CN113648045A - High-voltage transmitting circuit for catheter and ablation tool - Google Patents
High-voltage transmitting circuit for catheter and ablation tool Download PDFInfo
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- CN113648045A CN113648045A CN202110875452.4A CN202110875452A CN113648045A CN 113648045 A CN113648045 A CN 113648045A CN 202110875452 A CN202110875452 A CN 202110875452A CN 113648045 A CN113648045 A CN 113648045A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
- A61B2018/00375—Ostium, e.g. ostium of pulmonary vein or artery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00613—Irreversible electroporation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00767—Voltage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/0091—Handpieces of the surgical instrument or device
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/0091—Handpieces of the surgical instrument or device
- A61B2018/00916—Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device
- A61B2018/00922—Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device by switching or controlling the treatment energy directly within the hand-piece
Abstract
The invention discloses a high-voltage transmitting circuit and an ablation tool for a catheter, wherein a plurality of first electrodes and a plurality of second electrodes are arranged on the catheter, and the high-voltage transmitting circuit comprises: the device comprises a first transmitting circuit, a second transmitting circuit, a first switch circuit, a second switch circuit and a control circuit, wherein the first transmitting circuit is connected with a plurality of first electrodes through the first switch circuit; the second transmitting circuit is connected with the plurality of second electrodes through a second switching circuit; the control circuit controls the first transmitting circuit, the second transmitting circuit, the first switch circuit and the second switch circuit to enable positive high voltage, negative high voltage, zero voltage or double high voltage to be formed between any first electrode and any second electrode. Therefore, by controlling the on-off between the transmitting circuit and the transmitting electrodes, the flexible adjustment of the pulse voltage between any two transmitting electrodes is realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved to a great extent.
Description
Technical Field
The invention relates to the technical field of pulsed electric field ablation, in particular to a high-voltage transmitting circuit for a catheter and an ablation tool.
Background
The existing catheter ablation technology for treating arrhythmia usually uses radiofrequency energy as the main ablation energy and uses cryo-energy as the auxiliary ablation energy, and these two ablation methods have shown certain advantages in treating arrhythmia, and have corresponding limitations, for example, ablation energy lacks selectivity for destroying tissues in ablation region, and depending on the sticking force of the catheter, may cause certain damage to the adjacent esophagus, coronary artery and phrenic nerve, etc., so it is a hot point of research to find a related technology that is fast, safe and efficient to complete and achieve persistent pulmonary vein isolation without injuring adjacent tissues.
Pulsed electric field ablation is a new type of ablation using pulsed electric field as energy, and is gaining attention as a non-thermal ablation technique in clinical application. The pulsed electric field ablation technology is mainly characterized in that a high-voltage pulsed electric field with the pulse width of millisecond, microsecond or even nanosecond is generated, extremely high energy is released in a short time, and a cell membrane, even intracellular organelles such as endoplasmic reticulum, mitochondria, cell nucleus and the like can generate a large number of irreversible micropores, so that apoptosis of pathological cells is caused, and the expected treatment purpose is achieved. However, as a new energy ablation technology, the pulsed electric field ablation technology faces the defect of inflexible adjustment of the pulse voltage between the transmitting electrodes, thereby limiting the clinical application of the pulsed electric field ablation technology.
Disclosure of Invention
The present invention is directed to solving, at least to some extent, one of the technical problems in the related art. Therefore, the first purpose of the invention is to provide a high-voltage transmitting circuit for a catheter, which realizes flexible adjustment of pulse voltage between any two transmitting electrodes by controlling the on-off of a switch circuit and the transmitting electrodes, meets the treatment requirements in various pulsed electric field ablation operations, and greatly improves the application prospect of the pulsed electric field ablation technology in arrhythmia treatment.
A second object of the invention is to propose an ablation instrument.
In order to achieve the above object, a first embodiment of the present invention provides a high voltage transmitting circuit for a catheter, the catheter being provided with a plurality of first electrodes and a plurality of second electrodes, the high voltage transmitting circuit comprising: the device comprises a first transmitting circuit, a second transmitting circuit, a first switch circuit, a second switch circuit and a control circuit, wherein the first transmitting circuit is connected with a plurality of first electrodes through the first switch circuit; the second transmitting circuit is connected with the plurality of second electrodes through a second switching circuit; the control circuit is respectively connected with the first transmitting circuit, the second transmitting circuit, the first switch circuit and the second switch circuit and is used for controlling the first transmitting circuit, the second transmitting circuit, the first switch circuit and the second switch circuit so as to form positive high voltage, negative high voltage, zero voltage or double high voltage between any first electrode and any second electrode.
According to the high-voltage transmitting circuit for the catheter of the embodiment of the invention, the first transmitting circuit is connected with the plurality of first electrodes through the first switch circuit, the second transmitting circuit is connected with the plurality of second electrodes through the second switch circuit, and the control circuit respectively controls the first transmitting circuit, the second transmitting circuit, the first switch circuit and the second switch circuit so as to form positive high voltage, negative high voltage, zero voltage or double high voltage between any first electrode and any second electrode. Therefore, by controlling the on-off between the transmitting circuit and the transmitting electrodes, the flexible adjustment of the pulse voltage between any two transmitting electrodes is realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved to a great extent.
According to one embodiment of the present invention, a first transmission circuit includes: the first end of the first switch tube is connected with the high-voltage positive electrode, the second end of the first switch tube is connected with the first end of the second switch tube and provided with a first node, the second end of the second switch tube is connected with a high-voltage ground, the first node is connected with the first electrodes through a first switch circuit, and the control end of the first switch tube and the control end of the second switch tube are respectively connected with the control circuit.
According to one embodiment of the present invention, the second transmission circuit includes: the first end of the third switching tube is connected with the high-voltage positive electrode, the second end of the third switching tube is connected with the first end of the fourth switching tube and is provided with a second node, the second end of the fourth switching tube is connected with a high-voltage ground, the second node is connected with the second electrodes through a second switching circuit, and the control end of the third switching tube and the control end of the fourth switching tube are respectively connected with the control circuit.
