CN218106029U - High-voltage transmitting circuit for catheter and ablation tool - Google Patents
High-voltage transmitting circuit for catheter and ablation tool Download PDFInfo
- Publication number
- CN218106029U CN218106029U CN202121773682.1U CN202121773682U CN218106029U CN 218106029 U CN218106029 U CN 218106029U CN 202121773682 U CN202121773682 U CN 202121773682U CN 218106029 U CN218106029 U CN 218106029U
- Authority
- CN
- China
- Prior art keywords
- electrode
- voltage
- high voltage
- transmitting circuit
- switching tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Electrotherapy Devices (AREA)
Abstract
The utility model discloses a high-pressure transmitting circuit and ablation instrument for pipe is provided with first electrode and second electrode on the pipe, and high-pressure transmitting circuit includes: the transmitting end of the first transmitting circuit is connected with the first electrode and is used for outputting positive high voltage, negative high voltage or zero voltage to the first electrode; the transmitting end of the second transmitting circuit is connected with the second electrode and is used for outputting positive high voltage, negative high voltage or zero voltage to the second electrode; the control circuit is respectively connected with the first transmitting circuit and the second transmitting circuit and used for controlling the first transmitting circuit and the second transmitting circuit so as to form positive high voltage, negative high voltage, double high voltage or zero voltage between the first electrode and the second electrode. Therefore, the precise control and flexible adjustment of the pulse voltage of the catheter are realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved to a great extent.
Description
Technical Field
The utility model relates to a pulsed electric field melts technical field, especially relates to a high-voltage transmitting circuit and melts instrument for pipe.
Background
The ablation energy in the catheter ablation technology adopted for treating arrhythmia at present is mainly radio frequency energy and is assisted by freezing energy, and the two ablation modes have certain superiority in treating arrhythmia and have corresponding limitations, for example, the ablation energy has no selectivity for damaging tissues in an ablation area, and certain damage can be caused to adjacent esophagus, coronary artery, phrenic nerve and the like depending on the adhesion force of a catheter, so that the related technology of finding a quick, safe and efficient ablation energy to complete and achieve persistent pulmonary vein isolation without damaging adjacent tissues becomes a hotspot of research.
Pulsed electric field ablation is a new type of ablation using pulsed electric field as energy, and is gaining attention as a non-thermal ablation technique in clinical application. The pulsed electric field ablation technology is mainly characterized in that a high-voltage pulsed electric field with the pulse width of millisecond, microsecond or even nanosecond is generated, extremely high energy is released in a short time, and a cell membrane, even intracellular organelles such as endoplasmic reticulum, mitochondria, cell nucleus and the like can generate a large number of irreversible micropores, so that apoptosis of pathological cells is caused, and the expected treatment purpose is achieved. However, as a novel energy ablation technology, pulsed electric field ablation has the defects of inaccurate pulse voltage control, inflexible pulse voltage adjustment and the like, so that the application of the pulsed electric field ablation technology in clinic is limited.
SUMMERY OF THE UTILITY MODEL
The present invention aims at solving at least one of the technical problems in the related art to a certain extent. Therefore, the utility model discloses a first aim at provides a high-voltage transmitting circuit for pipe, and this circuit has realized accurate control and the nimble adjustable of pipe impulse voltage, has satisfied the treatment demand among the multiple pulsed electric field ablation operation, and to a great extent has improved the application prospect of pulsed electric field ablation technique on arrhythmia treatment.
A second object of the present invention is to provide an ablation instrument.
In order to achieve the above object, an embodiment of the present invention provides a high voltage transmitting circuit for a catheter, wherein the catheter is provided with a first electrode and a second electrode, and the high voltage transmitting circuit includes: the first end of the first transmitting circuit is connected with the high-voltage anode, the second end of the first transmitting circuit is connected with the high-voltage ground, the third end of the first transmitting circuit is connected with the high-voltage cathode, and the transmitting end of the first transmitting circuit is connected with the first electrode and used for outputting positive high voltage, negative high voltage or zero voltage to the first electrode; the first end of the second transmitting circuit is connected with the high-voltage anode, the second end of the second transmitting circuit is connected with a high-voltage ground, the third end of the second transmitting circuit is connected with the high-voltage cathode, and the transmitting end of the second transmitting circuit is connected with the second electrode and used for outputting positive high voltage, negative high voltage or zero voltage to the second electrode; and the control circuit is respectively connected with the first transmitting circuit and the second transmitting circuit and is used for controlling the first transmitting circuit and the second transmitting circuit so as to form positive high voltage, negative high voltage, double high voltage or zero voltage between the first electrode and the second electrode.
According to the utility model discloses a high voltage transmitting circuit for pipe, first transmitting circuit links to each other with the first electrode and is used for exporting positive high pressure, burden high pressure or zero voltage to the first electrode, and the second transmitting circuit links to each other with the second electrode and is used for exporting positive high pressure, burden high pressure or zero voltage to the second electrode to control first transmitting circuit and second transmitting circuit so that form positive high pressure, burden high pressure, doubly high pressure or zero voltage between first electrode and the second electrode respectively through control circuit. Therefore, the precise control and flexible adjustment of the pulse voltage of the catheter are realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved to a great extent.
