CN111345869B

CN111345869B - Thrombus taking device

Info

Publication number: CN111345869B
Application number: CN201811578155.8A
Authority: CN
Inventors: 单烁; 李思漪; 胡龙虎
Original assignee: Lifetech Scientific Shenzhen Co Ltd
Current assignee: Lifetech Scientific Shenzhen Co Ltd
Priority date: 2018-12-20
Filing date: 2018-12-20
Publication date: 2021-07-30
Anticipated expiration: 2038-12-20
Also published as: CN111345869A

Abstract

The invention relates to a thrombus taking device which comprises a thrombus taking device, and further comprises a first guide wire and a second guide wire, wherein the thrombus taking device comprises a first thrombus taking part, the first thrombus taking part comprises a first net rod unit and a second net rod unit, the first net rod unit and the second net rod unit are spirally wound around a central shaft of the first thrombus taking part in the length direction along the clockwise direction or the anticlockwise direction, a thrombus inlet is formed between the first net rod unit and the second net rod unit, the far end of the first guide wire is connected with the near end of the first net rod unit, the far end of the second guide wire is connected with the near end of the second net rod unit, the whole process can adopt a relatively active and manually controllable mode, the operation is simple, and the thrombus taking effect is achieved on soft thrombus and hard thrombus.

Description

Thrombus taking device

Technical Field

The invention relates to the field of medical instruments, in particular to a thrombus removal device.

Background

Stroke is a common disease type in medicine, China is also a world-wide world with stroke, and stroke has become the first cause of death of Chinese residents: relevant epidemiological studies have shown that 3 of every 4 patients with stroke present with varying degrees of disability.

Acute Ischemic Stroke (AIS), commonly known as cerebral infarction, is a nerve tissue injury caused by ischemic necrosis of local brain tissue due to sudden blockage of cerebral blood flow. Acute ischemic stroke is the most common type of stroke and is the main disease causing death and disability in the middle-aged and elderly. Especially acute cerebral apoplexy caused by great vessel occlusion, the disease condition is dangerous, and the death rate and disability rate are high. Once stroke occurs, great physical and psychological harm is caused to the patient, and heavy burden is also caused to the family and the society of the patient.

The recanalization of blood vessels is the key to the treatment of acute ischemic stroke. The current conventional methods for treating acute ischemic stroke include two main categories: interventional thrombolysis and mechanical thrombus removal.

The interventional thrombolysis is that the catheter injects the thrombolysis agent near the focus of the blood vessel where the pathological changes are located, so that high thrombolysis agent concentration is formed in the focus of the blood vessel instantly, the thrombolysis speed is accelerated, and the chance of recanalization of the blood vessel is increased. Firstly, venous thrombolysis should be performed within 3 hours of onset, and arterial thrombolysis time window is within 6 hours, and only about 5% of cerebral apoplexy patients can receive thrombolysis treatment; in addition, the time for treating the blood vessel recanalization by thrombolysis is long, and the symptomatic intracranial hemorrhage rate after thrombolysis is high. The thrombolytic therapy is only suitable for small thrombus with small volume, the effect on the small thrombus with large volume is not ideal, in the acute middle cerebral artery and cerebral infarction, if the thrombus length exceeds 8mm, the venous thrombolysis can hardly lead the blocked blood vessel again, and even if the blood vessel can be led again, the probability of secondary blockage is high.

In order to solve the problems, for patients who exceed a thrombolysis time window and have thrombolysis treatment contraindications, a mechanical device can be used for removing thrombus, so that the method can quickly recanalize the occluded blood vessel, improve the recanalization rate of the blood vessel, reduce the dose of thrombolytic drugs, reduce the incidence rate of symptomatic cerebral hemorrhage, prolong the treatment time window and shorten the recanalization time, thereby striving for more time for reversible ischemic brain tissues and obviously improving the prognosis of the patients.

The thrombus removal products available in the market all have a certain effect on soft thrombus, but have no good effect on hard thrombus. The hard thrombus has strong viscoelasticity, is difficult to compress, and the soft thrombus is fragile. It has been reported in the literature that a force required for a hard thrombus is 9mN/mm when the thrombus is compressed by 50% in the height direction²The force required for softening the thrombus is 0.7mN/mm²(1/13 for force of compression hard thrombus). All these devices are not effective in removing hard thrombi, and most of cerebral apoplexy thromboembolisms are caused by hard thrombi.