According to an embodiment of the present invention, when the second electrode is a reference electrode, wherein when the first switching tube and the fourth switching tube are both in a conducting state, a positive high voltage with the second electrode as the reference electrode is formed between the first electrode and the second electrode; when the second switching tube and the third switching tube are both in a conducting state, a negative high voltage taking the second electrode as a reference electrode is formed between the first electrode and the second electrode; when the second switching tube and the fourth switching tube are both in a conducting state, zero voltage taking the second electrode as a reference electrode is formed between the first electrode and the second electrode.
According to an embodiment of the present invention, when the first electrode is a reference electrode, wherein when the third switching tube and the second switching tube are both in a conducting state, a positive high voltage with the first electrode as the reference electrode is formed between the first electrode and the second electrode; when the fourth switching tube and the first switching tube are both in a conducting state, a negative high voltage taking the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the fourth switching tube and the second switching tube are both in a conducting state, zero voltage taking the first electrode as a reference electrode is formed between the first electrode and the second electrode.
According to an embodiment of the present invention, the first transmitting circuit further includes a fifth switching tube, a first end of the fifth switching tube is connected to the first node, a second end of the fifth switching tube is connected to the high-voltage negative electrode, and a control end of the fifth switching tube is connected to the control circuit; the second transmitting circuit further comprises a sixth switching tube, the first end of the sixth switching tube is connected with the second node, the second end of the sixth switching tube is connected with the high-voltage negative electrode, and the control end of the sixth switching tube is connected with the control circuit.
According to an embodiment of the present invention, when the second electrode is a reference electrode, wherein when the first switching tube and the fourth switching tube are in a conducting state, a positive high voltage with the second electrode as the reference electrode is formed between the first electrode and the second electrode; when the fifth switching tube and the fourth switching tube are in a conducting state, a negative high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode; when the second switching tube and the fourth switching tube are in a conducting state, zero voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode; when the first switching tube and the sixth switching tube are in a conducting state, a high voltage which is multiplied by the second electrode as a reference electrode is formed between the first electrode and the second electrode.
According to an embodiment of the present invention, when the first electrode is a reference electrode, wherein when the third switching tube and the second switching tube are in a conducting state, a positive high voltage with the first electrode as the reference electrode is formed between the first electrode and the second electrode; when the sixth switching tube and the second switching tube are in a conducting state, a negative high voltage taking the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the fourth switching tube and the second switching tube are in a conducting state, zero voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the third switching tube and the fifth switching tube are in a conducting state, a high voltage which is multiplied by the first electrode as a reference electrode is formed between the first electrode and the second electrode.
According to one embodiment of the invention, the first switch tube to the sixth switch tube have the same structure and are respectively composed of a plurality of switch tubes which are reversely connected.
According to an embodiment of the present invention, the first transmitting circuit further includes a first resistor and a second resistor, the first resistor is connected in series between the high-voltage positive electrode and the first end of the first switching tube, and the second resistor is connected in series between the high-voltage negative electrode and the second end of the fifth switching tube; the second transmitting circuit further comprises a third resistor and a fourth resistor, the third resistor is connected between the high-voltage anode and the first end of the third switching tube in series, and the fourth resistor is connected between the high-voltage cathode and the second end of the sixth switching tube in series.
According to one embodiment of the present invention, the first switch circuit includes a plurality of first switches, the plurality of first switches are in one-to-one correspondence with the plurality of first electrodes, and the first switches are connected in series between the first node and the corresponding first electrodes; the second switch circuit comprises a plurality of second switches, the plurality of second switches correspond to the plurality of second electrodes one to one, and the second switches are connected between the second nodes and the corresponding second electrodes in series.
In order to achieve the above object, a second aspect of the present invention provides an ablation instrument, which includes a catheter and a high voltage transmitting circuit for the catheter as in the first aspect.
According to the ablation tool provided by the embodiment of the invention, through the high-voltage transmitting circuit for the catheter and the control of the on-off between the transmitting circuit and the transmitting electrode, the flexible adjustment of the pulse voltage between any two transmitting electrodes is realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is greatly improved.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
FIG. 1 is a schematic diagram of a high voltage transmit circuit for a catheter according to a first embodiment of the present invention;
FIG. 2 is a schematic diagram of a high voltage transmitting circuit for a catheter according to a second embodiment of the present invention;
FIG. 3 is a waveform of a pulse voltage of the high voltage transmit circuit for the catheter shown in FIG. 2;
FIG. 4 is a schematic diagram of a high voltage transmitting circuit for a catheter according to a third embodiment of the present invention;
FIG. 5 is a waveform of a pulse voltage of the high voltage transmit circuit for the catheter shown in FIG. 4;
FIG. 6 is a schematic diagram of a high voltage transmitting circuit for a catheter according to a fourth embodiment of the present invention;
fig. 7 is a schematic structural view of an ablation instrument in accordance with an embodiment of the invention.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
The high voltage transmitting circuit for a catheter and an ablation instrument according to embodiments of the present invention will be described with reference to the accompanying drawings.
Fig. 1 is a schematic structural diagram of a high voltage transmitting circuit for a catheter according to a first embodiment of the present invention, and referring to fig. 1, the catheter is provided with a plurality of first electrodes and a plurality of second electrodes, the high voltage transmitting circuit includes: a first transmitting circuit 110, a second transmitting circuit 120, a first switching circuit 130, a second switching circuit 140, and a control circuit 150.
Wherein the first transmitting circuit 110 is connected to the plurality of first electrodes through the first switching circuit 130; the second transmitting circuit 120 is connected to the plurality of second electrodes through the second switching circuit 140; the control circuit 150 is connected to the first transmitting circuit 110, the second transmitting circuit 120, the first switch circuit 130, and the second switch circuit 140, respectively, and is configured to control the first transmitting circuit 110, the second transmitting circuit 120, the first switch circuit 130, and the second switch circuit 140, so as to form a positive high voltage, a negative high voltage, a zero voltage, or a multiple high voltage between any first electrode and any second electrode.