According to an embodiment of the present invention, the first transmitting circuit includes: the first end of the first switch tube is connected with the high-voltage positive electrode, the second end of the first switch tube, the first end of the second switch tube and the first end of the third switch tube are connected with the first electrode, the second end of the second switch tube is connected with the high-voltage ground, the second end of the third switch tube is connected with the high-voltage negative electrode, and the control end of the first switch tube, the control end of the second switch tube and the control end of the third switch tube are respectively connected with the control circuit.
According to the utility model discloses an embodiment, second transmitting circuit includes: the first end of the fourth switch tube is connected with the high-voltage positive electrode, the second end of the fourth switch tube, the first end of the fifth switch tube and the first end of the sixth switch tube are connected with the second electrode, the second end of the fifth switch tube is connected with the high-voltage ground, the second end of the sixth switch tube is connected with the high-voltage negative electrode, and the control end of the fourth switch tube, the control end of the fifth switch tube and the control end of the sixth switch tube are connected with the control circuit respectively.
According to an embodiment of the present invention, when the second electrode is used as a reference electrode, wherein when the first switching tube and the fifth switching tube are in a conducting state, a positive high voltage with the second electrode as the reference electrode is formed between the first electrode and the second electrode; when the third switching tube and the fifth switching tube are in a conducting state, a negative high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode; when the second switching tube and the fifth switching tube are in a conducting state, zero voltage taking the second electrode as a reference electrode is formed between the first electrode and the second electrode; when the first switching tube and the sixth switching tube are in a conducting state, a high voltage which is multiplied by the second electrode as a reference electrode is formed between the first electrode and the second electrode.
According to an embodiment of the present invention, when the first electrode is used as a reference electrode, wherein when the fourth switching tube and the second switching tube are in a conducting state, a positive high voltage with the first electrode as the reference electrode is formed between the first electrode and the second electrode; when the sixth switching tube and the second switching tube are in a conducting state, a negative high voltage taking the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the fifth switching tube and the second switching tube are in a conducting state, zero voltage taking the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the fourth switching tube and the third switching tube are in a conducting state, a high voltage which is multiplied by the first electrode as a reference electrode is formed between the first electrode and the second electrode.
According to the utility model discloses an embodiment, the structure of first switch tube to sixth switch tube is the same, and constitutes by the switch tube of a plurality of reverse connections.
According to the utility model discloses an embodiment, first transmitting circuit still includes: the first resistor is connected between the first end of the first switching tube and the high-voltage positive electrode in series, and the second resistor is connected between the second end of the third switching tube and the high-voltage negative electrode in series.
According to the utility model discloses an embodiment, the second transmitting circuit still includes: the third resistor is connected between the first end of the fourth switching tube and the high-voltage positive electrode in series, and the fourth resistor is connected between the second end of the sixth switching tube and the high-voltage negative electrode in series.
According to the utility model discloses an embodiment, high voltage transmitting circuit still includes: and one end of the sampling resistor is connected with the second end of the first transmitting circuit and the second end of the second transmitting circuit respectively, and the other end of the sampling resistor is connected with a high-voltage ground.
According to the utility model discloses an embodiment, first electrode and second electrode all include a plurality ofly, and every first electrode all corresponds and is provided with first transmitting circuit, and every second electrode all corresponds and is provided with the second transmitting circuit.
In order to achieve the above object, the second aspect of the present invention provides an ablation instrument, including a catheter and a high voltage transmitting circuit for the catheter as in the first aspect.
According to the utility model discloses melt instrument through the above-mentioned high-voltage transmitting circuit who is used for the pipe, has realized accurate control and the nimble adjustable of pipe impulse voltage, has satisfied the treatment demand among the multiple pulse electric field ablation operation, and to a great extent has improved the application prospect of pulse electric field ablation technique on arrhythmia treatment.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
Fig. 1 is a schematic structural diagram of a high voltage transmitting circuit for a catheter according to a first embodiment of the present invention;
fig. 2 is a schematic structural diagram of a high voltage transmitting circuit for a catheter according to a second embodiment of the present invention;
fig. 3 is a pulse voltage waveform diagram for a high voltage transmit circuit for a catheter according to an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a high voltage transmitting circuit for a catheter according to a third embodiment of the present invention;
fig. 5 is a schematic structural diagram of a high voltage transmitting circuit for a catheter according to a fourth embodiment of the present invention;
fig. 6 is a schematic structural diagram of a high voltage transmitting circuit for a catheter according to a fifth embodiment of the present invention;
fig. 7 is a schematic structural view of an ablation instrument according to an embodiment of the present invention.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary and intended to be used for explaining the present invention, and should not be construed as limiting the present invention.
The high voltage transmitting circuit and the ablation tool for the catheter according to the embodiments of the present invention will be described with reference to the accompanying drawings.
