CN203379185U - Intracranial thrombus removing device - Google Patents

Intracranial thrombus removing device Download PDF

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Publication number
CN203379185U
CN203379185U CN201320317548.XU CN201320317548U CN203379185U CN 203379185 U CN203379185 U CN 203379185U CN 201320317548 U CN201320317548 U CN 201320317548U CN 203379185 U CN203379185 U CN 203379185U
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China
Prior art keywords
withdrawing device
getting
hypotube
intracranial
bolt support
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CN201320317548.XU
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Chinese (zh)
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孙永全
金飞龙
叶萍
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Achieva Medical (Shanghai) Co Ltd
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Achieva Medical (Shanghai) Co Ltd
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Abstract

The utility model discloses an intracranial thrombus removing device, and belongs to the field of medical instruments. The intracranial thrombus removing device comprises a thrombus removing system, a conveying and releasing system and a handle system. The thrombus removing system comprises a self-expanding thrombus removing stent which is of a tubular or cage-shaped structure; the conveying and releasing system comprises a slim hollow conveying wavy pipe and a development ring, the development ring is connected with the thrombus removing stent and the conveying wavy pipe, a releasing traction fiber longitudinally advances, withdraws and slides in an inner cavity of a pipeline of the conveying wavy pipe, and a distal end of the releasing traction fiber is movably connected with a distal end of the thrombus removing stent in a releasing pipe and closes the distal end of the thrombus removing stent; the handle system comprises a handle, a push button and a rotatable locking valve; a part of the thrombus removing stent and a part of the conveying and releasing system are accommodated in a guide sheath. The intracranial thrombus removing device has the advantages that the intracranial thrombus removing device is convenient to operate and accurate and reliable in thrombus removing, blood vessel walls and surrounding blood vessels of a patient is rarely injured by the intracranial thrombus removing device, and the distal end of the thrombus removing stent can is closed and accordingly prevent large thrombi from blocking distal-end blood vessels of the patient; the closed distal end can be opened as needed, so that the intracranial thrombus removing device can be used as a blood flow remodeling device.

Description

The Intracranial thrombus withdrawing device
technical field
This utility model relates to a kind of medical apparatus and instruments, in particular, this utility model relates to a kind of for when patients acuity cerebral infarction (acute ischemic stroke) is fallen ill, and eliminates the thrombosis that is blocked in intracranial vessel by mechanicalness to reach the Intracranial thrombus withdrawing device of the therapeutic purposes of recovering blood flow.
background technology
In China, acute apoplexy (acute stroke) is to cause dead the third-largest reason and first of disabling.According to statistics, the annual new apoplexy in the whole nation is 2,000,000 people approximately, the person that dies from the apoplexy every year is 1,500,000 people approximately, the apoplexy survivor is 6,500,000 people approximately, the direct cost that the whole nation is used for the treatment of apoplexy every year surpasses 20,000,000,000 yuan, and wherein Ischemic Stroke (ischemic stroke) accounts for 85% of all patients.And, in the U.S., the new patients with cerebral apoplexy of 25-50 ten thousand is arranged every year, and wherein surpass 150,000 people's death, according to U.S. American Heart Association statistics, the whole America has patients with cerebral apoplexy 3,000,000 people.Once cerebral infarction occurs, must within the shortest time, (effective time window) launch treatment, can eliminate by the pharmacological elimination of thromboembolism and the machinery of thromboembolism.Pharmacological elimination can be by intravenous injection rt-PA(tissue-type plasminogen activator) or urokinase with thrombus, also can pass through intra-arterial contact thrombolysis, antiplatelet aggregation and anticoagulant treatment etc.Although having demonstrated, thromboembolism treatment can improve preferably neurological outcome, but, the medicine thrombolytic still faces some problem demanding prompt solutions, at first be that the thrombolytic time window is short, the state-run sacred disease of the U.S. and apoplexy institute (The National Institute Neurological Disorders and Stroke rt-PA Stroke Study Group, NINDS) research is thought, intravenous thrombolysis should be carried out within 3 hours in morbidity, tremulous pulse thrombolytic time window should be within 6 hours, and so short thrombolytic time window causes the patient who only has 4.5%-6.3% can accept thromboembolism treatment, secondly, the revascularization time of medicine thrombolytic is long, and the revascularization time may be one of key factor affected clinical prognosis, and no matter is intravenous thrombolysis or tremulous pulse thrombolytic, and the revascularization time at least needs 1-2 hour, and some patients are not suitable for thromboembolism treatment.In order to solve the problem of said medicine thrombolytic, the method that machinery is eliminated thromboembolism (Mechanical Thrombectomy Device) has become study hotspot in recent years.In the prior art, use following machinery to get pin device, take and take out the endovascular thrombosis of Ischemic Stroke: the patent of invention that is CN 101340849 A in the disclosed patent No. of China " for remove the device of thrombosis from blood vessel ", by a cage shape or tubular structure by an income of the distal member with the fiber radially outward stretched out wherein, and under the help of fiber from the elimination thrombosis of safety in blood vessel.In the patent of invention that is CN 101396295 A in the disclosed patent No. of China " Intravascular Thrombus and embolus resectoscope "; thrombectomy device and the basket that is contraction or release conditions with a thrombectomby spring; basket is positioned at the far-end of thrombectomy device; thrombosis is arrested in winding by the thrombectomby spring, and will get the clot produced in the bolt process with basket and take out to protect the far-end of blood vessel together with the thrombosis fragment.In the patent of invention " endovascular thrombosis grabber " that the patent No. of announcing in China is CN 102316809 A, there is the line main body of haunting freely and the thrombosis of being located at its front end and catch section, by the motion that is erected at the elastica circle body between fixed part and movable part, to catch, remove the thrombosis that is attached to blood vessel wall.The patent of invention that is CN 101035474 A in the disclosed patent No. of China " for the device of removal of thromboses ", there is the guide wire that a far-end is equipped with the fiber component of an orthohormbic structure, by the motion before and after it, take out foreign body and thrombosis from body cavity and blood vessel.The patent of invention " for the method and apparatus of restoration of blood flow " that the patent No. of announcing in China is CN 102014772 A, the cancellated