The method is characterized in that a high-voltage pulse electric field with the pulse width of millisecond, microsecond or even nanosecond is generated, extremely high energy is released in a short time, and cell membranes and even intracellular organelles such as endoplasmic reticulum, mitochondria and cell nucleus generate a large number of irreversible micropores under the action of the high-voltage pulse electric field, so that apoptosis of pathological cells is caused, and the aim of treating rapid arrhythmia is fulfilled.
In practical application, firstly, the heart is subjected to electrophysiological examination through the puncture subclavian vein and the bifilary side vein to clearly diagnose the position of a lesion to be ablated, then the heart is inserted into the lesion position along a blood vessel through a special catheter, and a high-voltage pulse electric field is emitted to the lesion position in a short time through a first electrode and a second electrode arranged on the catheter, so that the function of accurately treating the myocardial cells is achieved, and necessary influence on other non-target cell tissues is not generated. In operation, under normal conditions, the control circuit 150 in the high voltage transmitting circuit sends control signals to the first transmitting circuit 110, the second transmitting circuit 120, the first switching circuit 130 and the second switching circuit 140, respectively, to control any one or more of the plurality of first electrodes to be connected with the first transmitting circuit 110, and any one or more of the plurality of second electrodes to be connected with the second transmitting circuit 120. For example, the control circuit 150 may control the first electrode P11 to be connected with the first transmitting circuit 110, and the second electrode P21 to be connected with the second transmitting circuit 120, so as to form a positive high voltage, a negative high voltage, a zero voltage or a multiple high voltage between the first electrode P11 and the second electrode P21; alternatively, the control circuit 150 may control the first electrode P11 to be connected with the first transmitting circuit 110, and the second electrode P22 to be connected with the second transmitting circuit 120, so as to realize the formation of a positive high voltage, a negative high voltage, a zero voltage or a multiple high voltage between the first electrode P11 and the second electrode P22; by analogy, positive high voltage, negative high voltage, zero voltage or double high voltage can be formed between the first electrode P11 and any second electrode; in addition, the control circuit 150 can also control the on-off of any first electrode, so as to realize the formation of positive high voltage, negative high voltage, zero voltage or double high voltage between any first electrode and any second electrode, thereby realizing the flexible adjustment of the pulse voltage between any two emission electrodes.
According to the high-voltage transmitting circuit for the catheter of the embodiment of the invention, the first transmitting circuit is connected with the plurality of first electrodes through the first switch circuit, the second transmitting circuit is connected with the plurality of second electrodes through the second switch circuit, and the control circuit respectively controls the first transmitting circuit, the second transmitting circuit, the first switch circuit and the second switch circuit so as to form positive high voltage, negative high voltage, zero voltage or double high voltage between any first electrode and any second electrode. Therefore, by controlling the on-off between the transmitting circuit and the transmitting electrodes, the flexible adjustment of the pulse voltage between any two transmitting electrodes is realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved to a great extent.
In some embodiments, as shown in fig. 2, the first transmitting circuit 110 includes: a first switch Q1 and a second switch Q2, wherein a first end of the first switch Q1 is connected to the high voltage positive electrode + HV, a second end of the first switch Q1 is connected to a first end of the second switch Q2 and has a first node M, a second end of the second switch Q2 is connected to the high voltage ground GND, the first node M is connected to the plurality of first electrodes through the first switch circuit 130, and a control end of the first switch Q1 and a control end of the second switch Q2 are respectively connected to the control circuit 150.
Further, the second transmitting circuit 120 includes: a third switching tube Q3 and a fourth switching tube Q4, wherein a first terminal of the third switching tube Q3 is connected to the high voltage positive electrode + HV, a second terminal of the third switching tube Q3 is connected to a first terminal of the fourth switching tube Q4 and has a second node N, a second terminal of the fourth switching tube Q4 is connected to the high voltage ground GND, the second node N is connected to the plurality of second electrodes through a second switching circuit 140, and a control terminal of the third switching tube Q3 and a control terminal of the fourth switching tube Q4 are respectively connected to the control circuit 150.
Further, the first switch circuit 130 includes a plurality of first switches, the plurality of first switches correspond to the plurality of first electrodes one to one, and the first switches are connected in series between the first node M and the corresponding first electrodes; the second switch circuit 140 includes a plurality of second switches, which are in one-to-one correspondence with the plurality of second electrodes, and are connected in series between the second node N and the corresponding second electrodes.
Specifically, as shown in fig. 2, the control circuit 150 is respectively connected to the first switch Q1, the second switch Q2 and the first switch circuit 130 in the first transmitter circuit 110, and the control circuit 150 can control any first switch in the first switch circuit 130 to be turned on or off so as to make any corresponding first electrode obtain a voltage. When the control circuit 150 controls the conduction of the first switch tube Q1 through the control end of the first switch tube Q1, any first electrode which is switched on is directly connected with the high-voltage positive electrode + HV through the first switch tube Q1 so as to obtain an absolute positive high voltage; when the control circuit 150 controls the second switch tube Q2 to be turned on through the control terminal of the second switch tube Q2, any first electrode that is turned on is directly connected to the high voltage ground GND through the second switch tube Q2 so as to obtain an absolute zero voltage.
Further, the control circuit 150 is respectively connected to the third switching tube Q3, the fourth switching tube Q4 and the second switching circuit 140 in the second transmitting circuit 120, and the control circuit 150 can control any second switch in the second switching circuit 140 to be turned on or off to make any second electrode corresponding to the second switch obtain a voltage. When the control circuit 150 controls the third switching tube Q3 to be conducted through the control end of the third switching tube Q3, any second electrode which is switched on is directly connected with the high-voltage positive electrode + HV through the third switching tube Q3 so as to obtain absolute positive high voltage; when the control circuit 130 controls the fourth switching tube Q4 to be turned on through the control terminal of the fourth switching tube Q4, any second electrode that is turned on is directly connected to the high voltage ground GND through the fourth switching tube Q4 so as to obtain an absolute zero voltage.
