CN218567019U - Gas source device and in-vitro diagnostic instrument - Google Patents
Gas source device and in-vitro diagnostic instrument Download PDFInfo
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- CN218567019U CN218567019U CN202220304861.9U CN202220304861U CN218567019U CN 218567019 U CN218567019 U CN 218567019U CN 202220304861 U CN202220304861 U CN 202220304861U CN 218567019 U CN218567019 U CN 218567019U
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Abstract
The utility model discloses an air supply device, include: the tank body is provided with a first cavity and a second cavity which are independently arranged; and a gas circuit system, the gas circuit system comprising: the main gas path is communicated with the first cavity and the external gas generating device, and the second cavity and the external gas generating device and is used for pressurization; the gas distribution channel is used for communicating the first cavity with the second cavity; and the one-way speed regulating valve is arranged on the gas distribution path and is used for controlling the on-off of the gas distribution path between the first cavity and the second cavity. In the technical scheme that this air supply unit provided, this first chamber carries out the rapid pressurization through main gas circuit external air feeder, and, this first chamber carries out the pressure supplementation through dividing gas circuit intercommunication second chamber to make this first chamber can pressurize fast to predetermined constant voltage state, and can be in dynamic constant voltage state for a long time, improve the constant voltage stability in first chamber. Therefore, the air source device has the characteristics of simple air path structure and good constant pressure performance.
Description
Technical Field
The utility model belongs to the technical field of medical instrument, especially an air supply device and external diagnostic equipment.
Background
In the field of in vitro diagnostic tests, blood clotting in the heart or blood vessels of a living subject can lead to thrombosis and thrombotic disease, and it is therefore necessary to periodically test the patient's blood for thrombosis. The thromboelastogram is a general instrument for detecting blood coagulation and thrombus formation, and can monitor the coagulation process from the whole dynamic process of platelet aggregation, coagulation, fibrinolysis and the like, and monitor and analyze the coagulation state of a blood sample. The final result of the coagulation process is the formation of a blood clot, and the physical properties of the blood clot, such as the strength and stability of the blood clot, determine whether the blood clot has normal coagulation function. At present, a novel detection method of a thromboelastogram apparatus appears, in which a constant pressure is applied to a blood sample, for example, the constant pressure is applied at intervals, and as the blood sample gradually coagulates from a liquid state to a solid state in a sample placement area, the pressure applied during the phase transition of the blood sample gradually decreases, so that a detection curve can be obtained by converting the change trend of the pressure in the sample placement area along with time according to the change condition of an output pressure signal, and the detection curve can represent the phase transition process of the blood sample. However, in the detection method of the thrombelastogram apparatus, since a constant pressure needs to be applied to the blood sample, and the constant pressure is far less than the atmospheric pressure, in the prior art, it is difficult to ensure that the constant pressure is continuously input to the sample placement area, which affects the detection accuracy.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an air supply unit and external diagnostic instrument for improve prior art through place the district to blood sample and let in the method of constant pressure in order to obtain blood sample phase transition process through the pressure variation trend, difficult assurance is continuously placed the district to the sample and is inputed invariable pressure, leads to influencing the shortcoming that detects the accuracy nature.
The technical scheme is as follows:
an air source device, which comprises a tank body and an air path system,
the tank body is provided with a first cavity and a second cavity which are independently arranged;
the gas path system comprises a main gas path, a gas distribution path and a one-way speed regulating valve,
the main air path is communicated with the first cavity and the external gas generating device, and the second cavity and the external gas generating device and is used for pressurization;
the gas distribution channel is used for communicating the first cavity and the second cavity;
the one-way speed regulating valve is arranged on the gas distribution path and used for controlling the on-off of the gas distribution path between the first cavity and the second cavity.
In one embodiment, the air path system further comprises a first pressure relief air path, a first switch valve and a first speed regulating valve,
the first switch valve is used for connecting the first cavity and the first pressure relief air path;
the first speed regulating valve is arranged on the first pressure relief air circuit and used for regulating the flow rate of the first pressure relief air circuit.