parts by interconnective line or filament or pillar with taper overlay structure of a self expandable, self expandable is to recover blood flow by microtubular and after pushing wire and being introduced into occluding vascular.In the patent of invention that is CN 101027004 A in the disclosed patent No. of China " system and method that is used for the treatment of cerebral infarction ", there is guiding and occlusion catheter, conveying and draw catheter, lift suction pump, thromboembolic receiver and thromboembolic separator, lift suction pump is drawn into thrombosis in thromboembolic receiver by draw catheter, thereby withdraws from external.During the utility model that the patent No. of announcing in China is ZL 200620164685.4 " is got the bolt device ", umbrella with three-jaw short by two length one of elastic memory function, the net of having with periphery forms the pin device of getting of a circular configuration, by drawing push-pull bar three-jaw is closed up and the thrombosis pocket is recovered in trocar sheath in umbrella section outward, thrombosis is taken out.In the patent of invention that is US 7931659 B2 in the disclosed patent No. of the U.S. " System and Method for Treating Ischemic Stroke ", have one be fixed on an elongated extension tube end surround into the receptor of hollow tubular by many filaments, by extension tube, receptor is placed in to the blood vessel embolism position, and thrombosis is taken in to the intracavity of receptor hollow and taken out external.In the patent of invention " Clot Retriever Device " that the patent No. of announcing in the U.S. is US 2006/0047286 A1, there is a recovery basket of expanding and shrinking that is fixed in the pusher end, on it, have one can control open and close uncovered in order to thrombosis is caught in basket by the tinsel that is fixed on the basket end.In the patent of invention " Clot Retriever Device " that the patent No. of announcing in the U.S. is US 2002/0049452 A1, have one or more be fixed on slender conduit can be in compression element the movable latch of getting that has shape memory, after being transported to the thromboembolism position by slender conduit, get in latch outwards opens thrombosis is caught and is wrapped in.In the patent of invention " Clot Retrieval Mechanism " that the patent No. of announcing in the U.S. is US 2009/0240238 A1, but there is snare and an attached to it folding sack of being made by flexible pore-free material that is fixed in the self-expanding of a slender axles end, to install along the body internal channel and be placed in the thromboembolism position by slender axles, open sack by the thrombosis bag in the inner.In the patent of invention that the disclosed patent No. of WIPO is WO 2012/065748 A1 " Thrombectomy Device ", there is a pin device of getting that is similar to rack form formed by many grids be fixed on a guide wire, on it, have pair of connectors with together with spiral type spiral in the crack of side, after by guide wire, device being delivered to the thromboembolism position, by support, thrombosis is taken out.The patent of invention that the disclosed patent No. of WIPO is WO 2009/105710 A1 " Methods and Apparatus for Flow Restoration " is separately arranged, the patent families of the patent of invention " for the method and apparatus of restoration of blood flow " that the patent No. that is the announcement of above-described China is CN 102014772 A, no longer repeat to set forth.When actual clinical is used, for the mechanical embolectomy that occurs in the arteriocerebral Ischemic Stroke such as middle cerebral artery and vertebra basilar artery, all be based on the interventional technique through the chamber blood vessel of conduit.At computer-controlled digital subtraction angiography (Digital Subtraction Angiography, DSA) under the support of system, after femoral artery puncture, microtubular is delivered to the thromboembolism position together with getting the bolt apparatus, launch basket or web frame, can remove in patient body in order to capture or surround thromboembolism; Perhaps, some examples described in above-mentioned patent documentation, be advanced to the thromboembolism place by suction pipe, by negative pressure absorbing, the thromboembolism suction catheter removed; Again or, the application laser thrombolysis device, be crushed to molecule by thrombosis, makes it smoothly by microcirculation and dissolved by the human body natural.Although these above-mentioned apparatuses have overcome the defect of pharmacological treatment, have significantly improved recanalization rate, improved clinical prognosis, reduced the incidence rate that cerebral hemorrhage transforms simultaneously, and, owing to being machinery is got bolt, greatly shortened and passed through again journey, reduced operating time, thereby striven for the more time for reversible ischemic tissue of brain, said in a sense, extended the therapeutic time window of Ischemic Stroke, thereby can make more patients be benefited.But, its open defect is, in the situation that can't look at thrombosis straight, the catching device of basket or net form formula often can not entangle blood clot and cause getting the bolt failure, and its volume is often excessive, in the cerebral arterieies such as middle cerebral artery M1 that can't be thinner at blood vessel diameter, M2 section, use; Although the mode of negative pressure absorbing is safe, but remove by absorption, only the thromboembolism to relatively soft is effective, in order to strengthen drawing effect, adopted the cracked thrombosis of rotating blade or resectoscope, although this rotating blade part has improved the effect of this aspiration technique, greatly increased the risk that blood vessel wall is caused to damage; Although laser and ultrasound wave are to clean and the effective energy, as misoperation, very easily peripheral vessels is caused to damage, and energy is too low invalid, too high injured blood vessel, therefore giving how high-octane laser intensity just can reach optimum curative effect, need further research; The pin device far-end of getting of supporting structure is open structure, and the thrombosis fragment produced in operation process is very easily escaped and stops up thinner blood vessel and the perforating branches blood vessel of far-end from far-end, causes blood vessel thromboembolism again.And, in actual clinical, the thrombosis that some is comparatively obstinate also can't be removed fully after repeatedly getting the bolt operation, now need to free and be placed in thromboembolism and sentence and make blood flow unimpeded getting pin device.From above discussion, get pin device in above-mentioned patent documentation, and other technologies of the prior art, all having one or more defects and being realized for the treatment Ischemic Stroke is suboptimum, this utility model is directed to the shortcoming that overcomes or at least improve prior art.
summary of the invention
In order to solve above-mentioned technical problem, the purpose of this utility model is to provide a kind of Intracranial thrombus withdrawing device, there is following characteristics: easy to operate, get bolt accurately and reliably, little to blood vessel wall and Peripheral Vascular Injuries, get the sealing of bolt rack far end and can prevent large Thromboembolus escape obstruction distal vessels, when decontroling the far-end of sealing whenever necessary, and keep somewhere in blood vessel as the blood flow remodeling device after electrolysis is de-.