Disclosure of Invention

In view of this, it is necessary to provide an embolectomy device capable of efficiently removing a hard thrombus.

The thrombus removal device comprises a thrombus removal device, and further comprises a first guide wire and a second guide wire, wherein the thrombus removal device comprises a first thrombus removal part, the first thrombus removal part comprises a first net rod unit and a second net rod unit, the first net rod unit and the second net rod unit are spirally wound around the central axis of the first thrombus removal part in the length direction along the clockwise direction or the anticlockwise direction, a thrombus inlet is formed between the first net rod unit and the second net rod unit, the distal end of the first guide wire is connected with the proximal end of the first net rod unit, and the distal end of the second guide wire is connected with the proximal end of the second net rod unit.

Further, at least one of the first net rod unit and the second net rod unit is an elongated net structure.

Furthermore, the first guide wire is a regulating guide wire, the second guide wire is a push-pull guide wire, the first net rod unit and the second net rod unit are of long strip-shaped net structures, and the average area of meshes of the first net rod unit is smaller than that of meshes of the second net rod unit.

Further, the first net rod unit and the second net rod unit are of a single rod structure.

Further, the first guide wire is a regulating guide wire, the second guide wire is a push-pull guide wire, and the axial length of the second net rod unit is shorter than that of the first net rod unit.

Further, the embolectomy device comprises a second embolectomy portion, the first embolectomy portion and the second embolectomy portion are sequentially connected from a proximal end to a distal end, the first embolectomy portion comprises a channel, the second embolectomy portion comprises an inner cavity, the channel penetrates from the proximal end to the distal end of the first embolectomy portion, and the channel and the inner cavity are communicated with each other.

Further, the second bolt taking part comprises a plurality of net rods which are connected in a cross mode to form a net-shaped structure.

Further, the second embolectomy portion comprises a plurality of net rods, and the net rods are parallel to the central axis of the embolectomy device in the length direction.

Further, the first embolectomy portion comprises a first embolectomy portion mesh structure, the second embolectomy portion comprises a second embolectomy portion mesh structure, and the maximum mesh area of the second embolectomy portion mesh structure is smaller than the minimum mesh area of the first embolectomy portion mesh structure.

Further, the distal end of the embolectomy device is arranged in an opening shape or a closed shape.

The thrombus taking device is provided with the first net rod unit and the second net rod unit, the far end of the first guide wire is connected with the near end of the first net rod unit, the far end of the second guide wire is connected with the near end of the second net rod unit, when thrombus is captured, when the thrombus taking device cannot achieve the expected effect through self expansion, the first guide wire or the second guide wire is pushed, the first net rod unit connected with the first guide wire or the second net rod unit connected with the second guide wire is radially expanded again to fully extrude the thrombus, meanwhile, a thrombus inlet between the first net rod unit and the second net rod unit is enlarged, the thrombus is wrapped in the thrombus taking device, in addition, when the thrombus is recovered, the first guide wire and the second guide wire are withdrawn simultaneously, a thrombus inlet between the first net rod unit and the second net rod unit is reduced, the thrombus is clamped or sealed in the thrombus taking device, thrombus separation is avoided, and relatively active thrombus can be taken in the whole process, Can be manually controlled, is simple to operate, and has thrombus removing effect on soft thrombus and hard thrombus.

Drawings

Fig. 1 is a schematic view of a thrombus removal device according to a first embodiment.

Fig. 2 is a schematic view of the self-expansion of the embolectomy device provided in the first embodiment.

Fig. 3 is a schematic view of the first embodiment providing the embolectomy device expanded again.

Fig. 4 is a schematic diagram illustrating a retracted state of the embolectomy device provided in the first embodiment.

Fig. 5 is another schematic view of the self-expanding embolectomy device provided in the first embodiment.

Fig. 6 is a schematic view of the embolectomy device provided in the first embodiment after being cut in the axial direction.

FIG. 7 is a schematic distal end view of an alternative embodiment of a thrombectomy device.

FIG. 8 is a schematic view of a second embodiment of a self-expanding embolectomy device.

FIG. 9 is a schematic view of the second embodiment providing the embolectomy device re-expanded.

Fig. 10 is a schematic view of the second embodiment of the embolectomy device cut in the axial direction.

FIG. 11 is a schematic view of the second embodiment of the bolt remover in a retracted state.

