CN218636146U - Brain stereotaxic instrument for tracing nerve loop - Google Patents

Abstract

The utility model discloses a brain stereotaxic instrument for neural loop tracing, which comprises a workbench and a fixed panel fixedly arranged at the upper end of the workbench; further comprising: spacing panel, the symmetry is fixed ann in the upper end of workstation, and the operator presses connection shell motion, two the upper end of spacing panel is provided with jointly and is used for carrying out spacing fixed subassembly to the laboratory mouse, under the cooperation of connecting shell, connecting rod, slide bar, first spring, elasticity hemisphere, extension rod, ball, arc recess, probe rod and imaging unit, forms interference fit, and imaging unit can carry out the rotation of small range at the duct of laboratory mouse. This brain stereotaxic apparatus is used in neural loop tracer can reach and detect the formation of image to it under the prerequisite of not injuring the laboratory mouse ear, easy operation, convenient to use.

Description

Brain stereotaxic instrument for neural loop tracing

Technical Field

The utility model relates to a neurobiology field specifically is a brain stereotaxic apparatus is used in neural circuit spike.

Background

In the fields of neuroanatomy, neurophysiology, neuropharmacology, neurosurgery and the like, when the brain functions of various experimental animals are researched, an electrode must be correctly inserted into a target part under the cortex and the position of the electrode is kept not to move, so the brain must be fixed in the test process, and a currently commonly used fixing instrument is a brain positioning instrument (stereotaxic instrument). Different types of brain positioning (fixation) devices are designed for different animals. Specifically, the three-dimensional coordinate system defined by the marks or other reference points outside the skull is used to determine the position of some nerve structures in the subcortical layer so as to carry out directional stimulation, damage, medicine injection, electric potential guidance and other researches under the condition of non-direct-view exposure. Can be used for the research of Parkinson's disease animal model establishment, epilepsy animal model establishment, brain tumor model establishment, learning and memory, brain neural stem cell transplantation, cerebral ischemia and the like.

The neural circuit is for tracer brain stereotaxic instrument like CN215192572U, includes the brain locater body, the symmetry is provided with two ear centre gripping subassemblies on the brain locater body, be provided with the supersound imaging unit that is used for brain formation of image on the ear centre gripping subassembly. The utility model has the advantages of, through setting up brain imaging unit at ear's centre gripping subassembly to show brain information on imaging system, can effectively assist the user and correctly look for the brain district, reduce experimental error, raise the efficiency.

However, although the ear of the laboratory mouse can be prevented from being damaged by the buffer layer, the ear rod and the imaging unit are directly inserted into the ear of the laboratory mouse, the ear channel of the laboratory mouse has the phenomenon of bending, twisting and twisting, the imaging unit cannot move to a certain extent when entering the ear, certain damage can be caused in the detection process,

we therefore propose a neural circuit tracking brain stereotaxic apparatus to address the problems set out above.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a brain stereotaxic apparatus is used in neural loop tracer to solve that above-mentioned background art provides though can prevent through the buffer layer that the laboratory mouse ear from causing the damage, ear stick and formation of image unit are the disect insertion entering at the ear that enters into the laboratory mouse, can cause the damage of ear.

In order to achieve the above object, the utility model provides a following technical scheme: a neural circuit tracing brain stereotaxic instrument comprises a workbench and a fixed panel fixedly arranged at the upper end of the workbench;

further comprising:

the limiting panels are symmetrically and fixedly arranged at the upper end of the workbench, the upper ends of the two limiting panels are provided with fixing components for limiting the laboratory mouse together, and the two limiting panels are provided with ear detection components;

ear detection subassembly sets up the connecting cylinder shell on spacing panel including sliding, movable pore has been seted up on the connecting cylinder shell, it is provided with the connecting rod to alternate in the movable pore, the intercommunication has the arc recess on the lateral wall in movable pore, the arc recess internalization is provided with the ball, the lower extreme fixed mounting of ball has the probe rod, the one end of probe rod is provided with the formation of image unit, be provided with the linkage unit on the spacing panel, the elastic hemisphere of one end symmetry fixed mounting of connecting cylinder shell.

Through adopting above-mentioned technical scheme, under the cooperation of connecting shell, arc recess, connecting rod, ball, probe rod, elasticity hemisphere and imaging unit, the damage of duct can not cause simultaneously to the detection of laboratory mouse duct that can be convenient.

Preferably, the connecting unit includes that symmetry fixed mounting has a slide bar at the equal fixed mounting in upper end of stopper on the lateral wall of spacing panel inner chamber, the both ends of connecting the cartridge case all slide to set up on the slide bar that corresponds the position, two all cup jointed first spring on the slide bar, the both ends of first spring respectively with the lateral wall of stopper, the lateral wall fixed connection of connecting the cartridge case.