In some embodiments, when the second electrode is a reference electrode, wherein when the first switching tube Q1 and the fourth switching tube Q4 are both in a conducting state, a positive high voltage with the second electrode as the reference electrode is formed between the first electrode and the second electrode; when the second switching tube Q2 and the third switching tube Q3 are both in a conducting state, a negative high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode; when the second switch tube Q2 and the fourth switch tube Q4 are both in the on state, a zero voltage with the second electrode as the reference electrode is formed between the first electrode and the second electrode.
Further, in some embodiments, when the first electrode is a reference electrode, wherein when the third switching tube Q3 and the second switching tube Q2 are both in a conducting state, a positive high voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the fourth switching tube Q4 and the first switching tube Q1 are both in a conducting state, a negative high voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the fourth switch tube Q4 and the second switch tube Q2 are both in a conducting state, a zero voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode.
As shown in fig. 2, the control circuit 150 may control the first transmitting circuit 110 and the second transmitting circuit 120 to form a positive high voltage, a negative high voltage, and a zero voltage between any of the first electrodes and the second electrode.
For example, first, with an arbitrarily turned-on second electrode as a reference electrode, the control circuit 150 may control the first switching tube Q1 and the fourth switching tube Q4 to be in an on state, and control the remaining switching tubes to be in an off state, where a voltage of any turned-on first electrode with respect to any turned-on second electrode is + HV, and a positive high voltage + HV is formed between any turned-on first electrode and any turned-on second electrode, and the voltage is also an absolute positive high voltage; the control circuit 150 can control the second switch tube Q2 and the third switch tube Q3 to be in a conducting state, and control the other switch tubes to be in an off state, wherein the voltage of any first electrode which is switched on relative to any second electrode which is switched on is-HV, and a negative high voltage-HV is formed between any first electrode which is switched on and any second electrode which is switched on, and the voltage is a relatively negative high voltage; the control circuit 150 may control the second switch transistor Q2 and the fourth switch transistor Q4 to be in a conducting state, and control the remaining switch transistors to be in a disconnected state, where a voltage of any first electrode that is switched on is 0 with respect to any second electrode that is switched on, and a zero voltage is formed between any first electrode that is switched on and any second electrode that is switched on, and the voltage is also an absolute zero voltage.
Similarly, with any turned-on first electrode as a reference electrode, the control circuit 150 may control the third switching tube Q3 and the second switching tube Q2 to be in a conducting state, and control the remaining switching tubes to be in an off state, where a voltage of any turned-on second electrode with respect to any turned-on first electrode is + HV, and a positive high voltage + HV is formed between any turned-on first electrode and any turned-on second electrode, and the voltage is also an absolute positive high voltage; the control circuit 150 can control the fourth switching tube Q4 and the first switching tube Q1 to be in a conducting state, and control the other switching tubes to be in a disconnected state, at this time, the voltage of any switched-on second electrode relative to any switched-on first electrode is-HV, and a negative high voltage-HV is formed between any switched-on first electrode and any switched-on second electrode, and the voltage is a relatively negative high voltage; the control circuit 150 can control the fourth switch Q4 and the second switch Q2 to be in a conducting state, and control the other switches to be in an off state, where the voltage of any second electrode that is turned on is 0 relative to the voltage of any first electrode that is turned on, and a zero voltage is formed between any first electrode that is turned on and any second electrode that is turned on, and the voltage is also an absolute zero voltage.
Further, based on that positive high voltage, negative high voltage and zero voltage can be formed between any first electrode and any second electrode, in practical application, the control circuit 150 can flexibly control the first transmitting circuit 110 and the second transmitting circuit 120 as required to form different pulse voltage waveforms, so that flexible adjustment of pulse voltage between any two transmitting electrodes is realized, and the requirements of various pulse electric field ablation surgery treatments can be further met.
Specifically, as shown in fig. 2 to 3, when the second electrode P2 is used as a reference electrode, and the second switching tube Q2 is turned on, and the third switching tube Q3 is turned on and the remaining switching tubes are turned off, the voltage of the first electrode with respect to the second electrode is-HV, and when the third switching tube Q3 is turned off, the fourth switching tube Q4 is turned on, and the remaining switching tubes are kept in the off state, the voltage of the first electrode with respect to the second electrode is 0, and the control circuit 150 controls the on/off of the third switching tube Q3 and the fourth switching tube Q4 cyclically, so that the pulse voltage waveform shown in fig. 3(a) can be obtained.
When the fourth switching tube Q4 is in a conducting state, if the first switching tube Q1 is turned on and the other switching tubes are turned off, the voltage of the first electrode relative to the second electrode is + HV, and when the first switching tube Q1 is turned off, the second switching tube Q2 is turned on and the other switching tubes are kept in an off state, the voltage of the first electrode relative to the second electrode is 0, and the on/off of the first switching tube Q1 and the second switching tube Q2 is cyclically controlled by the control circuit 150, so that the pulse voltage waveform shown in fig. 3(b) can be obtained.
When the fourth switching tube Q4 is in a conducting state, if the first switching tube Q1 is turned on and the remaining switching tubes are turned off, the voltage of the first electrode relative to the second electrode is + HV, then, the fourth switch tube Q4 is kept conducting, the first switch tube Q1 is turned off and the second switch tube Q2 is turned on, and keeping the rest of the switch tubes in an off state, the voltage of the first electrode relative to the second electrode is 0, then, the fourth switch tube Q4 is turned off, and the second switch tube Q2 and the third switch tube Q3 are turned on continuously, and keeping the rest of the switch tubes in an off state, the voltage of the first electrode relative to the second electrode is-HV, then, the fourth switch tube Q4 is turned on, the second switch tube Q2 is turned on continuously, and the other switch tubes are kept in the off state, the voltage of the first electrode relative to the second electrode is 0, by so doing, a pulse voltage waveform as shown in fig. 3(c) can be obtained.