FIG. 12 is a schematic view of the first embodiment providing the thrombectomy device capturing thrombi after re-expansion in the blood vessel.

Fig. 13 is a schematic view of the first embodiment providing the thrombus remover withdrawn immediately after the thrombus is captured in the blood vessel.

FIG. 14 is a schematic view of the first embodiment of the thrombectomy device after the thrombectomy device captures thrombi in the blood vessel and before the thrombectomy device enters the recovery catheter.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, but rather should be construed as broadly as the present invention is capable of modification in various respects, all without departing from the spirit and scope of the present invention.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.

First, it is emphasized that reference to "proximal" in the context of embodiments of the present invention refers to the end that is closer to the operator during operation; "distal" means the end that is distal to the operator during operation; "axial" refers to a direction parallel to the line joining the center of the distal end and the center of the proximal end of the medical device; "radial" refers to a direction perpendicular to the "axial" direction.

The first embodiment provides a thrombectomy device 100. The thrombus removal device 100 comprises a thrombus removal device 1, a first guide wire, a second guide wire and a microcatheter 4. As shown in FIG. 1, the embolectomy device 1 is compressed within a microcatheter 4. Fig. 2 shows the state of the embolectomy device 1 after being completely self-expanded, wherein the embolectomy device 1 comprises a first embolectomy portion 203 and a second embolectomy portion 204, wherein the first guide wire is a control guide wire 3, and the second guide wire is a push-pull guide wire 2.

In this embodiment, the embolectomy device 1 is a mesh tube structure. The thrombus taking device 1 has an overall length after complete expansion of 15-60 mm, preferably 15-40 mm, 35-40 mm and 25-45 mm, a maximum length in the radial direction of 2-6 mm, preferably 2-3 mm, 3-4 mm and 5-6 mm, and a thickness of a pipe or a sheet of 0.05-0.5 mm. The embolectomy device 1 may be formed by laser cutting a metal tube (e.g., a NiTi alloy tube) having shape memory effect and superelasticity, then molding the tube by a mold, and then heat-treating the tube to shape. Alternatively, the embolectomy device 1 may be formed by cutting a metal sheet having shape memory effect and superelasticity, then molding the cut metal sheet by a mold, and then performing heat treatment for shaping. Or, the embolectomy device 1 can be manufactured by weaving a metal wire with shape memory effect and superelasticity, and then performing die forming and heat treatment shaping. Alternatively, the embolectomy device 1 may be made of a highly elastic polymer material. Suitable materials mentioned above are well known to those skilled in the art and will not be described in detail here.

This first portion of getting embolus 203 includes first net pole unit 111 and second net pole unit 112, and this first net pole unit 111 and this second net pole unit 112 are independent each other, and first net pole unit 111 and second net pole unit 112 are around first portion of getting 203 length direction center pin along clockwise or anticlockwise spiral, and after catching the thrombus, the spiral design of first net pole unit 111 and second net pole unit can wrap up the thrombus better, can effectively avoid the thrombus to drop. The thrombus inlet 41 is provided between the first and second

net rod units

111 and 112.

The distal end of the regulating guide wire 3 is connected with the proximal end of the first net rod unit 111, and the distal end of the push-pull guide wire 2 is connected with the proximal end of the second net rod unit 112. The push-pull guide wire 2 and the regulating guide wire 3 are parallel or intersected with each other. Wherein, the embolectomy device 1 can be switched between a recovery position and a deployment position by pushing and pulling the push-pull guide wire 2. In the retrieval position, the embolectomy device 1 is retrieved into the microcatheter 101; in the deployed position, the embolectomy device 1 is pushed out of the microcatheter 101 for self-expanding release. The sizing guidewire 3 can radially expand the first thrombus removal portion 203 again while controlling the size of the thrombus entry port 41. In the operation process, the push-pull guide wire 2 can be used for regulation and control at the same time, and the regulation and control guide wire 3 can be used for push-pull at the same time.

In this embodiment, the first net rod unit 111 and the second net rod unit 112 are both strip-shaped net structures, and the two strip-shaped net structures are spirally wound clockwise or counterclockwise around the central axis of the first bolting part 203 in the length direction to form a similar tubular structure, and the inside of the tubular structure is provided with a channel 4, and the channel 4 extends and penetrates in the axial direction of the first bolting part 11. On the tubular structure, the opening between the first mesh rod unit 111 and the second mesh rod unit 112 is the thrombus inlet 41. The elongated mesh structure is a single-row mesh, and may be a plurality of rows of meshes in other embodiments.

