CN217793233U - Multifunctional thrombus treatment device - Google Patents

Multifunctional thrombus treatment device Download PDF

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Publication number
CN217793233U
CN217793233U CN202220040764.3U CN202220040764U CN217793233U CN 217793233 U CN217793233 U CN 217793233U CN 202220040764 U CN202220040764 U CN 202220040764U CN 217793233 U CN217793233 U CN 217793233U
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thrombus
diameter
guide wire
support
catheter
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吴天根
毕玉影
冯骏华
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Dongguan Tiantianxiangshang Medical Technology Co ltd
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Dongguan Tiantianxiangshang Medical Technology Co ltd
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Abstract

The utility model provides a multi-functional thrombus treatment device, multi-functional thrombus treatment device is including the guide wire, but the variable diameter is got and is tied the support, fixed catheter and recovery pipe, wherein, but the variable diameter is got the distal end net portion density of tying the support great, in order to realize netting the tiny thrombus of escape, but the variable diameter is got the distal end of tying the support and is equipped with the slip opening and overlaps outside the guide wire, the near-end is connected with fixed catheter's distal end, but through adjusting the straight warp of the adjustable diameter of guide wire and fixed catheter's position regulation embolus support, fully catch the thrombus of different sizes in the blood vessel, the recovery pipe cover is located fixed catheter's outer wall and can be used for accommodating but the variable diameter is got and ties the support, not only the diameter that can change the variable diameter is got and tie the thrombus with the capture of maximum repeatedly, outside the net is lived, to great, the thrombus that is difficult to catch can also dissolve in advance through fixed and recovery pipe, it catches after the miniaturization again, realize dissolving, it accomplishes simultaneously to get the thrombus and the multiple treatment method of net bolt.

Description

Multifunctional thrombus treatment device
Technical Field
The utility model relates to the field of medical equipment, especially, relate to a multi-functional thrombus treatment device that helps realizing thrombolysis and thrombectomy simultaneously.
Background
Abnormal blood flow in blood vessels is caused by abnormal blood flow in the blood vessels, and the abnormal blood flow can cause a series of adverse effects such as tissue hypoxia, abnormal intravascular pressure, cardiac load aggravation and even heart failure, so the abnormal blood flow in the blood vessels generally needs to be restored or rebuilt through a catheter intervention technology.
Many adverse consequences also arise when a blood vessel is constricted or occluded, such as turbulent blood flow, slow flow rates, and the formation of blood clots that restrict blood supply to areas downstream of the vascular system. Stroke may be initiated when a blood clot is located in the neurovascular system; when a blood clot is located in the pulmonary artery vasculature, pulmonary embolism may be initiated, leading to patient death. In addition, obstructions such as atherosclerosis and plaques thereof may also become dangerous when they restrict blood flow, causing abnormal blood flow, causing various vascular diseases.
Therefore, there is a clinical need for an effective drug, device or/and system for removing thrombus plaque, so as to remove the plaque blockage in the blood vessel in time, open the occluded blood vessel, capture the sloughed thrombus tissue, and reduce ischemia and necrosis of the distal organ tissue blood vessel caused by the sloughed thrombus.
At present, thrombolysis, mechanical thrombus removal and other methods are widely adopted to remove thrombus. Thrombolytic therapy is mainly to remove thrombus plaques by injecting thrombolytic drugs into thrombus positions through catheters, the method is mostly used for early thromboembolism and has poor effects on large plaques and long-term hardened plaques, and percutaneous mechanical thrombus removal (PMT) is to remove intravascular obstructions by using a mechanical device, and comprises the modes of dissolution, crushing, suction, stent or basket thrombus removal and the like, and is a current clinical main treatment means.
One type of conventional percutaneous mechanical thrombectomy device is to insert a balloon catheter into the blood vessel and through the clot, and then expand the balloon to compress the clot against the vessel wall or into the distal vessel to open the blocked vessel. This method cannot remove the thrombus, and the biggest problem is that the crushed thrombus falls off, resulting in re-embolization of the distal blood vessel.
Another type of self-expanding stent is delivered to the thrombus site through a microcatheter, from which the stent, when released for expansion, embeds the thrombus within the stent and then withdraws into the catheter. In this method, although the thrombus can be removed compared with the above-mentioned balloon dilatation, since the diameter of the stent after the expansion is fixed and disposable, if the thrombus cannot be captured for the first time, the thrombus removal operation fails, and on the other hand, since the mesh of the stent is fixed, only the thrombus smaller than the mesh of the stent can be captured and the thrombus larger than the mesh is substantially ineffective, so that the clinical effect thereof is limited. In addition, since the distal end of the stent is developed for this method, there is also a problem of thrombus escape.
Therefore, the single traditional thrombus treatment method, whether thrombolysis, balloon thrombus expansion or mechanical thrombus removal, can not effectively treat the thrombus problem. The inventors have considered that, in order to solve the above problems, a clinically ideal mechanical thrombectomy device should include both: 1) can provide the passageway that the thrombolytic drug pours into, 2) powerful thrombus capture ability, and 3) prevent the function that the thrombus plaque escaped that drops, the utility model is such a section collect catheter drug thrombolysis, high-efficient machinery get the bolt and prevent thrombus escape in the innovation product of an organic whole, and the machinery among the prior art is got and is tied the device and lack above-mentioned function.
