CN218961401U - Device for preparing platelet-rich fibrin membrane - Google Patents

Abstract

The utility model belongs to the technical field of platelet protein membrane preparation, and particularly relates to a device for preparing a platelet-rich fibrin membrane. The centrifugal tube comprises a centrifugal tube body, wherein the upper end and the lower end of the centrifugal tube body are provided with internal threads in opposite directions, a tube cover matched with the internal threads is arranged on the centrifugal tube body, a through round hole is formed in the center of the tube cover, and a plug is arranged in the round hole. The utility model is provided with the extrusion sheet, and the extrusion sheet is close by rotating the pipe cover, so that the PRF gel can be directly pressed into a film, the pollution problem caused by the fact that the PRF gel is taken out and then pressed into the film is avoided, the small through holes and the rubber protective film are arranged, meanwhile, liquid rich in various growth factors and anti-inflammatory factors is collected and extruded from the PRF gel, and the utilization of the growth factors and the anti-inflammatory factor liquid is realized.

Description

Device for preparing platelet-rich fibrin membrane

Technical Field

The utility model belongs to the technical field of platelet protein membrane preparation, and particularly relates to a device for preparing a platelet-rich fibrin membrane.

Background

Platelet-rich-fibrin (PRF), a biological material derived entirely from peripheral blood, is prepared in a similar manner to the first generation Platelet aggregation growth factor PRP, however PRF does not require the addition of exogenous substances during its preparation, which also avoids cross-infection and immune reactions that may occur during its preparation.

The PRF contains transforming growth factors (TGF beta-1), platelet-derived growth factors (PDGF), vascular Endothelial Growth Factors (VEGF) and the like, has fibrin scaffolds and slow release functions, has good capability of promoting soft tissue regeneration, and the tissue repair effect of the PRF is mainly realized through two aspects, namely the regulation function of cytokines and the cell scaffolds of fibrin. PRF will degrade slowly over time, and thus various growth factors within will gradually release over time into surrounding tissue, continuously stimulating regeneration of soft and hard tissue surrounding the implant. In addition, the PRF contains a large amount of cytokines derived from platelets, which activate leukocytes in the operative region of the patient and promote the anti-inflammatory and anti-infective effects of the operative region. PRF has been widely used in recent years in cases where there is a severe soft and hard tissue defect at the site of implantation due to its excellent ability to promote soft and hard tissue regeneration.

However, the current preparation of platelet rich fibrin membranes has the following problems:

after centrifugation is complete, the PRF gel is removed from the centrifuge tube, and then placed on gauze, which is pressed to dehydrate the PRF gel to produce the PRF membrane. However, the PRF gel is directly exposed to laboratory environment, so that the pollution problem exists, the preparation quality is further affected, and the liquid squeezed out of the PRF gel is directly poured out, so that the liquid rich in various growth factors and anti-inflammatory factors is wasted.

Disclosure of Invention

The utility model aims to provide a device for preparing a platelet-rich fibrin membrane, which is provided with a squeezing sheet, can directly press PRF gel into a membrane, is provided with a small through hole and a rubber protection film, and is convenient for collecting liquid which is squeezed out of the PRF gel and is rich in various growth factors and anti-inflammatory factors.

In order to achieve the technical effects, the technical scheme adopted by the utility model is as follows:

the device for preparing the platelet-rich fibrin membrane comprises a centrifuge tube body, wherein an inner thread is arranged on the inner wall of the centrifuge tube body, a tube cover matched with the inner thread is arranged on the inner wall of the centrifuge tube body, a through round hole is formed in the center of the tube cover, and a plug is arranged in the round hole.

Preferably, the pipe cover is connected with an extrusion sheet through a rotating structure, a through hole is formed in the center of the extrusion sheet, a rubber protection film is arranged on the through hole, a circular groove is further formed in the center of the joint surface of the extrusion sheet and the pipe cover, a plurality of strip-shaped concave liquid discharge grooves are formed in the extrusion sheet along the radial direction by taking the groove as a starting point, and a plurality of micropores are formed in the liquid discharge grooves.

