CN218846581U - Biological sample access arrangement and biological sample storage device - Google Patents

Biological sample access arrangement and biological sample storage device Download PDF

Info

Publication number
CN218846581U
CN218846581U CN202223450312.1U CN202223450312U CN218846581U CN 218846581 U CN218846581 U CN 218846581U CN 202223450312 U CN202223450312 U CN 202223450312U CN 218846581 U CN218846581 U CN 218846581U
Authority
CN
China
Prior art keywords
sample
sample storage
transfer mechanism
vertical direction
storage rack
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202223450312.1U
Other languages
Chinese (zh)
Inventor
胡佳霖
黄轶
张铭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Base Biotechnology Chengdu Co ltd
Original Assignee
Base Biotechnology Chengdu Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Base Biotechnology Chengdu Co ltd filed Critical Base Biotechnology Chengdu Co ltd
Priority to CN202223450312.1U priority Critical patent/CN218846581U/en
Application granted granted Critical
Publication of CN218846581U publication Critical patent/CN218846581U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The utility model relates to a biological sample access arrangement and biological sample storage equipment, the biological sample access arrangement comprises a transfer mechanism, a sample storage rack, a horizontal motion driving mechanism and a rotary motion driving mechanism, wherein, the transfer mechanism is respectively connected with the horizontal motion driving mechanism and the rotary motion driving mechanism; a sample temporary storage space for placing the sample box is arranged on the transfer mechanism; a sample storage rack is provided with a sample placing space for placing a sample box; the height position of the sample placement space in the vertical direction is located at a height position where the transfer mechanism is butted against. Can follow the rotatory and transfer mechanism along horizontal direction reciprocating motion of the parallel axis of vertical direction through the setting, can realize depositing the sample box in sample storage frame or take out from sample storage frame, simple structure not only, the space occupies fewly moreover, is favorable to the miniaturized design of product.

