CN218917279U - Micro-fluidic chip detection platform - Google Patents

Micro-fluidic chip detection platform Download PDF

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Publication number
CN218917279U
CN218917279U CN202223048682.2U CN202223048682U CN218917279U CN 218917279 U CN218917279 U CN 218917279U CN 202223048682 U CN202223048682 U CN 202223048682U CN 218917279 U CN218917279 U CN 218917279U
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magnetic field
field generator
platform
microfluidic chip
placement platform
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庞作波
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Hohhot Junyuan Precision Testing Technology Co ltd
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Hohhot Junyuan Precision Testing Technology Co ltd
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Abstract

The utility model discloses a microfluidic chip detection platform which comprises a placement platform, a first magnetic field generator and a first lifting mechanism, wherein the first magnetic field generator can generate a first magnetic field, and the placement platform is positioned in the first magnetic field; the first lifting mechanism is provided with a first driving piece, the installation end of the first driving piece is connected with the placement platform, and the driving end of the first driving piece is connected with the first magnetic field generator; the first driving piece can drive the first magnetic field generator to be far away from or close to the placing platform so as to adjust the first magnetic field distribution. Through placing a plurality of micro-fluidic chips on the placing platform, the first driving piece enables the first magnetic field generator to lift, so that the first magnetic field changes, and then the detection is completed simultaneously by the plurality of micro-fluidic chips, and the working efficiency of the micro-fluidic chip detection platform is improved.