Preferably, the rotating structure comprises a circular rotating body and a rotating groove, the rotating body is arranged on one side face of the pipe cover, the cross-section structure of the rotating body is I-shaped, and the rotating groove is arranged on the extrusion sheet and is in rotating fit with the rotating body.

Preferably, the diameter of the extrusion sheet is smaller than the diameter of the tube cap.

Compared with the prior art, the utility model has the beneficial effects that:

1. the device is provided with the extrusion sheet, and the extrusion sheet is close to the device through the rotation of the pipe cover, so that the PRF layer can be directly pressed into a film, and the pollution problem caused by taking out the PRF gel and then pressing the PRF gel into the film is avoided;

2. the utility model is provided with the small through holes and the rubber protective film, so that liquid rich in various growth factors and anti-inflammatory factors can be conveniently collected through the injector.

Drawings

The accompanying drawings are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the embodiments of the utility model, serve to explain the utility model.

In the drawings:

figure 1 is a schematic diagram of the main structure of the present utility model,

figure 2 is a bottom view of the tube cap of the present utility model,

figure 3 is a cross-sectional view of the rotating structure of the present utility model,

FIG. 4 is a schematic view of the structure of the extruded sheet of the present utility model.

The centrifugal tube comprises a centrifugal tube body 1, micropores 3, internal threads 4, extrusion sheets 5, internal hexagonal holes 6, grooves 7, through holes 8, a tube cover 9, round holes 10, a horizontal groove 11, a plug 12, a rotator 13, micropores and a liquid discharge groove 14.

Detailed Description

The preferred embodiments of the present utility model will be described below with reference to the accompanying drawings, it being understood that the preferred embodiments described herein are for illustration and explanation of the present utility model only, and are not intended to limit the present utility model.

Examples:

referring to fig. 1-4, a device for preparing platelet-rich fibrin membrane, including centrifuging tube body 1, centrifuging tube body 1 has l5ml, 50ml, can insert in the current centrifuge, the internal thread 3 has been seted up to centrifuging tube body 1's inner wall, and centrifuging tube body 1's both ends are provided with internal thread 3 complex tube cap 8, the round hole 9 that link up has been seted up at tube cap 8's center, is provided with stopper 11 in the round hole 9, for threaded connection's mode, centrifuging tube body 1, tube cap 8 and stopper 11's material are the medical plastics material of stereoplasm.

Furthermore, the tube cover 8 is further provided with a "one" shaped slot 10, the "one" shaped slot 10 is communicated with the round hole 9, but the "one" shaped slot 10 does not penetrate the other end face of the tube cover 8, so that the tube cover 8 can be more conveniently clamped into the "one" shaped slot 10 to realize rotation when the tube cover 8 is rotated.

Further, an inner hexagonal hole 5 is formed in the upper end face of the plug 11, and the plug 11 is inserted into an inner hexagonal screwdriver to rotate.

The pipe cover 8 is connected with the extrusion piece 4 through a rotating structure, the rotating structure comprises a circular rotating body 12 and a rotating groove 13, the rotating body 12 is integrally formed on the side surface of the pipe cover 8, which is not provided with the I-shaped groove 10, the cross section structure of the rotating body 12 is I-shaped, and the rotating groove 13 is provided on the extrusion piece 4 and is in rotating fit with the rotating body 12.

When the centrifuge tube is used, the tube cover 8 moves towards the middle of the centrifuge tube body 1 through the tube cover 8, so that the extrusion sheet 4 is pushed to move towards the middle of the centrifuge tube body 1, but the extrusion sheet 4 cannot rotate, and damage to the PRF layer is avoided.

The through hole 7 is formed in the center of the extrusion piece 4, a rubber protection film is arranged on the through hole 7, liquid can be extracted after the injection needle is punctured, and then sealing can be achieved after the needle is pulled out under the flexible characteristic of the rubber protection film.