SUMMERY OF THE UTILITY MODEL
The utility model provides a multi-functional thrombus treatment device has set up the passageway that can provide the thrombolytic drug and pour into, and has the function that powerful thrombus seizure ability and prevent the escape of the thrombus plaque that drops, helps effectively solving single thrombus treatment device in, has the thrombus to drop, gets to tie the poor scheduling problem of effect.
The utility model provides a multi-functional thrombus treatment device, include:
a guide wire;
the recovery catheter is sleeved on the outer wall of the guide wire, and a first containing cavity is formed between the inner wall of the recovery catheter and the outer wall of the guide wire;
but reducing thrombectomy support, but reducing thrombectomy support is network structure, the guide wire is worn to locate but reducing thrombectomy support, but the diameter of reducing thrombectomy support is changeable, but reducing thrombectomy support is through changing the blood vessel or the thrombus of self diameter in order to be suitable for different width, first appearance chamber is used for accomodating but reducing thrombectomy support is used for carrying the medicine.
According to the utility model discloses an embodiment, but variable diameter thrombectomy support is including the distal end portion of netting, middle portion of netting and the near-end portion of netting that connects gradually, distal end portion of netting with near-end portion of netting draws together with the extrusion through each other middle portion of netting and then makes the diameter grow of middle portion of netting, distal end portion of netting with near-end portion of netting is through alternate segregation in order to stretch middle portion of netting and then make the diameter of middle portion of netting diminishes.
According to the utility model discloses an embodiment, keeping away from of distal end net portion the one end of middle net portion is located through setting up the cover the sliding opening of the outer wall of guide wire, with guide wire sliding fit, sliding opening is through following the axial slip of guide wire is in order to draw close or keep away from near-end net portion.
According to the utility model discloses an embodiment still includes:
the fixed catheter is sleeved on the outer wall of the guide wire, the fixed catheter penetrates through the recovery catheter, the first accommodating cavity is formed between the inner wall of the recovery catheter and the outer wall of the fixed catheter, and one end, far away from the middle net portion, of the near-end net portion is fixedly connected with one end of the fixed catheter.
According to the utility model discloses an embodiment, the inner wall of fixed pipe with the outer wall of guide wire is equipped with the second and holds the chamber, the second holds the chamber and runs through the both ends of fixed pipe, keeping away from in the second appearance chamber the one end of near-end net portion is used for infusing the medicine, the second holds being close to of chamber the one end of near-end net portion is used for exporting the medicine.
According to the utility model discloses an embodiment still includes:
the connecting handle is provided with a guide wire channel, a first channel and a second channel, the guide wire channel is used for conveying the guide wire, the first channel is used for conveying the fixed catheter, and the second channel is used for conveying the recovery catheter.
According to the utility model discloses an embodiment, connect the handle including dismantling the near-end handle and the distal end handle of connection, the seal wire passageway with first passageway is located on the near-end handle, the second passageway is located on the distal end handle.
According to the utility model discloses an embodiment, the distal end of guide wire certainly but the distal end of variable diameter thrombectomy support stretches out and is equipped with flexible pointed end.
According to an embodiment of the present invention, the density of the distal end of the variable diameter thrombectomy support is greater than the density of the proximal end thereof.
Specifically, the utility model provides a method for using of multi-functional thrombus treatment device, including following step:
controlling the diameter of the variable-diameter thrombus taking support to be smaller than that of a blood vessel, so that the guide wire penetrates into the blood vessel and penetrates through thrombus;
injecting medicine into the first cavity from one end of the first cavity close to the proximal end of the guide wire, so that the medicine is output from the distal end of the first cavity close to the guide wire and acts on thrombus to soften or decompose the thrombus;
increasing the diameter of the variable-diameter embolectomy support, so that the variable-diameter embolectomy support penetrates thrombus originally positioned on the outer side of the variable-diameter embolectomy support in the diameter increasing process and the thrombus is contained between the inner side of the variable-diameter embolectomy support after the diameter is increased and the outer side of the guide wire, and capturing the thrombus;
the recovery catheter is sleeved on the outer wall of the guide wire, and a first containing cavity is formed between the inner wall of the recovery catheter and the outer wall of the guide wire;
the variable diameter embolectomy support is of a net structure, the guide wire penetrates through the variable diameter embolectomy support, and the diameter of the variable diameter embolectomy support is variable.
Specifically, the method for using the multifunctional thrombus treatment device may further include:
under the condition that the diameter of a blood vessel at a thrombus part is larger or the gap between the blood vessel and a blood vessel wall is larger, a recovery catheter accommodating the variable-diameter thrombus taking support is inserted into the blood vessel, passes through thrombus tissues, and is withdrawn, and the guide wire naturally expands at the thrombus part to capture thrombus;
when the diameter of a blood vessel at a thrombus part is small and the recovery catheter cannot pass through, the recovery catheter accommodating the variable-diameter embolectomy stent is inserted into a part close to the thrombus part, the variable-diameter embolectomy stent is fixed to the minimum diameter, then the variable-diameter embolectomy stent under the minimum diameter is pushed out of the recovery catheter and further passes through thrombus tissues, and the stent is expanded to the maximum diameter to capture the thrombus.
