CN218298396U

CN218298396U - Artificial cochlea simulation rapid integration test system

Info

Publication number: CN218298396U
Application number: CN202221730736.0U
Authority: CN
Inventors: 付寅飞; 黄穗; 李亚杰; 朱东奇; 袁杭青
Original assignee: Zhejiang Nurotron Biotechnology Co ltd
Current assignee: Zhejiang Nurotron Biotechnology Co ltd
Priority date: 2022-07-05
Filing date: 2022-07-05
Publication date: 2023-01-13
Anticipated expiration: 2032-07-05

Abstract

The utility model discloses a test system is integrated fast in artifical cochlea simulation, including installing the host computer of the test system software of integrating fast, integrating tester, salinity tester, debugging box, synchronizing signal line, speech treater, implant, electrode line, serial port line. The upper computer is configured with an integration tester for collecting parameters, generating stimulation and sending, receiving collected data, and calculating the saline impedance, the implant electrode impedance, the amplitude symmetry ratio and the charge symmetry ratio of electrode stimulation signals; the integration tester receives the synchronous signal, transmits, collects and amplifies data; a salinity tester tests the saline concentration of the implant; the debugging box converts the instruction that the host computer sent into speech processor acceptable signal, conveys the synchronizing signal to the integration tester through the synchronizing signal line simultaneously. The utility model discloses reduce the amazing unusual risk of artifical cochlea electrode, can realize implanting the preceding investigation, the clinical study after also being convenient for implant.

Description

Artificial cochlea simulation rapid integration test system

Technical Field

The utility model belongs to the field of medical equipment, in particular to system for testing is integrated fast in artifical cochlea simulation.

Background

The artificial cochlea is a hearing rehabilitation device which converts acoustic signals into electric signals, stimulates a stimulation electrode in the body in a radio frequency mode, and stimulates the auditory nerve of a patient in an electric stimulation mode to recover the hearing. Cochlear implants restore hearing to most severe or extremely severe hearing loss patients, and most cochlear implants can exhibit near normal language understanding in quiet language environments. However, in the using process of a patient, the acoustic effect of the patient is reduced or abnormal sounds are generated due to abnormal stimulation of the electrodes caused by factors such as impact on the implanted part of the patient or diseases of the cochlea, under the condition, stimulation signals of each electrode of the implant body need to be collected and amplified, so that whether the stimulation signals of the electrodes are symmetrical or not and whether the charges are balanced or not are judged, a follow-up machine can focus on the electrodes with the stimulation signals not meeting requirements, even some abnormal stimulation electrodes are closed, and a strict judgment and detection method is provided for judging whether the electrodes are taken out and implanted again.

The rapid integration test is generally carried out when hearing statements appear to be reduced or abnormal sounds exist in the later rehabilitation process of implantation, and if the problem of electrode stimulation which cannot be solved by a software debugging method is found, unnecessary damage to a human body can be caused, and a set of expensive artificial cochlea is wasted.

SUMMERY OF THE UTILITY MODEL

In view of this, the utility model aims at providing a system of artifical cochlea simulation rapid integration test can carry out stimulation signal's detection to implant electrode before implanting effectively, does effectual aassessment to the operating condition of implant, provides effective data for follow-up accent machine, improves uncomfortable neural stimulation.

In order to achieve the above purpose, the utility model provides a system for simulating and rapidly integrating the test of the cochlear prosthesis, which comprises an upper computer, an integration tester, a debugging box, a synchronous signal line, a speech processor, an implant, an electrode wire, an electrode terminal and a salinity tester, wherein the upper computer is respectively connected with the debugging box and the integration tester, the debugging box is also connected with the speech processor, the integration tester is connected with the electrode terminal through the electrode wire, wherein,

the upper computer is configured with acquisition parameters, generates and sends stimulation, receives the acquired data, calculates test data and gives a test result;

the integration tester receives the synchronous signal, and acquires, transmits and amplifies data;

the salinity tester tests the concentration of saline water for placing the implant;

the debugging box converts an instruction sent by the upper computer into a signal which can be accepted by the speech processor, and simultaneously transmits a synchronous signal to the integration tester through a synchronous signal line;

the synchronous signal line transmits a synchronous acquisition signal to the integration tester;

the speech processor receives the signal of the debugging box and sends a stimulation signal to the implant;

the implant receives the stimulation signal and outputs electrical stimulation through the implant electrode;

the electrode terminals include a positive electrode terminal, a negative electrode terminal, and a ground terminal.

Preferably, the integrated tester comprises an electrode terminal signal collector, an ADC sampling module, a gain control module, an analog signal processing module, an analog-to-digital conversion module, a digital signal processing module and a signal output terminal, which are connected in sequence, wherein,

the electrode terminal signal collector collects and inputs the stimulation original voltage signal of the electrode terminal;

the ADC sampling module receives sampling rate configuration and sampling opening instructions of the upper computer, and after the ADC sampling module is opened, the integrated tester starts to collect data;

the gain control module receives a gain configuration instruction of the upper computer and amplifies the acquired voltage signals, wherein the gain comprises 3 grades which are 1.5 times, 7.5 times and 30 times respectively;

the analog signal processing module processes the amplified analog signal;

the analog-to-digital conversion module converts an analog signal into a digital signal;

the digital signal processing module processes the converted digital signal;

and the signal output end transmits the processed digital signal to an upper computer through a serial port line.