Referring to fig. 3, after the thrombus taking device 1 is in a complete expansion state, the regulation guide wire 3 is pushed in a distal direction, the proximal end of the first net rod unit 111 further expands radially, so that the force of the proximal end of the first net rod unit 111 for extruding thrombus between the thrombus taking device and a blood vessel wall is increased, soft thrombus is embedded between net rods of the thrombus taking device 1, meanwhile, a thrombus inlet 41 between the first net rod unit 111 and the second net rod unit 112 is enlarged, hard thrombus and soft thrombus can enter a channel 4 of a first thrombus taking part conveniently, the regulation guide wire 3 is pushed in the distal direction, the regulation guide wire 3 drives the thrombus to move, and the effect of peeling the thrombus from the blood vessel wall is achieved; referring to fig. 4, when the control guide wire 3 and the push-pull guide wire 2 are pulled in the proximal direction, the proximal end of the first net rod unit 111 is radially compressed, and the thrombus inlet 41 between the first net rod unit 111 and the second net rod unit 112 becomes smaller, so as to prevent the thrombus from escaping from the channel 4 of the first thrombus extraction part.

In one embodiment, the average area of the cells of the first wire rod unit 111 is smaller than the average area of the cells of the second wire rod unit 112. Due to the design, the first net rod unit 111 has larger radial force and larger radial force, and the thrombus-extruding force of the thrombus-taking device is larger in the expansion and deployment process, so that thrombus can more easily enter a thrombus inlet, and the thrombus-capturing capacity is improved; the average area of the grids of the first net rod unit 111 is small, so that soft red thrombus is easily adhered to the net rods of the first net rod unit 111, and the red thrombus can be wound on the thrombus taking device by matching with the action of the second net rod unit 112, so that the red thrombus is not easy to fall off and escape. In other embodiments, the average area of the cells of the first wire bar unit 111 is equal to the average area of the cells of the second wire bar unit 112.

Referring again to fig. 2, in the present embodiment, the axial length of the first net rod unit 111 is longer than the axial length of the second net rod unit 112 when the embolectomy device 1 is in the fully expanded state. The adjusting guide wire 3 is pushed in the distal direction, so that the proximal end of the first net rod unit 111 is aligned with the proximal end of the second net rod unit 112 in the radial direction, and at this time, the axial length of the effective embolectomy of the first embolectomy portion 203 is the longest, and the axial length of the effective embolectomy is the same as the axial length of the second net rod unit 112. It should be noted here that the bolting section having an axial length effective for bolting needs to include both a part of the first net rod unit 111 and a part of the second net rod unit 112. In other embodiments, the axial length of the second wire rod unit 112 may be shorter than or equal to the axial length of the first wire rod unit 111.

Referring to fig. 5, fig. 5 is another view of the embolectomy device 1 in a fully expanded state, wherein the first embolectomy portion 203 and the second embolectomy portion 204 are sequentially connected from the proximal end to the distal end, the second embolectomy portion 204 comprises a lumen 5, and the channel 4 of the first embolectomy portion 203 and the lumen 5 of the second embolectomy portion 204 are communicated with each other.

Referring to fig. 6, the second plug-taking portion 204 includes a plurality of net rods, the net rods are connected in a cross manner to form a plurality of meshes 2040, and the meshes are spliced to form a net structure. The first embolectomy portion 203 includes a first embolectomy portion mesh structure including a mesh (e.g., 1110) of the first wire rod unit 111 and a mesh (e.g., 1120) of the second wire rod unit 112. The maximum mesh area of the mesh structure of the second embolectomy part 204 is smaller than the minimum mesh area of the first embolectomy part 203, so that the thrombus entering the lumen 5 of the second embolectomy part 204 is prevented from escaping from the mesh of the mesh structure of the second embolectomy part 204. In fig. 6, the thrombus inlet 41 between the first net rod unit 111 and the second net rod unit 112 can be seen, the thrombus inlet 41 has a spiral shape around the central axis of the first embolectomy portion 203 in the longitudinal direction, and in other embodiments, the number of the thrombus inlets 41 is plural, and the shape is not limited. It is understood that the mesh of the mesh structure of the second embolectomy portion 204 and the mesh of the mesh structure of the first embolectomy portion 203 are both entrance ports for thrombus.