Increasing the diameter of the variable-diameter embolectomy support, so that the variable-diameter embolectomy support penetrates thrombus originally positioned on the outer side of the variable-diameter embolectomy support in the diameter increasing process and the thrombus is contained between the inner side of the variable-diameter embolectomy support after the diameter is increased and the outer side of the guide wire, and capturing the thrombus; the diameter of the stent is repeatedly changed to capture the thrombus tissue to the maximum extent.
When, before or after the thrombus is captured by repeatedly changing the diameter of the stent, the medicine is injected from the near end of the first containing cavity, the second containing cavity or/and the third containing cavity, and the medicine flows out near or inside the thrombus tissue at the far end of the first containing cavity, the second containing cavity or/and the third containing cavity so as to soften or decompose the thrombus and increase the effect of capturing the thrombus by the stent.
And the variable-diameter embolectomy support is accommodated in the first containing cavity of the recovery catheter and leaves the blood vessel along with the recovery catheter.
Implement the embodiment of the utility model discloses an embodiment helps realizing following beneficial effect:
on the one hand, in the multi-functional thrombus treatment device of this embodiment, through setting up that self diameter is adjustable but the thrombus support is got to the reducing carries out the regulation of self diameter according to the not blood vessel of unidimensional to move smoothly in the not blood vessel of equidimensional, and can increase self diameter until the butt thrombus according to the size of thrombus, realize the seizure to the thrombus of equidimension not in the blood vessel.
On the other hand, through the recovery catheter which is arranged between the recovery catheter and the guide wire and forms the first containing cavity, the thrombus can be dissolved in the first containing cavity in a mode of injecting medicine into the first containing cavity, or the thrombus with larger volume is decomposed into a plurality of thrombus with smaller volume which can be captured by the thrombus-capturing stent body, or the thrombus is softened, the softened thrombus is easier to be extruded and cut by the variable-diameter thrombus-capturing stent in the diameter increasing process, the effect of capturing the thrombus by the variable-diameter thrombus-capturing stent is further improved, meanwhile, the variable-diameter thrombus-capturing stent after the thrombus is captured can be accommodated in the first containing cavity in a mode of reducing the diameter of the variable-diameter thrombus-capturing stent, then the variable-diameter thrombus-capturing stent leaves the blood vessel along with the recovery catheter, the recovery catheter plays a role in wrapping the thrombus in the variable-capturing stent, the situation that the thrombus is separated from and escapes in the process of leaving the blood vessel so as to block other branch blood vessels is avoided, and the structure is simple.
On the other hand, on the basis of the variable-diameter thrombus taking support, the density of the far end of the variable-diameter thrombus taking support is set to be higher than that of the near end of the variable-diameter thrombus taking support, so that in the process of moving thrombus, thrombus with small volume can be collected by the far end of the variable-diameter thrombus taking support after being separated from the middle of the support body, and therefore the thrombus is prevented from being separated from other branch blood vessels due to the escape condition, the structure is simple, and the using effect is good.
Drawings
In order to more clearly illustrate the technical solutions of the present invention or the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Wherein:
fig. 1 is a schematic structural view of a multifunctional thrombus treatment device according to an embodiment of the present invention;
FIG. 2 is an enlarged view of detail A of FIG. 1;
FIG. 3 is an enlarged view of detail B of FIG. 1;
FIG. 4 is an enlarged view of detail C of FIG. 1;
fig. 5 is a schematic structural diagram of the variable diameter thrombectomy support in the first state according to the embodiment of the present invention;
fig. 6 is a schematic structural view of the variable diameter thrombectomy support in the second state according to the embodiment of the present invention;
fig. 7 is a schematic structural view of the variable diameter thrombectomy support in the third state according to the embodiment of the present invention;
fig. 8 is a schematic structural view of the variable diameter thrombectomy support in the fourth state according to the embodiment of the present invention;
fig. 9 is a schematic structural view of a nozzle and a third cavity in an embodiment of the present invention;
FIG. 10 is a photograph of the multifunctional thrombus treatment device in example 1 of the present invention in the carotid artery of an animal;
reference numerals:
1. a guide wire; 11. a proximal end stop; 12. a distal stop; 13. a flexible tip; 14. a third cavity; 15. spraying a hole; 2. a recovery conduit; 21. a first cavity; 3. the diameter-variable thrombus taking support; 31. a distal net section; 32. an intermediate net section; 33. a proximal net section; 34. a slide opening; 4. fixing the catheter; 41. a second cavity; 5. a connecting handle; 51. a guidewire channel; 52. a first channel; 53. a second channel; 54. a proximal handle; 55. a distal handle; 56. a guidewire adjuster; 6. thrombosis; 7. a blood vessel.
Detailed Description
To make the objects, technical solutions and advantages of the present invention clearer, the drawings of the present invention are combined to clearly and completely describe the technical solutions of the present invention, and obviously, the described embodiments are some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
Referring to fig. 1-10, embodiments of the present invention provide a multifunctional thrombus treatment device, including:
a guide wire 1;
the recovery catheter 2 is sleeved on the outer wall of the guide wire 1, and a first containing cavity 21 is formed between the inner wall of the recovery catheter 2 and the outer wall of the guide wire 1;
but reducing thrombectomy support 3, but reducing thrombectomy support 3 is network structure, but guide wire 1 wears to locate but reducing thrombectomy support 3, but the diameter of reducing thrombectomy support 3 is changeable, but reducing thrombectomy support 3 is through changing the blood vessel 7 or the thrombus 6 of self diameter in order to be suitable for different widths, first appearance chamber 21 is used for accomodating but reducing thrombectomy support 3 is used for carrying the medicine.