Fig. 1 is a schematic structural diagram of a high voltage transmitting circuit for a catheter according to a first embodiment of the present invention, referring to fig. 1, the catheter is provided with a first electrode P1 and a second electrode P2, and the high voltage transmitting circuit includes: a first transmitting circuit 110, a second transmitting circuit 120, and a control circuit 130.
The first end of the first transmitting circuit 110 is connected with the high-voltage positive electrode + HV, the second end of the first transmitting circuit 110 is connected with the high-voltage ground GND, the third end of the first transmitting circuit 110 is connected with the high-voltage negative electrode-HV, and the transmitting end of the first transmitting circuit 110 is connected with the first electrode P1 and used for outputting positive high voltage, negative high voltage or zero voltage to the first electrode P1; the first end of the second transmitting circuit 120 is connected with the high-voltage positive electrode + HV, the second end of the second transmitting circuit 120 is connected with the high-voltage ground GND, the third end of the second transmitting circuit 120 is connected with the high-voltage negative electrode-HV, and the transmitting end of the second transmitting circuit 120 is connected with the second electrode P2 and used for outputting positive high voltage, negative high voltage or zero voltage to the second electrode P2; the control circuit 130 is connected to the first transmitting circuit 110 and the second transmitting circuit 120, respectively, and is configured to control the first transmitting circuit 110 and the second transmitting circuit 120, so as to form a positive high voltage, a negative high voltage, a double high voltage, or a zero voltage between the first electrode P1 and the second electrode P2.
The method is characterized in that a high-voltage pulse electric field with the pulse width of millisecond, microsecond or even nanosecond is generated, extremely high energy is released in a short time, and cell membranes and even intracellular organelles such as endoplasmic reticulum, mitochondria and cell nucleus can generate a large number of irreversible micropores under the action of the high-voltage pulse electric field, so that apoptosis of pathological cells is caused, and the aim of treating rapid arrhythmia is fulfilled.
In practical application, firstly, the heart is subjected to electrophysiological examination through the puncture subclavian vein and the bifilary side vein to clearly diagnose the position of a lesion to be ablated, then the heart is inserted into the lesion position along a blood vessel through a special catheter, and a high-voltage pulse electric field is emitted to the lesion position in a short time through a first electrode P1 and a second electrode P2 arranged on the catheter, so that the function of accurately treating myocardial cells is achieved, and necessary influence on other non-target cell tissues is not generated. In operation, under normal conditions, the control circuit 130 in the high voltage transmitting circuit sends control signals to the first transmitting circuit 110 and the second transmitting circuit 120 respectively to control the first transmitting circuit 110 to output positive high voltage, negative high voltage or zero voltage through the first electrode P1, and control the second transmitting circuit 120 to output positive high voltage, negative high voltage or zero voltage through the second electrode P2, and no matter the first electrode P1 or the second electrode P2 is used as a reference electrode, positive high voltage, negative high voltage, double high voltage or zero voltage can be formed between the first electrode P1 and the second electrode P2, so that flexible control of catheter output pulse voltage is realized, various requirements in pulsed electric field ablation surgery can be met, and due to generation of double high voltage, high voltage positive electrode + HV and high voltage negative electrode-HV can be reduced under the condition that the pulse voltage requirement is small, all maximum pulse voltages can be reached only depending on the formed double high voltage, and accurate control of high voltage pulse signals can be realized.
According to the utility model discloses a high voltage transmitting circuit for pipe, first transmitting circuit links to each other with the first electrode and is used for exporting positive high pressure, burden high pressure or zero voltage to the first electrode, and the second transmitting circuit links to each other with the second electrode and is used for exporting positive high pressure, burden high pressure or zero voltage to the second electrode to control first transmitting circuit and second transmitting circuit so that form positive high pressure, burden high pressure, doubly high pressure or zero voltage between first electrode and the second electrode respectively through control circuit. Therefore, the precise control and flexible adjustment of the pulse voltage of the catheter are realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved to a great extent.
In some embodiments, as shown in fig. 2, the first transmitting circuit 110 includes: the high-voltage switch comprises a first switch tube Q1, a second switch tube Q2 and a third switch tube Q3, wherein the first end of the first switch tube Q1 is connected with a high-voltage anode + HV, the second end of the first switch tube Q1, the first end of the second switch tube Q2 and the first end of the third switch tube Q3 are connected with a first electrode P1, the second end of the second switch tube Q2 is connected with a high-voltage ground GND, the second end of the third switch tube Q3 is connected with a high-voltage cathode-HV, and the control end of the first switch tube Q1, the control end of the second switch tube Q2 and the control end of the third switch tube Q3 are respectively connected with a control circuit 130.
Further, the second transmitting circuit 120 includes: fourth switch tube Q4, fifth switch tube Q5 and sixth switch tube Q6, wherein, the first end of fourth switch tube Q4 links to each other with positive + HV of high pressure, the second end of fourth switch tube Q4, the first end of fifth switch tube Q5 and the first end of sixth switch tube Q6 all link to each other with second electrode P2, the second end of fifth switch tube Q5 links to each other with high-voltage ground GND, the second end of sixth switch tube Q6 links to each other with high-voltage negative pole-HV, the control end of fourth switch tube Q4, the control end of fifth switch tube Q5 and the control end of sixth switch tube Q6 link to each other with control circuit 130 respectively.
