CN217855827U - Can improve nucleic acid extraction efficiency's oscillating structure for nucleic acid extraction appearance - Google Patents
Can improve nucleic acid extraction efficiency's oscillating structure for nucleic acid extraction appearance Download PDFInfo
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- CN217855827U CN217855827U CN202220273560.4U CN202220273560U CN217855827U CN 217855827 U CN217855827 U CN 217855827U CN 202220273560 U CN202220273560 U CN 202220273560U CN 217855827 U CN217855827 U CN 217855827U
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- magnetic rod
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Abstract
The utility model provides a vibrating structure for nucleic acid extractor, which can improve nucleic acid extraction efficiency, comprising a bracket, wherein the bracket is provided with a slide rail, one slide block of the slide rail is provided with a magnetic bar mounting plate, the other slide block of the slide rail is provided with a magnetic bar sleeve mounting plate arranged below the magnetic bar mounting plate, and two opposite side walls of the bracket are respectively provided with a conveying mechanism for driving the magnetic bar sleeve mounting plate and the magnetic bar mounting plate to move up and down to vibrate detection liquid; conveying mechanism includes conveyor motor, and conveyor motor installs inside the support, is provided with the action wheel on conveyor motor's the output shaft, is provided with on the support lateral wall to be located the action wheel with the linking piece of one side, links up the internally mounted of piece and has the rotation post, is provided with on the rotation post from the driving wheel, the action wheel with from being provided with the conveyer belt between the driving wheel, be provided with the connecting block that drive bar magnet cover mounting panel or bar magnet mounting panel removed on the conveyer belt, the utility model discloses rational in infrastructure, stability is high, and extraction efficiency is high, and it is convenient to remove the connection.
Description
Technical Field
The utility model relates to a can improve oscillating structure for nucleic acid extraction appearance of nucleic acid extraction efficiency belongs to oscillating structure technical field for the nucleic acid extraction appearance.
Background
The substance for nucleic acid detection is a nucleic acid of a virus. The nucleic acid detection is to find out whether the respiratory tract specimen, blood or feces of the patient have the nucleic acid of the virus invaded from the outside to determine whether the patient is infected by the new coronavirus. Therefore, once the detection result is positive, the virus in the patient can be proved, and a nucleic acid extractor is needed when the nucleic acid is detected. The nucleic acid extractor is an instrument which automatically finishes the extraction work of sample nucleic acid by using matched nucleic acid extraction reagents and is divided into an automatic liquid workstation and a small automatic nucleic acid extractor according to different sizes of instruments. The extraction principle is divided into an instrument using a centrifugal column method and an instrument using a magnetic bead method.
In the prior art, the extraction method of the nucleic acid extractor adopting the magnetic bead method comprises the following steps: the sample is shaken for about 10 seconds to elute pathogens from the swab into the virus maintenance solution as much as possible, then 200. Mu.L of the sample is pipetted into the sample lysate, and then the sample nucleic acid is extracted by the fully automatic nucleic acid extractor. When the existing oscillation structure for the nucleic acid extraction instrument is used, a vibration motor generally drives a magnetic rod to vibrate sample liquid to be extracted, and the vibration motor drives the magnetic rod to vibrate and simultaneously drives other structures in the instrument to vibrate, so that the other structures of the instrument are easy to loosen, the stability of the oscillation structure of the instrument is low, and the other structures need to be overhauled, maintained and screwed again to be fixed so as not to influence the extraction efficiency of nucleic acid due to faults. In addition, the oscillation mechanism of the existing magnetic bead method nucleic acid extractor cannot control the oscillation frequency, the liquid to be extracted cannot oscillate at a proper oscillation frequency, and the extraction efficiency is low; in addition, the magnetic bar and the magnetic bar of the existing magnetic bead method nucleic acid extractor have low oscillation frequency, which also affects the extraction efficiency, so that an oscillation structure for the nucleic acid extractor, which can improve the nucleic acid extraction efficiency, is urgently needed to solve the problems.
SUMMERY OF THE UTILITY MODEL
Not enough to prior art exists, the utility model aims at providing a can improve oscillating structure for nucleic acid extraction appearance of nucleic acid extraction efficiency to solve the problem that proposes in the above-mentioned background art, the utility model discloses rational in infrastructure, stability is high, and extraction efficiency is high, and it is convenient to remove the connection.
In order to achieve the above purpose, the present invention is realized by the following technical solution: an oscillating structure for a nucleic acid extraction instrument capable of improving nucleic acid extraction efficiency comprises a support, wherein a slide rail is arranged on the support, a magnetic rod mounting plate is arranged on one slide block of the slide rail, a magnetic rod sleeve mounting plate arranged below the magnetic rod mounting plate is arranged on the other slide block of the slide rail, and conveying mechanisms for driving the magnetic rod sleeve mounting plate and the magnetic rod mounting plate to move up and down to vibrate an extract to be extracted are respectively arranged on two opposite side walls of the support;
conveying mechanism includes conveyor motor, conveyor motor installs inside the support, be provided with the action wheel on conveyor motor's the output shaft, be provided with the linking piece that lies in action wheel same one side on the support lateral wall, linking piece internally mounted has the rotation post, be provided with from the driving wheel on the rotation post, the action wheel with from being provided with the conveyer belt between the driving wheel, be provided with the connecting block that drive bar magnet cover mounting panel or bar magnet mounting panel removed on the conveyer belt.
Furthermore, a connecting block in the conveying mechanism on one side is connected with the magnetic bar sleeve mounting plate, and a connecting block in the conveying mechanism on the other side is connected with the magnetic bar mounting plate.
Furthermore, a gland is arranged on the side wall of the connecting block, and a conveying connection groove is formed between the gland and the connecting block.
Further, the gland is connected with the connecting block through bolts.
Further, a magnetic rod sleeve main body is arranged at the bottom of the magnetic rod sleeve mounting plate, and a force application part extends from the side wall of the magnetic rod sleeve main body.
Furthermore, the force application part and the magnetic rod sleeve main body are made of the same material.
Further, a magnetic rod main body is arranged at the bottom of the magnetic rod mounting plate, and the magnetic rod sleeve main body is matched with the magnetic rod main body.
Furthermore, bearings are arranged at the joints of the rotating columns, the connecting blocks and the supports respectively.
The utility model has the advantages that: when the vibrating structure for the nucleic acid extractor of the utility model is used, which can improve the nucleic acid extraction efficiency,
1. the magnetic rod sleeve main body at the bottom of the magnetic rod sleeve mounting plate is driven by the conveying motor to move up and down to vibrate the extract to be extracted, the extract to be extracted is vibrated, the extract to be extracted is uniformly mixed, and after uniform mixing is finished, the magnetic rod main body is downwards moved and inserted into the magnetic rod sleeve main body, so that magnetic beads in the extract to be extracted are uniformly adsorbed at the bottom of the magnetic rod sleeve main body, the problem that the vibration of the extract to be extracted by the vibrating motor causes other structures to be loosened is avoided, the other structures are required to be screwed and fixed again, the stability of a vibration position is improved, the extraction efficiency of the extract to be extracted is improved, the vibration frequency cannot be controlled by using the vibration of the vibrating motor, the speed of the conveying motor for driving the magnetic rod sleeve main body to move up and down through the conveying belt can be controlled, the control of the vibration frequency is further realized, the extract to be extracted under the proper vibration frequency, and the extraction efficiency of the extract to be extracted is improved;
2. the magnetic rod sleeve main body is driven to move up and down through the conveying belt, so that the magnetic rod main body and the magnetic rod sleeve main body are conveniently driven to move and connect, meanwhile, the up-and-down moving speed of the magnetic rod sleeve main body is increased, the oscillation frequency of the extract to be extracted is increased, and the extraction efficiency of the extract to be extracted is further increased for the second time;
3. the magnetic rod sleeve main body is convenient to take and place by using the force application part.
Drawings
Other features, objects and advantages of the invention will become more apparent upon reading of the detailed description of non-limiting embodiments with reference to the following drawings:
FIG. 1 is a perspective view of an oscillating structure for a nucleic acid extractor of the present invention, which can improve the efficiency of nucleic acid extraction;
FIG. 2 is a side perspective view of an oscillating structure for a nucleic acid extractor of the present invention, which can improve the efficiency of nucleic acid extraction;
figure 3 is a front view of the present invention in figure 1;
FIG. 4 is a perspective view of the connection between the conveyer belt and the connecting block in the oscillating structure of the nucleic acid extracting apparatus of the present invention for improving the efficiency of nucleic acid extraction;
fig. 5 is an enlarged view of a in fig. 4 according to the present invention;
in the figure: the device comprises a support 1, a magnetic rod mounting plate 2, a magnetic rod main body 21, a magnetic rod sleeve mounting plate 3, a magnetic rod sleeve main body 31, a force application part 311, a sliding rail 4, a conveying mechanism 5, a driving wheel 51, a conveying motor 52, a conveying belt 53, a connecting block 54, a gland 541, a conveying joining groove 542, a rotating column 55, a joining block 56 and a driven wheel 57.
Detailed Description
In order to make the technical means, creation features, achievement purposes and functions of the present invention easy to understand, the present invention is further described below with reference to the following embodiments.
Referring to fig. 1-5, the present invention provides a technical solution: a vibrating structure for a nucleic acid extractor capable of improving nucleic acid extraction efficiency comprises a support 1, wherein a slide rail 4 is arranged on the support 1, a magnetic rod mounting plate 2 is arranged on one slide block of the slide rail 4, a magnetic rod sleeve mounting plate 3 arranged below the magnetic rod mounting plate 2 is arranged on the other slide block of the slide rail 4, and a conveying mechanism 5 for driving the magnetic rod sleeve mounting plate 3 and the magnetic rod mounting plate 2 to move up and down to vibrate an extract to be extracted is respectively arranged on two opposite side walls of the support 1;
Connecting block 54 in one side conveying mechanism 5 is connected with bar magnet cover mounting panel 3, connecting block 54 in the opposite side conveying mechanism 5 is connected with bar magnet mounting panel 2, this design is convenient for drive bar magnet mounting panel 2 and bar magnet cover mounting panel 3 reciprocate, thereby make bar magnet cover main part 31 of bar magnet cover mounting panel 3 bottom reciprocate and treat the extract and vibrate, avoid using vibrating motor to treat that the extract vibration leads to all the other structures not hard up, need tighten again fixedly to all the other structures, and then improve the stability of vibration department, improve the extraction efficiency of treating the extract, drive bar magnet cover main part 31 through conveyer belt 53 and reciprocate, be convenient for drive bar magnet main part 21 and bar magnet cover main part 31 and carry out the swing joint, improve the speed that bar magnet cover main part 31 reciprocated simultaneously, improve the oscillation frequency of extract, and then treat the secondary improvement and treat the extraction efficiency of extract.
The side wall of the connecting block 54 is provided with a gland 541, a conveying connection groove 542 is formed between the gland 541 and the connecting block 54, the conveying connection groove 542 is used for driving the connecting block 54 to move up and down conveniently, the gland 541 and the connecting block 54 are connected through bolts, the firmness of the connection position is improved through the bolts, the bottom of the magnetic rod sleeve mounting plate 3 is provided with a magnetic rod sleeve main body 31, the side wall of the magnetic rod sleeve main body 31 is extended with a force application part 311, and the magnetic rod sleeve main body 31 is convenient to take and place through the force application part 311.
As an embodiment of the present invention: when the extract to be extracted needs to vibrate, the conveying motors 52 on the two sides of the bracket 1 are firstly made to work to drive the magnetic bar mounting plate 2 and the magnetic bar sleeve mounting plate 3 to move to proper positions, the magnetic bar sleeve main body 31 at the bottom of the magnetic bar sleeve mounting plate 3 is made to contact with the extract to be extracted, the magnetic bar main body 21 at the bottom of the magnetic bar mounting plate 2 is made to move upwards to be separated from the interior of the magnetic bar sleeve main body 31, then the conveying motors 52 are made to drive the magnetic bar sleeve mounting plate 3 to move upwards and downwards, the magnetic bar sleeve mounting plate 3 moves upwards and downwards to drive the magnetic bar sleeve main body 31 at the bottom to move upwards and shake the extract to be extracted, the extract to be extracted needs to be screwed and fixed again after the extract to be uniformly mixed, then the magnetic bar main body 21 moves downwards to be inserted into the interior of the magnetic bar sleeve main body 31, magnetic beads in the interior of the extract to be extracted are uniformly adsorbed at the bottom of the magnetic bar sleeve main body 31 by using the magnetic bar main body 21, vibration of the extract to be extracted, the extract to be prevented from vibrating by using the vibration motors, the vibration of the extracting motors, the extracting motors can be controlled, the extracting efficiency of the extracting motor 52, and the extracting efficiency of the extract to be controlled, and the extracting efficiency of the extract to be suitable for extracting efficiency under the vibration of the extracting efficiency of the extract to be controlled.
Drive bar magnet cover main part 31 through conveyer belt 53 and reciprocate, be convenient for drive bar magnet main part 21 and bar magnet cover main part 31 and remove and be connected, improve the speed that bar magnet cover main part 31 reciprocated simultaneously, improve the oscillation frequency of treating the extract, and then the secondary improves the extraction efficiency of treating the extract, has improved the utility model discloses a practicality.
The basic principles and the main features of the invention and the advantages of the invention have been shown and described above, it will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, but that the invention may be embodied in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (8)
1. The utility model provides a can improve oscillating structure for nucleic acid extraction appearance of nucleic acid extraction efficiency which characterized in that: the device comprises a support (1), wherein a sliding rail (4) is arranged on the support (1), a magnetic rod mounting plate (2) is arranged on one sliding block of the sliding rail (4), a magnetic rod sleeve mounting plate (3) arranged below the magnetic rod mounting plate (2) is arranged on the other sliding block of the sliding rail (4), and conveying mechanisms (5) for driving the magnetic rod sleeve mounting plate (3) and the magnetic rod mounting plate (2) to move up and down to vibrate an extract to be extracted are respectively arranged on two opposite side walls of the support (1);
conveying mechanism (5) are including conveyor motor (52), conveyor motor (52) are installed inside support (1), be provided with action wheel (51) on the output shaft of conveyor motor (52), be provided with on support (1) lateral wall and lie in action wheel (51) linking piece (56) with one side, linking piece (56) internally mounted has rotation post (55), be provided with on rotation post (55) from driving wheel (57), action wheel (51) and be provided with conveyer belt (53) from between driving wheel (57), be provided with connecting block (54) that drive bar cover mounting panel (3) or bar magnet mounting panel (2) removed on conveyer belt (53).
2. The oscillating structure of claim 1 for nucleic acid extracting apparatus capable of improving nucleic acid extracting efficiency, wherein: the connecting block (54) in the conveying mechanism (5) on one side is connected with the magnetic bar sleeve mounting plate (3), and the connecting block (54) in the conveying mechanism (5) on the other side is connected with the magnetic bar mounting plate (2).
3. The oscillating structure of claim 1 for nucleic acid extracting apparatus capable of improving nucleic acid extracting efficiency, wherein: be provided with gland (541) on connecting block (54) lateral wall, form between gland (541) and connecting block (54) and carry and join in marriage groove (542).
4. The oscillating structure of claim 3 for nucleic acid extracting apparatus capable of improving nucleic acid extracting efficiency, wherein: the gland (541) is connected with the connecting block (54) through bolts.
5. The oscillating structure of claim 1 for nucleic acid extracting apparatus capable of improving nucleic acid extracting efficiency, wherein: the magnetic rod sleeve mounting plate is characterized in that a magnetic rod sleeve main body (31) is arranged at the bottom of the magnetic rod sleeve mounting plate (3), and a force application part (311) extends from the side wall of the magnetic rod sleeve main body (31).
6. The oscillating structure of claim 5 for nucleic acid extracting apparatus capable of improving nucleic acid extracting efficiency, wherein: the force application part (311) and the magnetic rod sleeve main body (31) are made of the same material.
7. The oscillating structure of claim 5 for nucleic acid extracting apparatus capable of improving nucleic acid extracting efficiency, wherein: the bottom of the magnetic bar mounting plate (2) is provided with a magnetic bar main body (21), and the magnetic bar sleeve main body (31) is matched with the magnetic bar main body (21).
8. The oscillating structure of claim 1 for nucleic acid extracting apparatus capable of improving nucleic acid extracting efficiency, wherein: and bearings are arranged at the joints of the rotating columns (55) and the connecting blocks (56) and the bracket (1) respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220273560.4U CN217855827U (en) | 2022-02-10 | 2022-02-10 | Can improve nucleic acid extraction efficiency's oscillating structure for nucleic acid extraction appearance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220273560.4U CN217855827U (en) | 2022-02-10 | 2022-02-10 | Can improve nucleic acid extraction efficiency's oscillating structure for nucleic acid extraction appearance |
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| Publication Number | Publication Date |
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| CN217855827U true CN217855827U (en) | 2022-11-22 |
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| CN202220273560.4U Active CN217855827U (en) | 2022-02-10 | 2022-02-10 | Can improve nucleic acid extraction efficiency's oscillating structure for nucleic acid extraction appearance |
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| CN (1) | CN217855827U (en) |
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