CN217901657U

CN217901657U - Liquid chromatograph refrigeration type sample inlet disc mechanism

Info

Publication number: CN217901657U
Application number: CN202222066432.5U
Authority: CN
Inventors: 付正建; 杜传红; 熊腾飞; 温兆镇
Original assignee: Wuxi Sanaer Instrument Equipment Manufacturing Co ltd
Current assignee: Wuxi Sanaer Instrument Equipment Manufacturing Co ltd
Priority date: 2022-08-05
Filing date: 2022-08-05
Publication date: 2022-11-25
Anticipated expiration: 2032-08-05

Abstract

The utility model belongs to the technical field of chemical analysis detects, especially, relate to liquid chromatograph refrigeration type advances a set mechanism, including sample dish, low temperature box and heat transfer structure, low temperature box one side is equipped with the socket, and the sample dish inserts the socket and installs in the low temperature box, and the bottom of low temperature box is equipped with heat transfer structure, and heat transfer structure includes heating panel and at least one semiconductor refrigeration piece, and the low temperature box is established in one side subsides of semiconductor refrigeration piece, and the fin is established in another side subsides of semiconductor refrigeration piece. The utility model provides a liquid chromatograph refrigeration type advances appearance dish mechanism through the setting of semiconductor refrigeration piece, can realize cooling down the refrigeration to the low temperature box, looses the heat that the another side produced when semiconductor refrigeration piece is because of the refrigeration through the fin to the realization protects the sample in the sample bottle promptly to the low temperature protection of sample dish, and then avoids sensitive to the temperature, and the unstable sample of normal atmospheric temperature takes place to degrade, and then improves and detect the accuracy.

Description

Liquid chromatograph refrigeration type sample inlet disc mechanism

Technical Field

The utility model belongs to the technical field of chemical analysis detects, especially, relate to liquid chromatograph refrigeration type advances a set mechanism.

Background

The liquid chromatography is an important branch of the chromatography, liquid is taken as a mobile phase, a high-pressure infusion system is adopted, the mobile phase such as single solvents with different polarities or mixed solvents with different proportions, buffer solutions and the like and a sample to be detected are pumped into a chromatographic column filled with a stationary phase, and after components of the sample to be detected are separated in the chromatographic column, the components enter corresponding detectors for detection, so that the qualitative and quantitative analysis of the sample is realized. As a high-precision and fast analysis and separation tool, liquid chromatography has become an increasingly important analysis and preparation means in the aspects of life sciences, pharmaceutical industry, biochemical technology and fine chemical production. The automatic sample injector is an important component of liquid chromatogram, has the function of automatically and accurately injecting a sample with a set volume into a high-pressure system for separation, analysis and detection, and has the advantages of high automation degree and accurate quantification. However, some samples are easily degraded at normal temperature, and are degraded when waiting for sample injection in a sample injector, so that the detection precision is influenced.

SUMMERY OF THE UTILITY MODEL

The not enough to above-mentioned prior art, the utility model provides a liquid chromatograph refrigeration type advances sample dish mechanism, the purpose is in order to solve some samples and easily degrade at normal atmospheric temperature, takes place the degradation when waiting for to advance the appearance in the injector to influence the technical problem of the precision that detects.

The utility model provides a liquid chromatograph refrigeration type advances a set mechanism, concrete technical scheme as follows:

liquid chromatograph refrigeration type advances a kind set mechanism, including sample dish, low temperature box and heat transfer structure, low temperature box one side is equipped with the socket, the sample dish inserts the socket is installed in the low temperature box, the bottom of low temperature box is equipped with heat transfer structure, heat transfer structure includes heating panel and at least one semiconductor refrigeration piece, the one side subsides of semiconductor refrigeration piece are established the low temperature box, another side subsides of semiconductor refrigeration piece are established the fin.

In some embodiments, two layers of heat insulation sheets are arranged between the low-temperature box and the heat dissipation plate, at least one placing groove is formed in each of the two layers of heat insulation sheets corresponding to the semiconductor refrigeration sheets, and the semiconductor refrigeration sheets are embedded in the placing grooves.

In some embodiments, the cryobox includes a heat-conducting bottom plate and three heat-insulating side plates, a cryotank is surrounded by the heat-conducting bottom plate and the three heat-insulating side plates, the sample tray is disposed in the cryotank, and the semiconductor chilling plate is attached to the heat-conducting bottom plate.