Specifically, as shown in fig. 2, the control ends of the first switch tube Q1, the second switch tube Q2 and the third switch tube Q3 in the first transmitting circuit 110 are respectively connected to the control circuit 130, and when the control circuit 130 controls the conduction of the first switch tube Q1 through the control end of the first switch tube Q1, the first electrode P1 is directly connected to the positive high voltage + HV through the first switch tube Q1 to obtain an absolute positive high voltage; when the control circuit 130 controls the second switching tube Q2 to be conducted through the control end of the second switching tube Q2, the first electrode P1 is directly connected with the high-voltage ground GND through the second switching tube Q2 so as to obtain an absolute zero voltage; when the control circuit 130 controls the third switching tube Q3 to be conducted through the control end of the third switching tube Q3, the first electrode P1 is directly connected with the high voltage negative-HV through the third switching tube Q3 so as to obtain an absolute negative high voltage.
Further, the control ends of a fourth switching tube Q4, a fifth switching tube Q5 and a sixth switching tube Q6 in the second transmitting circuit 120 are respectively connected to the control circuit 130, and when the control circuit 130 controls the conduction of the fourth switching tube Q4 through the control end of the fourth switching tube Q4, the second electrode P2 is directly connected to the positive high voltage electrode + HV through the fourth switching tube Q4 so as to obtain an absolute positive high voltage; when the control circuit 130 controls the fifth switching tube Q5 to be turned on through the control end of the fifth switching tube Q5, the second electrode P2 is directly connected with the high-voltage ground GND through the fifth switching tube Q5 so as to obtain an absolute zero voltage; when the control circuit 130 controls the sixth switching tube Q6 to be turned on through the control end of the sixth switching tube Q6, the second electrode P2 is directly connected to the high voltage negative-HV through the sixth switching tube Q6, so as to obtain an absolute negative high voltage.
It should be noted that the first to sixth switching tubes Q1 to Q6 are ideal switching models, and in practical applications, part or all of the first to sixth switching tubes Q1 to Q6 may be implemented by one or more non-ideal switching tubes and some auxiliary components to implement the functions of the ideal switching models, and all of these modifications or alternatives are within the scope of the present application, and are not limited herein.
In some embodiments, when the second electrode P2 serves as a reference electrode, wherein when the first switching tube Q1 and the fifth switching tube Q5 are in a conducting state, a positive high voltage with the second electrode P2 serving as a reference electrode is formed between the first electrode P1 and the second electrode P2; when the third switching tube Q3 and the fifth switching tube Q5 are in a conducting state, a negative high voltage with the second electrode P2 as a reference electrode is formed between the first electrode P1 and the second electrode P2; when the second switching tube Q2 and the fifth switching tube Q5 are in a conducting state, a zero voltage with the second electrode P2 as a reference electrode is formed between the first electrode P1 and the second electrode P2; when the first switching tube Q1 and the sixth switching tube Q6 are in a conducting state, a high voltage which is multiplied by the second electrode P2 as a reference electrode is formed between the first electrode P1 and the second electrode P2.
Further, in some embodiments, when the first electrode P1 serves as a reference electrode, wherein when the fourth switching tube Q4 and the second switching tube Q2 are in a conducting state, a positive high voltage with the first electrode P1 as a reference electrode is formed between the first electrode P1 and the second electrode P2; when the sixth switching tube Q6 and the second switching tube Q2 are in a conducting state, a negative high voltage with the first electrode as a reference electrode is formed between the first electrode P1 and the second electrode P2; when the fifth switching tube Q5 and the second switching tube Q2 are in a conducting state, a zero voltage with the first electrode P1 as a reference electrode is formed between the first electrode P1 and the second electrode P2; when the fourth switching tube Q4 and the third switching tube Q3 are in a conducting state, a high voltage which is multiplied by the first electrode P1 as a reference electrode is formed between the first electrode P1 and the second electrode P2.
Specifically, as shown in fig. 2, the control circuit 130 may control the first and second transmitting circuits 110 and 120 to form a positive high voltage, a negative high voltage, a zero voltage, and a double high voltage between the first and second electrodes P1 and P2.