Description

Biological sample access arrangement and biological sample storage device
Technical Field
The application relates to the field of low-temperature storage, in particular to a biological sample access device and biological sample storage equipment.
Background
Since the lower the temperature, the slower the biochemical reaction speed of the biological sample and the longer the time for storing the biological sample, the biological sample is usually stored in a cryopreservation tube of a sample box before the sample box is stored in a biological sample storage device having a low temperature environment therein, so as to implement low temperature storage of the biological sample.
To access the sample cartridges, the biological sample storage device is typically provided with a refrigerator, a sample storage rack inside the refrigerator for placing the sample cartridges, and a docking mechanism for docking the sample cartridges with the outside of the biological sample storage device. In the existing biological sample storage device, the docking mechanism and the refrigerator are usually far away from each other, and in order to transfer the sample box between the docking mechanism and the sample storage rack, a transfer mechanism for transferring the sample box with a complicated structure needs to be arranged between the docking mechanism and the sample storage rack.
For example, in the technical solution disclosed in the utility model publication No. CN209027170U, the cryogenic storage device includes a refrigerator mechanism, a transfer box transfer mechanism, a three-dimensional moving clamping mechanism, and a fixed base, wherein the refrigerator mechanism is disposed at one side in a frame structure of the fixed base; the transfer mechanism of the transfer box is arranged at the other side in the frame structure of the fixed base and is used for transferring the transfer box for placing the sample box inside and outside; the three-dimensional moving clamping mechanism is arranged above the refrigerator mechanism and used for storing and taking the sample box and the freezing storage tube. The transfer mechanism of the transfer box comprises a base, two guide plates, a transfer box containing plate, a front door plate and a front door driving mechanism, and not only is the structure complex, but also the occupied space is large.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides a biological sample access arrangement for overcome among the prior art in order to be located the inside sample storage frame of refrigerator and access the sample box, need set up the technical problem of the comparatively complicated transfer mechanism of structure.
The first aspect of the embodiment of the application discloses a biological sample storing and taking device, which comprises a transfer mechanism, a sample storage rack, a horizontal motion driving mechanism and a rotary motion driving mechanism, wherein the transfer mechanism is respectively connected with the horizontal motion driving mechanism and the rotary motion driving mechanism, and a sample temporary storage space for placing a sample box is arranged on the transfer mechanism; a sample storage rack is provided with a sample placing space for placing a sample box; the height position of the sample placing space in the vertical direction is located at a height position in abutment with the transfer mechanism. When the rotary motion driving mechanism drives the transfer mechanism to rotate along an axis parallel to the vertical direction and enables the transfer mechanism to face the sample storage rack, the horizontal motion driving mechanism drives the transfer mechanism to move along a direction perpendicular to the vertical direction so as to transfer a sample box from the sample temporary storage space into the sample placing space or transfer the sample box from the sample placing space into the sample temporary storage space. When the rotary motion driving mechanism drives the transfer mechanism to rotate along an axis parallel to the vertical direction and enables the transfer mechanism to rotate by a preset angle, the horizontal motion driving mechanism drives the transfer mechanism to move along a direction perpendicular to the vertical direction.
In an optional embodiment of the present invention, the rotary motion driving mechanism includes a first motor, and an output shaft of the first motor is connected to the transfer mechanism and the horizontal motion driving mechanism; when the output shaft of the first motor rotates, the transfer mechanism and the horizontal motion driving mechanism are driven to rotate along the axis parallel to the vertical direction.
In an optional embodiment of the present invention, at least two sample support members with different heights are disposed on the sample storage rack along a vertical direction, and the sample support members are provided with the sample placing spaces; the biological sample access device also comprises a lifting mechanism, when the lifting mechanism is connected with the sample storage rack, the lifting mechanism drives the sample storage rack to move along the vertical direction relative to the transfer mechanism, so that one sample placing space is positioned at the height position in butt joint with the transfer mechanism.
In an optional embodiment of the present invention, the lifting mechanism includes a lifting connecting member and a telescopic assembly disposed along a vertical direction, wherein the lifting connecting member is connected to the telescopic assembly; under the action of driving force, the length of the telescopic assembly in the vertical direction changes, so that the lifting connecting piece is driven to move in the vertical direction relative to the sample storing and taking mechanism.
The utility model discloses an optional embodiment, elevating system includes the fourth motor, it includes the couple to promote the connecting piece, the first end of couple with the output shaft of fourth motor, whole all be equipped with the connecting piece on the sample storage frame. When the fourth motor drives the hook to rotate by a first preset angle along a first rotating direction, the second end of the hook is connected with the connecting piece of the sample storage rack. When the fourth motor drives the hook to rotate for a second preset angle along a second rotation direction, the second end of the hook is disconnected with the connecting piece of the sample storage rack; wherein the first and second rotational directions are opposite rotational directions.
In an optional embodiment of the present invention, the lifting mechanism further comprises a contact piece, a first limit switch and a second limit switch; an output shaft of the fourth motor is connected with the contact piece; the first limit switch and the second limit switch are installed on the telescopic assembly along the movement direction of the contact piece. When the fourth motor drives the contact piece to rotate by the first preset angle along a first rotation direction, the contact piece is contacted with the first limit switch, so that the fourth motor stops rotating; when the fourth motor drives the contact piece to rotate by the second preset angle along the second rotation direction, the contact piece is in contact with the second limit switch, so that the fourth motor stops rotating.
In an optional embodiment of the present invention, the number of the sample storage racks is plural, one of the plural sample storage racks is a target lifting rack, and the lifting mechanism is detachably connected to all the sample storage racks; the biological sample access device also comprises an adjusting mechanism which is connected with all the sample storage racks; when the adjusting mechanism adjusts the target lifting frame to a horizontal position connected with the lifting mechanism, the lifting mechanism and the target lifting frame are connected or disconnected.
In an optional embodiment of the present invention, the adjusting mechanism includes a rotating frame and a rotating shaft; all the sample storage racks are positioned on the rotating rack; the rotating shaft is arranged along the vertical direction and is connected with the rotating frame; the rotating shaft drives the rotating frame to rotate relative to the lifting mechanism along an axis parallel to the vertical direction under the action of driving force, and the target lifting frame is adjusted to be in a horizontal position connected with the lifting mechanism.
In an optional embodiment of the present invention, the rotating rack includes a bottom plate, a top plate and a supporting member, and the sample storage rack is placed on the bottom plate; the top plate passes through support piece is in the top of bottom plate, be equipped with on the top plate and supply sample storage rack dodges the hole along vertical direction passing.
A second aspect of embodiments of the present application discloses a biological sample storage apparatus, comprising a biological sample access device and a refrigerator as described in the first aspect above; wherein, the first and the second end of the pipe are connected with each other, the interior of the refrigerator is a low-temperature storage space; the sample storage rack is located inside the low-temperature storage space, and the transfer mechanism, the horizontal motion driving mechanism and the rotary motion driving mechanism are located inside or outside the low-temperature storage space.
The utility model discloses biological sample access arrangement deposits the sample box in sample storage frame or takes out from sample storage frame including transferring mechanism, sample storage frame, horizontal motion actuating mechanism and rotary motion actuating mechanism through the rotary motion and the horizontal motion that transfer the mechanism. In the prior art, as in the utility model with CN209027170U, in order to store or take out the sample box, a transfer box transfer mechanism is provided in addition to a three-position movable clamping mechanism similar to the transfer mechanism for storing and taking out the sample box and freezing the storage tube, and the structure of the transfer box transfer mechanism is complicated. Therefore, the utility model discloses a technical scheme need not to set up prior art transfer case transmission device, just can realize depositing in or taking out the sample box. Therefore compared with the prior art, the utility model provides a biological sample access arrangement is simple structure not only, and the space occupies fewly moreover, is favorable to the miniaturized design of product.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a schematic structural diagram of a biological sample access device according to an embodiment of the present disclosure;
FIG. 2 is a schematic diagram of a biological sample access device according to an alternative embodiment provided in the examples of the present application;
FIG. 3 is a schematic structural diagram of a biological sample access device according to an alternative embodiment provided in the examples of the present application;
FIG. 4 is a schematic structural diagram of an alternative embodiment of a biological sample access device provided in the examples of the present application;
FIG. 5 is a schematic structural diagram of a biological sample storage device according to an embodiment of the disclosure;
FIG. 6 is a perspective view schematically illustrating the structure of a biological sample storage device according to an embodiment of the present disclosure;
FIG. 7 is a schematic structural diagram of a biological sample storage device according to an alternative embodiment disclosed in the examples of the present application;
FIG. 8 is a schematic perspective view of an alternative embodiment of a biological specimen storage device as disclosed in the examples herein;
fig. 9 is a schematic structural diagram of an alternative embodiment of a door opening mechanism provided in an example of the present application;
fig. 10 is a schematic structural diagram of an alternative embodiment of a door opening mechanism provided in an example of the present application.