To achieve the above object, this utility model has adopted following technical scheme: a kind of Intracranial thrombus withdrawing device comprises getting tying system, carry and free system, handle system and guide sheath pipe.Described get tie turnkey draw together the far-end of a self-expanding can seal also can be by tubulose open when bearing predetermined pull or cage structure get the bolt support; Described conveying and the system of freeing comprise the conveying hypotube of an elongated hollow, with a traction fiber of freeing of at its inner cavity of pipe, longitudinally advancing and retreat and sliding, freeing the ball of traction fiber far-end crosses the protruding ball of getting the bolt rack far end and takes in together the active connection of formation in releasing tube, described developing ring makes to get the far-end sealing of bolt support, together with will be got the bolt support and the conveying hypotube is rigidly connected to; Described handle system comprises handle and the push button that a hands grips, and the valve of a rotatable locking; Described guide sheath pipe is taken in the described part of getting bolt support and conveying and freeing system wherein; Under the external stress applied by microtubular, be folded in microtubular with getting the bolt support level and be transported to the distally of thromboembolism position, when microtubular withdraws along proximal direction, while causing external stress to disappear, get the self-expanding of bolt support and be deployed into complete tubulose or cage structure, and captive thrombosis is included in to the interior intracavity of its hollow.Subsequently, comprise the further proximad retraction of this utility model device and microtubular until it finally is contained in guiding catheter, then from vascular system, remove described guiding catheter.In this mode, can realize that especially from little inner chamber blood vessel, carrying out efficient and safe thrombosis removes.Usually, so-called guiding catheter, it has the internal diameter larger than the microtubular for placing this utility model device.Like this, all thrombosis and the bolt support of getting in its swelling state can move and be placed in guiding catheter.During treating, microtubular is also pushed ahead by guiding catheter usually, and the thromboembolism position although described guiding catheter can be pushed ahead in especially little blood vessel, especially, in the intracranial zone, can only utilize the microtubular that diameter is very little at inner chamber.In terms of the present utility model, " far-end " and " near-end " is appreciated that from the doctor in charge's direction and observes.Therefore far-end is the side away from the doctor in charge, and it relates to the parts of this utility model device be advanced to further in vascular system, and near-end means towards the doctor in charge, that is, the nearside arrangement component of device is introduced in blood vessel not far.If phrase " longitudinal direction " is used in this document, it is to be understood as the direction that means that this utility model device is pushed into, that is, the longitudinal axis of the blood vessel that the longitudinal axis of device also moves forward along it with device overlaps.In technique scheme, get the bolt rack far end and be provided with at least two cantilevers of can the elasticity bending and expanding, described cantilever is provided with protruding ball, and this protruding ball is buckled mutually with the ball of freeing the traction fiber far-end, with after a part of bending of cantilever together with take in releasing tube, form active the connection.The purpose that this activity connects, the one, in order to seal the far-end of getting the bolt support, thereby can prevent Thromboembolus escape obstruction distal vessels large in getting the bolt process; The 2nd, can free traction fiber and remove this connections by pulling when needed for convenient, make to get the far-end opening of bolt support sealing.Although from general significance to get bolt operation, the bolt of getting of 4-5 time operates and can remove inaccessible thrombosis fully, thrombosis in particular cases at some, firmly be bonded on the current-carrying blood vessel wall, is very difficult to removing.Now, need the open far-end that get the bolt support, and electrolysis keeps somewhere in body support after de-to use as the blood flow remodeling device.Remove active the connection, open closed distal end of getting the bolt support, need to use handle system.By carrying hypotube, together with freeing traction fiber, insert in the hole of rotational lock valve, and the lock valve that turns clockwise will be carried hypotube locking, stretch out the conveying hypotube owing to freeing the traction fiber near-end, its section of stretching out is locked on push button in handle inside, proximad pulls push button, make to free traction fiber with respect to carrying the hypotube proximad to slide, thereby make the ball on it cross protruding ball and drive releasing tube proximad slip together, when surpassing predetermined pull, protruding ball is deviate from from releasing tube, and cantilever will expand automatically owing to having elasticity, thereby remove the far-end of getting the sealing of bolt support.As preferably, describedly to get the bolt support particularly nitinol is via being cut into by shape-memory material, its interconnective muscle forms a plurality of unit grids.Generally speaking, tubulose or cage structure have Long Circle under swelling state, length range between 5 to 50mm and diameter between 2 to 6mm.Expansion when tubulose or cage structure are designed such that on the whole outside moving to microtubular and collapsing in being retracted into microtubular the time are folding can with no difficulty the completing of milli.As preferably, the described far-end of getting the bolt support is connected respectively and has not label releasing tube and the developing ring of Transmission X ray with near-end.The label releasing tube of described not Transmission X ray and developing ring are made by platinumiridio or platinum-tungsten alloys or platinoiridita tungsten alloy.The not Transmission X radiographic marker thing of the type makes the doctor in charge to monitor location relative to each other and therapeutic advance thus by means of the formation method that contributes to this purpose (such as DSA mentioned above etc.).As preferably, described conveying hypotube is made by the stainless steel metal pipe of elongated hollow.Should be appreciated that in order to expect purpose, carry the far-end of hypotube, especially enter the intracranial vessel section, must there is enough rigidity, but necessary enough pliable and tough or flexibles of while make them can pass microtubular and guiding catheter, and can not damage blood vessel wall.Therefore, carry the far-end of hypotube to be pruned half so that its pliability is better.As preferably, but form the de-zone of electrolysis between described conveying hypotube far-end and developing ring, can after energising, fuse and make to get the bolt support and keep somewhere in the thromboembolism position, thereby make restoration of blood flow unobstructed.As understood by the skilled person, under the effect of special-purpose electric reliever, adopt 1mA, the 3V unidirectional current, the stainless part be exposed in blood can fusing in half a minute arrives several minutes.As preferably, the described traction fiber of freeing is made by pliable and tough elongated metal wire, and its length should be able to guarantee that near-end exposes the near-end of carrying hypotube.As preferably, described guide sheath pipe is made by the polymeric material politef, its inner chamber and length dimension should be able to guarantee that the flexible portion that will get bolt support and conveying and free system takes in, and its exocoel size should be able to guarantee to push in the female Luer endoporus of microtubular.As preferably, describedly keep somewhere getting the bolt rack surface and can be coated with anticoagulant or antiplatelet drug in the thromboembolism position.As preferably, described activity is connected to while bearing over predetermined pull and lost efficacy.Described predetermined pull is set to change between 10N to 20N, its numerical value should be both not quite to making to pull too difficulty, be unlikely to again too little and this activity be connected in delivery process lost efficacy.As preferably, described developing ring is by clamping, bonding, and the mode of welding or welding or welding and welding will be got the bolt support and be carried linking together of hypotube rigidity.Described rigid connecting relay should be greater than the active predetermined inefficacy pulling force connected, and being rigidly connected of developing ring place can not be lost efficacy before active Joint failure.As preferably, described conveying hypotube and the length of freeing traction fiber should be able to guarantee this utility model device is delivered to the distally of the thrombosis of thromboembolism.
Compared with prior art, advantage of the present utility model with good effect is: by the protruding ball that will get the bolt rack far end and the ball of freeing traction fiber, be accommodated in together in releasing tube and form the active far-end sealing that makes to get the bolt support that is connected, when needed, can free traction fiber and remove this connection and make to get the bolt support and reopen by pulling again, make this utility model device have sealing and open advantage concurrently.And be connected in the not label of Transmission X ray that has of getting bolt support two ends, make to get bolt can operate visually under the support of digital subtraction angiography system, and make to get bolt accurately and reliably.Only advancing and withdraw this utility model device just can complete and get bolt operation, with traditional bolt operation of getting, compare, operation process has been greatly simplified, and has both alleviated doctor's workload, again for the patient gets valuable treatment time, for the more time has been striven in reversible ischemic tissue of brain treatment.Especially, when having special circumstances to cause thrombosis to be difficult to remove fully, can open the far-end of getting bolt support sealing, and keep somewhere in blood vessel the use as the blood flow remodeling device after electrolysis is de-.
