CN218793884U

CN218793884U - High-efficient recovery and regeneration device of organic solvent for heparin sodium extraction

Info

Publication number: CN218793884U
Application number: CN202221174012.2U
Authority: CN
Inventors: 丁雪达; 丁卫平; 王林红
Original assignee: Yangzhou Jinli Biotechnology Co ltd
Current assignee: Yangzhou Jinli Biotechnology Co ltd
Priority date: 2022-05-17
Filing date: 2022-05-17
Publication date: 2023-04-07
Anticipated expiration: 2032-05-17

Abstract

The utility model provides a regenerating unit is retrieved with high efficiency to organic solvent for heparin sodium extraction, the on-line screen storage device comprises a base, be equipped with recovery unit on the base, recovery unit includes evaporating pot, condenser pipe and collecting box, be equipped with the support on being close to the stand of connecting pipe one end, the condenser pipe is placed on the support, condenser pipe one end is linked together with the connecting pipe, and the other end is linked together with the collecting box, the one end of stand is kept away from on the base to the collecting box setting, be equipped with the hot plate on the evaporating pot inner wall, the inside filter plate that is equipped with in evaporating pot top, through recovery unit, from annotating the liquid mixture that the liquid mouth filling needs the recovery, through the hot plate heating liquid on the evaporating pot inner wall, the inside alcohol of mixed liquid volatilizees fast alcohol steam, gets into the condenser pipe from the connecting pipe in, finally flows into to the collecting box, collects the purification from the alcohol of retrieving from the liquid outlet of collecting box, has realized the recycle of alcohol, has improved the utilization efficiency of alcohol, saves the cost.

Description

High-efficient recovery and regeneration device of organic solvent for heparin sodium extraction

Technical Field

The utility model relates to a heparin sodium production technical field especially relates to a heparin sodium extraction is with high-efficient regenerating unit that retrieves of organic solvent.

Background

Heparin sodium is the most widely used anticoagulant in clinical settings and appears as a complex with proteins in the body. This complex has no anticoagulant activity and only when isolated alone can exhibit anticoagulant activity. Heparin sodium is widely distributed in the biological field and exists in lung tissues and intestinal tissues of higher mammals such as pigs, cows, sheep and the like, and has very high medicinal value, the heparin sodium is generally subjected to the process steps of scraping intestines, enzymolysis, adsorption, desorption, precipitation and the like during production, wherein the precipitation process refers to the step of adding alcohol into eluent obtained by desorbing and exchanging resin adsorbed with heparin by using saline water in the desorption process and precipitating the heparin sodium in the eluent after stirring, and the alcohol adopted in the process needs to be recycled after recovery so as to improve the alcohol utilization efficiency and save the cost.

SUMMERY OF THE UTILITY MODEL

In order to overcome the defects of the prior art, the utility model provides a heparin sodium extraction is with high-efficient regeneration unit of retrieving of organic solvent.

The utility model discloses a following technical scheme realizes:

the efficient recycling device for the organic solvent for heparin sodium extraction comprises a base, wherein the base is provided with a recycling device, the recycling device comprises an evaporating pot, a condensing pipe and a collecting box, the base is provided with two stand columns, the evaporating pot is arranged between the two stand columns, the left side wall and the right side wall of the evaporating pot are provided with fixing rods, one end of each fixing rod is fixed on the evaporating pot, the other end of each fixing rod is fixed on the inner side wall of the stand column, the top of the evaporating pot is provided with a liquid injection port, and the side edge of the liquid injection port is provided with a connecting pipe;

the stand column close to one end of the connecting pipe is provided with a support, the condensing pipe is placed on the support, one end of the condensing pipe is communicated with the connecting pipe, the other end of the condensing pipe is communicated with the collecting box, and the collecting box is arranged at one end, far away from the stand column, of the base;

the inner wall of the evaporation tank is provided with a heating plate, the upper end of the evaporation tank is provided with a thermometer, and a filter screen plate is arranged inside the top end of the evaporation tank.