Furthermore, the low-temperature box also comprises a plurality of limiting plates, the limiting plates are arranged on the heat-conducting bottom plate and enclose a limiting space in the low-temperature groove, and the limiting space is configured to position the sample plate in the low-temperature groove.

In some embodiments, there are three semiconductor chilling plates, and three semiconductor chilling plates are arranged side by side.

Further, the low temperature box with one side that the socket is relative is equipped with the desicator and has seted up the leakage fluid dram, the desicator is equipped with circulating fan, the leakage fluid dram intercommunication has the cistern.

In some embodiments, a stopper is connected to one side of the sample tray, the stopper is matched with the socket, and the stopper is provided with a pull groove.

The utility model discloses following beneficial effect has: the utility model provides a liquid chromatograph refrigeration type advances appearance dish mechanism through the setting of semiconductor refrigeration piece, can realize cooling down the refrigeration to the low temperature box, looses the heat that the another side produced when semiconductor refrigeration piece is because of the refrigeration through the fin to the realization protects the sample in the sample bottle promptly to the low temperature protection of sample dish, and then avoids sensitive to the temperature, and the unstable sample of normal atmospheric temperature takes place to degrade, and then improves and detect the accuracy.

Drawings

Fig. 1 is a schematic perspective view of a refrigeration-type sampling tray mechanism of a liquid chromatograph provided in embodiment 1 of the present invention;

fig. 2 is a schematic plan structure diagram of a refrigeration-type sample tray mechanism of a liquid chromatograph provided in embodiment 1 of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail with reference to the accompanying drawings 1-2 in conjunction with the following embodiments.

Example 1

The liquid chromatograph refrigeration type advances a set mechanism that this embodiment provided, concrete technical scheme is as follows:

liquid chromatograph refrigeration type advances a kind dish mechanism, including sample dish 1, low temperature box 2 and

heat transfer structure

3, 2 one sides of low temperature box are equipped with socket 41, and sample dish 1 inserts socket 41 and installs in low temperature box 2, and the bottom of low temperature box 2 is equipped with heat transfer structure 3, and heat transfer structure 3 includes heating panel 31 and at least one semiconductor refrigeration piece 32, and low temperature box 2 is established in the one side subsides of semiconductor refrigeration piece 32, and the fin is established in another subsides of semiconductor refrigeration piece 32. The low-temperature box 2 is used for creating a low-temperature environment for the sample box, the semiconductor refrigeration piece 32 achieves the cooling effect through reversely passing current, and the radiating fin dissipates heat generated by the other surface of the semiconductor refrigeration piece 32 during refrigeration.

Specifically, two layers of heat insulation sheets 5 are arranged between the low-temperature box 2 and the heat dissipation plate 31, at least one placing groove 51 is formed in the two layers of heat insulation sheets 5 corresponding to the semiconductor refrigeration sheets 32, and the semiconductor refrigeration sheets 32 are embedded in the placing groove 51. Two-layer heat insulating sheet 5 on the one hand can be so that the bottom surface of low temperature box keeps warm, avoids low temperature box bottom surface and external quick heat exchange, and on the other hand has seted up standing groove 51 and has guaranteed that semiconductor refrigeration piece 32 can realize the contact with low temperature box 2 to reach the effect of conduction. In addition, the two layers of the heat insulating sheet 5 are provided in order to have an air layer between the two layers of the heat insulating sheet 5, thereby enhancing the heat insulating effect.

Specifically, the cryostat 2 comprises a heat-conducting bottom plate 21 and three heat-insulating side plates 22, the heat-conducting bottom plate 21 and the three heat-insulating side plates 22 enclose a low-temperature groove 42, the sample tray 1 is arranged in the low-temperature groove 42, and the semiconductor refrigeration sheet 32 is attached to the heat-conducting bottom plate 21. The low temperature environment of low temperature box 2 mainly carries out the temperature transmission through heat conduction bottom plate 21 and semiconductor refrigeration piece 32 and realizes that three thermal-insulated curb plate 22 is arranged in maintaining the low temperature environment in low temperature box 2 on every side, avoids low-temperature box and external quick heat exchange.

Specifically, the cryostat 2 further includes a plurality of position limiting plates 43, the plurality of position limiting plates 43 are disposed on the heat conducting bottom plate 21 and enclose a position limiting space in the cryogenic tank 42, and the position limiting space is configured to position the sample tray 1 in the cryogenic tank 42. The three limiting plates 43 in this embodiment form two limiting spaces adapted to have two sample trays 1 (sample tray a and sample tray B) inserted together into the cryostat 2.

In this embodiment, three semiconductor chilling plates 32 are provided, and the three semiconductor chilling plates 32 are arranged side by side. Three semiconductor refrigeration pieces 32 are designed side by side to share one heat dissipation plate 31, and the effect of three refrigeration is more excellent.

Specifically, a dryer 61 is disposed on the side of the low-temperature box 2 opposite to the socket 41, and a liquid discharge port 44 is disposed on the side, the dryer 61 is provided with a circulating fan 62, and the liquid discharge port 44 is communicated with a liquid guide groove 63. The semiconductor refrigeration piece 32 close to the dryer 61 is refrigerated, the temperature is set to be 4 ℃ lower than the room temperature or exceeds 4 ℃, the circulating fan 62 is started, the air in the sample injector where the liquid chromatograph refrigeration type sample injection tray mechanism of the embodiment is located is circulated, the water vapor in the air is condensed into small water drops at the dryer 61 and is discharged to the outside through the liquid outlet 44 oil guide tank 63 after being collected, the humidity in the sample injector is reduced, and the pollution of the sample and the damage to other hardware caused by excessive condensate water generated by refrigeration are avoided.

Specifically, one side of the sample plate 1 is connected with a stopper 11, the stopper 11 is matched with the socket 41, and the stopper 11 is provided with a pull groove 12. The stopper 11 is used for stopping the inserting hole 41, and the pull groove 12 is used for facilitating the drawing of the sample plate 1.

To sum up, the utility model provides a liquid chromatograph refrigeration type advances appearance dish mechanism through the setting of semiconductor refrigeration piece 32, can realize cooling down the refrigeration to low temperature box 2, looses the heat that the another side produced when semiconductor refrigeration piece 32 because of the refrigeration through the fin to the realization protects the sample in the sample bottle promptly to the low temperature protection of sample dish 1, and then avoids sensitive to the temperature, and the unstable sample of normal atmospheric temperature takes place to degrade, and then improves and detects the accuracy.

The above-mentioned only the utility model discloses preferred feasible embodiment is not right the utility model discloses a restriction, the utility model discloses also not be limited to the above-mentioned example, technical field's technical personnel the utility model discloses an in the essential scope, change, modification, interpolation or replacement made also should belong to the protection scope of the utility model.

Claims

1. Liquid chromatograph refrigeration type advances a set mechanism, its characterized in that, including sample dish, low temperature box and heat transfer structure, low temperature box one side is equipped with the socket, the sample dish inserts the socket is installed in the low temperature box, the bottom of low temperature box is equipped with the heat transfer structure, the heat transfer structure includes heating panel and at least one semiconductor refrigeration piece, the one side subsides of semiconductor refrigeration piece are established the low temperature box, another face subsides of semiconductor refrigeration piece are established the heating panel.

2. The liquid chromatograph refrigeration type advances a kind dish mechanism of claim 1, characterized in that, be equipped with two-layer heat insulating sheet between low temperature box and the heating panel, two-layer heat insulating sheet corresponds semiconductor refrigeration piece has seted up at least one standing groove, semiconductor refrigeration piece inlays to be established in the standing groove.

3. The liquid chromatograph refrigeration type sample feeding tray mechanism of claim 1, wherein the cryobox comprises a heat conducting bottom plate and three heat insulating side plates, the heat conducting bottom plate and the three heat insulating side plates enclose a cryotrough, the sample tray is arranged in the cryotrough, and the semiconductor refrigeration sheet is attached to the heat conducting bottom plate.

4. The liquid chromatograph refrigeration-based sample tray mechanism of claim 3, wherein the cryostat further comprises a plurality of confinement plates disposed on a thermally conductive floor and enclosing a confinement space in the cryostat, the confinement space configured to position the sample tray in the cryostat.

5. The liquid chromatograph refrigeration type advances a kind dish mechanism of claim 1, characterized in that, the semiconductor refrigeration piece is provided with three, three the semiconductor refrigeration piece sets up side by side.

6. The refrigeration type sample feeding tray mechanism of the liquid chromatograph of claim 5, wherein a dryer is disposed on a side of the low temperature box opposite to the socket and is provided with a liquid discharge port, the dryer is provided with a circulating fan, and the liquid discharge port is communicated with a liquid guide groove.

7. The liquid chromatograph refrigeration type sample feeding disc mechanism of claim 1, wherein a stopper is connected to one side of the sample disc, the stopper is adapted to the socket, and the stopper is provided with a pull groove.