CN217717503U - Tissue transparence degree evaluation device - Google Patents
Tissue transparence degree evaluation device Download PDFInfo
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- CN217717503U CN217717503U CN202221466213.XU CN202221466213U CN217717503U CN 217717503 U CN217717503 U CN 217717503U CN 202221466213 U CN202221466213 U CN 202221466213U CN 217717503 U CN217717503 U CN 217717503U
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Abstract
The utility model discloses a tissue transparentization degree evaluation device, including the test board, the top fixed mounting of test board has aassessment board and color comparison board, the surface of color comparison board is seted up flutedly, the surface of color comparison board just is located the groove and is provided with transparent degree evaluation mechanism, including bracing piece and limiting plate in the transparent degree evaluation mechanism, and bracing piece fixed mounting is at the top of color comparison board, the utility model relates to a tissue transparentization technical field. This tissue transparentization degree evaluation device through being provided with transparency degree evaluation mechanism, places the tissue product on the aassessment board, then through rotating the colorimetric card, observes the transparency of product on with the aassessment board through the transparency of observation groove and compares for the gridlines exposure degree of both sides is unanimous, can effectually carry out quantitative evaluation to the tissue with this, especially is the middle degree transparent tissue that the flesh eye is difficult to distinguish, thereby convenient in follow-up research operation to the tissue.
Description
Technical Field
The utility model relates to a tissue transparentization technical field specifically is a tissue transparentization degree evaluation device.
Background
The tissue transparentizing technology is a technology which treats a large tissue or a complete organ by using a physical or chemical method through modes of soaking, electrophoresis or perfusion and the like, balances the refractive index of each component in a sample, is matched with tissue decoloration, changes the optical characteristics of heterogeneous components to be consistent or nearly consistent, then uses a high-refractive-index medium to match the refractive index of the tissue, reduces light scattering and the absorption of the tissue to light and enables the tissue to be optically transparent. The technology can be matched with methods such as fluorescent labeling and the like to carry out definite qualitative, positioning, quantitative analysis and the like on proteins, nucleic acids, subcellular structures and the like in tissues or organs. The tissue transparentization technology can realize high-resolution 3D structural imaging of various tissues, is helpful for revealing the structural and functional relevance in organisms, and has important scientific value and clinical diagnosis value. The most key step of the technology is that after tissue is subjected to transparentization treatment, the quantitative judgment of the transparency degree is difficult, and sometimes even after optical imaging is carried out, whether a transparent sample meets the current research requirement can be determined; at present, no scheme and standard for objectively evaluating the transparentization degree exists, and judgment is completely carried out by naked eyes, so that large errors are inevitable.
The degree of current transparentization is transparent percentage promptly and is difficult to grasp, can differentiate complete transparent tissue or complete opaque tissue, nevertheless to the unable effective aassessment of middle degree to at the in-process that carries out the aassessment, often can be because the colour comparison card is not superimposed neat, cause the aassessment data to have great deviation problem, for this reason, the utility model provides a tissue transparentization degree evaluation device.
SUMMERY OF THE UTILITY MODEL
Not enough to prior art, the utility model provides a tissue transparence degree evaluation device has solved current transparent percentage and has been difficult to hold to and the colour chip is not stacked neatly, causes the great deviation problem of aassessment data existence.
In order to achieve the above purpose, the utility model discloses a following technical scheme realizes: the utility model provides a tissue transparence degree evaluation device, includes the test board, the top fixed mounting of test board has aassessment board and color comparison board, the surface of color comparison board is seted up flutedly, the surface of color comparison board just is located the groove and is provided with transparency degree evaluation mechanism, including bracing piece and limiting plate in the transparency degree evaluation mechanism, and bracing piece fixed mounting is at the top of color comparison board, the fixed surface of bracing piece and limiting plate is connected, the surface of bracing piece just is located the internal rotation of limiting plate and is connected with the color comparison card, and the color comparison card from last to down according to having printed on respectively transparency instruction percentage "95%" to "0%" according to the principle that progressively diminishes 5% in proper order, the surface of limiting plate is provided with spacing subassembly, the observation groove has been seted up at the top of limiting plate, the extension groove has been seted up on the right side of limiting plate, the black gridline that violently indulges evenly distributed is all drawn at the top of aassessment board and color comparison board.
Preferably, including the pulling rod in the spacing subassembly, the top fixedly connected with pulling plate of pulling rod.
Preferably, the bottom fixedly connected with of pulling plate presses the clamp plate, the surface of pulling rod and the surface of limiting plate run through the slip.
Preferably, the bottom of the pressing plate is in contact with the top of the colorimetric card, and the surface of the pulling rod is sleeved with a return spring.
Preferably, two ends of the return spring are fixedly connected with one side of the pull plate opposite to the limiting plate respectively.
Preferably, the transparent gradients of the color comparison cards are all 5%, and 20 color comparison cards are arranged.