The bottom of the evaporation tank is provided with a stirring motor, the output end of the stirring motor is provided with a stirring shaft, the side wall of the stirring shaft is provided with a plurality of groups of stirring blades, the stirring blades are distributed at equal intervals, a stirring rod is arranged on a group of stirring blades at the bottommost end of the stirring shaft, and one end of the stirring rod is fixed on the stirring blades.

The condenser pipe is a spiral through pipe, a valve is arranged between the connecting pipe and the condenser pipe, and a liquid outlet is formed in the side wall of the collecting box.

The collecting box is characterized in that a window is arranged on the wall of the collecting box, a plurality of universal wheels are arranged at the lower end of the base, handrails are arranged on the side wall of the upright column close to the liquid injection port, and reinforcing ribs are arranged between the handrails and the upright column.

The utility model discloses for prior art passes through recovery unit, from annotating the mixed liquid that liquid mouth filling needs to be retrieved, through the hot plate heating liquid on the evaporating pot inner wall, the inside alcohol of mixed liquid volatilizees fast alcohol steam, enters into the condenser pipe from the connecting pipe, finally flows into to the collection incasement, collects the purification from the alcohol of the liquid outlet with retrieving of collection case, has realized the recycle of alcohol, has improved the utilization efficiency of alcohol, saves the cost.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is an enlarged view of the structure at A in FIG. 1;

in the figure: 1. a base; 11. a column; 12. a handrail; 13. reinforcing ribs; 14. a support; 15. a universal wheel; 2. a recovery unit; 21. fixing the rod; 22. a liquid injection port; 23. heating plates; 24. a connecting pipe; 3. a stirring motor; 31. a stirring shaft; 32. stirring blades; 33. a stirring rod; 4. a condenser tube; 41. a valve; 5. a collection box; 51. a window; 52. and a liquid outlet.

Detailed Description

The present invention will be further described with reference to the accompanying drawings and the detailed description, and it should be noted that the embodiments or technical features described below can be arbitrarily combined to form a new embodiment without conflict.

The present invention will be further explained with reference to the accompanying drawings,

as shown in fig. 1-2, an efficient recycling device for organic solvent used for heparin sodium extraction comprises a base 1, wherein the base 1 is provided with a recycling device 2, the recycling device 2 comprises an evaporating pot, a condensing pipe 4 and a collecting box 5, the base 1 is provided with two upright posts 11, the evaporating pot is arranged between the two upright posts 11, the left and right side walls of the evaporating pot are provided with fixing rods 21, one end of each fixing rod 21 is fixed on the evaporating pot, the other end of each fixing rod is fixed on the inner side wall of each upright post 11, the top of the evaporating pot is provided with a liquid injection port 22, and the side of the liquid injection port 22 is provided with a connecting pipe 24;

a support 14 is arranged on the upright post 11 close to one end of the connecting pipe 24, the condenser pipe 4 is placed on the support 14, one end of the condenser pipe 4 is communicated with the connecting pipe 24, the other end of the condenser pipe 4 is communicated with the collecting box 5, and the collecting box 5 is arranged at one end, far away from the upright post 11, of the base 1;

be equipped with hot plate 23 on the evaporating pot inner wall, the upper end of evaporating pot is equipped with the thermometer, the inside filter plate that is equipped with in evaporating pot top, the thermometer is convenient for the reading, makes things convenient for staff's operation, and the filter plate at top filters the impurity of large granule, improves the purity of retrieving alcohol.

The evaporating pot bottom is equipped with agitator motor 3, agitator motor 3's output is equipped with (mixing) shaft 31 be equipped with multiunit stirring leaf 32 on (mixing) shaft 31's the lateral wall, the even equidistance of stirring leaf 32 distributes, be equipped with stirring rod 33 on a set of stirring leaf 32 of (mixing) shaft 31 bottom, stirring rod 33 one end is fixed on stirring leaf 32, and stirring leaf 32 and stirring rod 33 can be with the liquid intensive mixing that needs the recovery for the device heats more evenly rather than for, improves the collection efficiency of alcohol.

The condenser pipe 4 is a spiral through pipe, the valve 41 is arranged between the connecting pipe 24 and the condenser pipe 4, the side wall of the collecting box 5 is provided with the liquid outlet 52, the condenser pipe 4 is made into a spiral shape to increase the transmission path of the alcohol steam, the alcohol steam is cooled, and the collecting efficiency of the device is improved.