In one embodiment, the air path system further comprises a second pressure relief air path, a second switch valve and a second speed regulating valve,
the second switch valve is used for connecting the second cavity and the second pressure relief air path;
the second speed regulating valve is arranged on the second pressure relief air circuit and used for regulating the flow rate of the second pressure relief air circuit.
In one embodiment, the air path system further comprises a third pressure relief air path and a third on-off valve,
the third pressure relief air path is communicated with the first cavity;
the third switch valve is arranged on the third pressure relief air path and used for controlling the third pressure relief air path to be communicated with or disconnected from the first cavity.
In one embodiment, the air path system further comprises a fourth pressure relief air path and a fourth switch valve,
the fourth pressure relief air path is communicated with the second cavity;
and the fourth switch valve is arranged on the fourth pressure relief gas circuit and is used for controlling the fourth pressure relief gas circuit to be communicated with or disconnected from the second cavity.
In one embodiment, the gas circuit system further comprises a first pressure sensor and a fifth switch valve, wherein the first pressure sensor is communicated with the first cavity through the fifth switch valve; and/or the presence of a gas in the atmosphere,
the gas path system also comprises a second pressure sensor and a sixth switching valve, wherein the second pressure sensor is communicated with the second cavity through the sixth switching valve.
In one embodiment, the can body has a first open end and a second open end, the first open end is in communication with the first chamber, and the second open end is in communication with the second chamber;
the gas source device also comprises a first end cover and a second end cover, wherein the first end cover is used for sealing the first opening end; the second end cap is for sealing the second open end.
In one embodiment, the gas source device further comprises a first sealing element, a first annular groove matched with the first open end is formed in the first end cover, the first open end is inserted into the first annular groove, and the first sealing element is arranged between the first open end and the first annular groove; and/or the presence of a gas in the gas,
the air source device further comprises a second sealing element, a second annular groove matched with the second opening end is formed in the second end, the second opening end is inserted into the second annular groove, and the second sealing element is arranged between the second opening end and the second annular groove.
In one embodiment, the tank body comprises side enclosing plates, a partition plate, a bottom plate and a top plate,
the first end cover and the second end cover of the side enclosing plate are arranged on the bottom plate;
the top plate cover is arranged at the tops of the side coamings, the first end cover and the second end cover;
a cavity is defined among the top plate, the side enclosing plates, the first end cover, the second end cover and the bottom plate, and the partition plate is inserted into the cavity to divide the cavity into the first cavity and the second cavity.
Based on the same purpose, the utility model also provides an in-vitro diagnostic apparatus, which comprises a reagent card and the gas source device,
the reagent card is provided with at least one flow passage; the first cavity is communicated with the flow passage through an air inlet pipeline.
The utility model provides a technical scheme has following advantage and effect:
the tank body of the air source device is provided with a first cavity and a second cavity, wherein the second cavity of the tank body can be filled with pressure higher than that of the first cavity of the tank body, the first cavity of the tank body is a constant pressure cavity, so that the first cavity of the tank body is always kept in a constant pressure state in a working state, and the constant pressure can be applied to a blood sample through the first cavity to detect the phase change process of the blood sample. Wherein this first chamber carries out rapid pressurization through main gas circuit external air feeder, and, this first chamber carries out the moisturizing through dividing gas circuit intercommunication second chamber to make this first chamber can pressurize fast to predetermined constant voltage state, and can be in dynamic constant voltage state for a long time, improve the constant voltage stability in first chamber. Therefore, the air source device has the characteristics of simple air path structure and good constant pressure performance.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and, together with the description, serve to explain the principles, principles and effects of the invention.
Unless otherwise specified or defined, the same reference numerals in different figures refer to the same or similar features, and different reference numerals may be used for the same or similar features.