Specifically, the diameter-variable thrombus-taking support 3 is movable relative to the recovery catheter 2 in position to allow the diameter-variable thrombus-taking support 3 to be accommodated in the recovery catheter 2, and it should be noted that the diameter-variable thrombus-taking support 3 is movable in the axial direction of the recovery catheter 2 to allow the diameter-variable thrombus-taking support 3 to be accommodated in the recovery catheter 2, and the diameter-variable thrombus-taking support 3 is movable in the axial direction of the diameter-variable thrombus-taking support 3 to allow the diameter-variable thrombus-taking support 3 to be accommodated in the recovery catheter 2.
All the benefits mentioned in this description can be achieved simultaneously in one operation by this embodiment.
It should be noted that, a person skilled in the art may design the outer diameter of the recovery catheter 2 to be smaller than the inner diameter of each of the blood vessels 7 to move the recovery catheter 2 in each of the blood vessels 7, or may design the outer diameter of the recovery catheter 2 to be smaller than the inner diameter of the blood vessel 7 to be acted on in a targeted manner according to the blood vessel 7 to be acted on, or may design the outer diameter of the recovery catheter 2 to be smaller than the inner diameter of the cardiovascular vessel when the multifunctional thrombus treatment device is used for treating the cardiovascular vessel, or may design the outer diameter of the recovery catheter 2 to be smaller than the inner diameter of the vena cava when the multifunctional thrombus treatment device is used for treating the vena cava thrombus.
In the multifunctional thrombus treatment device of the embodiment, the variable diameter thrombus removal stent 3 with an adjustable self diameter is arranged, the self diameter is adjusted according to the blood vessels 7 with different diameters, so as to smoothly move in the blood vessels 7 with different sizes, as shown in fig. 5, the variable diameter thrombus removal stent 3 reduces the self diameter to the minimum diameter, after the thrombus 6 passes through, the self diameter can be increased according to the size of the thrombus 6 until the thrombus 6 abuts against, so that the thrombus 6 with different sizes in the blood vessel 7 can be captured, and the variable diameter thrombus removal stent 3 is in a completely opened state structure as shown in fig. 6.
Through setting up and leading between the guide wire 1 and forming first recovery pipe 2 that holds chamber 21, the accessible on the one hand is to the mode of first appearance chamber 21 injection, realizes the dissolution to thrombus 6, decomposes thrombus 6 of great volume into a plurality of can be got the less thrombus 6 of volume of embolus support 3 seizure by the variable diameter, or softens thrombus 6, thrombus 6 after the softening is changeed in getting the extrusion cutting of embolus support 3 by the variable diameter that is in the diameter increase in-process, the effect of thrombus 6 is caught to the support 3 of getting embolus by the variable diameter has further been improved.
The variable-diameter thrombus taking support 3 after the thrombus 6 is captured can be accommodated in the first accommodating cavity 21 in a manner of reducing the diameter of the variable-diameter thrombus taking support 3, a structure shown in fig. 8 is formed, then the variable-diameter thrombus taking support leaves the blood vessel 7 along with the recovery catheter 2, the recovery catheter 2 plays a role in wrapping the thrombus 6 in the variable-diameter thrombus taking support 3, the thrombus 6 is prevented from being separated and escaping in the process that the variable-diameter thrombus taking support 3 leaves the blood vessel 7, and then the condition of blocking other branch blood vessels 7 is avoided, and the structure is simple.
As shown in fig. 2, according to the utility model discloses an embodiment, but variable diameter thrombectomy support 3 is including the distal net portion 31, middle net portion 32 and the near-end net portion 33 that connect gradually, distal net portion 31 with near-end net portion 33 is through drawing close to each other in order to extrude middle net portion 32 and then make the diameter grow of middle net portion 32, distal net portion 31 with near-end net portion 33 is through mutual separation in order to stretch middle net portion 32 and then make the diameter of middle net portion 32 diminishes.
It should be noted that the diameter of the variable diameter embolectomy stent 3, which is composed of the distal net part 31, the middle net part 32 and the proximal net part 33, can be changed by making the distal net part 31, the middle net part 32 and the proximal net part 33 telescopically, hingedly or flexibly connected between each two net parts, or the diameter of the variable diameter embolectomy stent 3 can be changed by making the materials of the distal net part 31, the middle net part 32 and the proximal net part 33 flexible.
According to an embodiment of the present invention, the far-end net portion 31 is far away from the one end of the middle net portion 32 is located through the sliding opening 34 of the outer wall of the guiding wire 1 by the setting sleeve, so as to match with the guiding wire 1 in a sliding manner, the sliding opening 34 is through following the axial sliding of the guiding wire 1 is close to or away from the near-end net portion 33.
It will be appreciated that in this embodiment, by providing the sliding opening 34 to slidably engage with the guide wire 1, the guide wire 1 can guide the movement of the distal end of the variable diameter embolectomy stent 3 to allow smooth movement, thereby allowing the variable diameter embolectomy stent 3 to be smoothly expanded or contracted.
