CN217659940U - Carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform - Google Patents

Carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform Download PDF

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Publication number
CN217659940U
CN217659940U CN202123123628.5U CN202123123628U CN217659940U CN 217659940 U CN217659940 U CN 217659940U CN 202123123628 U CN202123123628 U CN 202123123628U CN 217659940 U CN217659940 U CN 217659940U
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sound attenuation
liquid
box body
blood vessel
ultrasonic
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王艺璇
李朝军
王蓓
曹萌萌
李菲
沙蕾
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Shanghai Jiading Jiangqiao Hospital
Shandong Qianfoshan Hospital
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Shanghai Jiading Jiangqiao Hospital
Shandong Qianfoshan Hospital
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Abstract

The utility model provides a carotid vulnerable plaque ultrasonic radiography quantitative evaluation experiment platform, which comprises a platform, be provided with the body mould box on the platform, the circulating pump, the liquid container of sound attenuation, a four-way reversing valve, peristaltic pump and quantitative liquid filler, be provided with the ultrasonic coupling piece between lid and the box body, the upper end of box body sets up the coupling, an ultrasonic radiography process for simulating the carotid, and then realize the quantitative evaluation to carotid vulnerable plaque, a structure is simple, and reasonable design has realized animal blood vessel or bionical blood vessel (can be ordinary rubber tube) at external ultrasonic radiography, experimental study for biomechanics provides convenience, also can be used to a plurality of experimental directions, like carotid ultrasonic radiography artifact study, novel ultrasonic machine external function verification, the external ultrasonic measurement of blood vessel animal experiment verifies etc..

Description

Carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform
Technical Field
The utility model relates to an experiment platform based on ultrasonic radiography technique, especially a carotid vulnerable plaque ultrasonic radiography quantitative evaluation experiment platform.
Background
Vulnerable plaque is an important pathogenic cause of cardiovascular and cerebrovascular events, and the pathological features of vulnerable plaque mainly include thin fibrous cap, large lipid core, many new vessels and strong inflammatory response. Ultrasound imaging can assess vulnerability by quantifying how much new blood vessels are present in the plaque. The vulnerability of the ultrasound contrast evaluation has certain limitations and is influenced by various factors, such as the body mass, the height, the blood pressure and the like of a patient. In addition, there is no uniform standard for the dosage of contrast agents; when the plaque is in an artery far field, an ultrasonic contrast artifact can be superposed in the plaque, and judgment of plaque vulnerability is further influenced. Therefore, there is a need for a carotid vulnerable plaque experimental model that can provide an experimental platform for ultrasound contrast study and assessment of vulnerable plaque.
There is also operator dependence on the quantitative assessment of carotid plaque ultrasound imaging. Experience and standardized training of the operator is a quality guarantee for vulnerable plaque assessment. In practice, the vulnerability assessment experience of accumulating carotid plaque needs a large sample of training, and manpower, material resources and financial resources are not allowed to be widely developed. Therefore, in order to promote and accurate quantitative aassessment to carotid artery plaque on a large scale, this patent has developed an experimental platform, can be used to the ultrasonic radiography process of simulation carotid, carries out external simulation experiment, and then accumulates relevant experience for medical personnel.
SUMMERY OF THE UTILITY MODEL
The utility model aims at the above problem, provide the vulnerable plaque ultrasonic radiography quantitative assessment experiment platform of carotid.