In other embodiments, the second embolectomy device comprises a plurality of mesh rods parallel to the lengthwise central axis of the embolectomy device. In other embodiments, the mesh rods are parallel to each other and may not be parallel to the longitudinal central axis of the embolectomy device.

Referring again to fig. 5, the distal end of the embolectomy device 1 is provided with an opening, which facilitates the distal end of the embolectomy device 1 to be attached to the vessel wall, and prevents thrombus located between the embolectomy device and the vessel wall from escaping out of the distal end of the embolectomy device 1. In other embodiments, in fig. 7, the distal end of the embolectomy device 1 is arranged in a closed shape, and the distal net rod 2041 of the embolectomy device 1 is extended and converged at the distal end 2043. The design enables the far end of the embolectomy device 1 to form a net-shaped closed state, thrombus can stay in the far end of the embolectomy device 1 in a larger possible way, the possibility that the thrombus caught in the far end of the embolectomy device 1 escapes and is lost in the withdrawing process is reduced, and the stability and the reliability of the trapped thrombus are improved.

The second embodiment provides a thrombectomy device 200. In contrast to the first embodiment, referring to fig. 8, the first and second

wire rod units

111 and 112 are each of a single rod structure. The two single-rod structures are twisted clockwise or counterclockwise around the longitudinal center axis of the first plug part 203 to form a double-spiral structure having a passage 4 inside, the passage 4 extending in the axial direction of the first plug part 203 and penetrating therethrough. The single-rod structure is made of a metal with memory and is reduced to a spiral shape through self-expansion after being released from the microcatheter.

In fig. 9, when the first net rod unit 111 and the second net rod unit 112 are expanded to be in close contact with the blood vessel wall, the control guide wire 3 is continuously pushed, and due to the spiral structure design, the first net rod unit 111 moves in the distal direction in close contact with the blood vessel wall, so that thrombus on the blood vessel wall can be detached. As shown in the expanded view of the embolectomy device in fig. 10, after the embolectomy device is expanded, the thrombus inlet 41 between the first net rod unit 111 and the second net rod unit 112 is large, so that enough space can be provided for the thrombus to enter the embolectomy device, and the thrombus can be captured. Referring to fig. 9 again, after the thrombus extractor is released, the single-rod structure is contacted with thrombus, the second net rod unit 112 controlled by the push-pull guide wire 2 is stable and stationary, and the first net rod unit 111 controlled by the regulating guide wire 3 moves to a certain extent, so that the thrombus can be wound with the spiral rod of the first net rod unit 111, and the probability of falling of the thrombus is reduced. As shown in FIG. 11, the thrombus inlet 41 between the first net rod unit 111 and the second net rod unit 112 can be reduced by pulling the control guide wire 3, and the effect of clamping or cutting thrombus can be achieved.

In other embodiments, the first net rod unit 111 has an elongated net-shaped structure and the second net rod unit 112 has a single rod structure, or the first net rod unit 111 has a single rod structure and the second net rod unit 112 has an elongated net-shaped structure.

The embolectomy procedure with the embolectomy device 100 is as follows:

step S101: the microcatheter is advanced under X-ray to the embolization site and through the thrombus, and then along the path of the microcatheter, the microcatheter is delivered to the embolization site with the distal end of the microcatheter passing completely through the embolization site and verified by injection of a contrast agent. The micro-guide wire is withdrawn and the thrombectomy device is delivered from the proximal end of the micro-catheter. Pushing the thrombus taking device to the far end of the micro catheter through the lumen of the micro catheter, wherein the far end of the thrombus taking device does not exceed the position of the far-end pipe orifice of the micro catheter. The position of the thrombus taking device is adjusted by adjusting the position of the microcatheter, and the distal end of the thrombus taking device is arranged at the distal end of the thrombus position.

Step S102: withdraw microcatheter and release and get a bolt ware 1, treat to get the back that bolt ware 1 distal end is unfolded completely, refer to fig. 12, to distal end direction propelling movement regulation and control seal wire 3, the distance of propelling movement is 5 ~ 10mm, make first net pole unit 111 radial expansion once more, thrombus entry 41 between first net pole unit 111 and the second net pole unit 112 is expanded greatly, thrombus 5 receives the radial force that first net pole unit 111 inflation produced, receive the constraint of vascular wall 201 simultaneously, force thrombus 5 to pass through thrombus entry 41 and get into in the passageway 4. After waiting for 5min, the thrombus 5 is completely inserted into the channel 4.