Reference numerals: 1-a docking mechanism; 2-a transfer mechanism; 3-a horizontal motion drive mechanism; 4-a rotary motion drive mechanism; 41-a first motor; 42-a mounting seat; 5-a lifting mechanism; 51-a fourth motor; 52-lifting the link; 52 a-hook; 52 b-first positioning member; 53-contact patch; 53 a-first connecting tab; 53 b-second connecting piece; 54-a first limit switch; 55-a second limit switch; 56-a telescoping assembly; 6-an adjusting mechanism; 61-a rotating frame; 61 a-a bottom plate; 61 b-a support frame; 61b 1-top plate; 61b 2-support; 62-a rotating shaft; 63-a third motor; 7-a cover opening mechanism; 71-a first drive mechanism; 72-a second drive mechanism; 73-heat preservation upper cover; 74-a third drive mechanism; 8, a refrigerator; 9-sample storage rack.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
In the present invention, the terms "upper", "lower", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings. These terms are used primarily to better describe the invention and its embodiments, and are not intended to limit the indicated devices, elements or components to a particular orientation or to be constructed and operated in a particular orientation.
Moreover, some of the above terms may be used to indicate other meanings besides the orientation or positional relationship, for example, the term "on" may also be used to indicate some kind of attachment or connection relationship in some cases. The specific meaning of these terms in the present invention can be understood by those of ordinary skill in the art as appropriate.
Furthermore, the terms "mounted," "disposed," "provided," and "connected" are to be construed broadly. For example, it may be a fixed connection, a removable connection, or a unitary construction; can be a mechanical connection, or an electrical connection; may be directly connected, or indirectly connected through intervening media, or may be in internal communication between two devices, elements or components. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
Furthermore, the terms "first," "second," and the like are used primarily to distinguish one device, element, or component from another (the specific type and configuration of the device may be the same or different), and are not used to indicate or imply the relative importance or number of the indicated devices, elements, or components. "plurality" means two or more unless otherwise specified.
Example one
As shown in fig. 1-8, the embodiment of the utility model discloses a biological sample access arrangement, include: the device comprises a transfer mechanism 2, a sample storage rack 9, a horizontal motion driving mechanism 3 and a rotary motion driving mechanism 4, wherein the transfer mechanism 2 is respectively connected with the horizontal motion driving mechanism 3 and the rotary motion driving mechanism 4, and a sample temporary storage space for placing a sample box is arranged on the transfer mechanism 2; a sample storage rack 9 is provided with a sample placing space for placing a sample box; the height position of the sample placement space in the vertical direction is located at a height position where the transfer mechanism 2 is butted. When the rotary motion driving mechanism 4 drives the transfer mechanism 2 to rotate along the axial direction parallel to the vertical direction and makes the transfer mechanism 2 face the sample storage rack 9, the horizontal motion driving mechanism 3 drives the transfer mechanism 2 to move along the direction perpendicular to the vertical direction so as to transfer the sample box from the sample temporary storage space into the sample placing space or transfer the sample box from the sample placing space into the sample temporary storage space. When the rotary motion driving mechanism 4 drives the transfer mechanism 2 to rotate along an axis parallel to the vertical direction and rotates the transfer mechanism 2 by a preset angle, the horizontal motion driving mechanism 3 drives the transfer mechanism 2 to move in a direction perpendicular to the vertical direction.
In this embodiment, the biological sample access device is part of a biological sample storage device for transferring a sample cartridge between the interior and the exterior of the biological sample storage device. The biological sample storage apparatus includes a biological sample access device and a refrigerator 8, the refrigerator 8 has a low-temperature storage space accommodating a plurality of sample storage shelves 9 therein, and a low-temperature environment can be generated in the low-temperature storage space. Wherein, the low temperature environment refers to the environment with the temperature of-80 ℃ or below-80 ℃, and the biological sample can be preserved in the environment to reduce the biochemical reaction of the biological sample and keep the stability of various components in the biological sample.
In this embodiment, the sample storage rack 9 is used for placing sample cartridges to be stored, and a sample placing space for placing one or more sample cartridges is provided on the sample storage rack 9.
The sample storage rack 9 is not limited in structural composition, shape and size, and can be set correspondingly according to actual application requirements. For example, the sample storage rack 9 may include one or more sample supports, and the space above the sample supports is the sample placing space.
In this embodiment, the transfer mechanism 2 is used for storing the sample cartridge into the sample storage rack 9 or taking the sample cartridge out of the sample storage rack 9, and a sample temporary storage space for placing the sample cartridge is provided on the transfer mechanism 2. In addition, the specific structure, shape, size and installation position of the transfer mechanism 2 are not limited, and can be set correspondingly according to the actual application requirements. For example, a transfer support plate for supporting the sample box may be disposed on the transfer mechanism 2, and the space above the transfer support plate is a sample temporary storage space.
In the present embodiment, the horizontal movement driving mechanism 3 is connected to the transfer mechanism 2 for providing a driving force for movement of the transfer mechanism 2 in a direction perpendicular to the vertical direction so that the transfer mechanism 2 can reciprocate on a plane perpendicular to the vertical direction. The specific structural composition of the horizontal movement driving mechanism 3, the installation position relative to the transfer mechanism 2, and the generation mode of the driving force are not limited, and can be set correspondingly according to the actual application requirements. For example, the horizontal movement driving mechanism 3 may be a component that generates a driving force manually, or may be a component that generates a driving force by electric power or magnetic force.
In the present embodiment, a rotational movement driving mechanism 4 is connected to the transfer mechanism 2 for providing a driving force for the rotational movement of the transfer mechanism 2 so that the transfer mechanism 2 can rotate along an axis parallel to the vertical direction.
The specific configuration of the rotational drive mechanism 4, the mounting position with respect to the transfer mechanism 2, and the manner of generating the drive force are not limited. For example, the rotational motion driving mechanism 4 may be a component that generates a driving force manually, or may be a component that generates a driving force by electric power or magnetic force.
In this embodiment, the specific manner in which the transfer mechanism 2 transfers the sample cartridge to the outside of the refrigerator 8 is not particularly limited, and the transfer mechanism 2 may directly transfer the sample cartridge placed in the sample temporary storage space to the outside of the refrigerator 8; the sample box placed in the sample temporary storage space can also be indirectly transferred to the outside of the refrigerator 8, that is, the sample box placed in the sample temporary storage space is firstly transferred to the docking mechanism 1 for realizing interaction with a user, and then the docking mechanism 1 is subjected to docking operation to transfer the sample box to the outside of the refrigerator 8.
In addition, the value of the preset angle of rotation of the transfer mechanism 2 can be determined according to the docking position of the transfer mechanism 2 and the sample storage rack 9, and the docking position of the transfer mechanism 2 and the outside of the refrigerator 8 or the docking mechanism 1, and specific numerical values are not limited. When the transfer mechanism 2 faces the sample storage rack 9, the transfer mechanism 2 can face the outside of the refrigerator 8 or the docking mechanism 1 after rotating for a preset angle along the first rotating direction, and further move along the direction perpendicular to the vertical direction, so as to access the sample box from the outside of the refrigerator 8 or the docking mechanism 1; when the transfer mechanism 2 faces the outside of the refrigerator 8 or the docking mechanism 1, the transfer mechanism 2 may face the sample storage rack 9 after rotating by a preset angle in a second rotation direction opposite to the first rotation direction, and further move in a direction perpendicular to the vertical direction to access the sample cartridge from the sample storage rack 9.
Further, it is also preferable that the docking position of the transfer mechanism 2 with the sample storage rack 9 and the docking position with the outside of the refrigerator 8 or with the docking mechanism 1 are respectively located at opposite sides, and the value of the preset angle may be set to 180 degrees, so that the object to be docked can be adjusted by rotating 180 degrees regardless of which direction the transfer mechanism 2 is rotated.
In this embodiment, the process of transferring the sample cartridge to the sample storage rack 9 is as follows: the rotary motion driving mechanism 4 drives the transfer mechanism 2 to rotate so that the transfer mechanism 2 rotates by a preset angle; the transfer mechanism 2 reciprocates forwards and backwards once along the direction vertical to the vertical direction under the driving of the horizontal movement driving mechanism 3, so that a user can place a sample box in a sample temporary storage space conveniently; then the transfer mechanism 2 is rotated by the rotational movement driving mechanism 4 so that the transfer mechanism 2 faces the sample storage rack 9, i.e., so that the sample temporary storage space of the transfer mechanism 2 is opposed to the sample placement space of the sample storage rack 9; the transfer mechanism 2 is then reciprocated once forward and backward in a direction perpendicular to the vertical direction with respect to the sample storage rack 9 by the horizontal movement driving mechanism 3 to transfer the sample cartridge in the sample buffer space into the sample placing space, i.e., to transfer the sample cartridge onto the sample storage rack 9, so that the sample cartridge can be placed in the refrigerator 8 for storage by using the sample storage rack 9.
In this embodiment, the process of taking out the sample cartridge from the sample storage rack 9 is as follows: the rotary motion driving mechanism 4 drives the transfer mechanism 2 to rotate so that the transfer mechanism 2 faces the sample storage rack 9, i.e., so that the sample temporary storage space of the transfer mechanism 2 is opposed to the sample placement space of the sample storage rack 9; the transfer mechanism 2 reciprocates forwards and backwards relative to the sample storage rack 9 in a direction perpendicular to the vertical direction once under the drive of the horizontal movement drive mechanism 3 to transfer the sample cartridge in the sample placing space into the sample temporary storage space; then the transfer mechanism 2 is driven by the rotary motion driving mechanism 4 to rotate, so that the transfer mechanism 2 rotates by a preset angle; then the transfer mechanism 2 reciprocates forwards and backwards once along the direction vertical to the vertical direction under the driving of the horizontal movement driving mechanism 3, so that a user can take the sample box conveniently.
Optionally, in order to improve the interaction experience of the user, the biological sample access device further includes a docking mechanism 1, and an external docking space for placing the sample box is provided on the docking mechanism 1; when the rotary motion driving mechanism 4 drives the transfer mechanism 2 to rotate along an axis parallel to the vertical direction and makes the transfer mechanism 2 face the docking mechanism 1, the horizontal motion driving mechanism 3 drives the transfer mechanism 2 to move along a direction perpendicular to the vertical direction so as to transfer the sample box from the inside of the sample temporary storage space to the outside of the docking space or transfer the sample box from the inside of the outside of the docking space to the inside of the sample temporary storage space.