For example, first, the second electrode P2 is used as a reference electrode, the control circuit 130 can control the fifth switching tube Q5 and the first switching tube Q1 to be in a conducting state, and control the other switching tubes to be in a disconnecting state, at this time, the voltage of the first electrode P1 relative to the second electrode P2 is + HV, a positive high voltage + HV is formed between the first electrode P1 and the second electrode P2, and the voltage is also an absolute positive high voltage; the control circuit 130 can control the third switching tube Q3 and the fifth switching tube Q5 to be in a conducting state, and control the other switching tubes to be in a disconnecting state, at this time, the voltage of the first electrode P1 relative to the second electrode P2 is-HV, a negative high voltage-HV is formed between the first electrode P1 and the second electrode P2, and the voltage is also an absolute negative high voltage; the control circuit 130 can control the second switching tube Q2 and the fifth switching tube Q5 to be in a conducting state, and control the other switching tubes to be in a disconnecting state, at this time, the voltage of the first electrode P1 relative to the second electrode P2 is 0, zero voltage is formed between the first electrode P1 and the second electrode P2, and the voltage is also absolute zero voltage; the control circuit 130 can control the first switch tube Q1 and the sixth switch tube Q6 to be in a conducting state, and control the other switch tubes to be in an off state, at this time, the voltage of the first electrode P1 relative to the second electrode P2 is +2HV, and a double high voltage +2HV is formed between the first electrode P1 and the second electrode P2.
Similarly, with the first electrode P1 as a reference electrode, the control circuit 130 may control the second switching tube Q2 and the fourth switching tube Q4 to be in an on state, and control the other switching tubes to be in an off state, where a voltage of the second electrode P2 relative to the first electrode P1 is + HV, and a positive high voltage + HV is formed between the first electrode P1 and the second electrode P2, where the voltage is also an absolute positive high voltage; the control circuit 130 can control the sixth switching tube Q6 and the second switching tube Q2 to be in a conducting state, and control the other switching tubes to be in a disconnecting state, at this time, the voltage of the second electrode P2 relative to the first electrode P1 is-HV, a negative high voltage-HV is formed between the first electrode P1 and the second electrode P2, and the voltage is also an absolute negative high voltage; the control circuit 130 can control the fifth switching tube Q5 and the second switching tube Q2 to be in a conducting state, and control the other switching tubes to be in a disconnecting state, at this time, the voltage of the second electrode P2 relative to the first electrode P1 is 0, zero voltage is formed between the first electrode P1 and the second electrode P2, and the voltage is also absolute zero voltage; the control circuit 130 can control the third switching tube Q3 and the fourth switching tube Q4 to be in a conducting state, and control the other switching tubes to be in an off state, at this time, the voltage of the second electrode P2 relative to the first electrode P1 is +2HV, and a multiple high voltage +2HV is formed between the first electrode P1 and the second electrode P2.
Further, the first transmitting circuit 110 and the second transmitting circuit 120 may be controlled by the control circuit 130 to form different pulse voltage waveforms, for example, a plurality of different pulse voltage waveforms as shown in fig. 3 may be formed, based on the capability of forming a positive high voltage, a negative high voltage, a zero voltage, and a double high voltage between the first electrode P1 and the second electrode P2.
Specifically, as shown in fig. 2-3, when the fifth switching tube Q5 is turned on, and the first switching tube Q1 is turned on and the remaining switching tubes are turned off, the voltage of the first electrode P1 with respect to the second electrode P2 is + HV, and when the first switching tube Q1 is turned off, the second switching tube Q2 is turned on and the remaining switching tubes are kept off, the voltage of the first electrode P1 with respect to the second electrode P2 is 0, and the control circuit 130 controls the on/off of the first switching tube Q1 and the second switching tube Q2 in a cyclic manner, so as to obtain the pulse voltage waveform shown in fig. 3 (a).
When the fifth switching transistor Q5 is turned on, and the third switching transistor Q3 is turned on and the remaining switching transistors are turned off, the voltage of the first electrode P1 with respect to the second electrode P2 is-HV, and when the third switching transistor Q3 is turned off, the second switching transistor Q2 is turned on, and the remaining switching transistors are kept off, the voltage of the first electrode P1 with respect to the second electrode P2 is 0, and the control circuit 130 controls the on/off of the third switching transistor Q3 and the second switching transistor Q2 in a circulating manner, so that a pulse voltage waveform as shown in fig. 3 (b) can be obtained.
When the sixth switching tube Q6 is in a conducting state, if the first switching tube Q1 is turned on and the remaining switching tubes are turned off, the voltage of the first electrode P1 with respect to the second electrode P2 is +2HV, and when the first switching tube Q1 is turned off, the third switching tube Q3 is turned on and the remaining switching tubes are kept in a disconnected state, the voltage of the first electrode P1 with respect to the second electrode P2 is 0, and the control circuit 130 controls the on/off of the first switching tube Q1 and the third switching tube Q3 cyclically, so that a pulse voltage waveform as shown in fig. 3 (c) can be obtained.
When the fifth switching tube Q5 is in a conducting state, if the first switching tube Q1 is turned on and the remaining switching tubes are turned off, the voltage of the first electrode P1 with respect to the second electrode P2 is + HV, and when the first switching tube Q1 is turned off, the second switching tube Q2 is turned on and the remaining switching tubes are kept in a disconnected state, the voltage of the first electrode P1 with respect to the second electrode P2 is 0, and then when the second switching tube Q2 is turned off, the third switching tube Q3 is turned on and the remaining switching tubes are kept in a disconnected state, the voltage of the first electrode P1 with respect to the second electrode P2 is-HV, and the on/off of the first switching tube Q1, the second switching tube Q2 and the third switching tube Q3 is controlled cyclically in order by the control circuit 130, so that a pulse voltage waveform as shown in fig. 3 (d) can be obtained.