Be equipped with window 51 on the 5 walls of collecting box, the lower extreme of base 1 is equipped with a plurality of universal wheels 15, be equipped with handrail 12 on the lateral wall of the stand 11 that is close to annotating liquid mouth 22, be equipped with stiffening rib 13 between handrail 12 and the stand 11, window 51 on the collecting box 5 is made for transparent glass, is convenient for observe how much the alcohol of retrieving in the collecting box 5, in time discharges the alcohol in the collecting box 5, and the base 1 lower extreme sets up universal wheel 15, and through promoting handrail 12 transportation of facilitating the device, universal wheel 15 is from taking self-lock device, and when using, the avoiding device rocks, improves the stability of device.

The utility model discloses a theory of use is: when the device is used, mixed liquid is filled into the evaporation tank from the liquid filling port 22, the valve 41 of the oil filling port is closed, the heating plate 23 on the inner wall of the evaporation tank is opened at the moment, the indication number of the thermometer is observed, the temperature in the evaporation tank is kept around the boiling point of alcohol, the valve 41 on the connecting pipe 24 is opened, and alcohol steam enters the condensation pipe 4 along with the connecting pipe 24 and finally flows into the collecting box 5.

The above embodiments are only preferred embodiments of the present invention, and the protection scope of the present invention cannot be limited thereby, and any insubstantial changes and substitutions made by those skilled in the art based on the present invention are all within the protection scope of the present invention.

Claims

1. The utility model provides a heparin sodium extraction is with high-efficient recovery regenerating unit of organic solvent, includes base (1), be equipped with recovery unit (2) on base (1), its characterized in that: the recovery device (2) comprises an evaporation tank, a condensation pipe (4) and a collection box (5), two upright posts (11) are arranged on the base (1), the evaporation tank is arranged between the two upright posts (11), fixing rods (21) are arranged on the left side wall and the right side wall of the evaporation tank, one end of each fixing rod (21) is fixed on the evaporation tank, the other end of each fixing rod is fixed on the inner side wall of each upright post (11), a liquid injection port (22) is formed in the top of the evaporation tank, and a connecting pipe (24) is arranged on the side edge of the liquid injection port (22);

a support (14) is arranged on the upright post (11) close to one end of the connecting pipe (24), the condensing pipe (4) is placed on the support (14), one end of the condensing pipe (4) is communicated with the connecting pipe (24), the other end of the condensing pipe is communicated with the collecting box (5), and the collecting box (5) is arranged at one end, far away from the upright post (11), of the base (1);

the inner wall of the evaporation tank is provided with a heating plate (23), the upper end of the evaporation tank is provided with a thermometer, and a filter screen plate is arranged inside the top end of the evaporation tank.

2. The device for efficiently recycling and regenerating the organic solvent for heparin sodium extraction according to claim 1, is characterized in that: the evaporating pot bottom is equipped with agitator motor (3), the output of agitator motor (3) is equipped with (mixing) shaft (31), be equipped with multiunit stirring leaf (32) on the lateral wall of (mixing) shaft (31), stirring leaf (32) even equidistance distributes, be equipped with stirring rod (33) on a set of stirring leaf (32) of bottom on (mixing) shaft (31), stirring rod (33) one end is fixed on stirring leaf (32).

3. The device for efficiently recycling and regenerating the organic solvent for heparin sodium extraction according to claim 2, characterized in that: the condenser pipe (4) is a spiral through pipe, a valve (41) is arranged between the connecting pipe (24) and the condenser pipe (4), and a liquid outlet (52) is formed in the side wall of the collecting box (5).

4. The device for efficiently recycling and regenerating the organic solvent for heparin sodium extraction according to claim 1, is characterized in that: the collecting box is characterized in that a window (51) is arranged on the wall of the collecting box (5), a plurality of universal wheels (15) are arranged at the lower end of the base (1), handrails (12) are arranged on the side wall of the upright post (11) close to the liquid injection port (22), and reinforcing ribs (13) are arranged between the handrails (12) and the upright post (11).