The docking mechanism 1 is used for realizing the interaction between the biological sample storage device and a user, namely, realizing the transfer of the sample box between the inside and the outside of the biological sample storage device, and the user can place or transfer the sample box on the docking mechanism 1 from the outside of the biological sample storage device and take the sample box placed on the docking mechanism 1 away.
Further, the docking mechanism 1 is provided with an external docking space for placing a cartridge to be stored or a cartridge to be taken out. The structure composition, shape and size of the docking mechanism 1 are not limited, and can be set correspondingly according to the actual application requirements. For example, a docking support plate for supporting the sample box may be disposed on the docking mechanism 1, and the space above the docking support plate is an external docking space.
The process of transferring the sample cartridge from the docking mechanism 1 to the sample storage rack 9 is as follows: placing a sample box to be stored in an external docking space of the docking mechanism 1, and driving the transfer mechanism 2 to rotate by the rotary motion driving mechanism 4 so that the transfer mechanism 2 faces the docking mechanism 1, i.e. so that at least one sample temporary storage space of the transfer mechanism 2 is opposite to the external docking space of the docking mechanism 1; the transfer mechanism 2 reciprocates forwards and backwards relative to the docking mechanism 1 in a direction perpendicular to the vertical direction once under the drive of the horizontal movement driving mechanism 3 so as to transfer the sample box positioned in the external docking space into the sample temporary storage space; then the transfer mechanism 2 is rotated by the rotational movement driving mechanism 4 so that the transfer mechanism 2 faces the sample storage rack 9, i.e., so that the sample temporary storage space of the transfer mechanism 2 is opposed to the sample placement space of the sample storage rack 9; then, the transfer mechanism 2 reciprocates forward and backward in a direction perpendicular to the vertical direction with respect to the sample storage rack 9 once by the driving of the horizontal movement driving mechanism 3 to transfer the sample cartridge in the sample temporary storage space into the sample placing space, i.e., to transfer the sample cartridge onto the sample storage rack 9, so that the sample cartridge can be placed in the refrigerator 8 for storage by using the sample storage rack 9.
The process of transferring the sample cartridge from the sample storage rack 9 to the docking mechanism 1 is as follows: the rotary motion driving mechanism 4 drives the transfer mechanism 2 to rotate so that the transfer mechanism 2 faces the sample storage rack 9, i.e., so that the sample temporary storage space of the transfer mechanism 2 is opposed to the sample placement space of the sample storage rack 9; the transfer mechanism 2 reciprocates once forward and backward in a direction perpendicular to the vertical direction with respect to the sample storage rack 9 under the drive of the horizontal movement drive mechanism 3 to transfer the sample cartridge in the sample placing space into the sample temporary storage space; then the transfer mechanism 2 is driven by the rotary motion driving mechanism 4 to rotate, so that the transfer mechanism 2 faces the docking mechanism 1, namely, the sample temporary storage space of the transfer mechanism 2 is opposite to the external docking space of the docking mechanism 1; then the transfer mechanism 2 reciprocates forward and backward relative to the docking mechanism 1 in a direction perpendicular to the vertical direction once under the driving of the horizontal movement driving mechanism 3 to transfer the sample cartridge located in the sample temporary storage space into the external docking space, that is, transfer the sample cartridge onto the docking mechanism 1, so that the user can further take the sample cartridge out of the biological sample storage device.
Alternatively, referring to fig. 1, in order to automate the rotational movement of the transfer mechanism 2 along its horizontal plane, the rotational movement driving mechanism 4 may comprise a first motor 41, and an output shaft of the first motor 41 is connected to the transfer mechanism 2 and the horizontal movement driving mechanism 3. When the output shaft of the first motor 41 rotates, the transfer mechanism 2 and the horizontal movement drive mechanism 3 are driven to rotate along the axis parallel to the vertical direction.
The first motor 41 is configured to drive the transfer mechanism 2 and the horizontal movement driving mechanism 3 to rotate along an axis parallel to the vertical direction, so that the sample placing space of the transfer mechanism 2 can be respectively opposite to the sample placing space of the sample storage rack 9 and the external docking space of the docking mechanism 1. The connection mode of the first motor 41, the transfer mechanism 2 and the horizontal movement driving mechanism 3, and the power of the first motor 41 are not limited, and can be set accordingly according to the actual application requirements.
Further, the output shaft of the first motor 41 may be directly or indirectly connected to the transfer mechanism 2 and the horizontal movement driving mechanism 3. For example, the output shaft of the first motor 41 may be directly connected to the transfer mechanism 2 and the horizontal movement drive mechanism 3, respectively; the transfer mechanism 2 can also be connected with the output shaft of the first motor 41 and the horizontal motion driving mechanism 3; or the horizontal motion driving mechanism 3 is connected with the output shaft of the first motor 41 and the transfer mechanism 2; alternatively, the output shaft of the first motor 41 is indirectly connected to the transfer mechanism 2 and the horizontal movement driving mechanism 3 through the mounting mechanism.
Further, the rotary motion driving mechanism 4 may further include a mounting seat 42, and the transfer mechanism 2 and the horizontal motion driving mechanism 3 are mounted on the mounting seat 42, and the mounting seat 42 is connected to an output shaft of the first motor 41. When the output shaft of the first motor 41 rotates, the mounting seat 42 may rotate the transfer mechanism 2 and the horizontal movement driving mechanism 3 in the same direction or in the opposite direction to the rotation direction of the output shaft of the first motor 41.
Wherein, by mounting the transfer mechanism 2 and the horizontal movement driving mechanism 3 on the mounting seat 42 together, the first motor 41 can drive the transfer mechanism 2 and the horizontal rotation driving mechanism to rotate more smoothly, and the connection of the transfer mechanism 2 and the horizontal rotation driving mechanism can be made more stable. The shape, size and material of the mounting seat 42 are not limited, and can be set accordingly according to the actual application requirements.
Optionally, in order to facilitate management of the sample cartridges stored in the biological sample storage device, barcode information for identifying or tracing the sample cartridges may be provided on the sample cartridges, and correspondingly, the biological sample access device may further include a barcode scanning mechanism (not shown) facing the docking mechanism 1. When the sample box is positioned on the docking mechanism 1, the barcode scanning mechanism can identify barcode information on the sample box.
The code scanning mechanism can identify the bar code information of the sample box placed on the docking mechanism 1, and perform information identification and recording on the sample box to be stored in the biological sample storage device or the sample box taken out of the biological sample storage device so as to perform intelligent management on the sample box. In addition, the installation position of the code scanning mechanism is not limited, but it is required to ensure that the code scanning mechanism can read and obtain the barcode information on the sample cartridge when the sample cartridge is located in the external docking space of the docking mechanism 1.
Optionally, in order to increase the number of sample cartridges that can be placed, at least two sample supports with different heights are vertically disposed on the sample storage rack 9, and a sample placing space for placing the sample cartridges is disposed on each sample support.
Optionally, the biological sample access device may further include a lifting mechanism 5, and when the lifting mechanism 5 is connected to the sample storage rack 9, the lifting mechanism 5 is configured to drive the sample storage rack 9 to move in a vertical direction relative to the transfer mechanism 2, so that one sample placement space is located at a height position where it is docked with the transfer mechanism 2.
Among them, because among the prior art, if the sample box stacks up from top to bottom in refrigerator 8, when will be followed the top of sample box and will be located a certain sample box on top layer and take out, need earlier to shift the sample box that is located its top in proper order, just can take out this sample box, lead to the inefficiency of taking out of sample box. This embodiment is through setting up elevating system 5, when elevating system 5 is connected with sample storage rack 9, elevating system 5 can drive sample storage rack 9 and remove along vertical direction for transfer mechanism 2, thereby can place the high position adjustment in space to the high position with transfer mechanism 2 butt joint with a sample in sample storage rack 9, be about to the sample place the space highly and sample in vertical direction and keep in the space adaptation, with further place the space with the sample from the sample through transfer mechanism 2 and shift the sample to sample temporary storage space, perhaps shift the sample box to the sample from sample temporary storage space and place the space.
In addition, the specific structure, shape and size of the lifting mechanism 5 and the connection mode of the lifting mechanism 5 and the sample storage rack 9 are not limited, and can be set correspondingly according to the actual application requirements. For example, the lifting mechanism 5 and the sample storage rack 9 may be fixedly connected, and the lifting mechanism 5 and the sample storage rack 9 may be detachably connected.
Further, in order to increase the number of sample cartridges that can be stored in the biological sample storage apparatus, a plurality of sample storage racks 9 may be provided, and one or more sample placing spaces may be provided on each sample storage rack 9. When the number of the sample storage racks 9 is plural, in order to simplify the structural complexity of the elevating mechanism 5, it is preferable that the elevating mechanism 5 is detachably connected to all the sample storage racks 9.
Further, in consideration of the fact that different sample storage racks 9 may be placed at different horizontal positions in the low-temperature storage space of the refrigerator 8, that is, different horizontal positions of the different sample storage racks 9 on a plane parallel to the horizontal plane, the horizontal position of the sample storage rack 9 with respect to the elevating mechanism 5 may be adjusted by providing the adjusting mechanism 6 for adjusting the horizontal position so that the horizontal position of the target rack is located at a position where the target rack can be connected to the elevating mechanism 5, that is, the target rack is located at a horizontal position where the elevating mechanism 5 is connected to the elevating mechanism, so that the elevating mechanism 5 can be connected to the target rack by further movement.
Specifically, the biological sample storage and retrieval device further includes an adjustment mechanism 6, and the adjustment mechanism 6 is connected to all the sample storage racks 9; when the adjusting mechanism 6 adjusts the target lifting frame to the horizontal position of the connection with the lifting mechanism 5, the lifting mechanism 5 and the target lifting frame are connected or disconnected, so that the lifting mechanism 5 drives the target lifting frame to move in the vertical direction relative to the transfer mechanism 2.