In practical applications, the control circuit 150 can flexibly control different switching tubes as required to obtain a suitable pulse voltage waveform, and is not limited herein. It should be noted that, when the first electrode is used as the reference electrode, the generation process of the pulse voltage waveform may be referred to, and detailed steps are not described again.
In some embodiments, referring to fig. 4, the first transmitting circuit 110 further includes a fifth switch Q5, a first terminal of the fifth switch Q5 is connected to the first node M, a second terminal of the fifth switch Q5 is connected to the high voltage negative-HV, and a control terminal of the fifth switch Q5 is connected to the control circuit 150; the second transmitting circuit 120 further includes a sixth switch Q6, a first terminal of the sixth switch Q6 is connected to the second node N, a second terminal of the sixth switch Q6 is connected to the high voltage negative-HV, and a control terminal of the sixth switch Q6 is connected to the control circuit 150.
Specifically, as shown in fig. 4, the control circuit 150 is respectively connected to the first switch tube Q1, the second switch tube Q2, the fifth switch tube Q5 and the first switch circuit 130 in the first transmitting circuit 110, and the control circuit 150 can control any first switch in the first switch circuit 130 to be turned on or off to make any first electrode corresponding to the first switch obtain a voltage. When the control circuit 150 controls the conduction of the first switch tube Q1 through the control end of the first switch tube Q1, any first electrode which is switched on is directly connected with the high-voltage positive electrode + HV through the first switch tube Q1 so as to obtain an absolute positive high voltage; when the control circuit 150 controls the second switching tube Q2 to be conducted through the control end of the second switching tube Q2, any first electrode which is switched on is directly connected with the high-voltage ground GND through the second switching tube Q2 so as to obtain an absolute zero voltage; when the control circuit 150 controls the fifth switching tube Q5 to be turned on through the control terminal of the fifth switching tube Q5, any first electrode that is turned on is directly connected to the high voltage negative electrode-HV through the fifth switching tube Q5 to obtain an absolute negative high voltage.
Further, the control circuit 150 is respectively connected to the third switching tube Q3, the fourth switching tube Q4, the sixth switching tube Q6 and the second switching circuit 140 in the second transmitting circuit 120, and the control circuit 150 can control any second switch in the second switching circuit 140 to be turned on or off to make any second electrode corresponding to the second switch obtain a voltage. When the control circuit 150 controls the third switching tube Q3 to be conducted through the control end of the third switching tube Q3, any second electrode which is switched on is directly connected with the high-voltage positive electrode + HV through the third switching tube Q3 so as to obtain absolute positive high voltage; when the control circuit 130 controls the fourth switching tube Q4 to be turned on through the control end of the fourth switching tube Q4, any second electrode which is turned on is directly connected with the high-voltage ground GND through the fourth switching tube Q4 so as to obtain an absolute zero voltage; when the control circuit 150 controls the sixth switching tube Q6 to be turned on through the control terminal of the sixth switching tube Q6, any second electrode that is turned on is directly connected to the high voltage negative electrode-HV through the sixth switching tube Q6 to obtain an absolute negative high voltage.
In some embodiments, when the second electrode is a reference electrode, wherein when the first switching tube Q1 and the fourth switching tube Q4 are in a conducting state, a positive high voltage with the second electrode as the reference electrode is formed between the first electrode and the second electrode; when the fifth switching tube Q5 and the fourth switching tube Q4 are in a conducting state, a negative high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode; when the second switch tube Q2 and the fourth switch tube Q4 are in a conducting state, a zero voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode; when the first switch tube Q1 and the sixth switch tube Q6 are in a conducting state, a high voltage which is twice as high as that of the second electrode serving as a reference electrode is formed between the first electrode and the second electrode.
Further, when the first electrode is a reference electrode, wherein when the third switching tube Q3 and the second switching tube Q2 are in a conducting state, a positive high voltage with the first electrode as the reference electrode is formed between the first electrode and the second electrode; when the sixth switching tube Q6 and the second switching tube Q2 are in a conducting state, a negative high voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the fourth switching tube Q4 and the second switching tube Q2 are in a conducting state, a zero voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode; when the third switching tube Q3 and the fifth switching tube Q5 are in a conducting state, a high voltage which is twice as high as the reference electrode is formed between the first electrode and the second electrode.
As shown in fig. 4, the control circuit 150 may control the first transmitting circuit 110 and the second transmitting circuit 120 to form a positive high voltage, a negative high voltage, a zero voltage, and a double high voltage between any of the first electrodes and the second electrode.
For example, first, with an arbitrarily turned-on second electrode as a reference electrode, the control circuit 150 may control the first switching tube Q1 and the fourth switching tube Q4 to be in an on state, and control the remaining switching tubes to be in an off state, where a voltage of any turned-on first electrode with respect to any turned-on second electrode is + HV, and a positive high voltage + HV is formed between any turned-on first electrode and any turned-on second electrode, and the voltage is also an absolute positive high voltage; the control circuit 150 can control the fifth switching tube Q5 and the fourth switching tube Q4 to be in a conducting state, and control the other switching tubes to be in a disconnected state, at this time, the voltage of any first electrode which is switched on relative to any second electrode which is switched on is-HV, and a negative high voltage-HV is formed between any first electrode which is switched on and any second electrode which is switched on, and the voltage is also an absolute negative high voltage; the control circuit 150 can control the second switching tube Q2 and the fourth switching tube Q4 to be in a conducting state, and control the other switching tubes to be in a disconnecting state, at this time, the voltage of any first electrode which is switched on relative to any second electrode which is switched on is 0, and zero voltage is formed between any first electrode which is switched on and any second electrode which is switched on, and the voltage is also absolute zero voltage; the control circuit 150 can control the first switch tube Q1 and the sixth switch tube Q6 to be in a conducting state, and control the other switch tubes to be in an off state, wherein the voltage of any first electrode which is turned on relative to any second electrode which is turned on is +2HV, and a double high voltage +2HV is formed between any first electrode which is turned on and any second electrode which is turned on.
