CN217940091U

CN217940091U - High-efficient wet process pelletization device that mixes of acyclovir piece

Info

Publication number: CN217940091U
Application number: CN202222004842.7U
Authority: CN
Inventors: 王国军; 刘毅; 郭景旗; 李志丹; 贾徵; 杨次明
Original assignee: Hubei Keyi Pharmaceutic Co ltd
Current assignee: Hubei Keyi Pharmaceutic Co ltd
Priority date: 2022-08-01
Filing date: 2022-08-01
Publication date: 2022-12-02
Anticipated expiration: 2032-08-01

Abstract

The utility model belongs to the technical field of the pelletization device, especially, be a high-efficient wet process pelletization device that mixes of acyclovir piece, the load simulator comprises a case, the utility model discloses an agitating unit who is equipped with, when the operative installations preparation acyclovir piece, it carries out the high-speed revolution to drive big band pulley through power device, big band pulley then can drive stirring spindle rotation, stirring spindle's rotation then drives six mixed blades and rotates the medicine to mixing barrel bottom in the inside bottom of compounding section of thick bamboo and stir the mixture, fixed connection is also rotatory simultaneously at stirring spindle upper end connecting rod simultaneously, the rotation of connecting rod then drives four first stirring vane and four second stirring vane of fixed connection on the connecting rod and rotates, stir the medicine inside the compounding section of thick bamboo, at six mixed blades, under four first stirring vane and four second stirring vane's the co-rotation effect, make the inside medicine of compounding section of thick bamboo mix more high-efficiently, make the quality of medicine obtain promoting.

Description

High-efficient wet process pelletization device that mixes of acyclovir piece

Technical Field

The utility model belongs to the technical field of the pelletization device, concretely relates to high-efficient wet process pelletization device that mixes of acyclovir piece.

Background

With the improvement of medical level and the development of science and technology, more and more drugs for treating different diseases are manufactured, wherein acyclovir tablets are a synthetic purine nucleoside analogue, are mainly used for various infections caused by herpes simplex virus, can be used for HSV infection of primary or recurrent skin, mucous membranes, external genital organs and immunodeficiency patients, are the first choice drugs for treating HSV encephalitis, and can also be used for herpes zoster, EB virus and immunodeficiency patients complicated with varicella and other infections.

At present, adopt the in-process that wet granulation device prepared to acyclovir piece in drug manufacturing, the single mixed blade that uses stirs multiple medicine, the effect of its stirring is relatively poor, it takes a large amount of time to mix, and it is not even enough to mix when stirring direction one side mixes, influence the preparation quality of medicine, and when the medicine of preparing is pelletized to the extrusion shredding through the cutting knife, produce the drug residue easily during the cutting, the tablet particle diameter that cuts out is not completely unanimous, can prepare out the wastrel, cause the waste of medicine, lead to production efficiency lower, it is poor to pelletize the effect.

Based on this, the utility model designs a high-efficient wet process pelletization device that mixes of acyclovir piece to solve above-mentioned problem.

SUMMERY OF THE UTILITY MODEL

For solving the above-mentioned problem that exists among the prior art, the utility model provides a high-efficient wet process pelletization device that mixes of acyclovir piece has the characteristics of mixing high-efficient even and pelletization are effectual.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides an acyclovir piece high-efficient wet process pelletization device that mixes, includes quick-witted case, four bottom stabilizer blades of lower extreme fixedly connected with of machine case, the upper end left side fixedly connected with compounding section of thick bamboo of machine case, the inside bottom movable mounting of compounding section of thick bamboo has agitating unit, agitating unit is including the stirring main shaft, the big band pulley of lower extreme fixedly connected with of stirring main shaft, the stirring main shaft is provided with first connection bearing with compounding section of thick bamboo junction, six hybrid blades of side fixedly connected with of stirring main shaft upper end, stirring main shaft upper end fixedly connected with connecting rod, four first stirring vane of fixedly connected with and four second stirring vane are distinguished to the side of connecting rod, the upper end of connecting rod is provided with the end cover, agitating unit passes through big band pulley and is connected with the power device transmission.