the accompanying drawing explanation
The structural representation of the Intracranial thrombus withdrawing device that Fig. 1 is this utility model embodiment;
Fig. 2 gets pin device to be accommodated in the viewgraph of cross-section in the guide sheath pipe;
Fig. 3 is the axonometric chart of getting the bolt support;
Fig. 4 is the flat deployable structure figure that gets the bolt support;
The axonometric chart that Fig. 5 is the development turn;
The structural representation that Fig. 6 is developing ring;
Fig. 7 is for carrying the generalized section of hypotube;
Fig. 8 is the structural representation of freeing traction fiber;
The cross section view that Fig. 9 is heat-shrink tube;
The cross section view that Figure 10 is the guide sheath pipe;
The perspective view that Figure 11 is handle;
Figure 12 gets the bolt support and carries the schematic diagram of the annexation of hypotube for explanation;
Figure 13 is the schematic diagram of getting the bolt support and freeing the annexation of traction fiber for explanation;
The perspective view that Figure 14 is releasing tube;
Figure 15 treats for explanation the blood vessel of the current-carrying by the thrombosis obturation schematic diagram that this utility model device is processed;
Figure 16 is for illustrating that the Intracranial thrombus withdrawing device enters the schematic diagram in microtubular by the rotation haemostatic valve;
Figure 17,18, the 19th, take out the process schematic diagram of inaccessible thrombosis for this utility model is described;
Figure 20 gets after bolt is processed through this utility model device the schematic diagram that recovers blood flow for explanation;
Figure 21 is in particular cases device implantation schematic diagram of the present utility model is described;
Figure 22 is for the schematic diagram of the rear restoration of blood flow of device implantation of the present utility model is described;
the specific embodiment
Below in conjunction with accompanying drawing, the specific embodiment of the present utility model is made a detailed explanation:
A kind of Intracranial thrombus withdrawing device as shown in Fig. 1, comprise getting tying system 100, carry and free system 200 and handle system 300.Described get tie turnkey draw together the far-end of a self-expanding can seal also can be by tubulose open when bearing predetermined pull or cage structure get bolt support 110, carry and free the conveying hypotube 210 that system 200 comprises an elongated hollow, be fixed on the development turn 220 of carrying the not Transmission X ray in hypotube 210 distal slot, connect and get bolt support 110 and the developing ring 230 of carrying hypotube 210, far-end with get bolt support 110 far-ends and form and active be connected and its sealing freed to traction fiber 240, take in and get the protruding ball 115 of bolt support 110 far-end and free the active releasing tube 250 be connected of traction fiber 240 far-end balls 241 formation, pyrocondensation insulation and add the heat-shrink tube 260 of strong hardness effect in carrying hypotube 210 far-end outer walls, and the described bolt support 110 of getting is taken in to guide sheath pipe 270 wherein with the part of carrying hypotube 210, described handle system 300 comprises handle 310 that hands grips, pulls and free traction fiber 240 to remove the active push button 320 connected, and the rotational lock valve 330 of hypotube 210 near-ends is carried in locking.Get bolt operation most, do not need to free described active the connection with handle system 300, only have and work as some in particular cases, thrombosis firmly is bonded on the current-carrying blood vessel wall, be very difficult to remove, just need to use handle system 300 to pull and free traction fiber 240 with the open far-end of getting 110 sealings of bolt support, and electrolysis will be got bolt support 110 after de-and be kept somewhere in body and use as the blood flow remodeling device.As shown in Fig. 2, for this utility model device is accommodated in the viewgraph of cross-section in guide sheath pipe 270.Generally speaking, every cover Intracranial thrombus withdrawing device is an independent packaging, gets bolt support 110 and folded in advance and be accommodated in guide sheath pipe 270 when the supply of material, in order to avoid impaired in the transportation storage.And, generally, microtubular 40 does not provide with this utility model device, but select according to doctor's experience and individual preference, therefore, get in the bolt operation reality clinical, when the needs secondary is got the bolt operation, as applying external stress, make to get parts that bolt support 110 flatly is folded into microtubular 40 guide sheath pipe 270 just.Building block and the structure of each assembly below are described in detail in detail respectively: described getting ties system 100, for this utility model device realizes getting the main element of bolt operation, the bolt support 110 of getting of its tubulose by a self-expanding or cage structure forms, getting bolt support 110, to be designed to tubulose or cage structure be in order to be applicable to cylindrical this dissect physiology structure of blood vessel, and the expansion of this structure can make to get bolt support 110 and move to outside microtubular 40 time and collapsing while being retracted in guide sheath pipe 270 is folding more easily completes.In the present embodiment, described get bolt support 110 by shape-memory material particularly nitinol via being cut into, in clinical trial and empirical data in the past, can learn, nitinol meets biocompatibility requirement.In order to fold and to launch, get bolt support 110 and be designed to cut into a plurality of unit grid 113, between these grids, with superfine muscle 112, be connected with each other, and another effect of these grids 113 is, can better capture thrombosis, make it to be adsorbed on muscle 112 and remove more up hill and dale thrombosis.Described conveying and free system 200 by carrying hypotube 210, development turn 220, developing ring 230, free traction fiber 240, releasing tube 250, heat-shrink tube 260 and guide sheath pipe 270 form, and main body is elongated flexible member, so that the tract by microtubular 40 extend into human vas particularly in intracranial vessel by this utility model device, will get bolt support 110 and deliver to the thromboembolism place; In the present embodiment, described conveying hypotube 210 is made for the stainless steel metal pipe of elongated hollow, or as alternative, for any other elongated, flexible metal thin tube be applicable to, carrying hypotube 210 is critical pieces of sending, its far-end is connected with developing ring 230, and near-end is that hand push send part, in the time of need to freeing, in the hole 331 of the part 244 insertion rotational lock valves 330 of near-end, is locked; Development turn 220 is formed via coiling as platinumiridio or platinum-tungsten alloys by the material of Transmission X ray not, and it is fixed in the draw-in groove 216 of carrying two boss 213 of hypotube 210 far-end to be divided into, as near-end under the DSA imaging, develops and uses; The described traction fiber 240 of freeing is a pliable and tough elongated stainless steel silk, and it does advance and retreat motion relatively longitudinally in the inner cavity of pipe 211 of carrying hypotube 210; Described developing ring 230 and releasing tube 250 are round tube shape, in the present embodiment, by the material of Transmission X ray not, as platinumiridio or platinum-tungsten alloys, make; Described heat-shrink tube 260 is elongated thin-wall construction, and it has good insulating, and shrinkage ratio is large, the characteristics such as good springiness, and in the present embodiment, described heat-shrink tube 260 is made as PVC or PET for the high polymer material that meets biocompatibility requirement; The plastic tube that described guide sheath pipe 270 is the elongated hollow structure, in order to get bolt support 110 chamber slip within it easily, generally speaking, make by the polymeric material politef that particularly coefficient of friction is extremely low.Described handle system 300 is comprised of handle 310, push button 320 and rotational lock valve 330, and it is to separate the matching component that deactivation connects.Described handle 310, as doctor's handheld component, be the substantial cylindrical shape, its below is provided with front concave arc 313 and the rear concave arc 311 that facilitates hands to grip, its top is designed to plane so that push button 320 can move forward and backward thereon, and its side is provided with several anti-slip tanks 312; Described push button 320, be the arcuate structure of an applicable push-and-pull, which is provided with several for increasing the friction belt 321 of thrust; Described rotational lock valve 330, be the substantial cylindrical shape, by deasil rotating to oppress inner silica gel ring distortion, locks the conveying hypotube 210 of inserting its front aperture 331 inside, and the one circle is provided with several post bars 332 to increase spin friction power.In the present embodiment, handle 310 and push button 330 are by macromolecular material as injection mo(u)ldings such as ABS, PC, PE, and rotational lock valve 330 adopts the materials such as silica gel or rubber to make.With reference to the accompanying drawings 3 and accompanying drawing 4, and