The specific technical scheme is as follows:
the carotid vulnerable plaque ultrasonic radiography quantitative evaluation experiment platform comprises a platform, and is characterized in that a body mould box, a circulating pump, a sound attenuation liquid container, a first four-way reversing valve, a peristaltic pump and a quantitative liquid feeder are arranged on the platform;
the body box comprises a box body and a box cover, the top of the box body is provided with an opening, the middle of the box cover is provided with a hole and is fixedly connected with the box body through a fastening screw, and an ultrasonic coupling sheet is arranged between the box cover and the box body;
the side surface of the box body is provided with a sound attenuation liquid inlet and a sound attenuation liquid outlet which are communicated with the interior of the box body and are used for sound attenuation liquid to enter and exit circulation, the sound attenuation liquid inlet is positioned below the sound attenuation liquid outlet, the sound attenuation liquid container is internally provided with prepared sound attenuation liquid, and the sound attenuation liquid container is provided with a sound attenuation liquid reflux inlet and a sound attenuation liquid supply outlet which are communicated with the inner wall of the sound attenuation liquid container and are used for sound attenuation liquid to enter and exit circulation; the sound attenuation liquid backflow inlet is positioned above the sound attenuation liquid supply outlet, the sound attenuation liquid backflow inlet is communicated with the sound attenuation liquid outlet through a hose, the sound attenuation liquid supply outlet is communicated with the sound attenuation liquid inlet through a hose, and the circulating pump is arranged between the sound attenuation liquid supply outlet and the sound attenuation liquid inlet;
the two sides of the upper end of the box body are provided with symmetrically arranged U-shaped clamping grooves, 2 detachable pipe joints are correspondingly arranged on the symmetrically arranged U-shaped clamping grooves, the inner wall of each U-shaped clamping groove is provided with a raised U-shaped clamping block, the middle part of each pipe joint is provided with a connecting block, the two ends of each pipe joint are respectively provided with a hose joint and a blood vessel joint, each connecting block is U-shaped and is matched with the U-shaped clamping groove, the outer wall of the U-shaped pipe joint is provided with a U-shaped bayonet, the U-shaped bayonet and the U-shaped clamping block are matched, the pipe joints are hermetically clamped on the box body through the connecting blocks and the U-shaped clamping grooves, the hose joints are communicated with the blood vessel joints, the hose joints are positioned outside the box body, and the blood vessel joints are positioned in the box body;
2 the pipe joints are divided into a liquid inlet pipe joint and a liquid outlet pipe joint according to functions, a first four-way reversing valve, a peristaltic pump and a quantitative liquid feeder are sequentially connected between a hose joint of the liquid inlet pipe joint and a hose joint of the liquid outlet pipe joint, and a blood vessel or a bionic blood vessel is connected between a blood vessel joint of the liquid inlet pipe joint and a blood vessel joint of the liquid outlet pipe joint;
the first four-way reversing valve is connected with a saline container for supplying saline, the saline container is filled with saline, the quantitative liquid feeder is filled with an ultrasonic contrast medium, and the ultrasonic contrast medium is quantitatively supplied;
further, a sealing strip is arranged in the U-shaped bayonet;
further, the blood vessel joint is a threaded detachable pipe joint;
furthermore, a sound absorption material is fixedly bonded on the inner wall of the box body of the body mould box;
furthermore, the center of the bottom surface of the box body is convex upwards in a semi-ellipsoidal shape, a plurality of sound absorption plates are uniformly distributed on the side surface of the box body, and the sound absorption plates are distributed longitudinally and transversely;
furthermore, a second four-way reversing valve is connected to a hose between the peristaltic pump and the quantitative liquid feeder, and the four-way reversing valve is respectively communicated with the cleaning liquid container and the waste liquid container;
furthermore, a control panel for controlling the operation of the pump, the valve and the quantitative liquid filler is arranged on the platform.
The beneficial effects of the utility model are that:
the utility model provides a carotid vulnerable plaque ultrasonic radiography quantitative evaluation experiment platform, which comprises a platform, be provided with the body mould box on the platform, the circulating pump, the liquid container of sound attenuation, a four-way reversing valve, peristaltic pump and quantitative liquid filler, be provided with the ultrasonic coupling piece between lid and the box body, the upper end of box body sets up the coupling, an ultrasonic radiography process for simulating the carotid, and then realize the quantitative evaluation to carotid vulnerable plaque, a structure is simple, and reasonable design has realized animal blood vessel or bionical blood vessel (can be ordinary rubber tube) at external ultrasonic radiography, experimental study for biomechanics provides convenience, also can be used to a plurality of experimental directions, like carotid ultrasonic radiography artifact study, novel ultrasonic machine external function verification, the external ultrasonic measurement of blood vessel animal experiment verifies etc..