Similarly, with any turned-on first electrode as a reference electrode, the control circuit 150 may control the third switching tube Q3 and the second switching tube Q2 to be in a conducting state, and control the remaining switching tubes to be in an off state, where a voltage of any turned-on second electrode with respect to any turned-on first electrode is + HV, and a positive high voltage + HV is formed between any turned-on first electrode and any turned-on second electrode, and the voltage is also an absolute positive high voltage; the control circuit 150 can control the sixth switching tube Q6 and the second switching tube Q2 to be in a conducting state, and control the other switching tubes to be in a disconnected state, at this time, the voltage of any connected second electrode relative to any connected first electrode is-HV, and a negative high voltage-HV is formed between any connected first electrode and any connected second electrode, and the voltage is also an absolute negative high voltage; the control circuit 150 can control the fourth switching tube Q4 and the second switching tube Q2 to be in a conducting state, and control the other switching tubes to be in a disconnecting state, at this time, the voltage of any connected second electrode is 0 relative to the voltage of any connected first electrode, and zero voltage is formed between any connected first electrode and any connected second electrode, and the voltage is also absolute zero voltage; the control circuit 150 can control the third switch tube Q3 and the fifth switch tube Q5 to be in a conducting state, and control the other switch tubes to be in an off state, wherein the voltage of any second electrode which is switched on relative to any first electrode which is switched on is +2HV, and a double high voltage +2HV is formed between any first electrode which is switched on and any second electrode which is switched on.
Further, based on the capability of forming a positive high voltage, a negative high voltage, a zero voltage and a double high voltage between any first electrode and any second electrode, in practical applications, the control circuit 150 can flexibly control the first transmitting circuit 110 and the second transmitting circuit 120 according to requirements to form different pulse voltage waveforms, for example, a plurality of different pulse voltage waveforms as shown in fig. 5 can be formed.
Specifically, as shown in fig. 4-5, when the second electrode is used as the reference electrode, and the fourth switching tube Q4 is in the on state, and when the first switching tube Q1 is turned on and the remaining switching tubes are turned off, the voltage of the first electrode with respect to the second electrode is + HV, and when the first switching tube Q1 is turned off, the second switching tube Q2 is turned on, and the remaining switching tubes are kept in the off state, the voltage of the first electrode with respect to the second electrode is 0, and the control circuit 150 controls the on and off of the first switching tube Q1 and the second switching tube Q2 in a cyclic manner, so that the pulse voltage waveform shown in fig. 5(a) can be obtained.
When the fourth switching tube Q4 is in a conducting state, if the fifth switching tube Q5 is turned on and the other switching tubes are turned off, the voltage of the first electrode relative to the second electrode is-HV, and when the fifth switching tube Q5 is turned off, the second switching tube Q2 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode relative to the second electrode is 0, and the on/off of the fifth switching tube Q5 and the second switching tube Q2 is cyclically controlled by the control circuit 150, so that the pulse voltage waveform shown in fig. 5(b) can be obtained.
When the sixth switching tube Q6 is in a conducting state, if the first switching tube Q1 is turned on and the other switching tubes are turned off, the voltage of the first electrode with respect to the second electrode is +2HV, and when the first switching tube Q1 is turned off, the fifth switching tube Q5 is turned on and the other switching tubes are kept in a turned-off state, the voltage of the first electrode with respect to the second electrode is 0, and the control circuit 150 controls the on/off of the first switching tube Q1 and the fifth switching tube Q5 in a circulating manner, so that a pulse voltage waveform as shown in fig. 5(c) can be obtained.
When the fourth switching tube Q4 is in a conducting state, if the first switching tube Q1 is turned on and the other switching tubes are turned off, the voltage of the first electrode with respect to the second electrode is + HV, and when the first switching tube Q1 is turned off, the second switching tube Q2 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode with respect to the second electrode is 0, and then when the second switching tube Q2 is turned off, the fifth switching tube Q5 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode with respect to the second electrode is-HV, and the on/off of the first switching tube Q1, the second switching tube Q2 and the fifth switching tube Q5 is cyclically controlled in sequence by the control circuit 150, so that the pulse voltage waveform shown in fig. 5(d) can be obtained.
When the fourth switching tube Q4 is in a conducting state, if the first switching tube Q1 is turned on and the other switching tubes are turned off, the voltage of the first electrode with respect to the second electrode is + HV, and when the first switching tube Q1 is turned off, the fifth switching tube Q5 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode with respect to the second electrode is-HV, and then when the fifth switching tube Q5 is turned off, the second switching tube Q2 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode with respect to the second electrode is 0, and the on/off of the first switching tube Q1, the fifth switching tube Q5 and the second switching tube Q2 are cyclically controlled in sequence by the control circuit 150, so that the pulse voltage waveform shown in fig. 5(e) can be obtained.
When the fourth switching tube Q4 is in a conducting state, if the fifth switching tube Q5 is turned on and the other switching tubes are turned off, the voltage of the first electrode with respect to the second electrode is-HV, and when the fifth switching tube Q5 is turned off, the first switching tube Q1 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode with respect to the second electrode is + HV, and then when the first switching tube Q1 is turned off, the second switching tube Q2 is turned on and the other switching tubes are kept in a disconnected state, the voltage of the first electrode with respect to the second electrode is 0, and the on/off of the fifth switching tube Q5, the first switching tube Q1 and the second switching tube Q2 are cyclically controlled in sequence by the control circuit 150, so that the pulse voltage waveform shown in fig. 5(f) can be obtained.