by reference to the accompanying drawings 13, structure and the assembly relation of getting bolt support 110 described, accompanying drawing 3 is for getting the axonometric chart of bolt support 110, the plane graph of accompanying drawing 4 after for its expansion.In the present embodiment, getting bolt support 110 is to adopt the molding of one section NiTi pipe cutting processing, then removes burr through electropolishing, then after subsequent heat treatment increases its super-elasticity, just finally makes.The cantilever 114 that its far-end has the bending of three energy elasticity and expands, each cantilever 114 top is equipped with protruding ball 115, its main body is many tubular brackets that unit grid 113 combines, be divided into and get bolt Free Region A and self-expanding zone B, when getting the bolt operation, thrombosis entirely is placed in Free Region A as far as possible.As understood by the skilled person, the doctor, when selecting this device specification, should consider the relation of thrombosis length and Free Region A length, and the numerical value of recommendation is, selected A size should at least grow 4-6mm than thrombosis, in order to keep respectively at least extension of 2-3mm in the both sides of thrombosis.Self-expanding zone B is diagonal bar 116 inclined-plane angled with pipe that surround by two symmetries, therefore because the gradient of diagonal bar 116 is milder, make to get under the external stress that bolt support 110 applies at guide sheath pipe 270 to collapse and foldingly become comparatively easy.The area of unit grid 113 should be too not large with respect to the external surface area of pipe, in order to avoid the radial support power of scattering and disappearing and getting bolt support 110; Should be too not little yet, and cause grid too close, increase the pulling force of getting bolt support 110 folding retraction guide sheath pipes 270.Its near-end is provided with transplants a cutting 111, is mainly to insert in developing ring 230 tube chambers 231, and by clamping, the mode of bonding, welding or welding is rigidly connected to together.With reference to accompanying drawing 5, the structure of development turn 220 is described.In the present embodiment, development turn 220 is one section helical spring structure, its material by Transmission X ray not forms via coiling as platinumiridio or platinum-tungsten alloys or platinoiridita tungsten alloy, its end face 221 by clamping, the mode of bonding, welding or welding or welding and welding is fixed in the draw-in groove 216 of carrying hypotube 210 rigidly, and simultaneously, free traction fiber 240 through its spiral endoporus 222, external diameter, spring wire size and the external diameter of the turn 220 that therefore develops is limited to the internal diameter of carrying hypotube 210 and the external diameter of freeing traction fiber 240.With reference to accompanying drawing 6, the structure of developing ring 230 is described, because releasing tube 250 and its structure are very similar, therefore 14 introduce in the lump by reference to the accompanying drawings.In the present embodiment, both are the thin-wall circular tube structure, by the material of Transmission X ray not, as platinumiridio or platinum-tungsten alloys or platinoiridita tungsten alloy, are made.The near-end 232 of described developing ring 230 is connected with the far-end 215 of carrying hypotube 210, and its far-end 233 is connected with the cutting 111 of getting bolt support 110.The cantilever 114 that described releasing tube 250 will be got bolt support 110 far-ends is accommodated in its pipeline 251 together with the ball 241 of freeing traction fiber 240 far-ends, forms active the connection.But in order after activity connects releasing, to be unlikely releasing tube 250 to be stranded in human vas, so its near-end is rigidly connected with one section formation freeing traction fiber 40.With reference to accompanying drawing 7, and by reference to the accompanying drawings 12, structure and the assembly relation of carrying hypotube 210 described.In the present embodiment, carry the structure that hypotube 210 is elongated hollow, made by the stainless steel metal pipe.As understood by the skilled person, carry the far-end of hypotube 210, especially enter the intracranial vessel section, must there is enough rigidity, but simultaneously again must be enough pliable and tough; Its near-end is that hand push send part, must have enough rigidity with transmitting thrust and avoid giving a discount in delivery process; Simultaneously, in order to adapt to and coordinate the interior tract of microtubular 40, therefore, for reaching above-mentioned expection purpose, carry hypotube 210 to be designed to the elongate cavity stainless steel metal pipe be tapered with certain taper 212, or far-end by levigate to adapt to the inner cavity size of microtubular 40, simultaneously, the far-end of conveying hypotube 210 is intracranial segment especially, is cut half so that it is more soft, more can comply with crooked blood vessel structure; But its distal-most end is electrolysis takes off zone 215, and its partial insertion developing ring 230 is affixed, second half is revealed between developing ring 230 and protruding hole 214 and forms the de-zone of electrolysis; Be provided with two boss 213 near protruding hole 214, and be divided into draw-in groove 216 in order to fixing development turn 220, as understood by the skilled person, but draw-in groove 216 overlaps with the near-end developing mark of microtubular 40 apart from the turn 220 that should be able to make to develop with the de-zone 215 of electrolysis under the DSA imaging, makes the doctor in charge can judge the location of this utility model device with respect to microtubular 40.With reference to accompanying drawing 8, and by reference to the accompanying drawings 12, accompanying drawing 13, structure and the assembly relation of freeing traction fiber 240 described.In the present embodiment, free traction fiber 240 for flexible elongated silk structure, made by stainless steel metal wire.Its far-end is provided with ball 241, as shown in accompanying drawing 13, it takes in active connection of the interior formation of pipeline 251 of releasing tube 250 together with the protruding ball 115 of getting bolt support 110 far-ends; Navigate within conveying hypotube 210 inner cavity of pipe 211 owing to freeing traction fiber 240, do not continue to penetrate in developing ring 230 after it passes protruding hole 214, therefore, in this zone, form the gradient raised up 243 to avoid developing ring 230; Same reason, form than gentle incline 242 at a section of traction fiber 240 of freeing of getting that bolt support 110 inner chambers move under water; The cylinder 244 that the near-end of freeing traction fiber 240 is overstriking, to add strong hardness, have one section levigate part 245 in the middle of it, so that the push button 330 on handle system 300 can embed and block, thereby pull, frees 240 described active connections of releasing of traction fiber.With reference to accompanying drawing 9, the structure of heat-shrink tube 260 is described.In the present embodiment, described heat-shrink tube 260 is elongated thin-wall construction, by the high polymer material, as PVC or PET, is made.Be characterized at high temperature shrinking, and it is large to have shrinkage ratio, soft flexible, the performances such as insulation.The proximal location of its contraction is positioned near the tapering 212 of carrying hypotube 210, will carry the levigate whole Bao Na of part of hypotube 210 reducings always, and the whole Bao Na in protruding hole 214 that the far-end of its contraction will be carried hypotube 210 wherein.On the one hand, the pyrocondensation jacket of heat-shrink tube 260 has increased the intensity of carrying hypotube 210 far-ends, on the other hand, must make the de-zone 215 of electrolysis and remainder insulation because electrolysis is de-, and therefore, heat-shrink tube 260 has also played the effect of insulation.With reference to accompanying drawing 10, the structure of guide sheath pipe 270 is described.In the present embodiment, the structure that described guide sheath pipe 270 is elongated hollow, made by the polymeric material politef that particularly coefficient of friction is extremely low.It will be got bolt support 110 and carry the part of hypotube 210 to be accommodated in its inner chamber 271.Its far-end 272 inserts in the female Luer endoporus 41 of microtubular 40, and this utility model device is sent in microtubular 40.15 to accompanying drawing 22 with reference to the accompanying drawings, and operation principle and the use procedure of this utility model device is elaborated, and in the present embodiment, Intracranial thrombus withdrawing device and microtubular is combined to use.From clinical effectiveness, the main target of using this utility model device is fast and the recovery revascularization of safety, thereby the cerebral tissue of redemption ischemia improves patient's Clinical Outcome.With reference to accompanying drawing 15, before using this utility model device to process thromboembolism, should be first by Angiography as Digital Subtraction visualization (DSA), determine position and the size of thrombosis 60, and select this utility model device of appropriate size model according to the size Selection suggestion of recommending, make the Length Ratio thrombosis 