The specific structure and installation position of the adjusting mechanism 6, the connection mode of all the sample storage racks 9 and the adjusting mechanism 6, and the adjustment mode of the horizontal position of the target lifting frame are not limited, and can be correspondingly set according to actual application requirements. For example, the adjusting mechanism 6 may adjust the horizontal position of the target lifting frame by rotating the rotating structure, or by matching a slide rail and a slider. For another example, the adjustment mechanism 6 may be connected to all the sample storage racks 9 in such a manner that all the sample storage racks 9 are directly placed on the adjustment mechanism 6, or all the sample storage racks 9 may be connected to the adjustment mechanism 6 by a stopper structure or a connecting structure.
Further, referring to fig. 4, the adjusting mechanism 6 may include a rotating frame 61 and a rotating shaft 62. All the sample storage racks 9 are located on the rotary rack 61, the rotary shaft 62 is provided in the vertical direction, and the rotary shaft 62 is connected to the rotary rack 61. The rotating shaft 62 drives the rotating frame 61 to rotate along an axis parallel to the vertical direction with respect to the elevating mechanism 5 under the driving force, and adjusts the target elevating frame to a horizontal position connected to the elevating mechanism 5.
The adjusting mechanism 6 is a structure composed of a rotating shaft 62 and a rotating frame 61, so that the occupied space can be reduced, and the miniaturization design of the whole structure is facilitated. In addition, the installation positions and connection modes of the rotating shaft 62 and the rotating frame 61 are not limited, and can be set accordingly according to the actual application requirements. For example, the rotating shaft 62 may be installed above or below the rotating frame 61, and the rotating shaft 62 may also be embedded in the rotating frame 61.
Further, the rotary rack 61 may include a first fixing mechanism, and the sample storage rack 9 may include a second fixing mechanism; when the sample storage rack 9 is not connected to the elevating mechanism 5, the first fixing mechanism is connected to the second fixing mechanism in a fitting manner to restrict the movement of the sample storage rack 9 with respect to the rotary rack 61.
However, in consideration of the fact that the sample storage rack 9 placed on the rotating rack 61 may move relative to the rotating rack 61 due to inertia if the sample storage rack 9 is not restrained when the rotating rack 61 rotates. Therefore, by providing the first fixing mechanism and the second fixing mechanism which are connected in a fitting manner, the movement of the sample storage rack 9 relative to the rotary rack 61 can be restricted, and the shaking of the sample storage rack 9 and the sample cartridge placed thereon can be reduced.
In addition, the specific structure of the first fixing mechanism and the second fixing mechanism is not limited, and the first fixing mechanism and the second fixing mechanism can be correspondingly arranged according to the actual application requirement. For example, the first fixing structure and the second fixing structure may be respectively provided with a hanging groove and a hanging lug which are adaptive to the shape, the size, the arrangement position and the number, and the rotating rack 61 and the sample storage rack 9 can be matched and connected through the hanging groove and the hanging lug so as to limit the movement of the sample storage rack 9 relative to the rotating rack 61 as much as possible.
Further, referring to fig. 4, in order to automatically rotate the rotating frame 61, the adjusting mechanism 6 may further include a third motor 63, and an output shaft of the third motor 63 is connected to the rotating shaft 62; when the output shaft of the third motor 63 rotates, the rotating shaft 62, the rotating rack 61, and the sample storage rack 9 are driven to rotate along the axis parallel to the vertical direction, so that the horizontal position of the target elevating rack is adjusted to the connection position with the elevating mechanism 5.
The third motor 63 is configured to drive the rotating shaft 62, the rotating frame 61, and the sample storage rack 9 to rotate together along an axis parallel to the vertical direction, so as to adjust the horizontal position of the target lifting frame to the connection position with the lifting mechanism 5, thereby facilitating the connection of the lifting mechanism 5 and the target lifting frame.
In addition, the power, the setting position and the connection mode with the rotating shaft 62 of the third motor 63 are not limited, and may be set accordingly according to the actual application requirements. For example, when the output shaft of the third motor 63 is disposed in the vertical direction, the output shaft of the third motor 63 may be connected to the rotating shaft 62 directly or through a connecting member, and the output shaft of the third motor 63 and the rotating shaft may also be connected through a pair of gears, so that when the output shaft of the third motor 63 rotates, the rotating shaft 62 may drive the rotating frame 61 and the sample storage rack 9 to rotate in the same direction or the opposite direction as the rotating direction of the output shaft of the third motor 63.
Further, in order to prevent the sample storage rack 9 from moving in a direction perpendicular to the vertical direction during the rotation, i.e., to avoid the sample storage rack 9 from shaking with respect to the rotating rack 61, the rotating rack 61 may further include a bottom plate 61a and a support frame 61b mounted on the bottom plate 61 a. When the sample storage rack 9 is disposed on the bottom plate 61a, the support frame 61b may restrict the sample storage rack 9 from moving in a direction perpendicular to the vertical direction.
The bottom plate 61a is used for providing a supporting force for the sample storage rack 9, and the supporting frame 61b is used for limiting the movement of the sample storage rack 9 relative to the bottom plate 61 a. The bottom plate 61a, the support frame 61b, and the sample storage rack 9 are collectively rotatable with respect to the elevating mechanism 5 by the driving force, and the horizontal position of the target elevating rack can be smoothly adjusted to the connection position with the elevating mechanism 5.
In addition, the specific structural composition, size and material of the bottom plate 61a and the supporting frame 61b are not limited, and can be set accordingly according to the actual application requirements. For example, the supporting frame 61b may be a limiting boss structure fixedly disposed on the bottom plate 61a, and the sample storage rack 9 may be placed in a groove formed by the limiting boss structure; or a limiting bracket structure fixedly arranged on the bottom plate 61a, the sample storage rack 9 can be placed in a rack placing space surrounded by the limiting bracket structure, wherein one rack placing space can be used for placing one sample storage rack 9.
Further, the supporting frame 61b comprises a top plate 61b1 and a supporting member 61b2, the top plate 61b1 is arranged on the upper portion of the bottom plate 61a through the supporting member 61b2, and the top plate 61b1 is provided with an avoiding hole for the sample storage rack 9 to pass through in the vertical direction.
Wherein, the plane of the cross section of the sample storage rack 9 is perpendicular to the vertical direction, and the sample storage rack 9 can move along the vertical direction through the avoidance hole which is matched with the cross section shape and the size of the sample storage rack 9 and is arranged on the top plate 61b 1. Through setting up roof 61b1 and support piece 61b2 that have the hole of dodging, not only can restrict sample storage rack 9 jointly and move along the direction perpendicular with vertical direction, the part of roof 61b1 outside dodging the hole can set up to enclosed construction moreover to being equivalent to a certain extent and having added the one deck heat preservation at the top of whole sample storage rack 9, it is better to make the below cold insulation effect of roof 61b 1.
Further, in order to realize the detachable connection with the sample storage rack 9 and improve the space utilization rate, the lifting mechanism 5 may further include a lifting connection member 52 and a telescopic assembly 56 disposed in the vertical direction, wherein the lifting connection member 52 is connected with the telescopic assembly 56; the length of the telescopic assembly 56 in the vertical direction is changed by the driving force to move the lifting link 52 in the vertical direction to the connection position with the sample storage rack 9; after the lifting link 52 is connected to the sample storage rack 9, the telescoping assembly 56 can move the lifting link 52 and the sample storage rack 9 in a vertical direction relative to the transfer mechanism 2.
The specific structure, size, material and number of the lifting connecting member 52 and the telescopic assembly 56 are not limited, and can be set correspondingly according to the actual application requirements. For example, referring to fig. 3, the lifting mechanism 5 may include two lifting links 52 for detachable connection with two sample storage racks 9, respectively. For another example, the lifting connector 52 may be a clamping jaw, and a clamping structure adapted to the clamping jaw may be provided on the sample storage rack 9; the lifting link 52 may be a hook 52a, and the sample storage rack 9 may be provided with a coupling hole of a different shape to be fitted to the hook 52a. For another example, the telescoping assembly 56 may include at least one of a telescoping rod, a double-deck slide rail, and a connecting chain that may vary in length.
Further, referring to fig. 2, in order to automatically connect or disconnect the elevating mechanism 5 to or from the sample storage rack, the elevating mechanism 5 further includes a fourth motor 51, and an output shaft of the fourth motor 51 is connected to the lifting link 52. When the output shaft of the fourth motor 51 rotates, the lifting link 52 is driven to rotate.
Further, it is preferable that the lifting link 52 is a hook 52a, a first end of the hook 52a is connected to an output shaft of the fourth motor 51, and correspondingly, all the sample storage racks 9 are provided with a link adapted to the shape and size of a second end of the hook 52a. When the fourth motor 51 drives the hook 52a to rotate by a first preset angle along the first rotation direction, the second end of the hook 52a can be connected to the connecting member of the sample storage rack, that is, the connection with the sample storage rack 9 is realized. When the fourth motor 51 drives the hook 52a to rotate by a second preset angle along a second rotation direction, the second end of the hook 52a can be disconnected from the connecting member of the sample storage rack 9, i.e., the connection with the sample storage rack 9 is released. Wherein the first and second rotational directions are opposite rotational directions.
The fourth motor 51 is used for providing a driving force for the rotation of the hook 52a, so that the second end of the hook 52a is connected with or disconnected from the connecting member of the sample storage rack 9. Through adopting couple and connecting piece complex structure, not only simple structure is convenient for moreover form and remove the connection in automation.
In addition, the first preset angle and the second preset angle may be equal or unequal; the output shaft of the fourth motor 51 may be directly connected to the first end of the hook 52a or indirectly connected thereto. The power of the fourth motor 51 and the shape, size and material of the hook 52a are not limited, and may be set accordingly according to the actual application requirements. For example, the shape of the hook 52a may be an inverted T shape, an i shape, or a double J shape, and correspondingly, the connecting member may be a connecting hole of a different shape, or a hook 52a of a different shape.