In practical applications, the control circuit 150 can flexibly control different switching tubes as required to obtain a suitable pulse voltage waveform, for example, when a pulse voltage needs to be increased in the process of treating arrhythmia, the control circuit 150 can control the corresponding switching tubes to adjust the voltage pulse waveform shown in fig. 5(a) to the voltage pulse waveform shown in fig. 5(c), so that the voltage pulse can be adjusted at any time, and the flexibility of controlling and adjusting the pulse voltage is improved.
It should be noted that when the first electrode is used as the reference electrode, the pulse voltage shown in fig. 5 can be obtained by controlling the corresponding third switching tube Q3, fourth switching tube Q4 and sixth switching tube Q6 in the second transmitting circuit 120, and detailed steps are not repeated. And the foregoing is illustrative only and is not to be taken as a specific limitation of the present application.
It should be noted that the first to sixth switching tubes Q1 to Q6 are ideal switching models, and in practical applications, part or all of the first to sixth switching tubes Q1 to Q6 may be implemented by one or more non-ideal switching tubes and some auxiliary components to implement the functions of an ideal switching model, and all of these variations or alternatives are within the scope of the present application, and are not limited herein; the first switch and the second switch may be relays, and the like, and are not limited herein.
In some embodiments, referring to fig. 6, the first to sixth switching tubes Q1 to Q6 have the same structure, and each of them is composed of a plurality of reversely connected switching tubes. Here, two reversely connected switching tubes are taken as an example, and the specific working process refers to the foregoing description, which is not described herein again.
In some embodiments, as shown in fig. 4, the first transmitting circuit 110 further includes a first resistor R1 and a second resistor R2, the first resistor R1 is connected in series between the high voltage positive electrode + HV and the first end of the first switch tube Q1, and the second resistor R2 is connected in series between the high voltage negative electrode-HV and the second end of the fifth switch tube Q5; the second transmitting circuit 120 further includes a third resistor R3 and a fourth resistor R4, the third resistor R3 is connected in series between the high voltage positive electrode + HV and the first end of the third switch tube Q3, and the fourth resistor R4 is connected in series between the high voltage negative electrode-HV and the second end of the sixth switch tube Q6.
It should be noted that the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R4 are current-limiting resistors or current-surge-preventing resistors, and are used to reduce or prevent transient large current and circuit oscillation caused by parasitic inductance or parasitic capacitance when the system discharges.
In summary, the first transmitting circuit is connected to the plurality of first electrodes through the first switch circuit, the second transmitting circuit is connected to the plurality of second electrodes through the second switch circuit, and the control circuit controls the first transmitting circuit, the second transmitting circuit, the first switch circuit, and the second switch circuit, respectively, so as to form a positive high voltage, a negative high voltage, a zero voltage, or a double high voltage between any first electrode and any second electrode. Therefore, by controlling the on-off between the transmitting circuit and the transmitting electrode, the flexible adjustment of the pulse voltage between any two transmitting electrodes is realized, the treatment requirements in various pulsed electric field ablation operations are met, the application prospect of the pulsed electric field ablation technology on arrhythmia treatment is improved to a great extent, the on-off between the transmitting circuit and the transmitting electrode is realized by adopting the switch circuit, the use amount of components can be reduced, the cost is reduced, and the reliability is improved.
Fig. 7 is a schematic structural view of an ablation instrument according to an embodiment of the present invention, and referring to fig. 7, the ablation instrument 1000 includes the high voltage transmitting circuit 100 for a catheter and the catheter 200 described above.
According to the ablation tool provided by the embodiment of the invention, through the accurate control of the pulse voltage of the catheter and the control of the on-off between the transmitting circuit and the transmitting electrode, the flexible adjustment of the pulse voltage between any two transmitting electrodes is realized, the treatment requirements in various pulsed electric field ablation operations are met, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is greatly improved.
It should be noted that the logic and/or steps represented in the flowcharts or otherwise described herein, such as an ordered listing of executable instructions that can be considered to implement logical functions, can be embodied in any computer-readable medium for use by or in connection with an instruction execution system, apparatus, or device, such as a computer-based system, processor-containing system, or other system that can fetch the instructions from the instruction execution system, apparatus, or device and execute the instructions. For the purposes of this description, a "computer-readable medium" can be any means that can contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device. More specific examples (a non-exhaustive list) of the computer-readable medium would include the following: an electrical connection (electronic device) having one or more wires, a portable computer diskette (magnetic device), a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber device, and a portable compact disc read-only memory (CDROM). Additionally, the computer-readable medium could even be paper or another suitable medium upon which the program is printed, as the program can be electronically captured, via for instance optical scanning of the paper or other medium, then compiled, interpreted or otherwise processed in a suitable manner if necessary, and then stored in a computer memory.
It should be understood that portions of the present invention may be implemented in hardware, software, firmware, or a combination thereof. In the above embodiments, the various steps or methods may be implemented in software or firmware stored in memory and executed by a suitable instruction execution system. For example, if implemented in hardware, as in another embodiment, any one or combination of the following techniques, which are known in the art, may be used: a discrete logic circuit having a logic gate circuit for implementing a logic function on a data signal, an application specific integrated circuit having a suitable combinational logic gate circuit, a Programmable Gate Array (PGA), a Field Programmable Gate Array (FPGA), an MCU, a DSP, and the like.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art within the scope of the present invention.
Claims (12)
1. A high voltage transmitting circuit for a catheter, wherein a plurality of first electrodes and a plurality of second electrodes are disposed on the catheter, the high voltage transmitting circuit comprising: a first transmitting circuit, a second transmitting circuit, a first switching circuit, a second switching circuit, and a control circuit,
the first transmitting circuit is connected with the plurality of first electrodes through the first switching circuit;
the second transmitting circuit is connected with the plurality of second electrodes through the second switching circuit;
the control circuit is respectively connected with the first transmitting circuit, the second transmitting circuit, the first switch circuit and the second switch circuit and is used for controlling the first transmitting circuit, the second transmitting circuit, the first switch circuit and the second switch circuit so as to form positive high voltage, negative high voltage, zero voltage or double high voltage between any first electrode and any second electrode.