Advantageous effects
The utility model provides a tissue transparence degree evaluation device. Compared with the prior art, the method has the following beneficial effects:
(1) This tissue transparence degree evaluation device through being provided with transparency degree evaluation mechanism, places the tissue product on the aassessment board, then through rotating the colorimetric card, observes and appraises the transparency of product on the board through the transparency of observation groove for the gridlines exposure degree of both sides is unanimous, can effectually carry out quantitative aassessment to the tissue with this, especially the middle degree transparent tissue that the flesh eye is difficult to distinguish, thereby convenient in follow-up research operation to the tissue.
(2) This organize transparence degree evaluation device through being provided with spacing subassembly, utilizes reset spring's restorer for the press platen constantly subtracts progressively along with the colour comparison card, realizes compressing tightly the operation of alignment to remaining colour comparison card, with this clearance between not only can reducing the colour comparison card, makes the colour comparison card can keep neat moreover, accuracy when carrying out the contrast with the improvement transparency.
Drawings
FIG. 1 is a perspective view of the present invention;
FIG. 2 is an exploded view of the external three-dimensional structure of the present invention;
fig. 3 is an enlarged view of a partial structure at a position a in fig. 2 according to the present invention;
fig. 4 is a three-dimensional structure splitting view of the limiting component of the present invention.
In the figure: the device comprises a test board 1, a test board 2, an evaluation board 3, a colorimetric board 4, a groove 5, a transparency degree evaluation mechanism 51, a support rod 52, a limiting plate 52, a colorimetric card 53, a limiting component 54, a pulling rod 54-1, a pulling plate 54-2, a pressing plate 54-3, a return spring 54-4, an observation groove 55 and an extension groove 56.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.
Referring to fig. 1-4, the present invention provides a technical solution: a tissue transparentization degree evaluating device comprises a test board 1, the test board 1 is a workbench capable of performing test operation, an evaluation board 2 and a color comparison board 3 are fixedly installed at the top of the test board 1, tissue products are placed on the evaluation board 2, the evaluation board 2 can be detached, cleaned or replaced, a groove 4 is formed in the surface of the color comparison board 3, the groove 4 is used for facilitating the placement of a color comparison card 53 after rotation, a transparence degree evaluating mechanism 5 is arranged on the surface of the color comparison board 3 and positioned at the groove 4, the transparence degree evaluating mechanism 5 comprises a supporting rod 51 and a limiting plate 52, the limiting plate 52 is used for keeping the left side of the color comparison card 53 in order, the supporting rod 51 is fixedly installed at the top of the color comparison board 3, and the supporting rod 51 is fixedly connected with the surface of the limiting plate 52, the surface of the supporting rod 51 and the inside of the limiting plate 52 are rotatably connected with a colorimetric card 53, the transparent gradients of the colorimetric cards 53 are all 5%, the colorimetric cards 53 are provided with 20 colorimetric cards 53, the colorimetric cards 53 are respectively printed with the percentage of transparency indication from 95% to 0% according to the principle that the percentage of transparency indication sequentially decreases by 5% from top to bottom, the surface of the limiting plate 52 is provided with a limiting component 54, the limiting component 54 comprises a pulling rod 54-1, the top of the pulling rod 54-1 is fixedly connected with a pulling plate 54-2, the bottom of the pulling plate 54-2 is fixedly connected with a pressing plate 54-3, the pressing plate 54-3 is always in contact with the colorimetric card 53, the pressing plate 54-3 is also provided with an observation groove 55, the surface of the pulling rod 54-1 and the surface of the limiting plate 52 slide through, the bottom of the pressing plate 54-3 is in contact with the top of the colorimetric card 53, the surface of the pulling rod 54-1 is sleeved with a return spring 54-4, the two ends of the reset spring 54-4 are fixedly connected with one side of the pull plate 54-2 and the opposite side of the limit plate 52 respectively, the reset component 54 is arranged, the reset property of the reset spring 54-4 is utilized, the press plate 54-3 is continuously reduced along with the colorimetric card 53, the operation of pressing and aligning the remaining colorimetric cards 53 is realized, so that the gap between the colorimetric cards 53 can be reduced, and the colorimetric cards 53 can be kept in order, so as to improve the accuracy of comparison of the transparency, the top of the limit plate 52 is provided with the observation groove 55, the observation groove 55 is convenient for a person to observe the transparency, the right side of the limit plate 52 is provided with the extension groove 56, the colorimetric card 53 is convenient to rotate outwards to perform the reduction operation, the top of the evaluation plate 2 and the top of the colorimetric plate 3 are both drawn with black grid lines which are uniformly distributed in the horizontal and longitudinal directions, the tissue product is placed on the evaluation plate 2 by arranging the transparency evaluation mechanism 5, then the colorimetric card 53 is rotated, the observation of the observation groove 55 is compared with the transparency of the product on the evaluation plate 2, so that the grid lines on the two sides are consistent, the tissue contents can be effectively exposed, and the tissue content of the tissue is difficult to be effectively distinguished and easily, thereby the subsequent tissue research in the detailed technical book by the people who do not describing the technology in the field.