60 of getting bolt support 110 at least grow 4-6mm, in order to keep respectively at least extension of 2-3mm in the both sides of thrombosis 60, simultaneously, the diameter of getting bolt support 110 should be than the large 1-2mm of the internal diameter of current-carrying blood vessel 70, can be as far as possible by whole bag Na Qinei of thrombosis 60 so that get bolt support 110.With reference to accompanying drawing 16 to accompanying drawing 18, in order to illustrate that this utility model device is by rotation haemostatic valve 50(Rotating Hemostatic Valve, RHV) enter in microtubular 40 and be delivered to the process of thromboembolism thrombosis 60 positions.As understood by the skilled person, at first put the sheath technology with the Seldinger femoral artery puncture that neural intervention often adopts at present, a suitable guiding catheter is placed on to internal carotid artery or place, vertebrarterial cervical vertebra 1-2 plane, a rotation haemostatic valve is connected on the guiding catheter joint, then connect a flexible pipe, for continuous flushing.Then, select an applicable microtubular 40, and with reference to shown in accompanying drawing 16, by another rotation only the joint 51 of valve 50 be connected on the female Luer 41 of microtubular 40, and by hose connection to continuous flushing system.At this, for reducing the occurrence risk of new thrombosis, should maintain with the contact site between following each apparatus of heparin continuous flushing: a) femoral artery sheath and guiding catheter; B) microtubular and guiding catheter; C) microtubular and carry hypotube and get the bolt support, check all junction points, to determine that there is no air in the continuous flushing process enters guiding catheter or microtubular.Follow again, shown in accompanying drawing 17, by a suitable micro-wire, push microtubular 40, until the distally that the far-end developing mark 42 of microtubular 40 stretches out thrombosis 60 4mm at least.Next, with reference to accompanying drawing 16, the far-end of guide sheath pipe 270 272 is inserted in the front aperture 52 of rotation haemostatic valve 50, and advance guide sheath pipe 270 until its female Luer at microtubular 40 41 is interior firmly puts in place.To rotate haemostatic valve and tighten on guide sheath pipe 270, in case backflow of blood, but can not be too tight, in order to avoid it is impaired in the process that imports microtubular 40 to get bolt support 110.Follow again, hypotube 210 is carried in steady and continuous propelling, will get bolt support 110 and push microtubular 40, when the soft of described conveying hypotube 210 enters microtubular 40, unscrew rotation haemostatic valve 50, along carrying hypotube 210 to extract guide sheath pipe 270 out from its near-end.After completing this operation, will rotate haemostatic valve 50 and tighten on conveying hypotube 210, the visual heparin lock flush solution of examining instils normally, and rotation haemostatic valve 50 is unscrewed to the degree of to advancing, carrying hypotube 210.Under the DSA guiding, will get without resistance bolt support 110 and be delivered to desired location, the releasing tube 250 of its far-end is alignd, shown in accompanying drawing 18 with far-end developing mark 42 ends of microtubular 40.With reference to accompanying drawing 19 and accompanying drawing 20, illustrate that the bolt process of getting of this utility model device and thrombosis are removed the process that rear blood flow 80 recovers.Once determine that get bolt props up 110 and sent and put in place, it need to be launched, apply enough pressure towards the distal direction of carrying hypotube 210, guarantee to get bolt support 110 and can not be shifted, then withdraw microtubular 40 towards proximal direction carefully, until developing ring 230 is crossed the distal marker 42 of microtubular 40, now, get bolt support 110 and launch fully under self-expanding, and in thrombosis 60 is included in, shown in accompanying drawing 19.Follow again, tighten rotation haemostatic valve 50, in case carry hypotube 210 to move, and Filled Balloon is blocked the near-end blood flow momently, use syringe or the pump suction guiding catheter of 60mL simultaneously, and this utility model device and microtubular 40 are done as a wholely slowly and reposefully to withdraw, until be recovered in guiding catheter, then withdraw from guiding catheter.After bolt support 110 is got in taking-up, the bolt support 110 of getting that is stained with thrombosis is immersed in 0.9% normal saline fully, scrubs remained blood and the thrombosis removed on it.At once radiography is observed the revascularization situation, from the development situation of the branch vessel in current-carrying blood vessel 70 distally, can indirectly judge the degree that blood flow 80 recovers, and as the branch in current-carrying blood vessel 70 distally is close to fully, develops, and can judge that blood flow 80 recovery situations are good; As far-end develops poorly, can judge that thrombosis do not remove totally, can carry out secondary and get bolt.At first, normal saline flushing guide sheath pipe 270 with 0.9%, then along carrying hypotube 210 near-ends to insert in guide sheath pipe 270 inner chambers 271, and push guide sheath pipe 270 towards distal direction, to get bolt support 110 under the effect of its external pressure collapses and folds in guide sheath pipe 270, then again by described operation, carrying out secondary gets bolt, until blood flow 80 returns to degree shown in accompanying drawing 20.So just reach this utility model device and got the clinical effect of bolt as machinery.With reference to accompanying drawing 21 and accompanying drawing 22, illustrate and remove active connect and electrolysis is de-gets the bolt support by its permanent process be placed in patient body.Generally speaking, for reducing blood vessel injury, in same blood vessel, generally be no more than and get the bolt operation for 6 times, although because the radical elasticity of getting bolt support 110 is very little, damage to blood vessel wall almost can be ignored, but consider that it lacks clinical data verification, therefore, if still fail thrombosis is removed fully after getting for several times the bolt operation, most probable situation is, there is remaining thrombosis 61 to be bonded in securely on the current-carrying blood vessel wall, in this case, after can considering to remove active the connection, the far-end of getting 110 sealings of bolt support is opened, and then will get bolt support 110 and keep somewhere in the thromboembolism place after taking off fusing by electrolysis.Remove the active process connected as follows: will carry the near-end of hypotube 210 together with in the hole 331 of freeing traction fiber 240 insertion rotational lock valves 330 and until the end, clockwise rotate screw thread to oppress inner silica gel ring, make it distortion and the conveying hypotube 210 of locking insertion, free the near-end 244 that traction fiber 240 stretches out the overstriking of carrying hypotube 210 is deep in handle 310 simultaneously, push button 320 on handle embeds and blocks the levigate part 245 of freeing traction fiber 240 near-ends simultaneously, proximad pulls push button 320, make to free traction fiber 240 with respect to carrying hypotube 210 proximads to slide, thereby make the ball 241 on it cross protruding ball 115 and drive releasing tube 250 proximad slip together, when surpassing predetermined pull, make protruding ball 115 from discharging 250, and cantilever 114 will expand automatically owing to having elasticity, thereby the far-end of getting 110 sealings of bolt support is opened, and under the radial support power effect of getting bolt support 110, remaining thrombosis 61 is oppressed to current-carrying blood vessel 70 both sides, shown in accompanying drawing 21, but next the process in the de-zone 215 of the de-fusing of electrolysis electrolysis is described.Electrolysis is de-is the principle part fusing that rustless steel is exposed that utilizes Anodic to dissolve, as understood by the skilled person, when putting into a torch and being energized to 3mA in the blood of human body, can form microemboli around it, its content is comprised of erythrocyte, leukocyte, platelet and Fibrinogen, these microembolis with anion are gathered in around the rustless steel exposed part, but form micro-electric loops with the de-zone 215 of the electrolysis of conveying hypotube 210 as anode.When actual clinical manipulation, often under the effect of special-purpose electric reliever, adopt 1mA, the 3V unidirectional current, the part of anodic bonding outside the near-end human body of carrying hypotube 210, negative electrode is connected on an aseptic puncture needle that is inserted in shoulder or pars inguinalis.After connecting in this case electric reliever, but electrolysis de-regional 215 places of the function of current in carrying hypotube 210 unique exposed and blood, make its melting, fracture, like this, under without any the pulling force effect, get bolt support 110 and come off in the thromboembolism position, and blood flow 80 also is able to the inner chamber for the treatment of the preponderant disease instead of the secondary disease bolt support 110 hollows, flows through and keep unimpeded.Permanent while being placed in patient body when installing, need to carry out lifelong anticoagulant therapy to the patient.