Description

Micro-fluidic chip detection platform
Technical Field
The utility model relates to the technical field of microfluidic chips, in particular to a microfluidic chip detection platform.
Background
Microfluidic chip technology (Microfluidics) integrates basic operation units of sample preparation, reaction, separation, detection and the like in biological, chemical and medical analysis processes onto a micron-scale chip, and the chip automatically completes the whole analysis process. Basic operation units such as sample preparation, biological and chemical reactions, separation, detection and the like can be integrated in the microfluidic chip system, a network is formed by micro channels, and controllable fluid penetrates through the whole system, so that various functions of conventional tests are realized.
The existing microfluidic chip detection platform comprises a magnet unit, a fixed support, a driving motor and a microfluidic chip, wherein the magnet unit is connected with the driving motor through the fixed support, the driving motor drives the magnet unit to do one-dimensional reciprocating motion in the horizontal direction, the microfluidic chip is fixed in a magnetic field generated by the magnet unit through a clamp, and the magnet unit moves to generate a changed magnetic field, so that the microfluidic chip is detected.
In the existing detection process of the microfluidic chip, when a plurality of microfluidic chips are required to be detected, the microfluidic chips are required to be sequentially placed in a magnetic field through a clamp, so that the detection of the microfluidic chips is sequentially completed; the clamp is required to be sequentially operated, so that the detection efficiency of the microfluidic chip is reduced.
Disclosure of Invention
Therefore, the technical problem to be solved by the utility model is that in the prior art, when a plurality of microfluidic chips are required to be detected, the microfluidic chips are required to be sequentially fixed in a magnetic field through a clamp, so that the microfluidic chips are enabled to complete detection; the clamp is required to be sequentially operated, so that the detection efficiency of the microfluidic chip is reduced.
For this purpose, the utility model provides a microfluidic chip detection platform, which is characterized by comprising:
the placement platform is suitable for placing a plurality of microfluidic chips;
a first magnetic field generator capable of generating a first magnetic field, the placement platform being located within the first magnetic field;
the first lifting mechanism is provided with a first driving piece, the installation end of the first driving piece is fixedly connected with the placing platform, and the driving end of the first driving piece is connected with the first magnetic field generator;
the first driving piece can drive the first magnetic field generator to be far away from or close to the placing platform so as to adjust the first magnetic field change.
Optionally, the microfluidic chip detection platform described above, the first lifting mechanism includes:
the first screw rod is fixedly connected with the driving end of the first driving piece, and the other end of the first screw rod is in threaded connection with the first magnetic field generator.
Optionally, the microfluidic chip detection platform further comprises at least one first guide rod, one end of the first guide rod is fixedly connected with the placement platform, and the other end of the first guide rod is slidably connected with the first magnetic field generator.
Optionally, the microfluidic chip detection platform further includes:
a second magnetic field generator capable of generating a second magnetic field, and the placement platform is located within the second magnetic field;
the second lifting mechanism is provided with a second driving piece, the installation end of the second driving piece is fixedly connected with the placing platform, and the driving end of the second driving piece is connected with the second magnetic field generator;
the second driving piece can drive the second magnetic field generator to be far away from or close to the placing platform so as to adjust the second magnetic field distribution.
Optionally, the microfluidic chip detection platform, the second lifting mechanism includes:
the second screw rod is fixedly connected with the driving end of the second driving piece at one end, and the second magnetic field generator is connected with the other end of the first screw rod in a threaded mode.
Optionally, the micro-fluidic chip detection platform further comprises at least one second guide rod, one end of the second guide rod is fixedly connected with the placement platform, and the other end of the second guide rod is slidably connected with the second magnetic field generator.
Optionally, in the above micro-fluidic chip detection platform, the placement platform is provided with a plurality of through holes, and the through holes are suitable for plugging the micro-fluidic chip.
Optionally, in the microfluidic chip detection platform, a plurality of through holes are uniformly distributed on the placement platform at intervals.
Optionally, in the microfluidic chip detection platform, the through holes are circular holes, and the diameter of each circular hole is between 1 mm and 10 mm.
The technical scheme provided by the utility model has the following advantages:
1. the utility model provides a microfluidic chip detection platform, which comprises a placement platform, a first magnetic field generator and a first lifting mechanism, wherein the first magnetic field generator can generate a first magnetic field, and the placement platform is positioned in the first magnetic field; the first lifting mechanism is provided with a first driving piece, the installation end of the first driving piece is connected with the placement platform, and the driving end of the first driving piece is connected with the first magnetic field generator; the first driving piece can drive the first magnetic field generator to be far away from or close to the placing platform so as to adjust the first magnetic field distribution.
According to the microfluidic chip detection platform with the structure, the microfluidic chips are placed on the placement platform, and the first driving piece enables the first magnetic field generator to be lifted, so that the first magnetic field is changed, the microfluidic chips are detected at the same time, and the working efficiency of the microfluidic chip detection platform is improved.
2. According to the microfluidic chip detection platform provided by the utility model, the plurality of through holes are formed in the placement platform, so that the microfluidic chips are inserted into the through holes, and the placement platform is only required to be transferred without separate transfer of the microfluidic chips, so that quantitative transfer of the microfluidic chips is realized.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present utility model, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
FIG. 1 is an explosion schematic diagram of a microfluidic chip detection platform provided by the utility model;
FIG. 2 is a schematic diagram of a placement platform provided by the microfluidic chip detection platform of the present utility model;
FIG. 3 is a schematic diagram of another embodiment of a placement platform provided by the microfluidic chip detection platform of the present utility model;
fig. 4 is a schematic diagram of a third embodiment of a placement platform provided by the microfluidic chip detection platform according to the present utility model.
Reference numerals illustrate:
1. placing a platform; 11. a through hole;
2. a first magnetic field generator;
31. a first driving member; 32. a first screw rod; 33. a first guide bar;
4. a second magnetic field generator;
51. a second driving member; 52. a second screw rod; 53. and a second guide bar.
Detailed Description
The following description of the embodiments of the present utility model will be made apparent and fully in view of the accompanying drawings, in which some, but not all embodiments of the utility model are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
In the description of the present utility model, it should be noted that the directions or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.