In operation, firstly, the tissue to be evaluated is placed on the evaluation board 2, then the colorimetric card 53 is rotated clockwise for 1 sheet at a time until the black grid lines exposed by the sequentially decreasing transparency are consistent with the exposed black grid lines observed on the tissue, so that the transparency of the tissue can be obtained, the tissue product is placed on the evaluation board 2 by the transparency evaluation mechanism 5, then the colorimetric card 53 is rotated, the transparency of the product on the evaluation board 2 is observed and compared with the transparency of the product on the evaluation board 2 by the transparency of the observation groove 55, so that the exposure of the grid lines on two sides is consistent, thereby effectively carrying out quantitative evaluation on the tissue, particularly the middle-degree transparent tissue which is difficult to distinguish by meat eyes, thereby facilitating subsequent research operation on the tissue, meanwhile, in the continuous colorimetric card 53 decreasing transparency, the restoring force of the reset spring 54-4 can make the pull plate 54-2 move, and drive the pull rod 54-1 and the contrast plate 54-3 to move vertically in the vertical direction, and the color card 53 is pressed, and the contrast card 53 can be pressed by the reset spring 54-4, so that the contrast card 53 can be pressed accurately and the contrast card 53 can be pressed by the reset spring 54-4, thereby the contrast card can be pressed and the contrast card 53 can be accurately kept aligned.
It should be noted that, in this document, relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The utility model provides a tissue transparentization degree evaluation device, includes test board (1), the top fixed mounting of test board (1) has aassessment board (2) and color comparison board (3), its characterized in that: a groove (4) is formed in the surface of the colorimetric plate (3), and a transparency degree evaluation mechanism (5) is arranged on the surface of the colorimetric plate (3) and positioned in the groove (4);
including bracing piece (51) and limiting plate (52) in transparency degree evaluation mechanism (5), and bracing piece (51) fixed mounting is at the top of colorimetric plate (3), the fixed surface of bracing piece (51) and limiting plate (52) is connected, the inside rotation that the surface of bracing piece (51) just is located limiting plate (52) is connected with colorimetric card (53), and colorimetric card (53) from last to down according to descending 5% principle in proper order printed transparency instruction percentage "95%" to "0%" respectively, the surface of limiting plate (52) is provided with spacing subassembly (54), observation groove (55) have been seted up at the top of limiting plate (52), extension groove (56) have been seted up on the right side of limiting plate (52), the black gridlines that have violently indulging evenly distributed have all been drawn at the top of aassessment board (2) and colorimetric plate (3).
2. The apparatus for evaluating the degree of tissue transparency according to claim 1, wherein: the limiting assembly (54) comprises a pulling rod (54-1), and the top of the pulling rod (54-1) is fixedly connected with a pulling plate (54-2).
3. The apparatus for evaluating the degree of tissue transparency according to claim 2, wherein: the bottom of the pulling plate (54-2) is fixedly connected with a pressing plate (54-3), and the surface of the pulling rod (54-1) and the surface of the limiting plate (52) slide in a penetrating mode.
4. The apparatus for evaluating the degree of tissue transparency according to claim 3, wherein: the bottom of the pressing plate (54-3) is in contact with the top of the color chart (53), and the surface of the pulling rod (54-1) is sleeved with a return spring (54-4).
5. The apparatus for evaluating the degree of tissue transparency according to claim 4, wherein: and two ends of the return spring (54-4) are respectively and fixedly connected with one side of the pull plate (54-2) opposite to the limiting plate (52).
6. The apparatus for evaluating the degree of tissue transparency according to claim 1, wherein: the transparent gradient of the color comparison card (53) is 5%, and 20 sheets of the color comparison card (53) are arranged.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221466213.XU CN217717503U (en) | 2022-06-13 | 2022-06-13 | Tissue transparence degree evaluation device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221466213.XU CN217717503U (en) | 2022-06-13 | 2022-06-13 | Tissue transparence degree evaluation device |
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| CN217717503U true CN217717503U (en) | 2022-11-01 |
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| CN202221466213.XU Active CN217717503U (en) | 2022-06-13 | 2022-06-13 | Tissue transparence degree evaluation device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115575341A (en) * | 2022-12-07 | 2023-01-06 | 之江实验室 | Self-healing material characterization method based on transmission spectrum change |
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2022
- 2022-06-13 CN CN202221466213.XU patent/CN217717503U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115575341A (en) * | 2022-12-07 | 2023-01-06 | 之江实验室 | Self-healing material characterization method based on transmission spectrum change |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20231114 Address after: Rooms 201 and 202, No. 17, Lane 158, Yanzhan Road, Jiuting Town, Songjiang District, Shanghai, 2016 Patentee after: Fuhai bioscience instrument (Shanghai) Co.,Ltd. Address before: 100191 No.3 Hospital of Peking University, 49 Garden Road North, Beijing, Haidian District Patentee before: PEKING University THIRD HOSPITAL (PEKING UNIVERSITY THIRD CLINICAL MEDICAL College) |
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| TR01 | Transfer of patent right |