As shown in fig. 3 and 9, according to an embodiment of the present invention, the present invention further includes:
the fixed guide tube 4 is sleeved on the outer wall of the guide wire 1, the fixed guide tube 4 penetrates through the recovery guide tube 2, the first accommodating cavity 21 is formed between the inner wall of the recovery guide tube 2 and the outer wall of the fixed guide tube 4, and one end, far away from the middle net part 32, of the near-end net part 33 is fixedly connected with one end of the fixed guide tube 4.
Specifically, the guide wire 1 is slidably fitted to the fixed catheter 4, and the guide wire 1 is relatively movable with respect to the fixed catheter 4 in the axial direction of the fixed catheter 4, the fixed catheter 4 is slidably fitted to the recovery catheter 2, and the fixed catheter 4 is relatively movable in the axial direction of the recovery catheter 2.
More specifically, as shown in fig. 2, the medical endoscope further includes a near-end limiting member 11 and a far-end limiting member 12, the near-end limiting member 11 and the far-end limiting member 12 are sleeved on the guide wire 1, and are distributed in sequence along a direction from the near end of the guide wire 1 to the far end of the guide wire 1, the fixed catheter 4 is abutted against the joint of the variable diameter embolus-taking bracket 3 through the near-end limiting member 11, so as to limit the maximum diameter of the variable diameter embolus-taking bracket 3, and the far-end limiting member 12 is abutted against the sliding opening 34, so as to limit the minimum diameter of the variable diameter embolus-taking bracket 3.
According to an embodiment of the present invention, the density of the distal end of the variable diameter thrombectomy support 3 is greater than the density of the proximal end thereof.
Through setting up the distal end density of distal end net part 31 to be greater than the density of near end net part 33, in the in-process of removing thrombus 6, the thrombus 6 that the volume is less is followed after the middle part net part breaks away from, can be collected by distal end net part 31 to avoid thrombus 6 to take place to break away from and the condition about escaping and block up other branch blood vessel 7, simple structure, excellent in use effect.
In this embodiment, when taking the embolism, but reducing thrombectomy support 3 with fixed catheter 4 passes through 6 positions on thrombus under the guide of guide wire 1 after, but release reducing thrombectomy support 3 to through adjusting distal end locating part 12 and near-end locating part 11, make but reducing thrombectomy support 3 changes repeatedly so that thrombus 6 is fully caught and gets into in the support, drags backward guide wire 1 but reducing thrombectomy support 3 and fixed catheter 4 gets into in recovery catheter 2, thrombus 6 of escaping is along with the blood flow to but reducing thrombectomy support 3 during the distal end flows, by the density great the partial net of distal end portion 31 catches to prevent the emergence of escaping.
Specifically, in this embodiment, the diameter of the variable diameter thrombectomy stent 3 can be arbitrarily and repeatedly adjusted by repeatedly pushing and pulling the guide wire 1, and the sizes of the proximal net portion 33, the distal net portion 31 and the middle net portion 32 are changed, so that the chance of capturing the thrombi 6 is increased, and the effect of the thrombectomy is enhanced.
Specifically, the usage of the distal end limiting member 12 is as follows: the guide wire 1 is pushed to enable the guide wire 1 and the fixed catheter 4 to move relatively, the guide wire 1 moves towards the far end direction, the far end limiting piece 12 is abutted to and pushes the sliding opening 34 to be far away from the fixed catheter 4, the variable diameter embolectomy support 3 is used for connecting one end of the fixed catheter 4 and one end of the variable diameter embolectomy support 3 used for connecting the sliding opening 34, the distance between the end of the variable diameter embolectomy support 3 and the end of the variable diameter embolectomy support 3 used for connecting the sliding opening 34 is increased, the diameter of the variable diameter embolectomy support 3 is reduced while the variable diameter embolectomy support 3 is stretched, the state structure shown in fig. 5 is formed, conversely, the guide wire 1 and the fixed catheter 4 move relatively, the guide wire 1 moves towards the near end direction, the variable diameter embolectomy support 3 recovers under the elastic action of the variable diameter embolectomy support 3 after losing the support of the far end limiting piece 12, namely, the diameter of the variable diameter embolectomy support 3 is increased to the diameter of the variable diameter embolectomy support 3 in the natural state, and the state structure shown in fig. 6 is formed by the variable diameter embolectomy support 3.
Understandably, the outer diameter of the distal stop 12 is larger than the inner diameter of the sliding opening 34, so that the distal stop 12 can abut against and push the sliding opening 34.