2. The high voltage transmit circuit for a catheter of claim 1, wherein the first transmit circuit comprises: the first end of the first switch tube is connected with the high-voltage positive electrode, the second end of the first switch tube is connected with the first end of the second switch tube and is provided with a first node, the second end of the second switch tube is connected with a high-voltage ground, the first node is connected with the first electrodes through the first switch circuit, and the control end of the first switch tube and the control end of the second switch tube are respectively connected with the control circuit.
3. The high voltage transmit circuit for a catheter of claim 2, wherein the second transmit circuit comprises: third switch tube and fourth switch tube, wherein, the first end of third switch tube with the high-pressure positive pole links to each other, the second end of third switch tube with the first end of fourth switch tube links to each other and has the second node, the second end of fourth switch tube with link to each other with high pressure, the second node passes through second switch circuit with a plurality of second electrodes link to each other, the control end of third switch tube with the control end of fourth switch tube respectively with control circuit links to each other.
4. The high voltage transmit circuit for a catheter of claim 3, wherein when the second electrode is a reference electrode, wherein,
when the first switching tube and the fourth switching tube are both in a conducting state, a positive high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode;
when the second switching tube and the third switching tube are both in a conducting state, a negative high voltage taking the second electrode as a reference electrode is formed between the first electrode and the second electrode;
when the second switching tube and the fourth switching tube are both in a conducting state, a zero voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode.
5. The high voltage transmit circuit for a catheter of claim 3, wherein when the first electrode is a reference electrode, wherein,
when the third switching tube and the second switching tube are both in a conducting state, a positive high voltage taking the first electrode as a reference electrode is formed between the first electrode and the second electrode;
when the fourth switching tube and the first switching tube are both in a conducting state, a negative high voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode;
when the fourth switching tube and the second switching tube are both in a conducting state, zero voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode.
6. The high voltage transmit circuit for a conduit of claim 3,
the first transmitting circuit further comprises a fifth switching tube, a first end of the fifth switching tube is connected with the first node, a second end of the fifth switching tube is connected with a high-voltage cathode, and a control end of the fifth switching tube is connected with the control circuit;
the second transmitting circuit further comprises a sixth switching tube, the first end of the sixth switching tube is connected with the second node, the second end of the sixth switching tube is connected with the high-voltage negative electrode, and the control end of the sixth switching tube is connected with the control circuit.
7. The high voltage transmit circuit for a catheter of claim 6, wherein when the second electrode is a reference electrode, wherein,
when the first switching tube and the fourth switching tube are in a conducting state, a positive high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode;
when the fifth switching tube and the fourth switching tube are in a conducting state, a negative high voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode;
when the second switching tube and the fourth switching tube are in a conducting state, a zero voltage with the second electrode as a reference electrode is formed between the first electrode and the second electrode;
when the first switching tube and the sixth switching tube are in a conducting state, a high voltage which is multiplied by the second electrode as a reference electrode is formed between the first electrode and the second electrode.
8. The high voltage transmit circuit for a catheter of claim 6, wherein when the first electrode is a reference electrode, wherein,
when the third switching tube and the second switching tube are in a conducting state, a positive high voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode;
when the sixth switching tube and the second switching tube are in a conducting state, a negative high voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode;
when the fourth switching tube and the second switching tube are in a conducting state, a zero voltage with the first electrode as a reference electrode is formed between the first electrode and the second electrode;
when the third switching tube and the fifth switching tube are in a conducting state, a high voltage which is multiplied by the first electrode as a reference electrode is formed between the first electrode and the second electrode.
9. The high voltage transmitting circuit for the conduit according to claim 6, wherein the first switch tube to the sixth switch tube have the same structure and are each composed of a plurality of switch tubes connected in opposite directions.
10. The high voltage transmit circuit for a conduit of claim 6,
the first transmitting circuit further comprises a first resistor and a second resistor, the first resistor is connected in series between the high-voltage anode and the first end of the first switching tube, and the second resistor is connected in series between the high-voltage cathode and the second end of the fifth switching tube;
the second transmitting circuit further comprises a third resistor and a fourth resistor, the third resistor is connected in series between the high-voltage positive electrode and the first end of the third switching tube, and the fourth resistor is connected in series between the high-voltage negative electrode and the second end of the sixth switching tube.
11. The high voltage transmit circuit for a catheter of any of claims 1-10,
the first switch circuit comprises a plurality of first switches, the first switches correspond to the first electrodes one by one, and the first switches are connected between the first nodes and the corresponding first electrodes in series;
the second switch circuit comprises a plurality of second switches, the second switches correspond to the second electrodes one by one, and the second switches are connected in series between the second nodes and the corresponding second electrodes.
12. An ablation instrument comprising a catheter and a high voltage firing circuit for a catheter according to any one of claims 1 to 11.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110875452.4A CN113648045A (en) | 2021-07-30 | 2021-07-30 | High-voltage transmitting circuit for catheter and ablation tool |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110875452.4A CN113648045A (en) | 2021-07-30 | 2021-07-30 | High-voltage transmitting circuit for catheter and ablation tool |
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| Publication Number | Publication Date |
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| CN113648045A true CN113648045A (en) | 2021-11-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110875452.4A Withdrawn CN113648045A (en) | 2021-07-30 | 2021-07-30 | High-voltage transmitting circuit for catheter and ablation tool |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114711958A (en) * | 2022-03-16 | 2022-07-08 | 苏州艾科脉医疗技术有限公司 | Multipolar ablation device for pulsed electric field |
-
2021
- 2021-07-30 CN CN202110875452.4A patent/CN113648045A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114711958A (en) * | 2022-03-16 | 2022-07-08 | 苏州艾科脉医疗技术有限公司 | Multipolar ablation device for pulsed electric field |
| WO2023173647A1 (en) * | 2022-03-16 | 2023-09-21 | 苏州艾科脉医疗技术有限公司 | Pulsed electric field multi-electrode ablation apparatus |
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