From above discussion, can draw, get the bolt technology than existing machinery, advantage of the present utility model and good effect are: by getting the far-end sealing of bolt support, the pin device thrombosis fragment ease in the clinical manipulation process of getting of having improved existing supporting structure distad causes the thinner blood vessel of far-end and the perforating branches blood vessel drawback of thromboembolism again; Simultaneously can far-end be reopened by removing active the connection again, and be placed in patient body as the blood flow remodeling device through the de-fusing of electrolysis, avoid like this distal end barrier normal blood flow of sealing to cause again the risk of thromboembolism; And be connected in the not label of Transmission X ray that has of getting bolt support two ends, making to get bolt can operate visually under the support of digital subtraction angiography system, and makes to get bolt accurately and reliably; And do not use thrombolytic drug due to this utility model device, thereby greatly reduced the cerebral hemorrhage incidence rate caused because of thrombolytic drug in getting the bolt process; And only advance and withdraw this device and just can complete and get bolt operation, with traditional bolt operation of getting, compare, operation process has been greatly simplified, both alleviated doctor's workload, get valuable treatment time for the patient again, striven for the more time for the treatment of reversible ischemic tissue of brain, extended to a certain extent the therapeutic time window of Ischemic Stroke, thereby can make more patients be benefited.It is emphasized that; it is only below preferred embodiment of the present utility model; not this utility model is done to any pro forma restriction; any modification simply, equivalent variations and modification that every foundation technical spirit of the present utility model is done above embodiment, all still belong in the protection domain of technical solutions of the utility model.

Claims (24)

1. an Intracranial thrombus withdrawing device, comprise getting tying system, carry and free system, handle system and guide sheath pipe, it is characterized in that: described get tie that turnkey draws together the tubulose of a self-expanding or cage structure get the bolt support; Described conveying and the system of freeing comprise that the conveying hypotube of an elongated hollow and connection get the bolt support and carry the developing ring of hypotube, free traction fiber longitudinally advance and retreat slip in the inner cavity of pipe of carrying hypotube, its far-end forms activity with the far-end of getting the bolt support and is connected and will gets the sealing of bolt rack far end in releasing tube; Described handle system comprises handle and the push button that a hands grips, and the valve of a rotatable locking; Described guide sheath pipe is taken in the described part of getting bolt support and conveying and freeing system wherein.
2. a kind of Intracranial thrombus withdrawing device according to claim 1, it is characterized in that: the described bolt support of getting is made via having hyperelastic cuts in metallic pipe, can be under the external pressure applied by microtubular, flatly folding and be transferred in microtubular inside, and, when the external pressure applied by microtubular disappears, self-expanding expands into complete tubulose or cage structure.
3. a kind of Intracranial thrombus withdrawing device according to claim 2, it is characterized in that: the described bolt support of getting has near-end and far-end, and its far-end seals.
4. a kind of Intracranial thrombus withdrawing device according to claim 3 is characterized in that: the described far-end of getting its sealing of bolt support can be freed traction fiber and removes by being pulled, and the bolt rack bore of getting of tubulose or cage structure is kept clear.
5. a kind of Intracranial thrombus withdrawing device according to claim 3 is characterized in that: the described bolt rack far end of getting is provided with at least two cantilevers of can the elasticity bending and expanding, and described cantilever can bending income releasing tube, makes to get the sealing of bolt rack far end.
6. a kind of Intracranial thrombus withdrawing device according to claim 5, it is characterized in that: described cantilever is provided with protruding ball, and cantilever can be taken in together releasing tube with protruding ball and form active the connection.
7. a kind of Intracranial thrombus withdrawing device according to claim 1, it is characterized in that: the described traction fiber far-end of freeing is provided with and gets the similar ball of bolt rack far end, the described traction fiber of freeing can slide on advance and retreat ground in the inner cavity of pipe of carrying hypotube, and ball is delivered to the protruding ball distally of getting the bolt support, take in together releasing tube and form active the connection.
8. a kind of Intracranial thrombus withdrawing device according to claim 1, it is characterized in that: the described traction fiber of freeing is under the pulling of handle system push button, can in the inner cavity of pipe of carrying hypotube, slide by proximad, and make ball cross protruding ball and drive releasing tube proximad slip together, thereby protruding ball is deviate from from releasing tube, and automatically expand under the elastic reaction of cantilever, remove the far-end of getting the sealing of bolt support.
9. a kind of Intracranial thrombus withdrawing device according to claim 1 is characterized in that: the described bolt support of getting separates with carrying hypotube after electrolysis is de-.
10. a kind of Intracranial thrombus withdrawing device according to claim 1, it is characterized in that: the described far-end of getting the bolt support is connected respectively and has not label releasing tube and the developing ring of Transmission X ray with near-end.
11. a kind of Intracranial thrombus withdrawing device according to claim 10 is characterized in that: label releasing tube and the developing ring of described not Transmission X ray are made by platinumiridio or platinum-tungsten alloys.
12. a kind of Intracranial thrombus withdrawing device according to claim 1 is characterized in that: described conveying hypotube is made by the stainless steel metal pipe of elongated hollow.