Further, referring to fig. 2, the lifting mechanism 5 further includes a contact piece 53, a first limit switch 54, and a second limit switch 55; an output shaft of the fourth motor 51 is connected with the contact piece 53; a first limit switch 54 and a second limit switch 55 are mounted on the telescopic assembly 56 in the direction of movement of the contact plate 53. When the fourth motor 51 drives the contact piece 53 to rotate by a first preset angle along the first rotation direction, the contact piece 53 contacts with the first limit switch 54, so that the fourth motor 51 stops rotating; when the fourth motor 51 drives the contact piece 53 to rotate by a second preset angle along the second rotation direction, the contact piece 53 contacts with the second limit switch 55, so that the fourth motor 51 stops rotating.
When the contact piece 53 contacts with the first limit switch 54 or the second limit switch 55, the fourth motor 51 stops rotating, so that the situation that the hook 52a and the sample storage rack 9 are not connected well or cannot be disconnected due to the fact that the rotating angle of the hook 52a is too large can be avoided. In addition, the specific structure, size and material of the contact piece 53 are not limited, and may be set according to the actual application requirements.
Further, referring to fig. 2, the contact piece 53 may include a first connection piece 53a and a second connection piece 53b connected thereto. When the fourth motor 51 drives the first connecting piece 53a and the second connecting piece 53b to rotate along the first rotating direction and the first connecting piece 53a contacts with the first limit switch 54, the fourth motor 51 stops rotating, and the rotating angle of the fourth motor 51 is a first preset angle. When the fourth motor 51 drives the first connecting piece 53a and the second connecting piece 53b to rotate along the second rotation direction and the second connecting piece 53b contacts the second limit switch 55, the fourth motor 51 stops rotating, and the rotation angle of the fourth motor 51 is a second preset angle.
Wherein, the contact piece 53 is connected by first connection piece 53a and second connection piece 53b and constitutes, confirms first angle of predetermineeing through the contained angle between first connection piece 53a and the second connection piece 53b, can avoid couple 52a turned angle too big to cause the condition appearance that the linkage effect is not good or can't remove the connection between couple 52a and the sample storage, and because the structure of contact piece 53 is comparatively simple, not only be convenient for carry out production and processing, be convenient for determine first angle of predetermineeing and the second angle of predetermineeing moreover when the assembly.
Further, it is preferable that the hook 52a is an inverted T shape with a simple structure, the hook includes a first portion and a second portion both being elongated, the first portion is placed along the vertical direction, a first end of the first portion is connected with an output shaft of the fourth motor, a second end of the first portion is connected with the second portion, the second portion is perpendicular to the first portion, and correspondingly, elongated connection holes are formed in all the sample storage racks 9.
The second end of the inverted T-shaped hook 52a is in a strip shape, and the specific shape of the cross section is not limited, and can be selected accordingly according to actual requirements. For example, the second end of the inverted-T shaped hook 52a may be a rectangular parallelepiped, an elongated cylinder, or a curved cylinder; correspondingly, the elongated connecting hole can be a cuboid hole or a curved hole.
Further, in order to reduce the rotation angle of the inverted T-shaped hook 52a while the inverted T-shaped hook 52a is connected to the sample storage rack 9 well, it is preferable that both the first preset angle and the second preset angle are 90 degrees.
Further, the lifting connector 52 further comprises a first positioning member 52b, and a second positioning member detachably connected with the first positioning member 52b is arranged above all the sample storage racks 9; when the first positioning member 52b is connected to the second positioning member of the sample storage rack 9, the fourth motor 51 drives the hook 52a to rotate along the first rotation direction or the second rotation direction.
Through the detachable connection of the first positioning member 52b and the second positioning member of the sample storage rack 9, the movement of the sample storage rack 9 relative to the lifting mechanism 5 can be limited in the process of forming or removing the connection between the lifting mechanism 5 and the sample storage rack 9, so as to improve the success rate of the connection between the lifting mechanism 5 and the sample storage rack 9.
In addition, the specific structure, the setting position, the number, the size and the material of the first positioning element 52b and the second positioning element are not limited, and can be correspondingly set according to the actual application requirements. For example, the first positioning member 52b and the second positioning member may be a positioning pin and a positioning hole adapted in shape, size, arrangement position and number, respectively, and the positioning pin and the positioning hole may be one or more pairs, and the lifting connector 52 and the sample storage rack 9 are connected by fitting the positioning pin and the positioning hole, so as to prevent the sample storage rack 9 from moving.
As can be seen from the above description of the present embodiment, the biological sample access device provided in the embodiment of the present application includes a transfer mechanism 2, a sample storage rack 9, a horizontal movement driving mechanism 3, and a rotational movement driving mechanism 4, wherein the transfer mechanism 2 is connected to the horizontal movement driving mechanism 3 and the rotational movement driving mechanism 4 respectively; a sample temporary storage space for placing a sample box is arranged on the transfer mechanism 2; a sample storage rack is provided with a sample placing space for placing a sample box; the height position of the sample placing space in the vertical direction is located at a height position where the sample placing space is butted against the transfer mechanism. The utility model discloses a can follow vertical axis rotation and follow horizontal direction reciprocating motion's transfer mechanism 2, can realize stocking the sample box in sample storage frame 9 or take out from sample storage frame 9, not only simple structure, the space occupies fewly moreover, is favorable to the miniaturized design of product.
Example two
As shown in fig. 1 to 10, the present embodiment discloses a biological sample storage apparatus including a biological sample access device and a refrigerator 8 as described in the first embodiment. Wherein, the inside of the refrigerator 8 is a low-temperature storage space; the sample storage rack 9 is located inside the low-temperature storage space, and the transfer mechanism 2, the horizontal movement driving mechanism 3, and the rotational movement driving mechanism 4 are all located inside or outside the low-temperature storage space.
In this embodiment, the biological sample to be cryopreserved is usually placed in a sample cartridge, the sample cartridge is placed on the sample storage rack 9, and the sample storage rack 9 is stored in the cryogenic storage space of the refrigerator 8. In addition, the material, shape and size of the refrigerator 8 and the low-temperature storage space are not limited, and can be determined according to the actual application requirements.
In this embodiment, the transfer mechanism 2, the horizontal movement driving mechanism 3, and the rotational movement driving mechanism 4 may be located inside the low-temperature storage space or outside the low-temperature storage space, which is not limited in this embodiment. The transfer mechanism 2 is rotated and directed toward the sample storage rack 9 by the rotary motion driving mechanism 4, and then reciprocated once forward and backward in a direction perpendicular to the vertical direction by the horizontal motion driving mechanism 3 to take out the sample cartridge from the sample storage rack 9 or put the sample cartridge into the sample storage rack 9.
Optionally, an opening is provided on the refrigerator 8, and the biological sample storage device may further include a lid opening mechanism 7 mounted on the refrigerator 8, the lid opening mechanism 7 being configured to open or close the opening; when the cover opening mechanism 7 is in an open state, the internal environment of the refrigerator 8 can be communicated with the external environment, so that the sample box can be stored in the refrigerator 8, or the sample box can be taken out from the refrigerator 8; when the opening in the refrigerator 8 is in a closed state, the door opening mechanism 7 can insulate the internal environment and the external environment of the refrigerator 8.
Wherein, through setting up uncap mechanism 7, can be so that when need not to deposit and withdraw the sample box, seal the opening on the refrigerator 8 to make 8 insides of refrigerator have better cold insulation effect.
Further, referring to fig. 9, in order to automatically open or close the opening of the refrigerator 8, the lid opening mechanism 7 may include a first driving mechanism 71, a second driving mechanism 72, and a heat-insulating upper lid 73, the heat-insulating upper lid 73 is disposed above the opening of the refrigerator 8, the first driving mechanism 71 is connected to the second driving mechanism 72 and the heat-insulating upper lid 73, the heat-insulating upper lid 73 may be movable in a vertical direction with respect to the refrigerator 8 by the first driving mechanism 71, and the first driving mechanism 71 may be reciprocally movable in a direction perpendicular to the vertical direction with respect to the refrigerator 8 by the second driving mechanism 72 to close or open the opening of the refrigerator 8. Wherein the first drive mechanism 71 and the second drive mechanism 72 each generate a drive force by electric power.
In order to obtain a better cold insulation effect, the size of the upper heat insulation cover 73 needs to be matched with the opening of the refrigerator 8, and the material of the upper heat insulation cover 73 is selected as the material with better heat insulation performance as far as possible.
Further, the biological sample storage device may include a first displacement sensor and a second displacement sensor, and the first driving mechanism 71 may further include a sensing block adapted to the first displacement sensor and the second displacement sensor.
The horizontal moving stroke of the first driving mechanism 71 can be determined by the distance between the first displacement sensor and the second displacement sensor, and the specific setting positions of the first displacement sensor and the second displacement sensor are not limited and can be reasonably set according to actual application requirements. The horizontal movement distance of the first driving mechanism 71 can be controlled by providing the first displacement sensor and the second displacement sensor to further control the opening and closing degree of the opening of the insulated container by the insulated upper cover 73.
Further, referring to fig. 10, in order to automatically open or close the opening of the refrigerator 8, the cover opening mechanism 7 may further include a third driving mechanism 74 and a heat insulating upper cover 73, the heat insulating upper cover 73 is disposed above the opening of the refrigerator 8, the third driving mechanism 74 is connected to one side of the heat insulating upper cover 73, and the heat insulating upper cover 73 may be rotated relative to the refrigerator 8 by the driving of the third driving mechanism 74 to close or open the opening of the refrigerator 8. Wherein the third drive mechanism 74 generates a drive force by electric power.
The embodiments in the present specification are described in a progressive manner, and the same or similar parts in the embodiments are referred to each other, and each embodiment focuses on the differences from the other embodiments.
The above are merely examples of the present application and are not intended to limit the present application. Numerous modifications and variations will readily occur to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the scope of the claims of the present application.