Understandably, the maximum diameter of the variable diameter embolectomy support 3 is determined by the position of the proximal end limiting part 11 on the guide wire 1, and the use mode of the proximal end limiting part 11 is as follows: when the elastic property of the variable diameter thrombectomy support 3 is not inactivated, the diameter of the variable diameter thrombectomy support 3 is maintained at a certain fixed value when the variable diameter thrombectomy support 3 is in a natural state, i.e. the distal limit piece 12 and the proximal limit piece 11 are not abutted against each other, and when the elastic property of the variable diameter thrombectomy support 3 is inactivated, or when an obstacle such as a thrombus 6 exists at the distal end of the variable diameter thrombectomy support 3 and generates a proximal relative acting force on the distal end of the variable diameter thrombectomy support 3, the diameter of the variable diameter thrombectomy support 3 may be continuously increased by the acting force until the diameter of the variable diameter thrombectomy support 3 exceeds the diameter of the variable diameter thrombectomy support 3 in the natural state, and if the diameter of the variable diameter thrombectomy support 3 is not limited, the blood vessel 7 may be squeezed due to an excessively large diameter of the variable diameter thrombectomy support 3, therefore, by providing the proximal limiting member 11, when the guiding guidewire 1 and the fixed catheter 4 move relatively and move proximally to a certain position along the axial direction of the variable diameter embolectomy support 3, the proximal limiting member 11 will abut against the distal end of the fixed catheter 4, and since the proximal limiting member 11 and the distal limiting member 12 are fixed to the guiding guidewire 1, the distance between the proximal limiting member 11 and the distal limiting member 12 is constant, and at this time, the proximal limiting member 11 cannot move proximally continuously and the distal limiting member 12 cannot move proximally, and at this time, the variable diameter embolectomy support 3 forms a state structure as shown in fig. 7, and the sliding opening 34 having a tendency to move proximally cannot move proximally due to the abutting action of the distal limiting member 12, that is, the guide wire 1 cannot move continuously towards the proximal end, thereby avoiding the diameter of the variable diameter embolectomy stent 3 from increasing continuously.
It should be noted that, only the distal end limiting member 12 may be provided to reduce the diameter of the variable diameter embolectomy support 3, and the self diameter is increased until the diameter returns to the original shape by the elasticity of the variable diameter embolectomy support 3, and the proximal end limiting member 11 is omitted, but accordingly, the beneficial effect of the proximal end limiting member 11 is lost, and meanwhile, other limiting members penetrating through the guide wire 1 may be further added at any position inside the variable diameter embolectomy support 3.
Specifically, but reducing thrombectomy support 3 is woven by shape memory materials such as nickel titanium alloy silk and forms to the effect of realization through self elastic effect reconversion, just but reducing thrombectomy support 3 still can add the weaving silk of a plurality of X-ray development, namely reducing thrombectomy support 3 is woven by a plurality of nickel titanium alloy silk and a plurality of X-ray development weaving silk and forms, and understandably, nickel titanium alloy silk can be one or many, and X-ray development weaving silk also can be one or many.
More specifically, the proximal end limiting part 11 and the distal end limiting part 12 are provided with developing materials, and the whole process of the embolectomy process is visible through the developing weaving wire and the developing bracket straight-through adjusting ring.
Understandably, in this embodiment, the outer diameter of the guiding wire 1 is smaller than the inner diameter of the fixing catheter 4, the outer diameter of the fixing catheter 4 is smaller than the inner diameter of the recovery catheter 2, the guiding wire 1 is inserted into the fixing catheter 4, the fixing catheter 4 is inserted into the recovery catheter 2, in an initial state, the variable-diameter embolectomy stent 3 is integrally contained in the recovery catheter 2, and at least part of the guiding wire 1 penetrates out of the recovery catheter 2 from the distal end of the fixing catheter 4.
The embodiment has at least two use modes, in the first use mode, the recovery catheter 2 is in a fixed state, the guide wire 1 and the fixed catheter 4 move together, and the diameter-variable embolectomy stent 3 can be driven to extend out of the distal end of the recovery catheter 2 or retract into the recovery catheter 2;
in the second usage mode, the recovery catheter 2 and the fixed catheter 4 are fixed, at this time, the near end of the variable diameter embolectomy support 3 (i.e. the connecting position of the variable diameter embolectomy support 3 and the fixed catheter 4) is in a fixed state, the guide wire 1 slides relative to the fixed catheter 4 and drives the movement of the variable diameter embolectomy support 3, so that the variable diameter embolectomy support 3 can be driven to expand or contract, the variable diameter embolectomy support 3 can correspond to the internal structure of the blood vessel 7 and/or the structure of the thrombus 6, and actions such as cutting, scraping and contracting are realized.
In addition, guide wire 1 in this embodiment, fixed pipe 4 sets up to the structure that cup joints in proper order with retrieving pipe 2, can make guide wire 1 get to tie support 3 and all hold in retrieving pipe 2 with variable footpath, get to tie support 3 by guide wire 1, the footpath, the overall structure of the pipe bracket component that fixed pipe 4 and recovery pipe 2 constitute is more compact, in operation process, just need not to set up other seal wires separately, not only can reduce the volume of taking to tie and keeping the equipment in patient's health among the operation process, with the injury that reduces and lead to the fact patient's health, can also be convenient for pipe bracket component's transportation and use, the time of clinical intervention operation has greatly been simplified, excellent in use effect.
According to the utility model discloses an embodiment, the inner wall of fixed pipe 4 with the outer wall of guide wire 1 is equipped with the second and holds chamber 41, the second holds chamber 41 and runs through the both ends of fixed pipe 4, keeping away from of chamber 41 the one end of near-end net portion 33 is used for injecting into the medicine to make the medicine that injects follow chamber 41 is close to the second the one end output of near-end net portion 33 to further improve the thrombolytic effect.
Specifically, the outer wall of the fixed catheter 4 may further be provided with a plurality of drug administration holes, and the plurality of drug administration holes are disposed at positions close to the distal end of the fixed catheter 4; with the arrangement, when the thrombolytic drug liquid is conveyed through the fixed catheter 4, the drug liquid can be diffused through the Shi Yaokong, so that the drug application range of the drug liquid is improved, and the using effect is good.