Drawings
Fig. 1 is a schematic view of the present invention.
Figure 2 is a schematic view of a phantom cartridge.
Fig. 3 is a schematic view of a U-shaped card slot.
Fig. 4 is a schematic view of a pipe joint.
Fig. 5 is a schematic longitudinal sectional view of the cartridge body.
Fig. 6 is a schematic longitudinal cross-sectional view of the cartridge (bonded sound absorber).
Fig. 7 is a schematic longitudinal sectional view of the cartridge (physical structure improvement).
The reference numbers indicate: 1. a platform; 2. a body mold box; 3. a circulation pump; 4. a sound attenuation liquid container; 5. a first four-way reversing valve; 6. a peristaltic pump; 7. a quantitative liquid adding device; 8. a case body; 9. a box cover; 10. a fastening screw; 11. an ultrasonic coupling sheet; 12. a sound attenuation liquid inlet; 13. a sound attenuation liquid outlet; 14. the sound attenuation liquid flows back to the inlet; 15. a sound attenuation liquid supply outlet; 16. a U-shaped clamping groove; 17. a pipe joint; 18. a U-shaped clamping block; 19. connecting blocks; 20. a hose connector; 21. a vascular junction; 22. a U-shaped bayonet; 23. a liquid inlet pipe joint; 24. a liquid outlet pipe joint; 25. a physiological saline container; 26. a seal strip; 27. a sound absorbing material; 28. a sound absorbing panel; 29. a second four-way reversing valve; 30. a cleaning solution container; 31. a waste liquid container; 32. a control panel.
Detailed Description
For making the technical scheme of the utility model clear more, it is right to combine the embodiment below the utility model discloses it is further described, any right the utility model discloses technical scheme's technical characteristics carry out the scheme that equivalent replacement and conventional reasoning reachs and all fall into the utility model discloses scope of protection.
Example one
The carotid vulnerable plaque ultrasonic radiography quantitative evaluation experiment platform comprises a platform 1, and is characterized in that a body mold box 2, a circulating pump 3, a sound attenuation liquid container 4, a first four-way reversing valve 5, a peristaltic pump 6 and a quantitative liquid filler 7 are arranged on the platform 1;
the body mould box 2 comprises a box body 8 and a box cover 9, the top of the box body 8 is provided with an opening, the middle part of the box cover 9 is provided with a hole and is fixedly connected with the box body 8 through a fastening screw 10, and an ultrasonic coupling piece 11 is arranged between the box cover 9 and the box body 8; the ultrasonic coupling piece 11 is clamped and fixed between the box cover 9 and the box body 8, and the opening at the top of the box body 8 is sealed and closed;
the side surface of the box body 8 is provided with a sound attenuation liquid inlet 12 and a sound attenuation liquid outlet 13 which are communicated with the inside of the box body 8 and are used for sound attenuation liquid inlet and outlet circulation, the sound attenuation liquid inlet 12 is positioned below the sound attenuation liquid outlet 13, the sound attenuation liquid container 4 is internally stored with prepared sound attenuation liquid, and the sound attenuation liquid reflux inlet 14 and the sound attenuation liquid supply outlet 15 which are communicated with the inner wall of the sound attenuation liquid container 4 and are used for sound attenuation liquid inlet and outlet circulation are arranged; the sound attenuation liquid backflow inlet 14 is positioned above the sound attenuation liquid supply outlet 15, the sound attenuation liquid backflow inlet 14 is communicated with the sound attenuation liquid outlet 13 through a hose, the sound attenuation liquid supply outlet 15 is communicated with the sound attenuation liquid inlet 12 through a hose, and the circulating pump 3 is arranged between the sound attenuation liquid supply outlet 15 and the sound attenuation liquid inlet 12; when needing to carry out ultrasonic contrast ration aassessment experiment, need inject sound attenuation liquid in advance to phantom box 2 to the tissue density of simulation people or animals, sound attenuation liquid gets into body mould box 2 from sound attenuation liquid container 4 through the circulating pump, and with in the body mould box 2 air evacuation after, return to in the sound attenuation liquid container 4, so far, be full of sound attenuation liquid in the phantom box 2, wherein, the sound attenuation liquid of simulation tissue density is with 1 by glycerine and water: 1, and the attenuation coefficient is 0.3dB/cm/MHz;
the two sides of the upper end of the box body 8 are provided with symmetrically arranged U-shaped clamping grooves 16, the symmetrically arranged U-shaped clamping grooves 16 are correspondingly provided with 2 detachable pipe joints 17, the inner wall of each U-shaped clamping groove 16 is provided with a raised U-shaped clamping block 18, the middle part of each pipe joint 17 is provided with a connecting block 19, the two ends of each pipe joint are respectively provided with a hose connector 20 and a blood vessel connector 21, each connecting block 19 is U-shaped and is matched with the U-shaped clamping groove 16, the outer wall of the U-shaped pipe joint is provided with a U-shaped bayonet 22, the U-shaped bayonet 22 is matched with the U-shaped clamping block 18, the pipe joints 17 are hermetically clamped on the box body 8 through the connecting blocks 19 and the U-shaped clamping grooves 16, the hose connectors 20 are communicated with the blood vessel connectors 21, the hose connectors 20 are positioned outside the box body 8, and the blood vessel connectors 21 are positioned in the box body 8; the design of the U-shaped clamping groove enables the pipe joints to be accurately butted and to be stable and sealed enough, and meanwhile, the pipe joints are convenient to detach, clean and replace;
2 pipe joints 17 are divided into a liquid inlet pipe joint 23 and a liquid outlet pipe joint 24 according to functions, a first four-way reversing valve 5, a peristaltic pump 6 and a quantitative liquid filler 7 are sequentially connected between a hose joint 20 of the liquid inlet pipe joint 23 and a hose joint 20 of the liquid outlet pipe joint 24, and a blood vessel or a bionic blood vessel is connected between a blood vessel joint 21 of the liquid inlet pipe joint 23 and a blood vessel joint 21 of the liquid outlet pipe joint 24; the first four-way reversing valve 5 is connected with a physiological saline container 25 for supplying physiological saline, the physiological saline container 25 contains physiological saline, and the quantitative liquid feeder 7 contains an ultrasonic contrast medium for quantitatively supplying the ultrasonic contrast medium; when an ultrasonic contrast quantitative evaluation experiment is carried out, before acoustic attenuation liquid is filled, a blood vessel or a bionic blood vessel is connected between the liquid inlet pipe joint 23 and the liquid outlet pipe joint 24 (located in the body mould box 2) in advance, after the acoustic attenuation liquid is filled, normal saline in the normal saline container 25 can be introduced into the body mould box 2 until the normal saline reaches circulation among the peristaltic pump 3, the quantitative liquid feeder 7 and the blood vessel (or the bionic blood vessel) in the body mould box 2, at the moment, the supply of the normal saline can be stopped, in the circulation process of the normal saline, the quantitative liquid feeder 7 works, ultrasonic contrast agents are uniformly injected into the circulating normal saline, and accordingly, an experimenter can scan the position of an ultrasonic coupling piece through an ultrasonic probe and carry out experiment operation.
The carotid vulnerable plaque ultrasonic radiography quantitative evaluation experiment platform of the embodiment is used for simulating the carotid ultrasonic radiography process, further realizing the quantitative evaluation of carotid vulnerable plaques, and is simple in structure and reasonable in design, the ultrasonic radiography of animal blood vessels or bionic blood vessels (which can be common rubber tubes) in vitro is realized, the experiment research of biomechanics is facilitated, and the carotid vulnerable plaque ultrasonic radiography experiment platform can be used for multiple experiment directions, such as carotid ultrasonic radiography artifact research, novel ultrasonic machine external function verification, blood vessel animal experiment external ultrasonic measurement verification and the like.
Example two
In order to ensure the sealing performance of the position of the safe connector, the carotid vulnerable plaque ultrasonic angiography quantitative evaluation experiment platform of the embodiment is provided with a sealing strip 26 at the U-shaped bayonet 22; meanwhile, in order to facilitate the connection of the blood vessels (including the bionic blood vessel) passing through the pipe diameter, the blood vessel joint 21 adopts a threaded detachable pipe joint.
EXAMPLE III
According to the carotid vulnerable plaque ultrasonic radiography quantitative evaluation experiment platform, a sound absorption material 27 is fixedly bonded on the inner wall of the box body 8 of the body mould box 2; therefore, the influence of a large amount of reflection of sound waves in the body model box 2 on the precision of an ultrasonic experiment in the ultrasonic process is eliminated;
meanwhile, besides the sound absorption material 27, sound absorption can also be performed by adjusting the physical structure of the body mold box 2, for example, the center of the bottom surface of the box body 8 is improved to a semi-ellipsoidal upward convex state, so that sound waves are reflected to the side surface of the box body 8, and a plurality of sound absorption plates 28 are uniformly distributed on the side surface of the box body 8, and the sound absorption plates 28 are vertically and horizontally distributed, so as to perform sound absorption treatment;
of course, the sound absorption effect is better by combining the arrangement of the sound absorption material 27 and the improvement of the physical structure of the box body 8.
Example four
In the carotid vulnerable plaque ultrasonic angiography quantitative evaluation experiment platform of the embodiment, a hose between the peristaltic pump 6 and the quantitative liquid feeder 7 is connected with a second four-way reversing valve 29, the four-way reversing valve is respectively communicated with a cleaning liquid container 30 and a waste liquid container 31, and a control panel 32 for controlling the operation of the pump, the valve and the quantitative liquid feeder 7 is arranged on the platform 1;
when the experiment is completed, a cleaning liquid is continuously injected into the pipe of the experimental circulation to clean the pipe, the waste liquid is recovered in the waste liquid container 31, and the cleaning liquid stored in the cleaning liquid container 30 is normal saline or pure water (normal saline is the most preferable).
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention should be covered by the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (7)

1. The carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform comprises a platform (1), and is characterized in that a body mould box (2), a circulating pump (3), a sound attenuation liquid container (4), a first four-way reversing valve (5), a peristaltic pump (6) and a quantitative liquid feeder (7) are arranged on the platform (1);
the body mould box (2) comprises a box body (8) and a box cover (9), the top of the box body (8) is provided with an opening, the middle part of the box cover (9) is provided with a hole and is fixedly connected with the box body (8) through a fastening screw (10), and an ultrasonic coupling piece (11) is arranged between the box cover (9) and the box body (8);
a sound attenuation liquid inlet (12) and a sound attenuation liquid outlet (13) which are communicated with the interior of the box body (8) and are used for sound attenuation liquid to enter and exit circulation are formed in the side face of the box body (8), the sound attenuation liquid inlet (12) is positioned below the sound attenuation liquid outlet (13), prepared sound attenuation liquid is stored in the sound attenuation liquid container (4), and a sound attenuation liquid backflow inlet (14) and a sound attenuation liquid supply outlet (15) which are communicated with the inner wall of the sound attenuation liquid container (4) and are used for sound attenuation liquid to enter and exit circulation are formed in the sound attenuation liquid container (4); the sound attenuation liquid backflow inlet (14) is positioned above the sound attenuation liquid supply outlet (15), the sound attenuation liquid backflow inlet (14) is communicated with the sound attenuation liquid outlet (13) through a hose, the sound attenuation liquid supply outlet (15) is communicated with the sound attenuation liquid inlet (12) through a hose, and the circulating pump (3) is arranged between the sound attenuation liquid supply outlet (15) and the sound attenuation liquid inlet (12);
the blood vessel connector is characterized in that U-shaped clamping grooves (16) which are symmetrically arranged are formed in two sides of the upper end of the box body (8), 2 detachable pipe joints (17) are correspondingly arranged on the U-shaped clamping grooves (16) which are symmetrically arranged, raised U-shaped clamping blocks (18) are arranged on the inner wall of each U-shaped clamping groove (16), a connecting block (19) is arranged in the middle of each pipe joint (17), two ends of each connecting block are respectively provided with a hose connector (20) and a blood vessel connector (21), each connecting block (19) is U-shaped and is matched with the U-shaped clamping groove (16), a U-shaped bayonet (22) is formed in the outer wall of the U-shaped pipe joint (17), the U-shaped bayonet (22) is matched with the U-shaped clamping blocks (18), the pipe joints (17) are hermetically clamped on the box body (8) through the connecting blocks (19) and the U-shaped clamping grooves (16), the hose connectors (20) are communicated with the blood vessel connectors (21), the hose connectors (20) are located outside the box body (8), and the blood vessel connectors (21) are located in the box body (8);
(2) The pipe joints (17) are divided into a liquid inlet pipe joint (23) and a liquid outlet pipe joint (24) according to functions, a first four-way reversing valve (5), a peristaltic pump (6) and a quantitative liquid adding device (7) are sequentially connected between a hose joint (20) of the liquid inlet pipe joint (23) and a hose joint (20) of the liquid outlet pipe joint (24), and a blood vessel or a bionic blood vessel is connected between a blood vessel joint (21) of the liquid inlet pipe joint (23) and a blood vessel joint (21) of the liquid outlet pipe joint (24);
the first four-way reversing valve (5) is connected with a saline container (25) for supplying saline, the saline container (25) is filled with saline, and the quantitative liquid feeder (7) is filled with an ultrasonic contrast agent for quantitatively supplying the ultrasonic contrast agent.
2. The carotid vulnerable plaque ultrasonic contrast quantitative assessment experiment platform according to claim 1, characterized in that a sealing strip (26) is arranged in the U-shaped bayonet (22).
3. The carotid vulnerable plaque ultrasound contrast quantitative assessment experimental platform of claim 1, characterized in that said vessel connector (21) is a threaded detachable tube connector.
4. The carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform according to claim 1, characterized in that a sound absorption material (27) is fixedly bonded on the inner wall of the body (8) of the body mold box (2).
5. The carotid vulnerable plaque ultrasonic contrast quantitative evaluation experimental platform according to claim 1 or 4, characterized in that the center of the bottom surface of the box body (8) is convex upwards in a semi-ellipsoidal shape, and a plurality of sound absorption plates (28) are uniformly distributed on the side surface of the box body, and the sound absorption plates (28) are distributed vertically and horizontally.
6. The carotid vulnerable plaque ultrasonic contrast quantitative evaluation experimental platform of claim 1, characterized in that a second four-way reversing valve (29) is connected to the hose between the peristaltic pump (6) and the quantitative liquid charger (7), and the four-way reversing valve is respectively communicated with the cleaning liquid container (30) and the waste liquid container (31).
7. The carotid vulnerable plaque ultrasound contrast quantitative assessment experimental platform according to claim 6, characterized in that said platform (1) is provided with a control panel (32) for controlling the operation of the pumps, valves and quantitative liquid charger (7).
CN202123123628.5U 2021-12-13 2021-12-13 Carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform Active CN217659940U (en)

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Application Number Priority Date Filing Date Title
CN202123123628.5U CN217659940U (en) 2021-12-13 2021-12-13 Carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202123123628.5U CN217659940U (en) 2021-12-13 2021-12-13 Carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform

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Publication Number Publication Date
CN217659940U true CN217659940U (en) 2022-10-28

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CN202123123628.5U Active CN217659940U (en) 2021-12-13 2021-12-13 Carotid vulnerable plaque ultrasonic contrast quantitative evaluation experiment platform

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