Fig. 1 is a schematic perspective view of an air supply device according to an embodiment of the present invention;
fig. 2 is an exploded schematic view of an air supply device according to an embodiment of the present invention;
fig. 3 is a schematic longitudinal sectional structure view of a tank body according to an embodiment of the present invention;
fig. 4 is a schematic view of a connection structure of the gas circuit system according to the embodiment of the present invention;
FIG. 5 is a schematic diagram of the external diagnostic apparatus in an assembled state with respect to the gas supply device;
FIG. 6 is a schematic front view of a reagent card;
FIG. 7 is a schematic view of the back side of the reagent card;
fig. 8 is an exploded view of the reagent card.
Description of the reference numerals:
100. an in vitro diagnostic instrument;
4. an air supply device; 41. a tank body; 411. a first chamber; 4111. a base plate; 4112. a top plate; 4113. side coaming plates; 4114. a partition plate; 412. a second chamber; 413. a first open end; 414. a second open end; 415. a first end cap; 4151. a first annular groove; 416. a second end cap; 417. a first seal member; 418. a second seal member; 42. a gas path system; 421. a main gas path; 422. gas path distribution; 423. a one-way speed regulating valve; 424. a first pressure relief air passage; 425. a first on-off valve; 426. a first speed regulating valve; 427. a second pressure relief air passage; 428. a second on-off valve; 429. a second speed regulating valve; 431. a third pressure relief air path; 432. a third on-off valve; 433. a fourth pressure relief air passage; 434. a fourth switching valve; 435. a first pressure sensor; 436. a fifth on-off valve; 437. a second pressure sensor; 438. and a sixth switching valve.
200. A reagent card; 220. a flow channel; 240. and covering the film layer.
Detailed Description
In order to facilitate an understanding of the invention, specific embodiments thereof will be described in more detail below with reference to the accompanying drawings.
Unless specifically stated or otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In the case of combining the technical solution of the present invention with realistic scenarios, all technical and scientific terms used herein may also have meanings corresponding to the objects of realizing the technical solution of the present invention.
As used herein, unless otherwise specified or defined, "first, \ 8230," is used merely to distinguish between names, and does not denote a particular quantity or order.
As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items, unless otherwise specified or defined.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly secured to the other element or intervening elements may also be present; when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present; when an element is referred to as being "mounted on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "on" another element, it can be directly on the other element or intervening elements may also be present.
It should be noted that the gas source device 4 can be used as a gas source output device, and has an independent control system for controlling the gas source output, for example, the gas source device 4 can be applied to the in-vitro diagnostic apparatus 100 for detecting the process of liquid phase change, the process of detecting liquid phase change can be a process of detecting the solidification of the sample from liquid to solid, and can further detect the process of melting the solidified solid again to liquid, and the gas source device 4 is used for providing a constant gas source for the sample placement area of the in-vitro diagnostic apparatus 100. In the embodiment, the gas source device 4 is suitable for use in a detection device of a thromboelastography instrument, and the gas source device 4 can be used for applying a constant pressure to a blood sample.
The utility model provides an air supply unit 4, as shown in fig. 1 to 4, air supply unit 4 includes jar body 41, and jar body 41 has independent setting's first chamber 411 and second chamber 412. The gas path system 42 comprises a main gas path 421, a branch gas path 422 and a one-way speed regulating valve 423; the main gas path 421 is used for communicating the first chamber 411 with an external gas generating device and for communicating the second chamber 412 with the external gas generating device, so that gas can be introduced through the external gas generating device of the main gas path 421 to pressurize the first chamber 411 and the second chamber 412. The air distribution passage 422 is used for communicating the first cavity 411 and the second cavity 412; the one-way speed regulating valve 423 is arranged on the gas distribution path 422 and is used for controlling the on-off of the gas distribution path 422 between the first chamber 411 and the second chamber 412. Specifically, in this embodiment, the pressure in the second cavity 412 of the tank 41 is higher than the pressure in the first cavity 411 of the tank 41, and the pressure in the first cavity 411 of the tank 41 is a constant pressure cavity; it should be noted that the first chamber 411 forming a constant pressure chamber means that the pressure output value in the first chamber 411 is kept substantially constant, but small fluctuation of the output value is allowed within the error tolerance range of the instrument, specifically, the pressure values in the first chamber 411 and the second chamber 412 can be set within the range (< 4500 PA) in a self-defined manner, in one embodiment, the pressure value in the second chamber 412 is 2600PA, and the pressure value in the first chamber 411 is (1300 ± 10 PA).