Step S103: after thrombus 5 imbeds first portion 203 of emboliaing, refer to fig. 13, during the withdrawal, earlier 3 ~ 5mm of regulation and control seal wire 3 withdrawal, make first net pole unit 111 and second net pole unit 112 centre gripping thrombus 5, then withdraw push-and-pull seal wire 2 and regulation and control seal wire 3 simultaneously, thrombus 5 receives vascular wall 201 to the intraductal package power of blood, also receive the clamping and squeezing power of the net pole of first portion 203 of emboliaing simultaneously, the thrombus dehydration, the volume diminishes, viscoelasticity is strong, coefficient of friction is big, make thrombus 5 hug closely in the intracavity of getting emboliaing ware 1. When the thrombus 5 and the embolectomy device 1 move relatively during the proximal movement of the embolectomy device 1, the

small thrombus

51 and 52 in the thrombus 5 enters the lumen of the second embolectomy part 204, and the maximum mesh area of the mesh structure of the second embolectomy part 204 is smaller than the minimum mesh area of the mesh structure of the first embolectomy part 203, so that the

small thrombus

51 and 52 is attached to the lumen of the second embolectomy part 204 as shown in fig. 14, and the

small thrombus

51 and 52 is not easy to separate from the second embolectomy part 204.

Step S104: and continuously withdrawing the push-pull guide wire 2 and the regulating guide wire 3 at the same time, recovering the thrombus extractor 1 attached with the thrombus into the recovery catheter 6, and withdrawing the recovery catheter 6 carrying the thrombus out of the body to take out the thrombus.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. The thrombus removal device comprises a thrombus removal device and is characterized by further comprising a first guide wire and a second guide wire, wherein the thrombus removal device comprises a first thrombus removal part, the first thrombus removal part comprises a first net rod unit and a second net rod unit, the first net rod unit and the second net rod unit are spirally wound around a central shaft of the first thrombus removal part in the length direction in a clockwise or anticlockwise direction, a thrombus inlet is formed between the first net rod unit and the second net rod unit, the distal end of the first guide wire is connected with the proximal end of the first net rod unit, and the distal end of the second guide wire is connected with the proximal end of the second net rod unit; the first guide wire is a regulating guide wire and is used for radially expanding the first embolectomy part again; the second guide wire is a push-pull guide wire and is used for enabling the embolectomy device to be switched between a recovery position and a deployment position.

2. The embolectomy device of claim 1, wherein at least one of the first mesh rod unit and the second mesh rod unit is an elongated mesh structure.

3. The embolectomy device of claim 2, wherein the first and second wire rod units are elongated mesh structures, and the average area of the meshes of the first wire rod unit is smaller than the average area of the meshes of the second wire rod unit.

4. The embolectomy device of claim 1, wherein the first mesh rod unit and the second mesh rod unit are of a single rod construction.

5. The embolectomy device of claim 1 wherein the axial length of the second mesh rod unit is shorter than the axial length of the first mesh rod unit.

6. The embolectomy device of claim 1, wherein the embolectomy device comprises a second embolectomy portion, the first embolectomy portion and the second embolectomy portion are sequentially connected from a proximal end to a distal end, the first embolectomy portion comprises a channel, the second embolectomy portion comprises a lumen, the channel extends from the proximal end to the distal end of the first embolectomy portion, and the channel and the lumen are in communication with each other.

7. The embolectomy device of claim 6, wherein the second embolectomy device comprises a plurality of mesh rods that are cross-linked to form a mesh structure.

8. The embolectomy device of claim 6, wherein the second embolectomy device comprises a plurality of mesh rods that are parallel to a lengthwise central axis of the embolectomy device.

9. The embolectomy device of claim 6, wherein the first embolectomy device comprises a first embolectomy portion network structure and the second embolectomy portion comprises a second embolectomy portion network structure, wherein the maximum mesh area of the second embolectomy portion network structure is less than the minimum mesh area of the first embolectomy portion network structure.

10. The embolectomy device of claim 1, wherein the distal end of the embolectomy device is configured to be open or closed.