Claims (10)

1. A biological sample storing and taking device is characterized by comprising a transfer mechanism, a sample storage rack, a horizontal motion driving mechanism and a rotary motion driving mechanism,
the transfer mechanism is respectively connected with the horizontal motion driving mechanism and the rotary motion driving mechanism, and a sample temporary storage space for placing a sample box is arranged on the transfer mechanism; a sample storage rack is provided with a sample placing space for placing a sample box; the height position of the sample placing space in the vertical direction is located at the height position butted with the transfer mechanism;
when the rotating motion driving mechanism drives the transfer mechanism to rotate along an axis parallel to the vertical direction and enables the transfer mechanism to face the sample storage rack, the horizontal motion driving mechanism drives the transfer mechanism to move along a direction perpendicular to the vertical direction so as to transfer a sample box from the sample temporary storage space into the sample placing space or transfer the sample box from the sample placing space into the sample temporary storage space;
when the rotary motion driving mechanism drives the transfer mechanism to rotate along an axis parallel to the vertical direction and enables the transfer mechanism to rotate by a preset angle, the horizontal motion driving mechanism drives the transfer mechanism to move along a direction perpendicular to the vertical direction.
2. The biological specimen access device of claim 1, wherein the rotational motion drive mechanism includes a first motor having an output shaft coupled to the transfer mechanism and the horizontal motion drive mechanism; when the output shaft of the first motor rotates, the transfer mechanism and the horizontal motion driving mechanism are driven to rotate along the axis parallel to the vertical direction.
3. The device for storing and taking a biological sample according to claim 1, wherein the sample storage rack is provided with at least two sample supports having different heights along a vertical direction, and the sample support is provided with the sample placing space; the biological sample access device also comprises a lifting mechanism, when the lifting mechanism is connected with the sample storage rack, the lifting mechanism drives the sample storage rack to move along the vertical direction relative to the transfer mechanism, so that one sample placing space is positioned at the height position in butt joint with the transfer mechanism.
4. The biological specimen access device of claim 3, wherein the lift mechanism includes a lift link and a telescoping assembly disposed in a vertical direction, wherein:
the lifting connecting piece is connected with the telescopic assembly; under the action of driving force, the length of the telescopic assembly in the vertical direction changes, so that the lifting connecting piece is driven to move in the vertical direction relative to the sample storing and taking mechanism.
5. The device according to claim 4, wherein the lifting mechanism comprises a fourth motor, the lifting link comprises a hook, a first end of the hook is connected to an output shaft of the fourth motor, and all the sample storage racks are provided with a link;
when the fourth motor drives the hook to rotate for a first preset angle along a first rotating direction, the second end of the hook is connected with the connecting piece of the sample storage rack;
when the fourth motor drives the hook to rotate for a second preset angle along a second rotation direction, the second end of the hook is disconnected with the connecting piece of the sample storage rack; wherein the first and second rotational directions are opposite rotational directions.
6. The biological specimen access device of claim 5, wherein the lift mechanism further comprises a contact pad, a first limit switch, and a second limit switch;
an output shaft of the fourth motor is connected with the contact piece; the first limit switch and the second limit switch are arranged on the telescopic assembly along the movement direction of the contact piece;
when the fourth motor drives the contact piece to rotate by the first preset angle along a first rotation direction, the contact piece is contacted with the first limit switch, so that the fourth motor stops rotating; when the fourth motor drives the contact piece to rotate by the second preset angle along the second rotation direction, the contact piece is in contact with the second limit switch, so that the fourth motor stops rotating.
7. The biological sample access device of claim 3, wherein the sample storage rack is multiple in number, one of the multiple sample storage racks is a target lift rack, and the lift mechanism is removably attachable to all of the sample storage racks; the biological sample access device also comprises an adjusting mechanism, and the adjusting mechanism is connected with all the sample storage racks;
when the adjusting mechanism adjusts the target lifting frame to a horizontal position connected with the lifting mechanism, the lifting mechanism and the target lifting frame are connected or disconnected.
8. The biological specimen access device of claim 7, wherein the adjustment mechanism includes a rotating rack and a rotating shaft; all the sample storage racks are positioned on the rotating rack; the rotating shaft is arranged along the vertical direction and is connected with the rotating frame; the rotating shaft drives the rotating frame to rotate relative to the lifting mechanism along an axis parallel to the vertical direction under the action of driving force, and the target lifting frame is adjusted to be in a horizontal position connected with the lifting mechanism.
9. The biological sample access device of claim 8, wherein the carousel comprises a bottom plate, a top plate, and a support, the sample storage rack resting on the bottom plate; the top plate passes through the support piece is arranged above the bottom plate, and the top plate is provided with an avoiding hole for the sample storage rack to penetrate through in the vertical direction.
10. A biological sample storage device comprising the biological sample access apparatus of any one of claims 1 to 9 and a refrigerator; wherein, the interior of the refrigerator is a low-temperature storage space; the sample storage rack is located inside the low-temperature storage space, and the transfer mechanism, the horizontal motion driving mechanism and the rotary motion driving mechanism are located inside or outside the low-temperature storage space.
CN202223450312.1U 2022-12-22 2022-12-22 Biological sample access arrangement and biological sample storage device Active CN218846581U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223450312.1U CN218846581U (en) 2022-12-22 2022-12-22 Biological sample access arrangement and biological sample storage device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223450312.1U CN218846581U (en) 2022-12-22 2022-12-22 Biological sample access arrangement and biological sample storage device