In addition, the technical features of the different embodiments of the present utility model described below may be combined with each other as long as they do not collide with each other.
Example 1
The embodiment provides a micro-fluidic chip detection platform, as shown in fig. 1 to 4, which comprises a placement platform 1, a first magnetic field generator 2 and a first lifting mechanism, wherein the first magnetic field generator 2 can generate a first magnetic field, and the placement platform 1 is positioned in the first magnetic field; the first lifting mechanism is provided with a first driving piece 31, the installation end of the first driving piece 31 is fixedly connected with the placement platform 1, and the driving end of the first driving piece 31 is connected with the first magnetic field generator 2; the first drive 31 is capable of driving the first magnetic field generator 2 away from or towards the placement platform 1 to adjust the first magnetic field distribution.
According to the microfluidic chip monitoring platform provided by the embodiment, the microfluidic chips are placed on the placement platform 1, and the first driving piece 31 is used for enabling the first magnetic field generator 2 to be lifted, so that the first magnetic field is changed, the microfluidic chips are detected at the same time, and the working efficiency of the microfluidic chip monitoring platform is improved.
As shown in fig. 1 to 4, in the micro-fluidic chip detection platform provided in this embodiment, the placement platform 1 is a rectangular plate, as an alternative embodiment, a person skilled in the art may adjust the shape of the placement platform 1, the placement platform 1 is fixed on a laboratory platform by bolts, the thickness of the placement platform 1 is 5 mm, as an alternative embodiment, a person skilled in the art may adjust the thickness of the placement platform 1 as required. The placing platform 1 is provided with a plurality of through holes 11, the bottom of the microfluidic chip is provided with pins, the pins are inserted into the through holes 11 and used for fixing the microfluidic chip on the placing platform 1, the through holes 11 are uniformly and alternately distributed on the placing platform 1, the distance between the through holes 11 is 10 millimeters, and as an alternative implementation mode, the distance between the through holes 11 can be adjusted according to the needs of a person in the field; in practical application, the through hole 11 is a circular hole, and the diameter of the circular hole is 5 mm, in one embodiment, the through hole 11 may also be a square hole, the side length of the square is 5 mm, in another embodiment, the through hole 11 may also be a regular hexagon hole, and the inscribed circle of the regular hexagon has a diameter of 5 mm. The placing platform 1 is provided with a plurality of through holes 11, each microfluidic chip is inserted into the plurality of through holes 11, and the placing platform 1 is only required to be transferred without carrying out independent transfer of the microfluidic chips, so that quantitative transfer of the plurality of microfluidic chips is realized.
As shown in fig. 1, the microfluidic chip detection platform provided in this embodiment further includes a first screw rod 32 and a first guide rod 33, where the first magnetic field generator 2 is configured to generate a first magnetic field, the first magnetic field generator 2 is a neodymium magnet, the first driving member 31 is a motor, the mounting seat of the first driving member 31 is fixedly connected with the placement platform 1 through a bolt, the first screw rod 32 has a smooth end and a threaded end, the smooth end of the first screw rod 32 is fixedly connected with the driving end of the first driving member 31, i.e. the lower part of the first screw rod 32 is connected with the driving end of the first driving member 31 through a key, the upper part of the first screw rod 32 penetrates out of the first magnetic field generator 2, the threaded end of the first screw rod 32 is in threaded connection with the first magnetic field generator 32, and the first screw rod 32 penetrates through the first magnetic field generator 32 and protrudes out of the first magnetic field generator 32; the lower part of the first guide rod 33 is welded and fixed with the top surface of the placement platform 1, the upper part of the first guide rod 33 passes through the first magnetic field generator 2 and extends out of the first magnetic field generator, the first magnetic field generator 2 can slide along the axial direction of the first guide rod 33, and in practical application, the first guide rod 33 is provided with three, and the three first guide rods 33 and the first screw rods 32 are distributed at four corners of the placement platform 1. The first driving member 31 drives the first screw rod 32 to rotate, and the first magnetic field generator 2 moves along the axial direction of the first screw rod 32 because the first screw rod 32 is in threaded connection with the first magnetic field generator 2.
As shown in fig. 1, the microfluidic chip detection platform provided in this embodiment further includes a second magnetic field generator 4 and a second lifting mechanism, the second magnetic field generator 4 is configured to generate a magnetic field, the second magnetic field generator 4 is a neodymium magnet, the second lifting mechanism includes a second driving member 51, a second lead screw 52 and a second guide rod 53, the second driving member 51 is a motor, a mounting seat of the second driving member 51 is fixedly connected with the placement platform 1 through a bolt, the second lead screw 52 has an optical end and a threaded end, the upper portion of the second lead screw 52 is a smooth end, the lower portion of the second lead screw 52 is a threaded end, the smooth end of the second lead screw 52 is connected with the second driving member 51 through a key, the threaded end of the second lead screw 52 penetrates out of the second magnetic field generator 4 and is in threaded connection with the second magnetic field generator, the upper end of the second guide rod 53 is welded with the bottom surface of the placement platform 1, the lower end of the second guide rod 53 penetrates through the second magnetic field generator 4, the second magnetic field generator 4 can slide along the second guide rod 53, in practical application, three second guide rods 53 are provided, and the three second guide rods 53 are distributed on the bottom surface of the second lead screw 52 and the second lead screw 1 and are symmetrically placed on the second lead screw 1, and the second lead screw 52 is rotatably arranged on the placement platform through the second guide platform 1.
The working process of the microfluidic chip detection platform provided by the embodiment is as follows:
the pins of the microfluidic chips are inserted into the through holes 11 on the placement platform 1, then the first driving piece 31 is started, the first driving piece 31 drives the first screw rod 32 to rotate, the first screw rod 32 is in threaded fit with the first magnetic field generator 2, the first screw rod 32 enables the distance between the first magnetic field generator 2 and the placement platform 1 to change, namely, the first magnetic field generator 2 moves along the axial direction of the first guide rod 33, so that the first magnetic field changes, meanwhile, the second driving piece 51 rotates, the second driving piece 51 drives the second screw rod 52 to rotate, the second screw rod 52 enables the distance between the second magnetic field generator 4 and the placement platform 1 to change, namely, the second magnetic field generator 4 moves along the axial direction of the second guide rod 53, so that the second magnetic field changes, the placement platform 1 is placed in the first magnetic field and the second magnetic field, and the microfluidic chips complete detection through the continuously changing magnetic fields.
It is apparent that the above examples are given by way of illustration only and are not limiting of the embodiments. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. While still being apparent from variations or modifications that may be made by those skilled in the art are within the scope of the utility model.