As a preferred technical scheme of the utility model, power device is including positive reverse motor, movable mounting has the transmission shaft in the positive reverse motor, the upper end fixed mounting of transmission shaft has little band pulley, little band pulley carries out the transmission through drive belt and big band pulley and is connected, four supports of side fixedly connected with of positive reverse motor, four fixedly connected with backup pad between the support, positive reverse motor is placed in the backup pad, four the equal fixed connection of support is on the bottom plate of quick-witted incasement portion.

As a preferred technical scheme of the utility model, the left side fixed mounting of compounding section of thick bamboo has pelletization mechanism, be provided with out the grain mouth in the pelletization mechanism, the collecting box has been placed to the below of going out the grain mouth the upper end fixedly connected with electrical system of the right side machine case of compounding section of thick bamboo, electrical system's front is provided with control panel.

As a preferred technical scheme of the utility model, pelletization mechanism includes the shell body, the interior fixedly connected with medicine conveying pipeline of shell body, the inside center department of medicine conveying pipeline is provided with the pivot, fixedly connected with helical blade in the pivot, the right-hand member movable mounting of pivot is in the bearing frame, the bearing frame is through the inside of four fixed plate fixed mounting at medicine conveying pipeline right-hand member.

As a preferred technical scheme of the utility model, the left end fixed mounting of medicine conveying pipeline has the pelletization piece, it extrudes the hole to have seted up a plurality ofly on the pelletization piece, the side fixed mounting of the left end pivot of pelletization piece has the cutting knife, the left end fixedly connected with dust proof box of shell body, dust proof box lower extreme is provided with out the grain mouth, the bearing is connected to fixedly connected with second in the left side wall of dust proof box, the pivot passes the second and connects the bearing and be connected with the transmission motor transmission, transmission motor fixed connection is on the left side wall of dust proof box.

As a preferred technical scheme of the utility model, mixing barrel includes the barrel, the upper end of barrel is provided with material mouth and adhesive and adds the mouth, the barrel is provided with the discharge gate with pelletization mechanism intercommunication department.

As an optimized technical scheme of the utility model, the bottom of barrel is through four stand fixed connection in the upper end of quick-witted case.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the utility model discloses when using, through the agitating unit who is equipped with, when the operative installations prepares acyclovir piece, drive big band pulley through power device and carry out the fast revolution, big band pulley then can drive the rotation of stirring main shaft, the rotation of stirring main shaft then drives six mixing blades and rotates the medicine of mixing barrel bottom in the bottom of mixing barrel inside and stir the mixture, fixed connection is simultaneously also rotated at stirring main shaft upper end connecting rod simultaneously, the rotation of connecting rod then drives four first stirring vane and four second stirring vane of fixed connection on the connecting rod and rotates, stir the medicine inside the mixing barrel, under the common rotating action of six mixing blade, four first stirring vane and four second stirring vane, make the medicine mix inside the mixing barrel more high-efficiently, make the quality of medicine obtain promoting;

2. the utility model discloses when using, through the power device who is equipped with, positive reverse motor can drive the transmission shaft and carry out corotation or reversal, the corotation or the reversal of transmission shaft can drive little band pulley and carry out corotation or reversal, the corotation of little band pulley or the transmission effect of reversal through the drive belt can drive agitating unit and carry out corotation or reversal, agitating unit's corotation or reversal then make and carry out two-way stirring to the inside medicine of a compounding section of thick bamboo, it is more even to make the medicine mix under the combined action of power device and a compounding section of thick bamboo, the efficiency of mixing is higher, speed is faster.

3. The utility model discloses when using, through the pelletization mechanism that is equipped with, after the medicine mixes the completion, open the discharge gate, the medicine that will mix under the rotatory effect of agitating unit passes through the discharge gate and carries to the defeated medicine pipeline in, drive motor drives the epaxial helical blade of pivot simultaneously and rotates, carry the medicine in the defeated medicine pipeline and carry to the pelletization piece under helical blade's rotation, the extrusion effect of carrying mixed medicine through helical blade makes the mixed medicine extrusion through the extrusion hole of seting up on the pelletization piece, the mixed medicine through extruding the hole can be cut off by the cutting knife, pelletize mixed medicine, the medicine grain size that makes the preparation out is even, when improving the pelletization effect, also make the production efficiency of medicine obtain improving.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings:

fig. 1 is a schematic view of the overall front structure of the present invention;

fig. 2 is a schematic view of the overall back structure of the present invention;

FIG. 3 is a schematic structural view of the mixing and granulating apparatus of the present invention;

FIG. 4 is a schematic sectional view of the mixing barrel of the present invention;

FIG. 5 is a schematic structural view of the stirring device of the present invention;

fig. 6 is a schematic sectional structure view of the granulating mechanism of the present invention;

fig. 7 is a schematic side sectional structure view of the granulating mechanism of the present invention.