When the fifth switching tube Q5 is in a conducting state, if the first switching tube Q1 is turned on and the other switching tubes are turned off, the voltage of the first electrode P1 with respect to the second electrode P2 is + HV, and when the first switching tube Q1 is turned off, the third switching tube Q3 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode P1 with respect to the second electrode P2 is-HV, and then when the third switching tube Q3 is turned off, the second switching tube Q2 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode P1 with respect to the second electrode P2 is 0, and the on/off of the first switching tube Q1, the third switching tube Q3 and the second switching tube Q2 is cyclically controlled in sequence by the control circuit 130, so that a pulse voltage waveform as shown in fig. 3 (e) can be obtained.
When the fifth switching tube Q5 is in a conducting state, if the third switching tube Q3 is turned on and the other switching tubes are turned off, the voltage of the first electrode P1 with respect to the second electrode P2 is-HV, and when the third switching tube Q3 is turned off, the first switching tube Q1 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode P1 with respect to the second electrode P2 is + HV, and then when the first switching tube Q1 is turned off, the second switching tube Q2 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode P1 with respect to the second electrode P2 is 0, and the on/off of the third switching tube Q3, the first switching tube Q1 and the second switching tube Q2 is cyclically controlled in order by the control circuit 130, so that a pulse voltage waveform as shown in fig. 3 (f) can be obtained.
In practical applications, the control circuit 130 can flexibly control different switching tubes as required to obtain a suitable pulse voltage waveform, for example, when a pulse voltage needs to be increased in the process of treating arrhythmia, the control circuit 130 can control the corresponding switching tubes to adjust the voltage pulse waveform shown in fig. 3 (a) to the voltage pulse waveform shown in fig. 3 (c), so that the voltage pulse can be adjusted at any time, and the flexibility of controlling and adjusting the pulse voltage is improved.
It should be noted that when the first electrode P1 is used as a reference electrode, the pulse voltage shown in fig. 3 can be obtained by controlling the corresponding fourth switching tube Q4, fifth switching tube Q5 and sixth switching tube Q6 in the second transmitting circuit 120, and detailed steps are not repeated. And the foregoing is illustrative only and is not to be taken as a specific limitation of the present application.
In some embodiments, referring to fig. 4, the first to sixth switching tubes Q1 to Q6 have the same structure and are each composed of a plurality of switching tubes connected in opposite directions. Here, two reversely connected switching tubes are taken as an example, and the specific working process refers to the foregoing description, which is not described herein again.
In some embodiments, as illustrated with continued reference to fig. 2, the first transmit circuit 110 further comprises: the first resistor R1 is connected in series between the first end of the first switching tube Q1 and the high voltage positive electrode + HV, and the second resistor R2 is connected in series between the second end of the third switching tube Q3 and the high voltage negative electrode-HV. Further, the second transmitting circuit 120 further includes: the third resistor R3 is connected in series between the first end of the fourth switching tube Q4 and the high-voltage positive electrode + HV, and the fourth resistor R4 is connected in series between the second end of the sixth switching tube Q6 and the high-voltage negative electrode-HV. It should be noted that the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R4 are current-limiting resistors or resistors that prevent current surge, and are used to reduce or prevent transient large current and circuit oscillation caused by parasitic inductance or parasitic capacitance when the system discharges.
In some embodiments, as shown in fig. 5, the high voltage transmitting circuit further comprises: and one end of the sampling resistor R is connected to the second end of the first transmitting circuit 110 and the second end of the second transmitting circuit 120 respectively, and the other end of the sampling resistor R is connected to the high-voltage ground GND for detecting high-voltage discharge during use.
Optionally, referring to fig. 6, the first electrode and the second electrode each include a plurality of electrodes, each first electrode is provided with a first transmitting circuit correspondingly, and each second electrode is provided with a second transmitting circuit correspondingly.
That is, the high voltage transmitting circuit in the present application may be configured by a plurality of first transmitting circuits and second transmitting circuits connected in parallel to output voltages to the plurality of first electrodes and second electrodes so as to form a desired pulse voltage between the plurality of first electrodes and second electrodes. In the using process, any electrode can be selected as a reference electrode according to the requirement, for example, P1 can be selected as the reference electrode, P2, pn and the like can also be selected as the reference electrode, and similarly, any electrode can be selected as a working electrode in a series of electrodes, so that the output polarity can be exchanged, the current loop can be flexibly adjusted, that is, two electrodes can be matched and used at will. In addition, because the electrodes are arranged at different positions of the catheter, the working electrode can be adjusted at will according to the position of a focus in the pulse voltage ablation treatment process without moving the catheter in a large range to enable the electrode to be aligned with the focus, the operability of the pulse voltage ablation technology is improved, and the operation difficulty is reduced.