As shown in fig. 4, according to an embodiment of the present invention, further comprising:
the device comprises a connecting handle 5, wherein a guide wire channel 51, a first channel 52 and a second channel 53 are formed in the connecting handle 5, the guide wire channel 51 is used for conveying the guide wire 1, the first channel 52 is used for conveying the fixed catheter 4, and the second channel 53 is used for conveying the recovery catheter 2.
It can be understood that, in the present embodiment, by providing the above-mentioned connection handle 5, the guiding wire 1, the fixing catheter 4 and the recovery catheter 2 can be controlled to be delivered through the guiding wire channel 51, the first channel 52 and the second channel 53, respectively, so as to achieve embolectomy, which is compact and easy to operate, and meanwhile, the thrombolytic or other therapeutic drugs are injected into the third cavity 14, the second cavity 41 and the first cavity 21 through the guiding wire channel 51, the first channel 52 and the second channel 53, respectively.
Specifically, the first channel 52 and the second channel 53 are both tee pipes, one nozzle of the first channel 52 is suitable for being communicated with the guide wire channel 51 and guiding the guide wire 1 to pass in, the other nozzle is suitable for fixing the guide pipe 4 to pass in, the third nozzle is suitable for being communicated with one nozzle of the second channel 53 and fixing the guide pipe 4 to pass out, the third nozzle is also suitable for injecting thrombolytic drugs or other therapeutic drugs, the other nozzle of the second channel 53 is suitable for recovering the guide pipe 2 to pass in or injecting thrombolytic drugs or other therapeutic drugs, and the third nozzle is suitable for recovering the guide pipe 2 to pass out.
According to an embodiment of the present invention, the connection handle 5 comprises a proximal handle 54 and a distal handle 55, which are detachably connected, the guide wire channel 51 and the first channel 52 are provided on the proximal handle 54, and the second channel 53 is provided on the distal handle 55.
Through the arrangement of the detachably connected proximal handle 54 and the distal handle 55, in the use process, the proximal handle 54 and the distal handle 55 with corresponding structures can be selected and combined according to actual surgical requirements, and the distal handle 55 can be further provided with a third channel, a fourth channel and the like to realize corresponding functions, which is not limited uniquely herein.
Specifically, the connection handle 5 is further provided with a guide wire adjusting member 56, the guide wire 1 is inserted into the guide wire adjusting member 56, and the guide wire adjusting member 56 is used for driving the guide wire 1 to move relative to the connection handle 5, and more specifically, an external thread which is in threaded fit with the guide wire adjusting member 56 is arranged on the peripheral side of the guide wire 1, so that the purpose that the guide wire 1 moves relative to the connection handle 5 can be achieved by rotating the guide wire adjusting member 56.
More specifically, in the present embodiment, the extending direction of the first channel 52 and the extending direction of the guide wire channel 51 have an angle therebetween, and the first channel 52 is inclined toward the direction close to the proximal end of the connection handle 5; the second channel 53 also extends at an angle to the guide wire channel 51, and the second channel 53 is inclined towards the proximal end of the connection handle 5; from this setting, connecting handle 5 whole forms Y type structure, not only can improve fixed pipe 4 and retrieve pipe 2's transport resistance, avoids blockking up and buckles, and in the use, medical personnel only need to grip connecting handle 5 and can operate guide wire 1, fixed pipe 4 and retrieve pipe 2 respectively, and it is convenient to use.
According to an embodiment of the present invention, the distal end of the guide wire 1 extends from the distal end of the variable diameter thrombectomy support 3 and is provided with a flexible tip 13.
With this arrangement, when the guide wire 1 is inserted into the blood vessel 7, the flexible tip 13 can deform when touching the inner wall of the blood vessel 7 or an obstacle in the blood vessel 7, so as to avoid puncture injury to the inner wall of the blood vessel 7.
Specifically, a third cavity 14 penetrating through two ends of the guide wire 1 is arranged inside the guide wire 1, the guide wire 1 is provided with a nozzle hole 15 for communicating the third cavity 14 with the outside of the guide wire 1, and a drug is injected into the third cavity 14 from the proximal end of the guide wire 1 so as to be output to the outside of the guide wire 1 through the nozzle hole 15.
More specifically, one end of the jet hole 15 for outputting the medicine to the outside of the guide wire 1 faces the variable diameter embolectomy stent 3.
The utility model provides a use method of a multifunctional thrombus treatment device, which comprises the following steps:
controlling the diameter of the variable-diameter embolectomy stent 3 to be smaller than that of a blood vessel 7, so that the guide wire 1 penetrates into the blood vessel 7 and the guide wire 1 penetrates through a thrombus 6;
injecting a medicine into the first cavity 21 from one end of the first cavity 21 close to the proximal end of the guide wire 1, so that the medicine is output from the distal end of the first cavity 21 close to the guide wire 1 and acts on the thrombus 6 to soften or decompose the thrombus 6;
increasing the diameter of the variable-diameter thrombus extraction support 3, so that the variable-diameter thrombus extraction support 3 penetrates through the thrombus 6 originally positioned on the outer side of the variable-diameter thrombus extraction support 3 in the diameter increasing process, and the thrombus 6 is accommodated between the inner side of the variable-diameter thrombus extraction support 3 after the diameter is increased and the outer side of the guide wire 1, thereby realizing the capture of the thrombus 6;
specifically, the diameter of the variable-diameter embolectomy support 3 is increased, so that the variable-diameter embolectomy support 3 penetrates through the thrombus 6 originally positioned on the outer side of the variable-diameter embolectomy support 3 in the diameter increasing process, and the thrombus 6 is accommodated between the inner side of the variable-diameter embolectomy support 3 with the increased diameter and the outer side of the guide wire 1, and the thrombus 6 is captured;
simultaneously with, before or after the thrombus is captured by repeatedly changing the diameter of the stent, the medicine is injected from the proximal end of the first cavity 21, the second cavity 41 and/or the third cavity 14, and flows out from the distal end of the first cavity 21, the second cavity 41 and/or the third cavity 14 near or inside the thrombus tissue 6 so as to soften or decompose the thrombus 6 and increase the effect of capturing the thrombus by the stent.