In the figure: 1. a chassis; 2. a bottom foot; 3. an electronic control system; 301. a control panel; 4. a collection box; 5. a mixing cylinder; 501. a barrel; 502. a material port; 503. an adhesive addition port; 504. a discharge port; 6. a stirring device; 601. a stirring main shaft; 602. a large belt pulley; 603. a first connecting bearing; 604. a mixing blade; 605. a connecting rod; 606. a first stirring blade; 607. a second stirring blade; 608. an end cap; 7. a power plant; 701. a forward and reverse rotation motor; 702. a drive shaft; 703. a small belt pulley; 704. a transmission belt; 705. a support; 706. a support plate; 8. a granulation mechanism; 801. an outer housing; 802. a drug delivery conduit; 803. a rotating shaft; 804. a helical blade; 805. a bearing seat; 806. a fixing plate; 807. granulating; 808. a cutting knife; 809. a dust-proof box; 8010. a second connecting bearing; 8011. a drive motor; 9. and a grain outlet.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.

Examples

Referring to fig. 1-7, the present invention provides the following technical solutions: the utility model provides an acyclovir piece high-efficient wet process pelletization device that mixes, the load simulator comprises a case 1, four bottom stabilizer blades 2 of lower extreme fixedly connected with of machine case 1, upper end left side fixedly connected with mixing barrel 5 of machine case 1, the inside bottom movable mounting of mixing barrel 5 has agitating unit 6, agitating unit 6 includes stirring main shaft 601, the big band pulley 602 of lower extreme fixedly connected with of stirring main shaft 601, stirring main shaft 601 is provided with first connection bearing 603 with mixing barrel 5 junction, six mixed blades 604 of side fixedly connected with of stirring main shaft 601 upper end, stirring main shaft 601 upper end fixedly connected with connecting rod 605, four first stirring vane 606 of fixedly connected with and four second stirring vane 607 respectively of side of connecting rod 605, the upper end of connecting rod 605 is provided with end cover 608, agitating unit 6 is connected with the transmission of power device 7 through big band pulley 602.

Referring to fig. 5, in a specific use, while the power device 7 drives the large belt wheel 602 to rotate, the large belt wheel 602 drives the stirring main shaft 601 and the six mixing blades 604, the four first mixing blades 606 and the four second mixing blades 607 fixedly connected to the connecting rod 605 to rotate synchronously, so as to mix the medicines in the mixing cylinder 5 quickly and uniformly, thereby improving mixing efficiency and mixing effect.

The power device 7 comprises a forward and reverse rotating motor 701, a transmission shaft 702 is movably mounted in the forward and reverse rotating motor 701, a small belt wheel 703 is fixedly mounted at the upper end of the transmission shaft 702, the small belt wheel 703 is in transmission connection with a large belt wheel 602 through a transmission belt 704, four supports 705 are fixedly connected to the side faces of the forward and reverse rotating motor 701, a support plate 706 is fixedly connected among the four supports 705, the forward and reverse rotating motor 701 is placed on the support plate 706, and the four supports 705 are all fixedly connected to a bottom plate in the case 1.

Referring to fig. 4, in a specific use, the forward and reverse rotating motor 701 drives the small belt pulley 703 on the transmission shaft 702 to rotate, and the small belt pulley 703 is in transmission connection with the large belt pulley 602 through the transmission belt 704, so as to drive the stirring device 6 to rotate, so that the stirring device 6 can rotate forward and backward, and the mixing effect of the medicines in the cylinder 501 is better.

The left side fixed mounting of compounding section of thick bamboo 5 has pelletization mechanism 8, is provided with out grain mouth 9 on the pelletization mechanism 8, and the upper end fixedly connected with electrical system 3 of the right side machine case 1 of collecting box 4 compounding section of thick bamboo 5 has been placed to the below of out grain mouth 9, and electrical system 3's front is provided with control panel 301.