Claims (9)

1. A microfluidic chip detection platform, comprising:
a placement platform (1), wherein the placement platform (1) is suitable for placing a plurality of microfluidic chips;
a first magnetic field generator (2), the first magnetic field generator (2) being capable of generating a first magnetic field, and a placement platform (1) being located within the first magnetic field;
the first lifting mechanism is provided with a first driving piece (31), the installation end of the first driving piece (31) is fixedly connected with the placement platform (1), and the driving end of the first driving piece (31) is connected with the first magnetic field generator (2);
the first driving member (31) is capable of driving the first magnetic field generator (2) away from or towards the placement platform (1) to adjust the first magnetic field variation.
2. The microfluidic chip detection platform according to claim 1, wherein the first lifting mechanism comprises:
the first screw rod (32), one end of the first screw rod (32) is fixedly connected with the driving end of the first driving piece (31), and the other end of the first screw rod (32) is in threaded connection with the first magnetic field generator (2).
3. The microfluidic chip detection platform according to claim 2, wherein the first lifting mechanism further comprises at least one first guide rod (33), one end of the first guide rod (33) is fixedly connected with the placement platform (1), and the other end of the first guide rod (33) is slidably connected with the first magnetic field generator (2).
4. The microfluidic chip detection platform according to any one of claims 1-3, further comprising:
-a second magnetic field generator (4), the second magnetic field generator (4) being capable of generating a second magnetic field, and the placement platform (1) being located within the second magnetic field;
the second lifting mechanism is provided with a second driving piece (51), the installation end of the second driving piece (51) is fixedly connected with the placement platform (1), and the driving end of the second driving piece (51) is connected with the second magnetic field generator (4);
the second driving member (51) is capable of driving the second magnetic field generator (4) away from or towards the placement platform (1) to adjust the second magnetic field variation.
5. The microfluidic chip detection platform according to claim 4, wherein the second lifting mechanism comprises:
and one end of the second screw rod (52) is fixedly connected with the driving end of the second driving piece (51), and the other end of the second screw rod (52) is in threaded connection with the second magnetic field generator (4).
6. The microfluidic chip detection platform according to claim 5, wherein the second lifting mechanism further comprises at least one second guide rod (53), one end of the second guide rod (53) is fixedly connected with the placement platform (1), and the other end of the second guide rod (53) is slidably connected with the second magnetic field generator (4).
7. The microfluidic chip detection platform according to claim 6, wherein a plurality of through holes (11) are formed in the placement platform (1), and the through holes (11) are suitable for being inserted with the microfluidic chip.
8. The microfluidic chip detection platform according to claim 7, wherein a plurality of the through holes (11) are uniformly spaced on the placement platform (1).
9. The microfluidic chip detection platform according to claim 8, wherein the through holes (11) are circular holes, and the diameter of the circular holes is between 1 mm and 10 mm.
CN202223048682.2U 2022-11-16 2022-11-16 Micro-fluidic chip detection platform Active CN218917279U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116200241A (en) * 2022-12-13 2023-06-02 呼和浩特君源精测科技有限公司 Tumor marker detection platform and application method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116200241A (en) * 2022-12-13 2023-06-02 呼和浩特君源精测科技有限公司 Tumor marker detection platform and application method thereof

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