Through adopting above-mentioned technical scheme, under the cooperation of stopper, slide bar and first spring, connect cartridge case extensible certain length, the position before can recovering being extrudeed simultaneously.

Preferably, fixed subassembly is including installing the screw thread post in spacing panel upper end admittedly respectively, the upper end threaded connection of screw thread post has rotatory handle, two all slide on the axial lateral wall of screw thread post and be provided with the bracing piece, two the one end of bracing piece is connected with first arc jointly, the upper end fixed mounting of workstation has the second arc board, the second arc board is located first arc board under, the screw thread post has cup jointed the third spring, the both ends of third spring respectively with the lateral wall of bracing piece, spacing panel's upper end fixed connection.

Through adopting above-mentioned technical scheme, under the cooperation of bracing piece, first arc, screw thread post, third spring and second arc, can carry on spacingly to the neck that not unidimensional laboratory mouse advances.

Preferably, the fixed panel is provided with an anti-bite component;

prevent stinging and close the subassembly including first restriction board and the second restriction board of difference fixed mounting on fixed panel, it is provided with splint to slide on the first restriction board, the connecting hole has all been seted up on splint and the second restriction board, be provided with buffering subassembly on the first restriction board.

By adopting the technical scheme, the experimental mouse is prevented from biting the tongue of the experimental mouse under the matching of the second limiting plate, the clamping plate and the connecting hole.

Preferably, the buffering subassembly includes the slide bar of symmetry fixed mounting on first limiting plate, the mounting groove has been seted up to the symmetry on the first limiting plate, two slide bar fixed mounting is in the mounting groove that corresponds the position, splint slide to set up on the slide bar that corresponds the position, two all cup jointed the second spring on the slide bar, two the both ends of second spring respectively with the mounting groove diapire that corresponds the position, the lateral wall fixed connection of splint.

Through adopting above-mentioned technical scheme, under the cooperation of slide bar and second spring, can let the least reserve certain activity space of laboratory mouse.

Compared with the prior art, the beneficial effects of the utility model are that: the imaging unit can rotate in a small amplitude in the auditory canal of the laboratory mouse, so that the detection imaging can be carried out on the auditory canal of the laboratory mouse on the premise of not damaging the ear of the laboratory mouse, the operation is simple, the use is convenient, and the specific contents are as follows;

1. the operator presses the motion of connecting the cartridge shell, connects cartridge shell, connecting rod, slide bar, first spring, elasticity hemisphere, connects pole, ball, arc recess, probe rod and imaging unit's cooperation under, forms interference fit, and imaging unit can carry out the rotation of small range at laboratory mouse's duct, can reach and detect the formation of image to it under the prerequisite of not injuring laboratory mouse ear, easy operation, convenient to use.

2. The operator breaks off with the fingers and thumb going on of laboratory mouse and places second limiting plate and splint in laboratory mouse's mouth, overlaps the tooth cover of laboratory mouse in corresponding the connecting hole, and when laboratory mouse revived the mouth and stings, splint can slide on the slide bar that corresponds the position, and splint can extrude the second spring simultaneously, prevents that laboratory mouse oneself from stinging the tongue, has reached the effect that lets laboratory mouse's mouth have certain cushioning effect.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is an enlarged view of the point A in FIG. 1 according to the present invention;

FIG. 3 is a plan sectional view of the ear detection assembly of the present invention;

FIG. 4 is a schematic view of the fixing assembly of the present invention;

FIG. 5 is an enlarged view of the point B in FIG. 1 according to the present invention;

fig. 6 is a plan sectional view of the joint of the clamping plate and the first limiting plate of the present invention.

In the figure: 1. a work table; 2. fixing the panel; 3. a limiting panel; 4. a fixing component; 41. a support bar; 42. a first arc-shaped plate; 43. a threaded post; 44. rotating the handle; 45. a third spring; 46. a second arc plate; 5. an anti-bite assembly; 51. a first limiting plate; 52. connecting holes; 53. a splint; 54. a second limiting plate; 55. a buffer assembly; 551. mounting grooves; 552. a second spring; 553. a slide bar; 6. an ear detection assembly; 61. connecting the cylinder shell; 62. a connecting rod; 63. an arc-shaped groove; 64. a ball bearing; 65. a probe rod; 66. an elastic hemisphere; 67. an imaging unit; 68. a movable duct; 69. a connection unit; 691. a limiting block; 692. a slide bar; 693. a first spring.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-3, the present invention provides a technical solution: a neural circuit tracing brain stereotaxic instrument comprises a workbench 1 and a fixed panel 2 fixedly arranged at the upper end of the workbench 1; further comprising: spacing panel 3, the symmetry is fixed ann in the upper end of workstation 1, and the upper end of two spacing panels 3 is provided with jointly and is used for carrying out spacing fixed subassembly 4 to the laboratory mouse, all is provided with ear detection subassembly 6 on two spacing panels 3.