It can be understood that, when the air source device 4 is used in a detection device of a thromboelastogram apparatus, the second chamber 412 can supply air into the first chamber 411 through the control of the air distribution path 422, and can apply a constant pressure to a blood sample through the first chamber 411 to perform detection of a phase transition process of the blood sample, wherein the first chamber 411 and the second chamber 412 can be respectively externally connected with the air supply device through a main air path 421, when the air source device 4 is just started to perform an initial air intake process, the first chamber 411 and the second chamber 412 can be rapidly pressurized to an air pressure range near a preset value through the main air path 421 in advance, and then the air distribution path 422 is controlled to open through the one-way speed control valve 423, the second chamber 412 supplies air and supplements pressure to the first chamber 411 through the air distribution path 422 to maintain a dynamic constant pressure state in the first chamber 411, and the second chamber 412 supplements pressure through the main air path 421. So, first chamber 411 can carry out pressurization fast through the external air feeder of main gas circuit 421, and, this first chamber 411 carries out the pressure supplementing through gas circuit 422 intercommunication second chamber 412 to make this first chamber 411 can pressurize fast to predetermined constant voltage state, and can be in dynamic constant voltage state for a long time, improve first chamber 411's constant voltage stability.
In summary, the canister 41 of the air source device 4 has a first cavity 411 and a second cavity 412, wherein the second cavity 412 of the canister 41 can be filled with a pressure higher than the first cavity 411 of the canister 41, the first cavity 411 of the canister 41 is a constant pressure cavity, so that the first cavity 411 of the canister 41 is always kept in a constant pressure state in a working state, and the first cavity 411 can apply a constant pressure to the blood sample to perform the detection of the phase transition process of the blood sample. Wherein this first chamber 411 carries out pressurization fast through the external air feeder of main gas circuit 421, and, this first chamber 411 carries out the pressure supplementation through gas circuit 422 intercommunication second chamber 412 to make this first chamber 411 can pressurize fast to predetermined constant voltage state, and can be in dynamic constant voltage state for a long time, improve the constant voltage stability of first chamber 411. Therefore, the air source device 4 has the characteristics of simple air path structure and good constant pressure performance.
In some embodiments, as shown in FIG. 2, canister 41 has a first open end 413 and a second open end 414, first open end 413 being disposed in communication with first chamber 411, and second open end 414 being disposed in communication with second chamber 412; the gas supply means 4 further comprises a first end cap 415 and a second end cap 416; a first end cap 415 is used to seal the first open end 413 and a second end cap 416 is used to seal the second open end 414. As can be understood, the first end cap 415 and the second end cap 416 are matched with each other, so that the first sealed cavity 411 and the second sealed cavity 412 can be formed, and the non-integrated sealing structure of the tank 41 can facilitate the assembly of the components of the air source device 4, reduce the assembly difficulty, and facilitate the disassembly, assembly and maintenance. Of course, in other embodiments, the tank 41 may also be an integrated sealing structure, and is not limited herein.