Publications (1)

Publication Number Publication Date
CN218846581U true CN218846581U (en) 2023-04-11

Family

ID=87305520

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223450312.1U Active CN218846581U (en) 2022-12-22 2022-12-22 Biological sample access arrangement and biological sample storage device

Country Status (1)

Country Link
CN (1) CN218846581U (en)

Similar Documents

Publication Publication Date Title
US6688123B2 (en) Automated storage and retrieval apparatus for freezers and related method thereof
KR20200135462A (en) Automated cryogenic storage and withdrawal system
WO2021169148A1 (en) Cryogenic storage and retrieval apparatus and cryogenic storage and retrieval method
CN101320045A (en) Stacker
CN218846581U (en) Biological sample access arrangement and biological sample storage device
EP3006867B1 (en) Low-temperature storage device with rotating lock chamber
CN111907942A (en) Liquid nitrogen storage device and using method thereof
CN111907943A (en) Liquid nitrogen storage device with automatic access function
CN219346889U (en) Biological sample access device and biological sample storage equipment
CN219340273U (en) Freezing box storing and taking device
CN115109687A (en) Microbial community inoculation device
CN115843785A (en) Biological sample low temperature storage device
CN217837466U (en) Article transfer device
CN111731743A (en) Intelligent refrigeration house
CN218218933U (en) Freezing box butt joint module and low temperature storage device
CN218967858U (en) Low-temperature transfer operation mechanism for biological samples
CN218909006U (en) Freezing box taking and placing device
CN218930297U (en) Sample box taking and placing device and low-temperature storage equipment
CN220728603U (en) Refrigerator for storing biological samples
CN219340589U (en) Sample frame driving device and sample box low-temperature storage equipment
CN113428553A (en) Vertical automatic cabinet
CN115843786B (en) Low-temperature storage device for biological samples
CN115790037A (en) Biological sample cryogenic storage device
CN113879822A (en) Storing and taking device and method for frozen storage box
CN208606457U (en) Cryogenic storage system

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant