CN217848623U - Drive circuit, laser module and cell particle analyzer - Google Patents

Abstract

The utility model discloses a drive circuit of laser instrument, laser module and cell particle analyzer, drive circuit includes power module, power detection module, power setting module and integral module, power module's output is connected with the laser instrument, and power supply signal intensity is adjustable, power detection module is used for generating first signal of telecommunication according to the output power of laser instrument, power setting module is used for setting up the signal according to power and generating the second signal of telecommunication, integral module and power module, power detection module and power setting module are connected, be used for carrying out the difference integral to the second signal of telecommunication and first signal of telecommunication in order to export the regulation signal who generates to power module, power module still is used for adjusting power supply signal's signal intensity according to regulation signal, make the output and the target power matching of laser instrument, thereby make drive circuit stably drive the laser instrument, reduce the influence to laser instrument output when receiving the interference, with the stability of promotion laser instrument output in the course of work.

Description

Driving circuit, laser module and cell particle analyzer

Technical Field

The application relates to the field of medical equipment, in particular to a driving circuit, a laser module and a cell particle analyzer.

Background

At present, people often sample a sample of human blood, urine, etc. to make a corresponding sample to be tested, irradiate the sample to be tested with light through a cell particle analyzer, collect optical signals generated by the light irradiation of each particle in the sample to be tested, and analyze an optical signal element to obtain an analysis result of the corresponding sample to be tested.

However, when the cell particle analyzer irradiates the sample to be measured with light, the driving circuit drives the laser device to emit laser light and irradiate the sample to be measured, and the stability of the output power of the laser device during the working process is poor, for example, the output power of the laser device fluctuates due to the interference of the driving circuit, which affects the acquisition result of the optical signal and ultimately affects the analysis result of the sample to be measured.

SUMMERY OF THE UTILITY MODEL

The embodiment of the utility model provides a main objective is providing a drive circuit, laser module and cell particle analyzer, aims at controlling drive circuit stable drive laser instrument, reduces the influence to laser instrument output when drive circuit receives the interference to promote laser instrument output's stability in the course of the work.

In a first aspect, an embodiment of the present invention provides a driving circuit, including:

a driving circuit of a laser for irradiating a cell particle, comprising:

the output end of the power supply module is connected with the laser and used for supplying power to the laser, and the power supply signal intensity of the power supply module is adjustable;

the power detection module is used for detecting the output power of the laser and generating a first electric signal according to the output power;

the power setting module is used for receiving an input power setting signal and generating a second electric signal according to the power setting signal;

the input end of the integration module is connected with the output end of the power detection module and the output end of the power setting module respectively, the output end of the integration module is connected with the power supply module, and the integration module is used for receiving the first electric signal and the second electric signal, performing differential integration on the second electric signal and the first electric signal to generate an adjusting signal, and outputting the adjusting signal to the power supply module;

the power supply module is further used for adjusting the signal intensity of the power supply signal according to the adjusting signal so that the output power of the laser is matched with the target power corresponding to the power setting signal.

In some embodiments, the integration module comprises at least an operational amplifier, an integration resistor and an integration capacitor;

the power supply device comprises an operational amplifier, a power setting module, an integrating resistor, a power detection module, a power supply module, an integrating capacitor and a power supply module, wherein the non-inverting input end of the operational amplifier is connected with the power setting module, the inverting input end of the operational amplifier is connected with the power detection module through the integrating resistor, the output end of the operational amplifier is connected with the power supply module, one end of the integrating capacitor is connected with the inverting input end of the operational amplifier, and the other end of the integrating capacitor is connected with the output end of the operational amplifier.

In some embodiments, the value of the product of the resistance of the integrating resistor and the capacitance of the integrating capacitor is adapted to the pulse width of the pulse signal generated by the laser irradiating the cell particles.

In some embodiments, the product of the resistance value of the integrating resistor and the capacitance value of the integrating capacitor ranges from 0.001 second to 0.2 second.

In some embodiments, the power module comprises:

the power supply interface is used for connecting a power supply;

the power supply switch tube, the controlled end and the integral module of power supply switch tube are connected, the first end and the laser instrument of power supply switch tube are connected, the second end and the power supply interface connection of power supply switch tube, power supply passes through power supply interface and exports power signal to the power supply switch tube, power supply switch tube is used for obtaining power supply signal according to the signal intensity of the regulation signal regulation power signal of self-controlled end input to with power supply signal output to the laser instrument.

In some embodiments, the power supply module further includes a protection circuit, and the power supply interface is connected to the second end of the power supply switch tube through the protection circuit.

In some embodiments, the protection circuit comprises at least two protection resistors, wherein the at least two protection resistors are connected in series between the power supply interface and the second end of the power supply switching tube.

In some embodiments, the power setting module includes a potentiometer, a potential output terminal of the potentiometer is connected to the integrating module, and the potentiometer is configured to receive an externally input power setting signal, generate a corresponding potential signal according to the power setting signal, and output the potential signal as the second electrical signal from the potential output terminal.

In a second aspect, the embodiment of the present invention further provides a laser module, including a laser and a driving circuit provided in any embodiment of the present specification, wherein the driving circuit is connected to the laser for driving the laser to perform light irradiation.

In a third aspect, the present invention provides a cell particle analyzer, including:

the sample supply device is used for providing a sample to be tested;

a reagent supply device for supplying a reaction reagent;

the reaction device is used for providing a reaction site for the sample to be detected and the reaction reagent so as to mix the sample to be detected and the reagent to form a sample to be detected;

the optical detection device is used for carrying out light irradiation on a sample to be detected, collecting optical signals generated by each particle in the sample to be detected due to the light irradiation, and acquiring corresponding detection data according to the optical signals;

the conveying device is used for conveying the sample to be detected in the reaction device to the optical detection device;

wherein, optical detection device is including gathering the module and the laser module that any embodiment of this application specification provided, gathers the module and is arranged in gathering each particle in the sample that awaits measuring and because of the produced optical signal of light struck.

To sum up, the utility model provides a drive circuit of laser instrument, laser module and cell particle analyzer, the laser instrument is used for shining the cell particle, drive circuit includes power module, power detection module, power setting module and integral module, wherein, power module's output is connected with the laser instrument, be used for to the laser instrument power supply, and power module's power supply signal intensity is adjustable, power detection module is used for detecting the output of laser instrument and generates first signal of telecommunication according to output power, power setting module is used for receiving the power setting signal of input, and according to power setting signal generation second signal of telecommunication, integral module's input and power detection module's output and power setting module's output are connected respectively, integral module's output and power module are connected, and integral module is used for receiving first signal of telecommunication and second signal of telecommunication, carry out the difference integral with the generation regulating signal to the second signal of telecommunication and first signal of telecommunication, and with regulating signal output to power module, power module still is used for according to regulating signal regulating power supply signal's signal intensity, so that the output of output power that the laser instrument and power setting signal correspond matches, thereby make the drive circuit stable drive circuit, the output of laser instrument influences the laser in the laser instrument output process of promotion.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without any creative effort.

Fig. 1 is a schematic diagram of a module structure of a driving circuit provided by the present invention;

fig. 2 is a schematic circuit structure diagram of an integrating module of the driving circuit according to the present invention;

fig. 3 is a schematic circuit diagram of a driving circuit according to an embodiment of the present invention;

fig. 4 is a schematic circuit diagram of a driving circuit according to another embodiment of the present invention;

fig. 5 is a schematic diagram of a module structure of a laser module according to the present invention;

fig. 6 is a schematic diagram of a module result of the cell particle analyzer according to the present invention.

Reference numerals are as follows:

1. a cell particle analyzer; 10. a laser module; 20. a collection module; 30. a processor; 40. an optical detection device; 50. a sample supply device; 60. a reagent supply device; 70. a reaction device; 80. a conveying device; 100. a drive circuit; 110. a power supply module; 111. a power supply interface; 112. a protection circuit; 120. a power detection module; 130. a power setting module; 131. a reference signal interface; 132. a mechanical potentiometer; 133. a center tap; 134. a potential control terminal; 140. an integration module; 200. a laser; r1, an integral resistor; r2, a first protection resistor; r3, a second protection resistor; r4, a conversion resistor; c1, an integrating capacitor; u1, an operational amplifier; u2, an electronic potentiometer; q1, a power supply switch tube; d1, a semiconductor laser; d2, a photodiode.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "left", "right", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

At present, people often sample a sample of human blood, urine, etc. to make a corresponding sample to be tested, irradiate the sample to be tested with light through a cell particle analyzer, collect optical signals generated by the light irradiation of each particle in the sample to be tested, and analyze an optical signal element to obtain an analysis result of the corresponding sample to be tested. However, when the cell particle analyzer irradiates the sample to be measured with light, the driving circuit drives the laser device so that the laser device emits laser light and irradiates the sample to be measured, and the stability of the output power of the laser device during the working process is poor, for example, the output power of the laser device fluctuates due to the interference of the driving circuit, which affects the acquisition result of the optical signal and ultimately affects the analysis result of the sample to be measured.

Based on this, this application provides a drive circuit, signal analysis module and cell particle analysis appearance, aims at controlling the drive circuit and stably drives the laser instrument, reduces the influence to laser instrument output power when drive circuit receives the interference to promote laser instrument output power's stability in the course of the work. In the following, some embodiments of the present invention are described in detail with reference to the accompanying drawings, and features in the following examples and examples may be combined with each other without conflict.

Referring to fig. 1, fig. 1 is a schematic diagram of a module structure of a driving circuit according to the present invention.

As shown in fig. 1, the laser 200 is used for irradiating cell particles, and the driving circuit 100 of the laser 200 includes a power supply module 110, a power detection module 120, a power setting module 130, and an integration module 140.

Specifically, the output end of the power supply module 110 is connected to the laser 200, and is configured to supply power to the laser 200, the strength of the power supply signal of the power supply module 110 is adjustable, and the output power of the laser 200 can be controlled by adjusting the strength of the power supply signal, the power detection module 120 is configured to detect the output power of the laser 200, and generate a first electrical signal according to the output power, the power setting module 130 is configured to receive an input power setting signal, generate a second electrical signal according to the power setting signal, and output the second electrical signal to the integration module 140, the input end of the integration module 140 is connected to the output end of the power detection module 120 and the output end of the power setting module 130, the output end of the integration module 140 is connected to the power supply module 110, and the integration module 140 is configured to receive the first electrical signal and the second electrical signal, differentially integrate a signal strength difference between the second electrical signal and the first electrical signal to generate an adjustment signal, and output the adjustment signal to the power supply module 110, where the power supply module 110 is further configured to adjust the signal strength of the power output of the laser 200 to match a target power corresponding to the power setting signal.

It should be understood that the power setting signal may be input to the power setting module 130 from outside the driving circuit 100, for example, a power setting signal manually operated by a user to input the power setting signal to the power setting module 130, wherein the power setting signal corresponds to a target power, and the target power may be a power at which the user instructs the driving circuit 100 to drive the laser 200 to output laser light, and it is easy to know that the output power of the laser 200 is stabilized around the target power when the output power of the laser 200 matches the target power corresponding to the power setting signal.

The integration module 140 is arranged to perform differential integration on the second electrical signal and the first electrical signal to generate an adjustment signal, and the adjustment signal is used to adjust the intensity of the power supply signal output by the power supply module 110 to the laser 200, so that the driving circuit 100 can stably drive the laser 200, and the influence of interference on the output power of the laser 200 by the driving circuit 100 is reduced. Specifically, when the output power of the laser 200 fluctuates slightly, the signal intensity of the second electrical signal fluctuates accordingly, the integrating module 140 performs differential integration on the second electrical signal and the first electrical signal, and can quickly respond to the fluctuation of the output power of the laser 200 to generate a corresponding adjusting signal, so as to adjust the power supply signal output by the power supply module 110 in real time, so that the output power of the laser 200 is stabilized at the target power, and therefore, the stability of the output power of the laser 200 in the working process and the real-time performance of the driving circuit 100 in adjusting the output power of the laser 200 are significantly improved.

Exemplarily, the utility model provides a drive circuit 100 of laser instrument 200 can be used for driving laser instrument 200 and carry out stable light irradiation to waiting to detect the reagent sample, for example carry out stable light irradiation to the sample that awaits measuring that flows through the optics flow room, then gather the optical signal that each particle response light irradiation generated in the sample that awaits measuring and further carry out the analysis to optical signal, can promote the reliability of medical analysis result.

Please refer to fig. 2, fig. 2 is a schematic circuit structure diagram of an integrating module of a driving circuit according to the present invention.

As shown in fig. 2, in some embodiments, the integrating module 140 at least includes an operational amplifier U1, an integrating resistor R1 and an integrating capacitor C1, wherein a non-inverting input terminal of the operational amplifier U1 is connected to the power setting module 130, an inverting input terminal of the operational amplifier U1 is connected to the power detecting module 120 through the integrating resistor R1, an output terminal of the operational amplifier U1 is connected to the power supply module 110, one end of the integrating capacitor C1 is connected to the inverting input terminal of the operational amplifier U1, and the other end is connected to the output terminal of the operational amplifier U1.

Specifically, the operational amplifier U1, the integrating resistor R1 and the integrating capacitor C1 are used in cooperation to perform differential integration on the signal intensity difference between the second electrical signal and the first electrical signal, and output the signal obtained by the integration as an adjustment signal to the power supply module 110. It should be understood that the operational amplifier U1, the integrating resistor R1 and the integrating capacitor C1 constitute an integrator.

In some embodiments, the product of the resistance of the integrating resistor R1 and the capacitance of the integrating capacitor C1 is adapted to the pulse width of the cell particles irradiated by the laser 200.

It should be understood that the product of the resistance value of the integrating resistor R1 and the capacitance value of the integrating capacitor C1 is a time constant corresponding to the integrator in the integrating module 140, where the time constant is a time required for the voltage difference value at two ends of the integrating capacitor C1 to reach a steady state, that is, when the values of the second electrical signal and the first electrical signal change, the integrating module 140 needs a time from a time point when the adjustment signal starts to change by performing differential integration on the second electrical signal and the first electrical signal to a time point when the steady-state adjustment signal is output.

It should be noted that the time constant corresponding to the integrator in the integration module 140 is adapted to the pulse width of the pulse signal generated by the laser 200 irradiating the cell particles. Specifically, the product of the resistance value of the integrating resistor R1 and the capacitance value of the integrating capacitor C1, i.e., the time constant corresponding to the integrator, needs to be greater than the pulse width of the pulse signal, so that the integrating module 140 can smoothly adjust the intensity of the power supply signal output by the power supply module 110 to the laser 200.

In some embodiments, the product of the resistance value of the integrating resistor R1 and the capacitance value of the integrating capacitor C1 ranges from 0.001 second to 0.2 second.

It should be understood that, in the field of cell detection, when the laser 200 is driven by the driving circuit 100 in the cell particle analyzer 1 to convect the sample to be tested flowing through the optical flow cell, the time interval between two adjacent cell particles in the sample to be tested flowing to the same position in the optical flow cell is generally 1.5 μ second to 4 μ second, that is, the pulse width of the pulse signal is 1.5 μ second to 4 μ second, and the product of the resistance value of the integrating resistor R1 and the capacitance value of the integrating capacitor C1 needs to be greater than the pulse width of the pulse signal, so that the product of the resistance value of the integrating resistor R1 and the capacitance value of the integrating capacitor C1 ranges from 0.001 second to 0.2 second, so that the integrating module 140 smoothly adjusts the intensity of the power supply signal output by the power supply module 110.

Referring to fig. 3, fig. 3 is a schematic circuit structure diagram of a driving circuit according to the present invention.

As shown in fig. 3, in some embodiments, the power supply module 110 includes a power supply interface 111 and a power supply switch Q1.

Specifically, the power supply interface 111 is configured to connect a power supply, the controlled end of the power supply switch tube Q1 is connected to the integrating module 140, the first end of the power supply switch tube Q1 is connected to the laser 200, the second end of the power supply switch tube Q1 is connected to the power supply interface 111, the power supply outputs a power supply signal to the power supply switch tube Q1 through the power supply interface 111, and the power supply switch tube Q1 is configured to adjust the signal strength of the power supply signal according to an adjustment signal input from the controlled end to obtain a power supply signal and output the power supply signal to the laser 200. It should be noted that the output power of the laser 200 is positively correlated with the signal strength of the power supply signal.

For example, the power supply may be a preset negative power supply, and is configured to output a power supply signal with a negative voltage value to the power supply switch Q1 through the power supply interface 111.

For example, the power supply switching tube Q1 may be a triode, and a workflow of the integration module 140 adjusting the output power of the laser 200 according to the signal intensity difference integration result of the second electrical signal and the first electrical signal is described below by taking the power supply switching tube Q1 as an NPN type triode and taking the power supply as a preset negative power supply as an example.

The base of the power supply switch tube Q1 is connected with the output end of the integrating module 140, and is used for receiving the adjusting signal, the emitter of the power supply switch tube Q1 is connected with the power supply interface 111, and the laser 200 is connected between the collector of the power supply switch tube Q1 and the ground, so that the laser 200, the power supply switch tube Q1 and the power supply interface 111 cooperate to form a power supply loop, the flowing direction of the current on the power supply loop sequentially flows through the laser 200, the power supply switch tube Q1 and the power supply interface 111 from the ground to reach a preset negative power supply, and the current intensity on the power supply loop is the signal intensity of the power supply signal.

When the first electrical signal is greater than the second electrical signal, the output power of the characterization laser 200 is greater than the target power corresponding to the power setting signal, and at this time, the integration module 140 integrates the signal intensity difference between the second electrical signal and the first electrical signal to obtain a signal intensity drop of the adjustment signal, so that the current intensity between the emitter and the collector of the power supply switching tube Q1 drops, and the output power of the laser 200 drops accordingly until the output power is stabilized at the target power corresponding to the power setting signal.

When the first electrical signal is smaller than the second electrical signal, the output power of the characterization laser 200 is smaller than the target power corresponding to the power setting signal, and at this time, the integration module 140 integrates the signal intensity difference between the second electrical signal and the first electrical signal to obtain an increase in signal intensity of the adjustment signal, so that the current intensity between the emitter and the collector of the power supply switching tube Q1 increases, and the output power of the laser 200 increases accordingly until the output power is stabilized at the target power corresponding to the power setting signal.

In some embodiments, the power supply module 110 further includes a protection circuit 112, and the power supply interface 111 is connected to the second end of the power supply switch Q1 through the protection circuit 112. It should be understood that the power supply interface 111, the protection circuit 112, the power supply switch Q1 and the laser 200 cooperate to form a power supply loop, and the power supply interface 111 is used for supplying power to the laser 200 through the power supply loop. The protection circuit 112 may be configured to absorb a part of the current flowing through the power supply loop to further adjust the current flowing into the laser 200, so as to protect the laser 200 and the power supply switch Q1.

In some embodiments, the protection circuit 112 includes at least two protection resistors, wherein the at least two protection resistors are connected in series between the power interface 111 and the second end of the power switch Q1. For example, as shown in fig. 3, the protection circuit 112 at least includes a first protection resistor R2 and a second protection resistor R3, and the first protection resistor R2 and the second protection resistor R3 are connected in series between the power supply interface 111 and the second end of the power supply switch Q1.

Specifically, at least one of the protection resistors is replaceable or adjustable in resistance value, and the current on the power supply loop can be further adjusted by replacing the protection resistor or adjusting the resistance value of the protection resistor, so that the laser 200 and the power supply switch tube Q1 are protected.

In some embodiments, the power setting module 130 includes a potentiometer, a potential output terminal of which is connected to the integrating module 140, and the potentiometer is configured to receive an externally input power setting signal, generate a corresponding potential signal according to the power setting signal, and output the potential signal as the second electrical signal from the potential output terminal.

Specifically, the potentiometer in the power setting module 130 includes, but is not limited to, one of a mechanical potentiometer 132 and an electronic potentiometer U2, and one of the mechanical potentiometer 132 and the electronic potentiometer U2 is configured to receive an externally input power setting signal, generate a corresponding potential signal according to the power setting signal, and output the potential signal as a second electrical signal from a potential output end to the integrating module 140.

As shown in fig. 3, taking the mechanical potentiometer 132 as an example, a first end and a second end of the mechanical potentiometer 132 are respectively connected to the reference signal interface 131 and the ground, and the mechanical potentiometer 132 is configured to convert a reference signal input by the reference signal interface 131 into a corresponding mechanical potential signal according to an external moving operation on a center tap 133 of the mechanical potentiometer 132, and output the mechanical potential signal as a second electrical signal from the potential output end to the integrating module 140.

As shown in fig. 4, an electronic potentiometer U2 may also be used as the potentiometer connected to the integrating module 140, and particularly, in the case that it is not suitable for directly operating the potentiometer, the electronic potentiometer U2 is used as the potentiometer connected to the integrating module 140, and a power setting signal is input to the potential control terminal 134 of the electronic potentiometer U2, so that the electronic potentiometer U2 generates a corresponding electronic potential signal according to the power setting signal, and outputs the electronic potential signal as a second electric signal from the potential output terminal to the integrating module 140.

As shown in fig. 3 and 4, in some embodiments, the power detection module 120 at least includes a photoelectric sensing device and a conversion resistor R4, the photoelectric sensing device is disposed corresponding to the laser 200 and is configured to sense illumination output by the laser 200 to generate an induced current, and the conversion resistor R4 is connected between the photoelectric sensing device and ground and is configured to convert the induced current into a voltage signal and output the voltage signal as the first electrical signal to the integration module 140.

Illustratively, the Photo sensing device may employ a photodiode (PD, photo-Diode), specifically, an anode of the photodiode is connected to the integrating module 140, a cathode of the photodiode is grounded, and the converting resistor R4 is connected between the anode of the photodiode and the ground. The photodiode senses the illumination output by the laser 200 to generate an induced current, and the conversion resistor R4 converts the induced current into a voltage signal and outputs the voltage signal as a first electrical signal to the integration module 140.

The embodiment of the utility model provides a still provide a laser module, please refer to and draw in 5, fig. 5 is the utility model provides a module structure schematic diagram of laser module.

As shown in fig. 5, the laser module 10 includes a laser 200 and a driving circuit 100 provided in any embodiment of the present disclosure, wherein the driving circuit 100 is connected to the laser 200 and is configured to drive the laser 200 to perform light irradiation.

It should be understood that the output power of the laser 200 output laser light is related to the strength of the power supply signal output by the driving circuit 100. Illustratively, the Laser 200 may employ a semiconductor Laser D1 (LD). Specifically, the anode of the semiconductor laser D1 is grounded, and the cathode is connected to a predetermined negative power supply through the power supply switching tube Q1 and the power supply interface 111, so that the current flowing from the anode to the cathode of the semiconductor laser D1 is used as a power supply signal to excite the semiconductor laser D1 to output laser light for light irradiation.

In some embodiments, the laser 200 and the photo sensing device in the power detection module 120 of the driving circuit 100 may be packaged in a set, for example, the semiconductor laser D1 and the photodiode may be packaged in a set, so that the photodiode can directly sense the laser output by the semiconductor laser D1 to generate a corresponding sensing current, so as to improve the accuracy of the power detection module 120 of the driving circuit 100 for detecting illumination, further improve the integration level of the laser module 10, and reduce the space occupied by the laser module 10.

The embodiment of the utility model provides a still provide a cell particle analyzer, please refer to and draw in fig. 6, fig. 6 is the utility model provides a cell particle analyzer's modular structure schematic diagram.

As shown in FIG. 6, the cell particle analyzer 1 includes a sample supply unit 50, a reagent supply unit 60, a reaction unit 70, an optical detection unit 40, and a transport unit 80. Specifically, the sample supply device 50 is configured to provide a sample to be tested, the reagent supply device 60 is configured to provide a reaction reagent, the reaction device 70 is configured to provide a reaction site for the sample to be tested and the reaction reagent, so that the sample to be tested and the reagent are mixed to form a sample to be tested, the optical detection device 40 is configured to perform light irradiation on the sample to be tested, collect optical signals generated by light irradiation of particles in the sample to be tested, so as to obtain corresponding detection data according to the optical signals, and the conveying device 80 is configured to convey the sample to be tested in the reaction device 70 to the optical detection device 40. The optical detection device 40 includes an acquisition module 20 and the laser module 10 provided in any embodiment of the present application, and the acquisition module 20 is configured to acquire an optical signal generated by each particle in the sample to be detected due to light irradiation.

Further, the optical detection device 40 of the cell particle analyzer 1 further includes a processor 30, and the processor 30 is connected to the collection module 20 and is configured to further analyze the optical signal collected by the collection module 20 to obtain the health information corresponding to the sample to be tested.

Illustratively, the Processor 30 includes, but is not limited to, a Programmable Logic Controller (PLC), a Central Processing Unit (CPU), a Micro Control Unit (MCU), other general purpose Processor 30, a Digital Signal Processor (DSP), an Application Specific Integrated Circuit (ASIC), an off-the-shelf Programmable Gate Array (FPGA) or other Programmable Logic device, discrete Gate or transistor Logic, discrete hardware components, and the like.

To sum up, the utility model provides a drive circuit 100 of laser instrument 200, laser module 10 and cell particle analyzer 1, laser instrument 200 is used for shining the cell particle, drive circuit 100 includes power module 110, power detection module 120, power setting module 130 and integral module 140, wherein, power module 110's output is connected with laser instrument 200, be used for to laser instrument 200 power supply, and power module 110's power supply signal intensity is adjustable, power detection module 120 is used for detecting laser instrument 200's output power and generates first electric signal according to output power, power setting module 130 is used for receiving the power setting signal of input, and according to power setting signal generation second electric signal, integral module 140's input and power detection module 120's output and power setting module 130's output are connected respectively, integral module 140's output is connected with power module 110, and integral module 140 is used for receiving first electric signal and second electric signal, carry out differential integration to second electric signal and first electric signal in order to generate the regulation signal, and export regulation signal to power module 110, power module 110 is still used for adjusting the power supply signal according to the regulation signal, thereby the stability of the output of laser instrument 200 makes the laser output stable when the drive circuit 200, thereby the output of laser instrument 200 makes the laser instrument output stable output.

The above disclosure provides many different embodiments or examples for implementing different features of the invention. In order to simplify the disclosure of the present invention, the components and arrangements of the specific examples are described above. Of course, they are merely examples and are not intended to limit the present invention. Furthermore, the present invention may repeat reference numerals and/or reference letters in the various examples, which have been repeated for purposes of simplicity and clarity and do not in themselves dictate a relationship between the various embodiments and/or arrangements discussed. In addition, the present disclosure provides examples of various specific processes and materials, but one of ordinary skill in the art may recognize the application of other processes and/or the use of other materials.

While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims (10)

1. A drive circuit for a laser for irradiating a cell particle, comprising:

the output end of the power supply module is connected with the laser and used for supplying power to the laser, and the power supply signal intensity of the power supply module is adjustable;

the power detection module is used for detecting the output power of the laser and generating a first electric signal according to the output power;

the power setting module is used for receiving an input power setting signal and generating a second electric signal according to the power setting signal;

the input end of the integration module is connected with the output end of the power detection module and the output end of the power setting module respectively, the output end of the integration module is connected with the power supply module, and the integration module is used for receiving the first electric signal and the second electric signal, performing differential integration on the second electric signal and the first electric signal to generate an adjusting signal, and outputting the adjusting signal to the power supply module;

the power supply module is further configured to adjust the signal strength of the power supply signal according to the adjustment signal, so that the output power of the laser matches a target power corresponding to the power setting signal.

2. The driving circuit of claim 1, wherein the integration module comprises at least an operational amplifier, an integration resistor and an integration capacitor;

the power supply module is connected with the operational amplifier, the power setting module is connected with the operational amplifier, the power detection module is connected with the operational amplifier, the power supply module is connected with the operational amplifier, the non-inverting input end of the operational amplifier is connected with the power setting module, the inverting input end of the operational amplifier is connected with the power supply module, one end of the integrating capacitor is connected with the inverting input end of the operational amplifier, and the other end of the integrating capacitor is connected with the output end of the operational amplifier.

3. The driving circuit according to claim 2, wherein a value of a product of a resistance of the integrating resistor and a capacitance of the integrating capacitor is adapted to a pulse width of a pulse signal generated by the laser irradiating the cell particles.

4. The driving circuit of claim 3, wherein the product of the resistance of the integrating resistor and the capacitance of the integrating capacitor ranges from 0.001 second to 0.2 second.

5. The driving circuit according to any one of claims 1 to 4, wherein the power supply module comprises:

the power supply interface is used for connecting a power supply;

the power supply switch tube, the controlled end of power supply switch tube with the integral module is connected, the first end of power supply switch tube with the laser instrument is connected, the second end of power supply switch tube with power interface connection, power supply passes through power interface to power supply switch tube output power signal, power supply switch tube is used for adjusting according to the regulation signal of controlling the end input power signal's signal strength obtains power signal, and will power signal output extremely the laser instrument.

6. The driving circuit according to claim 5, wherein the power supply module further comprises a protection circuit, and the power supply interface is connected to the second end of the power supply switch tube through the protection circuit.

7. The driving circuit according to claim 6, wherein the protection circuit comprises at least two protection resistors, wherein at least two protection resistors are connected in series between the power supply interface and the second end of the power supply switching tube.

8. The driving circuit according to any one of claims 1 to 4, wherein the power setting module comprises a potentiometer, a potential output terminal of the potentiometer is connected to the integrating module, and the potentiometer is configured to receive an externally input power setting signal, generate a corresponding potential signal according to the power setting signal, and output the potential signal as the second electrical signal from the potential output terminal.

9. A laser module comprising a laser and a driving circuit according to any one of claims 1 to 8, wherein the driving circuit is connected to the laser for driving the laser to irradiate light.

10. A cell particle analyzer, comprising:

the sample supply device is used for providing a sample to be tested;

a reagent supply device for supplying a reaction reagent;

the reaction device is used for providing a reaction site for the sample to be detected and the reaction reagent so as to mix the sample to be detected and the reagent to form a sample to be detected;

the optical detection device is used for irradiating a sample to be detected with light, collecting optical signals generated by the irradiation of the light on each particle in the sample to be detected, and acquiring corresponding detection data according to the optical signals;

the conveying device is used for conveying the sample to be detected in the reaction device to the optical detection device;

the optical detection device comprises a collection module and the laser module set according to claim 9, wherein the collection module is used for collecting optical signals generated by the light irradiation of the particles in the sample to be detected.

Images