Preferably, the speech processor is in positioning wireless connection with the implant receiving coil through a magnet through a speech processor transmitting coil, sends stimulation to the implant receiving coil in a wireless induction mode, and reversely receives data of the implant; the I2C is connected with the debugging box to realize communication with the debugging box;

preferably, the saline is simulated physiological water.

From the higher authority can see, the utility model discloses an adopt the amazing cooperation to stimulation signal acquisition of host computer software and integration tester to the stimulation performance to artificial cochlea implant body electrode has detected, provides the basis for the processing of electrode in the follow-up accent machine, has also avoided implanting back artificial cochlea amazing auditory nerve anomaly, amazing unbalanced charge scheduling problem, when having improved fail safe nature, the cost is also reduced.

Drawings

In order to make the purpose, technical scheme and beneficial effect of the utility model clearer, the utility model provides a explain as follows the attached drawing:

fig. 1 is a block diagram of a cochlear implant simulation rapid integration test system according to an embodiment of the present invention;

fig. 2 is a schematic structural diagram of a cochlear implant simulation rapid integration test system according to an embodiment of the present invention;

fig. 3 is a structural block diagram of an integrated tester of the cochlear implant simulation rapid integrated test system according to the embodiment of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail with reference to the accompanying drawings.

Referring to fig. 1 and 2, a structure diagram of a cochlear implant simulation rapid integration test system according to an embodiment of the present invention includes an upper computer 10, an integration tester 50, a debugging box 20, a synchronization signal line, a speech processor 30, an implant 40, an electrode line 61 and an electrode terminal, the upper computer 10 is connected to the debugging box 20 and the integration tester 50 respectively, the debugging box 20 is further connected to the speech processor 30, the integration tester 50 is connected to the electrode terminal through the electrode line 61, wherein,

the upper computer 10 configures acquisition parameters, generates and sends stimulation, receives acquired data, calculates test data and gives a test result; the integration tester 50 receives the synchronization signal, collects, transmits and amplifies data; the salinity tester 90 tests the concentration of the saline in which the implant 40 is placed; the debugging box 20 converts the instruction sent by the upper computer 10 into a signal which can be accepted by the speech processor 30, and simultaneously transmits a synchronous signal to the integration tester 50 through a synchronous signal line; the synchronous signal line transmits synchronous acquisition signals to the integration tester 50, both ends of the synchronous acquisition signals are 3.5mm audio interfaces, one section of the synchronous acquisition signals is connected with the EP port of the debugging box 20, the other end of the synchronous acquisition signals is connected with the trigger signal port of the integration tester 50, and synchronous signals sent by the debugging box 20 are transmitted to the integration tester 50 through the synchronous signal line; the speech processor 30 receives the signal from the fitting box 20 and sends a stimulation signal to the implant 40; the implant 40 receives the stimulation signal and outputs electrical stimulation through the electrode of the implant 40 (the implant 40 is specifically referred to as the implant electrode in fig. 2); the electrode terminals include a positive electrode terminal 60, a negative electrode terminal 70, and a ground terminal 80.

Referring to fig. 3, the integration tester 50 includes an electrode terminal signal collector 51, an ADC sampling module 52, a gain control module 53, an analog signal processing module 54, an analog-to-digital conversion module 55, a digital signal processing module 56, and a signal output terminal 57, which are connected in sequence, wherein,

the electrode terminal signal collector 51 collects and inputs the stimulation original voltage signal of the electrode terminal; the ADC sampling module 52 receives a sampling rate configuration and a sampling opening instruction of the upper computer 10, and when the ADC sampling module 52 is opened, the integration tester 50 starts to collect data; the gain control module 53 receives a gain configuration instruction of the upper computer 10 and amplifies the acquired voltage signal; the analog signal processing module 54 processes the amplified analog signal; the analog-to-digital conversion module 55 converts the analog signal into a digital signal; the digital signal processing module 56 processes the converted digital signal; the signal output terminal 57 transmits the processed digital signal to the upper computer 10 through a serial port line.

The speech processor 30 is in positioning wireless connection with the implant receiving coil 41 through a magnet through the speech processor transmitting coil 31, sends stimulation to the implant receiving coil 41 through a wireless induction mode, and reversely receives data of the implant 40; and the I2C is connected with the debugging box 20 to realize communication with the debugging box 20.

Saline is simulated physiological water, and the simulated physiological water is defined as: mixing with 0.9% normal saline and purified water, wherein the salt concentration is 1.5-1.6 ‰.