In summary, the first transmitting circuit is connected to the first electrode for outputting a positive high voltage, a negative high voltage or a zero voltage to the first electrode, the second transmitting circuit is connected to the second electrode for outputting a positive high voltage, a negative high voltage or a zero voltage to the second electrode, and the control circuit controls the first transmitting circuit and the second transmitting circuit respectively to form a positive high voltage, a negative high voltage, a double high voltage or a zero voltage between the first electrode and the second electrode. Therefore, the precise control and flexible adjustment of the pulse voltage of the catheter are realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved to a great extent.
Fig. 7 is a schematic structural diagram of an ablation instrument according to an embodiment of the present invention, and referring to fig. 7, the ablation instrument 1000 includes the high voltage transmitting circuit 100 for a catheter and the catheter 200.
According to the utility model discloses melt instrument, through foretell catheter impulse voltage's accurate control, realized catheter impulse voltage's accurate control and nimble adjustable, satisfied the treatment demand among the multiple pulsed electric field ablation operation, to a great extent has improved the application prospect of pulsed electric field ablation technique on arrhythmia treatment.
It should be noted that the logic and/or steps represented in the flowcharts or otherwise described herein, such as an ordered listing of executable instructions that can be considered to implement logical functions, can be embodied in any computer-readable medium for use by or in connection with an instruction execution system, apparatus, or device, such as a computer-based system, processor-containing system, or other system that can fetch the instructions from the instruction execution system, apparatus, or device and execute the instructions. For the purposes of this description, a "computer-readable medium" can be any means that can contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device. More specific examples (a non-exhaustive list) of the computer-readable medium would include the following: an electrical connection (electronic device) having one or more wires, a portable computer diskette (magnetic device), a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber device, and a portable compact disc read-only memory (CDROM). Additionally, the computer-readable medium could even be paper or another suitable medium upon which the program is printed, as the program can be electronically captured, via for instance optical scanning of the paper or other medium, then compiled, interpreted or otherwise processed in a suitable manner if necessary, and then stored in a computer memory.
It should be understood that portions of the present invention may be implemented in hardware, software, firmware, or a combination thereof. In the above embodiments, the various steps or methods may be implemented in software or firmware stored in memory and executed by a suitable instruction execution system. For example, if implemented in hardware, as in another embodiment, any one or combination of the following techniques, which are known in the art, may be used: a discrete logic circuit having a logic gate circuit for implementing a logic function on a data signal, an application specific integrated circuit having a suitable combinational logic gate circuit, a Programmable Gate Array (PGA), a Field Programmable Gate Array (FPGA), an MCU, a DSP, and the like.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be interconnected within two elements or in a relationship where two elements interact with each other unless otherwise specifically limited. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
Although embodiments of the present invention have been shown and described, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art without departing from the scope of the present invention.
Claims (10)
1. A high voltage transmitting circuit for a catheter, wherein a first electrode and a second electrode are disposed on the catheter, the high voltage transmitting circuit comprising:
the first end of the first transmitting circuit is connected with a high-voltage anode, the second end of the first transmitting circuit is connected with a high-voltage ground, the third end of the first transmitting circuit is connected with a high-voltage cathode, and the transmitting end of the first transmitting circuit is connected with the first electrode and used for outputting positive high voltage, negative high voltage or zero voltage to the first electrode;
a first end of the second transmitting circuit is connected with the high-voltage anode, a second end of the second transmitting circuit is connected with the high-voltage ground, a third end of the second transmitting circuit is connected with the high-voltage cathode, and a transmitting end of the second transmitting circuit is connected with the second electrode and used for outputting positive high voltage, negative high voltage or zero voltage to the second electrode;
and the control circuit is respectively connected with the first transmitting circuit and the second transmitting circuit and is used for controlling the first transmitting circuit and the second transmitting circuit so as to form positive high voltage, negative high voltage, double high voltage or zero voltage between the first electrode and the second electrode.
2. The high voltage transmit circuit for a catheter of claim 1, wherein the first transmit circuit comprises: the high-voltage switch comprises a first switch tube, a second switch tube and a third switch tube, wherein the first end of the first switch tube is connected with the high-voltage positive electrode, the second end of the first switch tube, the first end of the second switch tube and the first end of the third switch tube are connected with the first electrode, the second end of the second switch tube is connected with the high-voltage ground, the second end of the third switch tube is connected with the high-voltage negative electrode, and the control end of the first switch tube, the control end of the second switch tube and the control end of the third switch tube are respectively connected with the control circuit.
3. The high voltage transmit circuit for a catheter of claim 2, wherein the second transmit circuit comprises: fourth switch tube, fifth switch tube and sixth switch tube, wherein, the first end of fourth switch tube with the high-pressure positive pole links to each other, the second end of fourth switch tube the first end of fifth switch tube with the first end of sixth switch tube all with the second electrode links to each other, the second end of fifth switch tube with link to each other high-voltage ground, the second end of sixth switch tube with the high-pressure negative pole links to each other, the control end of fourth switch tube the control end of fifth switch tube with the control end of sixth switch tube respectively with control circuit links to each other.