13. a kind of Intracranial thrombus withdrawing device according to claim 1 is characterized in that: the described traction fiber of freeing is made by pliable and tough elongated tinsel, and its length should be able to guarantee that near-end exposes the near-end of carrying hypotube.
14. a kind of Intracranial thrombus withdrawing device according to claim 1, it is characterized in that: described guide sheath pipe is made by the polymeric material politef, its inner chamber and length dimension should be able to guarantee to get bolt support and conveying and free system accommodating, and its exocoel size should be able to guarantee to push in the female Luer endoporus of microtubular.
15. a kind of Intracranial thrombus withdrawing device according to claim 2 is characterized in that: the described bolt support of getting is made by the shape-memory material nitinol, and it forms a plurality of unit grids by interconnective muscle.
16. a kind of Intracranial thrombus withdrawing device according to claim 2 is characterized in that: described Intracranial thrombus withdrawing device is sent with the delivery device microtubular with near-end and far-end.
17. a kind of Intracranial thrombus withdrawing device according to claim 2 is characterized in that: do not expand when described Intracranial thrombus withdrawing device is contained in microtubular, expand by the microtubular moved to near-end.
18. a kind of Intracranial thrombus withdrawing device according to claim 9, it is characterized in that: but the de-zone of electrolysis formed between described conveying hypotube far-end and developing ring, can after energising, fuse and keep somewhere in the thromboembolism position after making to get the separation of bolt support, thereby making restoration of blood flow unobstructed.
19. a kind of Intracranial thrombus withdrawing device according to claim 9 is characterized in that: the described bolt support of getting adopts the de-or mechanical ways of relief of hydrolysis to separate with carrying hypotube.
20. a kind of Intracranial thrombus withdrawing device according to claim 18 is characterized in that: describedly keep somewhere getting the bolt rack surface and can be coated with anticoagulant or antiplatelet drug in the thromboembolism position.
21. a kind of Intracranial thrombus withdrawing device according to claim 7 is characterized in that: described activity is connected to while bearing over predetermined pull and lost efficacy.
22. a kind of Intracranial thrombus withdrawing device according to claim 10 is characterized in that: described developing ring by clamping, the mode of bonding, welding or welding will get the bolt support and carry linking together of hypotube rigidity.
23. a kind of Intracranial thrombus withdrawing device according to claim 22, it is characterized in that: described bolt support and the predetermined inefficacy pulling force that power should be greater than active connection that is connected of carrying the hypotube rigidity got, being rigidly connected of developing ring place can not be lost efficacy before active Joint failure.
24., according to the described a kind of Intracranial thrombus withdrawing device of claim 12 or 13, it is characterized in that: described conveying hypotube and the length of freeing traction fiber should be able to guarantee the Intracranial thrombus withdrawing device is delivered to the distally of the thrombosis of thromboembolism.
CN201320317548.XU 2013-06-04 2013-06-04 Intracranial thrombus removing device Withdrawn - After Issue CN203379185U (en)

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CN103284775A (en) * 2013-06-04 2013-09-11 加奇生物科技(上海)有限公司 Encephalic thrombosis removing device
CN105455878A (en) * 2016-01-26 2016-04-06 加奇生物科技(上海)有限公司苏州分公司 Catching device
CN105662534A (en) * 2016-01-06 2016-06-15 赵烜 Blood vessel thrombus-taking device with spine-shaped structures and thrombus therapeutic instrument thereof
CN105662532A (en) * 2016-01-06 2016-06-15 赵烜 Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same
CN105662533A (en) * 2016-01-06 2016-06-15 赵烜 Blood-vessel embolectomy device with helical structure and thrombus treating apparatus with the same
CN107080568A (en) * 2016-02-12 2017-08-22 柯惠有限合伙公司 The label of vascular arrangement is attached
CN108778389A (en) * 2016-04-14 2018-11-09 美敦力瓦斯科尔勒公司 The guiding for entering port with spiral shape extends conduit
CN109044483A (en) * 2018-07-26 2018-12-21 河南亚都实业有限公司 A kind of conduit for removal of thromboses
CN109259827A (en) * 2018-09-05 2019-01-25 北京爱琳医疗科技有限公司 The processing method of external member of performing the operation and puncture needle external member, puncture needle external member
CN109464175A (en) * 2018-12-21 2019-03-15 北京久事神康医疗科技有限公司 Thrombus withdrawing device and its application method
CN111380782A (en) * 2019-05-25 2020-07-07 郑州普湾医疗技术有限公司 Sensor alloy suspension wire and thrombelastogram instrument with same
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CN103284775B (en) * 2013-06-04 2015-06-10 加奇生物科技(上海)有限公司 Encephalic thrombosis removing device
CN103284775A (en) * 2013-06-04 2013-09-11 加奇生物科技(上海)有限公司 Encephalic thrombosis removing device
CN105662534A (en) * 2016-01-06 2016-06-15 赵烜 Blood vessel thrombus-taking device with spine-shaped structures and thrombus therapeutic instrument thereof
CN105662532A (en) * 2016-01-06 2016-06-15 赵烜 Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same
CN105662533A (en) * 2016-01-06 2016-06-15 赵烜 Blood-vessel embolectomy device with helical structure and thrombus treating apparatus with the same
CN105662533B (en) * 2016-01-06 2020-09-04 珠海通桥医疗科技有限公司 Blood vessel thrombus taking device with spiral structure and thrombus therapeutic instrument thereof
CN105455878A (en) * 2016-01-26 2016-04-06 加奇生物科技(上海)有限公司苏州分公司 Catching device
CN107080568B (en) * 2016-02-12 2020-03-03 柯惠有限合伙公司 Marker attachment for vascular devices
CN107080568A (en) * 2016-02-12 2017-08-22 柯惠有限合伙公司 The label of vascular arrangement is attached
CN108778389A (en) * 2016-04-14 2018-11-09 美敦力瓦斯科尔勒公司 The guiding for entering port with spiral shape extends conduit
CN109044483A (en) * 2018-07-26 2018-12-21 河南亚都实业有限公司 A kind of conduit for removal of thromboses
CN109259827A (en) * 2018-09-05 2019-01-25 北京爱琳医疗科技有限公司 The processing method of external member of performing the operation and puncture needle external member, puncture needle external member
CN109464175A (en) * 2018-12-21 2019-03-15 北京久事神康医疗科技有限公司 Thrombus withdrawing device and its application method
CN109464175B (en) * 2018-12-21 2023-10-20 北京久事神康医疗科技有限公司 Thrombus removal device and method of using same
CN111380782A (en) * 2019-05-25 2020-07-07 郑州普湾医疗技术有限公司 Sensor alloy suspension wire and thrombelastogram instrument with same
CN113827309A (en) * 2020-06-08 2021-12-24 微创神通医疗科技(上海)有限公司 Medical instrument traction device, operating handle and bracket system
CN113827309B (en) * 2020-06-08 2023-12-22 微创神通医疗科技(上海)有限公司 Medical instrument traction device, operating handle and bracket system
WO2023024257A1 (en) * 2021-08-24 2023-03-02 北京泰杰伟业科技有限公司 Adjustable thrombectomy apparatus

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