Ear detection subassembly 6 sets up connecting cylinder shell 61 on spacing panel 3 including sliding, movable pore 68 has been seted up on connecting cylinder shell 61, it is provided with connecting rod 62 to alternate in the movable pore 68, the intercommunication has arc recess 63 on movable pore 68's the lateral wall, the activity is provided with ball 64 in the arc recess 63, ball 64's lower extreme fixed mounting has probe rod 65, probe rod 65's one end is provided with imaging unit 67, imaging unit 67 external display device (for drawing in the picture), be provided with coupling unit 69 on spacing panel 3, the elastic hemisphere 66 of one end symmetry fixed mounting of connecting cylinder shell 61. Under the cooperation of connecting barrel shell 61, arc recess 63, connecting rod 62, ball 64, probe 65, elasticity hemisphere 66 and imaging unit 67, can be convenient to the measuring of laboratory mouse's auditory canal, can not cause the damage of auditory canal simultaneously.

The connection unit 69 includes that symmetry fixed mounting has a stopper 691 on the lateral wall of 3 inner chambers of spacing panel, and the equal fixed mounting in upper end of two stoppers 691 has slide bar 692, and the both ends of connecting cartridge case 61 all slide to set up on the slide bar 692 that corresponds the position, have all cup jointed first spring 693 on two slide bar 692, first spring 693's both ends respectively with the lateral wall of stopper 691, the lateral wall fixed connection of connecting cartridge case 61. The connection cartridge case 61 can be extended by a certain length while returning to a position before being pressed by the engagement of the stopper 691, the slide bar 692, and the first spring 693.

Please refer to fig. 4, the fixing assembly 4 includes threaded posts 43 respectively and fixedly installed on the upper end of the limiting panel 3, the upper end of the threaded posts 43 is connected with a rotating handle 44 through threads, the support rods 41 are slidably disposed on the axial side walls of the two threaded posts 43, one ends of the two support rods 41 are connected with the first arc-shaped plate 42 together, the upper end of the workbench 1 is fixedly installed with a second arc-shaped plate 46, the second arc-shaped plate 46 is located under the first arc-shaped plate 42, the threaded posts 43 are sleeved with third springs 45, and by means of the third springs 45, the support rods 41 corresponding to the positions are supported, two ends of the third springs 45 are respectively connected with the side walls of the support rods 41 and the upper end of the limiting panel 3. Under the cooperation of the supporting rod 41, the first arc-shaped plate 42, the threaded column 43, the third spring 45 and the second arc-shaped plate 46, the necks of the experimental rats with different sizes can be limited.

Referring to fig. 5-6, the fixing panel 2 is provided with an anti-bite assembly 5.

The anti-biting assembly 5 comprises a first limiting plate 51 and a second limiting plate 54 which are respectively fixedly installed on the fixed panel 2, a clamping plate 53 is arranged on the first limiting plate 51 in a sliding mode, connecting holes 52 are formed in the clamping plate 53 and the second limiting plate 54, and a buffering assembly 55 is arranged on the first limiting plate 51. The laboratory mouse is prevented from biting the own tongue by the cooperation of the second restriction plate 54, the clamp plate 53 and the coupling hole 52.

Buffering subassembly 55 includes symmetrical fixed mounting slide bar 553 on first limiting plate 51, and mounting groove 551 has been seted up to the symmetry on the first limiting plate 51, and two slide bar 553 fixed mounting are in the mounting groove 551 that corresponds the position, and splint 53 slides and sets up on the slide bar 553 that corresponds the position, all cup jointed second spring 552 on two slide bar 553, the both ends of two second springs 552 respectively with the mounting groove 551 diapire that corresponds the position, splint 53's lateral wall fixed connection. The sliding rod 553 and the second spring 552 cooperate to allow a certain space for the laboratory mouse to move.

The working principle is as follows: at first, place laboratory mouse's neck on second arc 46, the operator rotates two rotatory handles 44 afterwards, two rotatory handles 44 take place the displacement at the screw thread post 43 that corresponds the position, constantly push down through two rotatory handles 44, two bracing pieces 41 can drive first arc 42 and be close to second arc 46 motion gradually, two bracing pieces 41 can play certain support to third spring 45 simultaneously, can fix laboratory mouse's health middle part through first arc 42 and second arc 46's cooperation, it struggles to reach to take place when preventing laboratory mouse from reviving.