The center of the joint surface of the extrusion piece 4 and the pipe cover 8 is also provided with a circular groove 6, a plurality of strip-shaped and concave drainage grooves 14 are formed in the extrusion piece 4 along the radial direction by taking the groove 6 as a starting point, a plurality of through micropores 2 are formed in the drainage grooves 14, and the aperture of the micropores 2 is 0.4x0.4mm. The other side of the extrusion piece 4 is a plane.

When the PRF film is prepared by extrusion, the extruded liquid enters the liquid discharge groove 14 through the micropore 2, then flows into the groove 6 through the liquid discharge groove 14, the groove 6 is communicated with the round hole 9, and the liquid in the groove 6 can be pumped out by using an injection needle.

The diameter of the extrusion sheet 4 is smaller than the diameter of the tube cover 8 by 0.5mm.

The principle and the use flow of the utility model are as follows:

in use, the cap 8 and plug 11 are screwed, blood is injected into the centrifuge tube 1 by a syringe, and the centrifuge tube 1 is placed in a centrifuge. The centrifugation operation is started.

After centrifugation, the red blood cell layer is positioned at the lower part of the centrifuge tube body 1, a hexagonal screwdriver is used for unscrewing a plug 11 at the lower part of the centrifuge tube body 1, a clean injector is inserted into a through hole 7 on the extrusion sheet 4, and the red blood cell layer is extracted through a rubber protection film.

The stopper 8 on the upper part of the centrifuge tube is then unscrewed, and a clean syringe is inserted into the through hole 7 in the squeeze sheet 4 as well, and the yellow liquid on the upper part is drawn through the rubber protection film, and is not used and discarded.

Finally, the straight line is clamped into a straight line groove 10 of the pipe cover 8 to realize rotation, so that the two extrusion sheets 4 are mutually close to each other, PRF gel is extruded, PRF gel is dehydrated to finally form a platelet-rich fibrin film, and liquid rich in growth factors is obtained through extrusion dehydration and is extracted for standby.

The foregoing has shown and described the basic principles, principal features and advantages of the utility model. It will be understood by those skilled in the art that the present utility model is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present utility model, and various changes and modifications may be made without departing from the spirit and scope of the utility model, which is defined in the appended claims. The scope of the utility model is defined by the appended claims and equivalents thereof.

Claims (4)

1. An apparatus for preparing a platelet rich fibrin membrane, characterized by: including centrifuging tube body (1), internal thread (3) have been seted up to centrifuging tube body (1) inner wall, and be provided with internal thread (3) complex tube cap (8), round hole (9) that link up have been seted up at the center of tube cap (8), are provided with stopper (11) in round hole (9).

2. An apparatus for preparing a platelet rich fibrin membrane according to claim 1, wherein: the pipe cover (8) is connected with the extrusion piece (4) through the rotating structure, through-hole (7) have been seted up at the center of extrusion piece (4), be provided with the rubber protection film on through-hole (7), the center of extrusion piece (4) and pipe cover (8) interface still is provided with circular shape recess (6), use recess (6) as the starting point on extrusion piece (4), offered a plurality of rectangular shape and concave drain groove (14) along the radius direction, be provided with a plurality of micropore (2) in drain groove (14).

3. An apparatus for preparing a platelet rich fibrin membrane according to claim 2, wherein: the rotary structure comprises a circular rotary body (12) and a rotary groove (13), wherein the rotary body (12) is arranged on one side surface of the pipe cover (8), the cross section structure of the rotary body (12) is I-shaped, and the rotary groove (13) is arranged on the extrusion sheet (4) and is in rotary fit with the rotary body (12).

4. An apparatus for preparing a platelet rich fibrin membrane according to claim 3, wherein: the diameter of the extrusion piece (4) is smaller than that of the pipe cover (8).

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