CN212871931U - Tissue sample detection device and tissue sample rapid detection system - Google Patents
Tissue sample detection device and tissue sample rapid detection system Download PDFInfo
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- CN212871931U CN212871931U CN202022169960.4U CN202022169960U CN212871931U CN 212871931 U CN212871931 U CN 212871931U CN 202022169960 U CN202022169960 U CN 202022169960U CN 212871931 U CN212871931 U CN 212871931U
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Abstract
The utility model provides a tissue sample detection device and tissue sample rapid detection system. This tissue sample detection device contains fixing device and detecting element, fixing device is by the mark area, clamping area and fixed area are constituteed, the fixed area is located between mark area and the clamping area, one side that the mark area is close to the fixed area all is provided with the slot with one side that the clamping area is close to the fixed area, the fixed area comprises first support and second support, first support and second support all are provided with the cavity that holds detecting element, first support, the second support, the rectangle that mark area and clamping area enclose is the sample detection zone, detecting element is for detecting the slide. The utility model can detect the front and back surfaces of the tissue sample; compared with the traditional tissue slice technology, the utility model discloses the spatial structure and the spatial distribution information that remain histiocyte of bigger degree have improved the accuracy that detects, have shortened check-out time.
Description
Technical Field
The utility model relates to a pathological diagnosis field, in particular to tissue sample detection device and tissue sample rapid detection system.
Background
The traditional hematoxylin-eosin staining (HE staining) is the most basic staining method essential for the disciplines of biology, histology, pathology and cytology. Hematoxylin-eosin staining is mainly used for displaying normal components and general morphological structures of pathological changes of various tissues for observation. The method is widely applied to pathological diagnosis, teaching and scientific research and has important value.
The quality of HE staining directly affects the accuracy of pathological diagnosis. In long-term practical applications, it has been found that the following disadvantages exist in conventional HE staining: the slide glass and the cover glass adopted by the traditional HE method can only carry out single-side observation on tissue slices, cannot carry out double-side detection, and is not suitable for carrying out three-dimensional detection on the whole tissue structure. In addition, if only place the slide on observing after with current coverslip centre gripping tissue, the coverslip slides on the slide because of the adsorption affinity is less easily in the testing process, causes the landing to pollute the risk and influences detection effect.
Therefore, a rapid tissue sample detection system which can realize double-sided or three-dimensional observation, is simple and convenient to operate and is suitable for tissue blocks with the thickness of 3-500 μm is urgently needed to help doctors to make accurate judgment so as to guide clinical effective treatment.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides a tissue sample detection device and tissue sample rapid detection system. The utility model can realize double-sided or three-dimensional observation, is simple and convenient to operate, and is suitable for tissue blocks with the thickness of 3-500 mu m.
In order to realize the purpose of the utility model, the utility model provides a following technical scheme:
the utility model also provides a tissue sample detection device, this tissue sample detection device contain fixing device and detecting element.
The fixing device is composed of a mark area, a clamping area and a fixing area, the fixing area is located between the mark area and the clamping area, slots are formed in one side, close to the fixing area, of the mark area and one side, close to the fixing area, of the clamping area, the fixing area is composed of a first support and a second support, cavities for containing detection units are formed in the first support and the second support, a rectangle formed by the first support, the second support, the mark area and the clamping area in a surrounding mode is a sample detection area, and the detection units are detection slides.
Through setting up the sample detection zone at tissue sample detection device, can carry out two-sided detection just anti to the tissue sample that does not handle through the section to the realization detects comprehensively the overall state of tissue.
Preferably, the test slide comprises an upper slide and a lower slide, the tissue sample is placed between the upper slide and the lower slide, and the test slide with the tissue sample is placed in the cavities of the first bracket and the second bracket.
Preferably, the marking zone, the holding zone and the fixing zone are of an integrally formed structure.
Preferably, the first support or the second support of the fixing area is composed of a left support and a right support, and the left support or the right support is detachably connected.
Preferably, the first bracket is of a hollow structure, and the inner side and the outer side of the first bracket are both provided with openings; the second support is of a hollow structure, and only the inner side of the second support is provided with an opening. Through set up the opening in the inboard of second support, the outside does not set up the opening, can fix the test slide better, prevents that the test slide from sliding in the cavity between first support and second support.
Preferably, the height of the cavity is 0.8-3 mm, and the length of the cavity is 20-40 mm.
Preferably, the height of the cavity is 1-2 mm, and the length of the cavity is 25-36 mm.
Preferably, the width of the first bracket and the second bracket is 1-8 mm, preferably 4-6 mm.
Preferably, the width of the sample detection area is 10-20 mm, and preferably 14-16 mm; the length of the sample detection area is 20-30 mm, preferably 25-28 mm.
The utility model also provides a tissue sample rapid detection system, including dyeing kit, tissue sample detection device and microscope.
The utility model discloses tissue sample detection device and tissue sample rapid detection system have following advantage:
the utility model discloses a tissue sample detection device improves through the structure to traditional slide glass, has increased the sample detection zone, can be to the tow sides of tissue sample to the realization detects comprehensively the overall state of tissue, but the cell and the structure of different aspect of clear display. Through setting up slot and the cavity of fixed detection slide, can reduce the slip and the pollution risk of detecting the slide.
Adopt the utility model discloses when advancing the detection, tissue sample does not need the section, can directly observe organizational structure and cell form under the microscope, compares with traditional tissue slice technique, the utility model discloses the spatial structure and the spatial distribution information that have remain histiocyte to bigger degree have improved the accuracy that detects, have shortened check-out time.
Drawings
FIG. 1 is a front view of a tissue sample testing device;
FIG. 2 is a perspective view of a tissue sample testing device;
FIG. 3 is a side view of the tissue sample testing device;
FIG. 4 is a front view of a test slide;
FIG. 5 is a side view of a test slide;
wherein: 1-labeling zone, 2-first scaffold, 3-second scaffold, 4-sample detection zone, 5-clamping zone, 6-cavity, 7-slot, 8-detection slide, 801-upper slide, 802-lower slide.
Detailed Description
The utility model discloses a tissue sample detection device and tissue sample rapid detection system, the present document content can be used for reference to the technical staff in the field, and the technological parameter is suitably improved and is realized. It is expressly noted that all such substitutions and modifications which are obvious to a person skilled in the art are deemed to be included in the present invention. While the methods and applications of the present invention have been described in terms of preferred embodiments, it will be apparent to those skilled in the art that variations and modifications, or appropriate alterations and combinations, may be made to the methods and applications described herein without departing from the spirit and scope of the invention as defined by the appended claims.
The present invention will be further explained with reference to the following examples:
EXAMPLE 1 tissue sample detection device
The utility model discloses a tissue sample detection device contains fixing device and detecting element, fixing device comprises mark zone 1, grip block 5 and fixed area, the fixed area is located mark zone 1 with between the grip block 5, mark zone 1 is close to one side of fixed area with grip block 5 is close to one side of fixed area all is provided with slot 7, the fixed area comprises first support 2 and second support 3, first support 2 and second support 3 all are provided with the cavity 6 that holds detecting element, the rectangle that first support 2, second support 3, mark zone and grip block enclose is sample detection zone 4, detecting element is for detecting slide 8.
In one or more embodiments, the test slides are divided into an upper slide 801 and a lower slide 802, the tissue sample is placed between the upper slide 801 and the lower slide 802, and the test slide 8 with the tissue sample is placed in the cavities of the first rack 2 and the second rack 3.
In one or more embodiments, the marking area 1, the clamping area 5 and the fixing area are of an integrally formed structure, the first support 2 or the second support 3 of the fixing area is composed of a left support and a right support, and the left support or the right support is detachably connected.
In one or more of these embodiments, the width of the first bracket 2 and the second bracket 3 is 4mm, the height of the cavity of the first bracket 2 and the second bracket 3 is 1mm, and the length of the cavity 6 is 25 mm. The width of the sample detection zone 4 is 14mm and the length of the sample detection zone 4 is 25 mm.
In one or more of the embodiments, the width of the first bracket 2 and the second bracket 3 is 6mm, the height of the cavity of the first bracket 2 and the second bracket 3 is 2mm, and the length of the cavity 6 is 35 mm. The width of the sample detection zone 4 is 16mm and the length of the sample detection zone 4 is 28 mm.
Example 2 Rapid detection System for tissue samples
The utility model discloses a quick detecting system of tissue sample includes staining kit, tissue sample detection device and microscope.
The utility model discloses a tissue sample detection device contains fixing device and detecting element, fixing device comprises mark zone 1, grip block 5 and fixed area, the fixed area is located the mark zone with between the grip block, mark zone 1 is close to one side of fixed area with grip block 5 is close to one side of fixed area all is provided with slot 7, the fixed area comprises first support 2 and second support 3, first support 2 and second support 3 all are provided with the cavity 6 that holds detecting element, the rectangle that first support 2, second support 3, mark zone and grip block enclose is sample detection zone 4, detecting element is for detecting slide 8.
In one or more embodiments, the test slides are divided into an upper slide 801 and a lower slide 802, the tissue sample is placed between the upper slide 801 and the lower slide 802, and the test slide 8 with the tissue sample is placed in the cavities of the first rack 2 and the second rack 3.
In one or more embodiments, the marking area 1, the clamping area 5 and the fixing area are of an integrally formed structure, the first support 2 or the second support 3 of the fixing area is composed of a left support and a right support, and the left support or the right support is detachably connected.
In one or more of the embodiments, the width of the first bracket 2 and the second bracket 3 is 4mm, the height of the cavity 6 of the first bracket 2 and the second bracket 3 is 1mm, and the length of the cavity 6 is 25 mm. The width of the sample detection zone 4 is 14mm and the length of the sample detection zone 4 is 25 mm.
In one or more of the embodiments, the width of the first bracket 2 and the second bracket 3 is 6mm, the height of the cavity of the first bracket 2 and the second bracket 3 is 2mm, and the length of the cavity 6 is 35 mm. The width of the sample detection zone 4 is 16mm and the length of the sample detection zone 4 is 28 mm.
Detection example: placing the stained tissue sample on a lower glass slide 801 of a detection glass slide, dripping 90% glycerol to cover the tissue, and covering the tissue with an upper glass slide 802 of the detection glass slide; inserting a test slide containing a tissue sample into the fixture from a cavity in a side of the fixture; the tissue shape can be observed by turning the front and back surfaces of the tissue under a microscope. Adopt the utility model discloses a device carries out different planes to the tissue sample and shoots the image.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (10)
1. A tissue sample testing device, comprising a fixing device and a testing unit,
the fixing device consists of a mark area (1), a clamping area (5) and a fixing area, the fixing area is positioned between the mark area (1) and the clamping area (5), one side of the mark area (1) close to the fixing area and one side of the clamping area (5) close to the fixing area are both provided with slots (7), the fixing area consists of a first bracket (2) and a second bracket (3), the first bracket (2) and the second bracket (3) are both provided with cavities (6) for accommodating detection units, a rectangle formed by the first bracket (2), the second bracket (3), the mark area (1) and the clamping area (5) is a sample detection area (4),
the detection unit is a detection slide (8).
2. The tissue sample testing device according to claim 1, wherein said test slide (8) comprises an upper slide (801) and a lower slide (802), wherein the tissue sample is placed between said upper slide (801) and said lower slide (802), and wherein the test slide (8) containing the tissue sample is placed in the cavities of said first (2) and second (3) racks.
3. The tissue sample detection device according to any one of claims 1 or 2, wherein the marking zone (1), the holding zone (5) and the fixation zone are of an integrally formed structure.
4. The tissue sample testing device according to any of claims 1 or 2, wherein the first (2) or second (3) leg of the fixation section is comprised of a left leg and a right leg, the left leg or the right leg being detachably connected.
5. The tissue sample detection device according to any one of claims 1 to 4, wherein the first holder (2) is a hollow structure, and the inside and the outside of the first holder (2) are provided with openings; the second support (3) is of a hollow structure, and only the inner side of the second support (3) is provided with an opening.
6. The tissue sample detection device according to any one of claims 1 to 5, wherein the height of the cavity (6) is 0.8 to 3mm, and the length of the cavity (6) is 20 to 40 mm.
7. The tissue sample detection device according to claim 6, wherein the height of the cavity (6) is 1-2 mm, and the length of the cavity (6) is 25-36 mm.
8. The tissue sample detection device according to any one of claims 1 to 7, wherein the width of the first and second brackets (2, 3) is 1 to 8 mm.
9. The tissue sample detection device according to any one of claims 1 to 8, wherein the width of the sample detection area (4) is 10 to 20 mm; the length of the sample detection area (4) is 20-30 mm.
10. A rapid tissue sample detection system comprising a staining kit, the tissue sample detection device of any one of claims 1 to 9, and a microscope.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022169960.4U CN212871931U (en) | 2020-09-28 | 2020-09-28 | Tissue sample detection device and tissue sample rapid detection system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022169960.4U CN212871931U (en) | 2020-09-28 | 2020-09-28 | Tissue sample detection device and tissue sample rapid detection system |
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| Publication Number | Publication Date |
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| CN212871931U true CN212871931U (en) | 2021-04-02 |
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| CN202022169960.4U Active CN212871931U (en) | 2020-09-28 | 2020-09-28 | Tissue sample detection device and tissue sample rapid detection system |
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Effective date of registration: 20220530 Address after: 300410 Tianjin Beichen Science and Technology Park Patentee after: TASLY HOLDING GROUP Co.,Ltd. Address before: No.1-2, 7th floor, building 7, 733, 2nd section, Furong Avenue, Yongning Town, Wenjiang District, Chengdu, Sichuan 610000 Patentee before: Chengdu Tianshi Nuowei Biotechnology Co.,Ltd. |