Example 1: the multifunctional thrombus treatment device of the utility model is produced according to the figure 1. The produced variable-diameter thrombus taking stent 3 is implanted into the carotid artery of a pig. Under an X-ray machine, the diameter-variable thrombus taking support 3 prepared by the developing wire and the near-end limiting piece 11 and the far-end limiting piece 12 on the guide wire 1 of the multifunctional thrombus treatment device are clearly visible, the guide wire 1 is pushed and pulled, and the diameter-variable thrombus taking support 3 can freely change in the carotid artery. The guide wire 1 is unfolded, and the diameter-variable thrombus taking support 3 can be easily collected into the recovery catheter 2. Fig. 10 is an image of a variable diameter embolectomy stent 3 in the porcine carotid artery.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of an embodiment of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.

Claims (9)

1. A multi-functional thrombus treatment device, comprising:
a guide wire (1);
the recovery catheter (2) is sleeved on the outer wall of the guide wire (1);
the variable-diameter thrombus taking support (3) is of a net structure, and the guide wire (1) penetrates through the variable-diameter thrombus taking support (3);
the guide wire guiding device comprises a fixed catheter (4), wherein the fixed catheter (4) is sleeved on the outer wall of the guide wire (1), the fixed catheter (4) penetrates through the recovery catheter (2), and a first containing cavity (21) is formed between the inner wall of the recovery catheter (2) and the outer wall of the fixed catheter (4).
2. The multifunctional thrombus treatment device according to claim 1, wherein the variable diameter thrombus removal stent (3) comprises a distal net part (31), a middle net part (32) and a proximal net part (33) which are connected in sequence.
3. The multifunctional thrombus treatment device according to claim 2, wherein an end of the distal net portion (31) far from the intermediate net portion (32) is slidably fitted with the guide wire (1) by providing a slide opening (34) sleeved on an outer wall of the guide wire (1).
4. The multifunctional thrombus treatment device according to claim 3, wherein an end of the proximal net section (33) remote from the intermediate net section (32) is fixedly connected to an end of the fixing catheter (4).
5. The multifunctional thrombus treatment device according to claim 4, wherein a second cavity (41) is formed on the inner wall of the fixing catheter (4) and the outer wall of the guide wire (1), and the second cavity (41) penetrates through two ends of the fixing catheter (4).
6. The multifunctional thrombus treatment device according to claim 5, further comprising:
the device comprises a connecting handle (5), wherein a guide wire channel (51), a first channel (52) and a second channel (53) are formed in the connecting handle (5), the guide wire channel (51) is used for conveying the guide wire (1), the first channel (52) is used for conveying the fixing catheter (4), and the second channel (53) is used for conveying the recovery catheter (2).
7. The multifunctional thrombus treatment device according to claim 6, wherein the connection handle (5) comprises a proximal handle (54) and a distal handle (55) which are detachably connected, the guide wire channel (51) and the first channel (52) are provided on the proximal handle (54), and the second channel (53) is provided on the distal handle (55).
8. The multifunctional thrombus treatment device according to claim 1, wherein the distal end of the guide wire (1) extends from the distal end of the variable diameter embolectomy stent (3) and is provided with a flexible tip (13).
9. The multifunctional thrombus treatment device according to claim 1, wherein the density of the variable diameter thrombus removal stent (3) at the distal end is greater than that at the proximal end.
CN202220040764.3U 2022-01-07 2022-01-07 Multifunctional thrombus treatment device Active CN217793233U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114391921A (en) * 2022-01-07 2022-04-26 东莞天天向上医疗科技有限公司 Multifunctional thrombus treatment device and use method thereof
CN116269651A (en) * 2022-12-06 2023-06-23 杭州亿科医疗科技有限公司 Prevent that thrombus extraction net from releasing in advance's thrombus extraction device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114391921A (en) * 2022-01-07 2022-04-26 东莞天天向上医疗科技有限公司 Multifunctional thrombus treatment device and use method thereof
CN114391921B (en) * 2022-01-07 2023-12-26 东莞天天向上医疗科技有限公司 Multifunctional thrombus treatment device and application method thereof
CN116269651A (en) * 2022-12-06 2023-06-23 杭州亿科医疗科技有限公司 Prevent that thrombus extraction net from releasing in advance's thrombus extraction device
CN116269651B (en) * 2022-12-06 2023-10-10 杭州亿科医疗科技有限公司 Prevent that thrombus extraction net from releasing in advance's thrombus extraction device

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