In some embodiments, can 41 comprises a floor 4111, a roof 4112, side walls 4113, and a partition 4114; the bottom ends of the side wall plate 4113, the first end cover 415 and the second end cover 416 are arranged on the bottom plate 4111, the top end covers of the side wall plate 4113, the first end cover 415 and the second end cover 416 are provided with a top plate 4112, a cavity is defined between the top plate 4112, the side wall plate 4113, the first end cover 415, the second end cover 416 and the bottom plate 4111, and a partition plate 4114 is inserted into the cavity to separate the cavity into a first cavity 411 and a second cavity 412. Specifically, in this embodiment, the side wall plate 4113 includes a first side plate and a second side plate, where the first side plate and the second side plate are disposed opposite to each other, so that the top plate 4112, the first side plate, the second side plate, the bottom plate 4111, the first end cap 415, and the second end cap 416 cooperate to form the cavity. Of course, the above is only one of the ways of disposing the side wall 4113, and in practical applications, the side wall may be disposed separately according to specific situations. In the present embodiment, the can body 41 is a rectangular body to form a regular can container structure. It can be understood that the first cavity 411 and the second cavity 412 with good sealing performance can be formed by the cooperation of the top plate 4112, the side wall plate 4113, the first end cover 415, the second end cover 416, the bottom plate 4111 and the partition plate 4114 for packaging, and the assembling and the installation operations of various components are facilitated. It should be further noted that the top plate 4112, the bottom plate 4111, the side wall plate 4113 and the partition plate 4114 may be an integrally formed structure or a separately assembled structure, and are not limited herein.
Specifically, in this embodiment, the partition 4114 is vertically inserted into the cavity, and two ends of the can 41 opposite to the partition 4114 form a first opening end 413 and a second opening end 414, respectively. It is understood that the side of the partition 4114 facing the first end cap 415, together with the side wall plate 4113, the top plate 4112 and the bottom plate 4111, forms a first cavity 411; towards one side of second end cover 416 in baffle 4114, enclose with side wall plate 4113, roof 4112 and bottom plate 4111 jointly and establish and form second chamber 412, be convenient for correspond the position setting of first chamber 411 at roof 4112 and side wall plate 4113 and correspond the position assembly of second chamber 412 and correspond the part that the chamber corresponds to use separately, be convenient for operating personnel's use and observation.
In some embodiments, as shown in fig. 3, the volume of the first chamber 411 is larger than the volume of the second chamber 412, and the first chamber 411 of the tank 41 can be replenished with pressure through the second chamber 412, so that the first chamber 411 of the tank 41 can always maintain a constant pressure state in the working state. It can be understood that, by setting the volume of the first chamber 411 of the tank 41 to be larger than that of the second chamber 412, the first chamber 411 of the tank 41 can be supplemented with pressure through the second chamber 412, and the first chamber 411 has a larger space buffer pressure, so that the fluctuation in the process of air inlet and outlet in the first chamber 411 is small, and a stable constant pressure state is formed.
In some embodiments, as shown in fig. 3, the ratio of the volume of the first chamber 411 to the volume of the second chamber 412 is in a range of 2 to 4, and specifically, the ratio of the volume of the first chamber 411 to the volume of the second chamber 412 may be in a range of 2. It can be understood that the volume ratio of the first chamber 411 to the second chamber 412 can ensure that the first chamber 411 is at a better constant pressure stability within this range, and can be quickly adjusted to a preset pressure value when the first chamber 411 is at a pressure value lower or higher than the preset pressure value, so as to reduce the pressure fluctuation of the first chamber 411.
In some embodiments, as shown in fig. 2, the air supply device 4 further includes a first sealing member 417, the first end cap 415 defines a first annular groove 4151 adapted to the first open end 413, the first open end 413 is inserted into the first annular groove 4151, and the first sealing member 417 is disposed between the first open end 413 and the first annular groove 4151; and/or, the gas source device 4 further includes a second sealing member 418, the second end cap 416 is provided with a second annular groove adapted to the second open end 414, the second open end 414 is inserted into the second annular groove, and the second sealing member 418 is disposed between the second open end 414 and the second annular groove. It can be understood that the first open end 413 of the tank 41 is connected to the first annular groove 4151 of the first end cap 415 in a sealing manner through the first sealing member 417, and the second open end 414 is connected to the second annular groove of the second end cap 416 in a sealing manner through the second sealing member 418, so that the distance between the first end cap 415 and the second end cap 416 and the tank 41 can be controlled by size, the compression range of the first sealing member 417 and the second sealing member 418 can be effectively ensured to be about 20%, the assembly difficulty can be effectively reduced, and good air tightness can be ensured.
In some embodiments, the canister 41 is a plastic canister. In this embodiment, the tank 41 may be made of plastic materials such as polyoxymethylene resin and polyamide fiber, and the influence of the ambient temperature on the pressure values in the first chamber 411 and the second chamber 412 of the tank 41 can be effectively avoided.
In some embodiments, as shown in fig. 4, pneumatic circuit system 42 further includes a first pressure relief pneumatic circuit 424, a first switching valve 425, and a first speed valve 426; wherein the first switching valve 425 is used for connecting the first cavity 411 and the first pressure relief air passage 424; a first speed valve 426 is provided on the first pressure relief air path 424 for adjusting a flow rate of the first pressure relief air path 424. It can be understood that, when the pressure in the first chamber 411 exceeds the preset range, the first switch valve 425 may be opened at this time, so that the pressure in the first chamber 411 is discharged through the first pressure relief air channel 424, and the flow rate of the first pressure relief air channel 424 is adjusted through the first speed regulating valve 426, so as to implement slow pressure relief in the first chamber 411, and ensure a dynamic constant pressure state in the first chamber 411.
In some embodiments, as shown in fig. 4, the air circuit system 42 further includes a second pressure relief air circuit 427, a second switch valve 428, and a second speed valve 429; the second switch valve 428 is used for connecting the second chamber 412 with the second pressure relief air passage 427; a second speed valve 429 is provided on the second pressure relief air path 427 for adjusting the flow rate of the second pressure relief air path 427. It can be understood that, when the pressure in the second chamber 412 exceeds the preset range, the second on-off valve 428 may be opened to discharge the pressure in the second chamber 412 through the second pressure relief air path 427, and the flow rate of the second pressure relief air path 427 is adjusted through the second speed regulating valve 429, so as to realize slow pressure relief in the second chamber 412, reduce the flow rate of the make-up air in the second chamber 412, and further ensure the pressure fluctuation in the first chamber 411; therefore, through the mutual cooperation of first speed control valve 426 and second speed control valve 429, can effectively guarantee the constant voltage stability in first chamber 411, effectively guarantee that can be in dynamic constant voltage state for a long time in first chamber 411.
In some embodiments, as shown in fig. 4, air path system 42 further includes a third pressure relief air path 431 and a third on/off valve 432, where third pressure relief air path 431 is communicated with first cavity 411; the third switching valve 432 is disposed on the third pressure relief air passage 431, and is used for controlling the third pressure relief air passage 431 to be connected to or disconnected from the first chamber 411. It can be understood that after the air supply device 4 completes air supply, the third on/off valve 432 can control the third pressure relief air channel 431 to communicate with the first cavity 411, so as to achieve rapid pressure relief in the first cavity 411. And/or, the air path system 42 further includes a fourth pressure relief air path 433 and a fourth switch valve 434, where the fourth pressure relief air path 433 is communicated with the second chamber 412; the fourth switching valve 434 is disposed on the fourth pressure relief air passage 433 and is configured to control the fourth pressure relief air passage 433 to be communicated with or disconnected from the second chamber 412; it can be understood that after the air supply device 4 completes supplying air, the fourth switch valve 434 can control the fourth pressure relief air path 433 to communicate with the second chamber 412, so as to achieve rapid pressure relief in the second chamber 412.
In some embodiments, as shown in fig. 4, the air path system 42 further includes a first pressure sensor 435 and a fifth switch valve 436, and the first pressure sensor 435 is controlled to communicate with the first chamber 411 through the fifth switch valve 436. It is understood that the first pressure sensor 435 can be enabled to achieve the calibration of the air in the first chamber 411 by controlling the first pressure sensor 435 to communicate with the first chamber 411 through the fifth switch valve 436, and the fifth switch valve 436 is in a normally closed state. And/or, the air passage system 42 further includes a second pressure sensor 437 and a sixth switching valve 438, wherein the second pressure sensor 437 is controlled to communicate with the second chamber 412 by the sixth switching valve 438; it can be understood that the second pressure sensor 437 can be enabled to perform the blank calibration in the second chamber 412 by controlling the second pressure sensor 437 to communicate with the second chamber 412 by the sixth switching valve 438, which is in a normally closed state 438, wherein the fifth switching valve 436 and the sixth switching valve 438 can be solenoid valves. Therefore, the first pressure sensor 435 and the second pressure sensor 437 are matched with each other, so that the first chamber 411 and the second chamber 412 can be corrected to be empty, and the consistency of the initial states of the first chamber 411 and the second chamber 412 is ensured.