Pelletization mechanism 8 includes shell body 801, the interior fixedly connected with medicine pipeline 802 of shell body 801, and medicine pipeline 802 inside center department is provided with pivot 803, fixedly connected with helical blade 804 on the pivot 803, and the right-hand member movable mounting of pivot 803 is in bearing frame 805, and bearing frame 805 is through four fixed plates 806 fixed mounting in the inside of medicine pipeline 802 right-hand member.

The left end fixed mounting of medicine conveying pipeline 802 has pelletization piece 807, has seted up a plurality of extrusion holes on the pelletization piece 807, and the side fixed mounting of the left end pivot 803 of pelletization piece 807 has cutting knife 808, and the left end fixed connection of shell body 801 has dust box 809, and dust box 809 lower extreme is provided with out grain mouth 9, and fixedly connected with second connection bearing 8010 in dust box 809's the left side wall, pivot 803 pass the second and connect bearing 8010 and be connected with driving motor 8011 transmission, driving motor 8011 fixed connection is on dust box 809's the left side wall.

Referring to fig. 6 and 7, in a specific use, the rotating shaft 803 can be driven to rotate under the action of the driving motor 8011, the rotating shaft 803 can drive the helical blade 804 and the cutting knife 808 which are fixedly connected to the rotating shaft 803 to rotate, the helical blade 804 can be rotated to convey mixed drugs in the drug delivery pipeline 802, and the cutting knife 808 can be rotated to cut the drugs extruded from the granulation sheets 807, so as to achieve the purpose of granulating the drugs.

The mixing barrel 5 comprises a barrel body 501, a material port 502 and an adhesive adding port 503 are arranged at the upper end of the barrel body 501, and a material outlet 504 is arranged at the communication position of the barrel body 501 and the granulating mechanism 8.

Referring to fig. 4, in a specific use, a material port 502 is used for conveniently adding a medicine into the cylinder 501, and an adhesive adding port 503 is used for conveniently adding an adhesive into the cylinder 501.

The bottom of the cylinder 501 is fixedly connected to the upper end of the case 1 through four columns.

The utility model discloses a theory of operation and use flow: in the using process of the utility model, firstly, the medicine to be mixed is added into the cylinder 501 through the material port 502 at the upper end of the cylinder 501, then the forward and reverse rotation motor 701 is controlled to be started through the control panel 301, the forward and reverse rotation motor 701 drives the transmission shaft 702 to rotate, the rotation of the transmission shaft 702 enables the small belt wheel 703 to rotate, the rotation of the small belt wheel 703 drives the large belt wheel 602 to rotate through the transmission of the transmission belt 704, the rotation of the large belt wheel 602 drives the stirring main shaft 601 to rotate, the rotation of the stirring main shaft 601 enables the mixing blade 604 and the connecting rod 605 which are fixedly connected on the stirring main shaft 601 to rotate, the rotation of the mixing blade 604 can stir the medicine at the bottom of the cylinder 501, the rotation of the connecting rod 605 enables the four first stirring blades 606 and the second stirring blades 607 which are fixedly connected on the connecting rod 605 to rotate, thereby stirring the medicine of the cylinder 501, the adhesive is added into the cylinder 501 through the adhesive adding port 503 while stirring, the forward and reverse rotation of the forward and reverse rotation motor 701 can automatically reverse rotation after a certain time, the forward rotation and reverse rotation of the spiral medicine is enabled to extrude the medicine in the cylinder 501 through the spiral extrusion conveying pipe 804, the spiral tablet 804 which drives the spiral medicine conveying pipe 804 which drives the spiral tablet 804 to extrude the medicine, the medicine to extrude the medicine in the spiral extrusion conveying pipe 804, the spiral extrusion conveying pipe 504, the spiral extrusion conveying pipe 804 which drives the spiral extrusion conveying pipe 804 which extrudes more uniformly, then by the cutting knife 808 of the rotation on the pivot 803 cutting into graininess, the realization is to the pelletization of mixed medicine, makes the medicine grain size of making even, improves the efficiency and the quality of medicine production, and the medicine grain after the cutting is accomplished then drops to collecting box 4 in through a grain mouth 9, collects the medicine grain.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described above, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The utility model provides an acyclovir tablet high-efficient wet process pelletization device that mixes, includes quick-witted case (1), its characterized in that: four bottom stabilizer blades (2) of lower extreme fixedly connected with of quick-witted case (1), the upper end left side fixedly connected with mixing barrel (5) of quick-witted case (1), the inside bottom movable mounting of mixing barrel (5) has agitating unit (6), agitating unit (6) are including stirring main shaft (601), the big band pulley of lower extreme fixedly connected with (602) of stirring main shaft (601), stirring main shaft (601) and mixing barrel (5) junction are provided with first connection bearing (603), six hybrid blades (604) of side fixedly connected with of stirring main shaft (601) upper end, stirring main shaft (601) upper end fixedly connected with connecting rod (605), the side of connecting rod (605) is four first stirring vane (606) of fixedly connected with and four second stirring vane (607) respectively, the upper end of connecting rod (605) is provided with end cover (608), agitating unit (6) are connected with power device (7) transmission through big band pulley (602).