Adopt the utility model relates to a method of artifical cochlea simulation rapid integration test system, including following step:

s10, taking a cuboid container with the length of 80-100mm, the width of 80-100mm, the height of 150-200mm and the wall thickness of 2-3mm, attaching an implant receiving coil to the side wall of the container, placing a stimulation electrode of an implant along the wall of the container, arranging a speech processor on the outer wall of the container, and adsorbing a speech processor transmitting coil with the implant receiving coil through a partition plate with the thickness of 4-6 mm;

s20, attaching the positive electrode end and the negative electrode end of the electrode wire to the other two side walls of the container respectively, attaching the grounding end to the bottom of the container wall, connecting the other end of the electrode wire to the input end of an integration tester, and connecting the integration tester to an upper computer through a serial port line;

s30, blending 0.9% of normal saline and purified water into saline with the salt concentration of 1.5-1.6 per mill in a container, wherein the saline at least completely submerges the implant and the electrode end of the electrode wire;

s40, setting the sampling rate of the integrated tester to 500000Hz, setting the gain to be 7.5 times, and testing the electrode impedance in the saline water;

s50, the speech processor is connected with an upper computer through a debugging box, the debugging box is connected with a synchronous interface of the integration tester through a synchronous signal line, and a transmitting coil of the speech processor is attached to a receiving coil of the implant;

s60, carrying out impedance measurement on each stimulating electrode of the implant, and confirming the electrode numbers of short circuit and open circuit;

s70, scanning and stimulating all the electrodes with impedance within a preset range under different current sources, different stimulation modes and different stimulation amplitudes, collecting and amplifying actual stimulation signals, calculating the positive-negative charge symmetry ratio and the positive-negative amplitude symmetry ratio of the electrode stimulation signals, and obtaining stimulation normal electrodes, stimulation electrodes with potential risks, stimulation electrodes with greater risks and stimulation abnormal electrodes according to the results of the charge symmetry ratio and the amplitude symmetry ratio.

The saline impedance values at the positive and negative electrode terminals tested in S40 are no greater than 5k Ω, otherwise the integrated tester needs to be recalibrated.

In S60, electrode impedance measurement simultaneously adopts two worm outer electrodes MP1 and MP2 as loop electrodes for impedance test, a P _ N current source is used as a current source, the pulse width is 50us, and the pulse interval is 10us.

In S70, the stimulation signal is a negative phase pulse first, then a positive phase pulse, and there is an interval between the negative and positive pulses, the current sources are N mode No. 1 current source, N mode No. 2 current source, P _ N mode No. 1 current source, and P _ N mode No. 2 current source, the amplitude is set to 66 current units and 132 current units, the stimulation mode is MP1+2, the pulse width is 50us, and the pulse interval is 10us.

S70, the positive-negative charge symmetry ratio and the amplitude symmetry ratio of a stimulation signal for stimulating the normal electrode are between 0.90 and 1.10; the positive-negative charge symmetry ratio and the amplitude symmetry ratio of a stimulation signal for stimulating the electrode with the potential risk are between 0.75 and 0.90 or 1.10 and 1.25; the positive-negative charge symmetry ratio and the amplitude symmetry ratio of a stimulation signal for stimulating the electrode with the greater risk are between 0.50 and 0.75 or between 1.25 and 1.50; the stimulation signal positive-negative charge symmetry ratio and the amplitude symmetry ratio of the stimulation abnormal electrode are less than 0.50 or more than 1.50.

After the stimulation signal parameters were calculated, acquisition was stopped and the symmetry ratio curves for all electrodes were plotted as background recordings.

Finally, while the invention has been described in detail with reference to a preferred embodiment thereof, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the scope of the invention encompassed by the appended claims.

Claims

1. A simulated rapid integrated test system for cochlear implants is characterized by comprising an upper computer, an integrated tester, a debugging box, a synchronous signal line, a speech processor, an implant, an electrode wire, an electrode terminal and a salinity tester, wherein the upper computer is respectively connected with the debugging box and the integrated tester, the debugging box is connected with the speech processor, the integrated tester is connected with the electrode terminal through the electrode wire,

the debugging box converts the instruction sent by the upper computer into a signal which can be accepted by the speech processor, and simultaneously transmits a synchronous signal to the integration tester through a synchronous signal line;

2. The cochlear implant simulation rapid integration test system according to claim 1, wherein the integration tester comprises an electrode terminal signal collector, an ADC sampling module, a gain control module, an analog signal processing module, an analog-to-digital conversion module, a digital signal processing module and a signal output terminal which are connected in sequence, wherein,

the gain control module receives a gain configuration instruction of the upper computer and amplifies the acquired voltage signal, wherein the gain comprises 3 grades which are 1.5 times, 7.5 times and 30 times respectively;

the analog signal processing module processes the amplified analog signal;

the digital signal processing module processes the converted digital signal;

3. The cochlear implant simulation rapid integration test system according to claim 1, wherein the speech processor is wirelessly connected with the implant receiving coil through a speech processor transmitting coil in a magnet positioning manner, sends stimulation to the implant receiving coil in a wireless induction manner, and reversely receives data of the implant; and the I2C is connected with the debugging box to realize communication with the debugging box.

4. The cochlear implant simulation rapid integration test system of claim 1, wherein the saline is 0.9% saline.