In some embodiments, the air supply device 4 further includes a circuit board disposed on the tank 41, and the circuit board is used for controlling the operation of the air path system 42 so as to maintain the pressure state in the first chamber 411 and the second chamber 412 within a preset range. In addition, this air supply unit 4 still includes the absolute pressure sensor that sets up on the circuit board, and this absolute pressure sensor is used for sensing the altitude and the ambient temperature that this air supply unit 4 is located, can make this air supply unit 4 carry out the air correction to first chamber 411 and second chamber 412 automatically according to the position that self is located, further guarantees the uniformity of first chamber 411 and the initial condition of second chamber 412.
The utility model discloses still provide an external diagnostic apparatus 100, as shown in fig. 1 to fig. 8, external diagnostic apparatus 100 includes reagent card 200 and as above air supply unit 4, and reagent card 200 has at least one runner 220, and first chamber 411 circulates through inlet duct and reagent card 200's runner 220. It should be noted that the reagent card 200 mentioned in the present embodiment has a covering film layer 240, the reagent card 200 is provided with a flow channel 220, and the like, the covering film layer 240 is disposed on the reagent card 200 and covers the flow channel 220, and the like; it should be further noted that the flow passages 220 of the reagent card 200 are formed by the cooperation of the hole passages formed on the front surface and the hole passages formed on the back surface of the reagent card 200 to form the flow passages 220 of the reagent card 200.
It can be understood that, the in vitro diagnostic apparatus 100 applies air to the flow channels 220 of the reagent card 200 through the air supply device 4 to apply a constant pressure to the flow channels 220 of the reagent card 200, and the process of air supply and air exhaust is periodically repeated, the reagent card 200 has a pressure sensor at the position detected by the flow channels 220, the pressure sensor records the pressure data of the reagent card 200, and as the blood sample undergoes fibrinolysis, the blood elasticity changes, and the detected pressure value also changes. The data collected by the pressure sensor is processed by hardware and software to generate a corresponding graph, and a corresponding thrombus elastogram graph of the detected blood sample is formed.
In summary, the extracorporeal diagnostic apparatus 100 is provided with the air source device 4, the tank 41 of the air source device 4 has the first chamber 411 and the second chamber 412, wherein the second chamber 412 of the tank 41 can be filled with a pressure higher than the first chamber 411 of the tank 41, and the first chamber 411 of the tank 41 is a constant pressure chamber, so that the first chamber 411 of the tank 41 is always kept in a constant pressure state in a working state, and the first chamber 411 can apply a constant pressure to the blood sample to perform the detection of the phase transition process of the blood sample. Wherein this first chamber 411 carries out pressurization fast through the external air feeder of main gas circuit 421, and, this first chamber 411 carries out the pressure supplementation through gas circuit 422 intercommunication second chamber 412 to make this first chamber 411 can pressurize fast to predetermined constant voltage state, and can be in dynamic constant voltage state for a long time, improve the constant voltage stability of first chamber 411. Therefore, the air source device 4 has the characteristics of simple air path structure and good constant pressure performance.
When the drawing description is quoted, the new characteristics are explained; in order to avoid that repeated reference to the drawings causes the description to be not concise, the drawings are not referred to one by one in the case of clear description of the described features.
The above embodiments are intended to be illustrative, and should not be construed as limiting the scope of the invention, and the technical solutions, objects and effects of the present invention are described in full herein.
The above examples are not intended to be exhaustive list of the present invention, and there may be many other embodiments not listed. Any replacement and improvement made on the basis of not violating the conception of the utility model belong to the protection scope of the utility model.