4. The high voltage transmit circuit for a catheter of claim 3, wherein when the second electrode is used as a reference electrode, wherein,
when the first switching tube and the fifth switching tube are in a conducting state, a positive high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode;
when the third switching tube and the fifth switching tube are in a conducting state, a negative high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode;
when the second switching tube and the fifth switching tube are in a conducting state, a zero voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode;
when the first switching tube and the sixth switching tube are in a conducting state, a high voltage which is multiplied by the second electrode as a reference electrode is formed between the first electrode and the second electrode.
5. The high voltage transmit circuit for a catheter of claim 3, wherein when the first electrode is a reference electrode, wherein,
when the fourth switching tube and the second switching tube are in a conducting state, a positive high voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode;
when the sixth switching tube and the second switching tube are in a conducting state, a negative high voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode;
when the fifth switching tube and the second switching tube are in a conducting state, a zero voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode;
when the fourth switching tube and the third switching tube are in a conducting state, a high voltage which is multiplied by the first electrode as a reference electrode is formed between the first electrode and the second electrode.
6. The high voltage transmitting circuit for the conduit according to claim 3, wherein the first switch tube to the sixth switch tube have the same structure and are each composed of a plurality of switch tubes connected in opposite directions.
7. The high voltage transmit circuit for a conduit of any one of claims 3-6,
the first transmission circuit further includes: the first resistor is connected between the first end of the first switching tube and the high-voltage positive electrode in series, and the second resistor is connected between the second end of the third switching tube and the high-voltage negative electrode in series;
the second transmitting circuit further includes: the third resistor is connected between the first end of the fourth switching tube and the high-voltage positive electrode in series, and the fourth resistor is connected between the second end of the sixth switching tube and the high-voltage negative electrode in series.
8. The high voltage transmit circuit for a catheter of claim 1, further comprising: and one end of the sampling resistor is connected with the second end of the first transmitting circuit and the second end of the second transmitting circuit respectively, and the other end of the sampling resistor is connected with the high-voltage ground.
9. The high voltage transmit circuit for a catheter of any of claims 1-6, wherein the first electrode and the second electrode each comprise a plurality, each of the first electrodes is provided with the first transmit circuit and each of the second electrodes is provided with the second transmit circuit.
10. An ablation instrument comprising a catheter and a high voltage firing circuit for a catheter as claimed in any of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121773682.1U CN218106029U (en) | 2021-07-30 | 2021-07-30 | High-voltage transmitting circuit for catheter and ablation tool |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121773682.1U CN218106029U (en) | 2021-07-30 | 2021-07-30 | High-voltage transmitting circuit for catheter and ablation tool |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218106029U true CN218106029U (en) | 2022-12-23 |
Family
ID=84494246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121773682.1U Active CN218106029U (en) | 2021-07-30 | 2021-07-30 | High-voltage transmitting circuit for catheter and ablation tool |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218106029U (en) |
-
2021
- 2021-07-30 CN CN202121773682.1U patent/CN218106029U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111248994B (en) | Modulating delivery of irreversible electroporation pulses based on transferred energy | |
| JP2021164638A (en) | Basket catheter with solid conducting spines as electrodes for ire | |
| EP2322108B1 (en) | Class resonant-H electrosurgical generators | |
| CN112535528A (en) | Pulse generator for irreversible electroporation | |
| EP2404564B1 (en) | Current-fed push-pull converter with passive voltage clamp | |
| CN113768612B (en) | High voltage transmitting circuit for catheter and ablation instrument | |
| EP2901940A3 (en) | Surgical generator for ultrasonic devices and for electrosurgical devices | |
| CN113648044A (en) | High-voltage transmitting circuit for catheter and ablation tool | |
| CN104901630A (en) | Radio frequency adjustable phase difference power amplifier circuit realizing linear ablation | |
| CN215739390U (en) | Switching device for composite radio frequency and irreversible electroporation | |
| CN109999340A (en) | A kind of loaded self-adaptive nanosecond pulse generation device | |
| CN218106029U (en) | High-voltage transmitting circuit for catheter and ablation tool | |
| CN113648045A (en) | High-voltage transmitting circuit for catheter and ablation tool | |
| EP4074272B1 (en) | Pulse generator for irreversible electroporation with switchable pulse application | |
| CN114869453A (en) | Steep pulse electric field ablation control system | |
| CN215349403U (en) | Ablation device and radio frequency ablation equipment | |
| CN216908099U (en) | High-voltage transmitting circuit for catheter and ablation tool | |
| CN215349402U (en) | Ablation device and radio frequency ablation equipment | |
| CN215349406U (en) | Ablation device and radio frequency ablation equipment | |
| CN218165361U (en) | Pulsed electric field ablation apparatus | |
| CN117100386A (en) | pulse ablation system | |
| CN117064536A (en) | Pulse cell ablation nanometer knife | |
| CN113662650B (en) | High voltage generating circuit for catheter and ablation instrument | |
| CN115733467A (en) | Pulse generating circuit, device, equipment and method | |
| CN115005961A (en) | Cardiac pulse electric field ablation system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |