments, and modifications to the following cases should be within the scope of protection of the present application: (1) the technical scheme of the utility model is taken as the basis and combined with the new technical scheme implemented by the prior common general knowledge, and the technical effect produced by the new technical scheme is not beyond that of the utility model; (2) equivalent replacement of part of the characteristics of the technical scheme of the utility model by adopting the known technology produces the technical effect the same as that of the utility model; (3) the technical scheme of the utility model is taken as a basis for expanding, and the essence of the expanded technical scheme is not beyond the technical scheme of the utility model; (4) equivalent transformation made by the content of the specification and the drawings of the utility model is directly or indirectly applied to other related technical fields.

Claims (11)

1. A slide loading device comprises a frame, and is characterized in that,

the device also comprises an objective table module and a transfer module which are arranged on the frame;

the stage module includes a slide rack for loading the slide;

the transfer module comprises a turntable mechanism which is in driving connection with the slide frame;

the frame is provided with a loading area for taking and placing the slide on the slide frame and a scanning area for scanning the slide;

the moving path of the slide rack driven by the turntable mechanism at least passes through the loading area and the scanning area.

2. The slide loading device of claim 1, wherein,

the turntable mechanism comprises a disc and a driving piece, and the slide rack is fixed on the disc.

3. The slide loading device of claim 1, wherein,

the slide loading device further comprises a translation table module which is in driving connection with the whole turntable mechanism, and the movement path of the turntable mechanism driven by the translation table module at least passes through the loading area and the scanning area.

4. A slide loading device as recited in claim 3, wherein,

the translation stage module comprises a first direction translation mechanism;

the first direction translation mechanism includes: the device comprises a first bottom plate, a first motor, a first lead screw in transmission connection with the first motor and a first sliding table in threaded connection with the first lead screw;

one end of the first sliding table is fixedly connected with the whole turntable mechanism, and the other end of the first sliding table is slidably connected with the first bottom plate.

5. The slide loading device of claim 4 wherein,

the translation stage module further comprises a second direction translation mechanism;

the second direction translation mechanism includes: the second motor, a second lead screw in transmission connection with the second motor and a second sliding table in threaded connection with the second lead screw;

the second sliding table is fixedly connected with the first bottom plate.

6. The slide loading device according to any one of claims 1 to 5, wherein,

the slide frame comprises a slide frame body and a fixing piece fixed on the slide frame body;

the fixing piece is provided with a slide bearing position for fixing the slide.

7. The slide loading device of claim 6 wherein,

the fixing piece comprises a pressing piece, a slide stop block and an elastic piece;

the pressing piece and the slide block are fixed at opposite positions on the slide frame body, and the slide bearing position is formed between the pressing piece and the slide block;

the two ends of the elastic piece are respectively connected with the pressing piece and the slide frame body, and the elastic piece has acting force for driving the pressing piece to move towards the slide stop block.

8. The slide loading device according to any one of claims 1 to 5, wherein,

the turntable mechanism and/or the slide frame are/is provided with a connecting piece, and the turntable mechanism and the slide frame are detachably connected through the connecting piece.

9. The slide loading device of claim 8, wherein,

the connector includes: a pair of magnets respectively fixed on the turntable mechanism and the slide frame.

10. The slide loading device of claim 9 wherein,

the connector further comprises: a pair of buckles respectively fixed on the turntable mechanism and the slide frame.

11. A slide scanning system comprising a scanning device, further comprising a slide loading device as claimed in any one of claims 1 to 5.

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