2. The high-efficiency mixing wet granulation device for acyclovir tablets as claimed in claim 1, is characterized in that: the power device (7) comprises a forward and reverse rotating motor (701), a transmission shaft (702) is movably mounted in the forward and reverse rotating motor (701), a small belt wheel (703) is fixedly mounted at the upper end of the transmission shaft (702), and the small belt wheel (703) is in transmission connection with a large belt wheel (602) through a transmission belt (704).

3. The high-efficiency mixing wet granulation device for acyclovir tablets as claimed in claim 2, is characterized in that: the side face of the forward and reverse rotation motor (701) is fixedly connected with four supports (705), a supporting plate (706) is fixedly connected between the four supports (705), the forward and reverse rotation motor (701) is placed on the supporting plate (706), and the four supports (705) are fixedly connected to a bottom plate inside the case (1).

4. The high-efficiency mixing wet granulation device for acyclovir tablets as claimed in claim 1, is characterized in that: the left side fixed mounting of compounding section of thick bamboo (5) has pelletization mechanism (8), be provided with grain outlet (9) on pelletization mechanism (8), collecting box (4) have been placed to the below of grain outlet (9) the upper end fixedly connected with electrical system (3) of right side machine case (1) of compounding section of thick bamboo (5), the front of electrical system (3) is provided with control panel (301).

5. The acyclovir tablet efficient mixing wet granulation device of claim 4, which is characterized in that: pelletization mechanism (8) are including shell body (801), the interior fixedly connected with medicine conveying pipeline (802) of shell body (801), medicine conveying pipeline (802) inside center department is provided with pivot (803), fixedly connected with helical blade (804) on pivot (803).

6. The acyclovir tablet efficient mixing wet granulation device of claim 5, characterized in that: the right end of the rotating shaft (803) is movably arranged in a bearing seat (805), and the bearing seat (805) is fixedly arranged inside the right end of the medicine conveying pipeline (802) through four fixing plates (806).

7. The efficient acyclovir tablet mixing wet granulation device according to claim 6, wherein the efficient acyclovir tablet mixing wet granulation device comprises: the left end fixed mounting of defeated medicine pipeline (802) has pelletization piece (807), a plurality of extrusion holes have been seted up on pelletization piece (807), the side fixed mounting of the left end pivot (803) of pelletization piece (807) has cutting knife (808), the left end fixedly connected with dust proof box (809) of shell body (801), dust proof box (809) lower extreme is provided with grain outlet (9).

8. The efficient acyclovir tablet mixing wet granulation device according to claim 7, wherein the efficient acyclovir tablet mixing wet granulation device comprises: the dust prevention box (809) is characterized in that a second connecting bearing (8010) is fixedly connected to the inner side wall of the left side wall of the dust prevention box (809), the rotating shaft (803) penetrates through the second connecting bearing (8010) to be in transmission connection with a transmission motor (8011), and the transmission motor (8011) is fixedly connected to the left side wall of the dust prevention box (809).

9. The high-efficiency mixing wet granulation device for acyclovir tablets as claimed in claim 1, is characterized in that: the mixing barrel (5) comprises a barrel body (501), a material port (502) and an adhesive adding port (503) are arranged at the upper end of the barrel body (501), and a discharging port (504) is arranged at the communication position of the barrel body (501) and the granulating mechanism (8).

10. The acyclovir tablet high-efficiency mixing wet granulation device of claim 9, which is characterized in that: the bottom of the cylinder (501) is fixedly connected to the upper end of the case (1) through four upright posts.