Claims (10)
1. Air supply means, characterized in that said air supply means comprises:
the tank body is provided with a first cavity and a second cavity which are independently arranged; and
the gas circuit system, the gas circuit system includes:
the main gas path is communicated with the first cavity and the external gas generating device, and the second cavity and the external gas generating device and is used for pressurization;
the gas distribution path is used for communicating the first cavity with the second cavity; and
and the one-way speed regulating valve is arranged on the gas distribution path and is used for controlling the on-off of the gas distribution path between the first cavity and the second cavity.
2. The gas source apparatus of claim 1, wherein the gas circuit system further comprises:
a first pressure relief air passage;
the first switch valve is used for connecting the first cavity and the first pressure relief air path; and
and the first speed regulating valve is arranged on the first pressure relief air path and is used for regulating the flow rate of the first pressure relief air path.
3. The air supply device according to claim 1, wherein said air circuit system further comprises:
a second pressure relief air passage;
the second switch valve is used for connecting the second cavity and the second pressure relief air passage; and
and the second speed regulating valve is arranged on the second pressure relief air circuit and is used for regulating the flow rate of the second pressure relief air circuit.
4. The air supply device according to claim 1, wherein said air circuit system further comprises:
the third pressure relief air passage is communicated with the first cavity; and
and the third switch valve is arranged on the third pressure relief air circuit and used for controlling the third pressure relief air circuit to be communicated with or disconnected from the first cavity.
5. The air supply device according to claim 1, wherein said air circuit system further comprises:
a fourth pressure relief air passage communicated with the second chamber; and
and the fourth switching valve is arranged on the fourth pressure relief air path and used for controlling the fourth pressure relief air path to be communicated with or disconnected from the second cavity.
6. The air supply arrangement as defined in claim 1, wherein said air circuit system further includes a first pressure sensor and a fifth switching valve, said first pressure sensor being in communication with said first chamber through said fifth switching valve; and/or the presence of a gas in the atmosphere,
the gas path system also comprises a second pressure sensor and a sixth switching valve, wherein the second pressure sensor is communicated with the second cavity through the sixth switching valve.
7. The air supply assembly according to any one of claims 1 to 6 wherein said canister body has a first open end and a second open end, said first open end being disposed in communication with said first chamber and said second open end being disposed in communication with said second chamber;
the gas source device further comprises:
a first end cap for sealing the first open end; and
a second end cap for sealing the second open end.
8. The air supply assembly as defined in claim 7, further comprising a first sealing member, wherein said first end cap defines a first annular groove adapted to said first open end, said first open end is received in said first annular groove, and said first sealing member is disposed between said first open end and said first annular groove; and/or the presence of a gas in the gas,
the air source device further comprises a second sealing element, a second annular groove matched with the second opening end is formed in the second end, the second opening end is inserted into the second annular groove, and the second sealing element is arranged between the second opening end and the second annular groove.
9. The air supply assembly as defined in claim 7, wherein said canister body includes:
side coaming plates;
a partition plate;
the side enclosing plates, the first end cover and the second end cover are all arranged on the bottom plate; and
the top plate covers the top parts of the side coamings, the first end cover and the second end cover;
a cavity is defined among the top plate, the side enclosing plates, the first end cover, the second end cover and the bottom plate, and the partition plate is inserted into the cavity to divide the cavity into the first cavity and the second cavity.
10. An in vitro diagnostic apparatus, characterized in that it comprises:
a reagent card having at least one flow channel; and
an air supply assembly as claimed in any one of claims 1 to 9 wherein said first chamber is in communication with said flow passage via an air inlet conduit.
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CN114487455A (en) * | 2022-02-14 | 2022-05-13 | 广州万孚生物技术股份有限公司 | In-vitro diagnostic instrument and control method thereof |
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Cited By (1)
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CN114487455A (en) * | 2022-02-14 | 2022-05-13 | 广州万孚生物技术股份有限公司 | In-vitro diagnostic instrument and control method thereof |
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