Then, the operator opens the laboratory mouse to place the second limiting plate 54 and the clamping plate 53 in the mouth of the laboratory mouse, and the teeth of the laboratory mouse are sleeved in the corresponding connecting holes 52, when the laboratory mouse wakes up the mouth to bite, the clamping plate 53 slides on the sliding rod 553 in the corresponding position, and meanwhile, the clamping plate 53 extrudes the second spring 552 to prevent the laboratory mouse from biting the tongue, so that the mouth of the laboratory mouse has a certain buffering effect.

Finally, the operator presses connection cartridge case 61 and moves, connection cartridge case 61 drives connecting rod 62 and moves together, connection cartridge case 61 slides on the slide bar 692 that corresponds the position, the one end of connecting cartridge case 61 extrudes first spring 693 simultaneously, connect cartridge case 61 simultaneously and can keep away from spacing panel 3 motion until the ear that is close to the laboratory mouse moves, the duct of laboratory mouse can be entered into to the elasticity hemisphere 66 that serves as connection cartridge case 61, strut the duct of laboratory mouse through two elasticity hemispheres 66, after that through rotating connecting rod 62, connecting rod 62 drives ball 64 and moves about in arc recess 63, ball 64 drives probe 65 and imaging element 67 and carries out the rotation of small amplitude at the duct of laboratory mouse, can reach and detect the formation of image to it under the prerequisite of not injuring the laboratory mouse ear, and is simple in operation, high durability and convenient use.

Those not described in detail in this specification are well within the skill of the art.

Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.

Claims (5)

1. A brain stereotaxic apparatus for tracing a neural loop comprises a workbench (1) and a fixed panel (2) fixedly arranged at the upper end of the workbench (1),

it is characterized by also comprising:

the limiting panels (3) are symmetrically and fixedly arranged at the upper end of the workbench (1), the upper ends of the two limiting panels (3) are provided with fixing components (4) for limiting the laboratory mouse together, and ear detection components (6) are arranged on the two limiting panels (3);

ear detection subassembly (6) set up connection shell (61) on spacing panel (3) including sliding, movable pore (68) have been seted up on connection shell (61), it is provided with connecting rod (62) to alternate in movable pore (68), the intercommunication has arc recess (63) on the lateral wall of movable pore (68), arc recess (63) internalization is provided with ball (64), the lower extreme fixed mounting of ball (64) has probe rod (65), the one end of probe rod (65) is provided with imaging element (67), be provided with coupling unit (69) on spacing panel (3), the elastic hemisphere (66) of one end symmetry fixed mounting of connection shell (61).

2. The neural circuit tracking brain stereotaxic apparatus according to claim 1, wherein: connecting element (69) are including stopper (691) of symmetry fixed mounting on spacing panel (3) inner chamber lateral wall, two the equal fixed mounting in upper end of stopper (691) has slide bar (692), the both ends of connecting cartridge case (61) all slide and set up on slide bar (692) of corresponding position, two first spring (693) has all been cup jointed on slide bar (692), the both ends of first spring (693) respectively with the lateral wall of stopper (691), the lateral wall fixed connection of connecting cartridge case (61).

3. The neural circuit tracking brain stereotaxic apparatus according to claim 2, wherein: fixed subassembly (4) are including installing screw thread post (43) in spacing panel (3) upper end admittedly respectively, the upper end threaded connection of screw thread post (43) has rotatory handle (44), two equal slip on the axial lateral wall of screw thread post (43) is provided with bracing piece (41), two the one end of bracing piece (41) is connected with first arc (42) jointly, the upper end fixed mounting of workstation (1) has second arc (46), second arc (46) are located first arc (42) under, third spring (45) have been cup jointed on screw thread post (43), the both ends of third spring (45) respectively with the lateral wall of bracing piece (41), the upper end fixed connection of spacing panel (3).

4. A neural circuit tracking brain stereotaxic apparatus according to claim 3, wherein: the fixed panel (2) is provided with an anti-biting component (5);

prevent that interlock subassembly (5) is including first limiting plate (51) and second limiting plate (54) of difference fixed mounting on fixed panel (2), slip on first limiting plate (51) and be provided with splint (53), connecting hole (52) have all been seted up on splint (53) and second limiting plate (54), be provided with buffering subassembly (55) on first limiting plate (51).

5. The neural circuit tracking brain stereotaxic apparatus according to claim 4, wherein: buffer unit (55) including symmetry fixed mounting slide bar (553) on first limiting plate (51), mounting groove (551) have been seted up to the symmetry on first limiting plate (51), two slide bar (553) fixed mounting is in mounting groove (551) of corresponding position, splint (53) slide to be set up on slide bar (553) of corresponding position, two all cup joint second spring (552) on slide bar (553), two the both ends of second spring (552) respectively with mounting groove (551) diapire, the lateral wall fixed connection of splint (53) of corresponding position.

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